Kiri

EURGen-Net Network Meeting 2024 25–26 September 2024 1/4 European Centre for Disease Prevention and Control (ECDC) Gustav den III:s Boulevard 40, 169 73 Solna, Sweden Phone: +46 (0)8 58 60 10 00 - Fax: +46 (0)8 58 60 10 01

www.ecdc.europa.eu

European Antimicrobial Resistance Genes Surveillance Network (EURGen-Net) network meeting 2024

25–26 September 2024

Agenda

EURGen-Net Network Meeting 2024 25–26 September 2024 2/4 European Centre for Disease Prevention and Control (ECDC) Gustav den III:s Boulevard 40, 169 73 Solna, Sweden Phone: +46 (0)8 58 60 10 00 - Fax: +46 (0)8 58 60 10 01

www.ecdc.europa.eu

Scope and purpose The purpose of this virtual meeting is to provide the EURGen-Net Operational Contact Points (and Contact Points for Operations) and the National Focal Points for Antimicrobial Resistance (and Observer National Focal Points for Antimicrobial Resistance) with updates on ongoing ECDC activities related to molecular surveillance of bacteria of public health importance.

Day 1 will provide updates on current and potential activities related to carbapenem-resistant Enterobacterales (CRE). Day 2 is the ‘kick-off meeting’ for the ‘ECDC survey of carbapenem-resistant Acinetobacter baumannii 2024/2025’, presenting and discussing the published ECDC survey protocol and laboratory manual.

EURGen-Net Network Meeting 2024 25–26 September 2024 3/4 European Centre for Disease Prevention and Control (ECDC) Gustav den III:s Boulevard 40, 169 73 Solna, Sweden Phone: +46 (0)8 58 60 10 00 - Fax: +46 (0)8 58 60 10 01

www.ecdc.europa.eu

Wednesday 25 September 2024

10:00 – 10:15 EURGen-Net network meeting: Welcome Dominique Monnet (ECDC)

Session 1 - European Reference Laboratory for Antimicrobial Resistance (EURL-PH-AMR) Moderator: Daniel Palm (ECDC)

10:15 – 10:30 Introduction to European Reference Laboratories for Public Health Yoline Kuipers (DG SANTE)

10:30 – 11:00 Overview of the planned activities of the EURL-PH-AMR Anders Rhod Larsen, Camilla Wiuff Coia (Statens Serum Institut)

11:00 - 11:15 Communication between EURL-PH-AMR and EURGen-Net Nina Lagerqvist (ECDC)

11:15 – 11:25 Break

Session 2 – Update on ECDC activities, contracts and collaborations Moderator: Anke Kohlenberg (ECDC)

11:25 – 11:40 Presentation of Institut Pasteur Biological Resource Center Fay Betsou, Mariana Ferrari (Institut Pasteur)

11:40 – 11:55

Antimicrobial resistance in Ukraine: challenges of war Artem Horbachevskii (Public Health Centre of the MoH of Ukraine)

11:55 – 12:10

ECDC whole genome sequencing support Saara Kotila (ECDC)

12:10 – 12:30 Epipulse cases update Erik Alm (ECDC)

12:30 – 13:30 Lunch break

Carbapenem-resistant Enterobacterales (CRE)

Session 3 – Planning of future CRE surveillance Moderator: Barbara Albiger (ECDC)

13:30 – 13:45 Pathogen genomic surveillance: the way forward Marc Struelens (Université Libre de Bruxelles, Belgium)

13:45 – 14:30 Protocol for the CRE25 survey Anke Kohlenberg (ECDC)

14:30 – 14:40 Break

Session 4 – National and EU-level investigations of outbreaks and emerging resistance Moderator: Diamantis Plachouras (ECDC)

14:40– 15:00

Investigation of NDM-1-producing Providencia stuartii in Romania Daniela Tălăpan (National Institute of Infectious Diseases “Prof Dr Matei Bals”, Romania), Marius Linkevicius (ECDC)

15:00 – 15:20

European investigation of Escherichia coli ST131 carrying carbapenemase genes Anke Kohlenberg, Marius Linkevicius (ECDC)

15:20– 15:45 EpiPulse presentation Stefania De Angelis (ECDC)

15:45 – 15:55

Cross-border spread of hybrid resistance and virulence plasmid Anke Kohlenberg, Marius Linkevicius (ECDC)

15:55 – 16:00 AOB and closure Anke Kohlenberg (ECDC)

EURGen-Net Network Meeting 2024 25–26 September 2024 4/4 European Centre for Disease Prevention and Control (ECDC) Gustav den III:s Boulevard 40, 169 73 Solna, Sweden Phone: +46 (0)8 58 60 10 00 - Fax: +46 (0)8 58 60 10 01

www.ecdc.europa.eu

Thursday 26 September 2024

Day 2 of the EURGen-Net network meeting is the kick-off meeting for the ECDC CRAb survey, 2024—2025, which has a survey period from 01/10/2024—30/06/2025. Attendees can propose topics for interactive sessions in ≥ 3 ways:

1. During the meeting using the chat, or by speaking.

2. Before the meeting by email (to: [email protected]; [email protected]). At the meeting, ECDC will not share the names the people who sent the emails.

3. Preferably by 13 September, using an anonymous & short online ECDC survey. URL: https://ec.europa.eu/eusurvey/runner/CRAb_kickoff_meeting_survey

09:30 Virtual room opens

Session 5 – CRAb kick-off meeting: INITIAL SESSION (10:00–11:10)

10:00 Welcome; launch of survey; CRAb-survey-related updates; adoption of the meeting agenda. Pete Kinross (ECDC)

10:10 Brief overview of the survey materials, i.e. the survey protocol, the laboratory manual, and (Excel) data entry tool.

Pete Kinross, Andreas Hoefer (ECDC)

10:15 Brief practical presentation of the Excel data entry tool Pete Kinross (ECDC)

10:20 Immediate questions and requests for clarification Group (ECDC moderates)

10:30 An introduction from Institut Pasteur, the ECDC contractor for strain collection for the CRAb-survey

Mariana Ferrari, Fay Betsou (CRBIP, Paris, FR)

10:50 Summary of all CRAb survey-related ‘frequently asked questions’ (FAQs); Introduction to the main session and afternoon session.

Pete Kinross; Andreas Hoefer (ECDC)

11:00 Immediate questions, and requests for clarification; and gather additional topics for the next sessions Group (ECDC moderates)

11:10 Coffee break Session 6 – CRAb kick-off meeting: MAIN Q&A SESSION (11:30–12:30)

Note: you can propose topics now using the EUSurvey hyperlink*

11:30 Open floor Q&A session Group (ECDC moderates)

12:20 Summary of meeting and next steps; close of meeting. Pete Kinross, Andreas Hoefer (ECDC)

12:30 End of meeting. Note: the virtual room will remain open from 12:30–13:30 ECDC remains online 13:30 Virtual meeting room closes 13:55 Virtual meeting room reopens OPTIONAL: AFTERNOON GROUP SESSIONS or BILATERAL SESSIONS (14:00–17:00)

Use the EUSurvey* to propose CRAb-related topic(s), and/or a bilateral meeting; and to indicate your availability

14:00 Optional session 1 ECDC moderates 14:30 Optional session 2 ECDC moderates 15:00 Optional session 3 ECDC moderates 15:30 Optional session 4 ECDC moderates 16:00 Optional session 5 ECDC moderates 16:30 Coffee break

16:45 Review of afternoon session; summary of next steps. Pete Kinross, Andreas Hoefer (ECDC)

17:00 End of optional afternoon session. ECDC remains online 17:15 Virtual meeting room closes

* EU Survey: https://ec.europa.eu/eusurvey/runner/CRAb_kickoff_meeting_survey

1/1 European Centre for Disease Prevention and Control (ECDC) Gustav den III:s Boulevard 40, 169 73 Solna, Sweden Phone: +46 (0)8 58 60 10 00 - Fax: +46 (0)8 58 60 10 01

www.ecdc.europa.eu

ECDC NORMAL

Stockholm, 23 September 2024

Our ref: MET-000193

Dear colleague,

Re: Virtual network meeting of the European Antimicrobial Resistance Genes Surveillance Network (EURGen-Net) 2024

The European Centre for Disease Prevention and Control (ECDC) invites you to participate in the above- mentioned virtual meeting.

Time:

• Wednesday, 25 September 2024, 10:00 – 16:00 CET Topics: EURGen-Net general topics; ECDC carbapenem-resistant Enterobacterales (CRE) focus

• Thursday, 26 September 2024, 10:00 – 17:00 CET Topic: ‘Kick-off meeting’ for the ‘ECDC survey of carbapenem-resistance Acinetobacter baumannii 2024/2025’

Purpose of the meeting:

• To provide the EURGen-Net Operational Contact Points (and Contact Points for Operations) and the National Focal Points for Antimicrobial Resistance (and observer National Focal Points for Antimicrobial Resistance) with updates on ongoing ECDC activities related to molecular surveillance. Day 1 will provide updates on current and potential activities related to CCREs. Day 2 is the ‘kick-off meeting’ for the ‘ECDC survey of carbapenem-resistance Acinetobacter baumannii 2024/2025’, presenting and discussing the published ECDC survey protocol and laboratory manual.

Please note that this invitation is personal and non-transferable. Please find the meeting agenda attached.

All participants are required to have a Declaration of Interest in accordance with the ECDC policy on scientific integrity and independence to attend the first day of the meeting. This is to ensure that there are no conflicts of interest which could impair the independence of ECDC’s activities. If you receive this letter then ECDC has already validated your DoI. If you are unsure, please email [email protected]

If you are a designated speaker during the meeting, you are not required to have a valid DoI. We ask to introduce yourself to the audience at the beginning of your presentation.

Please be informed that this meeting will be recorded, to aid production of the minutes.

Thank you in advance for your commitment to this ECDC activity.

Yours sincerely, 21/09/2024

X Ole Heuer Ole Heuer Head of Unit Disease Programmes Signed by: Ole Heuer

Encl.: Meeting agenda

Disclaimer: No reimbursement by ECDC is foreseen for participation in virtual meetings. Should the invitee have incurred costs in relation to a virtual meeting, the invitee is responsible for such costs.