Arvamus eelnõu kohta
| Dokumendiregister | Sotsiaalministeerium |
| Viit | 1.2-2/2-7 |
| Registreeritud | 29.01.2026 |
| Sünkroonitud | 30.01.2026 |
| Liik | Sissetulev kiri |
| Funktsioon | 1.2 Õigusloome ja õigusalane nõustamine |
| Sari | 1.2-2 Ministeeriumis väljatöötatud õigusaktide eelnõud koos seletuskirjadega (Arhiiviväärtuslik) |
| Toimik | 1.2-2/2025 |
| Juurdepääsupiirang | Avalik |
| Juurdepääsupiirang | |
| Adressaat | Ravimiamet |
| Saabumis/saatmisviis | Ravimiamet |
| Vastutaja | Liisi Lillipuu (Sotsiaalministeerium, Kantsleri vastutusvaldkond, Innovatsiooni vastutusvaldkond, Arendusosakond) |
| Originaal | Ava uues aknas |
Failid
Tähelepanu! Tegemist on välisvõrgust saabunud kirjaga. |
Teie: 06.01.2026 nr 1.2-2/2-1
Meie: 28.01.2026 nr JUR-3/128-2
Tere
Ravimiametil on eelnõule kaks kommentaari:
1. Failis „SK_LISA2_rakendusaktide_kavandid_20251208.pdf“ lk 8 ja 9 punk § 9 lg 15 punkt 1 on sätestatud, et
Ravimiamet edastab infosüsteemi: 1) teavet rakkude ja kudede hankimise, käitlemise ja siirdamise loa omajatest;
Korrektne on:
Ravimiamet edastab infosüsteemi: 1) teavet rakkude ja kudede hankimise ja käitlemise tegevusloa omajatest;
2. Vastavalt SoHO määruse 2024/1938 artiklile 31 tuleb liikmesriikidel SoHO platvormile esitama hakata käitlemisandmeid, mis suure tõenäosusega põhinevad varasemalt välja töötatud EDQM-i andmekoosseisudel. Failis „SK_LISA3_rakendusaktide_kavandid_20251208.pdf“ esitatud Viljatusravi ja suguraku doonorluse teatise andmekoosseis tundub EDQM-i andmekoosseisuga esialgsel hindamisel üldiselt sobivat, kuid vaja oleks lisada veel üks andmeväli, mis sobiks „Viljatusravi ja suguraku doonorluse teatise andmekoosseis“ punkti 13. alla. Näiteks nii:
13.13. inimeste arv, kellele munasarjakude siirdati.
Põhjendus: See vastab EDQM-i andmekoosseisus esitatud andmeväljale FP a 9 # of patients who underwent an ovarian tissue transplantation, mis ei tundu hetkel andmekoosseisuga kaetud olevat.
Lisan kirjale ka EDQM andmekoosseisu sisaldava faili. Viljatusravi puudutav osa on lk 12-14.
Muus osas Ravimiametil tähelepanekuid ei ole.
Lugupidamisega
Andrus Varki
Ravimiamet
Õigusosakonna juhataja
+372 737 4140
+372 737 4142
[email protected]
Nooruse 1
50411 Tartu
www.ravimiamet.ee
Selles e-kirjas sisalduv teave (kaasa arvatud manused) on mõeldud ametialaseks kasutamiseks ning seda võivad kasutada vaid e-kirja adressaadid. E-kirjas sisalduvat teavet ei tohi ilma saatja selgelt väljendatud loata edasi
saata ega mis tahes viisil kolmandatele isikutele avaldada. Juhul, kui Te olete saanud käesoleva e-kirja eksituse tõttu, teavitage sellest koheselt saatjat ning kustutage e-kiri.
This e-mail and any attachments transmitted may contain confidential and privileged information. If you are not the intended recipient, please notify the sender immediately by returning the e-mail and permanently deleting what you have received. Any dissemination
or use of this information by a third person without permission is prohibited and may be illegal.
COUNTRY Year
NUMBERS
NUMBERS
Donations
# of containers
Sclera # of containers
Releases for clinical application, whether distributed or not
Cornea, full thickness (high endothelial cell density)
Other ocular
Distributed to end user in the country
Cornea, full thickness (high endothelial cell density) # of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2 Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment) # of corneas Sclera # of containers Other ocular # of containers
REPLACEMENT TISSUES ACTIVITY DATA
OCULAR TISSUE UNITS/EXPLANATIONS
# of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2
O C
U LA
R
Donors
DONORS (COLLECTED AT NATIONAL LEVEL)
Deceased donors Living donors
Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment) # of corneas Sclera # of containers
Living donors # of living ocular tissue/cell donors at national level Deceased donors # of deceased ocular tissue/cell donors at national level Ocular tissue donations # of donation events from one donor, may include 1 or 2 eyes/corneas
Distributed to end user in another EU country
Cornea, full thickness (high endothelial cell density) # of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2 Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment) # of corneas
Received from a tissue establishment (transport) in
another EU country
Cornea, full thickness (high endothelial cell density) # of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2
Sclera # of containers Other ocular # of containers
Sent to a tissue establishment (transport) in another EU country
Cornea, full thickness (high endothelial cell density) # of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2 Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment)
Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment) # of corneas
Other ocular # of containers
# of corneas Sclera # of containers Other ocular # of containers
# of containers
Imports (non EU)
Cornea, full thickness (high endothelial cell density) # of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2 Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment) # of corneas Sclera # of containers
Exports (non EU)
Cornea, full thickness (high endothelial cell density) # of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2 Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment) # of corneas Sclera # of containers Other ocular
Other ocular # of containers
# of deceased tissue/cell donors at national level # of living tissue/cell donors at national level
UNITS/EXPLANATIONS
OC 2 OC 1
OC 3 OC 4 OC 5 OC 6 OC 7 OC 8
OC 18 OC 19 OC 20 OC 21 OC 22 OC 23 OC 24 OC 25 OC 26
OC 9 OC 10 OC 11 OC 12 OC 13 OC 14 OC 15 OC 16 OC 17
OC 36 OC 37 OC 38
OC 27 OC 28 OC 29 OC 30 OC 31 OC 32 OC 33 OC 34 OC 35
DD LD
PA/PH/TO (21) 02 2 of 14 Work Package 7 / GA 2018 53 01
NUMBERS
Donations
NUMBERS
Donations
Amniotic membrane eyedrops # of batches prepared for a single patient
Amniotic membrane eyedrops # of batches prepared for a single patient
Amniotic membrane eyedrops # of batches prepared for a single patient
Amniotic membrane eyedrops # of batches prepared for a single patient
Amniotic membrane # of containers
Other placental # of containers # of containers
Other placental # of containers Amniotic membrane # of containers
Other placental # of containers
PL A
C EN
TA L
Donors
Donors
Releases for clinical application, whether distributed or not
Distributed to end user in the country
Sent to a tissue establishment (transport) in another EU country
Exports (non EU)
Releases for clinical application, whether distributed or not
Amniotic membrane
Distributed to end user in another EU country
Amniotic membrane
Amniotic membrane
Living donors
Skin
Deceased donors # of deceased placental tissue donors at national level
Application procedures
Applications for Penetrating Keratoplasty # of applications (one surgical procedure, regardless of the # of grafts used) Applications for Anterior Lamellar Keratoplasty # of applications (one surgical procedure, regardless of the # of grafts used) Applications for Endothelial Keratoplasty # of applications (one surgical procedure, regardless of the # of grafts used)
# of containers
Other placental # of containers
Imports (non EU)
Amniotic membrane # of containers
Other placental # of containers
Amniotic membrane eyedrops # of batches prepared for a single patient
Amniotic membrane eyedrops # of batches prepared for a single patient
Applications for scleral reconstruction
Placental membrane donations # of donation events from one delivery, including multiple births
Amniotic membrane eyedrops # of batches prepared for a single patient
Received from a tissue establishment (transport) in
another EU country
Amniotic membrane # of containers
Other placental # of containers
# of containers
Other placental # of containers
# of applications (one surgical procedure, regardless of the # of grafts used) Applications for other ocular treatments (only use if the application does not fit into one of the above categories) # of applications (one surgical procedure, regardless of the # of grafts used)
PLACENTAL TISSUE UNITS/EXPLANATIONS
Living donors # of living placental tissue donors at national level
# of living cutaneous tissue donors at national level Deceased donors # of deceased cutaneous tissue donors at national level Skin donations # of donation events from one donor, regardless of the number of tissues obtained
Amniotic membrane applications for ocular treatment (excluding amniotic eye drops) # of applications (one surgical procedure, regardless of the # of grafts used)
Amniotic membrane applications for other treatments # of applications (one surgical procedure, regardless of the # of grafts used)
CUTANEOUS TISSUE UNITS/EXPLANATIONS
Amniotic membrane applications for non-ocular burn/wound healing # of applications (one surgical procedure, regardless of the # of grafts used) Amniotic membrane applications for ocular treatment (amniotic eye drops) # of batches prepared for a single patient
Other placental tissue applications (only use if the application does not fit into one of the above categories) # of applications (one surgical procedure, regardless of the # of grafts used)
Application procedures
cm2 Acellular dermal matrix cm2 Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
Distributed to end user in the country
Skin cm2 Acellular dermal matrix cm2 Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
OC 39 OC 40 OC 41 OC 42 OC 43
PL 1
PL 11 PL 12 PL 13 PL 14 PL 15 PL 16 PL 17 PL 18 PL 19
PL 2 PL 3 PL 4 PL 5 PL 6 PL 7 PL 8 PL 9
PL 10
PL 29
CU 1 CU 2 CU 3 CU 4 CU 5 CU 6 CU 7 CU 8
PL 20 PL 21 PL 22 PL 23 PL 24 PL 25 PL 26 PL 27 PL 28
CU 9 CU 10 CU 11
Work Package 7 / GA 2018 53 01 3 of 14 PA/PH/TO (21) 02
NUMBERS
Donations
C U
TA N
EO U
S
Donors
Distributed to end user in another EU country
Received from a tissue establishment (transport) in
another EU country
Application procedures
CARDIAC TISSUE
Pericardium
Distributed to end user in the country
HV, aortic
Pericardium
Other heart tissues
Acellular dermal matrix
Applications for other treatments (only use if the application does not fit into one of the above categories)
Skin cm2 cm2
Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
Sent to a tissue establishment (transport) in another EU country
Skin cm2 Acellular dermal matrix cm2 Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
Applications for burns/wound healing # of applications (one surgical procedure, regardless of the # of grafts used) Applications for reconstructive surgery # of applications (one surgical procedure, regardless of the # of grafts used)
# of applications (one surgical procedure, regardless of the # of grafts used)
Imports (non EU)
Skin cm2 Acellular dermal matrix cm2 Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
Skin cm2 Acellular dermal matrix cm2 Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
Exports (non EU)
Skin cm2 Acellular dermal matrix cm2 Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
# of containers Other heart tissues # of containers
Releases for clinical application, whether distributed or not
HV, aortic # of HV HV, pulmonary # of HV HV, aortic decellularised # of HV HV, pulmonary decellularised # of HV
UNITS/EXPLANATIONS
Living donors # of living cardiac tissue donors at national level Deceased donors # of deceased cardiac tissue donors at national level Cardiac tissue donations # of donation events from one donor, regardless of the number of tissues obtained
Non-valved patches and conduits # of containers
# of containers Other heart tissues # of containers HV, aortic # of HV HV, pulmonary # of HV
Pericardium # of containers
# of HV HV, pulmonary # of HV HV, aortic decellularised # of HV HV, pulmonary decellularised # of HV Non-valved patches and conduits # of containers
# of containers
Distributed to end user in another EU country
HV, aortic decellularised # of HV HV, pulmonary decellularised # of HV Non-valved patches and conduits # of containers
CU 18 CU 19 CU 20 CU 21 CU 22 CU 23 CU 24 CU 25 CU 26
CU 12 CU 13 CU 14 CU 15 CU 16 CU 17
CA 2 CA 3 CA 4 CA 5 CA 6 CA 7 CA 8 CA 9
CA 10
CU 27 CU 28 CU 29 CU 30 CU 31 CU 32 CU 33 CU 34
CA 1
CA 20 CA 21 CA 22 CA 23 CA 24
CA 11 CA 12 CA 13 CA 14 CA 15 CA 16 CA 17 CA 18 CA 19
PA/PH/TO (21) 02 4 of 14 Work Package 7 / GA 2018 53 01
NUMBERS
Donations
Donors
Received from a tissue establishment (transport) in
another EU country Non-valved patches and conduits
HV, aortic
C A
R D
IA C
# of HV HV, pulmonary decellularised # of HV Non-valved patches and conduits # of containers Pericardium # of containers
# of HV
Sent to a tissue establishment (transport) in another EU country
HV, aortic # of HV HV, pulmonary # of HV HV, aortic decellularised
# of containers Pericardium # of containers Other heart tissues # of containers
Other heart tissues # of containers
Exports (non EU)
HV, aortic # of HV HV, pulmonary # of HV HV, aortic decellularised # of HV HV, pulmonary decellularised # of HV Non-valved patches and conduits # of containers Pericardium # of containers Other heart tissues # of containers
HV, aortic # of HV HV, pulmonary # of HV HV, aortic decellularised # of HV HV, pulmonary decellularised
# HV HV, pulmonary # HV
Pericardium # of containers Other heart tissues # of containers
Application procedures Applications for HV replacement # of applications (one surgical procedure, regardless of the # of grafts used) Applications for cardiac reconstruction # of applications (one surgical procedure, regardless of the # of grafts used) Applications for other treatments (only use if the application does not fit into one of the above categories) # of applications (one surgical procedure, regardless of the # of grafts used)
HV, aortic decellularised # HV HV, pulmonary decellularised # HV Non-valved patches and conduits # of containers
Distributed to end user in the country
Vessels, arteries # of containers
Vessels, veins # of containers
Distributed to end user in another EU country
Vessels, arteries # of containers
Vessels, veins # of containers
VESSELS UNITS/EXPLANATIONS
Living donors # of living vessel donors at national level
Deceased donors # of deceased vessel donors at national level
Vessel donations # of donation events from one donor, regardless of the number of tissues obtained
Releases for clinical application, whether distributed or not
Vessels, arteries # of containers
Vessels, veins # of containers
Received from a tissue establishment (transport) in
another EU country
Vessels, arteries # of containers
Vessels, veins # of containers
Exports (non EU)
Vessels, arteries # of containers
Vessels, veins # of containers
Sent to a tissue establishment (transport) in another EU country
Vessels, arteries # of containers
Vessels, veins # of containers
VE SS
EL S
CA 25 CA 26 CA 27 CA 28
CA 38 CA 39 CA 40 CA 41 CA 42 CA 43 CA 44 CA 45 CA 46
CA 29 CA 30 CA 31 CA 32 CA 33 CA 34 CA 35 CA 36 CA 37
VE 1
VE 2
VE 3
VE 4
VE 5
VE 6
VE 7
VE 8
VE 9
CA 47 CA 48 CA 49 CA 50 CA 51 CA 52 CA 53 CA 54 CA 55
VE 13
VE 14
VE 15
VE 10
VE 11
VE 12
Work Package 7 / GA 2018 53 01 5 of 14 PA/PH/TO (21) 02
Imports (non EU)
Application procedures
NUMBERS
Donations
Donors
Whole or part of structural/supporting bone
Whole or part of structural/supporting bone
Applications # of applications (one surgical procedure, regardless of the # of grafts used)
Imports (non EU)
Vessels, arteries # of containers
Vessels, veins # of containers
UNITS/EXPLANATIONS
Living donors # of living musculoskeletal tissue donors at national level (including for autologous use of cranial bone and cartilage)
Deceased donors # of deceased musculoskeletal tissue donors at national level
Musculoskeletal tissue donations # of donation events from one donor, regardless of the number of tissues obtained (including for autologous use of cranial bone and cartilage)
Releases for clinical application, whether distributed or not
Whole or part of structural/supporting bone # of pieces Tendons (including with bony attachments)/ligaments/fascia # of pieces Osteochondral grafts # of pieces Bone filling material (excluding femoral heads) # of containers
Demineralised bone matrix (including combined with a carrier) # of containers Meniscus # of pieces Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage) # of containers
MUSCULOSKELETAL TISSUE
# of pieces Tendons (including with bony attachments)/ligaments/fascia # of pieces
Demineralised bone matrix (including combined with a carrier) # of containers Meniscus # of pieces
Whole or part of structural/supporting bone # of pieces Tendons (including with bony attachments)/ligaments/fascia # of pieces Osteochondral grafts
Osteochondral grafts # of pieces Bone filling material (excluding femoral heads) # of containers
# of containers
# of pieces Tendons (including with bony attachments)/ligaments/fascia # of pieces Osteochondral grafts # of pieces Bone filling material (excluding femoral heads) # of containers
# of pieces Tendons (including with bony attachments)/ligaments/fascia # of pieces Osteochondral grafts # of pieces Bone filling material (excluding femoral heads)
Demineralised bone matrix (including combined with a carrier)
# of pieces Bone filling material (excluding femoral heads) # of containers
# of containers Demineralised bone matrix (including combined with a carrier) # of containers
# of containers
# of containers Meniscus # of pieces
# of containers
# of containers
# of containers
# of containers
# of containers
Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage)
Distributed to end user in the country
Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage)
Distributed to end user in another EU country
Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage)
Sent to a tissue establishment (transport) in another EU country
Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage)
Received from a tissue establishment (transport) in
another EU country # of containers
# of containers Demineralised bone matrix (including combined with a carrier) # of containers Meniscus # of pieces
Meniscus # of pieces
Whole or part of structural/supporting bone
M U
SK U
LO SK
EL ET
A L
MU 1
MU 2
MU 3
MU 4 MU 5 MU 6 MU 7 MU 8 MU 9
MU 10 MU 11 MU 12 MU 13 MU 14
MU 23
VE 16
VE 17
VE 18
MU 36 MU 37 MU 38 MU 39 MU 40 MU 41
MU 24 MU 25 MU 26 MU 27 MU 28 MU 29 MU 30 MU 31 MU 32
MU 15 MU 16 MU 17 MU 18 MU 19 MU 20 MU 21 MU 22
Femoral heads
Femoral heads
Femoral heads
Femoral heads
Femoral heads
MU 42 MU 43
MU 33 MU 34 MU 35
PA/PH/TO (21) 02 6 of 14 Work Package 7 / GA 2018 53 01
NUMBERS
Donations
Application procedures
NUMBERS
Donations
Application procedures
Donors
N EU
R O
N A
L
Donors
Bone filling material (excluding femoral heads)
Bone filling material (excluding femoral heads)
Meniscus
NEURONAL TISSUE
Sent to a tissue establishment (transport) in another EU country Nerves
# of applications (one surgical procedure, regardless of the # of grafts used) Application for dental procedures # of applications (one surgical procedure, regardless of the # of grafts used) Applications for other treatments (only use if the application does not fit into one of the above categories) # of applications (one surgical procedure, regardless of the # of grafts used)
# of containers # of containers
Demineralised bone matrix (including combined with a carrier) # of containers
Application for orthopaedic/maxillofacial surgery
# of pieces
Demineralised bone matrix (including combined with a carrier) # of containers Meniscus # of pieces
Whole or part of structural/supporting bone # of pieces Tendons (including with bony attachments)/ligaments/fascia # of pieces Osteochondral grafts
Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage)
Tendons (including with bony attachments)/ligaments/fascia # of pieces Osteochondral grafts # of pieces
Whole or part of structural/supporting bone # of pieces
# of containers
Releases for clinical application, whether distributed or not Nerves # of containers
Distributed to end user in the country Nerves # of containers
UNITS/EXPLANATIONS
Living donors # of living neuronal tissue donors at national level
Deceased donors # of deceased neuronal tissue donors at national level
Nerve donations # of donation events from one donor, regardless of the number of tissues obtained
Distributed to end user in another EU country Nerves # of containers
ADIPOSE TISSUE UNITS/EXPLANATIONS
Living donors # of living adipose tissue donors at national level
Deceased donors # of deceased adipose tissue donors at national level
Adipose tissue donations # of donation events from one donor, regardless of the number of tissues obtained
# of containers
Applications # of applications (one surgical procedure, regardless of the # of grafts used)
Received from a tissue establishment (transport) in
another EU country Nerves # of containers
Exports (non EU) Nerves # of containers
Imports (non EU) Nerves
Exports (non EU)
Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage)
Imports (non EU)
# of containers
# of containers # of pieces
# of containers # of containers
NE 4
NE 5
NE 6
NE 7
NE 8
NE 9
NE 10
NE 1
NE 2
NE 3
MU 62
MU 60 MU 61
MU 59
NE 11
AD 1
AD 2
AD 3
Femoral heads
Femoral heads
MU 51 MU 52 MU 53 MU 54 MU 55 MU 56 MU 57 MU 58
MU 44 MU 45 MU 46 MU 47 MU 48 MU 49 MU 50
Work Package 7 / GA 2018 53 01 7 of 14 PA/PH/TO (21) 02
NUMBERS
Donations
Application procedures
NUMBERS
Donations
Donors
A D
IP O
SE
Donors
PA N
C R
EA TI
C Releases for clinical application,
whether distributed or not
Received from a tissue establishment (transport) in
another EU country
Imports (non EU)
PANCREATIC TISSUE
Sent to a tissue establishment (transport) in another EU country Pancreatic islets
Imports (non EU) Pancreatic islets
HEPATIC TISSUE
Adipose tissue # of containers
Exports (non EU) Adipose tissue # of containers
Distributed to end user in another EU country Adipose tissue # of containers
Sent to a tissue establishment (transport) in another EU country Adipose tissue # of containers
Adipose tissue # of containers
Distributed to end user in the country Adipose tissue # of containers
UNITS/EXPLANATIONS
Living donors # of living pancreatic tissue donors at national level
Deceased donors # of deceased pancreatic tissue donors at national level
Pancreatic tissue donations # of donation events from one donor, regardless of the number of tissues obtained
Distributed to end user in another EU country Pancreatic islets # of containers
Adipose tissue # of containers
Application procedures
Applications for reconstructive surgery # of applications (one surgical procedure, regardless of the # of grafts used)
Applications for aesthetic surgery # of applications (one surgical procedure, regardless of the # of grafts used)
Applications for other treatments (only use if the application does not fit into one of the above categories) # of applications (one surgical procedure, regardless of the # of grafts used)
# of containers
Applications # of applications (one single procedure, regardless of the # of grafts used)
Received from a tissue establishment (transport) in
another EU country Pancreatic islets # of containers
Exports (non EU) Pancreatic islets # of containers
# of containers
Releases for clinical application, whether distributed or not Pancreatic islets # of containers
Distributed to end user in the country Pancreatic islets # of containers
UNITS/EXPLANATIONS
Living donors # of living hepatic tissue donors at national level
Deceased donors # of deceased hepatic tissue donors at national level
Hepatic tissue donations # of donation events from one donor, regardless of the number of tissues obtained
PA 5
PA 6
PA 7
PA 8
PA 9
PA 10
PA 11
AD 7
AD 8
AD 9
AD 10
AD 11
AD 12
AD 13
PA 1
PA 2
AD 4
AD 5
AD 6
HE 1
HE 2
HE 3
PA 3
PA 4
PA/PH/TO (21) 02 8 of 14 Work Package 7 / GA 2018 53 01
Application procedures
NUMBERS
Donations
Application procedures
PA R
A TH
YR O
ID H
EP A
TI C
Sent to a tissue establishment (transport) in another EU country Hepatocytes
Imports (non EU) Hepatocytes
PARATHYROID TISSUE
Received from a tissue establishment (transport) in
another EU country Hepatocytes # of containers
Distributed to end user in another EU country Hepatocytes # of containers
Releases for clinical application, whether distributed or not Hepatocytes # of containers
Distributed to end user in the country Hepatocytes # of containers
Applications # of applications (one surgical procedure, regardless of the # of grafts used)
Received from a tissue establishment (transport) in
another EU country Parathyroid tissue # of containers
Exports (non EU) Parathyroid tissue # of containers
Exports (non EU) Hepatocytes # of containers
# of containers
Parathyroid tissue # of containers
Imports (non EU) Parathyroid tissue # of containers
Distributed to end user in another EU country Parathyroid tissue # of containers
Sent to a tissue establishment (transport) in another EU country Parathyroid tissue
UNITS/EXPLANATIONS
Living donors # of living parathyroid tissue donors at national level
Deceased donors # of deceased parathyroid tissue donors at national level
Parathyroid tissue donations # of donation events from one donor, regardless of the number of tissues obtained
Donors
# of containers
Releases for clinical application, whether distributed or not
Distributed to end user in the country Parathyroid tissue # of containers
# of containers
Applications # of applications (one procedure, regardless of the # of grafts used)
PR 8
PR 9
PR 10
PR 11
HE 10
HE 11
PR 1
PR 2
PR 3
PR 4
PR 5
PR 6
PR 7
HE 4
HE 5
HE 6
HE 7
HE 8
HE 9
Work Package 7 / GA 2018 53 01 9 of 14 PA/PH/TO (21) 02
COUNTRY YEAR
Registered at 01/01 00:00
IMPORT EXPORT
Nationally From EU countries To EU countries From non-EU
countries To non-EU countries
Paediatric (<18 yr.) Adult
RELEASED FOR CLINICAL APPLICATION AUTOLOGOUS
Related donor Unrelated registry donor
D O
N A
TI O
N C
EN TR
E
TE a 5 TE a 6 TE a 7
DC a 4 DC a 5 DC a 6
TE a 1 TE a 2
SS b 4 SS b 5
DC a 1 DC a 2 DC a 3
SS a 1 SS a 2
SS b 1 SS b 2 SS b 3
HAEMATOPOIETIC CELLS ACTIVITY DATA
Unrelated registry donor
HPC from peripheral blood for transplantation Peripheral blood mononuclear cells for transplant support (e.g. donor lymphocytes for infusion) Peripheral blood mononuclear cells for other purposes, excluding ATMP (e.g. production of CAR-T cells, NK cells)
HPC from peripheral blood for transplantation Peripheral blood mononuclear cells for transplant support (e.g. donor lymphocytes for infusion) Peripheral blood mononuclear cells for other purposes, excluding ATMP (e.g. production of CAR-T cells, NK cells) HPC from cord blood for transplantation
HPC from bone marrow for transplantation
AUTOLOGOUS
SE LF
-S U
FF IC
IE N
C Y
DISTRIBUTED
Related donor ALLOGENEIC
TI SS
U E
ES TA
B LI
SH EM
EN T ALLOGENEIC
Other cells (e.g. bone marrow for other purposes), excluding ATMP
TE a 3 TE a 4
DONATION/COLLECTION
POTENTIAL FOR ALLOGENEIC DONATION
# of registered and typed HPC donors # of registered and typed cord blood units available for transplantation of unrelated patients
DISTRIBUTION AND EXCHANGE
# of unrelated (unit: Cell product from one donor, regardless of the number of donations/containers)
HPC from bone marrow for transplantation
HPC from peripheral blood for transplantation Peripheral blood mononuclear cells for transplant support (e.g. donor lymphocytes for infusion) Peripheral blood mononuclear cells for other purposes, excluding ATMP (e.g. production of CAR-T cells, NK cells) HPC from cord blood for transplantation Cord blood for other purposes, excluding ATMP (e.g. production of NK cells, mesenchymals)
HPC from cord blood Other cells (e.g. bone marrow for other purposes), excluding ATMP
# of donations (unit: Cell product collected from one donor in one donation procedure - may encompass more than one apheresis session)
# released for clinical application, whether distributed or not (unit: Cell product collected from one donor in one donation procedure - may encompass more than one apheresis session) HPC from bone marrow for transplantation
PA/PH/TO (21) 02 10 of 14 Work Package 7 / GA 2018 53 01
AUTOLOGOUS
Related donor Unrelated registry donor
AUTOLOGOUS
Related donor Unrelated registry donor
TC b 3 TC b 4 TC b 5
TC a 3 TC a 4 TC a 5
TC b 1 TC b 2
TC a 1 TC a 2
ALLOGENEIC
TR A
N SP
LA N
T C
EN TR
ES
OTHER PROCEDURES ASSOCIATED WITH CLINICAL APPLICATION
Peripheral blood mononuclear cells for other purposes (e.g. NK cells, Tregs, virus-specific cells), excluding ATMP Other cells for other purposes, excluding ATMP
# of procedures (unit: One application with cells obtained from one or more donors)
# of transplants (unit: One transplant procedure with cells obtained from one or more donors) # of recipients (unit: One patient who had at least one transplant procedure during the year concerned) HPC from bone marrow for transplantation HPC from peripheral blood for transplantation
TRANSPLANT PROCEDURES ASSOCIATED WITH CLINICAL APPLICATION
HPC from cord blood for transplantation
# of recipients (unit: One patient who had at least one procedure during the year concerned) Peripheral blood mononuclear cells for transplant support (e.g. donor lymphocytes for infusion)
ALLOGENEIC
Work Package 7 / GA 2018 53 01 11 of 14 PA/PH/TO (21) 02
COUNTRY YEAR
IUI IVF/ICSI Frozen/cryo embryo transfers (FET)
# of couples treated
# of treatment cycles without stimulation
# of treatment cycles with stimulation
PARTNER GAMETES/EMBRYOS Numbers (regardless of treatment type)
# of oocyte retrievals
# of oocytes retrieved
# of oocytes cryopreserved
# of sperm collections (including MESA, PESA and TESE)
# of sperm units cryopreserved
# of embryos cryopreserved
# of embryo transfers (fresh or cryo)
# of embryos transferred (fresh or cryo)
# of embryos transferred (fresh or cryo) from donated sperm and partner oocytes # of embryos transferred (fresh or cryo) from donated oocytes and partner sperm
IMPORT EXPORT From other EU countries To other EU countries From non-EU countries To non-EU countries
# of oocytes
# of sperm units
# of embryos
# of ovarian tissues
# of testicular tissues (including MESA, PESA and TESE)
Treatment type IUI IVF/ICSI (fresh or cryo)
# of deliveries
# of live born children
# of oocytes
# of straws/vials
# of embryos
# of procedures, regardless of the number of embryos transferred
# of embryos
# of embryos
# of embryos
PA b 8
PA b 9
PA c 5
MAR ACTIVITY DATA
PA d 1
PA d 2
PA b 10
PA c 1
PA c 2
PA c 3
PA c 4
# of cycles with ovarian stimulation (excludes hormone substituted cycles) that ended up with one of the interventions
# of couples that had at least one treatment cycle intervention (IUI, IVF/ICSI and/or FET) completed
UNITS/EXPLANATIONS
# of cycles without ovarian stimulation (includes hormone substituted cycles) that ended up with one of the interventions
MAR PARTNER ACTIVITIES
PA a 1
PA a 2
PA a 3
PA b 1
PA b 2
PA b 3
PA b 4
# of retrieval procedures where at least one oocyte was retrieved
# of oocytes retrieved in total
# oocytes cryopreserved in total
# of collections, regardless of number of straws and method of collection used
UNITS/EXPLANATIONS
# of vials/containers
TRANSPORT/DISTRIBUTION
PA R
TN ER
P R
O C
ED U
R ES
Treatment type
DELIVERIES AND LIVE BORN CHILDREN (born during the reporting year regardless of when conceived) UNITS/EXPLANATIONS
# of deliveries regardless of the number of children born (including stillborn)
# of infants with any vital signs
DISTRIBUTION AND EXCHANGE OF PARTNER GAMETES/TISSUES/EMBRYOS (ACCESS TO CARE)
# of vials/containers
# of straws/vials
# of embryos
UNITS/EXPLANATIONS
PA b 5
PA b 6
PA b 7
PA/PH/TO (21) 02 12 of 14 Work Package 7 / GA 2018 53 01
NON-PARTNER GAMETES/EMBRYOS Numbers (regardless of treatment type)
# of oocyte donors for dedicated and split donation cycles
# of oocyte donors of supernumerary oocytes (from partner procedures)
# of oocyte retrievals intended for donation (dedicated or split)
# of oocytes donated (dedicated, split or supernumerary)
# of oocytes cryopreserved (dedicated, split or supernumerary)
# of sperm donors
# of sperm collections
# of sperm units cryopreserved
# of embryos donated
IMPORT EXPORT From other EU countries To other EU countries From non-EU countries To non-EU countries
# of sperm units
# of donated embryos
Treatment type IUI IVF/ICSI
# of recipients
# of treatment cycles with donated sperm
# of partner oocyte retrievals
# of embryos cryopreserved
# of embryo transfers (fresh or cryo)
# of embryos transferred (fresh or cryo)
MAR with non partner OOCYTE donation IVF/ICSI
# of recipients
# of treatment cycles with donated oocytes
# of partner sperm collections
# of embryos cryopreserved
# of embryo transfers (fresh or cryo)
# of embryos transferred (fresh or cryo)
MAR with non partner OOCYTES AND SPERM donation (double donation) IVF/ICSI
# of recipients
# of treatment cycles with donated oocytes and sperm
# of embryos cryopreserved
NP a 3
NP a 4
NP a 5
NP a 6
NP a 7
NP a 8
NP a 9
NP b 1
NP b 2
# of retrieval procedures where at least one oocyte was retrieved
# women who underwent at least one embryo transfer involving donated oocytes (in the reporting country)
NP c 1
NP c 2
NP c 3
NP d 5
NP e 3
UNITS/EXPLANATIONS
# of straws/vials
NP d 3
MAR with non partner SPERM donation
DISTRIBUTION AND EXCHANGE OF NON-PARTNER GAMETES/EMBRYOS (COMMERCIALISATION)
# of embryos (cryopreserved) from donated oocytes
# of procedures involving donated oocytes, regardless of the number of embryos transferred
# of embryos (transferred) from donated oocytesNP d 6
NP e 1
NP e 2
# of cycles, with or without ovarian stimulation, where donated sperm was used
# of embryos (cryopreserved) from donated sperm
# of embryos (transferred) from donated sperm
# of transfer procedures involving donated sperm, regardless of the number of embryos transferred
UNITS/EXPLANATIONS
UNITS/EXPLANATIONS
NP d 4
NP c 4
NP c 5
NP c 6
NP d 1
NP d 2
NP a 1
NP a 2
N O
N -P
A R
TN ER
P R
O C
ED U
R ES
TRANSPORT/DISTRIBUTION
# of donors of supernumerary oocytes from partner procedures, regardless of the number of donations
# of straws/vials
UNITS/EXPLANATIONS
# of donors (recruited for the specific purpose of donation), regardless of the number of donations
# women who underwent at least one embryo transfer involving donated oocytes and sperm (in the reporting country)
# of embryos (cryopreserved ) from donated oocytes and sperm
# of cycles, stimulated or non-stimulated, where donated oocytes were used
UNITS/EXPLANATIONS
# of cycles, stimulated or non-stimulated, where donated oocytes and sperm were used
# of collections, regardless of the number of straws
# of embryos
# women who underwent IUI and/or an embryo transfer involving donated sperm (in the reporting country)
# of collections, regardless of the number of straws
# of embryos (supernumerary after partner and non-partner treatments)
# of donors who provided at least one sample during the year
# of oocytes
# of oocytes
# of retrieval procedures where at least one oocyte was retrieved
Work Package 7 / GA 2018 53 01 13 of 14 PA/PH/TO (21) 02
# of embryo transfers (fresh or cryo)
# of embryos transferred (fresh or cryo)
MAR with EMBRYO donation (supernumerary from partner or non-partner treatments) IVF/ICSI
# of recipients
# of treatment cycles with donated embryos
# of embryo transfers (fresh or cryo)
# of embryos transferred (fresh or cryo)
Treatment type IUI IVF/ICSI (fresh or cryo)
# of deliveries
# of live born children
FERTILITY PRESERVATION Numbers
# of patients who underwent one or more oocyte retrievals
# of oocyte retrieval procedures
# of patients who underwent one or more sperm collections (including MESA, PESA and TESE) # of sperm collection procedures (including MESA, PESA and TESE)
# of patients who underwent an ovarian tissue collection
# of ovarian tissue collection procedures
# of patients who underwent a collection of immature testicular tissue
# of immature testicular tissue collection procedures
# of patients who underwent an ovarian tissue transplantation
NP f 2
NP e 4
NP e 5
NP f 1
FP a 6
FP a 7
FP a 8
FP a 9
FP a 1
FP a 2
FP a 3
FP a 4
FP a 5
FE R
TI LI
TY P
R ES
ER VA
TI O
N
DELIVERIES AND LIVE BORN CHILDREN (during the reporting year regardless of when conceived)
NP g 1
NP g 2
# of patients who underwent an ovarian tissue transplantation, regardless of the number of tissue fragments transplanted
# of patients who underwent a collection procedure of immature testicular tissue (i.e. not containing sperm), regardless of the amount of tissue collected
# of patients who underwent an ovarian tissue collection procedure, regardless of the amount of tissue collected
# of immature testicular tissue collection procedures, regardless of the amount of tissue collected
# of sperm collection procedures (including MESA, PESA and TESE with mature sperm extracted), regardless of the amount of straws/vials obtained
# of ovarian tissue collection procedures, regardless of the amount of tissue collected
# of oocyte retrieval procedures, regardless of the number of oocytes retrieved
# of patients who underwent at least one sperm collection procedure (including MESA, PESA and TESE with mature sperm extracted), regardless of the amount of straws/vials obtained
# of patients who underwent at least one oocyte retrieval procedure, regardless of the number of oocytes retrieved
UNITS/EXPLANATIONS
NP f 3
NP f 4
# of infants with any vital signs
# of procedures involving donated supernumerary embryos regardless of the number of embryos transferred
# of embryos (transferred) from donated supernumerary embryos
# women who underwent at least one embryo transfer involving donated supernumerary embryos (in the reporting country)
UNITS/EXPLANATIONS
# of deliveries, regardless of the number of children born (including stillborn)
# of cycles, stimulated or non-stimulated, where donated supernumerary embryos were used
UNITS/EXPLANATIONS
# of embryos (transferred) from donated oocytes and sperm
# of procedures involving donated oocytes and sperm, regardless of the number of embryos transferred
PA/PH/TO (21) 02 14 of 14 Work Package 7 / GA 2018 53 01
COUNTRY Year
NUMBERS
NUMBERS
Donations
# of containers
Sclera # of containers
Releases for clinical application, whether distributed or not
Cornea, full thickness (high endothelial cell density)
Other ocular
Distributed to end user in the country
Cornea, full thickness (high endothelial cell density) # of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2 Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment) # of corneas Sclera # of containers Other ocular # of containers
REPLACEMENT TISSUES ACTIVITY DATA
OCULAR TISSUE UNITS/EXPLANATIONS
# of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2
O C
U LA
R
Donors
DONORS (COLLECTED AT NATIONAL LEVEL)
Deceased donors Living donors
Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment) # of corneas Sclera # of containers
Living donors # of living ocular tissue/cell donors at national level Deceased donors # of deceased ocular tissue/cell donors at national level Ocular tissue donations # of donation events from one donor, may include 1 or 2 eyes/corneas
Distributed to end user in another EU country
Cornea, full thickness (high endothelial cell density) # of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2 Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment) # of corneas
Received from a tissue establishment (transport) in
another EU country
Cornea, full thickness (high endothelial cell density) # of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2
Sclera # of containers Other ocular # of containers
Sent to a tissue establishment (transport) in another EU country
Cornea, full thickness (high endothelial cell density) # of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2 Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment)
Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment) # of corneas
Other ocular # of containers
# of corneas Sclera # of containers Other ocular # of containers
# of containers
Imports (non EU)
Cornea, full thickness (high endothelial cell density) # of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2 Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment) # of corneas Sclera # of containers
Exports (non EU)
Cornea, full thickness (high endothelial cell density) # of corneas with endothelial cell density ≥ 2000 cells per mm2 Cornea, full thickness (low endothelial cell density) # of corneas with endothelial cell density < 2000 cells per mm2 Cornea for Endothelial Keratoplasty (precut/peeled in the Tissue Establishment) # of corneas Sclera # of containers Other ocular
Other ocular # of containers
# of deceased tissue/cell donors at national level # of living tissue/cell donors at national level
UNITS/EXPLANATIONS
OC 2 OC 1
OC 3 OC 4 OC 5 OC 6 OC 7 OC 8
OC 18 OC 19 OC 20 OC 21 OC 22 OC 23 OC 24 OC 25 OC 26
OC 9 OC 10 OC 11 OC 12 OC 13 OC 14 OC 15 OC 16 OC 17
OC 36 OC 37 OC 38
OC 27 OC 28 OC 29 OC 30 OC 31 OC 32 OC 33 OC 34 OC 35
DD LD
PA/PH/TO (21) 02 2 of 14 Work Package 7 / GA 2018 53 01
NUMBERS
Donations
NUMBERS
Donations
Amniotic membrane eyedrops # of batches prepared for a single patient
Amniotic membrane eyedrops # of batches prepared for a single patient
Amniotic membrane eyedrops # of batches prepared for a single patient
Amniotic membrane eyedrops # of batches prepared for a single patient
Amniotic membrane # of containers
Other placental # of containers # of containers
Other placental # of containers Amniotic membrane # of containers
Other placental # of containers
PL A
C EN
TA L
Donors
Donors
Releases for clinical application, whether distributed or not
Distributed to end user in the country
Sent to a tissue establishment (transport) in another EU country
Exports (non EU)
Releases for clinical application, whether distributed or not
Amniotic membrane
Distributed to end user in another EU country
Amniotic membrane
Amniotic membrane
Living donors
Skin
Deceased donors # of deceased placental tissue donors at national level
Application procedures
Applications for Penetrating Keratoplasty # of applications (one surgical procedure, regardless of the # of grafts used) Applications for Anterior Lamellar Keratoplasty # of applications (one surgical procedure, regardless of the # of grafts used) Applications for Endothelial Keratoplasty # of applications (one surgical procedure, regardless of the # of grafts used)
# of containers
Other placental # of containers
Imports (non EU)
Amniotic membrane # of containers
Other placental # of containers
Amniotic membrane eyedrops # of batches prepared for a single patient
Amniotic membrane eyedrops # of batches prepared for a single patient
Applications for scleral reconstruction
Placental membrane donations # of donation events from one delivery, including multiple births
Amniotic membrane eyedrops # of batches prepared for a single patient
Received from a tissue establishment (transport) in
another EU country
Amniotic membrane # of containers
Other placental # of containers
# of containers
Other placental # of containers
# of applications (one surgical procedure, regardless of the # of grafts used) Applications for other ocular treatments (only use if the application does not fit into one of the above categories) # of applications (one surgical procedure, regardless of the # of grafts used)
PLACENTAL TISSUE UNITS/EXPLANATIONS
Living donors # of living placental tissue donors at national level
# of living cutaneous tissue donors at national level Deceased donors # of deceased cutaneous tissue donors at national level Skin donations # of donation events from one donor, regardless of the number of tissues obtained
Amniotic membrane applications for ocular treatment (excluding amniotic eye drops) # of applications (one surgical procedure, regardless of the # of grafts used)
Amniotic membrane applications for other treatments # of applications (one surgical procedure, regardless of the # of grafts used)
CUTANEOUS TISSUE UNITS/EXPLANATIONS
Amniotic membrane applications for non-ocular burn/wound healing # of applications (one surgical procedure, regardless of the # of grafts used) Amniotic membrane applications for ocular treatment (amniotic eye drops) # of batches prepared for a single patient
Other placental tissue applications (only use if the application does not fit into one of the above categories) # of applications (one surgical procedure, regardless of the # of grafts used)
Application procedures
cm2 Acellular dermal matrix cm2 Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
Distributed to end user in the country
Skin cm2 Acellular dermal matrix cm2 Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
OC 39 OC 40 OC 41 OC 42 OC 43
PL 1
PL 11 PL 12 PL 13 PL 14 PL 15 PL 16 PL 17 PL 18 PL 19
PL 2 PL 3 PL 4 PL 5 PL 6 PL 7 PL 8 PL 9
PL 10
PL 29
CU 1 CU 2 CU 3 CU 4 CU 5 CU 6 CU 7 CU 8
PL 20 PL 21 PL 22 PL 23 PL 24 PL 25 PL 26 PL 27 PL 28
CU 9 CU 10 CU 11
Work Package 7 / GA 2018 53 01 3 of 14 PA/PH/TO (21) 02
NUMBERS
Donations
C U
TA N
EO U
S
Donors
Distributed to end user in another EU country
Received from a tissue establishment (transport) in
another EU country
Application procedures
CARDIAC TISSUE
Pericardium
Distributed to end user in the country
HV, aortic
Pericardium
Other heart tissues
Acellular dermal matrix
Applications for other treatments (only use if the application does not fit into one of the above categories)
Skin cm2 cm2
Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
Sent to a tissue establishment (transport) in another EU country
Skin cm2 Acellular dermal matrix cm2 Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
Applications for burns/wound healing # of applications (one surgical procedure, regardless of the # of grafts used) Applications for reconstructive surgery # of applications (one surgical procedure, regardless of the # of grafts used)
# of applications (one surgical procedure, regardless of the # of grafts used)
Imports (non EU)
Skin cm2 Acellular dermal matrix cm2 Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
Skin cm2 Acellular dermal matrix cm2 Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
Exports (non EU)
Skin cm2 Acellular dermal matrix cm2 Keratinocytes/melanocytes # of containers Other cutaneous tissues # of containers
# of containers Other heart tissues # of containers
Releases for clinical application, whether distributed or not
HV, aortic # of HV HV, pulmonary # of HV HV, aortic decellularised # of HV HV, pulmonary decellularised # of HV
UNITS/EXPLANATIONS
Living donors # of living cardiac tissue donors at national level Deceased donors # of deceased cardiac tissue donors at national level Cardiac tissue donations # of donation events from one donor, regardless of the number of tissues obtained
Non-valved patches and conduits # of containers
# of containers Other heart tissues # of containers HV, aortic # of HV HV, pulmonary # of HV
Pericardium # of containers
# of HV HV, pulmonary # of HV HV, aortic decellularised # of HV HV, pulmonary decellularised # of HV Non-valved patches and conduits # of containers
# of containers
Distributed to end user in another EU country
HV, aortic decellularised # of HV HV, pulmonary decellularised # of HV Non-valved patches and conduits # of containers
CU 18 CU 19 CU 20 CU 21 CU 22 CU 23 CU 24 CU 25 CU 26
CU 12 CU 13 CU 14 CU 15 CU 16 CU 17
CA 2 CA 3 CA 4 CA 5 CA 6 CA 7 CA 8 CA 9
CA 10
CU 27 CU 28 CU 29 CU 30 CU 31 CU 32 CU 33 CU 34
CA 1
CA 20 CA 21 CA 22 CA 23 CA 24
CA 11 CA 12 CA 13 CA 14 CA 15 CA 16 CA 17 CA 18 CA 19
PA/PH/TO (21) 02 4 of 14 Work Package 7 / GA 2018 53 01
NUMBERS
Donations
Donors
Received from a tissue establishment (transport) in
another EU country Non-valved patches and conduits
HV, aortic
C A
R D
IA C
# of HV HV, pulmonary decellularised # of HV Non-valved patches and conduits # of containers Pericardium # of containers
# of HV
Sent to a tissue establishment (transport) in another EU country
HV, aortic # of HV HV, pulmonary # of HV HV, aortic decellularised
# of containers Pericardium # of containers Other heart tissues # of containers
Other heart tissues # of containers
Exports (non EU)
HV, aortic # of HV HV, pulmonary # of HV HV, aortic decellularised # of HV HV, pulmonary decellularised # of HV Non-valved patches and conduits # of containers Pericardium # of containers Other heart tissues # of containers
HV, aortic # of HV HV, pulmonary # of HV HV, aortic decellularised # of HV HV, pulmonary decellularised
# HV HV, pulmonary # HV
Pericardium # of containers Other heart tissues # of containers
Application procedures Applications for HV replacement # of applications (one surgical procedure, regardless of the # of grafts used) Applications for cardiac reconstruction # of applications (one surgical procedure, regardless of the # of grafts used) Applications for other treatments (only use if the application does not fit into one of the above categories) # of applications (one surgical procedure, regardless of the # of grafts used)
HV, aortic decellularised # HV HV, pulmonary decellularised # HV Non-valved patches and conduits # of containers
Distributed to end user in the country
Vessels, arteries # of containers
Vessels, veins # of containers
Distributed to end user in another EU country
Vessels, arteries # of containers
Vessels, veins # of containers
VESSELS UNITS/EXPLANATIONS
Living donors # of living vessel donors at national level
Deceased donors # of deceased vessel donors at national level
Vessel donations # of donation events from one donor, regardless of the number of tissues obtained
Releases for clinical application, whether distributed or not
Vessels, arteries # of containers
Vessels, veins # of containers
Received from a tissue establishment (transport) in
another EU country
Vessels, arteries # of containers
Vessels, veins # of containers
Exports (non EU)
Vessels, arteries # of containers
Vessels, veins # of containers
Sent to a tissue establishment (transport) in another EU country
Vessels, arteries # of containers
Vessels, veins # of containers
VE SS
EL S
CA 25 CA 26 CA 27 CA 28
CA 38 CA 39 CA 40 CA 41 CA 42 CA 43 CA 44 CA 45 CA 46
CA 29 CA 30 CA 31 CA 32 CA 33 CA 34 CA 35 CA 36 CA 37
VE 1
VE 2
VE 3
VE 4
VE 5
VE 6
VE 7
VE 8
VE 9
CA 47 CA 48 CA 49 CA 50 CA 51 CA 52 CA 53 CA 54 CA 55
VE 13
VE 14
VE 15
VE 10
VE 11
VE 12
Work Package 7 / GA 2018 53 01 5 of 14 PA/PH/TO (21) 02
Imports (non EU)
Application procedures
NUMBERS
Donations
Donors
Whole or part of structural/supporting bone
Whole or part of structural/supporting bone
Applications # of applications (one surgical procedure, regardless of the # of grafts used)
Imports (non EU)
Vessels, arteries # of containers
Vessels, veins # of containers
UNITS/EXPLANATIONS
Living donors # of living musculoskeletal tissue donors at national level (including for autologous use of cranial bone and cartilage)
Deceased donors # of deceased musculoskeletal tissue donors at national level
Musculoskeletal tissue donations # of donation events from one donor, regardless of the number of tissues obtained (including for autologous use of cranial bone and cartilage)
Releases for clinical application, whether distributed or not
Whole or part of structural/supporting bone # of pieces Tendons (including with bony attachments)/ligaments/fascia # of pieces Osteochondral grafts # of pieces Bone filling material (excluding femoral heads) # of containers
Demineralised bone matrix (including combined with a carrier) # of containers Meniscus # of pieces Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage) # of containers
MUSCULOSKELETAL TISSUE
# of pieces Tendons (including with bony attachments)/ligaments/fascia # of pieces
Demineralised bone matrix (including combined with a carrier) # of containers Meniscus # of pieces
Whole or part of structural/supporting bone # of pieces Tendons (including with bony attachments)/ligaments/fascia # of pieces Osteochondral grafts
Osteochondral grafts # of pieces Bone filling material (excluding femoral heads) # of containers
# of containers
# of pieces Tendons (including with bony attachments)/ligaments/fascia # of pieces Osteochondral grafts # of pieces Bone filling material (excluding femoral heads) # of containers
# of pieces Tendons (including with bony attachments)/ligaments/fascia # of pieces Osteochondral grafts # of pieces Bone filling material (excluding femoral heads)
Demineralised bone matrix (including combined with a carrier)
# of pieces Bone filling material (excluding femoral heads) # of containers
# of containers Demineralised bone matrix (including combined with a carrier) # of containers
# of containers
# of containers Meniscus # of pieces
# of containers
# of containers
# of containers
# of containers
# of containers
Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage)
Distributed to end user in the country
Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage)
Distributed to end user in another EU country
Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage)
Sent to a tissue establishment (transport) in another EU country
Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage)
Received from a tissue establishment (transport) in
another EU country # of containers
# of containers Demineralised bone matrix (including combined with a carrier) # of containers Meniscus # of pieces
Meniscus # of pieces
Whole or part of structural/supporting bone
M U
SK U
LO SK
EL ET
A L
MU 1
MU 2
MU 3
MU 4 MU 5 MU 6 MU 7 MU 8 MU 9
MU 10 MU 11 MU 12 MU 13 MU 14
MU 23
VE 16
VE 17
VE 18
MU 36 MU 37 MU 38 MU 39 MU 40 MU 41
MU 24 MU 25 MU 26 MU 27 MU 28 MU 29 MU 30 MU 31 MU 32
MU 15 MU 16 MU 17 MU 18 MU 19 MU 20 MU 21 MU 22
Femoral heads
Femoral heads
Femoral heads
Femoral heads
Femoral heads
MU 42 MU 43
MU 33 MU 34 MU 35
PA/PH/TO (21) 02 6 of 14 Work Package 7 / GA 2018 53 01
NUMBERS
Donations
Application procedures
NUMBERS
Donations
Application procedures
Donors
N EU
R O
N A
L
Donors
Bone filling material (excluding femoral heads)
Bone filling material (excluding femoral heads)
Meniscus
NEURONAL TISSUE
Sent to a tissue establishment (transport) in another EU country Nerves
# of applications (one surgical procedure, regardless of the # of grafts used) Application for dental procedures # of applications (one surgical procedure, regardless of the # of grafts used) Applications for other treatments (only use if the application does not fit into one of the above categories) # of applications (one surgical procedure, regardless of the # of grafts used)
# of containers # of containers
Demineralised bone matrix (including combined with a carrier) # of containers
Application for orthopaedic/maxillofacial surgery
# of pieces
Demineralised bone matrix (including combined with a carrier) # of containers Meniscus # of pieces
Whole or part of structural/supporting bone # of pieces Tendons (including with bony attachments)/ligaments/fascia # of pieces Osteochondral grafts
Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage)
Tendons (including with bony attachments)/ligaments/fascia # of pieces Osteochondral grafts # of pieces
Whole or part of structural/supporting bone # of pieces
# of containers
Releases for clinical application, whether distributed or not Nerves # of containers
Distributed to end user in the country Nerves # of containers
UNITS/EXPLANATIONS
Living donors # of living neuronal tissue donors at national level
Deceased donors # of deceased neuronal tissue donors at national level
Nerve donations # of donation events from one donor, regardless of the number of tissues obtained
Distributed to end user in another EU country Nerves # of containers
ADIPOSE TISSUE UNITS/EXPLANATIONS
Living donors # of living adipose tissue donors at national level
Deceased donors # of deceased adipose tissue donors at national level
Adipose tissue donations # of donation events from one donor, regardless of the number of tissues obtained
# of containers
Applications # of applications (one surgical procedure, regardless of the # of grafts used)
Received from a tissue establishment (transport) in
another EU country Nerves # of containers
Exports (non EU) Nerves # of containers
Imports (non EU) Nerves
Exports (non EU)
Other musculoskeletal (e.g. ear ossicles, cranial bone, cartilage)
Imports (non EU)
# of containers
# of containers # of pieces
# of containers # of containers
NE 4
NE 5
NE 6
NE 7
NE 8
NE 9
NE 10
NE 1
NE 2
NE 3
MU 62
MU 60 MU 61
MU 59
NE 11
AD 1
AD 2
AD 3
Femoral heads
Femoral heads
MU 51 MU 52 MU 53 MU 54 MU 55 MU 56 MU 57 MU 58
MU 44 MU 45 MU 46 MU 47 MU 48 MU 49 MU 50
Work Package 7 / GA 2018 53 01 7 of 14 PA/PH/TO (21) 02
NUMBERS
Donations
Application procedures
NUMBERS
Donations
Donors
A D
IP O
SE
Donors
PA N
C R
EA TI
C Releases for clinical application,
whether distributed or not
Received from a tissue establishment (transport) in
another EU country
Imports (non EU)
PANCREATIC TISSUE
Sent to a tissue establishment (transport) in another EU country Pancreatic islets
Imports (non EU) Pancreatic islets
HEPATIC TISSUE
Adipose tissue # of containers
Exports (non EU) Adipose tissue # of containers
Distributed to end user in another EU country Adipose tissue # of containers
Sent to a tissue establishment (transport) in another EU country Adipose tissue # of containers
Adipose tissue # of containers
Distributed to end user in the country Adipose tissue # of containers
UNITS/EXPLANATIONS
Living donors # of living pancreatic tissue donors at national level
Deceased donors # of deceased pancreatic tissue donors at national level
Pancreatic tissue donations # of donation events from one donor, regardless of the number of tissues obtained
Distributed to end user in another EU country Pancreatic islets # of containers
Adipose tissue # of containers
Application procedures
Applications for reconstructive surgery # of applications (one surgical procedure, regardless of the # of grafts used)
Applications for aesthetic surgery # of applications (one surgical procedure, regardless of the # of grafts used)
Applications for other treatments (only use if the application does not fit into one of the above categories) # of applications (one surgical procedure, regardless of the # of grafts used)
# of containers
Applications # of applications (one single procedure, regardless of the # of grafts used)
Received from a tissue establishment (transport) in
another EU country Pancreatic islets # of containers
Exports (non EU) Pancreatic islets # of containers
# of containers
Releases for clinical application, whether distributed or not Pancreatic islets # of containers
Distributed to end user in the country Pancreatic islets # of containers
UNITS/EXPLANATIONS
Living donors # of living hepatic tissue donors at national level
Deceased donors # of deceased hepatic tissue donors at national level
Hepatic tissue donations # of donation events from one donor, regardless of the number of tissues obtained
PA 5
PA 6
PA 7
PA 8
PA 9
PA 10
PA 11
AD 7
AD 8
AD 9
AD 10
AD 11
AD 12
AD 13
PA 1
PA 2
AD 4
AD 5
AD 6
HE 1
HE 2
HE 3
PA 3
PA 4
PA/PH/TO (21) 02 8 of 14 Work Package 7 / GA 2018 53 01
Application procedures
NUMBERS
Donations
Application procedures
PA R
A TH
YR O
ID H
EP A
TI C
Sent to a tissue establishment (transport) in another EU country Hepatocytes
Imports (non EU) Hepatocytes
PARATHYROID TISSUE
Received from a tissue establishment (transport) in
another EU country Hepatocytes # of containers
Distributed to end user in another EU country Hepatocytes # of containers
Releases for clinical application, whether distributed or not Hepatocytes # of containers
Distributed to end user in the country Hepatocytes # of containers
Applications # of applications (one surgical procedure, regardless of the # of grafts used)
Received from a tissue establishment (transport) in
another EU country Parathyroid tissue # of containers
Exports (non EU) Parathyroid tissue # of containers
Exports (non EU) Hepatocytes # of containers
# of containers
Parathyroid tissue # of containers
Imports (non EU) Parathyroid tissue # of containers
Distributed to end user in another EU country Parathyroid tissue # of containers
Sent to a tissue establishment (transport) in another EU country Parathyroid tissue
UNITS/EXPLANATIONS
Living donors # of living parathyroid tissue donors at national level
Deceased donors # of deceased parathyroid tissue donors at national level
Parathyroid tissue donations # of donation events from one donor, regardless of the number of tissues obtained
Donors
# of containers
Releases for clinical application, whether distributed or not
Distributed to end user in the country Parathyroid tissue # of containers
# of containers
Applications # of applications (one procedure, regardless of the # of grafts used)
PR 8
PR 9
PR 10
PR 11
HE 10
HE 11
PR 1
PR 2
PR 3
PR 4
PR 5
PR 6
PR 7
HE 4
HE 5
HE 6
HE 7
HE 8
HE 9
Work Package 7 / GA 2018 53 01 9 of 14 PA/PH/TO (21) 02
COUNTRY YEAR
Registered at 01/01 00:00
IMPORT EXPORT
Nationally From EU countries To EU countries From non-EU
countries To non-EU countries
Paediatric (<18 yr.) Adult
RELEASED FOR CLINICAL APPLICATION AUTOLOGOUS
Related donor Unrelated registry donor
D O
N A
TI O
N C
EN TR
E
TE a 5 TE a 6 TE a 7
DC a 4 DC a 5 DC a 6
TE a 1 TE a 2
SS b 4 SS b 5
DC a 1 DC a 2 DC a 3
SS a 1 SS a 2
SS b 1 SS b 2 SS b 3
HAEMATOPOIETIC CELLS ACTIVITY DATA
Unrelated registry donor
HPC from peripheral blood for transplantation Peripheral blood mononuclear cells for transplant support (e.g. donor lymphocytes for infusion) Peripheral blood mononuclear cells for other purposes, excluding ATMP (e.g. production of CAR-T cells, NK cells)
HPC from peripheral blood for transplantation Peripheral blood mononuclear cells for transplant support (e.g. donor lymphocytes for infusion) Peripheral blood mononuclear cells for other purposes, excluding ATMP (e.g. production of CAR-T cells, NK cells) HPC from cord blood for transplantation
HPC from bone marrow for transplantation
AUTOLOGOUS
SE LF
-S U
FF IC
IE N
C Y
DISTRIBUTED
Related donor ALLOGENEIC
TI SS
U E
ES TA
B LI
SH EM
EN T ALLOGENEIC
Other cells (e.g. bone marrow for other purposes), excluding ATMP
TE a 3 TE a 4
DONATION/COLLECTION
POTENTIAL FOR ALLOGENEIC DONATION
# of registered and typed HPC donors # of registered and typed cord blood units available for transplantation of unrelated patients
DISTRIBUTION AND EXCHANGE
# of unrelated (unit: Cell product from one donor, regardless of the number of donations/containers)
HPC from bone marrow for transplantation
HPC from peripheral blood for transplantation Peripheral blood mononuclear cells for transplant support (e.g. donor lymphocytes for infusion) Peripheral blood mononuclear cells for other purposes, excluding ATMP (e.g. production of CAR-T cells, NK cells) HPC from cord blood for transplantation Cord blood for other purposes, excluding ATMP (e.g. production of NK cells, mesenchymals)
HPC from cord blood Other cells (e.g. bone marrow for other purposes), excluding ATMP
# of donations (unit: Cell product collected from one donor in one donation procedure - may encompass more than one apheresis session)
# released for clinical application, whether distributed or not (unit: Cell product collected from one donor in one donation procedure - may encompass more than one apheresis session) HPC from bone marrow for transplantation
PA/PH/TO (21) 02 10 of 14 Work Package 7 / GA 2018 53 01
AUTOLOGOUS
Related donor Unrelated registry donor
AUTOLOGOUS
Related donor Unrelated registry donor
TC b 3 TC b 4 TC b 5
TC a 3 TC a 4 TC a 5
TC b 1 TC b 2
TC a 1 TC a 2
ALLOGENEIC
TR A
N SP
LA N
T C
EN TR
ES
OTHER PROCEDURES ASSOCIATED WITH CLINICAL APPLICATION
Peripheral blood mononuclear cells for other purposes (e.g. NK cells, Tregs, virus-specific cells), excluding ATMP Other cells for other purposes, excluding ATMP
# of procedures (unit: One application with cells obtained from one or more donors)
# of transplants (unit: One transplant procedure with cells obtained from one or more donors) # of recipients (unit: One patient who had at least one transplant procedure during the year concerned) HPC from bone marrow for transplantation HPC from peripheral blood for transplantation
TRANSPLANT PROCEDURES ASSOCIATED WITH CLINICAL APPLICATION
HPC from cord blood for transplantation
# of recipients (unit: One patient who had at least one procedure during the year concerned) Peripheral blood mononuclear cells for transplant support (e.g. donor lymphocytes for infusion)
ALLOGENEIC
Work Package 7 / GA 2018 53 01 11 of 14 PA/PH/TO (21) 02
COUNTRY YEAR
IUI IVF/ICSI Frozen/cryo embryo transfers (FET)
# of couples treated
# of treatment cycles without stimulation
# of treatment cycles with stimulation
PARTNER GAMETES/EMBRYOS Numbers (regardless of treatment type)
# of oocyte retrievals
# of oocytes retrieved
# of oocytes cryopreserved
# of sperm collections (including MESA, PESA and TESE)
# of sperm units cryopreserved
# of embryos cryopreserved
# of embryo transfers (fresh or cryo)
# of embryos transferred (fresh or cryo)
# of embryos transferred (fresh or cryo) from donated sperm and partner oocytes # of embryos transferred (fresh or cryo) from donated oocytes and partner sperm
IMPORT EXPORT From other EU countries To other EU countries From non-EU countries To non-EU countries
# of oocytes
# of sperm units
# of embryos
# of ovarian tissues
# of testicular tissues (including MESA, PESA and TESE)
Treatment type IUI IVF/ICSI (fresh or cryo)
# of deliveries
# of live born children
# of oocytes
# of straws/vials
# of embryos
# of procedures, regardless of the number of embryos transferred
# of embryos
# of embryos
# of embryos
PA b 8
PA b 9
PA c 5
MAR ACTIVITY DATA
PA d 1
PA d 2
PA b 10
PA c 1
PA c 2
PA c 3
PA c 4
# of cycles with ovarian stimulation (excludes hormone substituted cycles) that ended up with one of the interventions
# of couples that had at least one treatment cycle intervention (IUI, IVF/ICSI and/or FET) completed
UNITS/EXPLANATIONS
# of cycles without ovarian stimulation (includes hormone substituted cycles) that ended up with one of the interventions
MAR PARTNER ACTIVITIES
PA a 1
PA a 2
PA a 3
PA b 1
PA b 2
PA b 3
PA b 4
# of retrieval procedures where at least one oocyte was retrieved
# of oocytes retrieved in total
# oocytes cryopreserved in total
# of collections, regardless of number of straws and method of collection used
UNITS/EXPLANATIONS
# of vials/containers
TRANSPORT/DISTRIBUTION
PA R
TN ER
P R
O C
ED U
R ES
Treatment type
DELIVERIES AND LIVE BORN CHILDREN (born during the reporting year regardless of when conceived) UNITS/EXPLANATIONS
# of deliveries regardless of the number of children born (including stillborn)
# of infants with any vital signs
DISTRIBUTION AND EXCHANGE OF PARTNER GAMETES/TISSUES/EMBRYOS (ACCESS TO CARE)
# of vials/containers
# of straws/vials
# of embryos
UNITS/EXPLANATIONS
PA b 5
PA b 6
PA b 7
PA/PH/TO (21) 02 12 of 14 Work Package 7 / GA 2018 53 01
NON-PARTNER GAMETES/EMBRYOS Numbers (regardless of treatment type)
# of oocyte donors for dedicated and split donation cycles
# of oocyte donors of supernumerary oocytes (from partner procedures)
# of oocyte retrievals intended for donation (dedicated or split)
# of oocytes donated (dedicated, split or supernumerary)
# of oocytes cryopreserved (dedicated, split or supernumerary)
# of sperm donors
# of sperm collections
# of sperm units cryopreserved
# of embryos donated
IMPORT EXPORT From other EU countries To other EU countries From non-EU countries To non-EU countries
# of sperm units
# of donated embryos
Treatment type IUI IVF/ICSI
# of recipients
# of treatment cycles with donated sperm
# of partner oocyte retrievals
# of embryos cryopreserved
# of embryo transfers (fresh or cryo)
# of embryos transferred (fresh or cryo)
MAR with non partner OOCYTE donation IVF/ICSI
# of recipients
# of treatment cycles with donated oocytes
# of partner sperm collections
# of embryos cryopreserved
# of embryo transfers (fresh or cryo)
# of embryos transferred (fresh or cryo)
MAR with non partner OOCYTES AND SPERM donation (double donation) IVF/ICSI
# of recipients
# of treatment cycles with donated oocytes and sperm
# of embryos cryopreserved
NP a 3
NP a 4
NP a 5
NP a 6
NP a 7
NP a 8
NP a 9
NP b 1
NP b 2
# of retrieval procedures where at least one oocyte was retrieved
# women who underwent at least one embryo transfer involving donated oocytes (in the reporting country)
NP c 1
NP c 2
NP c 3
NP d 5
NP e 3
UNITS/EXPLANATIONS
# of straws/vials
NP d 3
MAR with non partner SPERM donation
DISTRIBUTION AND EXCHANGE OF NON-PARTNER GAMETES/EMBRYOS (COMMERCIALISATION)
# of embryos (cryopreserved) from donated oocytes
# of procedures involving donated oocytes, regardless of the number of embryos transferred
# of embryos (transferred) from donated oocytesNP d 6
NP e 1
NP e 2
# of cycles, with or without ovarian stimulation, where donated sperm was used
# of embryos (cryopreserved) from donated sperm
# of embryos (transferred) from donated sperm
# of transfer procedures involving donated sperm, regardless of the number of embryos transferred
UNITS/EXPLANATIONS
UNITS/EXPLANATIONS
NP d 4
NP c 4
NP c 5
NP c 6
NP d 1
NP d 2
NP a 1
NP a 2
N O
N -P
A R
TN ER
P R
O C
ED U
R ES
TRANSPORT/DISTRIBUTION
# of donors of supernumerary oocytes from partner procedures, regardless of the number of donations
# of straws/vials
UNITS/EXPLANATIONS
# of donors (recruited for the specific purpose of donation), regardless of the number of donations
# women who underwent at least one embryo transfer involving donated oocytes and sperm (in the reporting country)
# of embryos (cryopreserved ) from donated oocytes and sperm
# of cycles, stimulated or non-stimulated, where donated oocytes were used
UNITS/EXPLANATIONS
# of cycles, stimulated or non-stimulated, where donated oocytes and sperm were used
# of collections, regardless of the number of straws
# of embryos
# women who underwent IUI and/or an embryo transfer involving donated sperm (in the reporting country)
# of collections, regardless of the number of straws
# of embryos (supernumerary after partner and non-partner treatments)
# of donors who provided at least one sample during the year
# of oocytes
# of oocytes
# of retrieval procedures where at least one oocyte was retrieved
Work Package 7 / GA 2018 53 01 13 of 14 PA/PH/TO (21) 02
# of embryo transfers (fresh or cryo)
# of embryos transferred (fresh or cryo)
MAR with EMBRYO donation (supernumerary from partner or non-partner treatments) IVF/ICSI
# of recipients
# of treatment cycles with donated embryos
# of embryo transfers (fresh or cryo)
# of embryos transferred (fresh or cryo)
Treatment type IUI IVF/ICSI (fresh or cryo)
# of deliveries
# of live born children
FERTILITY PRESERVATION Numbers
# of patients who underwent one or more oocyte retrievals
# of oocyte retrieval procedures
# of patients who underwent one or more sperm collections (including MESA, PESA and TESE) # of sperm collection procedures (including MESA, PESA and TESE)
# of patients who underwent an ovarian tissue collection
# of ovarian tissue collection procedures
# of patients who underwent a collection of immature testicular tissue
# of immature testicular tissue collection procedures
# of patients who underwent an ovarian tissue transplantation
NP f 2
NP e 4
NP e 5
NP f 1
FP a 6
FP a 7
FP a 8
FP a 9
FP a 1
FP a 2
FP a 3
FP a 4
FP a 5
FE R
TI LI
TY P
R ES
ER VA
TI O
N
DELIVERIES AND LIVE BORN CHILDREN (during the reporting year regardless of when conceived)
NP g 1
NP g 2
# of patients who underwent an ovarian tissue transplantation, regardless of the number of tissue fragments transplanted
# of patients who underwent a collection procedure of immature testicular tissue (i.e. not containing sperm), regardless of the amount of tissue collected
# of patients who underwent an ovarian tissue collection procedure, regardless of the amount of tissue collected
# of immature testicular tissue collection procedures, regardless of the amount of tissue collected
# of sperm collection procedures (including MESA, PESA and TESE with mature sperm extracted), regardless of the amount of straws/vials obtained
# of ovarian tissue collection procedures, regardless of the amount of tissue collected
# of oocyte retrieval procedures, regardless of the number of oocytes retrieved
# of patients who underwent at least one sperm collection procedure (including MESA, PESA and TESE with mature sperm extracted), regardless of the amount of straws/vials obtained
# of patients who underwent at least one oocyte retrieval procedure, regardless of the number of oocytes retrieved
UNITS/EXPLANATIONS
NP f 3
NP f 4
# of infants with any vital signs
# of procedures involving donated supernumerary embryos regardless of the number of embryos transferred
# of embryos (transferred) from donated supernumerary embryos
# women who underwent at least one embryo transfer involving donated supernumerary embryos (in the reporting country)
UNITS/EXPLANATIONS
# of deliveries, regardless of the number of children born (including stillborn)
# of cycles, stimulated or non-stimulated, where donated supernumerary embryos were used
UNITS/EXPLANATIONS
# of embryos (transferred) from donated oocytes and sperm
# of procedures involving donated oocytes and sperm, regardless of the number of embryos transferred
PA/PH/TO (21) 02 14 of 14 Work Package 7 / GA 2018 53 01