| Dokumendiregister | Ravimiamet |
| Viit | RST-1/4774-4 |
| Registreeritud | 26.01.2025 |
| Sünkroonitud | 27.01.2025 |
| Liik | Väljaminev kiri |
| Funktsioon | RST Ravimistatistika tegemine |
| Sari | RST-1 Ravimistatistika alane kirjavahetus |
| Toimik | RST-1/2024 |
| Juurdepääsupiirang | Avalik |
| Juurdepääsupiirang | |
| Adressaat | Organisation for Economic Co-operation and Development |
| Saabumis/saatmisviis | Organisation for Economic Co-operation and Development |
| Vastutaja | Janne Sepp (RA, Peadirektori asetäitja valdkond, Ravimiohutuse osakond, Statistikabüroo) |
| Originaal | Ava uues aknas |
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day A ALIMENTARY TRACT AND METABOLISM 176,5588 A01 STOMATOLOGICAL PREPARATIONS 0,0742 A01A STOMATOLOGICAL PREPARATIONS 0,0742 A01AB Antiinfectives and antiseptics for local oral treatment 0,0742 A01AB09 Miconazole(O) 7174,4 g 0,2 g 0,0742 A01AB12 Hexetidine(O) 1154880 ml A01AB81 Neomycin+Benzocaine(dental) 14050 pieces A01AB82 Demeclocycline+Triamcinolone(dental) 780 g A01AD Other agents for local oral treatment A01AD80 Lidocaine+Cetylpyridinium chloride(gingival) 154380 g A01AD81 Lidocaine+Cetrimide(O) 53485 g A01AD82 Choline salicylate(O) 645600 pieces A01AD83 Lidocaine+Chamomille extract(O) 391340 g A01AD90 Lidocaine+Paraformaldehyde(dental) 444 g A02 DRUGS FOR ACID RELATED DISORDERS 56,2174 A02A ANTACIDS 1,1870
A02AD Combinations and complexes of aluminium, calcium and magnesium compounds
1,1870
A02AD81 Aluminium hydroxide+Magnesium hydroxide(O) 851440 pieces 10 pieces 0,1761 A02AD81 Aluminium hydroxide+Magnesium hydroxide(O) 3907014 ml 50 ml 0,1616 A02AD83 Calcium carbonate+Magnesium carbonate(O) 4107672 pieces 10 pieces 0,8494
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
55,0304
A02BA H2-receptor antagonists 1,3430 A02BA02 Ranitidine(O) 192291,75 g 0,3 g 1,3254 A02BA02 Ranitidine(P) 2568 g 0,3 g 0,0177 A02BC Proton pump inhibitors 53,6743 A02BC01 Omeprazole(O) 283739,28 g 0,02 g 29,3346 A02BC02 Pantoprazole(O) 258796,44 g 0,04 g 13,3779 A02BC02 Pantoprazole(P) 461,6 g 0,04 g 0,0239 A02BC03 Lansoprazole(O) 4,2 g 0,03 g 0,0003 A02BC05 Esomeprazole(O) 155634,92 g 0,03 g 10,7270 A02BC05 Esomeprazole(P) 3055,6 g 0,03 g 0,2106 A02BC08 Vonoprazan(O) 4 g A02BD Combinations for eradication of Helicobacter pylori 0,0011 A02BD08 Bismuth subcitrate+Tetracycline+Metronidazole (O) 6240 pieces 12 pieces 0,0011
A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
0,0120
A02BX02 Sucralfate(O) 22800 g 4 g 0,0118 A02BX03 Pirenzepine(O) 10 g 0,1 g 0,0002 A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS 8,2131
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS 7,2698
A03AA Synthetic anticholinergics, esters with tertiary amino group 1,0663 A03AA04 Mebeverine(O) 154704 g 0,3 g 1,0663 A03AB Synthetic anticholinergics, quaternary ammonium compounds 0,0003 A03AB02 Glycopyrronium(P) 0,046 g 0,3 mg 0,0003 A03AD Papaverine and derivatives 4,5268 A03AD01 Papaverine hydrochloride(P) 66,8 g 0,1 g 0,0014 A03AD02 Drotaverine(O) 215250,88 g 0,1 g 4,4508 A03AD02 Drotaverine(P) 3608 g 0,1 g 0,0746 A03AX Other drugs for functional gastrointestinal disorders 1,6764 A03AX13 Simeticone(O) 405384,432 g 0,5 g 1,6764 A03B BELLADONNA AND DERIVATIVES, PLAIN 0,0828 A03BA Belladonna alkaloids, tertiary amines 0,0728 A03BA01 Atropine(O, P) 12,81 g 0,0015 g 0,0177 A03BA01 Atropine(P) 40,02 g 0,0015 g 0,0552
A03BB Belladonna alkaloids, semisynthetic, quaternary ammonium compounds
0,0100
A03BB01 Hyoscine butylbromide(O) 21,4 g 0,06 g 0,0007
1/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day A03BB01 Hyoscine butylbromide(P) 266,8 g 0,06 g 0,0092 A03BB01 Hyoscine butylbromide(R) 1,92 g 0,06 g 0,0001 A03F PROPULSIVES 0,8605 A03FA Propulsives 0,8605 A03FA01 Metoclopramide(O) 10342 g 0,03 g 0,7128 A03FA01 Metoclopramide(P) 1687,1 g 0,03 g 0,1163 A03FA03 Domperidone(O) 455,91 g 0,03 g 0,0314 A04 ANTIEMETICS AND ANTINAUSEANTS 0,1210 A04A ANTIEMETICS AND ANTINAUSEANTS 0,1210 A04AA Serotonin (5-HT3) antagonists 0,1122 A04AA01 Ondansetron(P) 113,02 g 0,016 g 0,0146 A04AA02 Granisetron(O) 60,23 g 0,002 g 0,0623 A04AA02 Granisetron(P) 49,83 g 0,003 g 0,0343 A04AA05 Palonosetron(P) 0,008 g 0,25 mg 0,0001 A04AA80 Palonosetron+Netupitant(O) 449 pieces 1 pieces 0,0009 A04AD Other antiemetics 0,0088 A04AD01 Scopolamine(TD) 10 pieces 1 pieces <0,0001 A04AD12 Aprepitant(O) 285,855 g 0,165 g 0,0036 A04AD81 Fosaprepitant(P) 238,35 g 0,095 g 0,0052 A05 BILE AND LIVER THERAPY 2,0881 A05A BILE THERAPY 0,5485 A05AA Bile acids and derivatives 0,5485 A05AA02 Ursodeoxycholic acid(O) 198962,5 g 0,75 g 0,5485 A05B LIVER THERAPY, LIPOTROPICS 1,5396 A05BA Liver therapy 1,5396 A05BA03 Silymarin(O) 2121160 pieces A05BA80 Phospholipids from Soya Beans(O) 1380900 pieces 3 pieces 0,9518 A05BA80 Phospholipids from Soya Beans(O) 1705700 pieces 6 pieces 0,5878 A05BA80 Phospholipids from Soya Beans(P) 975 pieces A05BA81 Silibinin(P) 56 g A06 DRUGS FOR CONSTIPATION 16,4173 A06A DRUGS FOR CONSTIPATION 16,4173 A06AB Contact laxatives 7,5294 A06AB02 Bisacodyl(O) 14242,8 g 0,01 g 2,9450 A06AB02 Bisacodyl(R) 986,3 g 0,01 g 0,2039 A06AB06 Senna glycosides(O) 6380 pieces 1 pieces 0,0132 A06AB08 Sodium picosulfate(O) 10551,9264 g 0,005 g 4,3637 A06AB80 Sodium picosulfate+Magnesium oxide+Citric acid(O) 3426 pieces 2 pieces 0,0035 A06AC Bulk-forming laxatives <0,0001 A06AC01 Hemicellulose of Ispaghula(O) 0,585 g 7 g <0,0001 A06AD Osmotically acting laxatives 7,9377 A06AD11 Lactulose(O) 24311273,4 g 6,7 g 7,5028 A06AD15 Macrogol(O) 2103400 g 10 g 0,4349
A06AD80 Macrogol+Sodium citrate+Citric acid+Sodium chloride+Potassium chloride(O)
21500 ml
A06AD81 Sodium sulphate, anhydrous+Potassium chloride+Sodium chloride+Macrogol+Sodium hydrogen carbonate(O)
40940 pieces
A06AD83 Macrogol+Sodium sulphate, anhydrous+Sodium chloride+Potassium chloride+Ascorbic acid+Sodium ascorbate(O)
5843 pieces
A06AD85 Sodium sulphate, anhydrous+magnesium sulfate heptahydrate+Potassium sulphate(O)
934912 ml
A06AG Enemas 0,9313 A06AG11 Laurilsulfate, incl. combinations+Sorbitol+Sodium citrate(R) 450392 pieces 1 pieces 0,9313 A06AH Peripheral opioid receptor antagonists 0,0189 A06AH03 Naloxegol(O) 228,75 g 25 mg 0,0189
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
4,6470
A07A INTESTINAL ANTIINFECTIVES 0,0010 A07AA Antibiotics 0,0010
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day A07AA02 Nystatin(O) 60000000 U 1500000 U 0,0001 A07AA11 Rifaximin(O) 252 g 0,6 g 0,0009 A07AA12 Fidaxomicin(O) 4 g 0,4 g <0,0001 A07B INTESTINAL ADSORBENTS 0,5281 A07BC Other intestinal adsorbents 0,5281 A07BC05 Diosmectidum(O) 2298540 g 9 g 0,5281 A07C ELECTROLYTES WITH CARBOHYDRATES A07CA Oral rehydration salt formulations
A07CA80 Sodium chloride+Potassium chloride+Sodium citrate+Glucose(O) 48820 pieces
A07D ANTIPROPULSIVES 1,0787 A07DA Antipropulsives 1,0787 A07DA03 Loperamide(O) 5217,02 g 0,01 g 1,0787 A07E INTESTINAL ANTIINFLAMMATORY AGENTS 2,2662 A07EA Corticosteroids acting locally 0,0088 A07EA06 Budesonide(O) 38,4 g 0,009 g 0,0088 A07EA06 Budesonide(R) 2,5375 g A07EC Aminosalicylic acid and similar agents 2,2574 A07EC01 Sulfasalazine(O) 791900 g 2 g 0,8187 A07EC02 Mesalazine(O) 953300 g 1,5 g 1,3141 A07EC02 Mesalazine(R) 90360 g 1,5 g 0,1246 A07F ANTIDIARRHEAL MICROORGANISMS 0,7730 A07FA Antidiarrheal microorganisms 0,7730 A07FA02 Saccharomyces boulardii(O) 373845 g 1 g 0,7730 A07X OTHER ANTIDIARRHEALS A07XA Other antidiarrheals A07XA04 Racecadotril(O) 3490,64 g A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0649 A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0649 A08AA Centrally acting antiobesity products 0,0643 A08AA62 Bupropione+Naltrexone(O) 124432 pieces 4 pieces 0,0643 A08AB Peripherally acting antiobesity products 0,0006 A08AB01 Orlistat(O) 105,84 g 0,36 g 0,0006 A09 DIGESTIVES, INCL. ENZYMES 1,6015 A09A DIGESTIVES, INCL. ENZYMES 1,6015 A09AA Enzyme preparations 1,6015 A09AA02 Lipase+Amylase+Protease(O) 3098159 pieces 4 pieces 1,6015 A10 DRUGS USED IN DIABETES 65,0155 A10A INSULINS AND ANALOGUES 16,1124 A10AB Insulins and analogues for injection, fast-acting 6,0895 A10AB01 Insulin (human)(P) 996000 U 40 U 0,0515 A10AB04 Insulin lispro(P) 22677000 U 40 U 1,1722 A10AB05 Insulin aspart(P) 81877500 U 40 U 4,2325 A10AB06 Insulin glulisine(P) 12250500 U 40 U 0,6333 A10AC Insulins and analogues for injection, intermediate-acting 0,0743 A10AC01 Insulin (human)(P) 1437000 U 40 U 0,0743
A10AD Insulins and analogues for injection, intermediate- or long-acting combined with fast-acting
0,9251
A10AD04 Insulin lispro(P) 5487000 U 40 U 0,2836 A10AD05 Insulin aspart(P) 12409500 U 40 U 0,6415 A10AE Insulins and analogues for injection, long-acting 9,0235 A10AE04 Insulin glargine(P) 100768500 U 40 U 5,2090 A10AE05 Insulin detemir(P) 51253500 U 40 U 2,6494 A10AE06 Insulin degludec(P) 18664500 U 40 U 0,9648 A10AE54 Insulin glargine+Lixisenatide(P) 3873000 U 40 U 0,2002 A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS 48,9031 A10BA Biguanides 20,7978 A10BA02 Metformin(O) 20116659 g 2 g 20,7978 A10BB Sulfonylureas 12,7685 A10BB07 Glipizide(O) 919,2 g 0,01 g 0,1901
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day A10BB09 Gliclazide(O) 206602,2 g 0,06 g 7,1199 A10BB12 Glimepiride(O) 5279,79 g 0,002 g 5,4586 A10BD Combinations of oral blood glucose lowering drugs 6,9312 A10BD07 Metformin+Sitagliptin(O) 2027816 pieces 2 pieces 2,0965 A10BD08 Metformin+Vildagliptin(O) 1276740 pieces 2 pieces 1,3200 A10BD10 Metformin+Saxagliptin(O) 335820 pieces 2 pieces 0,3472 A10BD11 Metformin+Linagliptin(O) 1038300 pieces 2 pieces 1,0735 A10BD15 Metformin+Dapagliflozin(O) 547456 pieces 2 pieces 0,5660 A10BD19 Linagliptin+Empagliflozin(O) 143970 pieces 1 pieces 0,2977 A10BD20 Metformin+Empagliflozin(O) 1010580 pieces 2 pieces 1,0448 A10BD21 Saxagliptin+Dapagliflozin(O) 87836 pieces 1 pieces 0,1816 A10BD23 Metformin+Ertugliflozin(O) 1960 pieces 1 pieces 0,0041 A10BF Alpha glucosidase inhibitors 0,0009 A10BF01 Acarbose(O) 131,25 g 0,3 g 0,0009 A10BG Thiazolidinediones 0,1301 A10BG03 Pioglitazone(O) 1887,06 g 0,03 g 0,1301 A10BH Dipeptyl peptidase 4 (DPP-4) inhibitors 3,9646 A10BH01 Sitagliptin(O) 59508,4 g 0,1 g 1,2305 A10BH02 Vildagliptin(O) 8541 g 0,1 g 0,1766 A10BH03 Saxagliptin(O) 567,6 g 5 mg 0,2347 A10BH05 Linagliptin(O) 5616,75 g 5 mg 2,3228 A10BJ Glucagon-like peptide-1 (GLP-1) analogues 2,0412 A10BJ01 Exenatide(P) 7,72 g 0,286 mg 0,0558 A10BJ02 Liraglutide(P) 911,232 g 1,5 mg 1,2561 A10BJ03 Lixisenatide(P) 0,8871 g 20 mcg 0,0917 A10BJ05 Dulaglutide(P) 14,037 g 0,16 mg 0,1814 A10BJ06 Semaglutide(P) 24,269 g 0,11 mg 0,4562 A10BK Sodium-glucose co-transporter 2 (SGLT2) inhibitors 2,2688 A10BK01 Dapagliflozin(O) 4434,15 g 10 mg 0,9169 A10BK03 empagliflozin(O) 11436,75 g 17,5 mg 1,3513 A10BK04 Ertugliflozin(O) 2,94 g 10 mg 0,0006 A11 VITAMINS 12,5386 A11A MULTIVITAMINS, COMBINATIONS 1,4917 A11AA Multivitamins with minerals 1,4917 A11AA03 Multivitamins+Mineral elements(O) 721440 pieces 1 pieces 1,4917 A11B MULTIVITAMINS, PLAIN 0,0003 A11BA Multivitamins, plain 0,0003 A11BA80 Multivitamins(O) 1250 ml 10 ml 0,0003 A11C VITAMIN A AND D, INCL. COMBINATIONS OF THE TWO 2,4546 A11CC Vitamin D and analogues 2,4546 A11CC04 Calcitriol(O) 0,0974 g 0,001 mg 0,2013 A11CC05 Colecalciferol(O) 435900000 U 400 U 2,2533 A11CC05 Colecalciferol(P) 10000000 U
A11D VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN B6 AND B12
1,8820
A11DA Vitamin B1, plain 0,3818 A11DA01 Thiamine(P) 9232 g 0,05 g 0,3818 A11DA03 Benfotiamine(O) 1747420 pieces A11DB Vitamin B1 in combination with vitamin B6 and/or vitamin B12 1,5002 A11DB80 Thiamine+Pyridoxine(P) 3300 pieces 1 pieces 0,0068 A11DB81 Benfotiamine+Pyridoxine(O) 206250 pieces 3 pieces 0,1422 A11DB84 Thiamine+Pyridoxine+Cyanocobalamin(O) 572570 pieces 1 pieces 1,1839 A11DB85 Thiamine+Pyridoxine+Cyanocobalamin+Lidocaine(P) 80920 pieces 1 pieces 0,1673 A11E VITAMIN B-COMPLEX, INCL. COMBINATIONS 0,6135 A11EA Vitamin B-complex, plain 0,6135
A11EA80 Thiamine+Nicotinamide+Riboflavin+Calcium pantothenate+Pyridoxine(O)
296700 pieces 1 pieces 0,6135
A11G ASCORBIC ACID (VITAMIN C), INCL. COMBINATIONS 0,1727 A11GA Ascorbic acid (vitamin C), plain 0,1727 A11GA01 Ascorbic acid(P) 16702,5 g 0,2 g 0,1727
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day A11H OTHER PLAIN VITAMIN PREPARATIONS 0,0640 A11HA Other plain vitamin preparations 0,0640 A11HA02 Pyridoxine(O) 90 g 0,16 g 0,0012 A11HA02 Pyridoxine(P) 4434,5 g 0,16 g 0,0573 A11HA03 Tocopherol(O) 40 g 0,2 g 0,0004 A11HA08 Tocofersolan(O) 495 g 0,2 g 0,0051 A11J OTHER VITAMIN PRODUCTS, COMBINATIONS 5,8598 A11JB Vitamins with minerals 5,8598 A11JB81 Pyridoxine+Magnesium(O) 7201900 pieces 4 pieces 3,7229
A11JB82 Thiamine+Riboflavin+Pyridoxine+Cyanocobalamin+Ascorbic acid+Biotin+Nicotinamide+Calcium pantothenate+Calcium+Magnesium+Folic acid+Zinc(O)
1033470 pieces 1 pieces 2,1369
A12 MINERAL SUPPLEMENTS 9,0463 A12A CALCIUM 5,4182 A12AA Calcium 0,7933 A12AA03 Calcium gluconate(P) 24775 g 3 g 0,0171 A12AA04 Calcium carbonate(O) 1126150 g 3 g 0,7762 A12AX Calcium, combinations with vitamin D and/or other drugs 4,6249 A12AX80 Calcium+Colecalciferol(O) 600000 pieces 1 pieces 1,2406 A12AX80 Calcium+Colecalciferol(O) 3273480 pieces 2 pieces 3,3843 A12B POTASSIUM 3,0809 A12BA Potassium 3,0809 A12BA01 Potassium chloride(O) 319140 g 3 g 0,2200 A12BA02 Potassium citrate(O) 432 g 4 g 0,0002 A12BA80 Potassium chloride+Potassium hydrogen carbonate(O) 7900 pieces A12BA81 Potassium aspartate+Magnesium aspartate(O) 4102350 pieces 3 pieces 2,8275 A12BA81 Potassium aspartate+Magnesium aspartate(P) 16085 pieces 1 pieces 0,0333 A12C OTHER MINERAL SUPPLEMENTS 0,5472 A12CC Magnesium 0,5472 A12CC04 Magnesium citrate(O) 529247,912 g 2 g 0,5472 A12CX Other mineral products A12CX83 Phosphate(O) 11200 pieces A14 ANABOLIC AGENTS FOR SYSTEMIC USE 0,0021 A14A ANABOLIC STEROIDS 0,0021 A14AB Estren derivatives 0,0021 A14AB01 Nandrolone(P) 2 g 0,002 g 0,0021 A14B OTHER ANABOLIC AGENTS A14BX Other anabolic agents A14BX80 Riboxine(O) 90 g A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS 0,5117 A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS 0,5117 A16AA Amino acids and derivatives 0,0022 A16AA01 Levocarnitine(O) 1680 g 2 g 0,0017 A16AA02 Ademetionine(O) 395 g A16AA04 Mercaptamine(O) 120 g 2 g 0,0001 A16AA05 Carglumic acid(O) 22 g 0,2 g 0,0002 A16AA06 Betaine(O) 180 g 6 g 0,0001 A16AA80 L-arginiin(O) 90 g A16AA81 Glycine(O) 900 g A16AB Enzymes 0,0063 A16AB02 Imiglucerase(P) 196400 U 300 U 0,0014 A16AB03 Agalsidase alfa(P) 1,323 g 0,001 g 0,0027 A16AB04 Agalsidase beta(P) 2,32 g 0,005 g 0,0010 A16AB07 Alglucosidase alfa(P) 60 g 0,1 g 0,0012 A16AB09 Idursulfase(P) 1,344 g A16AX Various alimentary tract and metabolism products 0,5033 A16AX01 Thioctic acid(O) 142794 g 0,6 g 0,4921 A16AX01 Thioctic acid(P) 327 g 0,6 g 0,0011 A16AX03 Sodium phenylbutyrate(O) 3000 g 20 g 0,0003 A16AX05 Zinc(O) 681,25 g 0,15 g 0,0094
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day A16AX07 Sapropterin(O) 684 g A16AX10 Eliglustat(O) 18,816 g 0,168 g 0,0002 A16AX15 Telotristat(O) 45 g 0,75 g 0,0001 A16AX80 Creatine(O) 450 g A16AX81 Copper histidine(P) 0,105 g B BLOOD AND BLOOD FORMING ORGANS 107,7585 B01 ANTITHROMBOTIC AGENTS 83,1567 B01A ANTITHROMBOTIC AGENTS 83,1567 B01AA Vitamin K antagonists 2,9920 B01AA03 Warfarin(O) 10852,5 g 0,0075 g 2,9920 B01AB Heparin group 3,1593 B01AB01 Heparin sodium(P) 680500000 U 10000 U 0,1407 B01AB04 Dalteparin sodium(P) 1850000 U 2500 U 0,0015 B01AB05 Enoxaparin sodium(hem, P) 590108000 U 2000 U 0,6101 B01AB05 Enoxaparin sodium(P) 1827824000 U 2000 U 1,8897 B01AB06 Nadroparin calcium(P) 10849000 U 2850 U 0,0079 B01AB12 Bemiparin sodium(P) 615835000 U 2500 U 0,5093 B01AC Platelet aggregation inhibitors, excl. heparin 57,8181 B01AC04 Clopidogrel(O) 157415,25 g 0,075 g 4,3399 B01AC06 Acetylsalicylic acid (O) 5467750 pieces 1 pieces 11,3058 B01AC07 Dipyridamole(O) 44,1 g 0,4 g 0,0002 B01AC09 Epoprostenol(P) 0,003 g B01AC11 Iloprost(I) 0,121 g 0,15 mg 0,0017 B01AC11 Iloprost(P) 0,009 g 50 mcg 0,0004 B01AC16 Eptifibatide(P) 72,56 g 0,2 g 0,0008 B01AC24 Ticagrelor(O) 97450,08 g 0,18 g 1,1194 B01AC80 Acetylsalicylic acid +Magnesium oxide(O) 19852800 pieces 1 pieces 41,0500 B01AD Enzymes 0,0024 B01AD01 Streptokinase(P) 107500000 U 1500000 U 0,0001 B01AD02 Alteplase(P) 90,83 g 0,1 g 0,0019 B01AD11 Tenecteplase(P) 6,75 g 0,04 g 0,0003 B01AE Direct thrombin inhibitors 2,7763 B01AE07 Dabigatran etexilate(O) 402802,4 g 0,3 g 2,7763 B01AF Direct factor Xa inhibitors 16,4061 B01AF01 Rivaroxaban(O) 88914,18 g 0,02 g 9,1925 B01AF02 Apixaban(O) 34884,9 g 10 mg 7,2132 B01AF03 Edoxaban(O) 10,8 g 60 mg 0,0004 B01AX Other antithrombotic agents 0,0027 B01AX05 Fondaparinux sodium(P) 3,225 g 0,0025 g 0,0027 B02 ANTIHEMORRHAGICS 0,1720 B02A ANTIFIBRINOLYTICS 0,1528 B02AA Amino acids 0,1528 B02AA01 Aminocaproic acid(P) 12980 g 16 g 0,0017 B02AA02 Tranexamic acid(O) 108820 g 2 g 0,1125 B02AA02 Tranexamic acid(P) 37348 g 2 g 0,0386 B02B VITAMIN K AND OTHER HEMOSTATICS 0,0193 B02BA Vitamin K 0,0040 B02BA01 Phytomenadione(O, P) 36,94 g 0,02 g 0,0038 B02BA01 Phytomenadione(P) 1,62 g 0,02 g 0,0002 B02BB Fibrinogen 0,0001 B02BB01 Fibrinogen human(P) 135 g 5 g 0,0001 B02BC Local hemostatics B02BC81 Fibrinogen human+Human thrombin(epil) 665 pieces B02BD Blood coagulation factors B02BD01 Human prothrombin complex(P) 273000 U B02BD02 Human coagulation factor VIII(P) 3261500 U B02BD03 Factor VIII inhibitor bypassing activity(P) 940000 U B02BD04 Human coagulation factor IX(P) 655200 U B02BD05 Human coagulation factor VII(P) 192000 U
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B02BD06 Von Willebrand factor, human+Human coagulation factor VIII(P) 2369250 U
B02BD08 Coagulation factor VIIa(P) 6350000 U B02BD10 Von Willebrand factor, human(P) 26000 U B02BD80 Turoctocog alfa(P) 50000 U B02BD81 Simoctocog alfa(P) 2248500 U B02BD83 Efmoroctocog alfa(P) 76000 U B02BX Other systemic hemostatics 0,0152 B02BX01 Etamsylate(P) 1010 g B02BX04 Romiplostim(P) 0,02 g 30 mcg 0,0014 B02BX05 Eltrombopag(O) 325,5 g 50 mg 0,0135 B02BX06 Emicizumab(P) 2,7 g 15 mg 0,0004 B03 ANTIANEMIC PREPARATIONS 24,4292 B03A IRON PREPARATIONS 4,2694 B03AA Iron bivalent, oral preparations 2,5532 B03AA07 Ferrous sulphate(O) 246957 g 0,2 g 2,5532 B03AB Iron trivalent, oral preparations B03AB80 Iron (III) hydroxide polymaltose complex(O) 82826,5 g B03AC Iron, parenteral preparations 0,0931 B03AC01 Dextriferron(P) 804,5 g 0,1 g 0,0166 B03AC02 Iron (III) hydroxide sucrose complex(P) 1409,5 g 0,1 g 0,0291 B03AC06 Iron (III)-hydroxide dextran complex(P) 1604 g 0,1 g 0,0332 B03AC80 Iron (III) isomaltoside 1000 complex(P) 685 g 0,1 g 0,0142 B03AD Iron in combination with folic acid 1,6231 B03AD02 Ferrous fumarate+Folic acid(O) 596310 pieces 1 pieces 1,2330 B03AD03 Ferrous sulphate+Folic acid(O) 188650 pieces 1 pieces 0,3901 B03AE Iron in other combinations
B03AE81 Ferrous gluconate+Manganese gluconate+Copper gluconate(O) 1680000 ml
B03AE82 Ferrous fumarate+Folic acid+Ascorbic acid(O) 52270 pieces B03B VITAMIN B12 AND FOLIC ACID 19,2386 B03BA Vitamin B12 (cyanocobalamin and analogues) 6,5241 B03BA01 Cyanocobalamin(O) 11,25 g 1 mg 0,0233 B03BA01 Cyanocobalamin(P) 62,69 g 0,02 mg 6,4813 B03BA03 Hydroxocobalamin(P) 0,189 g 0,02 mg 0,0195 B03BB Folic acid and derivatives 12,7145 B03BB01 Folic acid(O) 2459,625 g 0,4 mg 12,7145 B03X OTHER ANTIANEMIC PREPARATIONS 0,9213 B03XA Other antianemic preparations 0,9213 B03XA02 Darbepoetin alfa(P) 1,4251 g 0,0045 mg 0,6548 B03XA03 Methoxy polyethylene glycol-epoetin beta(P) 0,3031 g 4 mcg 0,1567 B03XA80 Epoetin beta(P) 53100000 U 1000 U 0,1098 B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS B05A BLOOD AND RELATED PRODUCTS B05AA Blood substitutes and plasma protein fractions B05AA01 Albumin(P) 635690 g B05AA06 Gelatin agents(P) 9215000 ml B05AA80 Hydroxyethyl starch+Sodium chloride(P) 16000 ml B05AA81 Dextran+Sodium chloride(P) 45500 ml
B05AA83 Gelatine+Sodium chloride+Potassium chloride+Magnesium chloride+Sodium lactate(P)
357500 ml
B05AA86 human plasma proteins(P) 242000 ml B05B I.V. SOLUTIONS B05BA Solutions for parenteral nutrition B05BA01 Amino acids(P) 646900 ml B05BA02 Fat emulsions(P) 166000 ml B05BA03 Carbohydrates(P) 4000 g B05BA03 Carbohydrates(P) 71342500 ml B05BA10 Combinations(P) 15803944 ml B05BB Solutions affecting the electrolyte balance
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day B05BB01 Electrolytes(P) 172929500 ml B05BB03 Trometamol(P) 200 ml B05BC Solutions producing osmotic diuresis B05BC01 Mannitol(P) 906000 ml B05C IRRIGATING SOLUTIONS B05CX Other irrigating solutions B05CX10 Combinations(NA) 216000 ml B05D PERITONEAL DIALYTICS B05DA Isotonic solutions B05DA80 Isotonic solutions(P) 8390000 ml B05DB Hypertonic solutions B05DB80 hypertonic solutions(P) 142416000 ml
B05DB81 Amino acids+Sodium chloride+Calcium chloride dihydrate+Magnesium chloride hexahydrate+Sodium lactate(P)
570000 ml
B05Z HEMODIALYTICS AND HEMOFILTRATES B05ZB Hemofiltrates
B05ZB80 Sodium chloride+Potassium chloride+Calcium chloride dihydrate+Magnesium chloride+Glucose+Sodium hydrogen carbonate(P)
21960000 ml
B05ZB82 Calcium chloride dihydrate+Magnesium chloride hexahydrate+Sodium chloride+Sodium hydrogen carbonate+Potassium chloride+Disodium phosphate dihydrate(P)
13690000 ml
B05ZB84 Calcium chloride dihydrate+Magnesium chloride hexahydrate+Lactic acid+Sodium hydrogen carbonate+Sodium chloride(P)
780000 ml
B05ZB85 Sodium citrate+Sodium chloride(P) 2429000 ml
B05ZB86 Magnesium chloride hexahydrate+Sodium chloride+Potassium chloride+Disodium phosphate dihydrate+Sodium hydrogen carbonate(P)
1340000 ml
B05X I.V. SOLUTION ADDITIVES B05XA Electrolyte solutions B05XA01 Potassium chloride(P) 975 g B05XA01 Potassium chloride(P) 3432400 ml B05XA02 Sodium hydrogen carbonate(P) 1540500 ml B05XA03 Sodium chloride(P) 494726200 ml B05XA05 Magnesium sulphate(P) 418300 ml B05XA06 Potassium dihydrogen phosphate(P) 400 ml B05XA07 Calcium chloride(P) 242600 ml B05XA14 Sodium glycerophosphate, hydrated(P) 100200 ml B05XA80 Electrolytes(P) 112700 ml B05XB Amino acids B05XB01 Arginine(P) 3100 ml B05XB02 Alanyl glutamine(P) 39500 ml B05XC Vitamins B05XC80 Vitamins(P) 848,12 g B05XC80 Vitamins(P) 221500 ml B06 OTHER HEMATOLOGICAL AGENTS 0,0006 B06A OTHER HEMATOLOGICAL AGENTS 0,0006 B06AC Drugs usedin hereditary angioedema 0,0006 B06AC01 C1-inhibitor(P) 106000 U 1400 U 0,0002 B06AC02 Icatibant(P) 3,18 g 0,03 g 0,0002 B06AC04 Conestat alfa(P) 302400 U 3500 U 0,0002 C CARDIOVASCULAR SYSTEM 429,8975 C01 CARDIAC THERAPY 23,3946 C01A CARDIAC GLYCOSIDES 2,4668 C01AA Digitalis glycosides 2,4668 C01AA05 Digoxin(O) 295,775 g 0,25 mg 2,4463 C01AA05 Digoxin(P) 2,4625 g 0,25 mg 0,0204
8/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day C01AA06 Lanatoside C(O) 0,045 g 0,001 g 0,0001 C01B ANTIARRHYTHMICS, CLASS I AND III 5,7179 C01BA Antiarrhythmics, class Ia C01BA13 Hydroquinidine(O) 252 g C01BB Antiarrhythmics, class Ib 0,0236 C01BB02 Mexiletine(O) 120 g 0,8 g 0,0003 C01BB80 Aethacizin(O) 2250 g 0,2 g 0,0233 C01BC Antiarrhythmics, class Ic 3,7064 C01BC03 Propafenone(O) 517383 g 0,3 g 3,5660 C01BC03 Propafenone(P) 568,75 g 0,3 g 0,0039 C01BC04 Flecainide(O) 13178 g 0,2 g 0,1362 C01BC04 Flecainide(P) 24 g 0,2 g 0,0002 C01BD Antiarrhythmics, class III 1,9879 C01BD01 Amiodarone(O) 185604 g 0,2 g 1,9189 C01BD01 Amiodarone(P) 5508,75 g 0,2 g 0,0570 C01BD07 Dronedarone(O) 4656 g 0,8 g 0,0120 C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES 0,8703 C01CA Adrenergic and dopaminergic agents 0,8692 C01CA01 Etilefrine(O) 3,825 g 0,05 g 0,0002 C01CA02 Isoprenaline(P) 0,537 g 0,09 g <0,0001 C01CA03 Norepinephrine(P) 330,244 g 0,006 g 0,1138 C01CA04 Dopamine(P) 1327 g 0,5 g 0,0055 C01CA06 Phenylephrine(P) 230,7 g 0,004 g 0,1193 C01CA07 Dobutamine(P) 772,5 g 0,5 g 0,0032 C01CA17 Midodrine(O) 4,375 g 0,03 g 0,0003 C01CA24 Epinephrine(I) 3,834 g C01CA24 Epinephrine(P) 140,712 g 0,5 mg 0,5819 C01CA26 Ephedrine(P) 1090,75 g 0,05 g 0,0451 C01CE Phosphodiesterase inhibitors 0,0006 C01CE02 Milrinone(P) 14,88 g 0,05 g 0,0006 C01CX Other cardiac stimulants 0,0004 C01CX08 Levosimendan(P) 2,25 g 11 mg 0,0004 C01CX80 Ammonia(I) 1162880 ml C01D VASODILATORS USED IN CARDIAC DISEASES 6,2037 C01DA Organic nitrates 6,2008 C01DA02 Glyceryl trinitrate(P) 224,1 g C01DA02 Glyceryl trinitrate(SL) 511,128 g 0,0025 g 0,4227 C01DA08 Isosorbide dinitrate(O) 9764 g 0,06 g 0,3365 C01DA08 Isosorbide dinitrate(SL) 258,75 g 0,02 g 0,0268 C01DA14 Isosorbide mononitrate(O) 104750,2 g 0,04 g 5,4148 C01DX Other vasodilatators used in cardiac diseases 0,0029 C01DX80 Meldonium(O) 1050 g 0,75 g 0,0029 C01E OTHER CARDIAC PREPARATIONS 8,1360 C01EA Prostaglandins 0,0003 C01EA01 Alprostadil(P) 0,0644 g 0,5 mg 0,0003 C01EB Other cardiac preparations 8,1357 C01EB10 Adenosine(P) 92,312 g 0,015 g 0,0127 C01EB15 Trimetazidine(O) 149704,8 g 0,04 g 7,7387 C01EB16 Ibuprofen(P) 0,92 g 0,03 g 0,0001 C01EB17 Ivabradine(O) 1590,12 g 0,01 g 0,3288 C01EB18 Ranolazine(O) 39690 g 1,5 g 0,0547 C01EB21 Regadenoson(P) 0,148 g 0,4 mg 0,0008 C01EB80 Hawthorn berry(O) 92720 ml C02 ANTIHYPERTENSIVES 3,7643 C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING 2,4247 C02AC Imidazoline receptor agonists 2,4247 C02AC01 Clonidine(O) 5,025 g 0,45 mg 0,0231 C02AC01 Clonidine(P) 3,901 g 0,45 mg 0,0179 C02AC05 Moxonidine(O) 345,8476 g 0,3 mg 2,3837 C02C ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING 1,3058
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day C02CA Alpha-adrenoreceptor antagonists 1,3058 C02CA01 Prazosin(O) 2,91 g 0,005 g 0,0012 C02CA04 Doxazosin(O) 2523,652 g 0,004 g 1,3046 C02D ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON 0,0007 C02DD Nitroferricyanide derivatives 0,0007 C02DD01 Sodium nitroprusside(P) 16 g 0,05 g 0,0007 C02K OTHER ANTIHYPERTENSIVES 0,0331 C02KX Antihypertensives for pulmonary arterial hypertension 0,0331 C02KX01 Bosentan(O) 1225 g 0,25 g 0,0101 C02KX02 Ambrisentan(O) 42,75 g 7,5 mg 0,0118 C02KX04 Macitentan(O) 3 g 10 mg 0,0006 C02KX05 Riociguat(O) 23,058 g 4,5 mg 0,0106 C03 DIURETICS 26,1197 C03A LOW-CEILING DIURETICS, THIAZIDES 1,4557 C03AA Thiazides, plain 1,4557 C03AA03 Hydrochlorothiazide(O) 17600,5 g 0,025 g 1,4557 C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES 2,3798 C03BA Sulfonamides, plain 2,3798 C03BA11 Indapamide(O) 2877,285 g 2,5 mg 2,3798 C03C HIGH-CEILING DIURETICS 18,9909 C03CA Sulfonamides, plain 18,9909 C03CA01 Furosemide(O) 72206,2 g 0,04 g 3,7326 C03CA01 Furosemide(P) 5071,8 g 0,04 g 0,2622 C03CA04 Torasemide(O) 108268,65 g 0,015 g 14,9246 C03CA04 Torasemide(P) 519,4 g 0,015 g 0,0716 C03D POTASSIUM-SPARING AGENTS 3,2787 C03DA Aldosterone antagonists 3,2787 C03DA01 Spironolactone(O) 118923,75 g 0,075 g 3,2787
C03E DIURETICS AND POTASSIUM-SPARING AGENTS IN COMBINATION
0,0146
C03EA Low-ceiling diuretics and potassium-sparing agents 0,0146 C03EA81 Hydrochlorothiazide+Amiloride(O) 7050 pieces 1 pieces 0,0146 C04 PERIPHERAL VASODILATORS 2,6811 C04A PERIPHERAL VASODILATORS 2,6811 C04AC Nicotinic acid and derivatives 0,0002 C04AC01 Nicotinic acid(P) 15 g 0,2 g 0,0002 C04AD Purine derivatives 1,7456 C04AD02 Xantinol nicotinate(O) 297 g 0,9 g 0,0007 C04AD03 Pentoxifylline(O) 842104 g 1 g 1,7412 C04AD03 Pentoxifylline(P) 528 g 0,3 g 0,0036 C04AX Other peripheral vasodilators 0,9353 C04AX21 Naftidrofuryl(O) 271415 g 0,6 g 0,9353 C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids C05AA82 Hydrocortisone+Cinchocaine(R) 58620 pieces C05AA84 Fluocortolone+Lidocaine(R) 186520 pieces C05AA84 Fluocortolone+Lidocaine(R) 187095 g C05AE Muscle relaxants C05AE01 Glyceryl trinitrate(R) 30 g
C05AX Other agents for treatment of hemorrhoids and anal fissures for topical use
C05AX81 Xeroformium+Zinc sulphate+Extract of Belladonna(R) 2230 pieces C05AX83 Yeast cell extract+Shark liver oil(R) 25 g C05AX83 Yeast cell extract+Shark liver oil(R) 307452 pieces C05AX85 Hippopheae oleum(R) 30 pieces C05B ANTIVARICOSE THERAPY C05BA Heparins or heparinoids for topical use C05BA01 Chondroitin polysulfate(C) 51360 g
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day C05BA03 Heparin sodium(C) 7751250 g C05BB Sclerosing agents for local injection C05BB02 Lauromacrogol 400(P) 96,9 g C05C CAPILLARY STABILIZING AGENTS C05CA Bioflavonoids C05CA01 Rutoside(O) 249885 pieces C05CA03 Diosmin(O) 331950 g C05CA04 Troxerutin(C) 3455980 g C05CA04 Troxerutin(O) 212160 g C05CA53 Diosmin+Hesperidine(O) 2220 pieces C07 BETA BLOCKING AGENTS 55,1998 C07A BETA BLOCKING AGENTS 55,1988 C07AA Beta blocking agents, non-selective 1,7930 C07AA05 Propranolol(O) 47315,5 g 0,16 g 0,6115 C07AA07 Sotalol(O) 91423,2 g 0,16 g 1,1815 C07AB Beta blocking agents, selective 52,7835 C07AB02 Metoprolol(O) 1907206,1 g 0,15 g 26,2904 C07AB02 Metoprolol(P) 97,6 g 0,15 g 0,0013 C07AB03 Atenolol(O) 19616,25 g 0,075 g 0,5408 C07AB07 Bisoprolol(O) 14796,3 g 0,01 g 3,0595 C07AB09 Esmolol(P) 0,5 g 2,5 g <0,0001 C07AB12 Nebivolol(O) 55354,51 g 0,005 g 22,8915 C07AG Alpha and beta blocking agents 0,6223 C07AG01 Labetalol(O) 27925 g 0,6 g 0,0962 C07AG01 Labetalol(P) 1097,5 g 0,6 g 0,0038 C07AG02 Carvedilol(O) 9471,5625 g 0,0375 g 0,5223 C07B BETA BLOCKING AGENTS AND THIAZIDES 0,0010 C07BB Beta blocking agents, selective, and thiazides 0,0010 C07BB07 Bisoprolol+Hydrochlorothiazide(O) 480 pieces 1 pieces 0,0010 C08 CALCIUM CHANNEL BLOCKERS 46,5513
C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
44,9857
C08CA Dihydropyridine derivatives 44,9857 C08CA01 Amlodipine(O) 61417,5 g 0,005 g 25,3988 C08CA02 Felodipine(O) 6751,5 g 0,005 g 2,7920 C08CA05 Nifedipine(O) 16632,24 g 0,03 g 1,1464 C08CA06 Nimodipine(O) 459 g 0,3 g 0,0032 C08CA06 Nimodipine(P) 3,75 g 0,05 g 0,0002 C08CA08 Nitrendipine(O) 45226,74 g 0,02 g 4,6758 C08CA09 Lacidipine(O) 6492,976 g 0,004 g 3,3564 C08CA13 Lercanidipine(O) 36818,1 g 0,01 g 7,6129
C08D SELECTIVE CALCIUM CHANNEL BLOCKERS WITH DIRECT CARDIAC EFFECTS
1,5656
C08DA Phenylalkylamine derivatives 1,4753 C08DA01 Verapamil(O) 171228 g 0,24 g 1,4752 C08DA01 Verapamil(P) 12,65 g 0,24 g 0,0001 C08DB Benzothiazepine derivatives 0,0902 C08DB01 Diltiazem(O) 10474,2 g 0,24 g 0,0902 C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM 203,0954 C09A ACE INHIBITORS, PLAIN 75,3170 C09AA ACE inhibitors, plain 75,3170 C09AA01 Captopril(O) 942,5 g 0,05 g 0,0390 C09AA02 Enalapril(O) 43829,85 g 0,01 g 9,0628 C09AA02 Enalapril(P) 9,3625 g 0,01 g 0,0019 C09AA03 Lisinopril(O) 0,56 g 0,01 g 0,0001 C09AA04 Perindopril(O) 12741,54 g 0,004 g 6,5865 C09AA05 Ramipril(O) 65538,64 g 2,5 mg 54,2062 C09AA09 Fosinopril(O) 38351,6 g 0,015 g 5,2867 C09AA10 Trandolapril(O) 129,528 g 0,002 g 0,1339 C09B ACE INHIBITORS, COMBINATIONS 53,2135
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day C09BA ACE inhibitors and diuretics 28,4447 C09BA02 Enalapril+Hydrochlorothiazide(O) 3166190 pieces 1 pieces 6,5468 C09BA04 Perindopril+Indapamide(O) 8714640 pieces 1 pieces 18,0194 C09BA05 Ramipril+Hydrochlorothiazide(O) 1251870 pieces 1 pieces 2,5885 C09BA09 Fosinopril+Hydrochlorothiazide(O) 623854 pieces 1 pieces 1,2900 C09BB ACE inhibitors and calcium channel blockers 11,6784 C09BB03 Lisinopril+Amlodipine(O) 826200 pieces 1 pieces 1,7083 C09BB04 Perindopril+Amlodipine(O) 3760440 pieces 1 pieces 7,7755 C09BB07 Ramipril+Amlodipine(O) 715620 pieces 1 pieces 1,4797 C09BB10 Trandolapril+Verapamil(O) 345716 pieces 1 pieces 0,7148 C09BX ACE inhibitors, other combinations 13,0905 C09BX01 Perindopril+Amlodipine+Indapamide(O) 6330870 pieces 1 pieces 13,0905 C09C ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS), PLAIN 43,0625 C09CA Angiotensin II receptor blockers (ARBs), plain 43,0625 C09CA01 Losartan(O) 94693,7 g 0,05 g 3,9160 C09CA02 Eprosartan(O) 1226,4 g 0,6 g 0,0042 C09CA03 Valsartan(O) 157357,76 g 0,08 g 4,0671 C09CA06 Candesartan(O) 39225,568 g 0,008 g 10,1384 C09CA07 Telmisartan(O) 426417,76 g 0,04 g 22,0428 C09CA08 Olmesartan medoxomil(O) 27991,88 g 0,02 g 2,8940
C09D ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS), COMBINATIONS 31,5023
C09DA Angiotensin II receptor blockers (ARBs) and diuretics 14,7201 C09DA01 Losartan+Hydrochlorothiazide(O) 939154 pieces 1 pieces 1,9419 C09DA03 Valsartan+Hydrochlorothiazide(O) 825356 pieces 1 pieces 1,7066 C09DA06 Candesartan+Hydrochlorothiazide(O) 1044152 pieces 1 pieces 2,1590 C09DA07 Telmisartan+Hydrochlorothiazide(O) 4056654 pieces 1 pieces 8,3880 C09DA08 Olmesartan medoxomil+Hydrochlorothiazide(O) 253680 pieces 1 pieces 0,5245
C09DB Angiotensin II receptor blockers (ARBs) and calcium channel blockers 12,4258
C09DB01 Valsartan+Amlodipine(O) 154244 pieces 1 pieces 0,3189 C09DB02 Olmesartan medoxomil+Amlodipine(O) 2631132 pieces 1 pieces 5,4404 C09DB04 Telmisartan+Amlodipine(O) 3157952 pieces 1 pieces 6,5298 C09DB07 Candesartan+Amlodipine(O) 66080 pieces 1 pieces 0,1366 C09DX Angiotensin II receptor blockers (ARBs), other combinations 4,3564 C09DX01 Valsartan+Amlodipine+Hydrochlorothiazide(O) 2352 pieces 1 pieces 0,0049 C09DX03 Olmesartan medoxomil+Amlodipine+Hydrochlorothiazide(O) 1914808 pieces 1 pieces 3,9593 C09DX04 Valsartan+Sacubitril(O) 189728 pieces 1 pieces 0,3923 C10 LIPID MODIFYING AGENTS 69,0915 C10A LIPID MODIFYING AGENTS, PLAIN 67,6265 C10AA HMG CoA reductase inhibitors 66,5854 C10AA01 Simvastatin(O) 72665,36 g 0,03 g 5,0084 C10AA03 Pravastatin(O) 4533 g 0,03 g 0,3124 C10AA04 Fluvastatin(O) 15646,4 g 0,06 g 0,5392 C10AA05 Atorvastatin(O) 244735,5 g 0,02 g 25,3022 C10AA07 Rosuvastatin(O) 171315,16 g 0,01 g 35,4231 C10AB Fibrates 0,6214 C10AB05 Fenofibrate(O) 60108 g 0,2 g 0,6214 C10AC Bile acid sequestrants 0,0018 C10AC01 Colestyramine(O) 10000 g 14 g 0,0015 C10AC04 Colesevelam(O) 562,5 g 3,75 g 0,0003 C10AX Other lipid modifying agents 0,4179 C10AX09 Ezetimibe(O) 1964,76 g 0,01 g 0,4063 C10AX13 Evolocumab(P) 37,94 g 10 mg 0,0078 C10AX14 Alirocumab(P) 9,9 g 5,4 mg 0,0038 C10AX80 Omega-3-acid ethyl esters 90(O) 174692 pieces C10B LIPID MODIFYING AGENTS, COMBINATIONS 1,4650
C10BA HMG CoA reductase inhibitors in combination with other lipid modifying agents
0,6065
C10BA06 Rosuvastatin+Ezetimibe(O) 293310 pieces 1 pieces 0,6065
12/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day C10BX HMG CoA reductase inhibitors, other combinations 0,8585 C10BX03 Atorvastatin+Amlodipine(O) 170280 pieces 1 pieces 0,3521 C10BX11 Atorvastatin+Amlodipine+Perindopril(O) 235410 pieces 1 pieces 0,4868 C10BX15 Atorvastatin+Perindopril(O) 9510 pieces 1 pieces 0,0197 D DERMATOLOGICALS 1,8669 D01 ANTIFUNGALS FOR DERMATOLOGICAL USE 1,2267 D01A ANTIFUNGALS FOR TOPICAL USE D01AC Imidazole and triazole derivatives D01AC01 Clotrimazole(C) 200 ml D01AC01 Clotrimazole(C) 662762,2 g D01AC05 Isoconazole(C) 224100 g D01AC08 Ketoconazole(C) 419839,8 g D01AC08 Ketoconazole(C) 1463040 ml D01AC80 Isoconazole+Diflucortolone(C) 530370 g D01AC81 Clotrimazole+Hexamidine(C) 149040 g D01AE Other antifungals for topical use D01AE14 Ciclopirox(C) 4613,4 ml D01AE15 Terbinafine(C) 630651 g D01AE16 Amorolfine(C) 20 g D01AE16 Amorolfine(C) 29172,5 ml D01AE22 Naftifine(C) 216310 ml D01AE22 Naftifine(C) 290235 g D01B ANTIFUNGALS FOR SYSTEMIC USE 1,2267 D01BA Antifungals for systemic use 1,2267 D01BA01 Griseofulvin(O) 585 g 0,5 g 0,0024 D01BA02 Terbinafine(O) 148024,5 g 0,25 g 1,2243 D02 EMOLLIENTS AND PROTECTIVES D02A EMOLLIENTS AND PROTECTIVES D02AB Zinc products D02AB80 Zinc oxide(C) 409860 g D02AE Carbamide products D02AE01 Urea(C) 109450 g D02AF Salicylic acid preparations D02AF81 Salicylic acid+Lactic acid(C) 15 ml D02B PROTECTIVES AGAINST UV-RADIATION D02BA Protectives against UV-radiation for topical use D02BA01 4-Aminobenzoic acid(O) 14160 g D03 PREPARATIONS FOR TREATMENT OF WOUNDS AND ULCERS D03A CICATRIZANTS D03AX Other cicatrizants D03AX03 Dexpanthenol(C) 4235255 g D03AX81 Heparin sodium+Allantoin+Extract of Cepae(C) 129420 g D03AX83 Dexpanthenol+Chlorhexidine(C) 1952130 g D05 ANTIPSORIATICS 0,0536 D05A ANTIPSORIATICS FOR TOPICAL USE D05AA Tars D05AA85 Coal tar+Salicylic acid(C) 315400 ml D05AC Antracen derivatives D05AC01 Dithranol(C) 1500 g D05AX Other antipsoriatics for topical use D05AX02 Calcipotriol(C) 210 g D05AX80 Calcipotriol+Betamethasone(C) 822210 g D05B ANTIPSORIATICS FOR SYSTEMIC USE 0,0536 D05BB Retinoids for treatment of psoriasis 0,0536 D05BB02 Acitretin(O) 906,9 g 0,035 g 0,0536
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE D06AA Tetracycline and derivatives D06AA04 Tetracycline(C) 3035 g
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day D06AX Other antibiotics for topical use D06AX01 Fusidic acid(C) 212160 g D06AX02 Chloramphenicol(C) 375 g D06AX09 Mupirocin(C) 4335 g D06AX80 Bacitracin+Neomycin(C) 170440 g D06AX84 Chloramphenicol+Methyluracil(C) 1600 g D06B CHEMOTHERAPEUTICS FOR TOPICAL USE D06BA Sulfonamides D06BA01 Silver sulfadiazine(C) 1528200 g D06BB Antivirals D06BB03 Aciclovir(C) 257101 g D06BB04 Podophyllotoxin(C) 2826 ml D06BB06 Penciclovir(C) 4084 g D06BB10 Imiquimod(C) 3160 g D06BX Other chemotherapeutics D06BX01 Metronidazole (C) 136960 g D06BX02 Ingenol mebutate(C) 0,0002 g D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS D07A CORTICOSTEROIDS, PLAIN D07AA Corticosteroids, weak (group I) D07AA02 Hydrocortisone(C) 632620 g D07AB Corticosteroids, moderately potent (group II) D07AB09 Triamcinolone(C) 40290 g D07AC Corticosteroids, potent (group III) D07AC01 Betamethasone(C) 151155 g D07AC04 Fluocinolone acetonide(C) 30 g D07AC13 Mometasone(C) 325780 ml D07AC13 Mometasone(C) 1162600 g D07AC14 Methylprednisolone aceponate(C) 577100 g D07AC17 Fluticasone(C) 56400 g D07AD Corticosteroids, very potent (group IV) D07AD01 Clobetasol(C) 91200 ml D07AD01 Clobetasol(C) 935425 g D07B CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS D07BA Corticosteroids, weak, combinations with antiseptics D07BA80 Hydrocortisone+Chlorhexidine(C) 367740 g D07BC Corticosteroids, potent, combinations with antiseptics D07BC80 Betamethasone+Salicylic acid(C) 5105 g D07BC80 Betamethasone+Salicylic acid(C) 909000 ml D07C CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS D07CA Corticosteroids, weak, combinations with antibiotics D07CA83 Hydrocortisone+Fusidic acid(C) 82290 g D07CC Corticosteroids, potent, combinations with antibiotics D07CC80 Betamethasone+Fusidic acid(C) 522780 g D07CC83 Betamethasone+Gentamicin(C) 200 g D07X CORTICOSTEROIDS, OTHER COMBINATIONS D07XA Corticosteroids, weak, other combinations D07XA81 Prednisolone+Salicylic acid(C) 199500 ml D07XC Corticosteroids, potent, other combinations D07XC03 Mometasone+Salicylic acid(C) 10350 g D08 ANTISEPTICS AND DISINFECTANTS D08A ANTISEPTICS AND DISINFECTANTS D08AG Iodine products D08AG02 Povidone, iodinated(C) 969130 ml D08AG02 Povidone, iodinated(C) 3450150 g D08AG03 Iodine(C) 795620 ml D08AJ Quaternary ammonium compounds D08AJ81 Octenidine+Phenoxyethanol(C) 9997450 ml D08AX Other antiseptics and disinfectants D08AX82 Tar+Castor oil+Xeroformium(C) 9960 g
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day D08AX83 Brilliant Green(C) 286130 ml D10 ANTI-ACNE PREPARATIONS 0,5178 D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE D10AD Retinoids for topical use in acne D10AD01 Tretinoin(C) 30570 g D10AD03 Adapalene(C) 134130 g D10AD80 Adapalene+Benzoyl peroxide(C) 25410 g D10AD81 Tretinoin+Erythromycin(C) 58080 g D10AF Antiinfectives for treatment of acne D10AF02 Erythromycin(C) 256900 ml D10AF81 Clindamycin+Benzoyl peroxide(C) 301575 g D10AF82 Clindamycin+Tretinoin(C) 150720 g D10AX Other anti-acne preparations for topical use D10AX03 Azelaic acid(C) 262410 g D10B ANTI-ACNE PREPARATIONS FOR SYSTEMIC USE 0,5178 D10BA Retinoids for treatment of acne 0,5178 D10BA01 Isotretinoin(O) 7513,2 g 0,03 g 0,5178 D11 OTHER DERMATOLOGICAL PREPARATIONS 0,0687 D11A OTHER DERMATOLOGICAL PREPARATIONS 0,0687 D11AH Agents for dermatitis, excluding corticosteroids 0,0064 D11AH01 Tacrolimus(C) 56700 g D11AH02 Pimecrolimus(C) 196500 g D11AH05 Dupilumab(P) 66 g 21,4 mg 0,0064 D11AX Other dermatologicals 0,0624 D11AX01 Minoxidil(C) 93600 ml D11AX10 Finasteride(O) 30,156 g 0,001 g 0,0624 D11AX16 Eflornithine(C) 210 g D11AX22 Ivermectin(C) 71700 g D11AX82 Hydroquinone+Fluocinolone acetonide+Tretinoin(C) 30 g G GENITO URINARY SYSTEM AND SEX HORMONES 56,5981 G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS 0,9380
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
0,9380
G01AA Antibiotics 0,1489 G01AA10 Clindamycin(V) 7200,7 g 0,1 g 0,1489 G01AA80 Nystatin+Neomycin+Polymyxin B(V) 60 pieces G01AC Quinoline derivatives 0,0431 G01AC05 Dequalinium(V) 417,3 g 20 mg 0,0431 G01AF Imidazole derivatives 0,7460 G01AF01 Metronidazole (V) 12514 g 0,5 g 0,0518 G01AF02 Clotrimazole(V) 28968,8 g 0,1 g 0,5990 G01AF05 Econazole(V) 4606,2 g 0,1 g 0,0952 G02 OTHER GYNECOLOGICALS 4,3078 G02A UTEROTONICS 0,0956 G02AB Ergot alkaloids 0,0018 G02AB01 Methylergometrine(P) 0,1738 g 0,2 mg 0,0018 G02AD Prostaglandins 0,0938 G02AD02 Dinoprostone(P) 0,46 g G02AD02 Dinoprostone(V) 2,0649 g 0,5 mg 0,0085 G02AD06 Misoprostol(O) 8,2488 g 0,2 mg 0,0853 G02B CONTRACEPTIVES FOR TOPICAL USE 2,6245 G02BA Intrauterine contraceptives 0,0190 G02BA03 Levonorgestrel(V) 9176 pieces 1 pieces 0,0190 G02BB Intravaginal contraceptives 2,6055 G02BB01 Etonogestrel+Ethinylestradiol(V) 44021 pieces 0,036 pieces 2,5284 G02BB81 Benzalkonium chloride(V) 37300 pieces 1 pieces 0,0771 G02BB81 Benzalkonium chloride(V) 48240 g G02C OTHER GYNECOLOGICALS 1,5877 G02CA Sympathomimetics, labour repressants G02CA80 Hexoprenaline(P) 0,0222 g
15/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day G02CB Prolactine inhibitors 0,1534 G02CB01 Bromocriptine(O) 308,05 g 0,005 g 0,1274 G02CB03 Cabergoline(O) 6,3 g 0,5 mg 0,0261 G02CX Other gynecologicals 1,4342 G02CX01 Atosiban(P) 0,9375 g 0,165 g <0,0001 G02CX03 Agni casti fructus(O) 396270 pieces 1 pieces 0,8194 G02CX04 Cimicifugae rhizoma(O) 594690 pieces 2 pieces 0,6148
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM 31,9661
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE 25,5811 G03AA Progestogens and estrogens, fixed combinations 20,5113 G03AA07 Levonorgestrel+Ethinylestradiol(O) 174027 pieces 1 pieces 0,3598 G03AA09 Desogestrel+Ethinylestradiol(O) 471996 pieces 0,75 pieces 1,3013 G03AA10 Gestodene+Ethinylestradiol(O) 24164 pieces 1 pieces 0,0500 G03AA10 Gestodene+Ethinylestradiol(O) 2257689 pieces 0,75 pieces 6,2244 G03AA12 Drospirenone+Ethinylestradiol(O) 1144052 pieces 1 pieces 2,3656 G03AA12 Drospirenone+Ethinylestradiol(O) 1887102 pieces 0,75 pieces 5,2027 G03AA13 Norelgestromin+Ethinylestradiol(TD) 93681 pieces 0,107 pieces 1,8103 G03AA15 Chlormadinone+Ethinylestradiol(O) 184716 pieces 0,75 pieces 0,5093 G03AA16 Dienogest+Ethinylestradiol(O) 361200 pieces 1 pieces 0,7469 G03AA16 Dienogest+Ethinylestradiol(O) 704109 pieces 0,75 pieces 1,9412 G03AB Progestogens and estrogens, sequential preparations 0,1749 G03AB05 Desogestrel+Ethinylestradiol(O) 4092 pieces 0,75 pieces 0,0113 G03AB08 Dienogest+Estradiol valerate(O) 79128 pieces 1 pieces 0,1636 G03AC Progestogens 4,8117 G03AC08 Etonogestrel(P) 66,572 g 68 mcg 2,0243 G03AC09 Desogestrel(O) 1348060 pieces 1 pieces 2,7874 G03AD Emergency contraceptives 0,0832 G03AD01 Levonorgestrel(O) 58,026 g 1,5 mg 0,0800 G03AD02 Ulipristal(O) 46,65 g 0,03 g 0,0032 G03B ANDROGENS 0,2302 G03BA 3-oxoandrosten (4) derivatives 0,2302 G03BA03 Testosterone(C) 22,5 g 0,05 g 0,0009 G03BA03 Testosterone(O) 7,2 g 0,12 g 0,0001 G03BA03 Testosterone(P) 1994,25 g 0,018 g 0,2291 G03BA03 Testosterone(TD) 2,576 g 0,05 g 0,0001 G03C ESTROGENS 1,6383 G03CA Natural and semisynthetic estrogens, plain 1,6328 G03CA03 Estradiol(C, V) 106075 g G03CA03 Estradiol(O) 774,816 g 2 mg 0,8011 G03CA03 Estradiol(TD) 0,0336 g 0,05 mg 0,0014 G03CA03 Estradiol(TD) 21,3343 g 1,53 mg 0,0288 G03CA03 Estradiol(TD) 68,8835 g 1 mg 0,1424 G03CA03 Estradiol(V) 5,3221 g 0,025 mg 0,4402 G03CA04 Estriol(O) 0,45 g 0,002 g 0,0005 G03CA04 Estriol(V) 21,1275 g 0,2 mg 0,2184 G03CA80 Estradiol+Prednisolone(C) 77725 g G03CX Other estrogens 0,0055 G03CX01 Tibolone(O) 6,65 g 2,5 mg 0,0055 G03D PROGESTOGENS 1,4796 G03DA Pregnen (4) derivatives 0,6687 G03DA02 Medroxyprogesterone(O) 46,05 g 0,005 g 0,0190 G03DA02 Medroxyprogesterone(P) 266,055 g 0,007 g 0,0786 G03DA04 Progesterone(O) 30234 g 0,3 g 0,2084 G03DA04 Progesterone(P) 201,225 g 0,005 g 0,0832 G03DA04 Progesterone(V) 12163,95 g 0,09 g 0,2795 G03DB Pregnadien derivatives 0,8109 G03DB01 Dydrogesterone(O) 3106,6 g 0,01 g 0,6424 G03DB08 Dienogest(O) 163,016 g 2 mg 0,1685 G03F PROGESTOGENS AND ESTROGENS IN COMBINATION 2,1512
16/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day G03FA Progestogens and estrogens, fixed combinations 1,6917 G03FA01 Norethisterone+Estradiol(O) 526260 pieces 1 pieces 1,0882 G03FA14 Dydrogesterone+Estradiol(O) 116452 pieces 1 pieces 0,2408 G03FA17 Drospirenone+Estradiol(O) 175420 pieces 1 pieces 0,3627 G03FA80 Medroxyprogesterone+Estradiol(O) 168 pieces G03FB Progestogens and estrogens, sequential preparations 0,4595 G03FB05 Norethisterone+Estradiol(O) 174916 pieces 1 pieces 0,3617 G03FB08 Dydrogesterone+Estradiol(O) 47320 pieces 1 pieces 0,0978 G03G GONADOTROPINS AND OTHER OVULATION STIMULANTS 0,3838 G03GA Gonadotropins 0,1569 G03GA01 Chorionic gonadotrophin(P) 40000 U 250 U 0,0003 G03GA05 Follitropin alfa(P) 4909125 U 75 U 0,1353 G03GA07 Lutropin alfa(P) 384075 U 75 U 0,0106 G03GA08 Choriogonadotropin alfa(P) 0,9128 g 0,25 mg 0,0075 G03GA30 Follitropin alfa+Lutropin alfa(P) 1490 doses 1 doses 0,0031 G03GB Ovulation stimulants, synthetic 0,2269 G03GB02 Clomifene(O) 987,7 g 0,009 g 0,2269 G03H ANTIANDROGENS 0,4714 G03HA Antiandrogens, plain 0,1183 G03HA01 Cyproterone(O) 5722,5 g 0,1 g 0,1183 G03HB Antiandrogens and estrogens 0,3531 G03HB01 Cyproterone+Estrogen(O) 128058 pieces 0,75 pieces 0,3531
G03X OTHER SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
0,0305
G03XA Antigonadotropins and similar agents 0,0008 G03XA01 Danazol(O) 240 g 0,6 g 0,0008 G03XB Progesterone receptor modulators 0,0296 G03XB01 Mifepristone(O) 803,4 g 0,6 g 0,0028 G03XB02 Ulipristal(O) 64,96 g 5 mg 0,0269 G04 UROLOGICALS 19,3862 G04B UROLOGICALS 3,1912 G04BD Drugs for urinary frequency and incontinence 1,8302 G04BD04 Oxybutynin(O) 4754,4 g 0,015 g 0,6554 G04BD06 Propiverine(O) 8,82 g 0,03 g 0,0006 G04BD07 Tolterodine(O) 519,736 g 0,004 g 0,2687 G04BD08 Solifenacin(O) 588,6 g 0,005 g 0,2434 G04BD09 Trospium chloride(O) 3496,95 g 0,04 g 0,1808 G04BD12 Mirabegron(O) 11640 g 50 mg 0,4814 G04BE Drugs used in erectile dysfunction 1,3477 G04BE01 Alprostadil(P) 0,0722 g 0,02 mg 0,0075 G04BE01 Alprostadil(urethral) 0,006 g 0,25 mg <0,0001 G04BE03 Sildenafil(O) 24328 g 0,05 g 1,0061 G04BE08 Tadalafil(O) 1339,24 g 0,01 g 0,2769 G04BE09 Vardenafil(O) 30,72 g 0,01 g 0,0064 G04BE10 Avanafil(O) 2460 g 0,1 g 0,0509 G04BX Other urologicals 0,0133 G04BX14 Dapoxetin(O) 192,87 g 0,03 g 0,0133 G04BX80 Centaury+Lovage root+Rosemary leaf(O) 1028220 pieces G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY 16,1950 G04CA Alpha-adrenoreceptor antagonists 13,3268 G04CA01 Alfuzosin(O) 8090,4 g 7,5 mg 2,2305 G04CA02 Tamsulosin(O) 1511,76 g 0,4 mg 7,8147 G04CA04 Silodosin(O) 573,12 g 8 mg 0,1481 G04CA52 Tamsulosin+Dutasteride(O) 1515420 pieces 1 pieces 3,1335 G04CB Testosterone-5-alpha reductase inhibitors 0,5733 G04CB01 Finasteride(O) 341,05 g 0,005 g 0,1410 G04CB02 Dutasteride(O) 104,535 g 0,5 mg 0,4323 G04CX Other drugs used in benign prostatic hypertrophy 2,2949 G04CX02 Sabalis serrulatae fructus(O) 355152 g 0,32 g 2,2949
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
29,7102
H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES 0,4330
H01A ANTERIOR PITUITARY LOBE HORMONES AND ANALOGUES 0,1540 H01AA ACTH 0,0001 H01AA02 Tetracosactide(P) 0,0107 g 0,25 mg 0,0001 H01AB Thyrotropin 0,0007 H01AB01 Thyrotropin alfa(P) 0,3078 g 0,9 mg 0,0007 H01AC Somatropin and somatropin agonists 0,1364 H01AC01 Somatropin(P) 131899,5347 U 2 U 0,1364 H01AX Other anterior pituitary lobe hormones and analogues 0,0168 H01AX01 Pegvisomant(P) 81,3 g 0,01 g 0,0168 H01B POSTERIOR PITUITARY LOBE HORMONES 0,1520 H01BA Vasopressin and analogues 0,0949 H01BA01 Argipressin(P) 12600 U 40 U 0,0007 H01BA02 Desmopressin(N) 0,0383 g 0,025 mg 0,0032 H01BA02 Desmopressin(P) 0,0191 g 0,004 mg 0,0098 H01BA02 Desmopressin(SL) 9,4284 g 0,24 mg 0,0812 H01BB Oxytocin and analogues 0,0571 H01BB01 Demoxytocin(O) 1206500 U 100 U 0,0249 H01BB02 Oxytocin(P) 227900 U 15 U 0,0314 H01BB03 Carbetocin(P) 0,0348 g 0,1 mg 0,0007 H01C HYPOTHALAMIC HORMONES 0,1271 H01CA Gonadotropin-releasing hormones H01CA01 Gonadorelin(P) 0,0041 g H01CB Somatostatin and analogues 0,1057 H01CB02 Octreotide(P) 13,1715 g 0,7 mg 0,0389 H01CB03 Lanreotide(P) 84,18 g 3 mg 0,0580 H01CB05 Pasireotide(P) 5,07 g 1,2 mg 0,0087 H01CC Anti-gonadotropin-releasing hormones 0,0214 H01CC02 Cetrorelix(P) 2,5893 g 0,25 mg 0,0214 H02 CORTICOSTEROIDS FOR SYSTEMIC USE 8,7530 H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN 8,7469 H02AA Mineralocorticoids 0,1618 H02AA02 Fludrocortisone(O) 7,825 g 0,1 mg 0,1618 H02AB Glucocorticoids 8,5851 H02AB01 Betamethasone(P) 18,488 g 1,5 mg 0,0255 H02AB02 Dexamethasone(O) 833,815 g 1,5 mg 1,1494 H02AB02 Dexamethasone(P) 743,1 g 1,5 mg 1,0243 H02AB04 Methylprednisolone(O) 7413,2 g 7,5 mg 2,0438 H02AB04 Methylprednisolone(P) 5143,765 g 0,02 g 0,5318 H02AB06 Prednisolone(O) 12503 g 0,01 g 2,5853 H02AB06 Prednisolone(P) 2400,45 g 0,01 g 0,4963 H02AB08 Triamcinolone(O) 13,4 g 7,5 mg 0,0037 H02AB08 Triamcinolone(P) 1572,9 g 7,5 mg 0,4336 H02AB09 Hydrocortisone(O) 3511,15 g 0,03 g 0,2420 H02AB09 Hydrocortisone(P) 716,2 g 0,03 g 0,0494 H02B CORTICOSTEROIDS FOR SYSTEMIC USE, COMBINATIONS 0,0060 H02BX Corticosteroids for systemic use, combinations 0,0060 H02BX80 Hydrocortisone+Lidocaine(P) 87,5 g 0,03 g 0,0060 H03 THYROID THERAPY 20,4827 H03A THYROID PREPARATIONS 19,1590 H03AA Thyroid hormones 19,1590 H03AA01 Levothyroxine sodium(O) 1389,735 g 0,15 mg 19,1572 H03AA02 Liothyronine(O) 0,0528 g 0,06 mg 0,0018 H03AA03 Levothyroxine sodium+Liothyronine(O) 1500 pieces H03AA04 Tiratricol(O) 0,63 g H03B ANTITHYROID PREPARATIONS 1,3237 H03BA Thiouracils 0,1460
18/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day H03BA02 Propylthiouracil(O) 7061,8 g 0,1 g 0,1460 H03BB Sulfur-containing imidazole derivatives 1,1777 H03BB02 Thiamazole(O) 5695,5 g 0,01 g 1,1777 H03BC Perchlorates H03BC02 Sodium perchlorate(O) 24 g H04 PANCREATIC HORMONES 0,0011 H04A GLYCOGENOLYTIC HORMONES 0,0011 H04AA Glycogenolytic hormones 0,0011 H04AA01 Glucagon(P) 0,53 g 0,001 g 0,0011 H05 CALCIUM HOMEOSTASIS 0,0404 H05B ANTI-PARATHYROID AGENTS 0,0404 H05BX Other anti-parathyroid agents 0,0404 H05BX01 Cinacalcet(O) 949,2 g 0,06 g 0,0327 H05BX02 Paricalcitol(O) 0,0074 g 2 mcg 0,0077 J ANTIINFECTIVES FOR SYSTEMIC USE 19,2087 J01 ANTIBACTERIALS FOR SYSTEMIC USE 11,9736 J01A TETRACYCLINES 1,3846 J01AA Tetracyclines 1,3846 J01AA02 Doxycycline(O) 66939 g 0,1 g 1,3841 J01AA08 Minocycline(O) 7,5 g 0,2 g 0,0001 J01AA12 Tigecycline(P) 20 g 0,1 g 0,0004 J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS 4,2870 J01CA Penicillins with extended spectrum 1,6833 J01CA01 Ampicillin(P) 23700 g 6 g 0,0082 J01CA04 Amoxicillin(O) 1215205 g 1,5 g 1,6751 J01CE Beta-lactamase sensitive penicillins 0,1596 J01CE01 Benzylpenicillin(P) 34860 g 3,6 g 0,0200 J01CE02 Phenoxymethylpenicillin(O) 133958,4 g 2 g 0,1385 J01CE08 Benzathine benzylpenicillin(P) 1803,6 g 3,6 g 0,0010 J01CE80 Benzathine benzylpenicillin+Procaine benzylpenicillin(P) 34,2 g 3,6 g <0,0001 J01CF Beta-lactamase resistant penicillins 0,0976 J01CF04 Oxacillin(P) 94300 g 2 g 0,0975 J01CF05 Flucloxacillin(O) 140 g 2 g 0,0001 J01CR Combinations of penicillins, incl. beta-lactamase inhibitors 2,3465 J01CR01 Ampicillin+Sulbactam(P) 125827 g 6 g 0,0434 J01CR02 Amoxicillin+Clavulanic acid(O) 1464285,55 g 1,5 g 2,0185 J01CR02 Amoxicillin+Clavulanic acid(P) 241480 g 3 g 0,1664 J01CR04 Sultamicillin(O) 56457 g 1,5 g 0,0778 J01CR05 Piperacillin+Tazobactam(P) 273328 g 14 g 0,0404 J01D OTHER BETA-LACTAM ANTIBACTERIALS 1,6932 J01DB First-generation cephalosporins 0,2473 J01DB01 Cefalexin(O) 60 g 2 g 0,0001 J01DB04 Cefazolin(P) 105710 g 3 g 0,0729 J01DB05 Cefadroxil(O) 168641 g 2 g 0,1744 J01DC Second-generation cephalosporins 1,3172 J01DC01 Cefoxitin(P) 10452 g 6 g 0,0036 J01DC02 Cefuroxime(O) 257183 g 0,5 g 1,0636 J01DC02 Cefuroxime(P) 283935 g 3 g 0,1957 J01DC10 Cefprozil(O) 26277 g 1 g 0,0543 J01DD Third-generation cephalosporins 0,0523 J01DD01 Cefotaxime(P) 46930 g 4 g 0,0243 J01DD02 Ceftazidime(P) 13712 g 4 g 0,0071 J01DD04 Ceftriaxone(P) 19600 g 2 g 0,0203 J01DD81 Ceftazidime+Avibactam(P) 2120 g 6 g 0,0007 J01DE Fourth-generation cephalosporins 0,0101 J01DE01 Cefepime(P) 19630 g 4 g 0,0101 J01DH Carbapenems 0,0662 J01DH02 Meropenem(P) 45205 g 3 g 0,0312 J01DH03 Ertapenem(P) 10333 g 1 g 0,0214 J01DH51 Imipenem+Cilastatin(P) 13210 g 2 g 0,0137
19/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day J01DI Other cephalosporins and penems <0,0001 J01DI54 Ceftolozane+Tazobactam(P) 60 g 3 g <0,0001 J01E SULFONAMIDES AND TRIMETHOPRIM 0,4532 J01EA Trimethoprim and derivatives 0,0229 J01EA01 Trimethoprim(O) 4431 g 0,4 g 0,0229
J01EE Combinations of sulfonamides and trimethoprim, incl. derivatives 0,4303
J01EE01 Sulfamethoxazole+Trimethoprim(O) 400 pieces 4 pieces 0,0002 J01EE01 Sulfamethoxazole+Trimethoprim(O) 374500 pieces 2 pieces 0,3872 J01EE01 Sulfamethoxazole+Trimethoprim(O) 719100 ml 40 ml 0,0372 J01EE01 Sulfamethoxazole+Trimethoprim(P) 55570 ml 20 ml 0,0057 J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS 2,4893 J01FA Macrolides 2,3132 J01FA01 Erythromycin(O) 50 g 1 g 0,0001 J01FA01 Erythromycin(P) 130 g 1 g 0,0003 J01FA09 Clarithromycin(O) 417627 g 0,5 g 1,7271 J01FA09 Clarithromycin(P) 3239,5 g 1 g 0,0067 J01FA10 Azithromycin(O) 84004,4 g 0,3 g 0,5790 J01FA10 Azithromycin(P) 7 g 0,5 g <0,0001 J01FF Lincosamides 0,1761 J01FF01 Clindamycin(O) 95548,8 g 1,2 g 0,1646 J01FF01 Clindamycin(P) 10005 g 1,8 g 0,0115 J01G AMINOGLYCOSIDE ANTIBACTERIALS 0,0241 J01GB Other aminoglycosides 0,0241 J01GB01 Tobramycin(I) 100,352 g 0,112 g 0,0019 J01GB01 Tobramycin(I) 470,4 g 0,3 g 0,0032 J01GB03 Gentamicin(P) 1631,025 g 0,24 g 0,0141 J01GB06 Amikacin(P) 2415 g 1 g 0,0050 J01M QUINOLONE ANTIBACTERIALS 0,7739 J01MA Fluoroquinolones 0,7739 J01MA01 Ofloxacin(O) 3308 g 0,4 g 0,0171 J01MA02 Ciprofloxacin(O) 267965 g 1 g 0,5541 J01MA02 Ciprofloxacin(P) 12164,5 g 0,8 g 0,0314 J01MA06 Norfloxacin(O) 46536 g 0,8 g 0,1203 J01MA12 Levofloxacin(O) 3202,5 g 0,5 g 0,0132 J01MA12 Levofloxacin(P) 385 g 0,5 g 0,0016 J01MA14 Moxifloxacin(O) 6818 g 0,4 g 0,0352 J01MA14 Moxifloxacin(P) 184 g 0,4 g 0,0010 J01X OTHER ANTIBACTERIALS 0,8682 J01XA Glycopeptide antibacterials 0,0229 J01XA01 Vancomycin(P) 22075 g 2 g 0,0228 J01XA02 Teicoplanin(P) 13,6 g 0,4 g 0,0001 J01XB Polymyxins 0,0019 J01XB01 Colistin(I, P) 1740000000 U 9000000 U 0,0004 J01XB01 Colistin(P) 6430000000 U 9000000 U 0,0015 J01XC Steroid antibacterials 0,0002 J01XC01 Fusidic acid(O) 150 g 1,5 g 0,0002 J01XD Imidazole derivatives 0,2389 J01XD01 Metronidazole (O) 193175 g 2 g 0,1997 J01XD01 Metronidazole (P) 28415 g 1,5 g 0,0392 J01XE Nitrofuran derivatives 0,5830 J01XE01 Nitrofurantoin(O) 56394 g 0,2 g 0,5830 J01XX Other antibacterials 0,0213 J01XX01 Fosfomycin(O) 4881 g 3 g 0,0034 J01XX08 Linezolid(O) 8862 g 1,2 g 0,0153 J01XX08 Linezolid(P) 1482 g 1,2 g 0,0026 J01XX09 Daptomycin(P) 21 g 0,28 g 0,0002 J02 ANTIMYCOTICS FOR SYSTEMIC USE 0,3666 J02A ANTIMYCOTICS FOR SYSTEMIC USE 0,3666 J02AA Antibiotics 0,0089
20/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day J02AA01 Amphotericin(O) 315 g J02AA01 Amphotericin(P) 151,35 g 0,035 g 0,0089 J02AB Imidazole derivatives 0,0002 J02AB02 Ketoconazole(O) 20 g 0,2 g 0,0002 J02AC Triazole derivatives 0,3493 J02AC01 Fluconazole(O) 12330,4 g 0,2 g 0,1275 J02AC01 Fluconazole(P) 3068,6 g 0,2 g 0,0317 J02AC02 Itraconazole(O) 15006,2 g 0,2 g 0,1551 J02AC03 Voriconazole(O) 2446,4 g 0,4 g 0,0126 J02AC03 Voriconazole(P) 212,8 g 0,4 g 0,0011 J02AC04 Posaconazole(O) 2971,2 g 0,3 g 0,0205 J02AC05 Isavuconazole(O) 39,2 g 0,2 g 0,0004 J02AC05 Isavuconazole(P) 30,4 g 0,2 g 0,0003 J02AX Other antimycotics for systemic use 0,0081 J02AX04 Caspofungin(P) 76,95 g 0,05 g 0,0032 J02AX06 Anidulafungin(P) 240,1 g 0,1 g 0,0050 J04 ANTIMYCOBACTERIALS 0,1140 J04A DRUGS FOR TREATMENT OF TUBERCULOSIS 0,0943 J04AB Antibiotics 0,0302 J04AB01 Cycloserine(O) 7000 g 0,75 g 0,0193 J04AB02 Rifampicin(O) 3090 g 0,6 g 0,0106 J04AB02 Rifampicin(P) 84 g 0,6 g 0,0003 J04AC Hydrazides 0,0031 J04AC01 Isoniazid(O) 450 g 0,3 g 0,0031 J04AD Thiocarbamide derivatives 0,0110 J04AD01 Protionamide(O) 4000 g 0,75 g 0,0110 J04AK Other drugs for treatment of tuberculosis 0,0096 J04AK03 Terizidone(O) 137,5 g J04AK05 Bedaquiline(O) 225,6 g 86 mg 0,0054 J04AK06 Delamanid(O) 408 g 0,2 g 0,0042 J04AM Combinations of drugs for treatment of tuberculosis 0,0403 J04AM02 Rifampicin+Isoniazid(O) 12000 pieces 4 pieces 0,0062 J04AM02 Rifampicin+Isoniazid(O) 33000 pieces 2 pieces 0,0341 J04B DRUGS FOR TREATMENT OF LEPRA 0,0196 J04BA Drugs for treatment of lepra 0,0196 J04BA01 Clofazimine(O) 380 g 0,1 g 0,0079 J04BA02 Dapsone(O) 285 g 0,05 g 0,0118 J05 ANTIVIRALS FOR SYSTEMIC USE 6,7546 J05A DIRECT ACTING ANTIVIRALS 6,7546
J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors 0,3683
J05AB01 Aciclovir(O) 317568,62 g 4 g 0,1642 J05AB01 Aciclovir(P) 2950 g 4 g 0,0015 J05AB06 Ganciclovir(P) 196 g 0,5 g 0,0008 J05AB11 Valaciclovir(O) 277732 g 3 g 0,1914 J05AB14 Valganciclovir(O) 4537 g 0,9 g 0,0104 J05AD Phosphonic acid derivatives 0,0011 J05AD01 Foscarnet sodium(P) 3420 g 6,5 g 0,0011 J05AF Nucleoside and nucleotide reverse transcriptase inhibitors 0,1005 J05AF01 Zidovudine(O) 356 g 0,6 g 0,0012 J05AF01 Zidovudine(P) 25 g 0,6 g 0,0001 J05AF05 Lamivudine(O) 1210 g 0,3 g 0,0083 J05AF06 Abacavir(O) 1850,4 g 0,6 g 0,0064 J05AF07 Tenofovir disoproxil(O) 58,8 g 0,245 g 0,0005 J05AF10 Entecavir(O) 19,875 g 0,5 mg 0,0822 J05AF13 Tenofovir alafenamide(O) 21 g 25 mg 0,0017 J05AG Non-nucleoside reverse transcriptase inhibitors 0,9683 J05AG03 Efavirenz(O) 76320 g 0,6 g 0,2630 J05AG05 Rilpivirine(O) 8527,5 g 25 mg 0,7053 J05AH Neuraminidase inhibitors 0,2697
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day J05AH02 Oseltamivir(O) 19565,25 g 0,15 g 0,2697 J05AP Antivirals for treatment of HCV infections 0,1316 J05AP01 Ribavirin(O) 1013,6 g 1 g 0,0021 J05AP54 Elbasvir+Grazoprevir(O) 5208 pieces 1 pieces 0,0108 J05AP55 Sofosbuvir+Velpatasvir(O) 6188 pieces 1 pieces 0,0128 J05AP57 Glecaprevir+Pibrentasvir(O) 153720 pieces 3 pieces 0,1059 J05AR Antivirals for treatment of HIV infections, combinations 3,9775 J05AR01 Zidovudine+Lamivudine(O) 128640 pieces 2 pieces 0,1330 J05AR02 Lamivudine+Abacavir(O) 367740 pieces 1 pieces 0,7604 J05AR03 Tenofovir disoproxil+Emtricitabine(O) 783120 pieces 1 pieces 1,6193 J05AR09 Elvitegravir+Cobicistat+Emtricitabine+Tenofovir disoproxil(O) 6120 pieces 1 pieces 0,0127 J05AR13 Lamivudine+Abacavir+Dolutegravir(O) 183990 pieces 1 pieces 0,3804 J05AR14 Darunavir+Cobicistat(O) 517620 pieces 1 pieces 1,0703
J05AR18 Emtricitabine+Tenofovir alafenamide+Elvitegravir+Cobicistat(O) 720 pieces 1 pieces 0,0015
J05AX Other antivirals 0,9376 J05AX08 Raltegravir(O) 342474 g 0,8 g 0,8852 J05AX12 Dolutegravir(O) 1267,05 g 50 mg 0,0524 J06 IMMUNE SERA AND IMMUNOGLOBULINS J06A IMMUNE SERA J06AA Immune sera J06AA03 Snake venom antiserum(P) 20 pieces J06B IMMUNOGLOBULINS J06BA Immunoglobulins, normal human J06BA01 Immunoglobulins, normal human, for extravascular a(P) 10863,6 g J06BA02 Immunoglobulins, normal human, for intravascular a(P) 107765 g J06BA80 Human normal immunoglobulin(P) 500 g J06BB Specific immunoglobulins J06BB01 Human Anti-D Immunoglobulin(P) 2385000 U J06BB02 Tetanus immunoglobulin(P) 25000 U J06BB03 Varicella zoster immunoglobulin(P) 4375 U J06BB04 Hepatitis B immunoglobulin(P) 2560 U J06BB05 Rabies immunoglobulin(P) 3000 U J06BB09 Cytomegalovirus immunoglobulin(P) 70000 U J06BB16 Palivizumab(P) 60,1 g J07 VACCINES J07A BACTERIAL VACCINES J07AE Cholera vaccines J07AE01 Cholera, inactivated, whole cell(O) 20 doses J07AG Hemophilus influenzae B vaccines J07AG01 Haemophilus influenzae B, purified antigen conjugated(P) 190 doses J07AH Meningococcal vaccines
J07AH08 Meningococcus, tetravalent purified polysaccharides antigen conjugated(P)
520 doses
J07AH09 Meningococcus B, multicomponent vaccine(P) 163 doses J07AL Pneumococcal vaccines J07AL01 Pneumococcus, purified polysaccharides antigen(P) 337 doses
J07AL02 Pneumococcus, purified polysaccharides antigen conjugated(P) 2523 doses
J07AL52 Pneumococcus, purified polysaccharides antigen+Haemophilus influenzae, conjugated(P)
232 doses
J07AM Tetanus vaccines J07AM51 Tetanus toxoid+Diphtheria toxoid(P) 28872 doses J07AN Tuberculosis vaccines J07AN01 Tuberculosis, live attenuated(P) 23950 doses J07AP Typhoid vaccines J07AP03 Typhoid, purified polysaccharide antigen(P) 2112 doses J07AX Other bacterial vaccines J07AX80 Diphtheria-tetanus-pertussis(P) 18985 doses J07B VIRAL VACCINES
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day J07BA Encephalitis vaccines J07BA01 Encephalitis, tick borne, inactivated, whole virus(P) 120044 doses J07BB Influenza vaccines J07BB02 Influenza, inactivated, split virus or surface antigen(P) 167327 doses J07BC Hepatitis vaccines J07BC01 Hepatitis B, purified antigen(P) 4390 doses J07BC02 Hepatitis A, inactivated, whole virus(P) 8119 doses
J07BC80 Hepatitis A, inactivated, whole virus+Hepatitis B, purified antigen(P) 3039 doses
J07BD Measles vaccines
J07BD52 Measles, live attunated+Rubella, live attenuated+Mumps, live,attenuated(P)
49093 doses
J07BF Poliomyelitis vaccines J07BF03 Poliomyelitis, trivalent, inactivated, whole virus(P) 672 doses J07BG Rabies vaccines J07BG01 Rabies, inactivated, whole virus(P) 2446 doses J07BH Rota virus diarrhea vaccines J07BH02 Rota virus, pentavalent, live, reassorted(O) 65364 doses J07BK Varicella zoster vaccines J07BK01 Varicella, live attenuated(P) 1338 doses J07BK02 Zoster, live attenuated(P) 55 doses J07BK03 Zoster, purified antigen(P) 2 doses J07BL Yellow fever vaccines J07BL01 Yellow fever, live attenuated(P) 1836 doses J07BM Papillomavirus vaccines J07BM02 Papillomavirus (human types 16, 18)(P) 26 doses
J07BM03 Papillomavirus (human types 6, 11, 16, 18, 31, 33, 45, 52, 58)(P) 15253 doses
J07C BACTERIAL AND VIRAL VACCINES, COMBINED J07CA Bacterial and viral vaccines, combined
J07CA02 Diphtheria toxoid+Pertussis, purified antigen+Tetanus toxoid+Poliomyelitis, trivalent, inactivated, whole virus(P)
16251 doses
J07CA06 Diphtheria toxoid+Tetanus toxoid+Pertussis, purified antigen+Poliomyelitis, trivalent, inactivated, whole virus+Haemophilus influenzae B, purified antigen conjugated(P)
11167 doses
J07CA09 Diphtheria toxoid+Poliomyelitis, trivalent, inactivated, whole virus+Pertussis, purified antigen+Haemophilus influenzae B, purified antigen conjugated+Hepatitis B, purified antigen+Tetanus toxoid(P)
39406 doses
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS 11,8547 L01 ANTINEOPLASTIC AGENTS L01A ALKYLATING AGENTS L01AA Nitrogen mustard analogues L01AA01 Cyclophosphamide(O) 757,5 g L01AA01 Cyclophosphamide(P) 3928 g L01AA02 Chlorambucil(O) 23 g L01AA03 Melphalan(O) 8,4 g L01AA03 Melphalan(P) 30,8 g L01AA06 Ifosfamide(P) 2477 g L01AA07 Trofosfamide(O) 15 g L01AA09 Bendamustine(P) 267,55 g L01AB Alkyl sulfonates L01AB01 Busulfan(O) 5,2 g L01AB01 Busulfan(P) 9,6 g L01AB02 Treosulfan(P) 625 g L01AC Ethylene imines L01AC01 Thiotepa(P) 5,78 g L01AD Nitrosoureas L01AD01 Carmustine(P) 7,7 g
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day L01AD02 Lomustine(O) 28,6 g L01AX Other alkylating agents L01AX03 Temozolomide(O) 753,6 g L01AX04 Dacarbazine(P) 470 g L01B ANTIMETABOLITES L01BA Folic acid analogues L01BA01 Methotrexate(P) 1737,05 g L01BA04 Pemetrexed(P) 233 g L01BB Purine analogues L01BB02 Mercaptopurine(O) 346,75 g L01BB03 Tioguanine(O) 10 g L01BB04 Cladribine(P) 0,26 g L01BB05 Fludarabine(P) 19,5 g L01BB07 Nelarabine(P) 10,5 g L01BC Pyrimidine analogues L01BC01 Cytarabine(P) 2276,5 g L01BC02 Fluorouracil(P) 18445 g L01BC05 Gemcitabine(P) 5022,0536 g L01BC06 Capecitabine(O) 259620 g L01BC07 Azacitidine(P) 184,1 g L01BC83 Trifluridine+Tipiracil(O) 7760 pieces L01C PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS L01CA Vinca alkaloids and analogues L01CA01 Vinblastine(P) 3,18 g L01CA02 Vincristine(P) 2,29 g L01CA04 Vinorelbine(O) 2,3 g L01CA04 Vinorelbine(P) 17,95 g L01CB Podophyllotoxin derivatives L01CB01 Etoposide(O) 235 g L01CB01 Etoposide(P) 509,9 g L01CD Taxanes L01CD01 Paclitaxel(P) 763,3 g L01CD02 Docetaxel(P) 443,52 g L01CD04 Cabazitaxel(P) 1,44 g L01D CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES L01DA Actinomycines L01DA01 Dactinomycin(P) 0,0425 g L01DB Anthracyclines and related substances L01DB01 Doxorubicin(P) 130,1 g L01DB02 Daunorubicin(P) 8,22 g L01DB03 Epirubicin(P) 253,9 g L01DB06 Idarubicin(O) 0,09 g L01DB06 Idarubicin(P) 1,41 g L01DB07 Mitoxantrone(P) 2,46 g L01DB11 Pixantrone(P) 0,783 g L01DC Other cytotoxic antibiotics L01DC01 Bleomycin(P) 5175000 U L01DC03 Mitomycin(P) 6,2 g L01X OTHER ANTINEOPLASTIC AGENTS L01XA Platinum compounds L01XA01 Cisplatin(P) 228,3 g L01XA02 Carboplatin(P) 1941 g L01XA03 Oxaliplatin(P) 884,4 g L01XB Methylhydrazines L01XB01 Procarbazine(O) 152,5 g L01XC Monoclonal antibodies L01XC02 Rituximab(P) 2109,376 g L01XC03 Trastuzumab(P) 1724,55 g L01XC05 Gemtuzumab ozogamicin(P) 0,005 g L01XC06 Cetuximab(P) 132,5 g
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day L01XC07 Bevacizumab(P) 1134,4 g L01XC08 Panitumumab(P) 109,3 g L01XC11 Ipilimumab(P) 0,8 g L01XC12 Brentuximab vedotin(P) 11,5 g L01XC13 Pertuzumab(P) 122,64 g L01XC14 Trastuzumab emtansine(P) 35,74 g L01XC15 Obinutuzumab(P) 90 g L01XC17 Nivolumab(P) 147,18 g L01XC18 Pembrolizumab(P) 261,65 g L01XC19 Blinatumomab(P) 0,0014 g L01XC21 Ramucirumab(P) 2,1 g L01XC24 Daratumumab(P) 379,6 g L01XC26 Inotuzumab ozogamicin(P) 0,004 g L01XC28 Durvalumab(P) 342 g L01XC32 Atezolizumab(P) 31,2 g L01XD Sensitizers used in photodynamic/radiation therapy L01XD04 Aminolevulinic acid(O) 25,5 g L01XE Protein kinase inhibitors L01XE01 Imatinib(O) 14424 g L01XE02 Gefitinib(O) 1305 g L01XE03 Erlotinib(O) 156 g L01XE04 Sunitinib(O) 381,85 g L01XE05 Sorafenib(O) 3494,4 g L01XE06 Dasatinib(O) 660 g L01XE07 Lapatinib(O) 175 g L01XE08 Nilotinib(O) 6630,4 g L01XE09 Temsirolimus(P) 0,39 g L01XE10 Everolimus(O) 34,65 g L01XE11 Pazopanib(O) 15228 g L01XE13 Afatinib(O) 95,48 g L01XE14 Bosutinib(O) 319,2 g L01XE16 Crizotinib(O) 720 g L01XE17 Axitinib(O) 55,776 g L01XE18 Ruxolitinib(O) 249,2 g L01XE21 regorafenib(O) 342,72 g L01XE23 Dabrafenib(O) 3753 g L01XE24 Ponatinib(O) 2,7 g L01XE25 Trametinib(O) 26,37 g L01XE26 Cabozantinib(O) 324,44 g L01XE27 Ibrutinib(O) 5569,2 g L01XE28 Ceritinib(O) 112,5 g L01XE29 Lenvatinib(O) 3,6 g L01XE31 Nintedanib(O) 5775 g L01XE33 Palbociclib(O) 193,725 g L01XE35 Osimertinib(O) 160,8 g L01XE36 Alectinib(O) 67,2 g L01XE39 Midostaurin(O) 21 g L01XE42 Ribociclib(O) 1461,6 g L01XE43 Brigatinib(O) 181,08 g L01XE44 Lorlatinib(O) 6 g L01XX Other antineoplastic agents L01XX01 Amsacrine(P) 0,45 g L01XX02 Asparaginase(P) 1300000 U L01XX05 Hydroxycarbamide(O) 225350 g L01XX11 Estramustine(O) 193,2 g L01XX14 Tretinoin(O) 21 g L01XX17 Topotecan(P) 2,608 g L01XX19 Irinotecan(P) 729 g L01XX23 Mitotane(O) 1650 g L01XX24 Pegaspargase(P) 262500 U
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day L01XX27 Arsenic trioxide(P) 0,8 g L01XX32 Bortezomib(P) 8,9565 g L01XX35 Anagrelide(O) 2 g L01XX41 Eribulin(P) 0,1989 g L01XX42 Panobinostat(O) 0,48 g L01XX45 Carfilzomib(P) 2,76 g L01XX46 Olaparib(O) 5854,4 g L01XX47 Idelalisib(O) 27 g L01XX50 Ixazomib(O) 0,54 g L01XX52 Venetoclax(O) 31,36 g L01XX54 Niraparib(O) 14 g L02 ENDOCRINE THERAPY 4,6931 L02A HORMONES AND RELATED AGENTS 0,6059 L02AB Progestogens 0,0099 L02AB02 Medroxyprogesterone(O) 4785 g 1 g 0,0099 L02AE Gonadotropin releasing hormone analogues 0,5960 L02AE01 Buserelin(N) 1,95 g 1,2 mg 0,0034 L02AE03 Goserelin(P) 8,4276 g 0,129 mg 0,1351 L02AE04 Triptorelin(P) 0,2366 g 0,1 mg 0,0049 L02AE04 Triptorelin(P) 29,3325 g 0,134 mg 0,4526 L02B HORMONE ANTAGONISTS AND RELATED AGENTS 4,0873 L02BA Anti-estrogens 0,7950 L02BA01 Tamoxifen(O) 5953,8 g 0,02 g 0,6155 L02BA03 Fulvestrant(P) 720,5 g 8,3 mg 0,1795 L02BB Anti-androgens 1,4856 L02BB03 Bicalutamide(O) 35558,6 g 0,05 g 1,4705
L02BB04 enzalutamide
(O) 1097,6 g 0,16 g 0,0142
L02BB05 Apalutamide(O) 108 g 0,24 g 0,0009 L02BG Aromatase inhibitors 1,7417 L02BG03 Anastrozole(O) 296,324 g 1 mg 0,6127 L02BG04 Letrozole(O) 1207,95 g 2,5 mg 0,9991 L02BG06 Exemestane(O) 1570,5 g 0,025 g 0,1299 L02BX Other hormone antagonists and related agents 0,0649 L02BX03 Abiraterone(O) 31410 g 1 g 0,0649 L03 IMMUNOSTIMULANTS 0,6755 L03A IMMUNOSTIMULANTS 0,6755 L03AA Colony stimulating factors 0,0747 L03AA02 Filgrastim(P) 8,9256 g 0,35 mg 0,0527 L03AA13 Pegfilgrastim(P) 3,186 g 0,3 mg 0,0220 L03AB Interferons 0,4833 L03AB04 Interferon alfa-2a(P) 35925000000 U 2000000 U 0,0371 L03AB07 Interferon beta-1a(P) 0,6841 g 0,0043 mg 0,3289 L03AB08 Interferon beta-1b(P) 1,2492E+11 U 4000000 U 0,0646 L03AB11 Peginterferon alfa-2a(P) 0,0158 g 0,026 mg 0,0013 L03AB13 Peginterferon beta-1a(P) 0,2211 g 8,9 mcg 0,0514 L03AX Other immunostimulants 0,1175 L03AX03 BCG bacteria(P) 4,3375 g 1,8 mg 0,0050 L03AX13 Glatiramer acetate(P) 1078,24 g 0,02 g 0,1115 L03AX15 Mifamurtide(P) 0,332 g 0,7 mg 0,0010 L03AX16 Plerixafor(P) 0,336 g 16,8 mg <0,0001 L03AX80 Methyluracil(R) 420 g L04 IMMUNOSUPPRESSANTS 6,4862 L04A IMMUNOSUPPRESSANTS 6,4862 L04AA Selective immunosuppressants 1,0819 L04AA03 Antilymphocyte immunoglobulin (horse)(P) 23,75 g L04AA04 Rabbit anti-T-lymphocyte immunoglobulin(P) 15,05 g 0,1 g 0,0003 L04AA06 Mycophenolic acid(O) 274562,4 g 2 g 0,2839 L04AA06 Mycophenolic acid(P) 302 g 2 g 0,0003 L04AA10 Sirolimus(O) 16,65 g 0,003 g 0,0115
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day L04AA13 Leflunomide(O) 5106,6 g 0,02 g 0,5280 L04AA18 Everolimus(O) 0,36 g 1,5 mg 0,0005 L04AA23 Natalizumab(P) 48,9 g 0,01 g 0,0101 L04AA24 Abatacept(P) 162,5 g 0,027 g 0,0124 L04AA25 Eculizumab(P) 37,8 g 0,064 g 0,0012 L04AA27 Fingolimod(O) 5,124 g 0,5 mg 0,0212
L04AA29 Tofacitinib
(O) 52,92 g 10 mg 0,0109
L04AA31 Teriflunomide(O) 670,712 g 14 mg 0,0991 L04AA32 Apremilast(O) 0,69 g 60 mg <0,0001 L04AA33 Vedolizumab(P) 91,5 g 5,4 mg 0,0350 L04AA34 Alemtuzumab(P) 0,78 g 0,13 mg 0,0124 L04AA36 Ocrelizumab(P) 82,5 g 3,29 mg 0,0519 L04AA40 Cladribine(O) 0,52 g 0,34 mg 0,0032 L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors 1,1249 L04AB01 Etanercept(P) 700,4 g 0,007 g 0,2069 L04AB02 Infliximab(P) 978,1 g 3,75 mg 0,5393 L04AB04 Adalimumab(P) 403,64 g 2,9 mg 0,2878 L04AB05 Certolizumab pegol(P) 31,2 g 14 mg 0,0046 L04AB06 Golimumab(P) 69,3 g 1,66 mg 0,0863 L04AC Interleukin inhibitors 0,3520 L04AC02 Basiliximab(P) 0,76 g 0,04 g <0,0001 L04AC03 Anakinra(P) 100,6005 g 0,1 g 0,0021 L04AC05 Ustekinumab(P) 47,275 g 0,54 mg 0,1810 L04AC07 Tocilizumab(P) 725,88 g 0,02 g 0,0750 L04AC10 Secukinumab(P) 379,5 g 10 mg 0,0785 L04AC13 Ixekizumab(P) 3,68 g 2,9 mg 0,0026 L04AC14 Sarilumab(P) 53,3 g 14,3 mg 0,0077 L04AC16 Guselkumab(P) 4,3 g 1,79 mg 0,0050 L04AC18 Risankizumab(P) 0,45 g L04AD Calcineurin inhibitors 0,4759 L04AD01 Ciclosporin(O) 28028,75 g 0,25 g 0,2318 L04AD01 Ciclosporin(P) 55 g 0,25 g 0,0005 L04AD02 Tacrolimus(O) 588,8525 g 5 mg 0,2435 L04AD02 Tacrolimus(P) 0,2 g 5 mg 0,0001 L04AX Other immunosuppressants 3,4515 L04AX01 Azathioprine(O) 27750 g 0,15 g 0,3825 L04AX02 Thalidomide(O) 697,2 g 0,1 g 0,0144 L04AX03 Methotrexate(O) 3360 g 2,5 mg 2,7790 L04AX03 Methotrexate(P) 34,43 g 2,5 mg 0,0285 L04AX04 Lenalidomide(O) 350,91 g 0,01 g 0,0726 L04AX05 Pirfenidone(O) 22540,14 g 2,4 g 0,0194
L04AX06 Pomalidomide
(O) 10,416 g 3 mg 0,0072
L04AX07 Dimethyl fumarate(O) 34345,92 g 0,48 g 0,1480 M MUSCULO-SKELETAL SYSTEM 84,1176 M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS 68,8640
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON- STEROIDS
68,8533
M01AB Acetic acid derivatives and related substances 8,9049 M01AB01 Indometacin(O) 3876,5 g 0,1 g 0,0802 M01AB05 Diclofenac(O) 343897,375 g 0,1 g 7,1108 M01AB05 Diclofenac(P) 9036,75 g 0,1 g 0,1869 M01AB05 Diclofenac(R) 14496,5 g 0,1 g 0,2997 M01AB16 Aceclofenac(O) 40644 g 0,2 g 0,4202 M01AB82 Diclofenac+Omeprazole(O) 39035,25 g 0,1 g 0,8071 M01AC Oxicams 4,0574 M01AC01 Piroxicam(O) 1453,2 g 0,02 g 0,1502 M01AC05 Lornoxicam(O) 1963,84 g 0,012 g 0,3384 M01AC05 Lornoxicam(P) 12,96 g 0,012 g 0,0022
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day M01AC06 Meloxicam(O) 25638,6 g 0,015 g 3,5342 M01AC06 Meloxicam(P) 234,7 g 0,015 g 0,0324 M01AE Propionic acid derivatives 39,3010 M01AE01 Ibuprofen(O) 15104167,6 g 1,2 g 26,0260 M01AE01 Ibuprofen(P) 4052 g 1,2 g 0,0070 M01AE02 Naproxen(O) 546426,1 g 0,5 g 2,2597 M01AE03 Ketoprofen(O) 128869,875 g 0,15 g 1,7764 M01AE03 Ketoprofen(P) 13796 g 0,15 g 0,1902 M01AE17 Dexketoprofen(O) 69992,5 g 0,075 g 1,9297 M01AE17 Dexketoprofen(P) 4123 g 0,075 g 0,1137 M01AE52 Naproxen+Esomeprazole(O) 1689585 g 0,5 g 6,9872 M01AE82 Ibuprofen+Phenylephrine(O) 6542,4 g 1,2 g 0,0113 M01AG Fenamates 0,0035 M01AG02 Tolfenamic acid(O) 508 g 0,3 g 0,0035 M01AH Coxibs 8,3387 M01AH01 Celecoxib(O) 61777 g 0,2 g 0,6387 M01AH05 Etoricoxib(O) 223434,12 g 60 mg 7,7000
M01AX Other antiinflammatory and antirheumatic agents, non-steroids 8,2477
M01AX01 Nabumetone(O) 144040 g 1 g 0,2978 M01AX05 Glucosamine(O) 5767132,71 g 1,5 g 7,9499 M01C SPECIFIC ANTIRHEUMATIC AGENTS 0,0108 M01CC Penicillamine and similar agents 0,0108 M01CC01 Penicillamine(O) 2600 g 0,5 g 0,0108 M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN M02AA Antiinflammatory preparations, non-steroids for topical use M02AA10 Ketoprofen(C) 1189550 g M02AA12 Naproxen(C) 920975 g M02AA13 Ibuprofen(C) 902350 g M02AA15 Diclofenac(C) 385499 pieces M02AA15 Diclofenac(C) 35872477,25 g M02AA81 Ibuprofen+Levomenthol(C) 1766400 g M02AC Preparations with salicylic acid derivatives
M02AC80 Methyl salicylate+Levomenthol+Eucalyptus oil+Turpentine oil(C) 79663 g
M02AX Other topical products for joint and muscular pain M02AX80 Nicoboxil+Nonivamide(C) 183540 g M02AX86 Camphor+Methyl salicylate+Levomenthol(C) 12900 g
M02AX90 Camphor+Salicylic acid+Turpentine oil+Venenum Viperae berus(C) 1063050 g
M02AX92 Benzyl nicotinate+Nonivamide+Camphor+Turpentine oil+Dimethyl sulfoxide(C)
963080 g
M03 MUSCLE RELAXANTS 0,9908 M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS M03AB Choline derivatives M03AB01 Suxamethonium chloride(P) 3615,5 g M03AC Other quaternary ammonium compounds M03AC04 Atracurium besilate(P) 1391,5 g M03AC06 Pipecuronium bromide(P) 31,2 g M03AC09 Rocuronium bromide(P) 976 g M03AX Other muscle relaxants, peripherally acting agents M03AX01 Botulinum toxin(P) 1345200 U M03B MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS 0,9908 M03BX Other centrally acting agents 0,9908 M03BX01 Baclofen(O) 4624,25 g 0,05 g 0,1912 M03BX01 Baclofen(P) 2,8218 g 0,55 mg 0,0106 M03BX02 Tizanidine(O) 4573,68 g 0,012 g 0,7881 M03BX04 Tolperisone(O) 81 g 0,2 g 0,0008 M03C MUSCLE RELAXANTS, DIRECTLY ACTING AGENTS
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day M03CA Dantrolene and derivatives M03CA01 Dantrolene(P) 15,12 g M04 ANTIGOUT PREPARATIONS 9,4479 M04A ANTIGOUT PREPARATIONS 9,4479 M04AA Preparations inhibiting uric acid production 9,4323 M04AA01 Allopurinol(O) 1286950 g 0,4 g 6,6526 M04AA03 Febuxostat(O) 107546,88 g 0,08 g 2,7797 M04AB Preparations increasing uric acid excretion 0,0055 M04AB03 Benzbromarone(O) 268 g 0,1 g 0,0055 M04AC Preparations with no effect on uric acid metabolism 0,0100 M04AC01 Colchicine(O) 4,855 g 1 mg 0,0100 M05 DRUGS FOR TREATMENT OF BONE DISEASES 4,8148
M05B DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION 4,8148
M05BA Bisphosphonates 0,9000 M05BA03 Pamidronic acid(P) 22,62 g 0,06 g 0,0008 M05BA04 Alendronic acid(O) 742 g 0,01 g 0,1534 M05BA06 Ibandronic acid(O) 1344,15 g 0,005 g 0,5559 M05BA06 Ibandronic acid(P) 1,83 g 0,006 g 0,0006 M05BA07 Risedronic acid(O) 436,1 g 0,005 g 0,1803 M05BA08 Zoledronic acid(P) 17,232 g 0,004 g 0,0089 M05BB Bisphosphonates, combinations 2,7503 M05BB03 Alendronic acid+Colecalciferol(O) 13301,12 g 10 mg 2,7503 M05BX Other drugs affecting bone structure and mineralization 1,1646 M05BX04 Denosumab(P) 185,864 g 0,33 mg 1,1646 M05BX05 Burosumab(P) 0,53 g N NERVOUS SYSTEM 134,1934 N01 ANESTHETICS N01A ANESTHETICS, GENERAL N01AB Halogenated hydrocarbons N01AB06 Isoflurane(I) 14400 ml N01AB07 Desflurane(I) 73440 ml N01AB08 Sevoflurane(I) 778750 ml N01AF Barbiturates, plain N01AF03 Thiopental(P) 2130 g N01AH Opioid anesthetics N01AH01 Fentanyl(I) 30,872 g N01AH01 Fentanyl(P) 2,003 g N01AH06 Remifentanil(P) 15,115 g N01AX Other general anesthetics N01AX03 Ketamine(P) 419 g N01AX07 Etomidate(P) 74,2 g N01AX10 Propofol(P) 64708,5 g N01AX11 Sodium oxybate(P) 1660 g N01AX13 Nitrous oxide(I) 11116000 ml N01AX14 Esketamine(P) 374,5 g N01B ANESTHETICS, LOCAL N01BA Esters of aminobenzoic acid N01BA02 Procaine(P) 1,25 g N01BB Amides N01BB01 Bupivacaine(Infilt, P) 3084,45 g N01BB01 Bupivacaine(P) 285,4 g N01BB02 Lidocaine(C) 1300 ml N01BB02 Lidocaine(C) 2215,5 g N01BB02 Lidocaine(NA) 85200 ml N01BB02 Lidocaine(O) 65100 g N01BB02 Lidocaine(P) 25379,1 g N01BB03 Mepivacaine(dental) 1565,7 g N01BB08 Articaine(P) 2,4 g N01BB09 Ropivacaine(P) 733,9 g
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day N01BB80 Articaine+Epinephrine(dental) 1236070 ml N01BB80 Articaine+Epinephrine(O) 230310 ml N01BB81 Bupivacaine+Epinephrine(P) 250400 ml N01BB82 Lidocaine+Epinephrine(dental) 180 ml N01BB82 Lidocaine+Epinephrine(P) 62400 ml N01BB83 Lidocaine+Prilocaine(C) 53650 g N01BB86 Lidocaine+Chlorhexidine(urethral) 1096175 g N01BB87 Mepivacaine+Epinephrine(P) 90 ml N01BC Esters of benzoic acid N01BC01 Cocaine(NA) 285 g N01BX Other local anesthetics N01BX04 Capsaicin(C) 77,486 g N02 ANALGESICS 23,5231 N02A OPIOIDS 7,7385 N02AA Natural opium alkaloids 0,7684 N02AA01 Morphine(O) 6033 g 0,1 g 0,1247 N02AA01 Morphine(P) 700,8 g 0,03 g 0,0483 N02AA05 Oxycodone(O) 17711,05 g 0,075 g 0,4883 N02AA05 Oxycodone(P) 27,65 g 0,03 g 0,0019 N02AA08 Dihydrocodeine(O) 7401 g 0,15 g 0,1020 N02AA55 Oxycodone+Naloxone(O) 115,2 g 75 mg 0,0032 N02AB Phenylpiperidine derivatives 0,1536 N02AB02 Pethidine(P) 22 g 0,4 g 0,0001 N02AB02 Pethidine(P, V) 3034 g 0,4 g 0,0157 N02AB03 Fentanyl(O) 2,9792 g N02AB03 Fentanyl(SL) 2,986 g 0,6 mg 0,0103 N02AB03 Fentanyl(TD) 74,0196 g 1,2 mg 0,1275 N02AE Oripavine derivatives 0,0101 N02AE01 Buprenorphine(TD) 5,8666 g 1,2 mg 0,0101 N02AJ Opioids in combination with non-opioid analgesics 4,9355 N02AJ06 Codeine+Paracetamol(O) 5858890 pieces 3 pieces 4,0382 N02AJ13 Tramadol+Paracetamol(O) 1880,25 g 150 mg 0,0259 N02AJ14 Tramadol+Dexketoprofen(O) 63216 g 150 mg 0,8714 N02AX Other opioids 1,8708 N02AX02 Tramadol(O) 266855 g 0,3 g 1,8393 N02AX02 Tramadol(P) 4571 g 0,3 g 0,0315 N02AX02 Tramadol(R) 1 g 0,3 g <0,0001 N02B OTHER ANALGESICS AND ANTIPYRETICS 14,8474 N02BA Salicylic acid and derivatives 0,9048 N02BA01 Acetylsalicylic acid (O) 1109871,96 g 3 g 0,7650 N02BA80 Acetylsalicylic acid +Ascorbic acid(O) 202830 g 3 g 0,1398 N02BB Pyrazolones 0,0021 N02BB02 Metamizole sodium(O) 235 g 3 g 0,0002 N02BB02 Metamizole sodium(P, V) 2810 g 3 g 0,0019 N02BE Anilides 13,9405 N02BE01 Paracetamol(O) 13820637,2 g 3 g 9,5257 N02BE01 Paracetamol(P) 291250 g 3 g 0,2007 N02BE01 Paracetamol(R) 67488,55 g 3 g 0,0465 N02BE52 Paracetamol+Pseudoephedrine+Diphenhydramine(O) 58784 g 3 g 0,0405 N02BE75 Paracetamol+Guaifenesin+Phenylephrine(O) 255404,5 g 3 g 0,1760
N02BE81 Paracetamol+Chlorphenamine+Pseudoephedrine+Dextromethorphan( O)
429356 g 3 g 0,2959
N02BE83 Paracetamol+Caffeine(O) 194850 g 3 g 0,1343 N02BE84 Paracetamol+Phenylephrine+Ascorbic acid(O) 1296233,75 g 3 g 0,8934 N02BE85 Paracetamol+Pheniramine+Ascorbic acid(O) 106990,4 g 3 g 0,0737
N02BE86 Paracetamol+Phenylephrine+Terpin hydrate+Ascorbic acid+Caffeine(O)
408894 g 3 g 0,2818
N02BE87 Paracetamol+Pseudoephedrine(O) 66250 g 3 g 0,0457 N02BE91 Paracetamol+Ascorbic acid(O) 3696 g 3 g 0,0025 N02BE92 Paracetamol+Codeine(O) 918760 g 3 g 0,6332
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day N02BE94 Paracetamol+Codeine+Caffeine(O) 1760004 g 3 g 1,2131 N02BE95 Paracetamol+Phenylephrine(O) 73835 g 3 g 0,0509 N02BE97 Paracetamol+Pseudoephedrine+Dextromethorphan(O) 473518 g 3 g 0,3264 N02C ANTIMIGRAINE PREPARATIONS 0,9372 N02CC Selective serotonin (5HT1) agonists 0,9278 N02CC01 Sumatriptan(N) 1,96 g 0,02 g 0,0002 N02CC01 Sumatriptan(O) 19058,4 g 0,05 g 0,7881 N02CC03 Zolmitriptan(O) 49,09 g 2,5 mg 0,0406 N02CC04 Rizatriptan(O) 69,75 g 0,01 g 0,0144 N02CC07 Frovatriptan(O) 102,125 g 2,5 mg 0,0845 N02CD Calcitonin gene-related peptide (CGRP) antagonists 0,0094 N02CD01 Erenumab(P) 11,34 g 2,5 mg 0,0094 N03 ANTIEPILEPTICS 10,9169 N03A ANTIEPILEPTICS 10,9169 N03AA Barbiturates and derivatives 0,4606 N03AA02 Phenobarbital(O) 19655 g 0,1 g 0,4064 N03AA02 Phenobarbital(P) 70 g 0,1 g 0,0014 N03AA03 Primidone(O) 31900 g 1,25 g 0,0528 N03AB Hydantoin derivatives 0,0414 N03AB02 Phenytoin(O) 5810 g 0,3 g 0,0400 N03AB02 Phenytoin(P) 197,5 g 0,3 g 0,0014 N03AD Succinimide derivatives 0,0138 N03AD01 Ethosuximide(O) 8350 g 1,25 g 0,0138 N03AE Benzodiazepine derivatives 0,5706 N03AE01 Clonazepam(O) 2207,76 g 0,008 g 0,5706 N03AE01 Clonazepam(P) 0,005 g 0,008 g <0,0001 N03AF Carboxamide derivatives 2,8644 N03AF01 Carbamazepine(O) 991171 g 1 g 2,0495 N03AF02 Oxcarbazepine(O) 393825 g 1 g 0,8143 N03AF03 Rufinamide(O) 400 g 1,4 g 0,0006 N03AG Fatty acid derivatives 1,6063 N03AG01 Valproic acid(O) 1153930 g 1,5 g 1,5907 N03AG01 Valproic acid(P) 1043,1 g 1,5 g 0,0014 N03AG04 Vigabatrin(O) 13750 g 2 g 0,0142 N03AX Other antiepileptics 5,3597 N03AX03 Sultiame(O) 3990 g 0,4 g 0,0206 N03AX09 Lamotrigine(O) 98749,28 g 0,3 g 0,6806 N03AX11 Topiramate(O) 34845 g 0,3 g 0,2402 N03AX12 Gabapentin(O) 1308465 g 1,8 g 1,5031 N03AX14 Levetiracetam(O) 440850 g 1,5 g 0,6077 N03AX14 Levetiracetam(P) 260 g 1,5 g 0,0004 N03AX16 Pregabalin(O) 334306,35 g 0,3 g 2,3042 N03AX17 Stiripentol(O) 1245 g 1 g 0,0026 N03AX18 Lacosamide(O) 7,7 g 0,3 g 0,0001 N03AX22 perampanel(O) 1,344 g 8 mg 0,0003 N04 ANTI-PARKINSON DRUGS 3,7744 N04A ANTICHOLINERGIC AGENTS 0,6093 N04AA Tertiary amines 0,6093 N04AA01 Trihexyphenidyl(O) 2946,6 g 0,01 g 0,6093 N04B DOPAMINERGIC AGENTS 3,1652 N04BA Dopa and dopa derivatives 1,4237 N04BA03 Levodopa +Carbidopa+Entacapone(O) 71752,5 g 0,45 g 0,3297 N04BA80 Levodopa +Benserazide(O) 310370 g 0,6 g 1,0696 N04BA81 Levodopa +Carbidopa(intestin) 18676 g N04BA81 Levodopa +Carbidopa(O) 7085,9 g 0,6 g 0,0244 N04BB Adamantane derivatives 0,3031 N04BB01 Amantadine(O) 29320 g 0,2 g 0,3031 N04BB01 Amantadine(P) 36 g N04BC Dopamine agonists 0,7715 N04BC04 Ropinirole(O) 1045,667 g 0,006 g 0,3604
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day N04BC05 Pramipexole(O) 466,1869 g 2,5 mg 0,3856 N04BC07 Apomorphine(P) 246,9 g 20 mg 0,0255 N04BD Monoamine oxidase type B inhibitors 0,6669 N04BD02 Rasagiline(O) 322,51 g 0,001 g 0,6669 N05 PSYCHOLEPTICS 43,6288 N05A ANTIPSYCHOTICS 9,5838 N05AA Phenothiazines with aliphatic side-chain 0,1621 N05AA01 Chlorpromazine(O) 12357 g 0,3 g 0,0852 N05AA01 Chlorpromazine(P) 54 g 0,1 g 0,0011 N05AA02 Levomepromazine(O) 10969 g 0,3 g 0,0756 N05AA02 Levomepromazine(P, V) 12,5 g 0,1 g 0,0003 N05AB Phenothiazines with piperazine structure 0,0698 N05AB02 Fluphenazine(P) 3,5 g 0,001 g 0,0072 N05AB03 Perphenazine(O) 423,2 g 0,03 g 0,0292 N05AB03 Perphenazine(P) 161,218 g 0,01 g 0,0333 N05AB04 Prochlorperazine(O) 2,94 g 0,1 g 0,0001 N05AC Phenothiazines with piperidine structure 0,0012 N05AC01 Periciazine(O) 28,8 g 0,05 g 0,0012 N05AC02 Thioridazine(O) 2,5 g 0,3 g <0,0001 N05AD Butyrophenone derivatives 1,0330 N05AD01 Haloperidol(O) 2091,99 g 0,008 g 0,5407 N05AD01 Haloperidol(P) 805,525 g 0,008 g 0,2082 N05AD03 Melperone(O) 38880 g 0,3 g 0,2680 N05AD08 Droperidol(P) 19,45 g 2,5 mg 0,0161 N05AE Indole derivatives 0,0995 N05AE03 Sertindole(O) 739,424 g 0,016 g 0,0956 N05AE04 Ziprasidone(O) 149,28 g 0,08 g 0,0039 N05AE05 Lurasidone(O) 2,604 g 60 mg 0,0001 N05AF Thioxanthene derivatives 0,8720 N05AF01 Flupentixol(O) 364,4 g 0,006 g 0,1256 N05AF01 Flupentixol(P) 109 g 0,004 g 0,0563 N05AF03 Chlorprothixene(O) 29695 g 0,3 g 0,2047 N05AF05 Zuclopenthixol(O) 1368 g 0,03 g 0,0943 N05AF05 Zuclopenthixol(P) 47,5 g 0,03 g 0,0033 N05AF05 Zuclopenthixol(P) 2813,6 g 0,015 g 0,3878 N05AG Diphenylbutylpiperidine derivatives 0,0001 N05AG02 Pimozide(O) 0,225 g 0,004 g 0,0001 N05AH Diazepines, oxazepines and thiazepines 5,4396 N05AH02 Clozapine(O) 91236,75 g 0,3 g 0,6288 N05AH03 Olanzapine(O) 10312,68 g 0,01 g 2,1324 N05AH03 Olanzapine(P) 154,4 g 0,01 g 0,0319 N05AH04 Quetiapine(O) 511891 g 0,4 g 2,6461 N05AH05 Asenapine(SL) 3 g 20 mg 0,0003 N05AL Benzamides 0,1453 N05AL01 Sulpiride(O) 21868,5 g 0,8 g 0,0565 N05AL05 Amisulpride(O) 17172 g 0,4 g 0,0888 N05AN Lithium 0,2623 N05AN01 Lithium(O) 114180 g 0,9 g 0,2623 N05AX Other antipsychotics 1,4989 N05AX08 Risperidone(O) 1623,2 g 0,005 g 0,6713 N05AX08 Risperidone(P) 22,275 g 2,7 mg 0,0171 N05AX12 Aripiprazole(O) 4895,16 g 0,015 g 0,6748 N05AX12 Aripiprazole(P) 8,8725 g 0,015 g 0,0012 N05AX12 Aripiprazole(P) 394,4 g 0,0133 g 0,0613 N05AX13 Paliperidone(P) 87,9 g 2,5 mg 0,0727 N05AX15 Cariprazine(O) 0,756 g 3 mg 0,0005 N05B ANXIOLYTICS 13,0269 N05BA Benzodiazepine derivatives 13,0262 N05BA01 Diazepam(O) 26947,05 g 0,01 g 5,5719 N05BA01 Diazepam(P) 490,7 g 0,01 g 0,1015
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day N05BA01 Diazepam(R) 60,15 g 0,01 g 0,0124 N05BA02 Chlordiazepoxide(O) 0,5 g 0,03 g <0,0001 N05BA04 Oxazepam(O) 6,5 g 0,05 g 0,0003 N05BA06 Lorazepam(O) 735,555 g 2,5 mg 0,6084 N05BA06 Lorazepam(P) 10,76 g 2,5 mg 0,0089 N05BA08 Bromazepam(O) 5716,95 g 0,01 g 1,1821 N05BA09 Clobazam(O) 333 g 0,02 g 0,0344 N05BA12 Alprazolam(O) 2655,47 g 0,001 g 5,4908 N05BA80 Phenazepam(O) 7,525 g 0,001 g 0,0156 N05BB Diphenylmethane derivatives 0,0002 N05BB01 Hydroxyzine(O) 6,3 g 0,075 g 0,0002 N05BE Azaspirodecanedione derivatives 0,0005 N05BE01 Buspirone(O) 7,2 g 0,03 g 0,0005 N05C HYPNOTICS AND SEDATIVES 21,0181 N05CD Benzodiazepine derivatives 0,3026 N05CD02 Nitrazepam(O) 272,85 g 0,005 g 0,1128 N05CD05 Triazolam(O) 0,03 g 0,25 mg 0,0002 N05CD08 Midazolam(O) 0,24 g N05CD08 Midazolam(O) 974,8997 g 0,015 g 0,1344 N05CD08 Midazolam(P) 400,2199 g 0,015 g 0,0552 N05CF Benzodiazepine related drugs 20,3792 N05CF01 Zopiclone(O) 58842,525 g 7,5 mg 16,2226 N05CF02 Zolpidem(O) 20102 g 0,01 g 4,1565 N05CM Other hypnotics and sedatives 0,3363 N05CM09 Valerianae radix(O) 468750 pieces 3 pieces 0,3231 N05CM18 Dexmedetomidine(P) 6,3842 g 1 mg 0,0132 N06 PSYCHOANALEPTICS 39,8858 N06A ANTIDEPRESSANTS 34,7835 N06AA Non-selective monoamine reuptake inhibitors 1,9432 N06AA04 Clomipramine(O) 4674,15 g 0,1 g 0,0966 N06AA04 Clomipramine(P) 2,5 g 0,1 g 0,0001 N06AA09 Amitriptyline(O) 53941,75 g 0,075 g 1,4872 N06AA10 Nortriptyline(O) 13032,5 g 0,075 g 0,3593 N06AB Selective serotonin reuptake inhibitors 20,5822 N06AB03 Fluoxetine(O) 32820,04 g 0,02 g 3,3931 N06AB04 Citalopram(O) 13807,26 g 0,02 g 1,4275 N06AB05 Paroxetine(O) 22974,6 g 0,02 g 2,3752 N06AB06 Sertraline(O) 130599,3 g 0,05 g 5,4008 N06AB08 Fluvoxamine(O) 305,5 g 0,1 g 0,0063 N06AB10 Escitalopram(O) 38589,16 g 0,01 g 7,9791 N06AF Monoamine oxidase inhibitors, non-selective 0,0050 N06AF04 Tranylcypromine(O) 24 g 0,01 g 0,0050 N06AG Monoamine oxidase type A inhibitors 0,0001 N06AG02 Moclobemide(O) 15 g 0,3 g 0,0001 N06AX Other antidepressants 12,2531 N06AX03 Mianserin(O) 24,3 g 0,06 g 0,0008 N06AX05 Trazodone(O) 6357 g 0,3 g 0,0438 N06AX11 Mirtazapine(O) 33217,02 g 0,03 g 2,2894 N06AX12 Bupropione(O) 107356,5 g 0,3 g 0,7399 N06AX14 Tianeptine(O) 25214,625 g 0,0375 g 1,3903 N06AX16 Venlafaxine(O) 167874,6 g 0,1 g 3,4712 N06AX18 Reboxetine(O) 1,44 g 0,008 g 0,0004 N06AX21 Duloxetine(O) 67255,62 g 0,06 g 2,3178 N06AX22 Agomelatine(O) 17253,6 g 0,025 g 1,4270 N06AX26 Vortioxetine(O) 2768,36 g 10 mg 0,5724
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
1,3297
N06BA Centrally acting sympathomimetics 1,0734 N06BA04 Methylphenidate(O) 14412,18 g 0,03 g 0,9933 N06BA07 Modafinil(O) 1064 g 0,3 g 0,0073
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day N06BA09 Atomoxetine(O) 2814,504 g 0,08 g 0,0727 N06BA12 Lisdexamfetamine dimesylate(O) 8,1 g N06BC Xanthine derivatives N06BC81 Caffeine citrate(O, P) 51,2 g N06BX Other psychostimulants and nootropics 0,2563 N06BX03 Piracetam (O) 281304 g 2,4 g 0,2424 N06BX13 Idebenone(O) 918 g 0,9 g 0,0021 N06BX18 Vinpocetine(O) 85,5 g 15 mg 0,0118 N06BX83 Aminobutyric acid(O) 25320 g N06D ANTI-DEMENTIA DRUGS 3,7727 N06DA Anticholinesterases 0,9913 N06DA02 Donepezil(O) 3595,48 g 7,5 mg 0,9913 N06DX Other anti-dementia drugs 2,7814 N06DX01 Memantine(O) 4312,64 g 0,02 g 0,4459 N06DX02 Ginkgo folium(O) 135543,6 g 0,12 g 2,3355 N06DX80 cerebrolysine(P) 4,304 g N07 OTHER NERVOUS SYSTEM DRUGS 12,4644 N07A PARASYMPATHOMIMETICS 0,3831 N07AA Anticholinesterases 0,3831 N07AA01 neostigmine(P) 31,43 g 0,002 g 0,0325 N07AA02 Pyridostigmine bromide(O) 28146 g 0,18 g 0,3233 N07AA03 Distigmine bromide(O) 0,5 g 0,005 g 0,0002 N07AA80 Neostigmine+Glycopyrronium(P) 13110 ml 1 ml 0,0271 N07B DRUGS USED IN ADDICTIVE DISORDERS 3,5444 N07BA Drugs used in nicotine dependence 1,9211 N07BA01 Nicotine(O) 17724,55 g 0,03 g 1,2216 N07BA01 Nicotine(TD) 4436,775 g 0,014 g 0,6553 N07BA03 Varenicline(O) 42,751 g 2 mg 0,0442 N07BB Drugs used in alcohol dependence 0,4070 N07BB01 Disulfiram(O) 33255 g 0,2 g 0,3438 N07BB01 Disulfiram(P) 51 g N07BB03 Acamprosate(O) 55,944 g 2 g 0,0001 N07BB04 Naltrexone(O) 1207,4 g 50 mg 0,0499 N07BB05 nalmefene(O) 115,164 g 18 mg 0,0132 N07BC Drugs used in opioid dependence 1,2163 N07BC02 Methadone(O) 14155 g 0,025 g 1,1707 N07BC51 Buprenorphine+Naloxone(SL) 176,148 g 8 mg 0,0455 N07C ANTIVERTIGO PREPARATIONS 8,5003 N07CA Antivertigo preparations 8,5003 N07CA01 Betahistine(O) 84375,6 g 0,024 g 7,2694 N07CA02 Cinnarizine(O) 51543,75 g 0,09 g 1,1842 N07CA03 Flunarizine(O) 3,15 g 0,01 g 0,0007 N07CA80 Cinnarizine+Dimenhydrinate(O) 2005 g 90 mg 0,0461 N07X OTHER NERVOUS SYSTEM DRUGS 0,0366 N07XX Other nervous system drugs 0,0366 N07XX02 Riluzole(O) 1481,2 g 0,1 g 0,0306 N07XX06 Tetrabenazine(O) 249,2 g 0,1 g 0,0052 N07XX07 Fampridine(O) 7,84 g 20 mg 0,0008 N07XX14 Edaravone(P) 2,7 g
P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS 0,9680
P01 ANTIPROTOZOALS 0,7483
P01A AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES
P01AB Nitroimidazole derivatives P01AB01 Metronidazole (O, V) 1962 g P01B ANTIMALARIALS 0,7483 P01BA Aminoquinolines 0,7036 P01BA02 Hydroxychloroquine(O) 175440 g 0,516 g 0,7030 P01BA03 Primaquine(O) 4,5 g 0,015 g 0,0006
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day P01BB Biguanides 0,0440 P01BB51 Proguanil+Atovaquone(O) 1740 pieces 16 pieces 0,0002 P01BB51 Proguanil+Atovaquone(O) 84612 pieces 4 pieces 0,0437 P01BC Methanolquinolines <0,0001 P01BC02 Mefloquine(O) 6 g 1 g <0,0001 P01BD Diaminopyrimidines 0,0006 P01BD01 Pyrimethamine(O) 23,25 g 0,075 g 0,0006 P01C AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS <0,0001 P01CX Other agents against leishmaniasis and trypanosomiasis <0,0001 P01CX01 Pentamidine isethionate(P) 1,5 g 0,28 g <0,0001 P02 ANTHELMINTICS 0,2197 P02B ANTITREMATODALS 0,0003 P02BA Quinoline derivatives and related substances 0,0003 P02BA01 Praziquantel(O) 385,2 g 3 g 0,0003 P02C ANTINEMATODAL AGENTS 0,2194 P02CA Benzimidazole derivatives 0,2191 P02CA01 Mebendazole(O) 19592 g 0,2 g 0,2026 P02CA03 Albendazole(O) 3200 g 0,4 g 0,0165 P02CF Avermectines 0,0003 P02CF01 Ivermectin(O) 1,956 g 12 mg 0,0003
P03 ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
P03A ECTOPARASITICIDES, INCL. SCABICIDES P03AC Pyrethrines, incl. synthetic compounds P03AC04 Permethrin(C) 58600 g P03AX Other ectoparasiticides, incl. scabicides P03AX01 Benzyl benzoate(C) 344730 g R RESPIRATORY SYSTEM 93,8787 R01 NASAL PREPARATIONS 38,4271
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
35,6572
R01AA Sympathomimetics, plain 22,8751 R01AA05 Oxymetazoline(N) 315,3 g 0,4 mg 1,6299 R01AA07 Xylometazoline(N) 8219,765 g 0,8 mg 21,2452 R01AB Sympathomimetics, combinations excl. corticosteroids 3,0493 R01AB83 Xylometazoline+Ipratropium bromide(N) 238100 ml 0,8 ml 0,6154 R01AB85 Xylometazoline+Dexpanthenol(N) 941680 ml 0,8 ml 2,4339 R01AC Antiallergic agents, excl. corticosteroids 0,3321 R01AC03 Azelastine(N) 89,93 g 0,56 mg 0,3321 R01AD Corticosteroids 9,4007 R01AD01 Beclometasone(N) 7,57 g 0,4 mg 0,0391 R01AD05 Budesonide(N) 41,513 g 0,2 mg 0,4292 R01AD08 Fluticasone(N) 92,313 g 0,2 mg 0,9544 R01AD09 Mometasone(N) 402,346 g 0,2 mg 4,1597 R01AD12 Fluticasone furoate(N) 179,8368 g 0,11 mg 3,3805 R01AD81 Fluticasone+Azelastine(N) 847080 doses 4 doses 0,4379 R01AX Other nasal preparations R01AX06 Mupirocin(N) 21 g R01AX83 Retinol+Tocopherol(N) 156860 ml R01B NASAL DECONGESTANTS FOR SYSTEMIC USE 2,7699 R01BA Sympathomimetics 2,7699 R01BA02 Pseudoephedrine(O) 179500,68 g 0,24 g 1,5465 R01BA81 Pseudoephedrine+Triprolidine(O) 33867,12 g 0,24 g 0,2918 R01BA84 Pseudoephedrine+Guaifenesin(O) 10288,8 g 0,24 g 0,0886 R01BA89 Pseudoephedrine+Loratadine(O) 18224,64 g 0,24 g 0,1570 R01BA93 Pseudoephedrine+Cetirizine(O) 79625,28 g 0,24 g 0,6860 R02 THROAT PREPARATIONS 2,8356 R02A THROAT PREPARATIONS 2,8356 R02AA Antiseptics 2,3211 R02AA06 Cetylpyridinium chloride(O) 122526 pieces
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day R02AA82 Benzydamine+Cetylpyridinium chloride(O) 1197750 ml R02AA82 Benzydamine+Cetylpyridinium chloride(O) 1908656 pieces 6 pieces 0,6578 R02AA89 Povidone, iodinated+Allantoin(O) 357870 ml R02AA92 Dequalinium+Cinchocaine(O) 1039020 pieces 6 pieces 0,3581 R02AA94 Amylmetacresol+Dichlorobenzyl alcohol(O) 1028304 pieces 6 pieces 0,3544 R02AA95 Amylmetacresol+Dichlorobenzyl alcohol+Levomenthol(O) 1749528 pieces 6 pieces 0,6029 R02AA96 Amylmetacresol+Dichlorobenzyl alcohol+Ascorbic acid(O) 634872 pieces 6 pieces 0,2188 R02AA98 Cetylpyridinium chloride+Benzocaine(O) 374886 pieces 6 pieces 0,1292 R02AD Anesthetics, local 0,1534 R02AD80 Lidocaine+Propyl parahydroxybenzoate(O) 445060 pieces 6 pieces 0,1534 R02AX Other throat preparations 0,3611 R02AX01 Flurbiprofen(O) 7683,97 g 44 mg 0,3611 R02AX80 Thyme herb+Sage leaf(O) 32475 ml R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES 27,2911 R03A ADRENERGICS, INHALANTS 19,3775 R03AC Selective beta-2-adrenoceptor agonists 4,1496 R03AC02 Salbutamol(I) 989,816 g 0,8 mg 2,5583 R03AC02 Salbutamol(I) 1754,6 g 0,01 g 0,3628 R03AC04 Fenoterol(I) 63,84 g 0,6 mg 0,2200 R03AC12 Salmeterol(I) 4,98 g 0,1 mg 0,1030 R03AC13 Formoterol(I) 6,6281 g 0,024 mg 0,5710 R03AC18 Indacaterol(I) 24,264 g 0,15 mg 0,3345
R03AK Adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics
11,8364
R03AK06 Salmeterol+Fluticasone(I) 572040 doses 4 doses 0,2957 R03AK06 Salmeterol+Fluticasone(I) 2364240 doses 2 doses 2,4443 R03AK07 Formoterol+Budesonide(I) 1114560 doses 2 doses 1,1523 R03AK07 Formoterol+Budesonide(I) 5776080 doses 4 doses 2,9858 R03AK08 Formoterol+Beclometasone(I) 2948220 doses 4 doses 1,5240 R03AK10 Vilanterol+Fluticasone furoate(I) 1635690 doses 1 doses 3,3821 R03AK13 Salbutamol+Beclometasone(I) 100800 doses 4 doses 0,0521
R03AL Adrenergics in combinations with anticholinergics incl. triple combinations with corticosteroids
3,3915
R03AL01 Fenoterol+Ipratropium bromide(I) 185820 ml 16 ml 0,0240 R03AL01 Fenoterol+Ipratropium bromide(I) 2399000 doses 6 doses 0,8267 R03AL03 Vilanterol+Umeclidinium(I) 326820 doses 1 doses 0,6758 R03AL04 Indacaterol+Glycopyrronium(I) 218220 doses 1 doses 0,4512 R03AL05 Formoterol+Aclidinium(I) 351840 doses 2 doses 0,3638 R03AL06 Olodaterol+Tiotropium(I) 669060 doses 2 doses 0,6917 R03AL07 Formoterol+Glycopyrronium(I) 37920 doses 4 doses 0,0196 R03AL08 Vilanterol+Umeclidinium+Fluticasone furoate(I) 39270 doses 1 doses 0,0812 R03AL09 Formoterol+Glycopyrronium+Beclometasone(I) 498120 doses 4 doses 0,2575
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
4,8834
R03BA Glucocorticoids 1,6251 R03BA01 Beclometasone(I) 0,3 g 1,5 mg 0,0004 R03BA02 Budesonide(I) 160,48 g 1,5 mg 0,2212 R03BA02 Budesonide(I) 312,276 g 0,8 mg 0,8071 R03BA05 Fluticasone(I) 173,037 g 0,6 mg 0,5963 R03BB Anticholinergics 3,2583 R03BB01 Ipratropium bromide(I) 22,028 g 0,12 mg 0,3796 R03BB01 Ipratropium bromide(I) 27,645 g 0,3 mg 0,1905 R03BB04 Tiotropium(I) 3,4869 g 0,005 mg 1,4420 R03BB05 Aclidinium(I) 131,7238 g 0,644 mg 0,4229 R03BB06 Glycopyrronium(I) 8,9866 g 44 mcg 0,4223 R03BB07 Umeclidinium(I) 10,6656 g 55 mcg 0,4010 R03C ADRENERGICS FOR SYSTEMIC USE 0,1451 R03CC Selective beta-2-adrenoceptor agonists 0,1451 R03CC02 Salbutamol(O) 841,8 g 0,012 g 0,1451 R03CC02 Salbutamol(P) 0,1475 g 0,012 g <0,0001
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day R03CC03 Terbutaline(O) 0,5 g 0,015 g 0,0001
R03D OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
2,8850
R03DA Xanthines 1,2529 R03DA04 Theophylline(O) 238710 g 0,4 g 1,2340 R03DA05 Aminophylline(P) 5500,8 g 0,6 g 0,0190 R03DC Leukotriene receptor antagonists 1,5850 R03DC03 Montelukast(O) 7665,672 g 0,01 g 1,5850 R03DX Other systemic drugs for obstructive airway diseases 0,0471 R03DX05 Omalizumab(P) 198 g 0,016 g 0,0256 R03DX09 Mepolizumab(P) 19,8 g 3,6 mg 0,0114 R03DX10 Benralizumab(P) 2,64 g 0,54 mg 0,0101 R05 COUGH AND COLD PREPARATIONS 7,7293
R05C EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS
7,5640
R05CA Expectorants 0,0954 R05CA03 Guaifenesin(O) 41503,2 g 0,9 g 0,0954 R05CA12 Hederae helicis folium(O) 155796 pieces R05CA12 Hederae helicis folium(O) 7816865 ml R05CA86 Iceland moss(O) 9437400 ml
R05CA87 Distillate of rectified essential oils of eucalyptus, sweet orange, myrtle and lemon(O)
1369500 pieces
R05CA88 Thyme herb+Wild thyme+Plantain(O) 489600 ml R05CA89 Thyme herb+Hederae helicis folium(O) 376700 ml R05CA91 Thyme herb+Marshmallow root(O) 5122950 ml R05CA92 Thyme herb(O) 270620 pieces R05CB Mucolytics 7,4687 R05CB01 Acetylcysteine(I, P) 75 g R05CB01 Acetylcysteine(O) 1029638,8 g 0,5 g 4,2580 R05CB01 Acetylcysteine(P) 7065 g R05CB02 Bromhexine(O) 8138 g 0,024 g 0,7011 R05CB03 Carbocisteine(O) 187155 g 1,5 g 0,2580 R05CB06 Ambroxol(O) 129473,7 g 0,12 g 2,2310 R05CB13 Dornase alfa(I) 24,885 g 2,5 mg 0,0206
R05D COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
0,1072
R05DB Other cough suppressants 0,1072 R05DB09 Oxeladin(O) 4148 g 0,08 g 0,1072
R05F COUGH SUPPRESSANTS AND EXPECTORANTS, COMBINATIONS 0,0581
R05FA Opium derivatives and expectorants 0,0581 R05FA80 Codeine+Guaifenesin(O) 842700 ml 30 ml 0,0581 R05X OTHER COLDPREPARATIONS R05XA Other cold combination preparations
R05XA80 Gentian root+Primula flower+Common sorrel+Elder flower+Verbena herb(O)
3764,8 g
R05XA80 Gentian root+Primula flower+Common sorrel+Elder flower+Verbena herb(O)
1815140 pieces
R05XA82 Ibuprofen+Pseudoephedrine(O) 10704 g R06 ANTIHISTAMINES FOR SYSTEMIC USE 17,5952 R06A ANTIHISTAMINES FOR SYSTEMIC USE 17,5952 R06AA Aminoalkyl ethers 0,4752 R06AA02 Diphenhydramine(O) 38 g 0,2 g 0,0004 R06AA02 Diphenhydramine(P) 19 g R06AA04 Clemastine(O) 418,64 g 0,002 g 0,4328 R06AA04 Clemastine(P) 40,64 g 0,002 g 0,0420 R06AE Piperazine derivatives 8,8925 R06AE07 Cetirizine(O) 40649,015 g 0,01 g 8,4051 R06AE09 Levocetirizine(O) 1178,64 g 0,005 g 0,4874 R06AX Other antihistamines for systemic use 8,2275
37/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day R06AX13 Loratadine(O) 18664,5 g 0,01 g 3,8593 R06AX15 Mebhydrolin(O) 20 g 0,2 g 0,0002 R06AX17 Ketotifen(O) 2,37 g 0,002 g 0,0025 R06AX22 Ebastine(O) 7019,3 g 0,01 g 1,4514 R06AX27 Desloratadine(O) 2180,54 g 0,005 g 0,9017 R06AX28 Rupatadine(O) 1049,64 g 0,01 g 0,2170 R06AX29 Bilastine(O) 17365,8 g 20 mg 1,7954 R07 OTHER RESPIRATORY SYSTEM PRODUCTS 0,0004 R07A OTHER RESPIRATORY SYSTEM PRODUCTS 0,0004 R07AA Lung surfactants 0,0004 R07AA81 Porcine lung phospholipids(endotrach) 30,36 g 0,16 g 0,0004 S SENSORY ORGANS 33,3145 S01 OPHTHALMOLOGICALS 33,3145 S01A ANTIINFECTIVES S01AA Antibiotics S01AA01 Chloramphenicol(S) 245840 ml S01AA02 Chlortetracycline(S) 1,25 g S01AA12 Tobramycin(S) 42815 ml S01AA12 Tobramycin(S) 54271 g S01AA13 Fusidic acid(S) 52300 g S01AD Antivirals S01AD02 Trifluridine(S) 5 ml S01AD03 Aciclovir(S) 3397,5 g S01AE Fluoroquinolones S01AE03 Ciprofloxacin(S) 18435 ml S01AE05 Levofloxacin(S) 26495 ml S01AE07 Moxifloxacin(S) 18080 ml S01AX Other antiinfectives S01AX18 Povidone, iodinated(S) 488 ml S01B ANTIINFLAMMATORY AGENTS S01BA Corticosteroids, plain S01BA01 Dexamethasone(S) 90 pieces S01BA01 Dexamethasone(S) 14680,3 g S01BA01 Dexamethasone(S) 156465 ml S01BA02 Hydrocortisone(S) 4143 g S01BA09 Clobetasone(S) 33500 ml S01BA14 Loteprednol(S) 6595 ml S01BC Antiinflammatory agents, non-steroids S01BC03 Diclofenac(S) 50 ml S01BC05 Ketorolac(S) 6500 ml S01BC10 Nepafenac(S) 20630 ml S01BC11 Bromfenac(S) 10470 ml
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
S01CA Corticosteroids and antiinfectives in combination S01CA80 Dexamethasone+Neomycin+Polymyxin B(S) 59170 ml S01CA81 Dexamethasone+Tobramycin(S) 15708 g S01CA81 Dexamethasone+Tobramycin(S) 43765 ml S01CA82 Dexamethasone+Chloramphenicol(S) 49059,5 g S01CA82 Dexamethasone+Chloramphenicol(S) 477140 ml S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS 33,3145 S01EA Sympathomimetics in glaucoma therapy 0,0183 S01EA05 Brimonidine(S) 1770 ml 0,2 ml 0,0183 S01EB Parasympathomimetics 0,0136 S01EB01 Pilocarpine(S) 2010 ml 0,4 ml 0,0104 S01EB02 Carbachol(S) 624 ml 0,4 ml 0,0032 S01EC Carbonic anhydrase inhibitors 3,7336 S01EC01 Acetazolamide(O) 25465 g 0,75 g 0,0702 S01EC01 Acetazolamide(P) 104,5 g 0,75 g 0,0003 S01EC03 Dorzolamide(S) 136500 ml 0,3 ml 0,9408
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day S01EC04 Brinzolamide(S) 162820 ml 0,2 ml 1,6833 S01EC80 Brinzolamide+Brimonidine(S) 100490 ml 0,2 ml 1,0389 S01ED Beta blocking agents 20,6756 S01ED01 Timolol(S) 23420 ml 0,2 ml 0,2421 S01ED01 Timolol(S) 219055 g 40 mg 11,3236 S01ED02 Betaxolol(S) 94910 ml 0,2 ml 0,9812 S01ED80 Timolol+Dorzolamide(S) 308050 ml 0,2 ml 3,1848 S01ED81 Timolol+Travoprost(S) 46380 ml 0,2 ml 0,4795 S01ED82 Timolol+Bimatoprost(S) 118551 ml 0,2 ml 1,2257 S01ED83 Timolol+Brinzolamide(S) 234105 ml 0,2 ml 2,4203 S01ED84 Timolol+Latanoprost(S) 72285 ml 0,2 ml 0,7473 S01ED85 Timolol+Tafluprost(S) 6869,7 ml 0,2 ml 0,0710 S01EE Prostaglandin analogues 8,8734 S01EE01 Latanoprost(S) 280272,5 ml 0,1 ml 5,7952 S01EE03 Bimatoprost(S) 255 ml 0,1 ml 0,0053 S01EE04 Travoprost(S) 73700 ml 0,1 ml 1,5239 S01EE05 Tafluprost(S) 224739 ml 0,3 ml 1,5490 S01F MYDRIATICS AND CYCLOPLEGICS S01FA Anticholinergics S01FA01 Atropine(S) 230 ml S01FA04 Cyclopentolate(S) 34620 ml S01FA06 Tropicamide(S) 17985 ml S01FB Sympathomimetics excl. antiglaucoma preparations S01FB01 Phenylephrine(S) 8595 ml S01G DECONGESTANTS AND ANTIALLERGICS S01GA Sympathomimetics used as decongestants S01GA02 Tetryzoline(S) 311940 ml S01GX Other antiallergics S01GX01 Cromoglicic acid(S) 117340 ml S01GX07 Azelastine(S) 40794 ml S01GX09 Olopatadine(S) 20210 ml S01H LOCAL ANESTHETICS S01HA Local anesthetics S01HA03 Tetracaine(S) 18280 ml S01HA04 Proxymetacaine(S) 46275 ml S01J DIAGNOSTIC AGENTS S01JA Colouring agents S01JA01 Fluorescein(P) 6120 ml S01JA81 Fluorescein+Oxybuprocaine+Chlorobutanol(S) 2825 ml S01K SURGICAL AIDS S01KA Viscoelastic substances S01KA02 Hypromellose(S) 5760 g S01L OCULAR VASCULAR DISORDER AGENTS S01LA Antineovascularisation agents S01LA01 Verteporfin(P) 3 pieces S01LA04 Ranibizumab(S) 4 pieces S01LA05 aflibercept(S) 228 pieces S01X OTHER OPHTHALMOLOGICALS S01XA Other ophthalmologicals S01XA03 Sodium chloride(S) 598,5 g S01XA18 Ciclosporin(S) 2484 ml S01XA80 Retinol+Dexpanthenol(S) 9457 g S01XA81 Carbomer(S) 191970 g S01XA82 Hypromellose(S) 195910 ml S01XA85 Hypromellose+Dextran(S) 457785 ml S02 OTOLOGICALS
S02C CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION
S02CA Corticosteroids and antiinfectives in combination S02CA81 Dexamethasone+Neomycin+Acetic acid, glacial(A) 3130 ml
39/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day S02CA82 Hydrocortisone+Ciprofloxacin(A) 134260 ml S02D OTHER OTOLOGICALS S02DA Analgesics and anesthetics S02DA81 Phenazone+Lidocaine(A) 1005 ml T HERBAL MEDICINAL PRODUCTS T01 HERBAL MEDICINAL PRODUCTS T01R HERBAL MEDICINAL PRODUCTS T01RS Herbal medicinal products T01RS01 herbal preparation(O) 716180 pieces T01RS01 herbal preparation(O) 8394970 ml T01RS02 homeopathic preparations(A) 7460 ml T01RS02 homeopathic preparations(C) 582550 g T01RS02 homeopathic preparations(O) 1540 g T01RS02 homeopathic preparations(O) 1194750 pieces T01RS02 homeopathic preparations(O) 1512010 ml V VARIOUS 0,2168 V01 ALLERGENS V01A ALLERGENS V01AA Allergen extracts V01AA02 Grass pollen(O) 136 pieces V01AA02 Grass pollen(P) 93 pieces V01AA03 House dust mites(O) 341 pieces V01AA03 House dust mites(P) 3 ml V01AA03 House dust mites(P) 258 pieces V01AA05 Tree pollen(P) 419 pieces V01AA05 Tree pollen(SL) 755 pieces V01AA07 Allergen products (insects)(P) 318 pieces V01AA10 Flowers(O) 7 pieces V01AA11 Animals(O) 29 pieces V01AA80 Tree and grass pollen(O) 162 pieces V01AA80 Tree and grass pollen(P) 57 pieces V01AA83 Grass pollen+Flowers(O) 24 pieces V01AA84 Tree and flower pollen(O) 33 pieces V03 ALL OTHER THERAPEUTIC PRODUCTS 0,2168 V03A ALL OTHER THERAPEUTIC PRODUCTS 0,2168 V03AB Antidotes V03AB14 Protamine sulfate(P) 275 g V03AB15 Naloxone(N) 1,8792 g V03AB15 Naloxone(P) 1,096 g V03AB16 Ethanol(P) 12500 ml V03AB17 Methylthioninium chloride(P) 157,5 g V03AB19 Physostigmine(P) 0,07 g V03AB24 Digitalis antitoxin(P) 1 g V03AB25 Flumazenil(P) 0,225 g V03AB33 Hydroxocobalamin(P) 40 g V03AB34 Fomepizole(P) 40 g V03AB35 Sugammadex(P) 66 g V03AB37 Idarucizumab(P) 225 g V03AC Iron chelating agents V03AC01 Deferoxamine(P) 7,5 g V03AC03 Deferasirox(O) 5929,2 g V03AE Drugs for treatment of hyperkalemia and hyperphosphatemia 0,1461 V03AE01 Polystyrene sulfonate(O, R) 1828723 g 45 g 0,0840 V03AE02 Sevelamer(O) 135792 g 6,4 g 0,0439 V03AE03 Lanthan(O) 19845 g 2,25 g 0,0182 V03AF Detoxifying agents for antineoplastic treatment 0,0707 V03AF01 Mesna(P) 5412 g V03AF03 Calcium folinate(O) 30,15 g 0,06 g 0,0010 V03AF07 Rasburicase(P) 0,6165 g 0,014 g 0,0001 V03AF09 Glucarpidase(P) 22000 U
40/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day V03AF10 Sodium levofolinate(P) 1009,3 g 0,03 g 0,0696 V03AH Drugs for treatment of hypoglycemia V03AH01 Diazoxide(O) 55 g V03AN Medical gases V03AN01 Oxygen(I) 488368000 ml V03AN05 Air, medicinal(I) 2730000 ml V03AX Other therapeutic products V03AX01 Yohimbic acid(O) 0,25 g V04 DIAGNOSTIC AGENTS V04C OTHER DIAGNOSTIC AGENTS V04CD Tests for pituitary function V04CD01 Metyrapone(O) 12,5 g V04CD04 Corticorelin(P) 0,0002 g V04CF Tuberculosis diagnostics V04CF01 Tuberculin(P) 3600 U V04CJ Tests for thyreoidea function V04CJ02 Protirelin(P) 0,005 g V04CL Tests for allergic diseases V04CL83 Benzylpenicilloyl polylysine(P) 5 pieces V04CX Other diagnostic agents V04CX01 Indocyanine green(P) 6,625 g V04CX03 Methacholine(I) 45,036 g V04CX06 Hexaminolevulinate(P) 27,37 g V04CX09 Patent blue(P) 2,5 g V04CX87 Carbon monoxide+Helium(I) 20000 ml V07 ALL OTHER NON-THERAPEUTIC PRODUCTS V07A ALL OTHER NON-THERAPEUTIC PRODUCTS V07AB Solvents and diluting agents, incl. irrigating solutions V07AB80 Sodium chloride(P) 7171200 ml V07AB83 Water for injection(NA) 13359950 ml V08 CONTRAST MEDIA V08A X-RAY CONTRAST MEDIA, IODINATED
V08AA Watersoluble, nephrotropic, high osmolar X-ray contrast media
V08AA01 Sodium amidotrizoate+Meglumine Amidotrizoate(P) 6000 ml V08AB Watersoluble, nephrotropic, low osmolar X-ray contrast media V08AB02 Iohexol(P) 1748980 g V08AB05 Iopromide(P) 1216456,5 g V08AB09 Iodixanol(P) 2589464 g V08AD Non-watersoluble X-ray contrast media V08AD01 Ethyl esters of iodised fatty acids(P) 76,8 g V08B X-RAY CONTRAST MEDIA, NON-IODINATED V08BA Barium sulfate containing X-ray contrast media V08BA01 Barium sulfate(O) 151388,8 g V08BA01 Barium sulfate(O, R) 10400 g V08C MAGNETIC RESONANCE IMAGING CONTRAST MEDIA V08CA Paramagnetic contrast media V08CA01 Gadopentetic acid(P) 3520 ml V08CA02 Gadoteric acid(P) 47250 ml V08CA09 Gadobutrol(P) 80180 ml V08CA10 Gadoxetic acid(P) 4090 ml V08D ULTRASOUND CONTRAST MEDIA V08DA Ultrasound contrast media V08DA05 Sulfur hexafluoride, phospholipid microspheres(P) 200 ml V09 DIAGNOSTIC RADIOPHARMACEUTICALS V09A CENTRAL NERVOUS SYSTEM V09AB Iodine (123I) compounds V09AB03 Ioflupane (123I)(P) 175 ml
41/41
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A ALIMENTARY TRACT AND METABOLISM 195,7240
A01 STOMATOLOGICAL PREPARATIONS 0,0712
A01A STOMATOLOGICAL PREPARATIONS 0,0712
A01AA Caries prophylactic agents
A01AA01 Sodium fluoride (dental) 1 pieces
A01AB Antiinfectives and antiseptics for local oral treatment 0,0712
A01AB09 Miconazole (O) 6921,6 g 0,2 g 0,0712
A01AB12 Hexetidine (O) 631960 ml
A01AB82 Demeclocycline+ Triamcinolone (dental) 415 g
A01AD Other agents for local oral treatment
A01AD80 Lidocaine+ Cetylpyridinium chloride (gingival) 220680 g
A01AD81 Lidocaine+ Cetrimide (O) 67725 g
A01AD82 Choline salicylate (O) 648896 pieces
A01AD83 Lidocaine+ Chamomillae extractum (O) 379450 g
A02 DRUGS FOR ACID RELATED DISORDERS 66,8968
A02A ANTACIDS 1,3880
A02AD Combinations and complexes of aluminium, calcium and
magnesium compounds 1,3880
A02AD81 Aluminium hydroxide+ Magnesium hydroxide (O) 2198600 pieces 10 pieces 0,4522
A02AD81 Aluminium hydroxide+ Magnesium hydroxide (O) 5200710 ml 50 ml 0,2139
A02AD83 Calcium carbonate+ Magnesium carbonate (O) 3509592 pieces 10 pieces 0,7219
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-
OESOPHAGEAL REFLUX DISEASE (GORD) 65,5087
A02BA H2-receptor antagonists 0,0104
A02BA02 Ranitidine (P) 3,25 g 0,3 g <0,0001
A02BA03 Famotidine (O) 201,6 g 0,04 g 0,0104
A02BC Proton pump inhibitors 65,4802
A02BC01 Omeprazole (O) 313399,56 g 0,02 g 32,2308
A02BC02 Pantoprazole (O) 343352,52 g 0,04 g 17,6556
A02BC02 Pantoprazole (P) 12 g 0,04 g 0,0006
A02BC03 Lansoprazole (O) 15,12 g 0,03 g 0,0010
A02BC05 Esomeprazole (O) 219529,8 g 0,03 g 15,0513
A02BC05 Esomeprazole (P) 7887,6 g 0,03 g 0,5408
A02BC08 Vonoprazan (O) 2 g
A02BD Combinations for eradication of Helicobacter pylori 0,0031
A02BD08 Bismuth subcitrate+ Tetracycline+ Metronidazole (O) 18000 pieces 12 pieces 0,0031
A02BX Other drugs for peptic ulcer and gastro-oesophageal
reflux disease (GORD) 0,0151
A02BX02 Sucralfate (O) 29220 g 4 g 0,0150
A02BX05 Bismuth subcitrate (O) 6 g 0,48 g <0,0001
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL
DISORDERS 9,1480
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL
DISORDERS 8,1562
A03AA Synthetic anticholinergics, esters with tertiary amino
group 1,4403
A03AA04 Mebeverine (O) 210078 g 0,3 g 1,4403
A03AB Synthetic anticholinergics, quaternary ammonium
compounds 0,0002
A03AB02 Glycopyrronium (P) 0,028 g 0,3 mg 0,0002
A03AD Papaverine and derivatives 5,0731
A03AD01 Papaverine hydrochloride (P) 66,4 g 0,1 g 0,0014
A03AD02 Drotaverine (O) 243003,84 g 0,1 g 4,9982
A03AD02 Drotaverine (P) 3575 g 0,1 g 0,0735
A03AX Other drugs for functional gastrointestinal disorders 1,6426
A03AX13 Simeticone (O) 399293,125 g 0,5 g 1,6426
A03B BELLADONNA AND DERIVATIVES, PLAIN 0,0856
A03BA Belladonna alkaloids, tertiary amines 0,0739
1/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A03BA01 Atropine (O, P) 9,76 g 0,0015 g 0,0134
A03BA01 Atropine (P) 44,11 g 0,0015 g 0,0605
A03BB Belladonna alkaloids, semisynthetic, quaternary
ammonium compounds 0,0118
A03BB01 Hyoscine butylbromide (O) 8,4 g 0,06 g 0,0003
A03BB01 Hyoscine butylbromide (P) 335 g 0,06 g 0,0115
A03F PROPULSIVES 0,9061
A03FA Propulsives 0,9061
A03FA01 Metoclopramide (O) 11435 g 0,03 g 0,7840
A03FA01 Metoclopramide (P) 1568,4 g 0,03 g 0,1075
A03FA03 Domperidone (O) 212,4 g 0,03 g 0,0146
A04 ANTIEMETICS AND ANTINAUSEANTS 0,1376
A04A ANTIEMETICS AND ANTINAUSEANTS 0,1376
A04AA Serotonin (5-HT3) antagonists 0,1284
A04AA01 Ondansetron (P) 233,36 g 0,016 g 0,0300
A04AA02 Granisetron (O) 67 g 0,002 g 0,0689
A04AA02 Granisetron (P) 39,265 g 0,003 g 0,0269
A04AA80 Palonosetron+ Netupitant (O) 1235 pieces 1 pieces 0,0025
A04AD Other antiemetics 0,0092
A04AD01 Scopolamine (TD) 10 pieces 1 pieces <0,0001
A04AD12 Aprepitant (O) 190,095 g 0,165 g 0,0024
A04AD81 Fosaprepitant (P) 316,65 g 0,095 g 0,0069
A05 BILE AND LIVER THERAPY 1,8146
A05A BILE THERAPY 0,6209
A05AA Bile acids and derivatives 0,6209
A05AA02 Ursodeoxycholic acid (O) 226387,5 g 0,75 g 0,6209
A05B LIVER THERAPY, LIPOTROPICS 1,1937
A05BA Liver therapy 1,1937
A05BA03 Silymarin (O) 1886850 pieces
A05BA03 Silymarin (P) 28 g
A05BA80 Phospholipids from Soya Beans (O) 1017710 pieces 6 pieces 0,3489
A05BA80 Phospholipids from Soya Beans (O) 1232250 pieces 3 pieces 0,8449
A06 DRUGS FOR CONSTIPATION 17,9700
A06A DRUGS FOR CONSTIPATION 17,9700
A06AB Contact laxatives 7,5544
A06AB02 Bisacodyl (O) 14349,8 g 0,01 g 2,9515
A06AB02 Bisacodyl (R) 166,08 g 0,01 g 0,0342
A06AB06 Sennoside A (O) 460 pieces 1 pieces 0,0009
A06AB08 Sodium picosulfate (O) 11091,3849 g 0,005 g 4,5627
A06AB80 Sodium picosulfate+ Magnesium oxide+ Citric acid (O) 4922 pieces 2 pieces 0,0051
A06AD Osmotically acting laxatives 9,3124
A06AD11 Lactulose (O) 28355286 g 6,7 g 8,7049
A06AD15 Macrogol (O) 2953920 g 10 g 0,6076
A06AD80 Macrogol+ Sodium citrate+ Citric acid+ Sodium chloride+
Potassium chloride (O) 2400 ml
A06AD81 Sodium sulfate anhydrous+ Potassium chloride+ Sodium
chloride+ Macrogol+ Sodium hydrogen carbonate (O) 35656 pieces
A06AD83
Macrogol+ Sodium sulfate anhydrous+ Sodium chloride+
Potassium chloride+ Ascorbic acid+ Sodium ascorbate
(O)
7855 pieces
A06AD85 Sodium sulfate anhydrous+ magnesium sulfate
heptahydrate+ Potassium sulphate (O) 790944 ml
A06AG Enemas 1,0533
A06AG11 Sodium lauryl sulfoacetate+ Sorbitol+ Sodium citrate (R) 512116 pieces 1 pieces 1,0533
A06AH Peripheral opioid receptor antagonists 0,0497
A06AH03 Naloxegol (O) 603,75 g 25 mg 0,0497
A06AX Other drugs for constipation 0,0002
A06AX06 Tegaserod (O) 1,08 g 12 mg 0,0002
2/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A07 ANTIDIARRHEALS, INTESTINAL
ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS 4,9266
A07A INTESTINAL ANTIINFECTIVES 0,0082
A07AA Antibiotics 0,0082
A07AA02 Nystatin (O) 90000000 U 1500000 U 0,0001
A07AA11 Rifaximin (O) 2200,8 g 0,6 g 0,0075
A07AA12 Fidaxomicin (O) 108 g 0,4 g 0,0006
A07B INTESTINAL ADSORBENTS 0,5120
A07BC Other intestinal adsorbents 0,5120
A07BC05 Diosmectite (O) 2240220 g 9 g 0,5120
A07C ELECTROLYTES WITH CARBOHYDRATES
A07CA Oral rehydration salt formulations
A07CA80 Sodium chloride+ Potassium chloride+ Sodium citrate+
Glucose (O) 107820 pieces
A07D ANTIPROPULSIVES 1,0396
A07DA Antipropulsives 1,0396
A07DA03 Loperamide (O) 5054,564 g 0,01 g 1,0396
A07E INTESTINAL ANTIINFLAMMATORY AGENTS 2,5534
A07EA Corticosteroids acting locally 0,0319
A07EA06 Budesonide (O) 139,62 g 0,009 g 0,0319
A07EA06 Budesonide (R) 1,0619 g
A07EC Aminosalicylic acid and similar agents 2,5215
A07EC01 Sulfasalazine (O) 749300 g 2 g 0,7706
A07EC02 Mesalazine (O) 1167564 g 1,5 g 1,6010
A07EC02 Mesalazine (R) 109310 g 1,5 g 0,1499
A07F ANTIDIARRHEAL MICROORGANISMS 0,8134
A07FA Antidiarrheal microorganisms 0,8134
A07FA02 Saccharomyces boulardii (O) 395457,5 g 1 g 0,8134
A07X OTHER ANTIDIARRHEALS
A07XA Other antidiarrheals
A07XA04 Racecadotril (O) 2626 g
A08 ANTIOBESITY PREPARATIONS, EXCL. DIET
PRODUCTS 0,0035
A08A ANTIOBESITY PREPARATIONS, EXCL. DIET
PRODUCTS 0,0035
A08AA Centrally acting antiobesity products 0,0031
A08AA62 Bupropion+ Naltrexone (O) 6048 pieces 4 pieces 0,0031
A08AB Peripherally acting antiobesity products 0,0003
A08AB01 Orlistat (O) 60,48 g 0,36 g 0,0003
A09 DIGESTIVES, INCL. ENZYMES 1,8593
A09A DIGESTIVES, INCL. ENZYMES 1,8593
A09AA Enzyme preparations 1,8593
A09AA02 Lipase+ Amylase+ Protease (O) 3615886 pieces 4 pieces 1,8593
A10 DRUGS USED IN DIABETES 73,7920
A10A INSULINS AND ANALOGUES 15,9233
A10AB Insulins and analogues for injection, fast-acting 6,1766
A10AB01 Insulin human rapid-acting (P) 1054500 U 40 U 0,0542
A10AB04 Insulin lispro (P) 18876000 U 40 U 0,9706
A10AB05 Insulin aspart (P) 88759500 U 40 U 4,5641
A10AB06 Insulin glulisine (P) 11427000 U 40 U 0,5876
A10AC Insulins and analogues for injection, intermediate-acting 0,0421
A10AC01 Insulin human intermediate-acting (P) 819000 U 40 U 0,0421
A10AD Insulins and analogues for injection, intermediate- or long-
acting combined with fast-acting 0,7257
A10AD04 Insulin lispro (P) 2949000 U 40 U 0,1516
A10AD05 Insulin aspart (P) 7050000 U 40 U 0,3625
A10AD06 Insulin degludec+ Insulin aspart (P) 4114500 U 40 U 0,2116
A10AE Insulins and analogues for injection, long-acting 8,9789
A10AE04 Insulin glargine (P) 89067750 U 40 U 4,5800
A10AE05 Insulin detemir (P) 29962500 U 40 U 1,5407
3/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A10AE06 Insulin degludec (P) 52365300 U 40 U 2,6927
A10AE54 Insulin glargine+ Lixisenatide (P) 3219000 U 40 U 0,1655
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL.
INSULINS 57,8687
A10BA Biguanides 21,2384
A10BA02 Metformin (O) 20651358 g 2 g 21,2384
A10BB Sulfonylureas 10,7837
A10BB01 Glibenclamide (O) 0,054 g 0,01 g <0,0001
A10BB07 Glipizide (O) 650,85 g 0,01 g 0,1339
A10BB08 Gliquidone (O) 16,2 g 0,06 g 0,0006
A10BB09 Gliclazide (O) 179014,2 g 0,06 g 6,1368
A10BB12 Glimepiride (O) 4387,77 g 0,002 g 4,5125
A10BD Combinations of oral blood glucose lowering drugs 8,8691
A10BD07 Metformin+ Sitagliptin (O) 1368640 pieces 2 pieces 1,4075
A10BD08 Metformin+ Vildagliptin (O) 1349640 pieces 2 pieces 1,3880
A10BD10 Metformin+ Saxagliptin (O) 265920 pieces 2 pieces 0,2735
A10BD11 Metformin+ Linagliptin (O) 1351920 pieces 2 pieces 1,3903
A10BD15 Metformin+ Dapagliflozin (O) 1222648 pieces 2 pieces 1,2574
A10BD19 Linagliptin+ Empagliflozin (O) 292170 pieces 1 pieces 0,6010
A10BD20 Metformin+ Empagliflozin (O) 2272560 pieces 2 pieces 2,3372
A10BD21 Saxagliptin+ Dapagliflozin (O) 102928 pieces 1 pieces 0,2117
A10BD23 Metformin+ Ertugliflozin (O) 1232 pieces 1 pieces 0,0025
A10BF Alpha glucosidase inhibitors 0,0001
A10BF01 Acarbose (O) 21 g 0,3 g 0,0001
A10BG Thiazolidinediones 0,1191
A10BG03 Pioglitazone (O) 1737,54 g 0,03 g 0,1191
A10BH Dipeptyl peptidase 4 (DPP-4) inhibitors 4,2405
A10BH01 Sitagliptin (O) 35821,1 g 0,1 g 0,7368
A10BH02 Vildagliptin (O) 7689 g 0,1 g 0,1582
A10BH03 Saxagliptin (O) 448,65 g 5 mg 0,1846
A10BH05 Linagliptin (O) 7684,05 g 5 mg 3,1610
A10BJ Glucagon-like peptide-1 (GLP-1) analogues 7,1421
A10BJ01 Exenatide (P) 2,608 g 0,286 mg 0,0188
A10BJ02 Liraglutide (P) 350,892 g 1,5 mg 0,4812
A10BJ03 Lixisenatide (P) 0,3252 g 20 mcg 0,0334
A10BJ05 Dulaglutide (P) 50,31 g 0,16 mg 0,6468
A10BJ06 Semaglutide (O) 2953,74 g 10,5 mg 0,5786
A10BJ06 Semaglutide (P) 287,9 g 0,11 mg 5,3833
A10BK Sodium-glucose co-transporter 2 (SGLT2) inhibitors 5,4757
A10BK01 Dapagliflozin (O) 12969,45 g 10 mg 2,6676
A10BK03 empagliflozin (O) 23887,8 g 17,5 mg 2,8076
A10BK04 Ertugliflozin (O) 1,96 g 10 mg 0,0004
A11 VITAMINS 9,3214
A11A MULTIVITAMINS, COMBINATIONS 1,1303
A11AA Multivitamins with minerals 1,1303
A11AA03 Multivitamins+ Mineral elements (O) 549540 pieces 1 pieces 1,1303
A11C VITAMIN A AND D, INCL. COMBINATIONS OF THE
TWO 2,1840
A11CA Vitamin A, plain <0,0001
A11CA01 Retinol (P) 1200000 U 50000 U <0,0001
A11CC Vitamin D and analogues 2,1839
A11CC03 Alfacalcidol (O) 0,0003 g 0,001 mg 0,0007
A11CC04 Calcitriol (O) 0,0976 g 0,001 mg 0,2007
A11CC05 Colecalciferol (O) 771100000 U 800 U 1,9825
A11CC05 Colecalciferol (P) 65000000 U
A11D VITAMIN B1, PLAIN AND IN COMBINATION WITH
VITAMIN B6 AND B12 1,5661
A11DA Vitamin B1, plain 0,4634
A11DA01 Thiamine (P) 11264 g 0,05 g 0,4634
4/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A11DA03 Benfotiamine (O) 1759570 pieces
A11DB Vitamin B1 in combination with vitamin B6 and/or vitamin
B12 1,1027
A11DB80 Thiamine+ Pyridoxine (P) 5610 pieces 1 pieces 0,0115
A11DB81 Benfotiamine+ Pyridoxine (O) 216930 pieces 3 pieces 0,1487
A11DB84 Thiamine+ Pyridoxine+ Cyanocobalamin (O) 394660 pieces 1 pieces 0,8118
A11DB85 Thiamine+ Pyridoxine+ Cyanocobalamin+ Lidocaine (P) 63530 pieces 1 pieces 0,1307
A11E VITAMIN B-COMPLEX, INCL. COMBINATIONS 0,4422
A11EA Vitamin B-complex, plain 0,4422
A11EA80 Thiamine+ Nicotinamide+ Riboflavin+ Calcium
pantothenate+ Pyridoxine (O) 215000 pieces 1 pieces 0,4422
A11EA80 Thiamine+ Nicotinamide+ Riboflavin+ Calcium
pantothenate+ Pyridoxine (P) 552 pieces
A11G ASCORBIC ACID (VITAMIN C), INCL. COMBINATIONS 0,1701
A11GA Ascorbic acid (vitamin C), plain 0,1701
A11GA01 Ascorbic acid (P) 16535 g 0,2 g 0,1701
A11H OTHER PLAIN VITAMIN PREPARATIONS 0,0554
A11HA Other plain vitamin preparations 0,0554
A11HA02 Pyridoxine (O) 240 g 0,16 g 0,0031
A11HA02 Pyridoxine (P) 3829,5 g 0,16 g 0,0492
A11HA03 Tocopherol (P) 4,5 g 0,2 g <0,0001
A11HA05 Biotin (P) 12 ml
A11HA08 Tocofersolan (O) 294 g 0,2 g 0,0030
A11J OTHER VITAMIN PRODUCTS, COMBINATIONS 3,7734
A11JA Combinations of vitamins
A11JA80 Combinations of vitamins (O) 600 ml
A11JB Vitamins with minerals 3,7734
A11JB81 Pyridoxine+ Magnesium (O) 7338180 pieces 4 pieces 3,7734
A12 MINERAL SUPPLEMENTS 9,0667
A12A CALCIUM 5,4290
A12AA Calcium 0,9629
A12AA03 Calcium gluconate (P) 41340 g 3 g 0,0283
A12AA04 Calcium carbonate (O) 1363050 g 3 g 0,9345
A12AX Calcium, combinations with vitamin D and/or other drugs 4,4661
A12AX80 Calcium+ Colecalciferol (O) 577320 pieces 1 pieces 1,1875
A12AX80 Calcium+ Colecalciferol (O) 3188040 pieces 2 pieces 3,2787
A12B POTASSIUM 3,2030
A12BA Potassium 3,2030
A12BA01 Potassium chloride (O) 405066 g 3 g 0,2777
A12BA02 Potassium citrate (O) 1080 g 4 g 0,0006
A12BA80 Potassium chloride+ Potassium hydrogen carbonate (O) 4500 pieces
A12BA81 Potassium aspartate+ Magnesium aspartate (O) 4228100 pieces 3 pieces 2,8989
A12BA81 Potassium aspartate+ Magnesium aspartate (P) 12600 pieces 1 pieces 0,0259
A12C OTHER MINERAL SUPPLEMENTS 0,4346
A12CB Zinc
A12CB02 Zinc gluconate (P) 9,061 g
A12CC Magnesium 0,4345
A12CC04 Magnesium citrate (O) 422494 g 2 g 0,4345
A12CE Selenium 0,0001
A12CE02 Sodium selenite (P) 0,01 g 0,2 mg 0,0001
A12CX Other mineral products
A12CX83 Phosphate (O) 13500 pieces
A14 ANABOLIC AGENTS FOR SYSTEMIC USE 0,0044
A14A ANABOLIC STEROIDS 0,0044
A14AB Estren derivatives 0,0044
A14AB01 Nandrolone (P) 4,25 g 0,002 g 0,0044
5/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A16 OTHER ALIMENTARY TRACT AND METABOLISM
PRODUCTS 0,7120
A16A OTHER ALIMENTARY TRACT AND METABOLISM
PRODUCTS 0,7120
A16AA Amino acids and derivatives 0,0028
A16AA01 Levocarnitine (O) 1800 g 2 g 0,0019
A16AA02 Ademetionine (O) 810 g
A16AA05 Carglumic acid (O) 12 g 0,2 g 0,0001
A16AA06 Betaine (O) 2520 g 6 g 0,0009
A16AA81 Glycine (O) 480 g
A16AB Enzymes 0,0046
A16AB03 Agalsidase alfa (P) 1,316 g 0,001 g 0,0027
A16AB04 Agalsidase beta (P) 1,755 g 0,005 g 0,0007
A16AB07 Alglucosidase alfa (P) 54,7 g 0,1 g 0,0011
A16AB09 Idursulfase (P) 1,344 g
A16AX Various alimentary tract and metabolism products 0,7046
A16AX01 Thioctic acid (O) 201384 g 0,6 g 0,6904
A16AX01 Thioctic acid (P) 375 g 0,6 g 0,0013
A16AX05 Zinc (O) 650 g 0,15 g 0,0089
A16AX06 Miglustat (O) 218,4 g 0,3 g 0,0015
A16AX07 Sapropterin (O) 888 g
A16AX10 Eliglustat (O) 206,976 g 0,168 g 0,0025
A16AX80 Creatine (O) 6750 g
A16AX81 Copper histidinate (P) 0,19 g
B BLOOD AND BLOOD FORMING ORGANS 116,1519
B01 ANTITHROMBOTIC AGENTS 82,2564
B01A ANTITHROMBOTIC AGENTS 82,2564
B01AA Vitamin K antagonists 1,2187
B01AA03 Warfarin (O) 4443,8 g 0,0075 g 1,2187
B01AB Heparin group 3,1306
B01AB01 Heparin sodium (P) 567000000 U 10000 U 0,1166
B01AB05 Enoxaparin sodium (hem, P) 973076000 U 2000 U 1,0007
B01AB05 Enoxaparin sodium (P) 1896468000 U 2000 U 1,9504
B01AB12 Bemiparin sodium (P) 76365000 U 2500 U 0,0628
B01AC Platelet aggregation inhibitors, excl. heparin 51,8484
B01AC04 Clopidogrel (O) 146181,3 g 0,075 g 4,0090
B01AC06 Acetylsalicylic acid (O) 4753972 pieces 1 pieces 9,7782
B01AC09 Epoprostenol (P) 0,005 g
B01AC11 Iloprost (I) 0,0084 g 0,15 mg 0,0001
B01AC11 Iloprost (P) 0,0057 g 50 mcg 0,0002
B01AC16 Eptifibatide (P) 68,69 g 0,2 g 0,0007
B01AC21 Treprostinil (P) 7,82 g 0,0043 g 0,0037
B01AC23 Cilostazol (O) 84 g 0,2 g 0,0009
B01AC24 Ticagrelor (O) 102105,36 g 0,18 g 1,1668
B01AC27 Selexipag
(O) 1,932 g 1,8 mg 0,0022
B01AC80 Acetylsalicylic acid + Magnesium oxide (O) 17933500 pieces 1 pieces 36,8865
B01AD Enzymes 0,0030
B01AD01 Streptokinase (P) 135000000 U 1500000 U 0,0002
B01AD02 Alteplase (P) 116,4 g 0,1 g 0,0024
B01AD11 Tenecteplase (P) 8,11 g 0,04 g 0,0004
B01AE Direct thrombin inhibitors 2,5655
B01AE07 Dabigatran etexilate (O) 374190,6 g 0,3 g 2,5655
B01AF Direct factor Xa inhibitors 23,4886
B01AF01 Rivaroxaban (O) 108453,9088 g 0,02 g 11,1537
B01AF02 Apixaban (O) 51183,75 g 10 mg 10,5277
B01AF03 Edoxaban (O) 52718,4 g 60 mg 1,8072
B01AX Other antithrombotic agents 0,0016
B01AX01 Defibrotide (P) 8 g 1,75 g <0,0001
B01AX05 Fondaparinux sodium (P) 1,925 g 0,0025 g 0,0016
B02 ANTIHEMORRHAGICS 0,2310
6/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B02A ANTIFIBRINOLYTICS 0,2000
B02AA Amino acids 0,2000
B02AA01 Aminocaproic acid (P) 3430 g 16 g 0,0004
B02AA02 Tranexamic acid (O) 147200 g 2 g 0,1514
B02AA02 Tranexamic acid (P) 46800 g 2 g 0,0481
B02B VITAMIN K AND OTHER HEMOSTATICS 0,0310
B02BA Vitamin K 0,0032
B02BA01 Phytomenadione (O) 0,9 g 0,02 g 0,0001
B02BA01 Phytomenadione (O, P) 3,77 g 0,02 g 0,0004
B02BA01 Phytomenadione (P) 26,51 g 0,02 g 0,0027
B02BB Fibrinogen 0,0002
B02BB01 Fibrinogen human (P) 510 g 5 g 0,0002
B02BC Local hemostatics
B02BC81 Fibrinogen human+ Human thrombin (epil) 663 pieces
B02BD Blood coagulation factors
B02BD01 Human prothrombin complex (P) 247800 U
B02BD02 Human coagulation factor VIII (P) 7476000 U
B02BD03 Factor VIII inhibitor bypassing fraction (P) 45000 U
B02BD04 Human coagulation factor IX (P) 391200 U
B02BD05 Human coagulation factor VII (P) 370800 U
B02BD06 Von Willebrand factor+ Human coagulation factor VIII (P) 1516000 U
B02BD08 Coagulation factor VIIa (P) 77500000 U
B02BX Other systemic hemostatics 0,0276
B02BX01 Etamsylate (P) 382,5 g
B02BX04 Romiplostim (P) 0,089 g 30 mcg 0,0061
B02BX05 Eltrombopag (O) 394,1 g 50 mg 0,0162
B02BX06 Emicizumab (P) 38,685 g 15 mg 0,0053
B03 ANTIANEMIC PREPARATIONS 33,6611
B03A IRON PREPARATIONS 4,2823
B03AA Iron bivalent, oral preparations 1,9675
B03AA07 Ferrous sulfate (O) 191316 g 0,2 g 1,9675
B03AB Iron trivalent, oral preparations
B03AB80 Ferric hydroxide polymaltose complex (O) 86055 g
B03AC Iron, parenteral preparations 0,1386
B03AC01 Dextriferron (P) 2845,5 g 0,1 g 0,0585
B03AC02 Iron sucrose (P) 1587,5 g 0,1 g 0,0327
B03AC06 Iron (III)-hydroxide dextran complex (P) 1070,5 g 0,1 g 0,0220
B03AC80 Ferric derisomaltose (P) 1234 g 0,1 g 0,0254
B03AD Iron in combination with folic acid 2,1762
B03AD02 Ferrous fumarate+ Folic acid (O) 580380 pieces 1 pieces 1,1938
B03AD03 Ferrous sulfate+ Folic acid (O) 477650 pieces 1 pieces 0,9825
B03AE Iron in other combinations
B03AE81 Ferrous gluconate+ Manganese gluconate+ Copper
gluconate (O) 1510400 ml
B03AE82 Ferrous fumarate+ Folic acid+ Ascorbic acid (O) 75940 pieces
B03B VITAMIN B12 AND FOLIC ACID 28,4241
B03BA Vitamin B12 (cyanocobalamin and analogues) 8,2948
B03BA01 Cyanocobalamin (O) 17,15 g 1 mg 0,0353
B03BA01 Cyanocobalamin (P) 78,325 g 0,02 mg 8,0551
B03BA03 Hydroxocobalamin (P) 1,987 g 0,02 mg 0,2043
B03BB Folic acid and derivatives 20,1294
B03BB01 Folic acid (O) 3914,6 g 0,4 mg 20,1294
B03X OTHER ANTIANEMIC PREPARATIONS 0,9546
B03XA Other antianemic preparations 0,9546
B03XA01 Erythropoietin (P) 63663000 U 1000 U 0,1309
B03XA02 Darbepoetin alfa (P) 1,4903 g 0,0045 mg 0,6812
B03XA03 Methoxy polyethylene glycol-epoetin beta (P) 0,2772 g 4 mcg 0,1425
B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B05A BLOOD AND RELATED PRODUCTS
7/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B05AA Blood substitutes and plasma protein fractions
B05AA01 Albumin (P) 950202,5 g
B05AA06 Gelatin (P) 4030000 ml
B05AA83 Gelatin (anhydrous)+ Sodium chloride+ Potassium
chloride+ Magnesium chloride+ Sodium lactate (P) 380000 ml
B05AA86 human plasma protein (P) 491600 ml
B05B I.V. SOLUTIONS
B05BA Solutions for parenteral nutrition
B05BA01 Amino acids (P) 761000 ml
B05BA02 Fat emulsions (P) 144300 ml
B05BA03 Carbohydrates (P) 56765300 ml
B05BA10 Combinations (P) 17935741 ml
B05BB Solutions affecting the electrolyte balance
B05BB01 Electrolytes (P) 301979000 ml
B05BB02 Electrolytes+ Carbohydrates (P) 960000 ml
B05BB81 Sodium chloride+ Glucose (P) 290000 ml
B05BC Solutions producing osmotic diuresis
B05BC01 Mannitol (P) 846000 ml
B05C IRRIGATING SOLUTIONS
B05CX Other irrigating solutions
B05CX10 Combinations (NA) 16000 ml
B05D PERITONEAL DIALYTICS
B05DA Isotonic solutions
B05DA80 Isotonic solutions (P) 6080000 ml
B05DB Hypertonic solutions
B05DB80 hypertonic solutions (P) 127754000 ml
B05DB81
Amino acids+ Sodium chloride+ Calcium chloride
dihydrate+ Magnesium chloride hexahydrate+ Sodium
lactate (P)
370000 ml
B05Z HEMODIALYTICS AND HEMOFILTRATES
B05ZB Hemofiltrates
B05ZB80
Sodium chloride+ Potassium chloride+ Calcium chloride
dihydrate+ Magnesium chloride+ Glucose+ Sodium
hydrogen carbonate (P)
27530000 ml
B05ZB82
Calcium chloride dihydrate+ Magnesium chloride
hexahydrate+ Sodium chloride+ Sodium hydrogen
carbonate+ Potassium chloride+ Disodium phosphate
dihydrate (P)
8990000 ml
B05ZB83
Calcium chloride dihydrate+ Magnesium chloride
hexahydrate+ Glucose+ Lactic acid+ Sodium chloride+
Sodium hydrogen carbonate+ Potassium chloride (P)
200000 ml
B05ZB84
Calcium chloride dihydrate+ Magnesium chloride
hexahydrate+ Lactic acid+ Sodium hydrogen carbonate+
Sodium chloride (P)
150000 ml
B05ZB85 Sodium citrate+ Sodium chloride (P) 25000000 ml
B05ZB86
Magnesium chloride hexahydrate+ Sodium chloride+
Potassium chloride+ Disodium phosphate dihydrate+
Sodium hydrogen carbonate (P)
12120000 ml
B05X I.V. SOLUTION ADDITIVES
B05XA Electrolyte solutions
B05XA01 Potassium chloride (P) 750 g
B05XA01 Potassium chloride (P) 3346400 ml
B05XA02 Sodium hydrogen carbonate (P) 1627500 ml
B05XA03 Sodium chloride (P) 333459600 ml
B05XA05 Magnesium sulfate (P) 417900 ml
B05XA07 Calcium chloride (P) 515600 ml
B05XA14 Sodium glycerophosphate hydrate (P) 146000 ml
B05XA80 Electrolytes (P) 124800 ml
8/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B05XB Amino acids
B05XB01 Arginine (P) 3600 ml
B05XB02 Alanyl glutamine (P) 67000 ml
B05XC Vitamins
B05XC80 Vitamins (P) 8164,32 g
B05XC80 Vitamins (P) 109600 ml
B06 OTHER HEMATOLOGICAL AGENTS 0,0034
B06A OTHER HEMATOLOGICAL AGENTS 0,0034
B06AA Enzymes
B06AA03 Hyaluronidase (P) 135000 U
B06AB Heme products
B06AB01 Hemin (P) 120 ml
B06AC Drugs usedin hereditary angioedema 0,0034
B06AC01 C1-inhibitor, plasma derived (P) 137000 U 1400 U 0,0002
B06AC02 Icatibant (P) 5,34 g 0,03 g 0,0004
B06AC05 Lanadelumab (P) 29,4 g 21,4 mg 0,0028
C CARDIOVASCULAR SYSTEM 471,4739
C01 CARDIAC THERAPY 20,4066
C01A CARDIAC GLYCOSIDES 1,8085
C01AA Digitalis glycosides 1,8085
C01AA05 Digoxin (O) 217,98 g 0,25 mg 1,7934
C01AA05 Digoxin (P) 1,8325 g 0,25 mg 0,0151
C01B ANTIARRHYTHMICS, CLASS I AND III 4,9656
C01BA Antiarrhythmics, class Ia
C01BA13 Hydroquinidine (O) 162 g
C01BB Antiarrhythmics, class Ib 0,0211
C01BB02 Mexiletine (O) 198 g 0,8 g 0,0005
C01BB80 Ethacizine (O) 2000 g 0,2 g 0,0206
C01BC Antiarrhythmics, class Ic 3,3044
C01BC03 Propafenone (O) 446476,5 g 0,3 g 3,0611
C01BC03 Propafenone (P) 548,45 g 0,3 g 0,0038
C01BC04 Flecainide (O) 23248 g 0,2 g 0,2391
C01BC04 Flecainide (P) 41,25 g 0,2 g 0,0004
C01BD Antiarrhythmics, class III 1,6402
C01BD01 Amiodarone (O) 153240 g 0,2 g 1,5760
C01BD01 Amiodarone (P) 5013,75 g 0,2 g 0,0516
C01BD07 Dronedarone (O) 4920 g 0,8 g 0,0126
C01C CARDIAC STIMULANTS EXCL. CARDIAC
GLYCOSIDES 0,6961
C01CA Adrenergic and dopaminergic agents 0,6936
C01CA01 Etilefrine (O) 1,6875 g 0,05 g 0,0001
C01CA02 Isoprenaline (P) 0,732 g 0,09 g <0,0001
C01CA03 Norepinephrine (P) 352,6 g 0,006 g 0,1209
C01CA04 Dopamine (P) 1086 g 0,5 g 0,0045
C01CA06 Phenylephrine (P) 137,7 g 0,004 g 0,0708
C01CA07 Dobutamine (P) 1205 g 0,5 g 0,0050
C01CA17 Midodrine (O) 23,65 g 0,03 g 0,0016
C01CA24 Epinephrine (intraoss, P) 85,58 g 0,5 mg 0,3521
C01CA24 Epinephrine (P) 23,067 g 0,5 mg 0,0949
C01CA26 Ephedrine (P) 1066,5 g 0,05 g 0,0439
C01CE Phosphodiesterase inhibitors 0,0018
C01CE02 Milrinone (P) 43,08 g 0,05 g 0,0018
C01CX Other cardiac stimulants 0,0007
C01CX08 Levosimendan (P) 3,725 g 11 mg 0,0007
C01CX80 Ammonia (I) 1467400 ml
C01D VASODILATORS USED IN CARDIAC DISEASES 5,1316
C01DA Organic nitrates 5,1266
C01DA02 Glyceryl trinitrate (P) 183,8 g
C01DA02 Glyceryl trinitrate (SL) 443,552 g 0,0025 g 0,3649
C01DA08 Isosorbide dinitrate (O) 16 g 0,06 g 0,0005
C01DA08 Isosorbide dinitrate (SL) 186,9625 g 0,02 g 0,0192
9/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C01DA14 Isosorbide mononitrate (O) 92217 g 0,04 g 4,7419
C01DX Other vasodilatators used in cardiac diseases 0,0050
C01DX22 Vericiguat (O) 9,275 g 10 mg 0,0019
C01DX80 Meldonium (O) 1080 g 0,75 g 0,0030
C01DX80 Meldonium (P) 45 g 0,75 g 0,0001
C01E OTHER CARDIAC PREPARATIONS 7,8048
C01EA Prostaglandins 0,0002
C01EA01 Alprostadil (P) 0,0528 g 0,5 mg 0,0002
C01EB Other cardiac preparations 7,8045
C01EB10 Adenosine (P) 134,236 g 0,015 g 0,0184
C01EB15 Trimetazidine (O) 141180,9 g 0,04 g 7,2597
C01EB16 Ibuprofen (P) 0,84 g 0,03 g 0,0001
C01EB17 Ivabradine (O) 1973,72 g 0,01 g 0,4060
C01EB18 Ranolazine (O) 87022,5 g 1,5 g 0,1193
C01EB21 Regadenoson (P) 0,21 g 0,4 mg 0,0011
C01EB80 Hawthorn berries (O) 57600 ml
C02 ANTIHYPERTENSIVES 3,7688
C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING 2,3610
C02AC Imidazoline receptor agonists 2,3610
C02AC01 Clonidine (O) 5,19 g 0,45 mg 0,0237
C02AC01 Clonidine (P) 2,191 g 0,45 mg 0,0100
C02AC02 Guanfacine (O) 10,892 g 3 mg 0,0075
C02AC05 Moxonidine (O) 338,3454 g 0,3 mg 2,3198
C02C ANTIADRENERGIC AGENTS, PERIPHERALLY
ACTING 1,3641
C02CA Alpha-adrenoreceptor antagonists 1,3641
C02CA01 Prazosin (O) 0,48 g 0,005 g 0,0002
C02CA04 Doxazosin (O) 2652,492 g 0,004 g 1,3639
C02D ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING
ON 0,0013
C02DD Nitroferricyanide derivatives 0,0013
C02DD01 Sodium nitroprusside (P) 32 g 0,05 g 0,0013
C02K OTHER ANTIHYPERTENSIVES 0,0424
C02KX Antihypertensives for pulmonary arterial hypertension 0,0424
C02KX01 Bosentan (O) 1617 g 0,25 g 0,0133
C02KX02 Ambrisentan (O) 45,45 g 7,5 mg 0,0125
C02KX04 Macitentan (O) 17,1 g 10 mg 0,0035
C02KX05 Riociguat (O) 28,686 g 4,5 mg 0,0131
C03 DIURETICS 26,7824
C03A LOW-CEILING DIURETICS, THIAZIDES 1,0887
C03AA Thiazides, plain 1,0887
C03AA03 Hydrochlorothiazide (O) 13232 g 0,025 g 1,0887
C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES 2,0716
C03BA Sulfonamides, plain 2,0716
C03BA11 Indapamide (O) 2517,87 g 2,5 mg 2,0716
C03C HIGH-CEILING DIURETICS 19,7813
C03CA Sulfonamides, plain 19,7813
C03CA01 Furosemide (O) 57214,6 g 0,04 g 2,9420
C03CA01 Furosemide (P) 5362,6 g 0,04 g 0,2758
C03CA04 Torasemide (O) 120451,65 g 0,015 g 16,5167
C03CA04 Torasemide (P) 341 g 0,015 g 0,0468
C03D ALDOSTERONE ANTAGONISTS AND OTHER
POTASSIUM-SPARING AGENTS 3,8316
C03DA Aldosterone antagonists 3,8300
C03DA01 Spironolactone (O) 139332,75 g 0,075 g 3,8212
C03DA04 Eplerenone (O) 214,5 g 0,05 g 0,0088
C03DB Other potassium-sparing agents 0,0016
C03DB01 Amiloride (O) 7,96 g 10 mg 0,0016
C03E DIURETICS AND POTASSIUM-SPARING AGENTS IN
COMBINATION 0,0093
10/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C03EA Low-ceiling diuretics and potassium-sparing agents 0,0093
C03EA81 Hydrochlorothiazide+ Amiloride (O) 4530 pieces 1 pieces 0,0093
C04 PERIPHERAL VASODILATORS 2,5208
C04A PERIPHERAL VASODILATORS 2,5208
C04AC Nicotinic acid and derivatives 0,0001
C04AC01 Nicotinic acid (P) 5 g 0,2 g 0,0001
C04AD Purine derivatives 1,3867
C04AD02 Xantinol nicotinate (O) 18 g 0,9 g <0,0001
C04AD03 Pentoxifylline (O) 673088 g 1 g 1,3844
C04AD03 Pentoxifylline (P) 320,5 g 0,3 g 0,0022
C04AX Other peripheral vasodilators 1,1341
C04AX21 Naftidrofuryl (O) 330830 g 0,6 g 1,1341
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND
ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA82 Hydrocortisone+ Cinchocaine (R) 11940 pieces
C05AA84 Fluocortolone+ Lidocaine (R) 197175 g
C05AA84 Fluocortolone+ Lidocaine (R) 241850 pieces
C05AE Muscle relaxants
C05AE01 Glyceryl trinitrate (R) 150 g
C05AX Other agents for treatment of hemorrhoids and anal
fissures for topical use
C05AX81 Xeroformium+ Zinc sulphate+ Belladonna extract (R) 1930 pieces
C05AX83 Yeast extract+ Shark-liver oil (R) 279504 pieces
C05B ANTIVARICOSE THERAPY
C05BA Heparins or heparinoids for topical use
C05BA03 Heparin sodium (C) 7213550 g
C05BB Sclerosing agents for local injection
C05BB02 Lauromacrogol 400 (P) 91,8 g
C05C CAPILLARY STABILIZING AGENTS
C05CA Bioflavonoids
C05CA01 Rutoside (O) 272115 pieces
C05CA03 Diosmin (O) 475890 g
C05CA04 Troxerutin (C) 3637200 g
C05CA04 Troxerutin (O) 198885 g
C05CA53 Diosmin+ Hesperidin (O) 618930 pieces
C07 BETA BLOCKING AGENTS 58,5134
C07A BETA BLOCKING AGENTS 58,5127
C07AA Beta blocking agents, non-selective 1,5825
C07AA05 Propranolol (O) 56299 g 0,16 g 0,7237
C07AA07 Sotalol (O) 66800 g 0,16 g 0,8587
C07AB Beta blocking agents, selective 56,3160
C07AB02 Metoprolol (O) 2046374,6 g 0,15 g 28,0606
C07AB02 Metoprolol (P) 113,05 g 0,15 g 0,0016
C07AB03 Atenolol (O) 14983,5 g 0,075 g 0,4109
C07AB07 Bisoprolol (O) 21413,65 g 0,01 g 4,4045
C07AB09 Esmolol (P) 10 g 2,5 g <0,0001
C07AB12 Nebivolol (O) 56976,51 g 0,005 g 23,4384
C07AG Alpha and beta blocking agents 0,6142
C07AG01 Labetalol (O) 32105 g 0,6 g 0,1101
C07AG01 Labetalol (P) 1364,5 g 0,6 g 0,0047
C07AG02 Carvedilol (O) 9106,6875 g 0,0375 g 0,4995
C07B BETA BLOCKING AGENTS AND THIAZIDES 0,0007
C07BB Beta blocking agents, selective, and thiazides 0,0007
C07BB81 Bisoprolol+ Hydrochlorothiazide (O) 360 pieces 1 pieces 0,0007
C08 CALCIUM CHANNEL BLOCKERS 43,0355
C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH
MAINLY VASCULAR EFFECTS 41,6952
11/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C08CA Dihydropyridine derivatives 41,6952
C08CA01 Amlodipine (O) 62736,3 g 0,005 g 25,8078
C08CA02 Felodipine (O) 4549,725 g 0,005 g 1,8716
C08CA05 Nifedipine (O) 11833 g 0,03 g 0,8113
C08CA06 Nimodipine (O) 450 g 0,3 g 0,0031
C08CA06 Nimodipine (P) 0,98 g 0,05 g <0,0001
C08CA08 Nitrendipine (O) 36134,3 g 0,02 g 3,7161
C08CA09 Lacidipine (O) 4599,392 g 0,004 g 2,3651
C08CA13 Lercanidipine (O) 34616,7 g 0,01 g 7,1201
C08D SELECTIVE CALCIUM CHANNEL BLOCKERS WITH
DIRECT CARDIAC EFFECTS 1,3402
C08DA Phenylalkylamine derivatives 1,2019
C08DA01 Verapamil (O) 140242 g 0,24 g 1,2019
C08DA01 Verapamil (P) 4,775 g 0,24 g <0,0001
C08DB Benzothiazepine derivatives 0,1383
C08DB01 Diltiazem (O) 16137 g 0,24 g 0,1383
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN
SYSTEM 213,9459
C09A ACE INHIBITORS, PLAIN 74,6606
C09AA ACE inhibitors, plain 74,6606
C09AA01 Captopril (O) 2,5 g 0,05 g 0,0001
C09AA02 Enalapril (O) 31966,21 g 0,01 g 6,5750
C09AA02 Enalapril (P) 9,9125 g 0,01 g 0,0020
C09AA03 Lisinopril (O) 2,24 g 0,01 g 0,0005
C09AA04 Perindopril (O) 20142,33 g 0,004 g 10,3574
C09AA05 Ramipril (O) 65743,26 g 2,5 mg 54,0896
C09AA09 Fosinopril (O) 25796,96 g 0,015 g 3,5374
C09AA10 Trandolapril (O) 95,816 g 0,002 g 0,0985
C09B ACE INHIBITORS, COMBINATIONS 59,6075
C09BA ACE inhibitors and diuretics 28,4169
C09BA02 Enalapril+ Hydrochlorothiazide (O) 2273684 pieces 1 pieces 4,6766
C09BA04 Perindopril+ Indapamide (O) 10032510 pieces 1 pieces 20,6354
C09BA05 Ramipril+ Hydrochlorothiazide (O) 1030652 pieces 1 pieces 2,1199
C09BA06 Quinapril+ Hydrochlorothiazide (O) 100 pieces 1 pieces 0,0002
C09BA09 Fosinopril+ Hydrochlorothiazide (O) 478790 pieces 1 pieces 0,9848
C09BB ACE inhibitors and calcium channel blockers 13,5294
C09BB03 Lisinopril+ Amlodipine (O) 738570 pieces 1 pieces 1,5191
C09BB04 Perindopril+ Amlodipine (O) 4938660 pieces 1 pieces 10,1581
C09BB07 Ramipril+ Amlodipine (O) 671520 pieces 1 pieces 1,3812
C09BB10 Trandolapril+ Verapamil (O) 228956 pieces 1 pieces 0,4709
C09BX ACE inhibitors, other combinations 17,6612
C09BX01 Perindopril+ Amlodipine+ Indapamide (O) 8586510 pieces 1 pieces 17,6612
C09C ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS),
PLAIN 44,5999
C09CA Angiotensin II receptor blockers (ARBs), plain 44,5999
C09CA01 Losartan (O) 82226 g 0,05 g 3,3825
C09CA02 Eprosartan (O) 428,4 g 0,6 g 0,0015
C09CA03 Valsartan (O) 168660,8 g 0,08 g 4,3364
C09CA06 Candesartan (O) 43007,36 g 0,008 g 11,0575
C09CA07 Telmisartan (O) 430595,2 g 0,04 g 22,1418
C09CA08 Olmesartan medoxomil (O) 35785,96 g 0,02 g 3,6803
C09D ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS),
COMBINATIONS 35,0780
C09DA Angiotensin II receptor blockers (ARBs) and diuretics 14,7274
C09DA80 Losartan+ Hydrochlorothiazide (O) 766910 pieces 1 pieces 1,5774
C09DA82 Valsartan+ Hydrochlorothiazide (O) 858256 pieces 1 pieces 1,7653
C09DA84 Candesartan+ Hydrochlorothiazide (O) 1143214 pieces 1 pieces 2,3514
C09DA85 Telmisartan+ Hydrochlorothiazide (O) 4088276 pieces 1 pieces 8,4090
C09DA86 Olmesartan medoxomil+ Hydrochlorothiazide (O) 303510 pieces 1 pieces 0,6243
12/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C09DB Angiotensin II receptor blockers (ARBs) and calcium
channel blockers 14,3702
C09DB01 Valsartan+ Amlodipine (O) 248708 pieces 1 pieces 0,5116
C09DB02 Olmesartan medoxomil+ Amlodipine (O) 3382120 pieces 1 pieces 6,9565
C09DB04 Telmisartan+ Amlodipine (O) 3285912 pieces 1 pieces 6,7586
C09DB07 Candesartan+ Amlodipine (O) 69776 pieces 1 pieces 0,1435
C09DX Angiotensin II receptor blockers (ARBs), other
combinations 5,9803
C09DX01 Valsartan+ Amlodipine+ Hydrochlorothiazide (O) 4900 pieces 1 pieces 0,0101
C09DX03 Olmesartan medoxomil+ Amlodipine+
Hydrochlorothiazide (O) 2446584 pieces 1 pieces 5,0323
C09DX04 Valsartan+ Sacubitril (O) 456036 pieces 1 pieces 0,9380
C10 LIPID MODIFYING AGENTS 102,5003
C10A LIPID MODIFYING AGENTS, PLAIN 97,8034
C10AA HMG CoA reductase inhibitors 96,0396
C10AA01 Simvastatin (O) 57078,8 g 0,03 g 3,9134
C10AA03 Pravastatin (O) 3542,4 g 0,03 g 0,2429
C10AA04 Fluvastatin (O) 13496 g 0,06 g 0,4627
C10AA05 Atorvastatin (O) 378967,5 g 0,02 g 38,9740
C10AA07 Rosuvastatin (O) 254984,95 g 0,01 g 52,4466
C10AB Fibrates 0,7583
C10AB02 Bezafibrate (O) 20 g 0,6 g 0,0001
C10AB05 Fenofibrate (O) 73728 g 0,2 g 0,7582
C10AC Bile acid sequestrants 0,0029
C10AC01 Colestyramine (O) 19600 g 14 g 0,0029
C10AX Other lipid modifying agents 1,0027
C10AX09 Ezetimibe (O) 4601,04 g 0,01 g 0,9464
C10AX13 Evolocumab (P) 172,2 g 10 mg 0,0354
C10AX14 Alirocumab (P) 17,55 g 5,4 mg 0,0067
C10AX16 Inclisiran (P) 11,076 g 1,6 mg 0,0142
C10AX80 Omega-3-acid ethyl esters 90 (O) 220276 pieces
C10B LIPID MODIFYING AGENTS, COMBINATIONS 4,6969
C10BA Combinations of various lipid modifying agents 3,9577
C10BA05 Atorvastatin+ Ezetimibe (O) 198690 pieces 1 pieces 0,4087
C10BA06 Rosuvastatin+ Ezetimibe (O) 1725450 pieces 1 pieces 3,5490
C10BX Lipid modifying agents in combination with other drugs 0,7392
C10BX11 Atorvastatin+ Amlodipine+ Perindopril (O) 203790 pieces 1 pieces 0,4192
C10BX13 Rosuvastatin+ Perindopril+ Indapamide (O) 139170 pieces 1 pieces 0,2863
C10BX15 Atorvastatin+ Perindopril (O) 16440 pieces 1 pieces 0,0338
D DERMATOLOGICALS 1,8433
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE 1,0176
D01A ANTIFUNGALS FOR TOPICAL USE
D01AC Imidazole and triazole derivatives
D01AC01 Clotrimazole (C) 100 ml
D01AC01 Clotrimazole (C) 1021990 g
D01AC05 Isoconazole (C) 276240 g
D01AC08 Ketoconazole (C) 559545 g
D01AC08 Ketoconazole (C) 2699160 ml
D01AC80 Isoconazole+ Diflucortolone (C) 793875 g
D01AC81 Clotrimazole+ Hexamidine (C) 128790 g
D01AE Other antifungals for topical use
D01AE14 Ciclopirox (C) 630,3 ml
D01AE15 Terbinafine (C) 57849 ml
D01AE15 Terbinafine (C) 494104 g
D01AE16 Amorolfine (C) 26380 ml
D01AE22 Naftifine (C) 141350 ml
D01AE22 Naftifine (C) 205380 g
D01B ANTIFUNGALS FOR SYSTEMIC USE 1,0176
D01BA Antifungals for systemic use 1,0176
D01BA01 Griseofulvin (O) 372,5 g 0,5 g 0,0015
13/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D01BA02 Terbinafine (O) 123493 g 0,25 g 1,0160
D02 EMOLLIENTS AND PROTECTIVES
D02A EMOLLIENTS AND PROTECTIVES
D02AB Zinc products
D02AB80 Zinc oxide (C) 240 g
D02B PROTECTIVES AGAINST UV-RADIATION
D02BA Protectives against UV-radiation for topical use
D02BA01 4-aminobenzoic acid (O) 360 g
D03 PREPARATIONS FOR TREATMENT OF WOUNDS AND
ULCERS
D03A CICATRIZANTS
D03AX Other cicatrizants
D03AX03 Dexpanthenol (C) 4025870 g
D03AX81 Heparin sodium+ Allantoin+ Extractum Cepae (C) 130500 g
D03AX83 Dexpanthenol+ Chlorhexidine (C) 2213190 g
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES,
ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES,
ANESTHETICS, ETC.
D04AA Antihistamines for topical use
D04AA13 Dimetindene (C) 37,74 g
D05 ANTIPSORIATICS 0,0540
D05A ANTIPSORIATICS FOR TOPICAL USE
D05AA Tars
D05AA85 Coal tar+ Salicylic acid (C) 794000 ml
D05AX Other antipsoriatics for topical use
D05AX80 Calcipotriol+ Betamethasone (C) 1064700 g
D05B ANTIPSORIATICS FOR SYSTEMIC USE 0,0540
D05BB Retinoids for treatment of psoriasis 0,0540
D05BB02 Acitretin (O) 919,2 g 0,035 g 0,0540
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR
DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE
D06AX Other antibiotics for topical use
D06AX01 Fusidic acid (C) 243465 g
D06AX09 Mupirocin (C) 2520 g
D06AX80 Bacitracin+ Neomycin (C) 83970 g
D06AX84 Chloramphenicol+ Methyluracil (C) 800 g
D06B CHEMOTHERAPEUTICS FOR TOPICAL USE
D06BA Sulfonamides
D06BA01 Sulfadiazine silver (C) 1466760 g
D06BB Antivirals
D06BB03 Aciclovir (C) 207002 g
D06BB04 Podophyllotoxin (C) 1638 ml
D06BB10 Imiquimod (C) 5679 g
D06BB81 Aciclovir+ Hydrocortisone (C) 28420 g
D06BX Other chemotherapeutics
D06BX01 Metronidazole (C) 162010 g
D07 CORTICOSTEROIDS, DERMATOLOGICAL
PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AA Corticosteroids, weak (group I)
D07AA02 Hydrocortisone (C) 608910 g
D07AB Corticosteroids, moderately potent (group II)
D07AB09 Triamcinolone (C) 355 g
D07AC Corticosteroids, potent (group III)
D07AC01 Betamethasone (C) 114600 g
D07AC04 Fluocinolone acetonide (C) 210 g
D07AC13 Mometasone (C) 332160 ml
D07AC13 Mometasone (C) 1201835 g
D07AC14 Methylprednisolone aceponate (C) 594265 g
14/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D07AC17 Fluticasone (C) 38415 g
D07AD Corticosteroids, very potent (group IV)
D07AD01 Clobetasol (C) 88400 ml
D07AD01 Clobetasol (C) 953175 g
D07B CORTICOSTEROIDS, COMBINATIONS WITH
ANTISEPTICS
D07BA Corticosteroids, weak, combinations with antiseptics
D07BA80 Hydrocortisone+ Chlorhexidine (C) 342860 g
D07BC Corticosteroids, potent, combinations with antiseptics
D07BC80 Betamethasone+ Salicylic acid (C) 26270 g
D07BC80 Betamethasone+ Salicylic acid (C) 977530 ml
D07C CORTICOSTEROIDS, COMBINATIONS WITH
ANTIBIOTICS
D07CA Corticosteroids, weak, combinations with antibiotics
D07CA83 Hydrocortisone+ Fusidic acid (C) 85050 g
D07CC Corticosteroids, potent, combinations with antibiotics
D07CC80 Betamethasone+ Fusidic acid (C) 597240 g
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XA Corticosteroids, weak, other combinations
D07XA81 Prednisolone+ Salicylic acid (C) 252700 ml
D08 ANTISEPTICS AND DISINFECTANTS
D08A ANTISEPTICS AND DISINFECTANTS
D08AG Iodine products
D08AG02 Povidone, iodinated (C) 1172310 ml
D08AG02 Povidone, iodinated (C) 3907170 g
D08AG03 Iodine (C) 1166820 ml
D08AJ Quaternary ammonium compounds
D08AJ81 Octenidine+ Phenoxyethanol (C) 12072850 ml
D08AX Other antiseptics and disinfectants
D08AX82 Tar blend+ Castor oil+ Xeroformium (C) 9730 g
D08AX83 Brilliant Green (C) 289230 ml
D10 ANTI-ACNE PREPARATIONS 0,5991
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AD Retinoids for topical use in acne
D10AD01 Tretinoin (C) 55290 g
D10AD03 Adapalene (C) 78180 g
D10AD80 Adapalene+ Benzoyl peroxide (C) 64170 g
D10AD81 Tretinoin+ Erythromycin (C) 42240 g
D10AF Antiinfectives for treatment of acne
D10AF01 Clindamycin (C) 33300 ml
D10AF02 Erythromycin (C) 368000 ml
D10AF81 Clindamycin+ Benzoyl peroxide (C) 211215 g
D10AF82 Clindamycin+ Tretinoin (C) 139560 g
D10AX Other anti-acne preparations for topical use
D10AX03 Azelaic acid (C) 340920 g
D10B ANTI-ACNE PREPARATIONS FOR SYSTEMIC USE 0,5991
D10BA Retinoids for treatment of acne 0,5991
D10BA01 Isotretinoin (O) 8738,1 g 0,03 g 0,5991
D11 OTHER DERMATOLOGICAL PREPARATIONS 0,1726
D11A OTHER DERMATOLOGICAL PREPARATIONS 0,1726
D11AF Wart and anti-corn preparations
D11AF80 Salicylic acid+ Lactic acid (C) 89070 ml
D11AH Agents for dermatitis, excluding corticosteroids 0,0720
D11AH01 Tacrolimus (C) 119010 g
D11AH02 Pimecrolimus (C) 250275 g
D11AH05 Dupilumab (P) 748,6 g 21,4 mg 0,0720
D11AX Other dermatologicals 0,1007
15/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D11AX01 Minoxidil (C) 158160 ml
D11AX10 Finasteride (O) 48,944 g 0,001 g 0,1007
D11AX16 Eflornithine (C) 390 g
D11AX21 Brimonidine (C) 30 g
D11AX22 Ivermectin (C) 28650 g
G GENITO URINARY SYSTEM AND SEX HORMONES 58,2519
G01 GYNECOLOGICAL ANTIINFECTIVES AND
ANTISEPTICS 0,8455
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL.
COMBINATIONS WITH CORTICOSTEROIDS 0,8455
G01AA Antibiotics 0,0231
G01AA10 Clindamycin (V) 1123,5 g 0,1 g 0,0231
G01AA80 Nystatin+ Neomycin+ Polymyxin B (V) 12 pieces
G01AC Quinoline derivatives 0,0533
G01AC05 Dequalinium (V) 517,8 g 20 mg 0,0533
G01AF Imidazole derivatives 0,7692
G01AF01 Metronidazole (V) 14338 g 0,5 g 0,0590
G01AF02 Clotrimazole (V) 28079,7 g 0,1 g 0,5776
G01AF05 Econazole (V) 4839,3 g 0,1 g 0,0995
G01AF12 Fenticonazole (V) 1609,8 g 0,1 g 0,0331
G02 OTHER GYNECOLOGICALS 3,9212
G02A UTEROTONICS 0,0925
G02AB Ergot alkaloids 0,0022
G02AB01 Methylergometrine (P) 0,2112 g 0,2 mg 0,0022
G02AD Prostaglandins 0,0903
G02AD02 Dinoprostone (P) 0,08 g
G02AD02 Dinoprostone (V) 1,6123 g 0,5 mg 0,0066
G02AD06 Misoprostol (O) 8,1368 g 0,2 mg 0,0837
G02B CONTRACEPTIVES FOR TOPICAL USE 2,2513
G02BA Intrauterine contraceptives
G02BA03 Levonorgestrel (V) 8881 pieces
G02BB Intravaginal contraceptives 2,2513
G02BB01 Etonogestrel+ Ethinylestradiol (V) 38281 pieces 0,036 pieces 2,1872
G02BB81 Benzalkonium chloride (V) 14688 g
G02BB81 Benzalkonium chloride (V) 31170 pieces 1 pieces 0,0641
G02C OTHER GYNECOLOGICALS 1,5775
G02CA Sympathomimetics, labour repressants
G02CA80 Hexoprenaline (P) 0,0205 g
G02CB Prolactine inhibitors 0,1421
G02CB01 Bromocriptine (O) 264,3 g 0,005 g 0,1087
G02CB03 Cabergoline (O) 8,116 g 0,5 mg 0,0334
G02CX Other gynecologicals 1,4353
G02CX01 Atosiban (P) 1,3125 g 0,165 g <0,0001
G02CX03 Agnus castus fruit (O) 380400 pieces 1 pieces 0,7824
G02CX04 Cimicifugae rhizoma (O) 634860 pieces 2 pieces 0,6529
G03 SEX HORMONES AND MODULATORS OF THE
GENITAL SYSTEM 31,0067
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE 23,5400
G03AA Progestogens and estrogens, fixed combinations 18,1700
G03AA07 Levonorgestrel+ Ethinylestradiol (O) 218596 pieces 1 pieces 0,4496
G03AA09 Desogestrel+ Ethinylestradiol (O) 335538 pieces 0,75 pieces 0,9202
G03AA10 Gestodene+ Ethinylestradiol (O) 1933596 pieces 0,75 pieces 5,3028
G03AA12 Drospirenone+ Ethinylestradiol (O) 1162336 pieces 1 pieces 2,3908
G03AA12 Drospirenone+ Ethinylestradiol (O) 1547847 pieces 0,75 pieces 4,2449
G03AA13 Norelgestromin+ Ethinylestradiol (TD) 85920 pieces 0,107 pieces 1,6516
G03AA14 Nomegestrol+ Estradiol (O) 32368 pieces 1 pieces 0,0666
G03AA15 Chlormadinone+ Ethinylestradiol (O) 141876 pieces 0,75 pieces 0,3891
G03AA16 Dienogest+ Ethinylestradiol (O) 1004353 pieces 0,75 pieces 2,7544
G03AB Progestogens and estrogens, sequential preparations 0,1977
16/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G03AB05 Desogestrel+ Ethinylestradiol (O) 1782 pieces 0,75 pieces 0,0049
G03AB08 Dienogest+ Estradiol valerate (O) 93744 pieces 1 pieces 0,1928
G03AC Progestogens 5,0841
G03AC08 Etonogestrel (P) 63,512 g 68 mcg 1,9211
G03AC09 Desogestrel (O) 1298416 pieces 1 pieces 2,6706
G03AC10 Drospirenone (O) 239372 pieces 1 pieces 0,4924
G03AD Emergency contraceptives 0,0882
G03AD01 Levonorgestrel (O) 62,5815 g 1,5 mg 0,0858
G03AD02 Ulipristal (O) 34,29 g 0,03 g 0,0024
G03B ANDROGENS 0,2661
G03BA 3-oxoandrosten (4) derivatives 0,2661
G03BA03 Testosterone (C) 34,5 g 0,05 g 0,0014
G03BA03 Testosterone (O) 7,2 g 0,12 g 0,0001
G03BA03 Testosterone (P) 2315,25 g 0,018 g 0,2646
G03C ESTROGENS 1,6245
G03CA Natural and semisynthetic estrogens, plain 1,6121
G03CA03 Estradiol (C, V) 6,835 g
G03CA03 Estradiol (O) 863,324 g 2 mg 0,8879
G03CA03 Estradiol (TD) 35,3002 g 1,53 mg 0,0475
G03CA03 Estradiol (TD) 126,056 g 1 mg 0,2593
G03CA03 Estradiol (V) 3,0829 g 0,025 mg 0,2536
G03CA04 Estriol (V) 15,9375 g 0,2 mg 0,1639
G03CA80 Estradiol+ Prednisolone (C) 50025 g
G03CX Other estrogens 0,0123
G03CX01 Tibolone (O) 14,98 g 2,5 mg 0,0123
G03D PROGESTOGENS 2,4532
G03DA Pregnen (4) derivatives 1,6745
G03DA02 Medroxyprogesterone (O) 119,55 g 0,005 g 0,0492
G03DA02 Medroxyprogesterone (P) 211,65 g 0,007 g 0,0622
G03DA04 Progesterone (O) 6720 g 0,3 g 0,0461
G03DA04 Progesterone (P) 497,525 g 0,005 g 0,2047
G03DA04 Progesterone (V) 57423,9 g 0,09 g 1,3124
G03DB Pregnadien derivatives 0,7788
G03DB01 Dydrogesterone (O) 2326,8 g 0,01 g 0,4786
G03DB08 Dienogest (O) 291,872 g 2 mg 0,3002
G03F PROGESTOGENS AND ESTROGENS IN
COMBINATION 2,3092
G03FA Progestogens and estrogens, fixed combinations 1,8060
G03FA01 Norethisterone+ Estradiol (O) 533120 pieces 1 pieces 1,0965
G03FA14 Dydrogesterone+ Estradiol (O) 154784 pieces 1 pieces 0,3184
G03FA17 Drospirenone+ Estradiol (O) 190148 pieces 1 pieces 0,3911
G03FB Progestogens and estrogens, sequential preparations 0,5032
G03FB05 Norethisterone+ Estradiol (O) 171892 pieces 1 pieces 0,3536
G03FB08 Dydrogesterone+ Estradiol (O) 72744 pieces 1 pieces 0,1496
G03G GONADOTROPINS AND OTHER OVULATION
STIMULANTS 0,4647
G03GA Gonadotropins 0,2108
G03GA01 Chorionic gonadotrophin (P) 15000 U 250 U 0,0001
G03GA05 Follitropin alfa (P) 6418125 U 75 U 0,1760
G03GA07 Lutropin alfa (P) 691950 U 75 U 0,0190
G03GA08 Choriogonadotropin alfa (P) 0,9168 g 0,25 mg 0,0075
G03GA10 Follitropin delta (P) 0,005 g 12 mcg 0,0009
G03GA30 Follitropin alfa+ Lutropin alfa (P) 3542 dose 1 dose 0,0073
G03GB Ovulation stimulants, synthetic 0,2539
G03GB02 Clomifene (O) 1111 g 0,009 g 0,2539
G03H ANTIANDROGENS 0,3369
G03HA Antiandrogens, plain 0,0672
G03HA01 Cyproterone (O) 3267,5 g 0,1 g 0,0672
G03HB Antiandrogens and estrogens 0,2697
G03HB01 Cyproterone+ Estrogen (O) 98343 pieces 0,75 pieces 0,2697
17/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G03X OTHER SEX HORMONES AND MODULATORS OF
THE GENITAL SYSTEM 0,0120
G03XB Progesterone receptor modulators 0,0120
G03XB01 Mifepristone (O) 826,2 g 0,6 g 0,0028
G03XB02 Ulipristal (O) 22,4 g 5 mg 0,0092
G04 UROLOGICALS 22,4784
G04B UROLOGICALS 4,2142
G04BD Drugs for urinary frequency and incontinence 2,5239
G04BD04 Oxybutynin (O) 4618,5 g 0,015 g 0,6333
G04BD07 Tolterodine (O) 708,904 g 0,004 g 0,3645
G04BD08 Solifenacin (O) 1174,95 g 0,005 g 0,4833
G04BD09 Trospium chloride (O) 3778,65 g 0,04 g 0,1943
G04BD12 Mirabegron (O) 20625 g 50 mg 0,8485
G04BE Drugs used in erectile dysfunction 1,6776
G04BE01 Alprostadil (P) 0,0594 g 0,02 mg 0,0061
G04BE01 Alprostadil (urethral) 0,09 g 0,25 mg 0,0007
G04BE03 Sildenafil (O) 26706,2 g 0,05 g 1,0986
G04BE08 Tadalafil (O) 2460,52 g 0,01 g 0,5061
G04BE09 Vardenafil (O) 75,6 g 0,01 g 0,0155
G04BE10 Avanafil (O) 2452,8 g 0,1 g 0,0505
G04BX Other urologicals 0,0127
G04BX14 Dapoxetine (O) 185,04 g 0,03 g 0,0127
G04BX15 Pentosan polysulfate sodium (O) 9 g 0,3 g 0,0001
G04BX80 Centaurii herba+ Lovage root+ Rosemary leaf (O) 1221900 pieces
G04C DRUGS USED IN BENIGN PROSTATIC
HYPERTROPHY 18,2642
G04CA Alpha-adrenoreceptor antagonists 15,6044
G04CA01 Alfuzosin (O) 8485,8 g 7,5 mg 2,3272
G04CA02 Tamsulosin (O) 1738,3 g 0,4 mg 8,9386
G04CA04 Silodosin (O) 919,56 g 8 mg 0,2364
G04CA52 Tamsulosin+ Dutasteride (O) 1994400 pieces 1 pieces 4,1022
G04CB Testosterone-5-alpha reductase inhibitors 0,5603
G04CB01 Finasteride (O) 473,39 g 0,005 g 0,1947
G04CB02 Dutasteride (O) 88,86 g 0,5 mg 0,3655
G04CX Other drugs used in benign prostatic hypertrophy 2,0995
G04CX02 Sabalis serrulatae fructus (O) 326640 g 0,32 g 2,0995
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX
HORMONES AND INSULINS 32,7553
H01 PITUITARY AND HYPOTHALAMIC HORMONES AND
ANALOGUES 0,4774
H01A ANTERIOR PITUITARY LOBE HORMONES AND
ANALOGUES 0,1800
H01AA ACTH 0,0002
H01AA02 Tetracosactide (P) 0,0293 g 0,25 mg 0,0002
H01AB Thyrotropin 0,0004
H01AB01 Thyrotropin alfa (P) 0,1746 g 0,9 mg 0,0004
H01AC Somatropin and somatropin agonists 0,1586
H01AC01 Somatropin (P) 154200 U 2 U 0,1586
H01AX Other anterior pituitary lobe hormones and analogues 0,0208
H01AX01 Pegvisomant (P) 101,1 g 0,01 g 0,0208
H01B POSTERIOR PITUITARY LOBE HORMONES 0,1624
H01BA Vasopressin and analogues 0,1203
H01BA01 Argipressin (P) 46800 U 40 U 0,0024
H01BA02 Desmopressin (N) 0,03 g 0,025 mg 0,0025
H01BA02 Desmopressin (P) 0,0273 g 0,004 mg 0,0140
H01BA02 Desmopressin (SL) 11,835 g 0,24 mg 0,1014
H01BB Oxytocin and analogues 0,0421
H01BB01 Demoxytocin (O) 768500 U 100 U 0,0158
H01BB02 Oxytocin (P) 167600 U 15 U 0,0230
H01BB03 Carbetocin (P) 0,1608 g 0,1 mg 0,0033
18/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
H01C HYPOTHALAMIC HORMONES 0,1350
H01CA Gonadotropin-releasing hormones
H01CA01 Gonadorelin (P) 0,0038 g
H01CB Somatostatin and analogues 0,1133
H01CB02 Octreotide (P) 7,9285 g 0,7 mg 0,0233
H01CB03 Lanreotide (P) 117,48 g 3 mg 0,0805
H01CB05 Pasireotide (P) 5,5 g 1,2 mg 0,0094
H01CC Anti-gonadotropin-releasing hormones 0,0217
H01CC01 Ganirelix (P) 0,025 g 0,25 mg 0,0002
H01CC02 Cetrorelix (P) 2,615 g 0,25 mg 0,0215
H02 CORTICOSTEROIDS FOR SYSTEMIC USE 8,9653
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN 8,9616
H02AA Mineralocorticoids 0,1623
H02AA02 Fludrocortisone (O) 7,89 g 0,1 mg 0,1623
H02AB Glucocorticoids 8,7993
H02AB01 Betamethasone (P) 13,698 g 1,5 mg 0,0188
H02AB02 Dexamethasone (Infilt, P) 111 g 1,5 mg 0,1522
H02AB02 Dexamethasone (O) 1073,525 g 1,5 mg 1,4721
H02AB02 Dexamethasone (P) 822,7 g 1,5 mg 1,1281
H02AB04 Methylprednisolone (O) 6894 g 7,5 mg 1,8907
H02AB04 Methylprednisolone (P) 4152,55 g 0,02 g 0,4271
H02AB06 Prednisolone (O) 12558,8 g 0,01 g 2,5832
H02AB06 Prednisolone (P) 1607,725 g 0,01 g 0,3307
H02AB08 Triamcinolone (O) 13,6 g 7,5 mg 0,0037
H02AB08 Triamcinolone (P) 1620,6 g 7,5 mg 0,4444
H02AB09 Hydrocortisone (O) 4279,05 g 0,03 g 0,2934
H02AB09 Hydrocortisone (P) 748,4 g 0,03 g 0,0513
H02AB13 Deflazacort (O) 27 g 15 mg 0,0037
H02B CORTICOSTEROIDS FOR SYSTEMIC USE,
COMBINATIONS 0,0037
H02BX Corticosteroids for systemic use, combinations 0,0037
H02BX80 Hydrocortisone+ Lidocaine (P) 53,75 g 0,03 g 0,0037
H03 THYROID THERAPY 23,2668
H03A THYROID PREPARATIONS 22,0325
H03AA Thyroid hormones 22,0325
H03AA01 Levothyroxine sodium (O) 1606,685 g 0,15 mg 22,0314
H03AA02 Liothyronine (O) 0,032 g 0,06 mg 0,0011
H03AA03 Levothyroxine sodium+ Liothyronine (O) 300 pieces
H03AA04 Tiratricol (O) 0,378 g
H03B ANTITHYROID PREPARATIONS 1,2343
H03BA Thiouracils 0,1081
H03BA02 Propylthiouracil (O) 5255,5 g 0,1 g 0,1081
H03BB Sulfur-containing imidazole derivatives 1,1262
H03BB02 Thiamazole (O) 5475,5 g 0,01 g 1,1262
H03BC Perchlorates
H03BC01 Sodium perchlorate (O) 48 g
H04 PANCREATIC HORMONES 0,0008
H04A GLYCOGENOLYTIC HORMONES 0,0008
H04AA Glycogenolytic hormones 0,0008
H04AA01 Glucagon (P) 0,392 g 0,001 g 0,0008
H05 CALCIUM HOMEOSTASIS 0,0450
H05A PARATHYROID HORMONES AND ANALOGUES 0,0002
H05AA Parathyroid hormones and analogues 0,0002
H05AA02 Teriparatide (P) 0,0024 g 0,02 mg 0,0002
H05B ANTI-PARATHYROID AGENTS 0,0447
H05BX Other anti-parathyroid agents 0,0447
H05BX01 Cinacalcet (O) 1304,52 g 0,06 g 0,0447
J ANTIINFECTIVES FOR SYSTEMIC USE 20,6664
J01 ANTIBACTERIALS FOR SYSTEMIC USE 12,3842
J01A TETRACYCLINES 1,5468
J01AA Tetracyclines 1,5468
19/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J01AA02 Doxycycline (O) 75149 g 0,1 g 1,5457
J01AA02 Doxycycline (P) 6 g 0,1 g 0,0001
J01AA08 Minocycline (O) 9 g 0,2 g 0,0001
J01AA12 Tigecycline (P) 41 g 0,1 g 0,0008
J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS 4,8793
J01CA Penicillins with extended spectrum 1,6448
J01CA01 Ampicillin (P) 29800 g 6 g 0,0102
J01CA04 Amoxicillin (O) 1192045 g 1,5 g 1,6346
J01CA04 Amoxicillin (P) 50 g 3 g <0,0001
J01CE Beta-lactamase sensitive penicillins 0,1502
J01CE01 Benzylpenicillin (P) 32280 g 3,6 g 0,0184
J01CE02 Phenoxymethylpenicillin (O) 127347,6 g 2 g 0,1310
J01CE08 Benzathine benzylpenicillin (P) 1360,8 g 3,6 g 0,0008
J01CE80 Benzathine benzylpenicillin+ Benzylpenicillin procaine (P) 25,2 g 3,6 g <0,0001
J01CF Beta-lactamase resistant penicillins 0,0953
J01CF04 Oxacillin (P) 92650 g 2 g 0,0953
J01CR Combinations of penicillins, incl. beta-lactamase
inhibitors 2,9890
J01CR01 Ampicillin+ Sulbactam (P) 74251 g 6 g 0,0255
J01CR02 Amoxicillin+ Clavulanic acid (O) 1914772,15 g 1,5 g 2,6256
J01CR02 Amoxicillin+ Clavulanic acid (P) 347910 g 3 g 0,2385
J01CR04 Sultamicillin (O) 30582 g 1,5 g 0,0419
J01CR05 Piperacillin+ Tazobactam (P) 391160 g 14 g 0,0575
J01D OTHER BETA-LACTAM ANTIBACTERIALS 1,6711
J01DB First-generation cephalosporins 0,2261
J01DB04 Cefazolin (P) 116990 g 3 g 0,0802
J01DB05 Cefadroxil (O) 141903 g 2 g 0,1459
J01DC Second-generation cephalosporins 1,2753
J01DC01 Cefoxitin (P) 11686 g 6 g 0,0040
J01DC02 Cefuroxime (O) 262062 g 0,5 g 1,0780
J01DC02 Cefuroxime (P) 201457,5 g 3 g 0,1381
J01DC10 Cefprozil (O) 26781 g 1 g 0,0551
J01DD Third-generation cephalosporins 0,0688
J01DD01 Cefotaxime (P) 59600 g 4 g 0,0306
J01DD02 Ceftazidime (P) 14076 g 4 g 0,0072
J01DD04 Ceftriaxone (P) 27920 g 2 g 0,0287
J01DD81 Ceftazidime+ Avibactam (P) 6400 g 6 g 0,0022
J01DE Fourth-generation cephalosporins 0,0137
J01DE01 Cefepime (P) 26620 g 4 g 0,0137
J01DH Carbapenems 0,0872
J01DH02 Meropenem (P) 70183 g 3 g 0,0481
J01DH03 Ertapenem (P) 11915 g 1 g 0,0245
J01DH51 Imipenem+ Cilastatin (P) 14175 g 2 g 0,0146
J01DI Other cephalosporins and penems <0,0001
J01DI04 Cefiderocol (P) 20 g
J01DI54 Ceftolozane+ Tazobactam (P) 50 g 3 g <0,0001
J01E SULFONAMIDES AND TRIMETHOPRIM 0,4248
J01EA Trimethoprim and derivatives 0,0302
J01EA01 Trimethoprim (O) 5865 g 0,4 g 0,0302
J01EE Combinations of sulfonamides and trimethoprim, incl.
derivatives 0,3946
J01EE01 Sulfamethoxazole+ Trimethoprim (O) 840 pieces 4 pieces 0,0004
J01EE01 Sulfamethoxazole+ Trimethoprim (O) 342994 pieces 2 pieces 0,3527
J01EE01 Sulfamethoxazole+ Trimethoprim (O) 697000 ml 40 ml 0,0358
J01EE01 Sulfamethoxazole+ Trimethoprim (P) 54480 ml 20 ml 0,0056
J01F MACROLIDES, LINCOSAMIDES AND
STREPTOGRAMINS 2,4338
J01FA Macrolides 2,2306
J01FA01 Erythromycin (P) 800 g 1 g 0,0016
J01FA09 Clarithromycin (O) 384798,5 g 0,5 g 1,5829
20/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J01FA09 Clarithromycin (P) 1731 g 1 g 0,0036
J01FA10 Azithromycin (O) 93703,7 g 0,3 g 0,6424
J01FF Lincosamides 0,2032
J01FF01 Clindamycin (O) 111566,4 g 1,2 g 0,1912
J01FF01 Clindamycin (P) 10491 g 1,8 g 0,0120
J01G AMINOGLYCOSIDE ANTIBACTERIALS 0,0240
J01GB Other aminoglycosides 0,0240
J01GB01 Tobramycin (I) 119,168 g 0,112 g 0,0022
J01GB01 Tobramycin (I) 638,4 g 0,3 g 0,0044
J01GB01 Tobramycin (P) 68 g 0,24 g 0,0006
J01GB03 Gentamicin (P) 1254,925 g 0,24 g 0,0108
J01GB06 Amikacin (P) 2940 g 1 g 0,0060
J01M QUINOLONE ANTIBACTERIALS 0,7185
J01MA Fluoroquinolones 0,7185
J01MA01 Ofloxacin (O) 3356 g 0,4 g 0,0173
J01MA02 Ciprofloxacin (O) 255802,5 g 1 g 0,5261
J01MA02 Ciprofloxacin (P) 10582 g 0,8 g 0,0272
J01MA06 Norfloxacin (O) 39080 g 0,8 g 0,1005
J01MA12 Levofloxacin (O) 4620 g 0,5 g 0,0190
J01MA12 Levofloxacin (P) 323 g 0,5 g 0,0013
J01MA14 Moxifloxacin (O) 4998 g 0,4 g 0,0257
J01MA14 Moxifloxacin (P) 266,4 g 0,4 g 0,0014
J01X OTHER ANTIBACTERIALS 0,6859
J01XA Glycopeptide antibacterials 0,0262
J01XA01 Vancomycin (O) 75 g 2 g 0,0001
J01XA01 Vancomycin (P) 25295 g 2 g 0,0260
J01XA02 Teicoplanin (P) 24 g 0,4 g 0,0001
J01XB Polymyxins 0,0034
J01XB01 Colistin (I) 7600000000 U 9000000 U 0,0017
J01XB01 Colistin (P) 7220000000 U 9000000 U 0,0017
J01XD Imidazole derivatives 0,0352
J01XD01 Metronidazole (P) 25670 g 1,5 g 0,0352
J01XE Nitrofuran derivatives 0,5999
J01XE01 Nitrofurantoin (O) 58328 g 0,2 g 0,5999
J01XX Other antibacterials 0,0213
J01XX01 Fosfomycin (O) 8091 g 3 g 0,0055
J01XX05 Methenamine (O) 300 g
J01XX08 Linezolid (O) 5898 g 1,2 g 0,0101
J01XX08 Linezolid (P) 2661 g 1,2 g 0,0046
J01XX09 Daptomycin (P) 145,05 g 0,28 g 0,0011
J02 ANTIMYCOTICS FOR SYSTEMIC USE 0,3944
J02A ANTIMYCOTICS FOR SYSTEMIC USE 0,3944
J02AA Antibiotics 0,0119
J02AA01 Amphotericin (O) 285 g
J02AA01 Amphotericin (P) 202,4 g 0,035 g 0,0119
J02AB Imidazole derivatives 0,0012
J02AB02 Ketoconazole (O) 120 g 0,2 g 0,0012
J02AC Triazole and tetrazole derivatives 0,3710
J02AC01 Fluconazole (O) 16895,15 g 0,2 g 0,1738
J02AC01 Fluconazole (P) 4049,2 g 0,2 g 0,0416
J02AC02 Itraconazole (O) 11741 g 0,2 g 0,1207
J02AC03 Voriconazole (O) 1873,2 g 0,4 g 0,0096
J02AC03 Voriconazole (P) 343,4 g 0,4 g 0,0018
J02AC04 Posaconazole (O) 3206,4 g 0,3 g 0,0220
J02AC05 Isavuconazole (O) 117,6 g 0,2 g 0,0012
J02AC05 Isavuconazole (P) 29,8 g 0,2 g 0,0003
J02AX Other antimycotics for systemic use 0,0103
J02AX04 Caspofungin (P) 65,18 g 0,05 g 0,0027
J02AX05 Micafungin (P) 1 g 0,1 g <0,0001
J02AX06 Anidulafungin (P) 367,4 g 0,1 g 0,0076
J04 ANTIMYCOBACTERIALS 0,3004
21/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J04A DRUGS FOR TREATMENT OF TUBERCULOSIS 0,2844
J04AB Antibiotics 0,0412
J04AB01 Cycloserine (O) 4500 g 0,75 g 0,0123
J04AB02 Rifampicin (O) 3699,6 g 0,6 g 0,0127
J04AB02 Rifampicin (P) 207 g 0,6 g 0,0007
J04AB05 Rifapentine (O) 828 g 0,11 g 0,0155
J04AC Hydrazides 0,1882
J04AC01 Isoniazid (O) 27450 g 0,3 g 0,1882
J04AD Thiocarbamide derivatives 0,0041
J04AD01 Protionamide (O) 1500 g 0,75 g 0,0041
J04AK Other drugs for treatment of tuberculosis 0,0190
J04AK05 Bedaquiline (O) 639,2 g 86 mg 0,0153
J04AK06 Delamanid (O) 362,4 g 0,2 g 0,0037
J04AK08 Pretomanid (O) 218,4 g
J04AM Combinations of drugs for treatment of tuberculosis 0,0319
J04AM02 Rifampicin+ Isoniazid (O) 10000 pieces 4 pieces 0,0051
J04AM02 Rifampicin+ Isoniazid (O) 26000 pieces 2 pieces 0,0267
J04B DRUGS FOR TREATMENT OF LEPRA 0,0159
J04BA Drugs for treatment of lepra 0,0159
J04BA02 Dapsone (O) 387,5 g 0,05 g 0,0159
J05 ANTIVIRALS FOR SYSTEMIC USE 7,5875
J05A DIRECT ACTING ANTIVIRALS 7,5875
J05AB Nucleosides and nucleotides excl. reverse transcriptase
inhibitors 0,4901
J05AB01 Aciclovir (O) 455492,5 g 4 g 0,2342
J05AB01 Aciclovir (P) 4171,25 g 4 g 0,0021
J05AB06 Ganciclovir (P) 551 g 0,5 g 0,0023
J05AB09 Famciclovir (O) 84 g 0,75 g 0,0002
J05AB11 Valaciclovir (O) 298088 g 3 g 0,2044
J05AB12 Cidofovir (P) 16,5 g 0,025 g 0,0014
J05AB14 Valganciclovir (O) 6344 g 0,9 g 0,0145
J05AB16 Remdesivir (P) 1509,6 g 0,1 g 0,0311
J05AD Phosphonic acid derivatives 0,0009
J05AD01 Foscarnet sodium (P) 2694 g 6,5 g 0,0009
J05AE Protease inhibitors 0,5651
J05AE03 Ritonavir (O) 35733 g 1,2 g 0,0612
J05AE10 Darunavir (O) 293928 g 1,2 g 0,5038
J05AE30 Nirmatrelvir+ Ritonavir (O) 1080 pieces
J05AF Nucleoside and nucleotide reverse transcriptase
inhibitors 0,1463
J05AF01 Zidovudine (O) 430 g 0,6 g 0,0015
J05AF01 Zidovudine (P) 6 g 0,6 g <0,0001
J05AF05 Lamivudine (O) 1542 g 0,3 g 0,0106
J05AF06 Abacavir (O) 1963,2 g 0,6 g 0,0067
J05AF07 Tenofovir disoproxil (O) 404,25 g 0,245 g 0,0034
J05AF10 Entecavir (O) 28,455 g 0,5 mg 0,1171
J05AF13 Tenofovir alafenamide (O) 86,25 g 25 mg 0,0071
J05AG Non-nucleoside reverse transcriptase inhibitors 0,7490
J05AG05 Rilpivirine (O) 9104,25 g 25 mg 0,7490
J05AH Neuraminidase inhibitors 0,2602
J05AH01 Zanamivir (P) 12 g 1,2 g <0,0001
J05AH02 Oseltamivir (O) 18970,5 g 0,15 g 0,2601
J05AJ Integrase inhibitors 1,6100
J05AJ01 Raltegravir (O) 586368 g 0,8 g 1,5076
J05AJ03 Dolutegravir (O) 2489,85 g 50 mg 0,1024
J05AP Antivirals for treatment of HCV infections 0,1333
J05AP01 Ribavirin (O) 16,8 g 1 g <0,0001
J05AP54 Elbasvir+ Grazoprevir (O) 10388 pieces 1 pieces 0,0214
J05AP55 Sofosbuvir+ Velpatasvir (O) 6300 pieces 1 pieces 0,0130
J05AP57 Glecaprevir+ Pibrentasvir (O) 144256 pieces 3 pieces 0,0989
22/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J05AR Antivirals for treatment of HIV infections, combinations 3,6326
J05AR02 Lamivudine+ Abacavir (O) 181680 pieces 1 pieces 0,3737
J05AR03 Tenofovir disoproxil+ Emtricitabine (O) 1120410 pieces 1 pieces 2,3045
J05AR06 Emtricitabine+ Tenofovir disoproxil+ Efavirenz (O) 152850 pieces 1 pieces 0,3144
J05AR10 Lopinavir+ Ritonavir (O) 15840 g 0,8 g 0,0407
J05AR13 Lamivudine+ Abacavir+ Dolutegravir (O) 128040 pieces 1 pieces 0,2634
J05AR18 Emtricitabine+ Tenofovir alafenamide+ Elvitegravir+
Cobicistat (O) 480 pieces 1 pieces 0,0010
J05AR25 Lamivudine+ Dolutegravir (O) 162840 pieces 1 pieces 0,3349
J05AX Other antivirals
J05AX10 Maribavir (O) 48 g
J06 IMMUNE SERA AND IMMUNOGLOBULINS
J06A IMMUNE SERA
J06AA Immune sera
J06AA01 Diphtheria antitoxin (P) 20 pieces
J06AA03 Snake venom antiserum (P) 76 pieces
J06B IMMUNOGLOBULINS
J06BA Immunoglobulins, normal human
J06BA01 Immunoglobulins, normal human, for extravascular a (P) 12326,1 g
J06BA02 Immunoglobulins, normal human, for intravascular a (P) 125407,5 g
J06BB Specific immunoglobulins
J06BB01 Human Anti-D Immunoglobulin (P) 1791875 U
J06BB02 Tetanus immunoglobulins (P) 6000 U
J06BB03 Varicella-zoster immune globulin (P) 1250 U
J06BB04 Hepatitis B immunoglobulins (P) 1000 U
J06BB05 Rabies immunoglobulin (P) 1500 U
J06BB09 Cytomegalovirus immunoglobulin (P) 120000 U
J06BD Antiviral monoclonal antibodies
J06BD01 Palivizumab (P) 32,3 g
J06BD03 Tixagevimab+ Cilgavimab (P) 1296 ml
J06BD06 Regdanvimab (P) 76,8 g
J07 VACCINES
J07A BACTERIAL VACCINES
J07AG Hemophilus influenzae B vaccines
J07AG01 Haemophilus influenzae B, purified antigen conjugated
(P) 273 dose
J07AH Meningococcal vaccines
J07AH08 Meningococcus, tetravalent purified polysaccharides
antigen conjugated (P) 203 dose
J07AH09 Meningococcus B, multicomponent vaccine (P) 118 dose
J07AL Pneumococcal vaccines
J07AL01 Pneumococcus, purified polysaccharides antigen (P) 500 dose
J07AL02 Pneumococcus, purified polysaccharides antigen
conjugated (P) 2658 dose
J07AL52 Pneumococcus, purified polysaccharides antigen+
Haemophilus influenzae, conjugated (P) 226 dose
J07AM Tetanus vaccines
J07AM51 Tetanus toxoid+ Diphtheria toxoid (P) 81976 dose
J07AN Tuberculosis vaccines
J07AN01 Tuberculosis, live attenuated (P) 1771 dose
J07AP Typhoid vaccines
J07AP03 Typhoid, purified polysaccharide antigen (P) 850 dose
J07AX Other bacterial vaccines
J07AX80 Diphtheria-tetanus-pertussis (P) 18080 dose
J07B VIRAL VACCINES
J07BA Encephalitis vaccines
J07BA01 Encephalitis, tick borne, inactivated, whole virus (P) 72595 dose
23/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J07BB Influenza vaccines
J07BB02 Influenza, inactivated, split virus or surface antigen (P) 191263 dose
J07BB03 Influenza vaccine (live attenuated, nasal) (N) 1890 dose
J07BC Hepatitis vaccines
J07BC01 Hepatitis B, purified antigen (P) 4851 dose
J07BC02 Hepatitis A, inactivated, whole virus (P) 2627 dose
J07BC80 Hepatitis A, inactivated, whole virus+ Hepatitis B, purified
antigen (P) 1294 dose
J07BD Measles vaccines
J07BD52 Measles virus (live, attenuated)+ Rubella virus (live,
attenuated)+ Mumps virus (live, attenuated) (P) 35869 dose
J07BF Poliomyelitis vaccines
J07BF03 Poliomyelitis, trivalent, inactivated, whole virus (P) 712 dose
J07BG Rabies vaccines
J07BG01 Rabies, inactivated, whole virus (P) 1706 dose
J07BH Rota virus diarrhea vaccines
J07BH02 Rota virus, pentavalent, live, reassorted (O) 39281 dose
J07BK Varicella zoster vaccines
J07BK01 Varicella, live attenuated (P) 2283 dose
J07BK02 Zoster, live attenuated (P) 88 dose
J07BK03 Zoster, purified antigen (P) 8 dose
J07BL Yellow fever vaccines
J07BL01 Yellow fever virus live, attenuated (P) 1249 dose
J07BM Papillomavirus vaccines
J07BM02 Human papillomavirus vaccine (types 16, 18)
recombinant, adjuvanted, adsorbed (P) 3 dose
J07BM03 Human papillomavirus vaccine (types 6, 11, 16, 18, 31,
33, 45, 52, 58) (P) 13833 dose
J07BN Covid-19 vaccines
J07BN01 Covid-19, RNA-based vaccine (P) 78980 dose
J07BN01 Covid-19, RNA-based vaccine (P) 434224,269 dose
J07BN02 Covid-19, viral vector, non-replicating (P) 17600 dose
J07BN04 Covid-19, protein subunit (P) 29070 dose
J07BX Other viral vaccines
J07BX01 Smallpox vaccine (P) 600 dose
J07C BACTERIAL AND VIRAL VACCINES, COMBINED
J07CA Bacterial and viral vaccines, combined
J07CA02
Diphtheria toxoid+ Pertussis, purified antigen+ Tetanus
toxoid+ Poliomyelitis, trivalent, inactivated, whole virus
(P)
13355 dose
J07CA06
Diphtheria toxoid+ Tetanus toxoid+ Pertussis, purified
antigen+ Poliomyelitis, trivalent, inactivated, whole virus+
Haemophilus influenzae B, purified antigen conjugated
(P)
642 dose
J07CA09
Diphtheria toxoid+ Poliomyelitis, trivalent, inactivated,
whole virus+ Pertussis, purified antigen+ Haemophilus
influenzae B, purified antigen conjugated+ Hepatitis B,
purified antigen+ Tetanus toxoid (P)
60158 dose
L ANTINEOPLASTIC AND IMMUNOMODULATING
AGENTS 13,9703
L01 ANTINEOPLASTIC AGENTS 0,5300
L01A ALKYLATING AGENTS
L01AA Nitrogen mustard analogues
L01AA01 Cyclophosphamide (O) 390 g
L01AA01 Cyclophosphamide (P) 3315 g
L01AA02 Chlorambucil (O) 11,55 g
L01AA03 Melphalan (O) 2,45 g
L01AA03 Melphalan (P) 15,5 g
24/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01AA06 Ifosfamide (P) 1984,5 g
L01AA07 Trofosfamide (O) 10 g
L01AA09 Bendamustine (P) 97,5 g
L01AB Alkyl sulfonates
L01AB01 Busulfan (O) 5,6 g
L01AB01 Busulfan (P) 1,44 g
L01AB02 Treosulfan (P) 600 g
L01AC Ethylene imines
L01AC01 Thiotepa (P) 3,745 g
L01AD Nitrosoureas
L01AD01 Carmustine (P) 9,2 g
L01AD02 Lomustine (O) 22 g
L01AD04 Streptozocin (P) 1 g
L01AX Other alkylating agents
L01AX03 Temozolomide (O) 785,3 g
L01AX04 Dacarbazine (P) 206 g
L01B ANTIMETABOLITES
L01BA Folic acid analogues
L01BA01 Methotrexate (P) 639,7 g
L01BA04 Pemetrexed (P) 464 g
L01BB Purine analogues
L01BB02 Mercaptopurine (O) 292,5 g
L01BB03 Tioguanine (O) 6 g
L01BB04 Cladribine (P) 0,43 g
L01BB05 Fludarabine (P) 16,5 g
L01BB06 Clofarabine (P) 0,5 g
L01BB07 Nelarabine (P) 21 g
L01BC Pyrimidine analogues
L01BC01 Cytarabine (P) 1609 g
L01BC02 Fluorouracil (C) 60 g
L01BC02 Fluorouracil (P) 13723 g
L01BC05 Gemcitabine (P) 6133,88 g
L01BC06 Capecitabine (O) 270435 g
L01BC07 Azacitidine (P) 438,1 g
L01BC82 Fluorouracil+ Salicylic acid (C) 300 ml
L01BC83 Trifluridine+ Tipiracil (O) 19240 pieces
L01C PLANT ALKALOIDS AND OTHER NATURAL
PRODUCTS
L01CA Vinca alkaloids and analogues
L01CA01 Vinblastine (P) 1,94 g
L01CA02 Vincristine (P) 2,021 g
L01CA04 Vinorelbine (O) 0,64 g
L01CA04 Vinorelbine (P) 18,45 g
L01CB Podophyllotoxin derivatives
L01CB01 Etoposide (O) 233 g
L01CB01 Etoposide (P) 466 g
L01CD Taxanes
L01CD01 Paclitaxel (P) 997,4 g
L01CD02 Docetaxel (P) 457,28 g
L01CD04 Cabazitaxel (P) 2,64 g
L01CE Topoisomerase 1 (TOP1) inhibitors
L01CE01 Topotecan (P) 2,02 g
L01CE02 Irinotecan (P) 700 g
L01CX Other plant alkaloids and natural products
L01CX01 Trabectedin (P) 0,0125 g
L01D CYTOTOXIC ANTIBIOTICS AND RELATED
SUBSTANCES
L01DA Actinomycines
L01DA01 Dactinomycin (P) 0,0665 g
L01DB Anthracyclines and related substances
L01DB01 Doxorubicin (P) 117,7 g
25/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01DB02 Daunorubicin (P) 14,38 g
L01DB03 Epirubicin (P) 188,5 g
L01DB06 Idarubicin (O) 0,08 g
L01DB06 Idarubicin (P) 0,35 g
L01DB07 Mitoxantrone (P) 1,44 g
L01DB11 Pixantrone (P) 1,276 g
L01DC Other cytotoxic antibiotics
L01DC01 Bleomycin (P) 6000000 U
L01DC03 Mitomycin (P) 3,54 g
L01E PROTEIN KINASE INHIBITORS 0,5300
L01EA BCR-ABL tyrosine kinase inhibitors 0,1336
L01EA01 Imatinib (O) 15972 g 0,4 g 0,0821
L01EA02 Dasatinib (O) 612 g 0,1 g 0,0126
L01EA03 Nilotinib (O) 10080 g 0,6 g 0,0346
L01EA04 Bosutinib (O) 453,6 g 0,4 g 0,0023
L01EA05 Ponatinib (O) 43,2 g 45 mg 0,0020
L01EB Epidermal growth factor receptor (EGFR) tyrosine kinase
inhibitors 0,0227
L01EB01 Gefitinib (O) 1387,5 g 0,25 g 0,0114
L01EB02 Erlotinib (O) 24 g 0,15 g 0,0003
L01EB03 Afatinib (O) 89,04 g 40 mg 0,0046
L01EB04 Osimertinib (O) 249,6 g 80 mg 0,0064
L01EB10 Mobocertinib (O) 14,4 g
L01EC B-Raf serine-threonine kinase (BRAF) inhibitors 0,0186
L01EC02 Dabrafenib (O) 2709 g 0,3 g 0,0186
L01ED Anaplastic lymphoma kinase (ALK) inhibitors 0,0120
L01ED01 Crizotinib (O) 30 g 0,5 g 0,0001
L01ED02 Ceritinib (O) 247,5 g 0,45 g 0,0011
L01ED03 Alectinib (O) 2083,2 g 1,2 g 0,0036
L01ED04 Brigatinib (O) 627,48 g 0,18 g 0,0072
L01EE Mitogen-activated protein kinase (MEK) inhibitors 0,0200
L01EE01 Trametinib (O) 19,425 g 2 mg 0,0200
L01EE03 Binimetinib (O) 2,52 g 90 mg 0,0001
L01EE04 selumetinib (O) 19,2 g
L01EF Cyclin-dependent kinase (CDK) inhibitors 0,1021
L01EF01 Palbociclib (O) 3719,625 g 94 mg 0,0814
L01EF02 Ribociclib (O) 4536 g 0,45 g 0,0207
L01EG Mammalian target of rapamycin (mTOR) kinase
inhibitors 0,0097
L01EG01 Temsirolimus (P) 2,28 g 3,57 mg 0,0013
L01EG02 Everolimus (O) 40,8 g 10 mg 0,0084
L01EJ Janus-associated kinase (JAK) inhibitors 0,0201
L01EJ01 Ruxolitinib (C) 0,9 g
L01EJ01 Ruxolitinib (O) 292,6 g 30 mg 0,0201
L01EK Vascular endothelial growth factor receptor (VEGFR)
tyrosine kinase inhibitors 0,0017
L01EK01 Axitinib (O) 8,288 g 10 mg 0,0017
L01EL Bruton's tyrosine kinase (BTK) inhibitors 0,0548
L01EL01 Ibrutinib (O) 10122 g 0,42 g 0,0496
L01EL02 Acalabrutinib (O) 510 g 0,2 g 0,0052
L01EX Other protein kinase inhibitors 0,1346
L01EX01 Sunitinib (O) 457,45 g 33 mg 0,0285
L01EX02 Sorafenib (O) 2710,4 g 0,8 g 0,0070
L01EX03 Pazopanib (O) 11658 g 0,8 g 0,0300
L01EX04 Vandetanib (O) 27 g 0,3 g 0,0002
L01EX05 regorafenib (O) 164,64 g 0,12 g 0,0028
L01EX07 Cabozantinib (O) 499,24 g 60 mg 0,0171
L01EX08 Lenvatinib (O) 82,74 g 18 mg 0,0095
L01EX09 Nintedanib (O) 6825 g 0,38 g 0,0369
L01EX10 Midostaurin (O) 114,8 g 0,1 g 0,0024
L01EX14 Entrectinib (O) 90 g 0,6 g 0,0003
26/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01F MONOCLONAL ANTIBODIES AND ANTIBODY DRUG
CONJUGATES
L01FA CD20 (Clusters of Differentiation 20) inhibitors
L01FA01 Rituximab (P) 1830,28 g
L01FA03 Obinutuzumab (P) 136 g
L01FB CD22 (Clusters of Differentiation 22) inhibitors
L01FB01 Inotuzumab ozogamicin (P) 0,012 g
L01FC CD38 (Clusters of Differentiation 38) inhibitors
L01FC01 Daratumumab (P) 1283,4 g
L01FD HER2 (Human Epidermal Growth Factor Receptor 2)
inhibitors
L01FD01 Trastuzumab (P) 1393,95 g
L01FD02 Pertuzumab (P) 90,3 g
L01FD03 Trastuzumab emtansine (P) 155,32 g
L01FD04 Trastuzumab deruxtecan (P) 17,5 g
L01FE EGFR (Epidermal Growth Factor Receptor) inhibitors
L01FE01 Cetuximab (P) 9,8 g
L01FE02 Panitumumab (P) 72,1 g
L01FF PD-1/PDL-1 (Programmed cell death protein 1/death
ligand 1) inhibitors
L01FF01 Nivolumab (P) 408,96 g
L01FF02 Pembrolizumab (P) 441 g
L01FF03 Durvalumab (P) 381 g
L01FF05 Atezolizumab (P) 847,2 g
L01FG VEGF/VEGFR (Vascular Endothelial Growth Factor)
inhibitors
L01FG01 Bevacizumab (P) 1530 g
L01FG02 Ramucirumab (P) 4,3 g
L01FX Other monoclonal antibodies and antibody drug
conjugates
L01FX02 Gemtuzumab ozogamicin (P) 0,005 g
L01FX04 Ipilimumab (P) 1,75 g
L01FX05 Brentuximab vedotin (P) 13,15 g
L01FX06 Dinutuximab beta (P) 0,5063 g
L01FX07 Blinatumomab (P) 0,0015 g
L01FX09 Mogamulizumab (P) 0,32 g
L01FX20 Tremelimumab (P) 0,3 g
L01X OTHER ANTINEOPLASTIC AGENTS
L01XA Platinum compounds
L01XA01 Cisplatin (P) 189,4 g
L01XA02 Carboplatin (P) 2028 g
L01XA03 Oxaliplatin (P) 883,8 g
L01XB Methylhydrazines
L01XB01 Procarbazine (O) 145 g
L01XD Sensitizers used in photodynamic/radiation therapy
L01XD04 Aminolevulinic acid (O) 39 g
L01XF Retinoids for cancer treatment
L01XF01 Tretinoin (O) 101 g
L01XG Proteasome inhibitors
L01XG01 Bortezomib (P) 9,324 g
L01XG02 Carfilzomib (P) 22,51 g
L01XG03 Ixazomib (O) 0,6 g
L01XJ Hedgehog pathway inhibitors
L01XJ01 Vismodegib (O) 25,2 g
L01XK Poly (ADP-ribose) polymerase (PARP) inhibitors
L01XK01 Olaparib (O) 9116,8 g
L01XX Other antineoplastic agents
L01XX01 Amsacrine (P) 1,35 g
L01XX02 Asparaginase (P) 1950000 U
L01XX05 Hydroxycarbamide (O) 265300 g
27/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01XX11 Estramustine (O) 44,8 g
L01XX23 Mitotane (O) 900 g
L01XX24 Pegaspargase (P) 168750 U
L01XX27 Arsenic trioxide (P) 9,86 g
L01XX35 Anagrelide (O) 1,15 g
L01XX41 Eribulin (P) 0,3458 g
L01XX52 Venetoclax (O) 5611,34 g
L01XX73 Sotorasib (O) 172,8 g
L01XX75 Tebentafusp (P) 0,0054 g
L01XY Combinations of antineoplastic agents
L01XY02 Pertuzumab+ Trastuzumab (P) 7330 ml
L02 ENDOCRINE THERAPY 5,0127
L02A HORMONES AND RELATED AGENTS 0,9032
L02AB Progestogens 0,0098
L02AB02 Medroxyprogesterone (O) 4770 g 1 g 0,0098
L02AE Gonadotropin releasing hormone analogues 0,8934
L02AE03 Goserelin (P) 10,8216 g 0,129 mg 0,1725
L02AE04 Triptorelin (P) 0,3738 g 0,1 mg 0,0077
L02AE04 Triptorelin (P) 46,4625 g 0,134 mg 0,7132
L02B HORMONE ANTAGONISTS AND RELATED AGENTS 4,1095
L02BA Anti-estrogens 0,8139
L02BA01 Tamoxifen (O) 6365,4 g 0,02 g 0,6546
L02BA03 Fulvestrant (P) 642,5 g 8,3 mg 0,1592
L02BB Anti-androgens 1,0476
L02BB03 Bicalutamide (O) 23994,6 g 0,05 g 0,9871
L02BB04 enzalutamide
(O) 4341,12 g 0,16 g 0,0558
L02BB05 Apalutamide (O) 144 g 0,24 g 0,0012
L02BB06 Darolutamide (O) 2049,6 g 1,2 g 0,0035
L02BG Aromatase inhibitors 2,1515
L02BG03 Anastrozole (O) 361,92 g 1 mg 0,7444
L02BG04 Letrozole (O) 1558,2 g 2,5 mg 1,2820
L02BG06 Exemestane (O) 1521 g 0,025 g 0,1251
L02BX Other hormone antagonists and related agents 0,0964
L02BX03 Abiraterone (O) 46890 g 1 g 0,0964
L03 IMMUNOSTIMULANTS 0,4213
L03A IMMUNOSTIMULANTS 0,4213
L03AA Colony stimulating factors 0,0884
L03AA02 Filgrastim (P) 10,0323 g 0,35 mg 0,0590
L03AA13 Pegfilgrastim (P) 4,29 g 0,3 mg 0,0294
L03AB Interferons 0,2393
L03AB07 Interferon beta-1a (P) 0,3483 g 0,0043 mg 0,1666
L03AB08 Interferon beta-1b (P) 62760000000 U 4000000 U 0,0323
L03AB11 Peginterferon alfa-2a (P) 0,0567 g 0,026 mg 0,0045
L03AB13 Peginterferon beta-1a (P) 0,1556 g 8,9 mcg 0,0360
L03AX Other immunostimulants 0,0936
L03AX03 BCG bacteria (P) 4,1375 g 1,8 mg 0,0047
L03AX13 Glatiramer acetate (P) 863,52 g 0,02 g 0,0888
L03AX16 Plerixafor (P) 0,432 g 16,8 mg 0,0001
L04 IMMUNOSUPPRESSANTS 8,0064
L04A IMMUNOSUPPRESSANTS 8,0064
L04AA Selective immunosuppressants 1,2610
L04AA03 Anti-T lymphocyte immunoglobulin for human use, horse
(P) 7,5 g
L04AA04 Anti-T lymphocyte immunoglobulin for human use, rabbit
(P) 12,375 g 0,1 g 0,0003
L04AA06 Mycophenolic acid (O) 307761 g 2 g 0,3165
L04AA06 Mycophenolic acid (P) 234 g 2 g 0,0002
L04AA10 Sirolimus (O) 26,58 g 0,003 g 0,0182
L04AA13 Leflunomide (O) 4878,9 g 0,02 g 0,5018
28/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L04AA18 Everolimus (O) 0,36 g 1,5 mg 0,0005
L04AA23 Natalizumab (P) 56,1 g 0,01 g 0,0115
L04AA24 Abatacept (P) 238 g 0,027 g 0,0181
L04AA25 Eculizumab (P) 102,3 g 0,064 g 0,0033
L04AA26 Belimumab (P) 4,8 g 25 mg 0,0004
L04AA27 Fingolimod (O) 3,416 g 0,5 mg 0,0141
L04AA29 Tofacitinib
(O) 143,528 g 10 mg 0,0295
L04AA31 Teriflunomide (O) 747,936 g 14 mg 0,1099
L04AA33 Vedolizumab (P) 93,3 g 5,4 mg 0,0355
L04AA34 Alemtuzumab (P) 0,504 g 0,13 mg 0,0080
L04AA36 Ocrelizumab (P) 130,8 g 3,29 mg 0,0818
L04AA37 Baricitinib
(O) 3,92 g 3 mg 0,0027
L04AA40 Cladribine (O) 2,5 g 0,34 mg 0,0151
L04AA42 Siponimod (O) 40,462 g
L04AA43 ravulizumab (P) 5,2 g 58,9 mg 0,0002
L04AA44 Upadacitinib (O) 447,3 g 15 mg 0,0613
L04AA47 Inebilizumab (P) 1,2 g
L04AA50 Ponesimod (O) 32,274 g 20 mg 0,0033
L04AA52 Ofatumumab (P) 9,38 g 0,67 mg 0,0288
L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors 1,7520
L04AB01 Etanercept (P) 1139,1 g 0,007 g 0,3347
L04AB02 Infliximab (P) 1161,8 g 3,75 mg 0,6372
L04AB04 Adalimumab (P) 965,64 g 2,9 mg 0,6849
L04AB05 Certolizumab pegol (P) 28,8 g 14 mg 0,0042
L04AB06 Golimumab (P) 73,35 g 1,66 mg 0,0909
L04AC Interleukin inhibitors 0,6313
L04AC02 Basiliximab (P) 1,04 g 0,04 g 0,0001
L04AC03 Anakinra (P) 124,5195 g 0,1 g 0,0026
L04AC05 Ustekinumab (P) 85,62 g 0,54 mg 0,3261
L04AC07 Tocilizumab (P) 902,312 g 0,02 g 0,0928
L04AC10 Secukinumab (P) 511,65 g 10 mg 0,1052
L04AC13 Ixekizumab (P) 30,4 g 2,9 mg 0,0216
L04AC14 Sarilumab (P) 136,4 g 14,3 mg 0,0196
L04AC16 Guselkumab (P) 21,2 g 1,79 mg 0,0244
L04AC18 Risankizumab (P) 31,65 g 1,67 mg 0,0390
L04AD Calcineurin inhibitors 0,5096
L04AD01 Ciclosporin (O) 29483,75 g 0,25 g 0,2426
L04AD01 Ciclosporin (P) 57,5 g 0,25 g 0,0005
L04AD02 Tacrolimus (O) 647,6 g 5 mg 0,2664
L04AD02 Tacrolimus (P) 0,3 g 5 mg 0,0001
L04AX Other immunosuppressants 3,8525
L04AX01 Azathioprine (O) 32905 g 0,15 g 0,4512
L04AX02 Thalidomide (O) 177,8 g 0,1 g 0,0037
L04AX03 Methotrexate (O) 3572,95 g 2,5 mg 2,9396
L04AX03 Methotrexate (P) 146,075 g 2,5 mg 0,1202
L04AX04 Lenalidomide (O) 513,66 g 0,01 g 0,1057
L04AX05 Pirfenidone (O) 18570,384 g 2,4 g 0,0159
L04AX06 Pomalidomide
(O) 12,747 g 3 mg 0,0087
L04AX07 Dimethyl fumarate (O) 40375,44 g 0,48 g 0,1730
L04AX09 Diroximel fumarate (O) 15523,2 g 0,924 g 0,0346
M MUSCULO-SKELETAL SYSTEM 91,7225
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC
PRODUCTS 73,1429
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC
PRODUCTS, NON-STEROIDS 73,1321
M01AB Acetic acid derivatives and related substances 8,8031
M01AB01 Indometacin (O) 1553,275 g 0,1 g 0,0319
M01AB05 Diclofenac (O) 286682,25 g 0,1 g 5,8966
29/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
M01AB05 Diclofenac (P) 7467,375 g 0,1 g 0,1536
M01AB05 Diclofenac (R) 11719,375 g 0,1 g 0,2411
M01AB15 Ketorolac (P) 0,3 g 30 mg <0,0001
M01AB16 Aceclofenac (O) 44684 g 0,2 g 0,4595
M01AB82 Diclofenac+ Omeprazole (O) 98221,5 g 0,1 g 2,0203
M01AC Oxicams 3,5788
M01AC01 Piroxicam (O) 989,2 g 0,02 g 0,1017
M01AC05 Lornoxicam (O) 2015,36 g 0,012 g 0,3454
M01AC06 Meloxicam (O) 22681,875 g 0,015 g 3,1102
M01AC06 Meloxicam (P) 156 g 0,015 g 0,0214
M01AE Propionic acid derivatives 43,5330
M01AE01 Ibuprofen (O) 16187635,2 g 1,2 g 27,7463
M01AE01 Ibuprofen (P) 10706 g 1,2 g 0,0184
M01AE02 Naproxen (O) 776690,75 g 0,5 g 3,1951
M01AE03 Ketoprofen (O) 149395,5 g 0,15 g 2,0486
M01AE03 Ketoprofen (P) 11820 g 0,15 g 0,1621
M01AE17 Dexketoprofen (O) 90957 g 0,075 g 2,4945
M01AE17 Dexketoprofen (P) 3687,25 g 0,075 g 0,1011
M01AE52 Naproxen+ Esomeprazole (O) 1887150 g 0,5 g 7,7632
M01AE82 Ibuprofen+ Phenylephrine (O) 2275,2 g 1,2 g 0,0039
M01AG Fenamates 0,0037
M01AG02 Tolfenamic acid (O) 540 g 0,3 g 0,0037
M01AH Coxibs 10,1303
M01AH01 Celecoxib (O) 86967 g 0,2 g 0,8944
M01AH05 Etoricoxib (O) 269417,61 g 60 mg 9,2359
M01AX Other antiinflammatory and antirheumatic agents, non-
steroids 7,0833
M01AX01 Nabumetone (O) 141280 g 1 g 0,2906
M01AX05 Glucosamine (O) 4953734,04 g 1,5 g 6,7927
M01C SPECIFIC ANTIRHEUMATIC AGENTS 0,0108
M01CC Penicillamine and similar agents 0,0108
M01CC01 Penicillamine (O) 2617,5 g 0,5 g 0,0108
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR
PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR
PAIN
M02AA Antiinflammatory preparations, non-steroids for topical
use
M02AA10 Ketoprofen (C) 1202850 g
M02AA12 Naproxen (C) 1081190 g
M02AA13 Ibuprofen (C) 31324 pieces
M02AA13 Ibuprofen (C) 890800 g
M02AA15 Diclofenac (C) 461939 pieces
M02AA15 Diclofenac (C) 32275750 g
M02AA81 Ibuprofen+ Levomenthol (C) 1953800 g
M02AC Preparations with salicylic acid derivatives
M02AC80 Methyl salicylate+ Levomenthol+ Eucalyptus oil+
Turpentine oil (C) 127635 g
M02AX Other topical products for joint and muscular pain
M02AX80 Nicoboxil+ Nonivamide (C) 211100 g
M02AX90 Camphor+ Salicylic acid+ Turpentine oil+ Viperae beri
venenum (C) 996575 g
M02AX92 Benzyl nicotinate+ Nonivamide+ Camphor+ Turpentine
oil+ Dimethyl sulfoxide (C) 752880 g
M03 MUSCLE RELAXANTS 0,9974
M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING
AGENTS
M03AB Choline derivatives
M03AB01 Suxamethonium chloride (P) 3050 g
M03AC Other quaternary ammonium compounds
M03AC03 Vecuronium bromide (P) 0,1 g
30/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
M03AC04 Atracurium besilate (P) 2013,625 g
M03AC06 Pipecuronium bromide (P) 8,7 g
M03AC09 Rocuronium bromide (P) 1244 g
M03AX Other muscle relaxants, peripherally acting agents
M03AX01 Botulinum toxin (P) 2404950 U
M03B MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS 0,9974
M03BX Other centrally acting agents 0,9974
M03BX01 Baclofen (O) 4550,5 g 0,05 g 0,1872
M03BX01 Baclofen (P) 2,0528 g 0,55 mg 0,0077
M03BX02 Tizanidine (O) 4682,04 g 0,012 g 0,8025
M04 ANTIGOUT PREPARATIONS 12,5230
M04A ANTIGOUT PREPARATIONS 12,5230
M04AA Preparations inhibiting uric acid production 12,5032
M04AA01 Allopurinol (O) 1606220 g 0,4 g 8,2594
M04AA03 Febuxostat (O) 165060 g 0,08 g 4,2438
M04AB Preparations increasing uric acid excretion 0,0023
M04AB01 Probenecid (O) 100 g 1 g 0,0002
M04AB03 Benzbromarone (O) 100 g 0,1 g 0,0021
M04AC Preparations with no effect on uric acid metabolism 0,0176
M04AC01 Colchicine (O) 8,555 g 1 mg 0,0176
M05 DRUGS FOR TREATMENT OF BONE DISEASES 5,0512
M05B DRUGS AFFECTING BONE STRUCTURE AND
MINERALIZATION 5,0512
M05BA Bisphosphonates 0,7600
M05BA03 Pamidronic acid (P) 3 g 0,06 g 0,0001
M05BA04 Alendronic acid (O) 259 g 0,01 g 0,0533
M05BA06 Ibandronic acid (O) 1402,2 g 0,005 g 0,5768
M05BA07 Risedronic acid (O) 294,42 g 0,005 g 0,1211
M05BA08 Zoledronic acid (P) 16,978 g 0,004 g 0,0087
M05BB Bisphosphonates, combinations 2,6040
M05BB03 Alendronic acid+ Colecalciferol (O) 12659,92 g 10 mg 2,6040
M05BX Other drugs affecting bone structure and mineralization 1,6872
M05BX04 Denosumab (P) 270,343 g 0,33 mg 1,6850
M05BX05 Burosumab (P) 2,7 g 2,5 mg 0,0022
M05BX07 Vosoritide (P) 0,3472 g
M09 OTHER DRUGS FOR DISORDERS OF THE MUSCULO-
SKELETAL SYSTEM 0,0079
M09A OTHER DRUGS FOR DISORDERS OF THE MUSCULO-
SKELETAL SYSTEM 0,0079
M09AX Other drugs for disorders of the musculo-skeletal system 0,0079
M09AX10 Risdiplam (O) 19,32 g 5 mg 0,0079
N NERVOUS SYSTEM 160,8567
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AB Halogenated hydrocarbons
N01AB06 Isoflurane (I) 5000 ml
N01AB07 Desflurane (I) 84960 ml
N01AB08 Sevoflurane (I) 823250 ml
N01AF Barbiturates, plain
N01AF03 Thiopental (P) 2330 g
N01AH Opioid anesthetics
N01AH01 Fentanyl (I) 0,212 g
N01AH01 Fentanyl (P) 37,561 g
N01AH06 Remifentanil (P) 23,76 g
N01AX Other general anesthetics
N01AX03 Ketamine (P) 1317 g
N01AX07 Etomidate (P) 39,9 g
N01AX10 Propofol (P) 87958,5 g
31/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N01AX13 Nitrous oxide (I) 11696000 ml
N01AX14 Esketamine (P) 442 g
N01B ANESTHETICS, LOCAL
N01BB Amides
N01BB01 Bupivacaine (Infilt, P) 3639,75 g
N01BB01 Bupivacaine (P) 256,1 g
N01BB02 Lidocaine (C) 2730 pieces
N01BB02 Lidocaine (C) 5100 ml
N01BB02 Lidocaine (NA) 5400 ml
N01BB02 Lidocaine (NA) 87026 g
N01BB02 Lidocaine (O) 101760 g
N01BB02 Lidocaine (P) 26036,3 g
N01BB03 Mepivacaine (dental) 1379,55 g
N01BB08 Articaine (P) 2,4 g
N01BB09 Ropivacaine (P) 897,3 g
N01BB80 Articaine+ Epinephrine (dental) 933980 ml
N01BB80 Articaine+ Epinephrine (O) 603360 ml
N01BB81 Bupivacaine+ Epinephrine (P) 260800 ml
N01BB82 Lidocaine+ Epinephrine (dental) 1100 ml
N01BB82 Lidocaine+ Epinephrine (dental, P) 86000 ml
N01BB83 Lidocaine+ Prilocaine (C) 97920 g
N01BB86 Lidocaine+ Chlorhexidine (urethral) 1422562,5 g
N01BC Esters of benzoic acid
N01BC01 Cocaine (NA) 485 g
N01BX Other local anesthetics
N01BX04 Capsaicin (C) 154220 g
N02 ANALGESICS 39,1300
N02A OPIOIDS 10,5817
N02AA Natural opium alkaloids 0,9972
N02AA01 Morphine (O) 4234,5 g 0,1 g 0,0871
N02AA01 Morphine (P) 552,1 g 0,03 g 0,0379
N02AA05 Oxycodone (O) 26376,15 g 0,075 g 0,7234
N02AA05 Oxycodone (P) 425,8 g 0,03 g 0,0292
N02AA08 Dihydrocodeine (O) 7349,4 g 0,15 g 0,1008
N02AA55 Oxycodone+ Naloxone (O) 691,35 g 75 mg 0,0190
N02AB Phenylpiperidine derivatives 0,1495
N02AB02 Pethidine (P) 469,5 g 0,4 g 0,0024
N02AB02 Pethidine (P, V) 1080 g 0,4 g 0,0056
N02AB03 Fentanyl (O) 2,3068 g
N02AB03 Fentanyl (SL) 2,707 g 0,6 mg 0,0093
N02AB03 Fentanyl (TD) 77,1664 g 1,2 mg 0,1323
N02AE Oripavine derivatives 0,0066
N02AE01 Buprenorphine (TD) 3,8674 g 1,2 mg 0,0066
N02AJ Opioids in combination with non-opioid analgesics 7,6803
N02AJ06 Codeine+ Paracetamol (O) 8948960 pieces 3 pieces 6,1356
N02AJ13 Tramadol+ Paracetamol (O) 2101,125 g 150 mg 0,0288
N02AJ14 Tramadol+ Dexketoprofen (O) 110552,625 g 150 mg 1,5159
N02AX Other opioids 1,7480
N02AX02 Tramadol (O) 252166,5 g 0,3 g 1,7289
N02AX02 Tramadol (P) 2784,5 g 0,3 g 0,0191
N02B OTHER ANALGESICS AND ANTIPYRETICS 27,2658
N02BA Salicylic acid and derivatives 0,9654
N02BA01 Acetylsalicylic acid (O) 1179075,84 g 3 g 0,8084
N02BA01 Acetylsalicylic acid (P) 55 g
N02BA80 Acetylsalicylic acid + Ascorbic acid (O) 229061,6 g 3 g 0,1570
N02BB Pyrazolones 0,0013
N02BB02 Metamizole sodium (P) 1940 g 3 g 0,0013
N02BB86 Metamizole sodium+ Pitofenone (O) 45 g
N02BE Anilides 20,4968
N02BE01 Paracetamol (O) 22407489,7 g 3 g 15,3630
N02BE01 Paracetamol (P) 347624 g 3 g 0,2383
32/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N02BE01 Paracetamol (R) 87891,9 g 3 g 0,0603
N02BE52 Paracetamol+ Pseudoephedrine+ Diphenhydramine (O) 1304 g 3 g 0,0009
N02BE70 Paracetamol+ Ibuprofen (O) 55360 g 3 g 0,0380
N02BE75 Paracetamol+ Guaifenesin+ Phenylephrine (O) 455684 g 3 g 0,3124
N02BE81 Paracetamol+ Chlorphenamine+ Pseudoephedrine+
Dextromethorphan (O) 537804 g 3 g 0,3687
N02BE83 Paracetamol+ Caffeine (O) 414744 g 3 g 0,2844
N02BE84 Paracetamol+ Phenylephrine+ Ascorbic acid (O) 1415825 g 3 g 0,9707
N02BE85 Paracetamol+ Pheniramine+ Ascorbic acid (O) 98530,4 g 3 g 0,0676
N02BE86 Paracetamol+ Phenylephrine+ Terpin hydrate+ Ascorbic
acid+ Caffeine (O) 450402 g 3 g 0,3088
N02BE87 Paracetamol+ Pseudoephedrine (O) 44770 g 3 g 0,0307
N02BE91 Paracetamol+ Ascorbic acid (O) 18044,4 g 3 g 0,0124
N02BE92 Paracetamol+ Codeine (O) 1134150 g 3 g 0,7776
N02BE94 Paracetamol+ Codeine+ Caffeine (O) 1748580 g 3 g 1,1989
N02BE95 Paracetamol+ Phenylephrine (O) 40 g 3 g <0,0001
N02BE97 Paracetamol+ Pseudoephedrine+ Dextromethorphan (O) 677188 g 3 g 0,4643
N02BF Gabapentinoids 5,8021
N02BF01 Gabapentin (O) 2055610 g 1,8 g 2,3489
N02BF02 Pregabalin (O) 503661,2 g 0,3 g 3,4532
N02BG Other analgesics and antipyretics 0,0001
N02BG80 Dronabinol+ Cannabidiol (O) 300 dose 8 dose 0,0001
N02C ANTIMIGRAINE PREPARATIONS 1,2825
N02CC Selective serotonin (5HT1) agonists 1,2494
N02CC01 Sumatriptan (N) 0,84 g 0,02 g 0,0001
N02CC01 Sumatriptan (O) 27151,5 g 0,05 g 1,1169
N02CC03 Zolmitriptan (O) 99,07 g 2,5 mg 0,0815
N02CC04 Rizatriptan (O) 58,44 g 0,01 g 0,0120
N02CC07 Frovatriptan (O) 47,2 g 2,5 mg 0,0388
N02CD Calcitonin gene-related peptide (CGRP) antagonists 0,0332
N02CD01 Erenumab (P) 16,24 g 2,5 mg 0,0134
N02CD03 fremanezumab (P) 72,225 g 7,5 mg 0,0198
N02CD05 Eptinezumab (P) 3,6 g
N03 ANTIEPILEPTICS 7,5127
N03A ANTIEPILEPTICS 7,5127
N03AA Barbiturates and derivatives 0,2960
N03AA02 Phenobarbital (O) 12300 g 0,1 g 0,2530
N03AA02 Phenobarbital (P) 30 g 0,1 g 0,0006
N03AA03 Primidone (O) 25750 g 1,25 g 0,0424
N03AB Hydantoin derivatives 0,0350
N03AB02 Phenytoin (O) 4930 g 0,3 g 0,0338
N03AB02 Phenytoin (P) 172,5 g 0,3 g 0,0012
N03AD Succinimide derivatives 0,0212
N03AD01 Ethosuximide (O) 12862,5 g 1,25 g 0,0212
N03AE Benzodiazepine derivatives 0,5550
N03AE01 Clonazepam (O) 2158,8 g 0,008 g 0,5550
N03AF Carboxamide derivatives 2,5368
N03AF01 Carbamazepine (O) 865440 g 1 g 1,7801
N03AF02 Oxcarbazepine (O) 367665 g 1 g 0,7562
N03AF03 Rufinamide (O) 360 g 1,4 g 0,0005
N03AG Fatty acid derivatives 1,7520
N03AG01 Valproic acid (O) 1267405 g 1,5 g 1,7379
N03AG01 Valproic acid (P) 2113,5 g 1,5 g 0,0029
N03AG04 Vigabatrin (O) 10900 g 2 g 0,0112
N03AX Other antiepileptics 2,3167
N03AX03 Sultiame (O) 3680 g 0,4 g 0,0189
N03AX09 Lamotrigine (O) 145105,8 g 0,3 g 0,9949
N03AX11 Topiramate (O) 40999,5 g 0,3 g 0,2811
33/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N03AX14 Levetiracetam (O) 737722,5 g 1,5 g 1,0116
N03AX14 Levetiracetam (P) 1325 g 1,5 g 0,0018
N03AX15 Zonisamide (O) 74,2 g 0,2 g 0,0008
N03AX17 Stiripentol (O) 795 g 1 g 0,0016
N03AX18 Lacosamide (O) 486,5 g 0,3 g 0,0033
N03AX22 perampanel (O) 2,016 g 8 mg 0,0005
N03AX24 Cannabidiol (O) 720 g 0,7 g 0,0021
N04 ANTI-PARKINSON DRUGS 3,7003
N04A ANTICHOLINERGIC AGENTS 0,5605
N04AA Tertiary amines 0,5605
N04AA01 Trihexyphenidyl (O) 2725,2 g 0,01 g 0,5605
N04B DOPAMINERGIC AGENTS 3,1398
N04BA Dopa and dopa derivatives 1,4919
N04BA03 Levodopa + Carbidopa+ Entacapone (O) 69965 g 0,45 g 0,3198
N04BA80 Levodopa + Benserazide (O) 316250 g 0,6 g 1,0841
N04BA81 Levodopa + Carbidopa (intestin) 21462 g
N04BA81 Levodopa + Carbidopa (O) 25648 g 0,6 g 0,0879
N04BB Adamantane derivatives 0,3004
N04BB01 Amantadine (O) 29210 g 0,2 g 0,3004
N04BB01 Amantadine (P) 4 g
N04BC Dopamine agonists 0,7834
N04BC04 Ropinirole (O) 1082,536 g 0,006 g 0,3711
N04BC05 Pramipexole (O) 487,5675 g 2,5 mg 0,4011
N04BC07 Apomorphine (P) 108,65 g 20 mg 0,0112
N04BD Monoamine oxidase type B inhibitors 0,5641
N04BD02 Rasagiline (O) 274,262 g 0,001 g 0,5641
N05 PSYCHOLEPTICS 46,7668
N05A ANTIPSYCHOTICS 10,7098
N05AA Phenothiazines with aliphatic side-chain 0,1335
N05AA01 Chlorpromazine (O) 8368,125 g 0,3 g 0,0574
N05AA01 Chlorpromazine (P) 26 g 0,1 g 0,0005
N05AA02 Levomepromazine (O) 11017 g 0,3 g 0,0755
N05AA02 Levomepromazine (P) 5 g 0,1 g 0,0001
N05AB Phenothiazines with piperazine structure 0,0825
N05AB02 Fluphenazine (P) 3,125 g 0,001 g 0,0064
N05AB03 Perphenazine (O) 408,4 g 0,03 g 0,0280
N05AB03 Perphenazine (P) 233,712 g 0,01 g 0,0481
N05AC Phenothiazines with piperidine structure 0,0005
N05AC01 Periciazine (O) 12 g 0,05 g 0,0005
N05AD Butyrophenone derivatives 0,9394
N05AD01 Haloperidol (O) 1936,465 g 0,008 g 0,4979
N05AD01 Haloperidol (P) 804,8 g 0,008 g 0,2069
N05AD03 Melperone (O) 32950 g 0,3 g 0,2259
N05AD08 Droperidol (P) 10,525 g 2,5 mg 0,0087
N05AE Indole derivatives 0,0717
N05AE03 Sertindole (O) 551,68 g 0,016 g 0,0709
N05AE04 Ziprasidone (O) 31,2 g 0,08 g 0,0008
N05AF Thioxanthene derivatives 0,8345
N05AF01 Flupentixol (O) 358,65 g 0,006 g 0,1229
N05AF01 Flupentixol (P) 121,88 g 0,004 g 0,0627
N05AF03 Chlorprothixene (O) 28042,5 g 0,3 g 0,1923
N05AF05 Zuclopenthixol (O) 1269 g 0,03 g 0,0870
N05AF05 Zuclopenthixol (P) 41,5 g 0,03 g 0,0028
N05AF05 Zuclopenthixol (P) 2674,6 g 0,015 g 0,3668
N05AH Diazepines, oxazepines, thiazepines and oxepines 6,3317
N05AH02 Clozapine (O) 101269 g 0,3 g 0,6943
N05AH03 Olanzapine (O) 12229,42 g 0,01 g 2,5154
N05AH03 Olanzapine (P) 253,07 g 0,01 g 0,0521
N05AH04 Quetiapine (O) 597006 g 0,4 g 3,0699
N05AL Benzamides 0,1188
N05AL01 Sulpiride (O) 18085,5 g 0,8 g 0,0465
34/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N05AL05 Amisulpride (O) 14052 g 0,4 g 0,0723
N05AN Lithium 0,3573
N05AN01 Lithium (O) 156360 g 0,9 g 0,3573
N05AX Other antipsychotics 1,8399
N05AX08 Risperidone (O) 1751,14 g 0,005 g 0,7204
N05AX08 Risperidone (P) 20,6 g 2,7 mg 0,0157
N05AX12 Aripiprazole (O) 5894,34 g 0,015 g 0,8083
N05AX12 Aripiprazole (P) 5,9377 g 0,015 g 0,0008
N05AX12 Aripiprazole (P) 759,2 g 0,0133 g 0,1174
N05AX13 Paliperidone (P) 104,075 g 2,5 mg 0,0856
N05AX15 Cariprazine (O) 133,77 g 3 mg 0,0917
N05B ANXIOLYTICS 13,3017
N05BA Benzodiazepine derivatives 13,3011
N05BA01 Diazepam (O) 27435,75 g 0,01 g 5,6431
N05BA01 Diazepam (P) 460,1 g 0,01 g 0,0946
N05BA01 Diazepam (R) 58,75 g 0,01 g 0,0121
N05BA06 Lorazepam (O) 1187,55 g 2,5 mg 0,9770
N05BA06 Lorazepam (P) 29 g 2,5 mg 0,0239
N05BA08 Bromazepam (O) 5399,58 g 0,01 g 1,1106
N05BA09 Clobazam (O) 465 g 0,02 g 0,0478
N05BA12 Alprazolam (O) 2613,5325 g 0,001 g 5,3756
N05BA80 Phenazepam (O) 7,9 g 0,001 g 0,0162
N05BB Diphenylmethane derivatives 0,0002
N05BB01 Hydroxyzine (O) 8,25 g 0,075 g 0,0002
N05BE Azaspirodecanedione derivatives 0,0004
N05BE01 Buspirone (O) 5,4 g 0,03 g 0,0004
N05C HYPNOTICS AND SEDATIVES 22,7554
N05CD Benzodiazepine derivatives 0,1578
N05CD02 Nitrazepam (O) 162,3 g 0,005 g 0,0668
N05CD08 Midazolam (O) 69,825 g 0,015 g 0,0096
N05CD08 Midazolam (P) 453,9 g 0,015 g 0,0622
N05CD08 Midazolam (P, R) 140,5 g 0,015 g 0,0193
N05CD14 Remimazolam (P) 0,2 g
N05CF Benzodiazepine related drugs 21,3903
N05CF01 Zopiclone (O) 60417,465 g 7,5 mg 16,5693
N05CF02 Zolpidem (O) 23147,87 g 0,01 g 4,7612
N05CF04 Eszopiclone (O) 58,184 g 2 mg 0,0598
N05CH Melatonin receptor agonists 0,7566
N05CH01 Melatonin (O) 735,72 g 2 mg 0,7566
N05CM Other hypnotics and sedatives 0,4506
N05CM09 Valerianae radix (O) 615330 pieces 3 pieces 0,4219
N05CM18 Dexmedetomidine (P) 13,962 g 1 mg 0,0287
N06 PSYCHOANALEPTICS 51,1844
N06A ANTIDEPRESSANTS 44,4687
N06AA Non-selective monoamine reuptake inhibitors 1,9928
N06AA02 Imipramine (O) 18,75 g 0,1 g 0,0004
N06AA04 Clomipramine (O) 4591,65 g 0,1 g 0,0944
N06AA04 Clomipramine (P) 2,5 g 0,1 g 0,0001
N06AA09 Amitriptyline (O) 58676,5 g 0,075 g 1,6092
N06AA10 Nortriptyline (O) 10527,5 g 0,075 g 0,2887
N06AB Selective serotonin reuptake inhibitors 26,2635
N06AB03 Fluoxetine (O) 40737,16 g 0,02 g 4,1895
N06AB04 Citalopram (O) 14242,04 g 0,02 g 1,4647
N06AB05 Paroxetine (O) 23454 g 0,02 g 2,4121
N06AB06 Sertraline (O) 200415,2 g 0,05 g 8,2445
N06AB08 Fluvoxamine (O) 1557,5 g 0,1 g 0,0320
N06AB10 Escitalopram (O) 48232,66 g 0,01 g 9,9207
N06AF Monoamine oxidase inhibitors, non-selective 0,0111
N06AF04 Tranylcypromine (O) 54 g 0,01 g 0,0111
N06AX Other antidepressants 16,2013
N06AX03 Mianserin (O) 27 g 0,06 g 0,0009
35/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N06AX05 Trazodone (O) 30261 g 0,3 g 0,2075
N06AX11 Mirtazapine (O) 42300,45 g 0,03 g 2,9002
N06AX12 Bupropion (O) 194562 g 0,3 g 1,3340
N06AX14 Tianeptine (O) 22557,375 g 0,0375 g 1,2373
N06AX16 Venlafaxine (O) 240438,75 g 0,1 g 4,9455
N06AX18 Reboxetine (O) 1,12 g 0,008 g 0,0003
N06AX21 Duloxetine (O) 89776,92 g 0,06 g 3,0776
N06AX22 Agomelatine (O) 15804,6 g 0,025 g 1,3003
N06AX26 Vortioxetine (O) 5808,6 g 10 mg 1,1947
N06AX27 Esketamine (N) 11,844 g 8 mg 0,0030
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD
AND NOOTROPICS 2,9768
N06BA Centrally acting sympathomimetics 2,6602
N06BA04 Methylphenidate (O) 36732,48 g 0,03 g 2,5184
N06BA07 Modafinil (O) 1299 g 0,3 g 0,0089
N06BA09 Atomoxetine (O) 5165,72 g 0,08 g 0,1328
N06BA12 Lisdexamfetamine dimesylate (O) 1088,1 g
N06BC Xanthine derivatives
N06BC81 Caffeine citrate (O, P) 53 g
N06BC81 Caffeine citrate (P) 2,5 g
N06BX Other psychostimulants and nootropics 0,3166
N06BX03 Piracetam (O) 352896 g 2,4 g 0,3024
N06BX13 Idebenone (O) 270 g 0,9 g 0,0006
N06BX18 Vinpocetine (O) 99 g 15 mg 0,0136
N06BX83 Aminobutyric acid (O) 31010 g
N06D ANTI-DEMENTIA DRUGS 3,7389
N06DA Anticholinesterases 1,3503
N06DA02 Donepezil (O) 4922,4 g 7,5 mg 1,3500
N06DA03 Rivastigmine (O) 1,26 g 0,009 g 0,0003
N06DA04 Galantamine (O) 0,224 g 0,016 g <0,0001
N06DX Other anti-dementia drugs 2,3886
N06DX01 Memantine (O) 6454,04 g 0,02 g 0,6638
N06DX02 Ginkgo folium (O) 100632 g 0,12 g 1,7249
N06DX80 Cerebrolysin (P) 2,152 g
N07 OTHER NERVOUS SYSTEM DRUGS 12,5625
N07A PARASYMPATHOMIMETICS 0,3781
N07AA Anticholinesterases 0,3781
N07AA01 neostigmine (P) 30,455 g 0,002 g 0,0313
N07AA02 Pyridostigmine bromide (O) 27729 g 0,18 g 0,3169
N07AA03 Distigmine bromide (O) 0,2 g 0,005 g 0,0001
N07AA80 Neostigmine+ Glycopyrronium (P) 14510 ml 1 ml 0,0298
N07AX Other parasympathomimetics
N07AX01 Pilocarpine (O) 1,26 g
N07B DRUGS USED IN ADDICTIVE DISORDERS 3,3609
N07BA Drugs used in nicotine dependence 1,7488
N07BA01 Nicotine (O) 16609,69 g 0,03 g 1,1388
N07BA01 Nicotine (TD) 4152,106 g 0,014 g 0,6100
N07BB Drugs used in alcohol dependence 0,4531
N07BB01 Disulfiram (O) 36510 g 0,2 g 0,3755
N07BB01 Disulfiram (P) 136 g
N07BB03 Acamprosate (O) 279,72 g 2 g 0,0003
N07BB04 Naltrexone (O) 1750 g 50 mg 0,0720
N07BB05 nalmefene (O) 46,368 g 18 mg 0,0053
N07BC Drugs used in opioid dependence 1,1590
N07BC02 Methadone (O) 13523 g 0,025 g 1,1126
N07BC51 Buprenorphine+ Naloxone (SL) 180,537 g 8 mg 0,0464
N07C ANTIVERTIGO PREPARATIONS 8,7896
N07CA Antivertigo preparations 8,7896
N07CA01 Betahistine (O) 88644,48 g 0,024 g 7,5970
N07CA02 Cinnarizine (O) 48326,25 g 0,09 g 1,1044
N07CA03 Flunarizine (O) 9 g 0,01 g 0,0019
36/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N07CA80 Cinnarizine+ Dimenhydrinate (O) 3774,88 g 90 mg 0,0863
N07X OTHER NERVOUS SYSTEM DRUGS 0,0339
N07XX Other nervous system drugs 0,0339
N07XX02 Riluzole (O) 1430,8 g 0,1 g 0,0294
N07XX04 Sodium oxybate (O) 180 g 7,5 g <0,0001
N07XX06 Tetrabenazine (O) 182 g 0,1 g 0,0037
N07XX07 Fampridine (O) 6,72 g 20 mg 0,0007
N07XX14 Edaravone (P) 6,9 g
P ANTIPARASITIC PRODUCTS, INSECTICIDES AND
REPELLENTS 1,0614
P01 ANTIPROTOZOALS 0,8513
P01A AGENTS AGAINST AMOEBIASIS AND OTHER
PROTOZOAL DISEASES 0,1870
P01AB Nitroimidazole derivatives 0,1870
P01AB01 Metronidazole (O) 181845 g 2 g 0,1870
P01AB01 Metronidazole (O, V) 261 g
P01AX Other agents against amoebiasis and other protozoal
diseases <0,0001
P01AX11 Nitazoxanide (O) 6 g 1 g <0,0001
P01B ANTIMALARIALS 0,6643
P01BA Aminoquinolines 0,6490
P01BA02 Hydroxychloroquine (O) 162666 g 0,516 g 0,6484
P01BA03 Primaquine (O) 4,5 g 0,015 g 0,0006
P01BB Biguanides 0,0148
P01BB51 Proguanil+ Atovaquone (O) 1008 pieces 16 pieces 0,0001
P01BB51 Proguanil+ Atovaquone (O) 28500 pieces 4 pieces 0,0147
P01BD Diaminopyrimidines 0,0004
P01BD01 Pyrimethamine (O) 13,5 g 0,075 g 0,0004
P01BE Artemisinin and derivatives, plain 0,0001
P01BE03 Artesunate (P) 14,28 g 0,28 g 0,0001
P02 ANTHELMINTICS 0,2101
P02B ANTITREMATODALS 0,0001
P02BA Quinoline derivatives and related substances 0,0001
P02BA01 Praziquantel (O) 187,2 g 3 g 0,0001
P02C ANTINEMATODAL AGENTS 0,2100
P02CA Benzimidazole derivatives 0,2090
P02CA01 Mebendazole (O) 18880,4 g 0,2 g 0,1942
P02CA03 Albendazole (O) 2880 g 0,4 g 0,0148
P02CF Avermectines 0,0010
P02CF01 Ivermectin (O) 5,73 g 12 mg 0,0010
P03 ECTOPARASITICIDES, INCL. SCABICIDES,
INSECTICIDES AND REPELLENTS
P03A ECTOPARASITICIDES, INCL. SCABICIDES
P03AC Pyrethrines, incl. synthetic compounds
P03AC04 Permethrin (C) 311310 g
P03AX Other ectoparasiticides, incl. scabicides
P03AX01 Benzyl benzoate (C) 253650 g
R RESPIRATORY SYSTEM 112,7122
R01 NASAL PREPARATIONS 48,5930
R01A DECONGESTANTS AND OTHER NASAL
PREPARATIONS FOR TOPICAL USE 45,1979
R01AA Sympathomimetics, plain 28,2963
R01AA05 Oxymetazoline (N) 184,6875 g 0,4 mg 0,9497
R01AA07 Xylometazoline (N) 10636,285 g 0,8 mg 27,3466
R01AB Sympathomimetics, combinations excl. corticosteroids 5,5672
R01AB83 Xylometazoline+ Ipratropium bromide (N) 331170 ml 0,8 ml 0,8515
R01AB85 Xylometazoline+ Dexpanthenol (N) 1834160 ml 0,8 ml 4,7157
R01AC Antiallergic agents, excl. corticosteroids 0,4075
R01AC01 Cromoglicic acid (N) 0,3 g 0,04 g <0,0001
R01AC03 Azelastine (N) 110,95 g 0,56 mg 0,4075
37/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R01AD Corticosteroids 10,9270
R01AD01 Beclometasone (N) 0,66 g 0,4 mg 0,0034
R01AD05 Budesonide (N) 38,86 g 0,2 mg 0,3996
R01AD08 Fluticasone (N) 91,833 g 0,2 mg 0,9444
R01AD09 Mometasone (N) 507,654 g 0,2 mg 5,2208
R01AD12 Fluticasone furoate (N) 203,1018 g 0,11 mg 3,7977
R01AD81 Fluticasone+ Azelastine (N) 1090800 dose 4 dose 0,5609
R01AX Other nasal preparations
R01AX06 Mupirocin (N) 57 g
R01AX83 Retinol+ Tocopherol (N) 145160 ml
R01B NASAL DECONGESTANTS FOR SYSTEMIC USE 3,3951
R01BA Sympathomimetics 3,3951
R01BA02 Pseudoephedrine (O) 233819,64 g 0,24 g 2,0039
R01BA81 Pseudoephedrine+ Triprolidine (O) 45644,16 g 0,24 g 0,3912
R01BA84 Pseudoephedrine+ Guaifenesin (O) 4371,6 g 0,24 g 0,0375
R01BA89 Pseudoephedrine+ Loratadine (O) 15054,48 g 0,24 g 0,1290
R01BA93 Pseudoephedrine+ Cetirizine (O) 97258,56 g 0,24 g 0,8335
R02 THROAT PREPARATIONS 4,0793
R02A THROAT PREPARATIONS 4,0793
R02AA Antiseptics 3,3789
R02AA06 Cetylpyridinium chloride (O) 216 pieces
R02AA82 Benzydamine+ Cetylpyridinium chloride (O) 1671090 ml
R02AA82 Benzydamine+ Cetylpyridinium chloride (O) 3614032 pieces 6 pieces 1,2389
R02AA89 Povidone, iodinated+ Allantoin (O) 527070 ml
R02AA92 Dequalinium+ Cinchocaine (O) 1959760 pieces 6 pieces 0,6718
R02AA94 Amylmetacresol+ Dichlorobenzyl alcohol (O) 672432 pieces 6 pieces 0,2305
R02AA95 Amylmetacresol+ Dichlorobenzyl alcohol+ Levomenthol
(O) 2198400 pieces 6 pieces 0,7536
R02AA96 Amylmetacresol+ Dichlorobenzyl alcohol+ Ascorbic acid
(O) 1411872 pieces 6 pieces 0,4840
R02AX Other throat preparations 0,7004
R02AX01 Flurbiprofen (O) 14982,31 g 44 mg 0,7004
R02AX80 Thymi herba+ Sage leaf (Salvia officinalis) (O) 42975 ml
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES 28,1110
R03A ADRENERGICS, INHALANTS 20,6345
R03AC Selective beta-2-adrenoceptor agonists 3,5820
R03AC02 Salbutamol (I) 916,728 g 0,8 mg 2,3570
R03AC02 Salbutamol (I) 1944,6 g 0,01 g 0,4000
R03AC04 Fenoterol (I) 55,96 g 0,6 mg 0,1918
R03AC12 Salmeterol (I) 2,712 g 0,1 mg 0,0558
R03AC13 Formoterol (I) 4,3049 g 0,024 mg 0,3689
R03AC18 Indacaterol (I) 15,2055 g 0,15 mg 0,2085
R03AK Adrenergics in combination with corticosteroids or other
drugs, excl. anticholinergics 12,8464
R03AK06 Salmeterol+ Fluticasone (I) 448800 dose 4 dose 0,2308
R03AK06 Salmeterol+ Fluticasone (I) 1897200 dose 2 dose 1,9511
R03AK07 Formoterol+ Budesonide (I) 983880 dose 2 dose 1,0118
R03AK07 Formoterol+ Budesonide (I) 6624120 dose 4 dose 3,4062
R03AK08 Formoterol+ Beclometasone (I) 4172040 dose 4 dose 2,1453
R03AK10 Vilanterol+ Fluticasone furoate (I) 1975680 dose 1 dose 4,0637
R03AK13 Salbutamol+ Beclometasone (I) 72800 dose 4 dose 0,0374
R03AL Adrenergics in combinations with anticholinergics incl.
triple combinations with corticosteroids 4,2061
R03AL01 Fenoterol+ Ipratropium bromide (I) 193320 ml 16 ml 0,0249
R03AL01 Fenoterol+ Ipratropium bromide (I) 2595400 dose 6 dose 0,8897
R03AL03 Vilanterol+ Umeclidinium (I) 434220 dose 1 dose 0,8931
R03AL04 Indacaterol+ Glycopyrronium (I) 133650 dose 1 dose 0,2749
R03AL05 Formoterol+ Aclidinium (I) 366480 dose 2 dose 0,3769
R03AL06 Olodaterol+ Tiotropium (I) 627900 dose 2 dose 0,6457
R03AL07 Formoterol+ Glycopyrronium (I) 308280 dose 4 dose 0,1585
R03AL08 Vilanterol+ Umeclidinium+ Fluticasone furoate (I) 132300 dose 1 dose 0,2721
38/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R03AL09 Formoterol+ Glycopyrronium+ Beclometasone (I) 1070520 dose 4 dose 0,5505
R03AL11 Formoterol+ Glycopyrronium+ Budesonide (I) 232800 dose 4 dose 0,1197
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY
DISEASES, INHALANTS 4,5684
R03BA Glucocorticoids 1,6311
R03BA01 Beclometasone (I) 0,2 g 1,5 mg 0,0003
R03BA02 Budesonide (I) 233,16 g 1,5 mg 0,3197
R03BA02 Budesonide (I) 273,104 g 0,8 mg 0,7022
R03BA05 Fluticasone (I) 177,642 g 0,6 mg 0,6090
R03BB Anticholinergics 2,9372
R03BB01 Ipratropium bromide (I) 17,116 g 0,12 mg 0,2934
R03BB01 Ipratropium bromide (I) 30,28 g 0,3 mg 0,2076
R03BB04 Tiotropium (I) 3,1293 g 0,005 mg 1,2873
R03BB05 Aclidinium (I) 119,7647 g 0,644 mg 0,3825
R03BB06 Glycopyrronium (I) 5,4635 g 44 mcg 0,2554
R03BB07 Umeclidinium (I) 13,6653 g 55 mcg 0,5110
R03C ADRENERGICS FOR SYSTEMIC USE 0,1271
R03CC Selective beta-2-adrenoceptor agonists 0,1271
R03CC02 Salbutamol (O) 741,18 g 0,012 g 0,1270
R03CC02 Salbutamol (P) 0,105 g 0,012 g <0,0001
R03D OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE
AIRWAY DISEASES 2,7811
R03DA Xanthines 0,9773
R03DA04 Theophylline (O) 187340 g 0,4 g 0,9633
R03DA05 Aminophylline (O) 22,5 g 0,1 g 0,0005
R03DA05 Aminophylline (P) 3955,2 g 0,6 g 0,0136
R03DC Leukotriene receptor antagonists 1,7105
R03DC03 Montelukast (O) 8316,196 g 0,01 g 1,7105
R03DX Other systemic drugs for obstructive airway diseases 0,0933
R03DX05 Omalizumab (P) 244,95 g 0,016 g 0,0315
R03DX07 Roflumilast (O) 0,03 g 0,5 mg 0,0001
R03DX09 Mepolizumab (P) 61,1 g 3,6 mg 0,0349
R03DX10 Benralizumab (P) 7,02 g 0,54 mg 0,0267
R05 COUGH AND COLD PREPARATIONS 10,6552
R05C EXPECTORANTS, EXCL. COMBINATIONS WITH
COUGH SUPPRESSANTS 10,4046
R05CA Expectorants
R05CA12 Hederae helicis folium (O) 2412,8 g
R05CA12 Hederae helicis folium (O) 350670 pieces
R05CA12 Hederae helicis folium (O) 10077080 ml
R05CA86 Iceland moss (O) 12608100 ml
R05CA87
Distillate form a mixture of rectified essential oils:
eucalyptus oil, sweet orange oil, common myrtle oil,
lemon oil (O)
2963100 pieces
R05CA88 Thymi herba+ Wild thyme+ Plantago (O) 366000 ml
R05CA89 Thymi herba+ Hederae helicis folium (O) 582700 ml
R05CA91 Thymi herba+ Marshmallow root (O) 408620 pieces
R05CA91 Thymi herba+ Marshmallow root (O) 7109070 ml
R05CA92 Thymi herba (O) 207760 pieces
R05CB Mucolytics 10,4046
R05CB01 Acetylcysteine (I, P) 1011 g
R05CB01 Acetylcysteine (O) 1552918,8 g 0,5 g 6,3882
R05CB01 Acetylcysteine (P) 6850,5 g
R05CB02 Bromhexine (O) 9909,04 g 0,024 g 0,8492
R05CB03 Carbocisteine (O) 209465 g 1,5 g 0,2872
R05CB06 Ambroxol (O) 166825,5 g 0,12 g 2,8595
R05CB13 Dornase alfa (I) 24,855 g 2,5 mg 0,0204
R05D COUGH SUPPRESSANTS, EXCL. COMBINATIONS
WITH EXPECTORANTS 0,1212
R05DB Other cough suppressants 0,1212
39/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R05DB09 Oxeladin (O) 4714,45 g 0,08 g 0,1212
R05DB80 Marshmallow root+ Tiliae flos+ Plantago (O) 8748 g
R05F COUGH SUPPRESSANTS AND EXPECTORANTS,
COMBINATIONS 0,1293
R05FA Opium derivatives and expectorants 0,1293
R05FA80 Codeine+ Guaifenesin (O) 1886550 ml 30 ml 0,1293
R05X OTHER COLDPREPARATIONS
R05XA Other cold combination preparations
R05XA80 Gentian root+ Primula flowers+ Rumex acetosa+
Sambucus nigra flower+ Verbena herb (O) 2630920 pieces
R05XA80 Gentian root+ Primula flowers+ Rumex acetosa+
Sambucus nigra flower+ Verbena herb (O) 2804500 ml
R05XA82 Ibuprofen+ Pseudoephedrine (O) 5776,8 g
R06 ANTIHISTAMINES FOR SYSTEMIC USE 21,2726
R06A ANTIHISTAMINES FOR SYSTEMIC USE 21,2726
R06AA Aminoalkyl ethers 0,4369
R06AA02 Diphenhydramine (P) 18,6 g
R06AA04 Clemastine (O) 376,76 g 0,002 g 0,3875
R06AA04 Clemastine (P) 48,09 g 0,002 g 0,0495
R06AE Piperazine derivatives 11,1495
R06AE07 Cetirizine (O) 51785,925 g 0,01 g 10,6516
R06AE09 Levocetirizine (O) 1210,36 g 0,005 g 0,4979
R06AX Other antihistamines for systemic use 9,6861
R06AX02 Cyproheptadine (O) 0,12 g 0,012 g <0,0001
R06AX13 Loratadine (O) 19167,6 g 0,01 g 3,9425
R06AX17 Ketotifen (O) 2,28 g 0,002 g 0,0023
R06AX22 Ebastine (O) 7157,9 g 0,01 g 1,4723
R06AX27 Desloratadine (O) 3293,32 g 0,005 g 1,3548
R06AX28 Rupatadine (O) 966,08 g 0,01 g 0,1987
R06AX29 Bilastine (O) 26404,7 g 20 mg 2,7155
R07 OTHER RESPIRATORY SYSTEM PRODUCTS 0,0012
R07A OTHER RESPIRATORY SYSTEM PRODUCTS 0,0012
R07AA Lung surfactants 0,0003
R07AA81 Phospholipid fraction, porcine lung (endotrach) 22,2 g 0,16 g 0,0003
R07AX Other respiratory system products 0,0009
R07AX02 ivacaftor (O) 130,2 g 0,3 g 0,0009
R07AX32 Ivacaftor+ Tezacaftor+ Elexacaftor (O) 155,4 g
S SENSORY ORGANS 35,0366
S01 OPHTHALMOLOGICALS 35,0366
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA01 Chloramphenicol (S) 253890 ml
S01AA12 Tobramycin (S) 37000 ml
S01AA12 Tobramycin (S) 55947,5 g
S01AA13 Fusidic acid (S) 57820 g
S01AD Antivirals
S01AD03 Aciclovir (S) 3915 g
S01AE Fluoroquinolones
S01AE03 Ciprofloxacin (S) 11,88 g
S01AE03 Ciprofloxacin (S) 13710 ml
S01AE05 Levofloxacin (S) 34065 ml
S01AE07 Moxifloxacin (S) 18235 ml
S01AX Other antiinfectives
S01AX15 Propamidine (S) 210 ml
S01AX18 Povidone, iodinated (S) 552 ml
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA01 Dexamethasone (S) 265 pieces
S01BA01 Dexamethasone (S) 22093 g
S01BA01 Dexamethasone (S) 155020 ml
S01BA02 Hydrocortisone (S) 3351 g
40/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
S01BA04 Prednisolone (S) 0,325 g
S01BA09 Clobetasone (S) 49280 ml
S01BA14 Loteprednol (S) 5675 ml
S01BC Antiinflammatory agents, non-steroids
S01BC03 Diclofenac (S) 30 ml
S01BC05 Ketorolac (S) 10000 ml
S01BC10 Nepafenac (S) 22305 ml
S01BC11 Bromfenac (S) 19230 ml
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES
IN COMBINATION
S01CA Corticosteroids and antiinfectives in combination
S01CA80 Dexamethasone+ Neomycin+ Polymyxin B (S) 82025 ml
S01CA81 Dexamethasone+ Tobramycin (S) 16495,5 g
S01CA81 Dexamethasone+ Tobramycin (S) 41260 ml
S01CA82 Dexamethasone+ Chloramphenicol (S) 55205,5 g
S01CA82 Dexamethasone+ Chloramphenicol (S) 511320 ml
S01CA84 Dexamethasone+ Levofloxacin (S) 7140 ml
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS 35,0366
S01EA Sympathomimetics in glaucoma therapy 0,0312
S01EA05 Brimonidine (S) 3030 ml 0,2 ml 0,0312
S01EB Parasympathomimetics 0,0191
S01EB01 Pilocarpine (S) 3200 ml 0,4 ml 0,0165
S01EB02 Carbachol (S) 510 ml 0,4 ml 0,0026
S01EC Carbonic anhydrase inhibitors 3,7624
S01EC01 Acetazolamide (O) 26065 g 0,75 g 0,0715
S01EC01 Acetazolamide (P) 336 g 0,75 g 0,0009
S01EC03 Dorzolamide (S) 150840 ml 0,3 ml 1,0342
S01EC04 Brinzolamide (S) 153490 ml 0,2 ml 1,5785
S01EC80 Brinzolamide+ Brimonidine (S) 104750 ml 0,2 ml 1,0773
S01ED Beta blocking agents 24,0230
S01ED01 Timolol (S) 25110 ml 0,2 ml 0,2582
S01ED01 Timolol (S) 233580 g 40 mg 12,0110
S01ED02 Betaxolol (S) 75795 ml 0,2 ml 0,7795
S01ED80 Timolol+ Dorzolamide (S) 304195 ml 0,2 ml 3,1284
S01ED81 Timolol+ Travoprost (S) 33010 ml 0,2 ml 0,3395
S01ED82 Timolol+ Bimatoprost (S) 100092 ml 0,2 ml 1,0294
S01ED83 Timolol+ Brinzolamide (S) 226220 ml 0,2 ml 2,3265
S01ED84 Timolol+ Latanoprost (S) 75582,5 ml 0,2 ml 0,7773
S01ED85 Timolol+ Tafluprost (S) 327994 ml 0,2 ml 3,3732
S01EE Prostaglandin analogues 7,2010
S01EE01 Latanoprost (S) 266235 ml 0,1 ml 5,4761
S01EE03 Bimatoprost (S) 153 ml 0,1 ml 0,0031
S01EE04 Travoprost (S) 51247,5 ml 0,1 ml 1,0541
S01EE05 Tafluprost (S) 97389 ml 0,3 ml 0,6677
S01F MYDRIATICS AND CYCLOPLEGICS
S01FA Anticholinergics
S01FA01 Atropine (S) 525 ml
S01FA04 Cyclopentolate (S) 34070 ml
S01FA06 Tropicamide (S) 15405 ml
S01FA80 Tropicamide+ Phenylephrine+ Lidocaine (int.cam) 300 pieces
S01FB Sympathomimetics excl. antiglaucoma preparations
S01FB01 Phenylephrine (S) 9435 ml
S01G DECONGESTANTS AND ANTIALLERGICS
S01GA Sympathomimetics used as decongestants
S01GA02 Tetryzoline (S) 209505 ml
S01GX Other antiallergics
S01GX01 Cromoglicic acid (S) 114020 ml
S01GX07 Azelastine (S) 46938 ml
S01GX09 Olopatadine (S) 48930 ml
S01H LOCAL ANESTHETICS
41/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
S01HA Local anesthetics
S01HA02 Oxybuprocaine (S) 500 ml
S01HA03 Tetracaine (S) 27100 ml
S01HA04 Proxymetacaine (S) 34980 ml
S01J DIAGNOSTIC AGENTS
S01JA Colouring agents
S01JA01 Fluorescein (P) 4560 ml
S01JA81 Fluorescein+ Oxybuprocaine+ Chlorobutanol (S) 2985 ml
S01K SURGICAL AIDS
S01KA Viscoelastic substances
S01KA02 Hypromellose (S) 6540 ml
S01L OCULAR VASCULAR DISORDER AGENTS
S01LA Antineovascularisation agents
S01LA05 aflibercept (S) 196 pieces
S01LA06 Brolucizumab (S) 135 pieces
S01X OTHER OPHTHALMOLOGICALS
S01XA Other ophthalmologicals
S01XA03 Sodium chloride (S) 658 g
S01XA18 Ciclosporin (S) 18936 ml
S01XA80 Retinol+ Dexpanthenol (S) 6849,5 g
S01XA81 Carbomer (S) 174150 g
S01XA82 Hypromellose (S) 205240 ml
S01XA85 Hypromellose+ Dextran (S) 504105 ml
S02 OTOLOGICALS
S02C CORTICOSTEROIDS AND ANTIINFECTIVES IN
COMBINATION
S02CA Corticosteroids and antiinfectives in combination
S02CA81 Dexamethasone+ Neomycin+ Acetic acid, glacial (A) 3840 ml
S02CA82 Hydrocortisone+ Ciprofloxacin (A) 146870 ml
S02D OTHER OTOLOGICALS
S02DA Analgesics and anesthetics
S02DA81 Phenazone+ Lidocaine (A) 2100 ml
V VARIOUS 0,1892
V01 ALLERGENS
V01A ALLERGENS
V01AA Allergen extracts
V01AA02 Grass pollen allergen extract (O) 146 pieces
V01AA02 Grass pollen allergen extract (P) 243 pieces
V01AA03 House dust mites (O) 115 pieces
V01AA03 House dust mites (P) 327 pieces
V01AA05 Tree pollen allergen extract (P) 289 pieces
V01AA05 Tree pollen allergen extract (SL) 210 pieces
V01AA07 Allergen extracts - insects (P) 594 pieces
V01AA11 Allergen extracts - animals (O) 24 pieces
V01AA80 Tree and grass pollen (O) 48 pieces
V01AA80 Tree and grass pollen (P) 7 pieces
V01AA83 Grass pollen allergen extract+ Flowers (O) 4 pieces
V01AA84 Tree and flower pollen (O) 10 pieces
V03 ALL OTHER THERAPEUTIC PRODUCTS 0,1892
V03A ALL OTHER THERAPEUTIC PRODUCTS 0,1892
V03AB Antidotes
V03AB06 Sodium thiosulfate (P) 625 g
V03AB14 Protamine sulfate (P) 266,75 g
V03AB15 Naloxone (N) 3,492 g
V03AB15 Naloxone (P) 2,558 g
V03AB16 Ethanol (P) 10600 ml
V03AB17 Methylthioninium chloride (P) 148,1 g
V03AB19 Physostigmine (P) 0,16 g
V03AB21 Potassium iodide (O) 12381,2 g
V03AB24 Digitalis antitoxin (P) 2,8 g
42/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
V03AB25 Flumazenil (P) 0,09 g
V03AB32 Glutathione (P) 4212 g
V03AB33 Hydroxocobalamin (P) 100 g
V03AB34 Fomepizole (P) 20 g
V03AB35 Sugammadex (P) 148 g
V03AB37 Idarucizumab (P) 210 g
V03AB80 Sodium calcium edetate (P) 1050 g
V03AC Iron chelating agents
V03AC01 Deferoxamine (P) 65 g
V03AC02 Deferiprone (O) 550 g
V03AC03 Deferasirox (O) 3985,2 g
V03AE Drugs for treatment of hyperkalemia and
hyperphosphatemia 0,1412
V03AE01 Polystyrene sulfonate (O, R) 1638448,5 g 45 g 0,0749
V03AE02 Sevelamer (O) 147456 g 6,4 g 0,0474
V03AE03 Lanthanum (O) 20722,5 g 2,25 g 0,0189
V03AF Detoxifying agents for antineoplastic treatment 0,0480
V03AF01 Mesna (P) 4122 g
V03AF03 Calcium folinate (O) 44,1 g 0,06 g 0,0015
V03AF07 Rasburicase (P) 0,729 g 0,014 g 0,0001
V03AF10 Sodium levofolinate (P) 676,65 g 0,03 g 0,0464
V03AH Drugs for treatment of hypoglycemia
V03AH01 Diazoxide (O) 50 g
V03AN Medical gases
V03AN01 Oxygen (I) 464275000 ml
V03AN05 Air, medicinal (I) 5630000 ml
V03AX Other therapeutic products
V03AX81 herbal preparation (C) 33000 g
V03AX81 herbal preparation (O) 680190 pieces
V03AX81 herbal preparation (O) 9012440 ml
V03AX82 homeopathic preparations (A) 479 pieces
V03AX82 homeopathic preparations (C) 13626 pieces
V03AX82 homeopathic preparations (O) 1516295 pieces
V04 DIAGNOSTIC AGENTS
V04C OTHER DIAGNOSTIC AGENTS
V04CD Tests for pituitary function
V04CD01 Metyrapone (O) 25 g
V04CD04 Corticorelin (P) 0,0002 g
V04CF Tuberculosis diagnostics
V04CF01 Tuberculin (P) 5520 U
V04CJ Tests for thyreoidea function
V04CJ02 Protirelin (P) 0,008 g
V04CX Other diagnostic agents
V04CX01 Indocyanine green (P) 7,9 g
V04CX03 Methacholine (I) 67,554 g
V04CX04 Mannitol (I) 102 pieces
V04CX06 Hexaminolevulinate (P) 21,08 g
V04CX09 Patent blue (P) 4 g
V04CX87 Carbon monoxide+ Helium (I) 60000 ml
V04CX89 Carbon monoxide+ Acetylene+ Methane+ Oxygen+
Nitrogen (I) 340000 ml
V07 ALL OTHER NON-THERAPEUTIC PRODUCTS
V07A ALL OTHER NON-THERAPEUTIC PRODUCTS
V07AB Solvents and diluting agents, incl. irrigating solutions
V07AB80 Sodium chloride (P) 9892335 ml
V07AB83 Water for injection (NA) 24650600 ml
V07AB83 Water for injection (P) 2000 ml
V08 CONTRAST MEDIA
V08A X-RAY CONTRAST MEDIA, IODINATED
43/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
V08AA Watersoluble, nephrotropic, high osmolar X-ray contrast
media
V08AA01 Sodium amidotrizoate+ Meglumine Amidotrizoate (P) 4000 ml
V08AB Watersoluble, nephrotropic, low osmolar X-ray contrast
media
V08AB02 Iohexol (P) 2051030 g
V08AB05 Iopromide (P) 1234938,5 g
V08AB09 Iodixanol (P) 3264700 g
V08AD Non-watersoluble X-ray contrast media
V08AD01 Ethyl esters of iodised fatty acids from poppyseed oil (P) 264 g
V08B X-RAY CONTRAST MEDIA, NON-IODINATED
V08BA Barium sulfate containing X-ray contrast media
V08BA01 Barium sulfate (O) 283,2 pieces
V08BA01 Barium sulfate (O) 134000 ml
V08C MAGNETIC RESONANCE IMAGING CONTRAST
MEDIA
V08CA Paramagnetic contrast media
V08CA01 Gadopentetic acid (P) 4780 ml
V08CA02 Gadoteric acid (P) 75750 ml
V08CA09 Gadobutrol (P) 116275 ml
V08CA10 Gadoxetic acid (P) 6780 ml
V08D ULTRASOUND CONTRAST MEDIA
V08DA Ultrasound contrast media
V08DA05 Sulfur hexafluoride (P) 275 ml
V09 DIAGNOSTIC RADIOPHARMACEUTICALS
V09A CENTRAL NERVOUS SYSTEM
V09AB Iodine (123I) compounds
V09AB03 Ioflupane (123I) (P) 455 ml
V09F THYROID
V09FX Various thyroid diagnostic radiopharmaceuticals
V09FX01 Technetium (99mTc)pertechnetate (S) 71 pieces
V10 THERAPEUTIC RADIOPHARMACEUTICALS
V10X OTHER THERAPEUTIC RADIOPHARMACEUTICALS
V10XA Iodine (131I) compounds
V10XA01 Sodium iodide (131I) (O) 129 pieces
44/44
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A ALIMENTARY TRACT AND METABOLISM 184,6875
A01 STOMATOLOGICAL PREPARATIONS 0,0691
A01A STOMATOLOGICAL PREPARATIONS 0,0691
A01AB Antiinfectives and antiseptics for local oral treatment 0,0691
A01AB08 Neomycin(O) 200 pieces
A01AB09 Miconazole(O) 6699,2 g 0,2 g 0,0691
A01AB12 Hexetidine(O) 1386880 ml
A01AB82 Demeclocycline+Triamcinolone(dental) 770 g
A01AD Other agents for local oral treatment
A01AD80 Lidocaine+Cetylpyridinium chloride(gingival) 199970 g
A01AD81 Lidocaine+Cetrimide(O) 50250 g
A01AD82 Choline salicylate(O) 160048 pieces
A01AD83 Lidocaine+Chamomille extract(O) 386240 g
A01AD90 Lidocaine+Paraformaldehyde(dental) 198 g
A02 DRUGS FOR ACID RELATED DISORDERS 61,1483
A02A ANTACIDS 1,2544
A02AD Combinations and complexes of aluminium, calcium and
magnesium compounds 1,2544
A02AD81 Aluminium hydroxide+Magnesium hydroxide(O) 950000 pieces 10 pieces 0,1959
A02AD81 Aluminium hydroxide+Magnesium hydroxide(O) 4863894 ml 50 ml 0,2006
A02AD83 Calcium carbonate+Magnesium carbonate(O) 4160664 pieces 10 pieces 0,8580
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-
OESOPHAGEAL REFLUX DISEASE (GORD) 59,8939
A02BA H2-receptor antagonists 0,0212
A02BA02 Ranitidine(P) 1971,75 g 0,3 g 0,0136
A02BA03 Famotidine(O) 148 g 0,04 g 0,0076
A02BC Proton pump inhibitors 59,8616
A02BC01 Omeprazole(O) 303243,2 g 0,02 g 31,2654
A02BC02 Pantoprazole(O) 303796,5 g 0,04 g 15,6612
A02BC02 Pantoprazole(P) 395,6 g 0,04 g 0,0204
A02BC03 Lansoprazole(O) 13,86 g 0,03 g 0,0010
A02BC05 Esomeprazole(O) 184510,48 g 0,03 g 12,6824
A02BC05 Esomeprazole(P) 3364 g 0,03 g 0,2312
A02BC08 Vonoprazan(O) 4 g
A02BD Combinations for eradication of Helicobacter pylori 0,0016
A02BD08 Bismuth subcitrate+Tetracycline+Metronidazole (O) 9600 pieces 12 pieces 0,0016
A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux
disease (GORD) 0,0094
A02BX02 Sucralfate(O) 15790 g 4 g 0,0081
A02BX03 Pirenzepine(O) 60 g 0,1 g 0,0012
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL
DISORDERS 8,5944
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL
DISORDERS 7,6949
A03AA Synthetic anticholinergics, esters with tertiary amino group 1,4436
A03AA04 Mebeverine(O) 210024 g 0,3 g 1,4436
A03AD Papaverine and derivatives 4,6591
A03AD01 Papaverine hydrochloride(P) 102 g 0,1 g 0,0021
A03AD02 Drotaverine(O) 222498,4 g 0,1 g 4,5881
A03AD02 Drotaverine(P) 3344 g 0,1 g 0,0690
A03AX Other drugs for functional gastrointestinal disorders 1,5921
A03AX13 Simeticone(O) 386047,5729 g 0,5 g 1,5921
A03B BELLADONNA AND DERIVATIVES, PLAIN 0,0823
A03BA Belladonna alkaloids, tertiary amines 0,0710
A03BA01 Atropine(O, P) 17,52 g 0,0015 g 0,0241
A03BA01 Atropine(P) 34,16 g 0,0015 g 0,0470
A03BB Belladonna alkaloids, semisynthetic, quaternary ammonium
compounds 0,0112
A03BB01 Hyoscine butylbromide(O) 30,4 g 0,06 g 0,0010
A03BB01 Hyoscine butylbromide(P) 296,6 g 0,06 g 0,0102
1/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A03F PROPULSIVES 0,8173
A03FA Propulsives 0,8173
A03FA01 Metoclopramide(O) 10122,5 g 0,03 g 0,6958
A03FA01 Metoclopramide(P) 1544,8 g 0,03 g 0,1062
A03FA03 Domperidone(O) 222,9 g 0,03 g 0,0153
A04 ANTIEMETICS AND ANTINAUSEANTS 0,1167
A04A ANTIEMETICS AND ANTINAUSEANTS 0,1167
A04AA Serotonin (5-HT3) antagonists 0,1082
A04AA01 Ondansetron(P) 185,74 g 0,016 g 0,0239
A04AA02 Granisetron(O) 56,95 g 0,002 g 0,0587
A04AA02 Granisetron(P) 34,23 g 0,003 g 0,0235
A04AA80 Palonosetron+Netupitant(O) 963 pieces 1 pieces 0,0020
A04AD Other antiemetics 0,0086
A04AD01 Scopolamine(TD) 45 pieces 1 pieces 0,0001
A04AD12 Aprepitant(O) 233,985 g 0,165 g 0,0029
A04AD81 Fosaprepitant(P) 256,05 g 0,095 g 0,0056
A05 BILE AND LIVER THERAPY 2,0206
A05A BILE THERAPY 0,5389
A05AA Bile acids and derivatives 0,5389
A05AA02 Ursodeoxycholic acid(O) 195987,5 g 0,75 g 0,5389
A05B LIVER THERAPY, LIPOTROPICS 1,4818
A05BA Liver therapy 1,4818
A05BA03 Silymarin(O) 2076650 pieces
A05BA80 Phospholipids from Soya Beans(O) 1349910 pieces 3 pieces 0,9279
A05BA80 Phospholipids from Soya Beans(O) 1611640 pieces 6 pieces 0,5539
A05BA80 Phospholipids from Soya Beans(P) 1045 pieces
A06 DRUGS FOR CONSTIPATION 17,0341
A06A DRUGS FOR CONSTIPATION 17,0341
A06AB Contact laxatives 7,3954
A06AB02 Bisacodyl(O) 14101,2 g 0,01 g 2,9078
A06AB02 Bisacodyl(R) 719,6 g 0,01 g 0,1484
A06AB06 Senna glycosides(O) 4880 pieces 1 pieces 0,0101
A06AB08 Sodium picosulfate(O) 10490,3565 g 0,005 g 4,3264
A06AB80 Sodium picosulfate+Magnesium oxide+Citric acid(O) 2768 pieces 2 pieces 0,0029
A06AD Osmotically acting laxatives 8,6893
A06AD11 Lactulose(O) 26737036,2 g 6,7 g 8,2289
A06AD15 Macrogol(O) 2232640 g 10 g 0,4604
A06AD80 Macrogol+Sodium citrate+Citric acid+Sodium
chloride+Potassium chloride(O) 28200 ml
A06AD81 Sodium sulphate, anhydrous+Potassium chloride+Sodium
chloride+Macrogol+Sodium hydrogen carbonate(O) 33932 pieces
A06AD83
Macrogol+Sodium sulphate, anhydrous+Sodium
chloride+Potassium chloride+Ascorbic acid+Sodium
ascorbate(O)
5859 pieces
A06AD85 Sodium sulphate, anhydrous+magnesium sulfate
heptahydrate+Potassium sulphate(O) 825088 ml
A06AG Enemas 0,9134
A06AG11 Laurilsulfate, incl. combinations+Sorbitol+Sodium citrate(R) 442972 pieces 1 pieces 0,9134
A06AH Peripheral opioid receptor antagonists 0,0359
A06AH03 Naloxegol(O) 435,75 g 25 mg 0,0359
A07 ANTIDIARRHEALS, INTESTINAL
ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS 4,2629
A07A INTESTINAL ANTIINFECTIVES 0,0027
A07AA Antibiotics 0,0027
A07AA02 Nystatin(O) 120000000 U 1500000 U 0,0002
A07AA11 Rifaximin(O) 698,4 g 0,6 g 0,0024
A07AA12 Fidaxomicin(O) 28 g 0,4 g 0,0001
A07B INTESTINAL ADSORBENTS 0,3750
A07BC Other intestinal adsorbents 0,3750
2/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A07BC05 Diosmectidum(O) 1636560 g 9 g 0,3750
A07C ELECTROLYTES WITH CARBOHYDRATES
A07CA Oral rehydration salt formulations
A07CA80 Sodium chloride+Potassium chloride+Sodium
citrate+Glucose(O) 67280 pieces
A07D ANTIPROPULSIVES 0,9140
A07DA Antipropulsives 0,9140
A07DA03 Loperamide(O) 4432,352 g 0,01 g 0,9140
A07E INTESTINAL ANTIINFLAMMATORY AGENTS 2,3751
A07EA Corticosteroids acting locally 0,0096
A07EA06 Budesonide(O) 42,03 g 0,009 g 0,0096
A07EA06 Budesonide(R) 1,0304 g
A07EC Aminosalicylic acid and similar agents 2,3655
A07EC01 Sulfasalazine(O) 802500 g 2 g 0,8274
A07EC02 Mesalazine(O) 1022258 g 1,5 g 1,4053
A07EC02 Mesalazine(R) 96600 g 1,5 g 0,1328
A07F ANTIDIARRHEAL MICROORGANISMS 0,5961
A07FA Antidiarrheal microorganisms 0,5961
A07FA02 Saccharomyces boulardii(O) 289067,5 g 1 g 0,5961
A07X OTHER ANTIDIARRHEALS
A07XA Other antidiarrheals
A07XA04 Racecadotril(O) 2480 g
A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0543
A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0543
A08AA Centrally acting antiobesity products 0,0538
A08AA62 Bupropione+Naltrexone(O) 104272 pieces 4 pieces 0,0538
A08AB Peripherally acting antiobesity products 0,0005
A08AB01 Orlistat(O) 95,76 g 0,36 g 0,0005
A09 DIGESTIVES, INCL. ENZYMES 1,6877
A09A DIGESTIVES, INCL. ENZYMES 1,6877
A09AA Enzyme preparations 1,6875
A09AA02 Lipase+Amylase+Protease(O) 3273341 pieces 4 pieces 1,6875
A09AC Enzyme and acid preparations, combinations 0,0002
A09AC80 Pepsin+Betaine(O) 300 pieces 3 pieces 0,0002
A10 DRUGS USED IN DIABETES 66,9614
A10A INSULINS AND ANALOGUES 15,9557
A10AB Insulins and analogues for injection, fast-acting 6,0469
A10AB01 Insulin (human)(P) 1110000 U 40 U 0,0572
A10AB04 Insulin lispro(P) 21273000 U 40 U 1,0967
A10AB05 Insulin aspart(P) 82890000 U 40 U 4,2731
A10AB06 Insulin glulisine(P) 12024000 U 40 U 0,6199
A10AC Insulins and analogues for injection, intermediate-acting 0,0653
A10AC01 Insulin (human)(P) 1266000 U 40 U 0,0653
A10AD Insulins and analogues for injection, intermediate- or long-
acting combined with fast-acting 0,8005
A10AD04 Insulin lispro(P) 4824000 U 40 U 0,2487
A10AD05 Insulin aspart(P) 10704000 U 40 U 0,5518
A10AE Insulins and analogues for injection, long-acting 9,0431
A10AE04 Insulin glargine(P) 95778000 U 40 U 4,9375
A10AE05 Insulin detemir(P) 41920500 U 40 U 2,1611
A10AE06 Insulin degludec(P) 33693900 U 40 U 1,7370
A10AE54 Insulin glargine+Lixisenatide(P) 4026000 U 40 U 0,2075
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS 51,0057
A10BA Biguanides 21,2264
A10BA02 Metformin(O) 20587506 g 2 g 21,2264
A10BB Sulfonylureas 12,2232
A10BB01 Glibenclamide(O) 0,018 g 0,01 g <0,0001
A10BB07 Glipizide(O) 855,9 g 0,01 g 0,1765
3/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A10BB09 Gliclazide(O) 205800 g 0,06 g 7,0729
A10BB12 Glimepiride(O) 4824,12 g 0,002 g 4,9738
A10BD Combinations of oral blood glucose lowering drugs 7,6158
A10BD07 Metformin+Sitagliptin(O) 1793120 pieces 2 pieces 1,8488
A10BD08 Metformin+Vildagliptin(O) 1392960 pieces 2 pieces 1,4362
A10BD10 Metformin+Saxagliptin(O) 315960 pieces 2 pieces 0,3258
A10BD11 Metformin+Linagliptin(O) 1196340 pieces 2 pieces 1,2335
A10BD15 Metformin+Dapagliflozin(O) 789208 pieces 2 pieces 0,8137
A10BD19 Linagliptin+Empagliflozin(O) 183900 pieces 1 pieces 0,3792
A10BD20 Metformin+Empagliflozin(O) 1343460 pieces 2 pieces 1,3852
A10BD21 Saxagliptin+Dapagliflozin(O) 92624 pieces 1 pieces 0,1910
A10BD23 Metformin+Ertugliflozin(O) 1232 pieces 1 pieces 0,0025
A10BF Alpha glucosidase inhibitors 0,0011
A10BF01 Acarbose(O) 162,75 g 0,3 g 0,0011
A10BG Thiazolidinediones 0,1208
A10BG03 Pioglitazone(O) 1757,7 g 0,03 g 0,1208
A10BH Dipeptyl peptidase 4 (DPP-4) inhibitors 4,1024
A10BH01 Sitagliptin(O) 48127,1 g 0,1 g 0,9924
A10BH02 Vildagliptin(O) 8460 g 0,1 g 0,1745
A10BH03 Saxagliptin(O) 538,35 g 5 mg 0,2220
A10BH05 Linagliptin(O) 6579,6 g 5 mg 2,7135
A10BJ Glucagon-like peptide-1 (GLP-1) analogues 2,9082
A10BJ01 Exenatide(P) 5,224 g 0,286 mg 0,0377
A10BJ02 Liraglutide(P) 639,36 g 1,5 mg 0,8789
A10BJ03 Lixisenatide(P) 0,5677 g 20 mcg 0,0585
A10BJ05 Dulaglutide(P) 24,786 g 0,16 mg 0,3194
A10BJ06 Semaglutide(P) 86,079 g 0,11 mg 1,6136
A10BK Sodium-glucose co-transporter 2 (SGLT2) inhibitors 2,8077
A10BK01 Dapagliflozin(O) 5586,3 g 10 mg 1,1519
A10BK03 empagliflozin(O) 14047,35 g 17,5 mg 1,6552
A10BK04 Ertugliflozin(O) 2,52 g 10 mg 0,0005
A11 VITAMINS 13,2321
A11A MULTIVITAMINS, COMBINATIONS 1,5026
A11AA Multivitamins with minerals 1,5026
A11AA03 Multivitamins+Mineral elements(O) 728670 pieces 1 pieces 1,5026
A11B MULTIVITAMINS, PLAIN 0,0001
A11BA Multivitamins, plain 0,0001
A11BA80 Multivitamins(O) 500 ml 10 ml 0,0001
A11C VITAMIN A AND D, INCL. COMBINATIONS OF THE TWO 3,8756
A11CC Vitamin D and analogues 3,8756
A11CC04 Calcitriol(O) 0,1007 g 0,001 mg 0,2077
A11CC05 Colecalciferol(O) 711500000 U 400 U 3,6679
A11CC05 Colecalciferol(P) 7500000 U
A11D VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN
B6 AND B12 1,6079
A11DA Vitamin B1, plain 0,4309
A11DA01 Thiamine(O, P, V) 1050 g 0,05 g 0,0433
A11DA01 Thiamine(P) 9398,5 g 0,05 g 0,3876
A11DA03 Benfotiamine(O) 1754230 pieces
A11DB Vitamin B1 in combination with vitamin B6 and/or vitamin B12 1,1770
A11DB80 Thiamine+Pyridoxine(P) 2345 pieces 1 pieces 0,0048
A11DB81 Benfotiamine+Pyridoxine(O) 207900 pieces 3 pieces 0,1429
A11DB84 Thiamine+Pyridoxine+Cyanocobalamin(O) 428260 pieces 1 pieces 0,8831
A11DB85 Thiamine+Pyridoxine+Cyanocobalamin+Lidocaine(P) 70895 pieces 1 pieces 0,1462
A11E VITAMIN B-COMPLEX, INCL. COMBINATIONS 0,6892
A11EA Vitamin B-complex, plain 0,6892
A11EA80 Thiamine+Nicotinamide+Riboflavin+Calcium
pantothenate+Pyridoxine(O) 334250 pieces 1 pieces 0,6892
A11G ASCORBIC ACID (VITAMIN C), INCL. COMBINATIONS 0,1285
A11GA Ascorbic acid (vitamin C), plain 0,1285
4/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A11GA01 Ascorbic acid(P) 12460 g 0,2 g 0,1285
A11H OTHER PLAIN VITAMIN PREPARATIONS 0,0545
A11HA Other plain vitamin preparations 0,0545
A11HA02 Pyridoxine(O) 90 g 0,16 g 0,0012
A11HA02 Pyridoxine(P) 3746,5 g 0,16 g 0,0483
A11HA03 Tocopherol(O) 120 g 0,2 g 0,0012
A11HA03 Tocopherol(P) 10,5 g 0,2 g 0,0001
A11HA08 Tocofersolan(O) 363 g 0,2 g 0,0037
A11J OTHER VITAMIN PRODUCTS, COMBINATIONS 5,3736
A11JA Combinations of vitamins
A11JA80 Combinations of vitamins(O) 800 ml
A11JB Vitamins with minerals 5,3736
A11JB81 Pyridoxine+Magnesium(O) 6924650 pieces 4 pieces 3,5698
A11JB82
Thiamine+Riboflavin+Pyridoxine+Cyanocobalamin+Ascorbic
acid+Biotin+Nicotinamide+Calcium
pantothenate+Calcium+Magnesium+Folic acid+Zinc(O)
874785 pieces 1 pieces 1,8039
A12 MINERAL SUPPLEMENTS 8,9424
A12A CALCIUM 5,3412
A12AA Calcium 0,8646
A12AA03 Calcium gluconate(P) 36475 g 3 g 0,0251
A12AA04 Calcium carbonate(O) 1221425 g 3 g 0,8396
A12AX Calcium, combinations with vitamin D and/or other drugs 4,4766
A12AX80 Calcium+Colecalciferol(O) 573690 pieces 1 pieces 1,1830
A12AX80 Calcium+Colecalciferol(O) 3194460 pieces 2 pieces 3,2936
A12B POTASSIUM 3,1279
A12BA Potassium 3,1279
A12BA01 Potassium chloride(O) 357570 g 3 g 0,2458
A12BA02 Potassium citrate(O) 2484 g 4 g 0,0013
A12BA80 Potassium chloride+Potassium hydrogen carbonate(O) 7200 pieces
A12BA81 Potassium aspartate+Magnesium aspartate(O) 4151450 pieces 3 pieces 2,8535
A12BA81 Potassium aspartate+Magnesium aspartate(P) 13255 pieces 1 pieces 0,0273
A12C OTHER MINERAL SUPPLEMENTS 0,4733
A12CC Magnesium 0,4733
A12CC04 Magnesium citrate(O) 459040,2 g 2 g 0,4733
A12CX Other mineral products
A12CX83 Phosphate(O) 11900 pieces
A14 ANABOLIC AGENTS FOR SYSTEMIC USE 0,0030
A14A ANABOLIC STEROIDS 0,0030
A14AB Estren derivatives 0,0030
A14AB01 Nandrolone(P) 2,95 g 0,002 g 0,0030
A14B OTHER ANABOLIC AGENTS
A14BX Other anabolic agents
A14BX80 Riboxine(O) 90 g
A16 OTHER ALIMENTARY TRACT AND METABOLISM
PRODUCTS 0,5605
A16A OTHER ALIMENTARY TRACT AND METABOLISM
PRODUCTS 0,5605
A16AA Amino acids and derivatives 0,0018
A16AA01 Levocarnitine(O) 1750 g 2 g 0,0018
A16AA02 Ademetionine(O) 280 g
A16AA81 Glycine(O) 480 g
A16AB Enzymes 0,0056
A16AB02 Imiglucerase(P) 162800 U 300 U 0,0011
A16AB03 Agalsidase alfa(P) 1,281 g 0,001 g 0,0026
A16AB04 Agalsidase beta(P) 1,69 g 0,005 g 0,0007
A16AB07 Alglucosidase alfa(P) 55,4 g 0,1 g 0,0011
A16AB09 Idursulfase(P) 1,152 g
A16AX Various alimentary tract and metabolism products 0,5531
A16AX01 Thioctic acid(O) 157770 g 0,6 g 0,5422
A16AX01 Thioctic acid(P) 177 g 0,6 g 0,0006
5/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A16AX03 Sodium phenylbutyrate(O) 2250 g 20 g 0,0002
A16AX05 Zinc(O) 618,75 g 0,15 g 0,0085
A16AX07 Sapropterin(O) 720 g
A16AX10 Eliglustat(O) 108,192 g 0,168 g 0,0013
A16AX15 Telotristat(O) 67,5 g 0,75 g 0,0002
A16AX80 Creatine(O) 450 g
A16AX81 Copper histidine(P) 0,23 g
B BLOOD AND BLOOD FORMING ORGANS 109,6746
B01 ANTITHROMBOTIC AGENTS 82,5895
B01A ANTITHROMBOTIC AGENTS 82,5895
B01AA Vitamin K antagonists 2,0593
B01AA03 Warfarin(O) 7490 g 0,0075 g 2,0593
B01AB Heparin group 3,1858
B01AB01 Heparin sodium(P) 604000000 U 10000 U 0,1245
B01AB05 Enoxaparin sodium(hem, P) 762976000 U 2000 U 0,7867
B01AB05 Enoxaparin sodium(P) 1755668000 U 2000 U 1,8102
B01AB06 Nadroparin calcium(P) 7353000 U 2850 U 0,0053
B01AB12 Bemiparin sodium(P) 556640000 U 2500 U 0,4591
B01AC Platelet aggregation inhibitors, excl. heparin 54,7718
B01AC04 Clopidogrel(O) 155659,2 g 0,075 g 4,2797
B01AC06 Acetylsalicylic acid (O) 4273554 pieces 1 pieces 8,8124
B01AC11 Iloprost(I) 0,089 g 0,15 mg 0,0012
B01AC11 Iloprost(P) 0,0047 g 50 mcg 0,0002
B01AC16 Eptifibatide(P) 62,94 g 0,2 g 0,0006
B01AC24 Ticagrelor(O) 98666,4 g 0,18 g 1,1303
B01AC27 Selexipag
(O) 3,12 g 1,8 mg 0,0036
B01AC80 Acetylsalicylic acid +Magnesium oxide(O) 19661700 pieces 1 pieces 40,5438
B01AD Enzymes 0,0026
B01AD01 Streptokinase(P) 12500000 U 1500000 U <0,0001
B01AD02 Alteplase(P) 108,02 g 0,1 g 0,0022
B01AD11 Tenecteplase(P) 7,45 g 0,04 g 0,0004
B01AE Direct thrombin inhibitors 2,7382
B01AE07 Dabigatran etexilate(O) 398360,15 g 0,3 g 2,7382
B01AF Direct factor Xa inhibitors 19,8302
B01AF01 Rivaroxaban(O) 102828,25 g 0,02 g 10,6019
B01AF02 Apixaban(O) 43141,8 g 10 mg 8,8961
B01AF03 Edoxaban(O) 9665,1 g 60 mg 0,3322
B01AX Other antithrombotic agents 0,0015
B01AX01 Defibrotide(P) 66 g 1,75 g 0,0001
B01AX05 Fondaparinux sodium(P) 1,75 g 0,0025 g 0,0014
B02 ANTIHEMORRHAGICS 0,1855
B02A ANTIFIBRINOLYTICS 0,1578
B02AA Amino acids 0,1578
B02AA01 Aminocaproic acid(P) 6515 g 16 g 0,0008
B02AA02 Tranexamic acid(O) 111570 g 2 g 0,1150
B02AA02 Tranexamic acid(P) 40637,5 g 2 g 0,0419
B02B VITAMIN K AND OTHER HEMOSTATICS 0,0277
B02BA Vitamin K 0,0037
B02BA01 Phytomenadione(O) 1,5 g 0,02 g 0,0002
B02BA01 Phytomenadione(O, P) 23,3 g 0,02 g 0,0024
B02BA01 Phytomenadione(P) 11,12 g 0,02 g 0,0011
B02BB Fibrinogen 0,0001
B02BB01 Fibrinogen human(P) 262 g 5 g 0,0001
B02BC Local hemostatics
B02BC81 Fibrinogen human+Human thrombin(epil) 687 pieces
B02BD Blood coagulation factors
B02BD01 Human prothrombin complex(P) 207200 U
B02BD02 Human coagulation factor VIII(P) 3485000 U
B02BD03 Factor VIII inhibitor bypassing activity(P) 120000 U
B02BD04 Human coagulation factor IX(P) 726800 U
6/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B02BD05 Human coagulation factor VII(P) 192000 U
B02BD06 Von Willebrand factor, human+Human coagulation factor
VIII(P) 2075250 U
B02BD08 Coagulation factor VIIa(P) 6050000 U
B02BD80 Turoctocog alfa(P) 40000 U
B02BD81 Simoctocog alfa(P) 414000 U
B02BD83 Efmoroctocog alfa(P) 2870750 U
B02BX Other systemic hemostatics 0,0239
B02BX01 Etamsylate(P) 625 g
B02BX04 Romiplostim(P) 0,0718 g 30 mcg 0,0049
B02BX05 Eltrombopag(O) 390,6 g 50 mg 0,0161
B02BX06 Emicizumab(P) 21,045 g 15 mg 0,0029
B03 ANTIANEMIC PREPARATIONS 26,8983
B03A IRON PREPARATIONS 4,2523
B03AA Iron bivalent, oral preparations 2,3296
B03AA07 Ferrous sulphate(O) 225945 g 0,2 g 2,3296
B03AB Iron trivalent, oral preparations
B03AB80 Iron (III) hydroxide polymaltose complex(O) 83378,5 g
B03AC Iron, parenteral preparations 0,1080
B03AC01 Dextriferron(P) 1274 g 0,1 g 0,0263
B03AC02 Iron (III) hydroxide sucrose complex(P) 1351,5 g 0,1 g 0,0279
B03AC06 Iron (III)-hydroxide dextran complex(P) 1534 g 0,1 g 0,0316
B03AC80 Ferric derisomaltose(P) 1076,5 g 0,1 g 0,0222
B03AD Iron in combination with folic acid 1,8147
B03AD02 Ferrous fumarate+Folic acid(O) 508550 pieces 1 pieces 1,0487
B03AD03 Ferrous sulphate+Folic acid(O) 371500 pieces 1 pieces 0,7661
B03AE Iron in other combinations
B03AE81 Ferrous gluconate+Manganese gluconate+Copper
gluconate(O) 1696000 ml
B03AE82 Ferrous fumarate+Folic acid+Ascorbic acid(O) 43600 pieces
B03B VITAMIN B12 AND FOLIC ACID 21,6311
B03BA Vitamin B12 (cyanocobalamin and analogues) 6,4352
B03BA01 Cyanocobalamin(O) 7,9 g 1 mg 0,0163
B03BA01 Cyanocobalamin(P) 62,055 g 0,02 mg 6,3981
B03BA03 Hydroxocobalamin(P) 0,2016 g 0,02 mg 0,0208
B03BB Folic acid and derivatives 15,1959
B03BB01 Folic acid(O) 2947,7 g 0,4 mg 15,1959
B03X OTHER ANTIANEMIC PREPARATIONS 1,0149
B03XA Other antianemic preparations 1,0149
B03XA02 Darbepoetin alfa(P) 1,6123 g 0,0045 mg 0,7388
B03XA03 Methoxy polyethylene glycol-epoetin beta(P) 0,292 g 4 mcg 0,1505
B03XA80 Epoetin beta(P) 60912000 U 1000 U 0,1256
B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B05A BLOOD AND RELATED PRODUCTS
B05AA Blood substitutes and plasma protein fractions
B05AA01 Albumin(P) 701430 g
B05AA06 Gelatin agents(P) 8840000 ml
B05AA81 Dextran+Sodium chloride(P) 23500 ml
B05AA83 Gelatine+Sodium chloride+Potassium chloride+Magnesium
chloride+Sodium lactate(P) 670000 ml
B05AA86 human plasma proteins(P) 505400 ml
B05B I.V. SOLUTIONS
B05BA Solutions for parenteral nutrition
B05BA01 Amino acids(P) 799000 ml
B05BA02 Fat emulsions(P) 156900 ml
B05BA03 Carbohydrates(P) 7160 g
B05BA03 Carbohydrates(P) 67562600 ml
B05BA10 Combinations(P) 17156734 ml
B05BB Solutions affecting the electrolyte balance
B05BB01 Electrolytes(P) 188802500 ml
B05BB81 Sodium chloride+Glucose(P) 250000 ml
7/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B05BC Solutions producing osmotic diuresis
B05BC01 Mannitol(P) 954000 ml
B05C IRRIGATING SOLUTIONS
B05CX Other irrigating solutions
B05CX10 Combinations(NA) 346000 ml
B05D PERITONEAL DIALYTICS
B05DA Isotonic solutions
B05DA80 Isotonic solutions(P) 8830000 ml
B05DB Hypertonic solutions
B05DB80 hypertonic solutions(P) 138214000 ml
B05DB81 Amino acids+Sodium chloride+Calcium chloride
dihydrate+Magnesium chloride hexahydrate+Sodium lactate(P) 220000 ml
B05Z HEMODIALYTICS AND HEMOFILTRATES
B05ZB Hemofiltrates
B05ZB80
Sodium chloride+Potassium chloride+Calcium chloride
dihydrate+Magnesium chloride+Glucose+Sodium hydrogen
carbonate(P)
20430000 ml
B05ZB82
Calcium chloride dihydrate+Magnesium chloride
hexahydrate+Sodium chloride+Sodium hydrogen
carbonate+Potassium chloride+Disodium phosphate
dihydrate(P)
9150000 ml
B05ZB84
Calcium chloride dihydrate+Magnesium chloride
hexahydrate+Lactic acid+Sodium hydrogen carbonate+Sodium
chloride(P)
1020000 ml
B05ZB85 Sodium citrate+Sodium chloride(P) 2017000 ml
B05ZB86
Magnesium chloride hexahydrate+Sodium chloride+Potassium
chloride+Disodium phosphate dihydrate+Sodium hydrogen
carbonate(P)
7080000 ml
B05X I.V. SOLUTION ADDITIVES
B05XA Electrolyte solutions
B05XA01 Potassium chloride(P) 1650 g
B05XA01 Potassium chloride(P) 3601200 ml
B05XA02 Sodium hydrogen carbonate(P) 1765500 ml
B05XA03 Sodium chloride(P) 491307700 ml
B05XA05 Magnesium sulphate(P) 416900 ml
B05XA07 Calcium chloride(P) 168500 ml
B05XA14 Sodium glycerophosphate, hydrated(P) 105600 ml
B05XA80 Electrolytes(P) 137700 ml
B05XB Amino acids
B05XB01 Arginine(P) 3300 ml
B05XB02 Alanyl glutamine(P) 45000 ml
B05XC Vitamins
B05XC80 Vitamins(P) 3597,52 g
B05XC80 Vitamins(P) 183400 ml
B06 OTHER HEMATOLOGICAL AGENTS 0,0014
B06A OTHER HEMATOLOGICAL AGENTS 0,0014
B06AA Enzymes
B06AA03 Hyaluronidase(P) 90640 U
B06AB Heme products
B06AB01 Hemin(P) 40 ml
B06AB80 hemoderivate of calf blood, deproteinized(O) 100 pieces
B06AC Drugs usedin hereditary angioedema 0,0014
B06AC01 C1-inhibitor(P) 486000 U 1400 U 0,0007
B06AC02 Icatibant(P) 8,1 g 0,03 g 0,0006
B06AC04 Conestat alfa(P) 163800 U 3500 U 0,0001
C CARDIOVASCULAR SYSTEM 450,0066
C01 CARDIAC THERAPY 21,9418
C01A CARDIAC GLYCOSIDES 2,0279
C01AA Digitalis glycosides 2,0279
C01AA05 Digoxin(O) 243,6725 g 0,25 mg 2,0099
8/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C01AA05 Digoxin(P) 2,145 g 0,25 mg 0,0177
C01AA06 Lanatoside C(O) 0,18 g 0,001 g 0,0004
C01B ANTIARRHYTHMICS, CLASS I AND III 5,3353
C01BA Antiarrhythmics, class Ia <0,0001
C01BA01 Quinidine(O) 20 g 1,2 g <0,0001
C01BA13 Hydroquinidine(O) 234 g
C01BB Antiarrhythmics, class Ib 0,0235
C01BB02 Mexiletine(O) 100 g 0,8 g 0,0003
C01BB80 Aethacizin(O) 2257,5 g 0,2 g 0,0233
C01BC Antiarrhythmics, class Ic 3,4495
C01BC03 Propafenone(O) 478569 g 0,3 g 3,2895
C01BC03 Propafenone(P) 548,45 g 0,3 g 0,0038
C01BC04 Flecainide(O) 15113 g 0,2 g 0,1558
C01BC04 Flecainide(P) 39 g 0,2 g 0,0004
C01BD Antiarrhythmics, class III 1,8622
C01BD01 Amiodarone(O) 174018 g 0,2 g 1,7942
C01BD01 Amiodarone(P) 5400,75 g 0,2 g 0,0557
C01BD07 Dronedarone(O) 4800 g 0,8 g 0,0124
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES 0,6378
C01CA Adrenergic and dopaminergic agents 0,6363
C01CA01 Etilefrine(O) 1,8375 g 0,05 g 0,0001
C01CA02 Isoprenaline(P) 0,65 g 0,09 g <0,0001
C01CA03 Norepinephrine(P) 400,9 g 0,006 g 0,1378
C01CA04 Dopamine(P) 2606,6 g 0,5 g 0,0107
C01CA06 Phenylephrine(P) 211,7 g 0,004 g 0,1091
C01CA07 Dobutamine(P) 1491,25 g 0,5 g 0,0062
C01CA17 Midodrine(O) 6,45 g 0,03 g 0,0004
C01CA24 Epinephrine(I) 4,392 g
C01CA24 Epinephrine(intraoss, P) 0,05 g 0,5 mg 0,0002
C01CA24 Epinephrine(P) 80,152 g 0,5 mg 0,3306
C01CA26 Ephedrine(P) 998 g 0,05 g 0,0412
C01CE Phosphodiesterase inhibitors 0,0009
C01CE02 Milrinone(P) 21,38 g 0,05 g 0,0009
C01CX Other cardiac stimulants 0,0006
C01CX08 Levosimendan(P) 3,25 g 11 mg 0,0006
C01CX80 Ammonia(I) 1381960 ml
C01D VASODILATORS USED IN CARDIAC DISEASES 5,8804
C01DA Organic nitrates 5,8772
C01DA02 Glyceryl trinitrate(P) 206,7 g
C01DA02 Glyceryl trinitrate(SL) 507,812 g 0,0025 g 0,4189
C01DA05 Pentaerithrityl tetranitrate(O) 3 g 0,12 g 0,0001
C01DA08 Isosorbide dinitrate(O) 644 g 0,06 g 0,0221
C01DA08 Isosorbide dinitrate(SL) 236,35 g 0,02 g 0,0244
C01DA14 Isosorbide mononitrate(O) 104977,4 g 0,04 g 5,4118
C01DX Other vasodilatators used in cardiac diseases 0,0032
C01DX80 Meldonium(O) 1155 g 0,75 g 0,0032
C01DX80 Meldonium(P) 25 g 0,75 g 0,0001
C01E OTHER CARDIAC PREPARATIONS 8,0604
C01EA Prostaglandins 0,0002
C01EA01 Alprostadil(P) 0,0556 g 0,5 mg 0,0002
C01EB Other cardiac preparations 8,0602
C01EB10 Adenosine(P) 109,104 g 0,015 g 0,0150
C01EB15 Trimetazidine(O) 147291,9 g 0,04 g 7,5931
C01EB16 Ibuprofen(P) 1,16 g 0,03 g 0,0001
C01EB17 Ivabradine(O) 1774,92 g 0,01 g 0,3660
C01EB18 Ranolazine(O) 61890 g 1,5 g 0,0851
C01EB21 Regadenoson(P) 0,168 g 0,4 mg 0,0009
C01EB80 Hawthorn berry(O) 63440 ml
C02 ANTIHYPERTENSIVES 4,0447
C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING 2,4305
C02AC Imidazoline receptor agonists 2,4305
9/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C02AC01 Clonidine(O) 5,7075 g 0,45 mg 0,0262
C02AC01 Clonidine(P) 2,783 g 0,45 mg 0,0128
C02AC02 Guanfacine(O) 0,084 g 3 mg 0,0001
C02AC05 Moxonidine(O) 347,9358 g 0,3 mg 2,3916
C02C ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING 1,5733
C02CA Alpha-adrenoreceptor antagonists 1,5733
C02CA01 Prazosin(O) 3,56 g 0,005 g 0,0015
C02CA04 Doxazosin(O) 3049,028 g 0,004 g 1,5718
C02D ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON 0,0011
C02DD Nitroferricyanide derivatives 0,0011
C02DD01 Sodium nitroprusside(P) 25,47 g 0,05 g 0,0011
C02K OTHER ANTIHYPERTENSIVES 0,0399
C02KX Antihypertensives for pulmonary arterial hypertension 0,0399
C02KX01 Bosentan(O) 1505 g 0,25 g 0,0124
C02KX02 Ambrisentan(O) 48,75 g 7,5 mg 0,0134
C02KX04 Macitentan(O) 4,5 g 10 mg 0,0009
C02KX05 Riociguat(O) 28,623 g 4,5 mg 0,0131
C03 DIURETICS 27,3596
C03A LOW-CEILING DIURETICS, THIAZIDES 1,3934
C03AA Thiazides, plain 1,3934
C03AA03 Hydrochlorothiazide(O) 16893,5 g 0,025 g 1,3934
C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES 2,3642
C03BA Sulfonamides, plain 2,3642
C03BA11 Indapamide(O) 2866,35 g 2,5 mg 2,3642
C03C HIGH-CEILING DIURETICS 20,2193
C03CA Sulfonamides, plain 20,2193
C03CA01 Furosemide(O) 68271,8 g 0,04 g 3,5195
C03CA01 Furosemide(P) 6259,9 g 0,04 g 0,3227
C03CA04 Torasemide(O) 118656,9 g 0,015 g 16,3119
C03CA04 Torasemide(P) 474,1 g 0,015 g 0,0652
C03D POTASSIUM-SPARING AGENTS 3,3628
C03DA Aldosterone antagonists 3,3628
C03DA01 Spironolactone(O) 122271,25 g 0,075 g 3,3618
C03DA04 Eplerenone(O) 24,75 g 0,05 g 0,0010
C03E DIURETICS AND POTASSIUM-SPARING AGENTS IN
COMBINATION 0,0199
C03EA Low-ceiling diuretics and potassium-sparing agents 0,0199
C03EA81 Hydrochlorothiazide+Amiloride(O) 9630 pieces 1 pieces 0,0199
C04 PERIPHERAL VASODILATORS 2,6475
C04A PERIPHERAL VASODILATORS 2,6475
C04AC Nicotinic acid and derivatives 0,0006
C04AC01 Nicotinic acid(P) 54 g 0,2 g 0,0006
C04AD Purine derivatives 1,6190
C04AD02 Xantinol nicotinate(O) 81 g 0,9 g 0,0002
C04AD03 Pentoxifylline(O) 783720 g 1 g 1,6161
C04AD03 Pentoxifylline(P) 403,5 g 0,3 g 0,0028
C04AX Other peripheral vasodilators 1,0279
C04AX21 Naftidrofuryl(O) 299090 g 0,6 g 1,0279
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL
FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA82 Hydrocortisone+Cinchocaine(R) 64212 pieces
C05AA84 Fluocortolone+Lidocaine(R) 118650 pieces
C05AA84 Fluocortolone+Lidocaine(R) 244530 g
C05AE Muscle relaxants
C05AE01 Glyceryl trinitrate(R) 30 g
C05AX Other agents for treatment of hemorrhoids and anal fissures for
topical use
C05AX81 Xeroformium+Zinc sulphate+Extract of Belladonna(R) 1870 pieces
C05AX83 Yeast cell extract+Shark liver oil(R) 321900 pieces
10/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C05B ANTIVARICOSE THERAPY
C05BA Heparins or heparinoids for topical use
C05BA03 Heparin sodium(C) 7321300 g
C05BB Sclerosing agents for local injection
C05BB02 Lauromacrogol 400(P) 55,425 g
C05BB04 Sodium tetradecyl sulphate(P) 0,3 g
C05C CAPILLARY STABILIZING AGENTS
C05CA Bioflavonoids
C05CA01 Rutoside(O) 204810 pieces
C05CA03 Diosmin(O) 455430 g
C05CA04 Troxerutin(C) 3592900 g
C05CA04 Troxerutin(O) 205860 g
C05CA53 Diosmin+Hesperidine(O) 2700 pieces
C05CX Other capillary stabilizing agents
C05CX80 Vigne rouge extract(O) 54 g
C05CX81 Aescin(O) 80 pieces
C07 BETA BLOCKING AGENTS 56,9879
C07A BETA BLOCKING AGENTS 56,9871
C07AA Beta blocking agents, non-selective 1,6890
C07AA05 Propranolol(O) 49375,4 g 0,16 g 0,6363
C07AA07 Sotalol(O) 81674,4 g 0,16 g 1,0526
C07AB Beta blocking agents, selective 54,5936
C07AB02 Metoprolol(O) 1991991,45 g 0,15 g 27,3841
C07AB02 Metoprolol(P) 106,55 g 0,15 g 0,0015
C07AB03 Atenolol(O) 18654,75 g 0,075 g 0,5129
C07AB07 Bisoprolol(O) 17943,6 g 0,01 g 3,7001
C07AB09 Esmolol(P) 0,5 g 2,5 g <0,0001
C07AB12 Nebivolol(O) 55757,03 g 0,005 g 22,9950
C07AG Alpha and beta blocking agents 0,7046
C07AG01 Labetalol(O) 27670 g 0,6 g 0,0951
C07AG01 Labetalol(P) 1475,5 g 0,6 g 0,0051
C07AG02 Carvedilol(O) 10992 g 0,0375 g 0,6044
C07B BETA BLOCKING AGENTS AND THIAZIDES 0,0007
C07BB Beta blocking agents, selective, and thiazides 0,0007
C07BB07 Bisoprolol+Hydrochlorothiazide(O) 360 pieces 1 pieces 0,0007
C08 CALCIUM CHANNEL BLOCKERS 46,4845
C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY
VASCULAR EFFECTS 45,0090
C08CA Dihydropyridine derivatives 45,0090
C08CA01 Amlodipine(O) 63552,75 g 0,005 g 26,2100
C08CA02 Felodipine(O) 6126,975 g 0,005 g 2,5268
C08CA05 Nifedipine(O) 14290,72 g 0,03 g 0,9823
C08CA06 Nimodipine(O) 402 g 0,3 g 0,0028
C08CA06 Nimodipine(P) 3,65 g 0,05 g 0,0002
C08CA08 Nitrendipine(O) 42779,64 g 0,02 g 4,4107
C08CA09 Lacidipine(O) 6126,624 g 0,004 g 3,1584
C08CA13 Lercanidipine(O) 37427,4 g 0,01 g 7,7178
C08D SELECTIVE CALCIUM CHANNEL BLOCKERS WITH DIRECT
CARDIAC EFFECTS 1,4755
C08DA Phenylalkylamine derivatives 1,3680
C08DA01 Verapamil(O) 159208 g 0,24 g 1,3679
C08DA01 Verapamil(P) 13,85 g 0,24 g 0,0001
C08DB Benzothiazepine derivatives 0,1075
C08DB01 Diltiazem(O) 12508,2 g 0,24 g 0,1075
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM 210,3541
C09A ACE INHIBITORS, PLAIN 75,8991
C09AA ACE inhibitors, plain 75,8991
C09AA01 Captopril(O) 923,5 g 0,05 g 0,0381
C09AA02 Enalapril(O) 40891,23 g 0,01 g 8,4321
C09AA02 Enalapril(P) 9,5688 g 0,01 g 0,0020
C09AA03 Lisinopril(O) 5,04 g 0,01 g 0,0010
11/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C09AA04 Perindopril(O) 14762,7 g 0,004 g 7,6104
C09AA05 Ramipril(O) 66657,77 g 2,5 mg 54,9811
C09AA09 Fosinopril(O) 34269,2 g 0,015 g 4,7110
C09AA10 Trandolapril(O) 119,616 g 0,002 g 0,1233
C09B ACE INHIBITORS, COMBINATIONS 56,7495
C09BA ACE inhibitors and diuretics 29,2415
C09BA02 Enalapril+Hydrochlorothiazide(O) 2792120 pieces 1 pieces 5,7575
C09BA04 Perindopril+Indapamide(O) 9573390 pieces 1 pieces 19,7410
C09BA05 Ramipril+Hydrochlorothiazide(O) 1235530 pieces 1 pieces 2,5477
C09BA09 Fosinopril+Hydrochlorothiazide(O) 579612 pieces 1 pieces 1,1952
C09BB ACE inhibitors and calcium channel blockers 12,8524
C09BB03 Lisinopril+Amlodipine(O) 847020 pieces 1 pieces 1,7466
C09BB04 Perindopril+Amlodipine(O) 4185870 pieces 1 pieces 8,6315
C09BB07 Ramipril+Amlodipine(O) 903030 pieces 1 pieces 1,8621
C09BB10 Trandolapril+Verapamil(O) 296856 pieces 1 pieces 0,6121
C09BX ACE inhibitors, other combinations 14,6556
C09BX01 Perindopril+Amlodipine+Indapamide(O) 7107240 pieces 1 pieces 14,6556
C09C ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS), PLAIN 43,2749
C09CA Angiotensin II receptor blockers (ARBs), plain 43,2749
C09CA01 Losartan(O) 85044 g 0,05 g 3,5073
C09CA02 Eprosartan(O) 840 g 0,6 g 0,0029
C09CA03 Valsartan(O) 170325,12 g 0,08 g 4,3903
C09CA06 Candesartan(O) 41969,312 g 0,008 g 10,8179
C09CA07 Telmisartan(O) 413416,96 g 0,04 g 21,3123
C09CA08 Olmesartan medoxomil(O) 31464,44 g 0,02 g 3,2441
C09D ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS),
COMBINATIONS 34,4306
C09DA Angiotensin II receptor blockers (ARBs) and diuretics 15,8037
C09DA01 Losartan+Hydrochlorothiazide(O) 790330 pieces 1 pieces 1,6297
C09DA03 Valsartan+Hydrochlorothiazide(O) 899388 pieces 1 pieces 1,8546
C09DA06 Candesartan+Hydrochlorothiazide(O) 1151244 pieces 1 pieces 2,3739
C09DA07 Telmisartan+Hydrochlorothiazide(O) 4563908 pieces 1 pieces 9,4111
C09DA08 Olmesartan medoxomil+Hydrochlorothiazide(O) 259140 pieces 1 pieces 0,5344
C09DB Angiotensin II receptor blockers (ARBs) and calcium channel
blockers 13,5511
C09DB01 Valsartan+Amlodipine(O) 216428 pieces 1 pieces 0,4463
C09DB02 Olmesartan medoxomil+Amlodipine(O) 3087112 pieces 1 pieces 6,3658
C09DB04 Telmisartan+Amlodipine(O) 3201632 pieces 1 pieces 6,6020
C09DB07 Candesartan+Amlodipine(O) 66416 pieces 1 pieces 0,1370
C09DX Angiotensin II receptor blockers (ARBs), other combinations 5,0759
C09DX01 Valsartan+Amlodipine+Hydrochlorothiazide(O) 2352 pieces 1 pieces 0,0048
C09DX03 Olmesartan medoxomil+Amlodipine+Hydrochlorothiazide(O) 2176244 pieces 1 pieces 4,4876
C09DX04 Valsartan+Sacubitril(O) 282940 pieces 1 pieces 0,5834
C10 LIPID MODIFYING AGENTS 80,1865
C10A LIPID MODIFYING AGENTS, PLAIN 77,9115
C10AA HMG CoA reductase inhibitors 76,7312
C10AA01 Simvastatin(O) 67853,92 g 0,03 g 4,6640
C10AA03 Pravastatin(O) 4074 g 0,03 g 0,2800
C10AA04 Fluvastatin(O) 15836,8 g 0,06 g 0,5443
C10AA05 Atorvastatin(O) 295816,2 g 0,02 g 30,4997
C10AA07 Rosuvastatin(O) 197584,23 g 0,01 g 40,7432
C10AB Fibrates 0,6614
C10AB05 Fenofibrate(O) 64152 g 0,2 g 0,6614
C10AC Bile acid sequestrants 0,0012
C10AC01 Colestyramine(O) 7800 g 14 g 0,0011
C10AC02 Colestipol(O) 250 g 20 g <0,0001
C10AX Other lipid modifying agents 0,5177
C10AX09 Ezetimibe(O) 2427,32 g 0,01 g 0,5005
12/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C10AX13 Evolocumab(P) 58,94 g 10 mg 0,0122
C10AX14 Alirocumab(P) 13,2 g 5,4 mg 0,0050
C10AX80 Omega-3-acid ethyl esters 90(O) 188944 pieces
C10B LIPID MODIFYING AGENTS, COMBINATIONS 2,2750
C10BA Combinations of various lipid modifying agents 1,5405
C10BA05 Atorvastatin+Ezetimibe(O) 18660 pieces 1 pieces 0,0385
C10BA06 Rosuvastatin+Ezetimibe(O) 728400 pieces 1 pieces 1,5020
C10BX Lipid modifying agents in combination with other drugs 0,7345
C10BX03 Atorvastatin+Amlodipine(O) 83250 pieces 1 pieces 0,1717
C10BX11 Atorvastatin+Amlodipine+Perindopril(O) 213330 pieces 1 pieces 0,4399
C10BX13 Rosuvastatin+Perindopril+Indapamide(O) 37800 pieces 1 pieces 0,0779
C10BX15 Atorvastatin+Perindopril(O) 21840 pieces 1 pieces 0,0450
D DERMATOLOGICALS 1,7338
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE 1,0595
D01A ANTIFUNGALS FOR TOPICAL USE
D01AC Imidazole and triazole derivatives
D01AC01 Clotrimazole(C) 569708,6 g
D01AC05 Isoconazole(C) 261742,01 g
D01AC08 Ketoconazole(C) 723219 g
D01AC08 Ketoconazole(C) 773160 ml
D01AC80 Isoconazole+Diflucortolone(C) 435645 g
D01AC81 Clotrimazole+Hexamidine(C) 145020 g
D01AE Other antifungals for topical use
D01AE14 Ciclopirox(C) 1762,2 ml
D01AE15 Terbinafine(C) 586469 g
D01AE16 Amorolfine(C) 29580 ml
D01AE22 Naftifine(C) 182360 ml
D01AE22 Naftifine(C) 233895 g
D01B ANTIFUNGALS FOR SYSTEMIC USE 1,0595
D01BA Antifungals for systemic use 1,0595
D01BA01 Griseofulvin(O) 977,5 g 0,5 g 0,0040
D01BA02 Terbinafine(O) 127966 g 0,25 g 1,0555
D02 EMOLLIENTS AND PROTECTIVES
D02A EMOLLIENTS AND PROTECTIVES
D02AB Zinc products
D02AB80 Zinc oxide(C) 408780 g
D02AE Carbamide products
D02AE01 Urea(C) 78150 g
D02AF Salicylic acid preparations
D02AF81 Salicylic acid+Lactic acid(C) 2009,01 g
D02B PROTECTIVES AGAINST UV-RADIATION
D02BA Protectives against UV-radiation for topical use
D02BA01 4-Aminobenzoic acid(O) 9720 g
D03 PREPARATIONS FOR TREATMENT OF WOUNDS AND
ULCERS
D03A CICATRIZANTS
D03AX Other cicatrizants
D03AX03 Dexpanthenol(C) 3814745 g
D03AX81 Heparin sodium+Allantoin+Extract of Cepae(C) 115500 g
D03AX83 Dexpanthenol+Chlorhexidine(C) 1914240 g
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS,
ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS,
ETC.
D04AA Antihistamines for topical use
D04AA09 Chloropyramine(P) 10 g
D05 ANTIPSORIATICS 0,0534
D05A ANTIPSORIATICS FOR TOPICAL USE
D05AA Tars
D05AA85 Coal tar+Salicylic acid(C) 588000 ml
D05AC Antracen derivatives
13/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D05AC01 Dithranol(C) 4550 g
D05AX Other antipsoriatics for topical use
D05AX02 Calcipotriol(C) 210 g
D05AX80 Calcipotriol+Betamethasone(C) 853350 g
D05B ANTIPSORIATICS FOR SYSTEMIC USE 0,0534
D05BB Retinoids for treatment of psoriasis 0,0534
D05BB02 Acitretin(O) 906,3 g 0,035 g 0,0534
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR
DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE
D06AX Other antibiotics for topical use
D06AX01 Fusidic acid(C) 210705 g
D06AX09 Mupirocin(C) 2310 g
D06AX80 Bacitracin+Neomycin(C) 155540 g
D06AX84 Chloramphenicol+Methyluracil(C) 4000 g
D06B CHEMOTHERAPEUTICS FOR TOPICAL USE
D06BA Sulfonamides
D06BA01 Silver sulfadiazine(C) 1533900 g
D06BB Antivirals
D06BB03 Aciclovir(C) 199734 g
D06BB04 Podophyllotoxin(C) 1253 ml
D06BB06 Penciclovir(C) 28 g
D06BB10 Imiquimod(C) 6467 g
D06BB81 Aciclovir+Hydrocortisone(C) 31168 g
D06BX Other chemotherapeutics
D06BX01 Metronidazole (C) 123150 g
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AA Corticosteroids, weak (group I)
D07AA02 Hydrocortisone(C) 590660 g
D07AC Corticosteroids, potent (group III)
D07AC01 Betamethasone(C) 139380 g
D07AC04 Fluocinolone acetonide(C) 435 g
D07AC13 Mometasone(C) 332200 ml
D07AC13 Mometasone(C) 1176620 g
D07AC14 Methylprednisolone aceponate(C) 587385 g
D07AC17 Fluticasone(C) 51435 g
D07AD Corticosteroids, very potent (group IV)
D07AD01 Clobetasol(C) 89625 ml
D07AD01 Clobetasol(C) 935100 g
D07B CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS
D07BA Corticosteroids, weak, combinations with antiseptics
D07BA80 Hydrocortisone+Chlorhexidine(C) 350700 g
D07BC Corticosteroids, potent, combinations with antiseptics
D07BC80 Betamethasone+Salicylic acid(C) 17435 g
D07BC80 Betamethasone+Salicylic acid(C) 937650 ml
D07C CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
D07CA Corticosteroids, weak, combinations with antibiotics
D07CA83 Hydrocortisone+Fusidic acid(C) 77550 g
D07CC Corticosteroids, potent, combinations with antibiotics
D07CC80 Betamethasone+Fusidic acid(C) 570150 g
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XA Corticosteroids, weak, other combinations
D07XA81 Prednisolone+Salicylic acid(C) 229500 ml
D07XC Corticosteroids, potent, other combinations
D07XC03 Mometasone+Salicylic acid(C) 225,6 g
D08 ANTISEPTICS AND DISINFECTANTS
D08A ANTISEPTICS AND DISINFECTANTS
14/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D08AG Iodine products
D08AG02 Povidone, iodinated(C) 1095050 ml
D08AG02 Povidone, iodinated(C) 3596810 g
D08AG03 Iodine(C) 921240 ml
D08AJ Quaternary ammonium compounds
D08AJ81 Octenidine+Phenoxyethanol(C) 11705950 ml
D08AX Other antiseptics and disinfectants
D08AX82 Tar+Castor oil+Xeroformium(C) 7350 g
D08AX83 Brilliant Green(C) 268060 ml
D10 ANTI-ACNE PREPARATIONS 0,5408
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AD Retinoids for topical use in acne
D10AD01 Tretinoin(C) 26850 g
D10AD03 Adapalene(C) 109650 g
D10AD80 Adapalene+Benzoyl peroxide(C) 95220 g
D10AD81 Tretinoin+Erythromycin(C) 28110 g
D10AF Antiinfectives for treatment of acne
D10AF02 Erythromycin(C) 229900 ml
D10AF81 Clindamycin+Benzoyl peroxide(C) 304875 g
D10AF82 Clindamycin+Tretinoin(C) 128820 g
D10AX Other anti-acne preparations for topical use
D10AX03 Azelaic acid(C) 317250 g
D10B ANTI-ACNE PREPARATIONS FOR SYSTEMIC USE 0,5408
D10BA Retinoids for treatment of acne 0,5408
D10BA01 Isotretinoin(O) 7868,4 g 0,03 g 0,5408
D11 OTHER DERMATOLOGICAL PREPARATIONS 0,0800
D11A OTHER DERMATOLOGICAL PREPARATIONS 0,0800
D11AH Agents for dermatitis, excluding corticosteroids 0,0184
D11AH01 Tacrolimus(C) 66390 g
D11AH02 Pimecrolimus(C) 222240 g
D11AH05 Dupilumab(P) 190,8 g 21,4 mg 0,0184
D11AX Other dermatologicals 0,0617
D11AX01 Minoxidil(C) 166680 ml
D11AX10 Finasteride(O) 29,904 g 0,001 g 0,0617
D11AX16 Eflornithine(C) 870 g
D11AX21 Brimonidine(C) 120 g
D11AX22 Ivermectin(C) 73140 g
D11AX24 Deoxycholic acid(P) 0,08 g
G GENITO URINARY SYSTEM AND SEX HORMONES 56,3570
G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS 0,8710
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL.
COMBINATIONS WITH CORTICOSTEROIDS 0,8710
G01AA Antibiotics 0,1081
G01AA01 Nystatin(O) 600000 U
G01AA10 Clindamycin(V) 5243,5 g 0,1 g 0,1081
G01AA80 Nystatin+Neomycin+Polymyxin B(V) 48 pieces
G01AC Quinoline derivatives 0,0433
G01AC05 Dequalinium(V) 419,64 g 20 mg 0,0433
G01AF Imidazole derivatives 0,7196
G01AF01 Metronidazole (V) 12554 g 0,5 g 0,0518
G01AF02 Clotrimazole(V) 27767,8 g 0,1 g 0,5726
G01AF05 Econazole(V) 4617,6 g 0,1 g 0,0952
G02 OTHER GYNECOLOGICALS 4,1361
G02A UTEROTONICS 0,0959
G02AB Ergot alkaloids 0,0020
G02AB01 Methylergometrine(P) 0,1944 g 0,2 mg 0,0020
G02AD Prostaglandins 0,0938
G02AD02 Dinoprostone(P) 0,14 g
G02AD02 Dinoprostone(V) 1,8499 g 0,5 mg 0,0076
G02AD06 Misoprostol(O) 8,3624 g 0,2 mg 0,0862
G02B CONTRACEPTIVES FOR TOPICAL USE 2,5451
15/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G02BA Intrauterine contraceptives 0,0176
G02BA03 Levonorgestrel(V) 8520 pieces 1 pieces 0,0176
G02BB Intravaginal contraceptives 2,5275
G02BB01 Etonogestrel+Ethinylestradiol(V) 42954 pieces 0,036 pieces 2,4604
G02BB81 Benzalkonium chloride(V) 32560 pieces 1 pieces 0,0671
G02BB81 Benzalkonium chloride(V) 40680 g
G02C OTHER GYNECOLOGICALS 1,4951
G02CA Sympathomimetics, labour repressants
G02CA80 Hexoprenaline(P) 0,0164 g
G02CB Prolactine inhibitors 0,1403
G02CB01 Bromocriptine(O) 276 g 0,005 g 0,1138
G02CB03 Cabergoline(O) 6,42 g 0,5 mg 0,0265
G02CX Other gynecologicals 1,3548
G02CX01 Atosiban(P) 0,5962 g 0,165 g <0,0001
G02CX03 Agni casti fructus(O) 378870 pieces 1 pieces 0,7813
G02CX04 Cimicifugae rhizoma(O) 556290 pieces 2 pieces 0,5736
G03 SEX HORMONES AND MODULATORS OF THE GENITAL
SYSTEM 30,7035
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE 24,3650
G03AA Progestogens and estrogens, fixed combinations 19,6630
G03AA07 Levonorgestrel+Ethinylestradiol(O) 205436 pieces 1 pieces 0,4236
G03AA09 Desogestrel+Ethinylestradiol(O) 423549 pieces 0,75 pieces 1,1645
G03AA10 Gestodene+Ethinylestradiol(O) 9324 pieces 1 pieces 0,0192
G03AA10 Gestodene+Ethinylestradiol(O) 2165163 pieces 0,75 pieces 5,9530
G03AA12 Drospirenone+Ethinylestradiol(O) 1203552 pieces 1 pieces 2,4818
G03AA12 Drospirenone+Ethinylestradiol(O) 1732962 pieces 0,75 pieces 4,7646
G03AA13 Norelgestromin+Ethinylestradiol(TD) 91479 pieces 0,107 pieces 1,7630
G03AA15 Chlormadinone+Ethinylestradiol(O) 155673 pieces 0,75 pieces 0,4280
G03AA16 Dienogest+Ethinylestradiol(O) 368004 pieces 1 pieces 0,7588
G03AA16 Dienogest+Ethinylestradiol(O) 693399 pieces 0,75 pieces 1,9064
G03AB Progestogens and estrogens, sequential preparations 0,1742
G03AB05 Desogestrel+Ethinylestradiol(O) 3432 pieces 0,75 pieces 0,0094
G03AB08 Dienogest+Estradiol valerate(O) 79884 pieces 1 pieces 0,1647
G03AC Progestogens 4,4487
G03AC08 Etonogestrel(P) 56,372 g 68 mcg 1,7095
G03AC09 Desogestrel(O) 1328376 pieces 1 pieces 2,7392
G03AD Emergency contraceptives 0,0792
G03AD01 Levonorgestrel(O) 56,0355 g 1,5 mg 0,0770
G03AD02 Ulipristal(O) 30,96 g 0,03 g 0,0021
G03B ANDROGENS 0,2331
G03BA 3-oxoandrosten (4) derivatives 0,2331
G03BA03 Testosterone(C) 6 g 0,05 g 0,0002
G03BA03 Testosterone(O) 14,4 g 0,12 g 0,0002
G03BA03 Testosterone(P) 2021,5 g 0,018 g 0,2316
G03BA03 Testosterone(TD) 25,76 g 0,05 g 0,0011
G03C ESTROGENS 1,4872
G03CA Natural and semisynthetic estrogens, plain 1,4772
G03CA03 Estradiol(C, V) 74225 g
G03CA03 Estradiol(O) 794,332 g 2 mg 0,8190
G03CA03 Estradiol(TD) 0,021 g 0,05 mg 0,0009
G03CA03 Estradiol(TD) 35,5572 g 1,53 mg 0,0479
G03CA03 Estradiol(TD) 75,012 g 1 mg 0,1547
G03CA03 Estradiol(V) 3,3127 g 0,025 mg 0,2732
G03CA04 Estriol(V) 17,6025 g 0,2 mg 0,1815
G03CA80 Estradiol+Prednisolone(C) 66250 g
G03CX Other estrogens 0,0100
G03CX01 Tibolone(O) 12,11 g 2,5 mg 0,0100
G03D PROGESTOGENS 1,7406
G03DA Pregnen (4) derivatives 1,0147
G03DA02 Medroxyprogesterone(O) 57,6 g 0,005 g 0,0238
G03DA02 Medroxyprogesterone(P) 250,485 g 0,007 g 0,0738
16/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G03DA04 Progesterone(O) 18807 g 0,3 g 0,1293
G03DA04 Progesterone(P) 218,7812 g 0,005 g 0,0902
G03DA04 Progesterone(V) 30450,45 g 0,09 g 0,6977
G03DB Pregnadien derivatives 0,7259
G03DB01 Dydrogesterone(O) 2592,2 g 0,01 g 0,5345
G03DB08 Dienogest(O) 185,64 g 2 mg 0,1914
G03F PROGESTOGENS AND ESTROGENS IN COMBINATION 2,1009
G03FA Progestogens and estrogens, fixed combinations 1,6631
G03FA01 Norethisterone+Estradiol(O) 512568 pieces 1 pieces 1,0570
G03FA14 Dydrogesterone+Estradiol(O) 127316 pieces 1 pieces 0,2625
G03FA17 Drospirenone+Estradiol(O) 166656 pieces 1 pieces 0,3437
G03FB Progestogens and estrogens, sequential preparations 0,4378
G03FB05 Norethisterone+Estradiol(O) 156464 pieces 1 pieces 0,3226
G03FB08 Dydrogesterone+Estradiol(O) 55832 pieces 1 pieces 0,1151
G03G GONADOTROPINS AND OTHER OVULATION STIMULANTS 0,3707
G03GA Gonadotropins 0,1481
G03GA01 Chorionic gonadotrophin(P) 45000 U 250 U 0,0004
G03GA05 Follitropin alfa(P) 4505175 U 75 U 0,1239
G03GA07 Lutropin alfa(P) 564975 U 75 U 0,0155
G03GA08 Choriogonadotropin alfa(P) 0,7398 g 0,25 mg 0,0061
G03GA30 Follitropin alfa+Lutropin alfa(P) 1075 doses 1 doses 0,0022
G03GB Ovulation stimulants, synthetic 0,2226
G03GB02 Clomifene(O) 971,5 g 0,009 g 0,2226
G03H ANTIANDROGENS 0,3996
G03HA Antiandrogens, plain 0,0810
G03HA01 Cyproterone(O) 3927,5 g 0,1 g 0,0810
G03HB Antiandrogens and estrogens 0,3187
G03HB01 Cyproterone+Estrogen(O) 115899 pieces 0,75 pieces 0,3187
G03X OTHER SEX HORMONES AND MODULATORS OF THE
GENITAL SYSTEM 0,0063
G03XA Antigonadotropins and similar agents 0,0006
G03XA01 Danazol(O) 180 g 0,6 g 0,0006
G03XB Progesterone receptor modulators 0,0057
G03XB01 Mifepristone(O) 794,4 g 0,6 g 0,0027
G03XB02 Ulipristal(O) 7,14 g 5 mg 0,0029
G04 UROLOGICALS 20,6464
G04B UROLOGICALS 3,4825
G04BC Urinary concrement solvents
G04BC81 Sodium citrate+Potassium hydrogen carbonate+Citric acid(O) 650 pieces
G04BD Drugs for urinary frequency and incontinence 1,9961
G04BD04 Oxybutynin(O) 4611,3 g 0,015 g 0,6339
G04BD06 Propiverine(O) 8,82 g 0,03 g 0,0006
G04BD07 Tolterodine(O) 481,6 g 0,004 g 0,2483
G04BD08 Solifenacin(O) 827,1 g 0,005 g 0,3411
G04BD09 Trospium chloride(O) 3661,2 g 0,04 g 0,1887
G04BD12 Mirabegron(O) 14146,5 g 50 mg 0,5834
G04BE Drugs used in erectile dysfunction 1,4762
G04BE01 Alprostadil(P) 0,0455 g 0,02 mg 0,0047
G04BE01 Alprostadil(urethral) 0,144 g 0,25 mg 0,0012
G04BE03 Sildenafil(O) 25530,8 g 0,05 g 1,0529
G04BE08 Tadalafil(O) 1726,52 g 0,01 g 0,3560
G04BE09 Vardenafil(O) 47,12 g 0,01 g 0,0097
G04BE10 Avanafil(O) 2506,8 g 0,1 g 0,0517
G04BX Other urologicals 0,0102
G04BX14 Dapoxetin(O) 147,96 g 0,03 g 0,0102
G04BX80 Centaury+Lovage root+Rosemary leaf(O) 1031520 pieces
G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY 17,1640
17/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G04CA Alpha-adrenoreceptor antagonists 14,2023
G04CA01 Alfuzosin(O) 8265,3 g 7,5 mg 2,2725
G04CA02 Tamsulosin(O) 1543,772 g 0,4 mg 7,9584
G04CA04 Silodosin(O) 747,32 g 8 mg 0,1926
G04CA52 Tamsulosin+Dutasteride(O) 1832520 pieces 1 pieces 3,7788
G04CB Testosterone-5-alpha reductase inhibitors 0,5732
G04CB01 Finasteride(O) 393,67 g 0,005 g 0,1624
G04CB02 Dutasteride(O) 99,63 g 0,5 mg 0,4109
G04CX Other drugs used in benign prostatic hypertrophy 2,3884
G04CX02 Sabalis serrulatae fructus(O) 370646,4 g 0,32 g 2,3884
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX
HORMONES AND INSULINS 30,5130
H01 PITUITARY AND HYPOTHALAMIC HORMONES AND
ANALOGUES 0,4578
H01A ANTERIOR PITUITARY LOBE HORMONES AND
ANALOGUES 0,1824
H01AA ACTH 0,0002
H01AA02 Tetracosactide(P) 0,0293 g 0,25 mg 0,0002
H01AB Thyrotropin 0,0004
H01AB01 Thyrotropin alfa(P) 0,1548 g 0,9 mg 0,0004
H01AC Somatropin and somatropin agonists 0,1621
H01AC01 Somatropin(P) 157203,9153 U 2 U 0,1621
H01AX Other anterior pituitary lobe hormones and analogues 0,0197
H01AX01 Pegvisomant(P) 95,4 g 0,01 g 0,0197
H01B POSTERIOR PITUITARY LOBE HORMONES 0,1423
H01BA Vasopressin and analogues 0,0909
H01BA01 Argipressin(P) 24000 U 40 U 0,0012
H01BA02 Desmopressin(N) 0,0306 g 0,025 mg 0,0025
H01BA02 Desmopressin(P) 0,0218 g 0,004 mg 0,0112
H01BA02 Desmopressin(SL) 8,8398 g 0,24 mg 0,0760
H01BB Oxytocin and analogues 0,0514
H01BB01 Demoxytocin(O) 970000 U 100 U 0,0200
H01BB02 Oxytocin(P) 216600 U 15 U 0,0298
H01BB03 Carbetocin(P) 0,078 g 0,1 mg 0,0016
H01C HYPOTHALAMIC HORMONES 0,1331
H01CA Gonadotropin-releasing hormones
H01CA01 Gonadorelin(P) 0,0042 g
H01CB Somatostatin and analogues 0,1142
H01CB02 Octreotide(P) 12,359 g 0,7 mg 0,0364
H01CB03 Lanreotide(P) 101,19 g 3 mg 0,0696
H01CB05 Pasireotide(P) 4,79 g 1,2 mg 0,0082
H01CC Anti-gonadotropin-releasing hormones 0,0189
H01CC02 Cetrorelix(P) 2,2953 g 0,25 mg 0,0189
H02 CORTICOSTEROIDS FOR SYSTEMIC USE 8,9526
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN 8,9476
H02AA Mineralocorticoids 0,1683
H02AA02 Fludrocortisone(O) 8,16 g 0,1 mg 0,1683
H02AB Glucocorticoids 8,7794
H02AB01 Betamethasone(P) 13,968 g 1,5 mg 0,0192
H02AB02 Dexamethasone(O) 852,84 g 1,5 mg 1,1724
H02AB02 Dexamethasone(P) 1039,8 g 1,5 mg 1,4294
H02AB04 Methylprednisolone(O) 7298,8 g 7,5 mg 2,0067
H02AB04 Methylprednisolone(P) 4466,85 g 0,02 g 0,4605
H02AB06 Prednisolone(O) 12583 g 0,01 g 2,5947
H02AB06 Prednisolone(P) 2013,65 g 0,01 g 0,4152
H02AB08 Triamcinolone(O) 10 g 7,5 mg 0,0027
H02AB08 Triamcinolone(P) 1447,6 g 7,5 mg 0,3980
H02AB09 Hydrocortisone(O) 3493,05 g 0,03 g 0,2401
H02AB09 Hydrocortisone(P) 585,8 g 0,03 g 0,0403
H02B CORTICOSTEROIDS FOR SYSTEMIC USE, COMBINATIONS 0,0050
18/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
H02BX Corticosteroids for systemic use, combinations 0,0050
H02BX80 Hydrocortisone+Lidocaine(P) 72,125 g 0,03 g 0,0050
H03 THYROID THERAPY 21,0621
H03A THYROID PREPARATIONS 19,9294
H03AA Thyroid hormones 19,9294
H03AA01 Levothyroxine sodium(O) 1449,575 g 0,15 mg 19,9275
H03AA02 Liothyronine(O) 0,0553 g 0,06 mg 0,0019
H03AA03 Levothyroxine sodium+Liothyronine(O) 500 pieces
H03B ANTITHYROID PREPARATIONS 1,1327
H03BA Thiouracils 0,0920
H03BA02 Propylthiouracil(O) 4463,5 g 0,1 g 0,0920
H03BB Sulfur-containing imidazole derivatives 1,0407
H03BB02 Thiamazole(O) 5046,75 g 0,01 g 1,0407
H03BC Perchlorates
H03BC02 Sodium perchlorate(O) 48 g
H04 PANCREATIC HORMONES 0,0011
H04A GLYCOGENOLYTIC HORMONES 0,0011
H04AA Glycogenolytic hormones 0,0011
H04AA01 Glucagon(P) 0,54 g 0,001 g 0,0011
H05 CALCIUM HOMEOSTASIS 0,0393
H05B ANTI-PARATHYROID AGENTS 0,0393
H05BX Other anti-parathyroid agents 0,0393
H05BX01 Cinacalcet(O) 931,56 g 0,06 g 0,0320
H05BX02 Paricalcitol(O) 0,0071 g 2 mcg 0,0073
J ANTIINFECTIVES FOR SYSTEMIC USE 17,7152
J01 ANTIBACTERIALS FOR SYSTEMIC USE 10,6478
J01A TETRACYCLINES 1,3901
J01AA Tetracyclines 1,3901
J01AA02 Doxycycline(O) 67380,24 g 0,1 g 1,3894
J01AA07 Tetracycline(O) 7 g 1 g <0,0001
J01AA12 Tigecycline(P) 31 g 0,1 g 0,0006
J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS 3,7574
J01CA Penicillins with extended spectrum 1,3216
J01CA01 Ampicillin(P) 20900 g 6 g 0,0072
J01CA04 Amoxicillin(O) 956108 g 1,5 g 1,3144
J01CA04 Amoxicillin(P) 10 g 3 g <0,0001
J01CE Beta-lactamase sensitive penicillins 0,1220
J01CE01 Benzylpenicillin(P) 27540 g 3,6 g 0,0158
J01CE02 Phenoxymethylpenicillin(O) 102289,2 g 2 g 0,1055
J01CE08 Benzathine benzylpenicillin(P) 1337,4 g 3,6 g 0,0008
J01CE80 Benzathine benzylpenicillin+Procaine benzylpenicillin(P) 15,3 g 3,6 g <0,0001
J01CF Beta-lactamase resistant penicillins 0,0978
J01CF04 Oxacillin(P) 94584 g 2 g 0,0975
J01CF05 Flucloxacillin(O) 240 g 2 g 0,0002
J01CR Combinations of penicillins, incl. beta-lactamase inhibitors 2,2161
J01CR01 Ampicillin+Sulbactam(P) 70434 g 6 g 0,0242
J01CR02 Amoxicillin+Clavulanic acid(O) 1352010,1 g 1,5 g 1,8586
J01CR02 Amoxicillin+Clavulanic acid(P) 306478 g 3 g 0,2107
J01CR04 Sultamicillin(O) 50013 g 1,5 g 0,0688
J01CR05 Piperacillin+Tazobactam(P) 365628 g 14 g 0,0539
J01D OTHER BETA-LACTAM ANTIBACTERIALS 1,5344
J01DB First-generation cephalosporins 0,2135
J01DB01 Cefalexin(O) 96 g 2 g 0,0001
J01DB04 Cefazolin(P) 109130 g 3 g 0,0750
J01DB05 Cefadroxil(O) 134219 g 2 g 0,1384
J01DC Second-generation cephalosporins 1,1693
J01DC01 Cefoxitin(P) 13850 g 6 g 0,0048
J01DC02 Cefuroxime(O) 229047,5 g 0,5 g 0,9446
J01DC02 Cefuroxime(P) 263572,5 g 3 g 0,1812
J01DC10 Cefprozil(O) 18805,5 g 1 g 0,0388
19/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J01DD Third-generation cephalosporins 0,0590
J01DD01 Cefotaxime(P) 50730 g 4 g 0,0262
J01DD02 Ceftazidime(P) 17860 g 4 g 0,0092
J01DD04 Ceftriaxone(P) 21570 g 2 g 0,0222
J01DD81 Ceftazidime+Avibactam(P) 3980 g 6 g 0,0014
J01DE Fourth-generation cephalosporins 0,0143
J01DE01 Cefepime(P) 27710 g 4 g 0,0143
J01DH Carbapenems 0,0782
J01DH02 Meropenem(P) 57741 g 3 g 0,0397
J01DH03 Ertapenem(P) 11652 g 1 g 0,0240
J01DH51 Imipenem+Cilastatin(P) 14055 g 2 g 0,0145
J01DI Other cephalosporins and penems 0,0002
J01DI54 Ceftolozane+Tazobactam(P) 240 g 3 g 0,0002
J01E SULFONAMIDES AND TRIMETHOPRIM 0,3386
J01EA Trimethoprim and derivatives 0,0418
J01EA01 Trimethoprim(O) 8106 g 0,4 g 0,0418
J01EE Combinations of sulfonamides and trimethoprim, incl.
derivatives 0,2968
J01EE01 Sulfamethoxazole+Trimethoprim(O) 248400 pieces 2 pieces 0,2561
J01EE01 Sulfamethoxazole+Trimethoprim(O) 674100 ml 40 ml 0,0348
J01EE01 Sulfamethoxazole+Trimethoprim(P) 57530 ml 20 ml 0,0059
J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS 1,9702
J01FA Macrolides 1,8016
J01FA01 Erythromycin(P) 400 g 1 g 0,0008
J01FA09 Clarithromycin(O) 309700 g 0,5 g 1,2772
J01FA09 Clarithromycin(P) 3356 g 1 g 0,0069
J01FA10 Azithromycin(O) 75143,5 g 0,3 g 0,5165
J01FA10 Azithromycin(P) 17,5 g 0,5 g 0,0001
J01FF Lincosamides 0,1686
J01FF01 Clindamycin(O) 90580,8 g 1,2 g 0,1557
J01FF01 Clindamycin(P) 11316 g 1,8 g 0,0130
J01G AMINOGLYCOSIDE ANTIBACTERIALS 0,0240
J01GB Other aminoglycosides 0,0240
J01GB01 Tobramycin(I) 50,176 g 0,112 g 0,0009
J01GB01 Tobramycin(I) 268,8 g 0,3 g 0,0018
J01GB01 Tobramycin(P) 48 g 0,24 g 0,0004
J01GB03 Gentamicin(P) 1439,2 g 0,24 g 0,0124
J01GB04 Kanamycin(P) 500 g 1 g 0,0010
J01GB06 Amikacin(P) 3610 g 1 g 0,0074
J01M QUINOLONE ANTIBACTERIALS 0,8827
J01MA Fluoroquinolones 0,8827
J01MA01 Ofloxacin(O) 3198 g 0,4 g 0,0165
J01MA02 Ciprofloxacin(O) 287275 g 1 g 0,5924
J01MA02 Ciprofloxacin(P) 12342,5 g 0,8 g 0,0318
J01MA06 Norfloxacin(O) 59584 g 0,8 g 0,1536
J01MA12 Levofloxacin(O) 8718,5 g 0,5 g 0,0360
J01MA12 Levofloxacin(P) 475 g 0,5 g 0,0020
J01MA14 Moxifloxacin(O) 9532 g 0,4 g 0,0491
J01MA14 Moxifloxacin(P) 263,6 g 0,4 g 0,0014
J01X OTHER ANTIBACTERIALS 0,7504
J01XA Glycopeptide antibacterials 0,0248
J01XA01 Vancomycin(O) 12 g 2 g <0,0001
J01XA01 Vancomycin(P) 23935 g 2 g 0,0247
J01XA02 Teicoplanin(P) 12 g 0,4 g 0,0001
J01XB Polymyxins 0,0020
J01XB01 Colistin(I, P) 1170000000 U 9000000 U 0,0003
J01XB01 Colistin(P) 7650000000 U 9000000 U 0,0018
J01XD Imidazole derivatives 0,2291
J01XD01 Metronidazole (O) 181715 g 2 g 0,1874
J01XD01 Metronidazole (P) 30350 g 1,5 g 0,0417
20/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J01XE Nitrofuran derivatives 0,4697
J01XE01 Nitrofurantoin(O) 45552,5 g 0,2 g 0,4697
J01XX Other antibacterials 0,0249
J01XX01 Fosfomycin(O) 13338 g 3 g 0,0092
J01XX08 Linezolid(O) 7008 g 1,2 g 0,0120
J01XX08 Linezolid(P) 1404 g 1,2 g 0,0024
J01XX09 Daptomycin(P) 172,4 g 0,28 g 0,0013
J02 ANTIMYCOTICS FOR SYSTEMIC USE 0,3909
J02A ANTIMYCOTICS FOR SYSTEMIC USE 0,3909
J02AA Antibiotics 0,0096
J02AA01 Amphotericin(O) 234 g
J02AA01 Amphotericin(P) 162,75 g 0,035 g 0,0096
J02AC Triazole derivatives 0,3704
J02AC01 Fluconazole(O) 13979,95 g 0,2 g 0,1441
J02AC01 Fluconazole(P) 3298,6 g 0,2 g 0,0340
J02AC02 Itraconazole(O) 15481 g 0,2 g 0,1596
J02AC03 Voriconazole(O) 2014,8 g 0,4 g 0,0104
J02AC03 Voriconazole(P) 129 g 0,4 g 0,0007
J02AC04 Posaconazole(O) 3100,8 g 0,3 g 0,0213
J02AC05 Isavuconazole(O) 26,6 g 0,2 g 0,0003
J02AC05 Isavuconazole(P) 3,2 g 0,2 g <0,0001
J02AX Other antimycotics for systemic use 0,0109
J02AX04 Caspofungin(P) 103,27 g 0,05 g 0,0043
J02AX06 Anidulafungin(P) 322,6 g 0,1 g 0,0067
J04 ANTIMYCOBACTERIALS 0,2924
J04A DRUGS FOR TREATMENT OF TUBERCULOSIS 0,2631
J04AA Aminosalicylic acid and derivatives 0,0005
J04AA01 Paraaminosalicylic acid(O) 3000 g 12 g 0,0005
J04AB Antibiotics 0,0569
J04AB01 Cycloserine(O) 6000 g 0,75 g 0,0165
J04AB02 Rifampicin(O) 11685,6 g 0,6 g 0,0402
J04AB02 Rifampicin(P) 60 g 0,6 g 0,0002
J04AK Other drugs for treatment of tuberculosis 0,1665
J04AK01 Pyrazinamide(O) 30000 g 1,5 g 0,0412
J04AK02 Ethambutol(O) 67400 g 1,2 g 0,1158
J04AK05 Bedaquiline(O) 394,8 g 86 mg 0,0095
J04AM Combinations of drugs for treatment of tuberculosis 0,0392
J04AM02 Rifampicin+Isoniazid(O) 8000 pieces 4 pieces 0,0041
J04AM02 Rifampicin+Isoniazid(O) 34000 pieces 2 pieces 0,0351
J04B DRUGS FOR TREATMENT OF LEPRA 0,0293
J04BA Drugs for treatment of lepra 0,0293
J04BA01 Clofazimine(O) 800 g 0,1 g 0,0165
J04BA02 Dapsone(O) 310 g 0,05 g 0,0128
J05 ANTIVIRALS FOR SYSTEMIC USE 6,3840
J05A DIRECT ACTING ANTIVIRALS 6,3840
J05AB Nucleosides and nucleotides excl. reverse transcriptase
inhibitors 0,4043
J05AB01 Aciclovir(O) 392911,5 g 4 g 0,2026
J05AB01 Aciclovir(P) 3823,75 g 4 g 0,0020
J05AB06 Ganciclovir(P) 375,5 g 0,5 g 0,0015
J05AB09 Famciclovir(O) 168 g 0,75 g 0,0005
J05AB11 Valaciclovir(O) 268834 g 3 g 0,1848
J05AB12 Cidofovir(P) 1,5 g 0,025 g 0,0001
J05AB14 Valganciclovir(O) 5619 g 0,9 g 0,0129
J05AB80 Remdesivir(P) 163,4 g
J05AE Protease inhibitors 0,3255
J05AE03 Ritonavir(O) 21048 g 1,2 g 0,0362
J05AE10 Darunavir(O) 168384 g 1,2 g 0,2893
J05AF Nucleoside and nucleotide reverse transcriptase inhibitors 0,1236
J05AF01 Zidovudine(O) 198 g 0,6 g 0,0007
21/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J05AF01 Zidovudine(P) 39 g 0,6 g 0,0001
J05AF05 Lamivudine(O) 1821 g 0,3 g 0,0125
J05AF06 Abacavir(O) 1755,6 g 0,6 g 0,0060
J05AF07 Tenofovir disoproxil(O) 235,2 g 0,245 g 0,0020
J05AF10 Entecavir(O) 23,805 g 0,5 mg 0,0982
J05AF13 Tenofovir alafenamide(O) 49,5 g 25 mg 0,0041
J05AG Non-nucleoside reverse transcriptase inhibitors 0,8082
J05AG03 Efavirenz(O) 43560 g 0,6 g 0,1497
J05AG05 Rilpivirine(O) 7983,75 g 25 mg 0,6585
J05AH Neuraminidase inhibitors 0,1187
J05AH02 Oseltamivir(O) 8637,75 g 0,15 g 0,1187
J05AJ Integrase inhibitors 0,9169
J05AJ01 Raltegravir(O) 324120 g 0,8 g 0,8354
J05AJ03 Dolutegravir(O) 1974,75 g 50 mg 0,0814
J05AP Antivirals for treatment of HCV infections 0,0955
J05AP01 Ribavirin(O) 392 g 1 g 0,0008
J05AP54 Elbasvir+Grazoprevir(O) 1540 pieces 1 pieces 0,0032
J05AP55 Sofosbuvir+Velpatasvir(O) 5460 pieces 1 pieces 0,0113
J05AP57 Glecaprevir+Pibrentasvir(O) 116760 pieces 3 pieces 0,0803
J05AR Antivirals for treatment of HIV infections, combinations 3,5780
J05AR01 Zidovudine+Lamivudine(O) 40380 pieces 2 pieces 0,0416
J05AR02 Lamivudine+Abacavir(O) 332850 pieces 1 pieces 0,6864
J05AR03 Tenofovir disoproxil+Emtricitabine(O) 841590 pieces 1 pieces 1,7354
J05AR06 Emtricitabine+Tenofovir disoproxil+Efavirenz(O) 33720 pieces 1 pieces 0,0695
J05AR10 Lopinavir+Ritonavir(O) 168 g 0,8 g 0,0004
J05AR13 Lamivudine+Abacavir+Dolutegravir(O) 287040 pieces 1 pieces 0,5919
J05AR14 Darunavir+Cobicistat(O) 219180 pieces 1 pieces 0,4520
J05AR18 Emtricitabine+Tenofovir
alafenamide+Elvitegravir+Cobicistat(O) 360 pieces 1 pieces 0,0007
J05AX Other antivirals 0,0133
J05AX27 Favipiravir(O) 10296 g 1,6 g 0,0133
J06 IMMUNE SERA AND IMMUNOGLOBULINS
J06A IMMUNE SERA
J06AA Immune sera
J06AA01 Diphtheria antitoxin(P) 200000 U
J06AA03 Snake venom antiserum(P) 70 pieces
J06B IMMUNOGLOBULINS
J06BA Immunoglobulins, normal human
J06BA01 Immunoglobulins, normal human, for extravascular a(P) 12919,5 g
J06BA02 Immunoglobulins, normal human, for intravascular a(P) 110590 g
J06BB Specific immunoglobulins
J06BB01 Human Anti-D Immunoglobulin(P) 1947125 U
J06BB02 Tetanus immunoglobulin(P) 12000 U
J06BB03 Varicella zoster immunoglobulin(P) 2500 U
J06BB04 Hepatitis B immunoglobulin(P) 2800 U
J06BB05 Rabies immunoglobulin(P) 3000 U
J06BB16 Palivizumab(P) 44,1 g
J07 VACCINES
J07A BACTERIAL VACCINES
J07AG Hemophilus influenzae B vaccines
J07AG01 Haemophilus influenzae B, purified antigen conjugated(P) 373 doses
J07AH Meningococcal vaccines
J07AH08 Meningococcus, tetravalent purified polysaccharides antigen
conjugated(P) 507 doses
J07AH09 Meningococcus B, multicomponent vaccine(P) 42 doses
J07AL Pneumococcal vaccines
J07AL01 Pneumococcus, purified polysaccharides antigen(P) 1110 doses
J07AL02 Pneumococcus, purified polysaccharides antigen
conjugated(P) 4838 doses
22/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J07AL52 Pneumococcus, purified polysaccharides antigen+Haemophilus
influenzae, conjugated(P) 228 doses
J07AM Tetanus vaccines
J07AM51 Tetanus toxoid+Diphtheria toxoid(P) 23175 doses
J07AN Tuberculosis vaccines
J07AN01 Tuberculosis, live attenuated(P) 23260 doses
J07AP Typhoid vaccines
J07AP03 Typhoid, purified polysaccharide antigen(P) 825 doses
J07AX Other bacterial vaccines
J07AX80 Diphtheria-tetanus-pertussis(P) 17482 doses
J07B VIRAL VACCINES
J07BA Encephalitis vaccines
J07BA01 Encephalitis, tick borne, inactivated, whole virus(P) 88374 doses
J07BB Influenza vaccines
J07BB02 Influenza, inactivated, split virus or surface antigen(P) 153821 doses
J07BC Hepatitis vaccines
J07BC01 Hepatitis B, purified antigen(P) 3303 doses
J07BC02 Hepatitis A, inactivated, whole virus(P) 4308 doses
J07BC80 Hepatitis A, inactivated, whole virus+Hepatitis B, purified
antigen(P) 1625 doses
J07BD Measles vaccines
J07BD52 Measles, live attunated+Rubella, live attenuated+Mumps,
live,attenuated(P) 31091 doses
J07BF Poliomyelitis vaccines
J07BF03 Poliomyelitis, trivalent, inactivated, whole virus(P) 607 doses
J07BG Rabies vaccines
J07BG01 Rabies, inactivated, whole virus(P) 1774 doses
J07BH Rota virus diarrhea vaccines
J07BH02 Rota virus, pentavalent, live, reassorted(O) 64411 doses
J07BK Varicella zoster vaccines
J07BK01 Varicella, live attenuated(P) 2096 doses
J07BK02 Zoster, live attenuated(P) 40 doses
J07BK03 Zoster, purified antigen(P) 5 doses
J07BL Yellow fever vaccines
J07BL01 Yellow fever, live attenuated(P) 773 doses
J07BM Papillomavirus vaccines
J07BM02 Papillomavirus (human types 16, 18)(P) 9 doses
J07BM03 Papillomavirus (human types 6, 11, 16, 18, 31, 33, 45, 52,
58)(P) 12056 doses
J07BX Other viral vaccines
J07BX03 Covid-19 vaccine(P) 6099,6 doses
J07C BACTERIAL AND VIRAL VACCINES, COMBINED
J07CA Bacterial and viral vaccines, combined
J07CA02 Diphtheria toxoid+Pertussis, purified antigen+Tetanus
toxoid+Poliomyelitis, trivalent, inactivated, whole virus(P) 15054 doses
J07CA06
Diphtheria toxoid+Tetanus toxoid+Pertussis, purified
antigen+Poliomyelitis, trivalent, inactivated, whole
virus+Haemophilus influenzae B, purified antigen
conjugated(P)
1049 doses
J07CA09
Diphtheria toxoid+Poliomyelitis, trivalent, inactivated, whole
virus+Pertussis, purified antigen+Haemophilus influenzae B,
purified antigen conjugated+Hepatitis B, purified
antigen+Tetanus toxoid(P)
48420 doses
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS 12,4653
L01 ANTINEOPLASTIC AGENTS
L01A ALKYLATING AGENTS
L01AA Nitrogen mustard analogues
L01AA01 Cyclophosphamide(O) 627,5 g
L01AA01 Cyclophosphamide(P) 3931 g
L01AA02 Chlorambucil(O) 22,9 g
L01AA03 Melphalan(O) 4,7 g
23/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01AA03 Melphalan(P) 26,1 g
L01AA06 Ifosfamide(P) 1640 g
L01AA09 Bendamustine(P) 121 g
L01AB Alkyl sulfonates
L01AB01 Busulfan(O) 7 g
L01AB01 Busulfan(P) 4,32 g
L01AB02 Treosulfan(P) 1375 g
L01AC Ethylene imines
L01AC01 Thiotepa(P) 6,805 g
L01AD Nitrosoureas
L01AD01 Carmustine(P) 13,8 g
L01AD02 Lomustine(O) 16,4 g
L01AX Other alkylating agents
L01AX03 Temozolomide(O) 609,35 g
L01AX04 Dacarbazine(P) 395 g
L01B ANTIMETABOLITES
L01BA Folic acid analogues
L01BA01 Methotrexate(P) 1624,1 g
L01BA04 Pemetrexed(P) 431 g
L01BB Purine analogues
L01BB02 Mercaptopurine(O) 417,5 g
L01BB03 Tioguanine(O) 9 g
L01BB04 Cladribine(P) 0,34 g
L01BB05 Fludarabine(P) 17,85 g
L01BB07 Nelarabine(P) 4,5 g
L01BC Pyrimidine analogues
L01BC01 Cytarabine(P) 2458 g
L01BC02 Fluorouracil(P) 14785 g
L01BC05 Gemcitabine(P) 5450,3596 g
L01BC06 Capecitabine(O) 252768 g
L01BC07 Azacitidine(P) 283,7 g
L01BC83 Trifluridine+Tipiracil(O) 17480 pieces
L01C PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS
L01CA Vinca alkaloids and analogues
L01CA01 Vinblastine(P) 5,52 g
L01CA02 Vincristine(P) 2,221 g
L01CA04 Vinorelbine(O) 2,2 g
L01CA04 Vinorelbine(P) 14,6 g
L01CB Podophyllotoxin derivatives
L01CB01 Etoposide(O) 341 g
L01CB01 Etoposide(P) 502,3 g
L01CD Taxanes
L01CD01 Paclitaxel(P) 777,7 g
L01CD02 Docetaxel(P) 412 g
L01CD04 Cabazitaxel(P) 5,7 g
L01CE Topoisomerase 1 (TOP1) inhibitors
L01CE01 Topotecan(P) 3,521 g
L01CE02 Irinotecan(P) 681 g
L01D CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
L01DA Actinomycines
L01DA01 Dactinomycin(P) 0,015 g
L01DB Anthracyclines and related substances
L01DB01 Doxorubicin(P) 136,39 g
L01DB02 Daunorubicin(P) 11,28 g
L01DB03 Epirubicin(P) 187,5 g
L01DB06 Idarubicin(P) 2,16 g
L01DB07 Mitoxantrone(P) 1,88 g
L01DB11 Pixantrone(P) 1,015 g
L01DC Other cytotoxic antibiotics
24/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01DC01 Bleomycin(P) 9795000 U
L01DC03 Mitomycin(P) 5,76 g
L01E PROTEIN KINASE INHIBITORS
L01EA BCR-ABL tyrosine kinase inhibitors
L01EA01 Imatinib(O) 16512 g
L01EA02 Dasatinib(O) 648 g
L01EA03 Nilotinib(O) 8624 g
L01EA04 Bosutinib(O) 252 g
L01EA05 Ponatinib(O) 8,1 g
L01EB Epidermal growth factor receptor (EGFR) tyrosine kinase
inhibitors
L01EB01 Gefitinib(O) 1005 g
L01EB02 Erlotinib(O) 117 g
L01EB03 Afatinib(O) 129,64 g
L01EB04 Osimertinib(O) 210 g
L01EC B-Raf serine-threonine kinase (BRAF) inhibitors
L01EC02 Dabrafenib(O) 3672 g
L01ED Anaplastic lymphoma kinase (ALK) inhibitors
L01ED01 Crizotinib(O) 345 g
L01ED02 Ceritinib(O) 270 g
L01ED04 Brigatinib(O) 90,72 g
L01EE Mitogen-activated protein kinase (MEK) inhibitors
L01EE01 Trametinib(O) 25,86 g
L01EF Cyclin-dependent kinase (CDK) inhibitors
L01EF01 Palbociclib(O) 1096,2 g
L01EF02 Ribociclib(O) 3376,8 g
L01EG Mammalian target of rapamycin (mTOR) kinase inhibitors
L01EG01 Temsirolimus(P) 0,81 g
L01EG02 Everolimus(O) 43,2 g
L01EH Human epidermal growth factor receptor 2 (HER2) tyrosine
kinase inhibitors
L01EH01 Lapatinib(O) 52,5 g
L01EJ Janus-associated kinase (JAK) inhibitors
L01EJ01 Ruxolitinib(O) 254,8 g
L01EK Vascular endothelial growth factor receptor (VEGFR) tyrosine
kinase inhibitors
L01EK01 Axitinib(O) 28 g
L01EL Bruton's tyrosine kinase (BTK) inhibitors
L01EL01 Ibrutinib(O) 9151,8 g
L01EX Other protein kinase inhibitors
L01EX01 Sunitinib(O) 288,4 g
L01EX02 Sorafenib(O) 4368 g
L01EX03 Pazopanib(O) 13824 g
L01EX05 regorafenib(O) 235,2 g
L01EX07 Cabozantinib(O) 442,96 g
L01EX08 Lenvatinib(O) 1,74 g
L01EX09 Nintedanib(O) 5871 g
L01EX10 Midostaurin(O) 60,2 g
L01X OTHER ANTINEOPLASTIC AGENTS
L01XA Platinum compounds
L01XA01 Cisplatin(P) 189,8 g
L01XA02 Carboplatin(P) 1883,4 g
L01XA03 Oxaliplatin(P) 887,4 g
L01XB Methylhydrazines
L01XB01 Procarbazine(O) 187,5 g
L01XC Monoclonal antibodies
L01XC02 Rituximab(P) 2147,96 g
L01XC03 Trastuzumab(P) 1734,15 g
L01XC06 Cetuximab(P) 109,2 g
L01XC07 Bevacizumab(P) 1178,2 g
25/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01XC08 Panitumumab(P) 108,6 g
L01XC11 Ipilimumab(P) 1,95 g
L01XC12 Brentuximab vedotin(P) 11,5 g
L01XC13 Pertuzumab(P) 308,7 g
L01XC14 Trastuzumab emtansine(P) 76,68 g
L01XC15 Obinutuzumab(P) 135 g
L01XC17 Nivolumab(P) 212,34 g
L01XC18 Pembrolizumab(P) 328,6 g
L01XC19 Blinatumomab(P) 0,0026 g
L01XC21 Ramucirumab(P) 4 g
L01XC24 Daratumumab(P) 467,6 g
L01XC26 Inotuzumab ozogamicin(P) 0,003 g
L01XC28 Durvalumab(P) 364,68 g
L01XC32 Atezolizumab(P) 289,2 g
L01XC80 Dinutuximab beta(P) 0,405 g
L01XD Sensitizers used in photodynamic/radiation therapy
L01XD04 Aminolevulinic acid(O) 7,5 g
L01XF Retinoids for cancer treatment
L01XF01 Tretinoin(O) 42 g
L01XG Proteasome inhibitors
L01XG01 Bortezomib(P) 8,897 g
L01XG02 Carfilzomib(P) 2,64 g
L01XG03 Ixazomib(O) 0,18 g
L01XK Poly (ADP-ribose) polymerase (PARP) inhibitors
L01XK01 Olaparib(O) 9260,8 g
L01XX Other antineoplastic agents
L01XX02 Asparaginase(P) 1100000 U
L01XX05 Hydroxycarbamide(O) 255250 g
L01XX11 Estramustine(O) 123,2 g
L01XX23 Mitotane(O) 950 g
L01XX24 Pegaspargase(P) 390000 U
L01XX27 Arsenic trioxide(P) 3,5 g
L01XX35 Anagrelide(O) 1,15 g
L01XX41 Eribulin(P) 0,095 g
L01XX52 Venetoclax(O) 1367,87 g
L02 ENDOCRINE THERAPY 4,7298
L02A HORMONES AND RELATED AGENTS 0,6680
L02AB Progestogens 0,0085
L02AB02 Medroxyprogesterone(O) 4110 g 1 g 0,0085
L02AE Gonadotropin releasing hormone analogues 0,6595
L02AE03 Goserelin(P) 9,5832 g 0,129 mg 0,1532
L02AE04 Triptorelin(P) 0,2429 g 0,1 mg 0,0050
L02AE04 Triptorelin(P) 32,5762 g 0,134 mg 0,5013
L02B HORMONE ANTAGONISTS AND RELATED AGENTS 4,0619
L02BA Anti-estrogens 0,8118
L02BA01 Tamoxifen(O) 6229,2 g 0,02 g 0,6423
L02BA03 Fulvestrant(P) 682,5 g 8,3 mg 0,1696
L02BB Anti-androgens 1,2948
L02BB03 Bicalutamide(O) 30907,8 g 0,05 g 1,2747
L02BB04 enzalutamide
(O) 1379,84 g 0,16 g 0,0178
L02BB05 Apalutamide(O) 273,6 g 0,24 g 0,0024
L02BG Aromatase inhibitors 1,8432
L02BG03 Anastrozole(O) 334,908 g 1 mg 0,6906
L02BG04 Letrozole(O) 1252,95 g 2,5 mg 1,0335
L02BG06 Exemestane(O) 1443,75 g 0,025 g 0,1191
L02BX Other hormone antagonists and related agents 0,1121
L02BX03 Abiraterone(O) 54360 g 1 g 0,1121
L03 IMMUNOSTIMULANTS 0,6028
L03A IMMUNOSTIMULANTS 0,6028
L03AA Colony stimulating factors 0,0904
26/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L03AA02 Filgrastim(P) 9,5856 g 0,35 mg 0,0565
L03AA13 Pegfilgrastim(P) 4,932 g 0,3 mg 0,0339
L03AB Interferons 0,3958
L03AB04 Interferon alfa-2a(P) 19131000000 U 2000000 U 0,0197
L03AB07 Interferon beta-1a(P) 0,5849 g 0,0043 mg 0,2805
L03AB08 Interferon beta-1b(P) 99720000000 U 4000000 U 0,0514
L03AB11 Peginterferon alfa-2a(P) 0,0111 g 0,026 mg 0,0009
L03AB13 Peginterferon beta-1a(P) 0,1868 g 8,9 mcg 0,0433
L03AX Other immunostimulants 0,1166
L03AX03 BCG bacteria(P) 2,8375 g 1,8 mg 0,0033
L03AX13 Glatiramer acetate(P) 1099,12 g 0,02 g 0,1133
L03AX16 Plerixafor(P) 0,528 g 16,8 mg 0,0001
L03AX80 Methyluracil(R) 240 g
L04 IMMUNOSUPPRESSANTS 7,1326
L04A IMMUNOSUPPRESSANTS 7,1326
L04AA Selective immunosuppressants 1,1772
L04AA03 Antilymphocyte immunoglobulin (horse)(P) 35 g
L04AA04 Rabbit anti-T-lymphocyte immunoglobulin(P) 19,525 g 0,1 g 0,0004
L04AA06 Mycophenolic acid(O) 309567,4 g 2 g 0,3192
L04AA06 Mycophenolic acid(P) 324 g 2 g 0,0003
L04AA10 Sirolimus(O) 22,56 g 0,003 g 0,0155
L04AA13 Leflunomide(O) 5352,9 g 0,02 g 0,5519
L04AA18 Everolimus(O) 0,36 g 1,5 mg 0,0005
L04AA23 Natalizumab(P) 47,4 g 0,01 g 0,0098
L04AA24 Abatacept(P) 174 g 0,027 g 0,0133
L04AA25 Eculizumab(P) 84,3 g 0,064 g 0,0027
L04AA26 Belimumab(P) 9,2 g 25 mg 0,0008
L04AA27 Fingolimod(O) 5,11 g 0,5 mg 0,0211
L04AA29 Tofacitinib
(O) 98 g 10 mg 0,0202
L04AA31 Teriflunomide(O) 685,608 g 14 mg 0,1010
L04AA32 Apremilast(O) 4,05 g 60 mg 0,0001
L04AA33 Vedolizumab(P) 103,5 g 5,4 mg 0,0395
L04AA34 Alemtuzumab(P) 0,252 g 0,13 mg 0,0040
L04AA36 Ocrelizumab(P) 104,1 g 3,29 mg 0,0652
L04AA40 Cladribine(O) 1,92 g 0,34 mg 0,0116
L04AA42 Siponimod(O) 0,56 g
L04AA44 Upadacitinib(O) 63,84 g
L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors 1,3593
L04AB01 Etanercept(P) 896,88 g 0,007 g 0,2642
L04AB02 Infliximab(P) 984 g 3,75 mg 0,5411
L04AB04 Adalimumab(P) 642,8 g 2,9 mg 0,4571
L04AB05 Certolizumab pegol(P) 28,8 g 14 mg 0,0042
L04AB06 Golimumab(P) 74,6 g 1,66 mg 0,0927
L04AC Interleukin inhibitors 0,4357
L04AC02 Basiliximab(P) 1,42 g 0,04 g 0,0001
L04AC03 Anakinra(P) 176,5785 g 0,1 g 0,0036
L04AC05 Ustekinumab(P) 54,515 g 0,54 mg 0,2082
L04AC07 Tocilizumab(P) 927,776 g 0,02 g 0,0957
L04AC10 Secukinumab(P) 439,2 g 10 mg 0,0906
L04AC13 Ixekizumab(P) 17,52 g 2,9 mg 0,0125
L04AC14 Sarilumab(P) 103,4 g 14,3 mg 0,0149
L04AC16 Guselkumab(P) 4,2 g 1,79 mg 0,0048
L04AC18 Risankizumab(P) 4,35 g 1,67 mg 0,0054
L04AD Calcineurin inhibitors 0,5308
L04AD01 Ciclosporin(O) 26086,25 g 0,25 g 0,2152
L04AD01 Ciclosporin(P) 85 g 0,25 g 0,0007
L04AD02 Tacrolimus(O) 763,5125 g 5 mg 0,3149
L04AD02 Tacrolimus(P) 0,2 g 5 mg 0,0001
L04AX Other immunosuppressants 3,6297
L04AX01 Azathioprine(O) 29045 g 0,15 g 0,3993
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Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L04AX02 Thalidomide(O) 434 g 0,1 g 0,0089
L04AX03 Methotrexate(O) 3437,5 g 2,5 mg 2,8353
L04AX03 Methotrexate(P) 129,835 g 2,5 mg 0,1071
L04AX04 Lenalidomide(O) 380,205 g 0,01 g 0,0784
L04AX05 Pirfenidone(O) 25837,056 g 2,4 g 0,0222
L04AX06 Pomalidomide
(O) 17,556 g 3 mg 0,0121
L04AX07 Dimethyl fumarate(O) 38718,96 g 0,48 g 0,1663
M MUSCULO-SKELETAL SYSTEM 84,4914
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS 69,3257
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS,
NON-STEROIDS 69,3145
M01AB Acetic acid derivatives and related substances 8,9249
M01AB01 Indometacin(O) 3565,5 g 0,1 g 0,0735
M01AB05 Diclofenac(O) 326928,5 g 0,1 g 6,7415
M01AB05 Diclofenac(P) 8213,625 g 0,1 g 0,1694
M01AB05 Diclofenac(R) 13236,875 g 0,1 g 0,2730
M01AB16 Aceclofenac(O) 41698 g 0,2 g 0,4299
M01AB82 Diclofenac+Omeprazole(O) 60018,75 g 0,1 g 1,2376
M01AC Oxicams 3,7597
M01AC01 Piroxicam(O) 1258,4 g 0,02 g 0,1297
M01AC05 Lornoxicam(O) 1246,24 g 0,012 g 0,2142
M01AC05 Lornoxicam(P) 4,08 g 0,012 g 0,0007
M01AC06 Meloxicam(O) 24630,525 g 0,015 g 3,3860
M01AC06 Meloxicam(P) 211,825 g 0,015 g 0,0291
M01AE Propionic acid derivatives 39,5921
M01AE01 Ibuprofen(O) 14565502 g 1,2 g 25,0292
M01AE01 Ibuprofen(P) 6586 g 1,2 g 0,0113
M01AE02 Naproxen(O) 738728,65 g 0,5 g 3,0466
M01AE03 Ketoprofen(O) 123315,625 g 0,15 g 1,6952
M01AE03 Ketoprofen(P) 13023 g 0,15 g 0,1790
M01AE03 Ketoprofen(R) 1,2 g 0,15 g <0,0001
M01AE17 Dexketoprofen(O) 75805,25 g 0,075 g 2,0842
M01AE17 Dexketoprofen(P) 3606,5 g 0,075 g 0,0992
M01AE52 Naproxen+Esomeprazole(O) 1803045 g 0,5 g 7,4360
M01AE82 Ibuprofen+Phenylephrine(O) 6561,6 g 1,2 g 0,0113
M01AG Fenamates 0,0044
M01AG02 Tolfenamic acid(O) 636 g 0,3 g 0,0044
M01AH Coxibs 9,2549
M01AH01 Celecoxib(O) 80092 g 0,2 g 0,8258
M01AH05 Etoricoxib(O) 245263,41 g 60 mg 8,4292
M01AX Other antiinflammatory and antirheumatic agents, non-steroids 7,7785
M01AX01 Nabumetone(O) 146460 g 1 g 0,3020
M01AX05 Glucosamine(O) 5438609,76 g 1,5 g 7,4765
M01C SPECIFIC ANTIRHEUMATIC AGENTS 0,0112
M01CC Penicillamine and similar agents 0,0112
M01CC01 Penicillamine(O) 2712,5 g 0,5 g 0,0112
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA10 Ketoprofen(C) 1158850 g
M02AA12 Naproxen(C) 994675 g
M02AA13 Ibuprofen(C) 13002 pieces
M02AA13 Ibuprofen(C) 902450 g
M02AA15 Diclofenac(C) 450690 pieces
M02AA15 Diclofenac(C) 32066799,7 g
M02AA81 Ibuprofen+Levomenthol(C) 1700900 g
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Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
M02AC Preparations with salicylic acid derivatives
M02AC80 Methyl salicylate+Levomenthol+Eucalyptus oil+Turpentine
oil(C) 93867 g
M02AX Other topical products for joint and muscular pain
M02AX80 Nicoboxil+Nonivamide(C) 186240 g
M02AX90 Camphor+Salicylic acid+Turpentine oil+Venenum Viperae
berus(C) 747000 g
M02AX92 Benzyl nicotinate+Nonivamide+Camphor+Turpentine
oil+Dimethyl sulfoxide(C) 747800 g
M03 MUSCLE RELAXANTS 0,9980
M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
M03AB Choline derivatives
M03AB01 Suxamethonium chloride(P) 3593 g
M03AC Other quaternary ammonium compounds
M03AC04 Atracurium besilate(P) 1583,75 g
M03AC06 Pipecuronium bromide(P) 35 g
M03AC09 Rocuronium bromide(P) 1090,25 g
M03AX Other muscle relaxants, peripherally acting agents
M03AX01 Botulinum toxin(P) 1477150 U
M03B MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS 0,9980
M03BX Other centrally acting agents 0,9980
M03BX01 Baclofen(O) 4939,25 g 0,05 g 0,2037
M03BX01 Baclofen(P) 2,6215 g 0,55 mg 0,0098
M03BX02 Tizanidine(O) 4565,04 g 0,012 g 0,7845
M04 ANTIGOUT PREPARATIONS 9,5556
M04A ANTIGOUT PREPARATIONS 9,5556
M04AA Preparations inhibiting uric acid production 9,5445
M04AA01 Allopurinol(O) 1269495,8 g 0,4 g 6,5445
M04AA03 Febuxostat(O) 116389,28 g 0,08 g 3,0000
M04AB Preparations increasing uric acid excretion 0,0032
M04AB01 Probenecid(O) 50 g 1 g 0,0001
M04AB03 Benzbromarone(O) 149 g 0,1 g 0,0031
M04AC Preparations with no effect on uric acid metabolism 0,0079
M04AC01 Colchicine(O) 3,835 g 1 mg 0,0079
M05 DRUGS FOR TREATMENT OF BONE DISEASES 4,6122
M05B DRUGS AFFECTING BONE STRUCTURE AND
MINERALIZATION 4,6122
M05BA Bisphosphonates 0,7983
M05BA03 Pamidronic acid(P) 13,89 g 0,06 g 0,0005
M05BA04 Alendronic acid(O) 223,72 g 0,01 g 0,0461
M05BA06 Ibandronic acid(O) 1364,7 g 0,005 g 0,5628
M05BA06 Ibandronic acid(P) 0,12 g 0,006 g <0,0001
M05BA07 Risedronic acid(O) 437,36 g 0,005 g 0,1804
M05BA08 Zoledronic acid(P) 16,365 g 0,004 g 0,0084
M05BB Bisphosphonates, combinations 2,6506
M05BB03 Alendronic acid+Colecalciferol(O) 12854,24 g 10 mg 2,6506
M05BX Other drugs affecting bone structure and mineralization 1,1633
M05BX04 Denosumab(P) 186,16 g 0,33 mg 1,1633
M05BX05 Burosumab(P) 1,35 g
N NERVOUS SYSTEM 142,3143
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AB Halogenated hydrocarbons
N01AB06 Isoflurane(I) 15000 ml
N01AB07 Desflurane(I) 72960 ml
N01AB08 Sevoflurane(I) 821750 ml
N01AF Barbiturates, plain
N01AF03 Thiopental(P) 1790 g
N01AH Opioid anesthetics
N01AH01 Fentanyl(I) 30,7205 g
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Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N01AH06 Remifentanil(P) 18,37 g
N01AX Other general anesthetics
N01AX03 Ketamine(P) 551 g
N01AX07 Etomidate(P) 57,2 g
N01AX10 Propofol(P) 70630 g
N01AX11 Sodium oxybate(P) 120 g
N01AX13 Nitrous oxide(I) 10162000 ml
N01AX14 Esketamine(P) 226,5 g
N01B ANESTHETICS, LOCAL
N01BA Esters of aminobenzoic acid
N01BA02 Procaine(P) 40 g
N01BB Amides
N01BB01 Bupivacaine(Infilt, P) 2841 g
N01BB01 Bupivacaine(P) 238,25 g
N01BB02 Lidocaine(C) 2050 ml
N01BB02 Lidocaine(C) 2357,5 g
N01BB02 Lidocaine(NA) 2400 ml
N01BB02 Lidocaine(NA) 5719 g
N01BB02 Lidocaine(O) 72240 g
N01BB02 Lidocaine(P) 27198,6 g
N01BB03 Mepivacaine(dental) 1443,3 g
N01BB08 Articaine(P) 0,8 g
N01BB09 Ropivacaine(P) 745,9 g
N01BB80 Articaine+Epinephrine(dental) 841840 ml
N01BB80 Articaine+Epinephrine(O) 438660 ml
N01BB81 Bupivacaine+Epinephrine(P) 250000 ml
N01BB82 Lidocaine+Epinephrine(dental) 67900 ml
N01BB83 Lidocaine+Prilocaine(C) 53945,25 g
N01BB86 Lidocaine+Chlorhexidine(urethral) 930312,5 g
N01BC Esters of benzoic acid
N01BC01 Cocaine(NA) 310 g
N01BX Other local anesthetics
N01BX04 Capsaicin(C) 75,0904 g
N02 ANALGESICS 26,7993
N02A OPIOIDS 8,8276
N02AA Natural opium alkaloids 0,8756
N02AA01 Morphine(O) 5806,8 g 0,1 g 0,1197
N02AA01 Morphine(P) 809,8 g 0,03 g 0,0557
N02AA05 Oxycodone(O) 20429,1 g 0,075 g 0,5617
N02AA05 Oxycodone(P) 228,6 g 0,03 g 0,0157
N02AA08 Dihydrocodeine(O) 8413,2 g 0,15 g 0,1157
N02AA55 Oxycodone+Naloxone(O) 260,55 g 75 mg 0,0072
N02AB Phenylpiperidine derivatives 0,1430
N02AB02 Pethidine(P) 33 g 0,4 g 0,0002
N02AB02 Pethidine(P, V) 1922,5 g 0,4 g 0,0099
N02AB03 Fentanyl(O) 3,4736 g
N02AB03 Fentanyl(SL) 3,243 g 0,6 mg 0,0111
N02AB03 Fentanyl(TD) 70,8412 g 1,2 mg 0,1217
N02AE Oripavine derivatives 0,0163
N02AE01 Buprenorphine(TD) 9,5088 g 1,2 mg 0,0163
N02AJ Opioids in combination with non-opioid analgesics 5,8990
N02AJ06 Codeine+Paracetamol(O) 6878930 pieces 3 pieces 4,7283
N02AJ13 Tramadol+Paracetamol(O) 1992 g 150 mg 0,0274
N02AJ14 Tramadol+Dexketoprofen(O) 83172,375 g 150 mg 1,1434
N02AX Other opioids 1,8936
N02AX02 Tramadol(O) 271498 g 0,3 g 1,8662
N02AX02 Tramadol(P) 3992 g 0,3 g 0,0274
N02B OTHER ANALGESICS AND ANTIPYRETICS 16,8943
N02BA Salicylic acid and derivatives 0,9381
N02BA01 Acetylsalicylic acid (O) 1178865,56 g 3 g 0,8103
N02BA01 Acetylsalicylic acid (P) 31 g
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Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N02BA80 Acetylsalicylic acid +Ascorbic acid(O) 185862,4 g 3 g 0,1278
N02BB Pyrazolones 0,0015
N02BB02 Metamizole sodium(O) 240 g 3 g 0,0002
N02BB02 Metamizole sodium(P) 1970 g 3 g 0,0014
N02BB02 Metamizole sodium(P, V) 30 g 3 g <0,0001
N02BE Anilides 15,9547
N02BE01 Paracetamol(O) 17012588,8 g 3 g 11,6937
N02BE01 Paracetamol(P) 324282 g 3 g 0,2229
N02BE01 Paracetamol(R) 58933,7 g 3 g 0,0405
N02BE52 Paracetamol+Pseudoephedrine+Diphenhydramine(O) 73336 g 3 g 0,0504
N02BE75 Paracetamol+Guaifenesin+Phenylephrine(O) 199881,5 g 3 g 0,1374
N02BE81 Paracetamol+Chlorphenamine+Pseudoephedrine+Dextrometh
orphan(O) 412106 g 3 g 0,2833
N02BE83 Paracetamol+Caffeine(O) 245446 g 3 g 0,1687
N02BE84 Paracetamol+Phenylephrine+Ascorbic acid(O) 934201,25 g 3 g 0,6421
N02BE85 Paracetamol+Pheniramine+Ascorbic acid(O) 86508,32 g 3 g 0,0595
N02BE86 Paracetamol+Phenylephrine+Terpin hydrate+Ascorbic
acid+Caffeine(O) 327030 g 3 g 0,2248
N02BE87 Paracetamol+Pseudoephedrine(O) 62200 g 3 g 0,0428
N02BE91 Paracetamol+Ascorbic acid(O) 9510,6 g 3 g 0,0065
N02BE92 Paracetamol+Codeine(O) 1050760 g 3 g 0,7222
N02BE94 Paracetamol+Codeine+Caffeine(O) 1879902 g 3 g 1,2922
N02BE95 Paracetamol+Phenylephrine(O) 69645 g 3 g 0,0479
N02BE97 Paracetamol+Pseudoephedrine+Dextromethorphan(O) 465414 g 3 g 0,3199
N02C ANTIMIGRAINE PREPARATIONS 1,0774
N02CC Selective serotonin (5HT1) agonists 1,0565
N02CC01 Sumatriptan(N) 1,2 g 0,02 g 0,0001
N02CC01 Sumatriptan(O) 21927,6 g 0,05 g 0,9043
N02CC03 Zolmitriptan(O) 66,59 g 2,5 mg 0,0549
N02CC04 Rizatriptan(O) 61,89 g 0,01 g 0,0128
N02CC07 Frovatriptan(O) 102,26 g 2,5 mg 0,0843
N02CD Calcitonin gene-related peptide (CGRP) antagonists 0,0210
N02CD01 Erenumab(P) 22,4 g 2,5 mg 0,0185
N02CD03 fremanezumab(P) 9 g 7,5 mg 0,0025
N03 ANTIEPILEPTICS 11,9146
N03A ANTIEPILEPTICS 11,9146
N03AA Barbiturates and derivatives 0,4563
N03AA02 Phenobarbital(O) 19800 g 0,1 g 0,4083
N03AA02 Phenobarbital(P) 140 g 0,1 g 0,0029
N03AA03 Primidone(O) 27350 g 1,25 g 0,0451
N03AA80 Benzobarbital(O) 150 g
N03AB Hydantoin derivatives 0,0419
N03AB02 Phenytoin(O) 5890 g 0,3 g 0,0405
N03AB02 Phenytoin(P) 200 g 0,3 g 0,0014
N03AD Succinimide derivatives 0,0134
N03AD01 Ethosuximide(O) 8150 g 1,25 g 0,0134
N03AE Benzodiazepine derivatives 0,5825
N03AE01 Clonazepam(O) 2260,02 g 0,008 g 0,5825
N03AF Carboxamide derivatives 2,7683
N03AF01 Carbamazepine(O) 944646 g 1 g 1,9479
N03AF02 Oxcarbazepine(O) 397845 g 1 g 0,8204
N03AG Fatty acid derivatives 1,7071
N03AG01 Valproic acid(O) 1227965 g 1,5 g 1,6881
N03AG01 Valproic acid(P) 1671,3 g 1,5 g 0,0023
N03AG04 Vigabatrin(O) 16200 g 2 g 0,0167
N03AX Other antiepileptics 6,3451
N03AX03 Sultiame(O) 5300 g 0,4 g 0,0273
N03AX09 Lamotrigine(O) 108935,26 g 0,3 g 0,7488
N03AX11 Topiramate(O) 39232,5 g 0,3 g 0,2697
N03AX12 Gabapentin(O) 1639378 g 1,8 g 1,8781
N03AX14 Levetiracetam(O) 582090 g 1,5 g 0,8002
31/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N03AX14 Levetiracetam(P) 690 g 1,5 g 0,0009
N03AX15 Zonisamide(O) 14 g 0,2 g 0,0001
N03AX16 Pregabalin(O) 380276,4 g 0,3 g 2,6139
N03AX17 Stiripentol(O) 1320 g 1 g 0,0027
N03AX18 Lacosamide(O) 39,9 g 0,3 g 0,0003
N03AX22 perampanel(O) 2,016 g 8 mg 0,0005
N03AX23 Brivaracetam(O) 124,6 g 0,1 g 0,0026
N03AX24 Cannabidiol(O) 120 g
N04 ANTI-PARKINSON DRUGS 3,7745
N04A ANTICHOLINERGIC AGENTS 0,5833
N04AA Tertiary amines 0,5833
N04AA01 Trihexyphenidyl(O) 2828,8 g 0,01 g 0,5833
N04B DOPAMINERGIC AGENTS 3,1911
N04BA Dopa and dopa derivatives 1,4809
N04BA03 Levodopa +Carbidopa+Entacapone(O) 72982,5 g 0,45 g 0,3344
N04BA80 Levodopa +Benserazide(O) 324140 g 0,6 g 1,1140
N04BA81 Levodopa +Carbidopa(intestin) 20132 g
N04BA81 Levodopa +Carbidopa(O) 9446 g 0,6 g 0,0325
N04BB Adamantane derivatives 0,3144
N04BB01 Amantadine(O) 30490 g 0,2 g 0,3144
N04BB01 Amantadine(P) 26 g
N04BC Dopamine agonists 0,7696
N04BC04 Ropinirole(O) 1080,996 g 0,006 g 0,3715
N04BC05 Pramipexole(O) 445,4819 g 2,5 mg 0,3674
N04BC07 Apomorphine(P) 297,05 g 20 mg 0,0306
N04BD Monoamine oxidase type B inhibitors 0,6263
N04BD02 Rasagiline(O) 303,726 g 0,001 g 0,6263
N05 PSYCHOLEPTICS 45,4010
N05A ANTIPSYCHOTICS 10,0797
N05AA Phenothiazines with aliphatic side-chain 0,1472
N05AA01 Chlorpromazine(O) 10418,5 g 0,3 g 0,0716
N05AA01 Chlorpromazine(P) 37,5 g 0,1 g 0,0008
N05AA02 Levomepromazine(O) 10852,5 g 0,3 g 0,0746
N05AA02 Levomepromazine(P, V) 12,5 g 0,1 g 0,0003
N05AB Phenothiazines with piperazine structure 0,0866
N05AB02 Fluphenazine(P) 8,625 g 0,001 g 0,0178
N05AB03 Perphenazine(O) 436,4 g 0,03 g 0,0300
N05AB03 Perphenazine(P) 188,268 g 0,01 g 0,0388
N05AB04 Prochlorperazine(O) 0,82 g 0,1 g <0,0001
N05AC Phenothiazines with piperidine structure 0,0009
N05AC01 Periciazine(O) 21,6 g 0,05 g 0,0009
N05AD Butyrophenone derivatives 1,0486
N05AD01 Haloperidol(O) 1988,735 g 0,008 g 0,5126
N05AD01 Haloperidol(P) 1014,575 g 0,008 g 0,2615
N05AD03 Melperone(O) 37695 g 0,3 g 0,2591
N05AD08 Droperidol(P) 18,675 g 2,5 mg 0,0154
N05AE Indole derivatives 0,0824
N05AE03 Sertindole(O) 621,664 g 0,016 g 0,0801
N05AE04 Ziprasidone(O) 89,36 g 0,08 g 0,0023
N05AF Thioxanthene derivatives 0,8488
N05AF01 Flupentixol(O) 363,75 g 0,006 g 0,1250
N05AF01 Flupentixol(P) 124 g 0,004 g 0,0639
N05AF03 Chlorprothixene(O) 29357,5 g 0,3 g 0,2018
N05AF05 Zuclopenthixol(O) 1340,5 g 0,03 g 0,0921
N05AF05 Zuclopenthixol(P) 49,5 g 0,03 g 0,0034
N05AF05 Zuclopenthixol(P) 2637,2 g 0,015 g 0,3625
N05AH Diazepines, oxazepines and thiazepines 5,7949
N05AH02 Clozapine(O) 99170,5 g 0,3 g 0,6817
N05AH03 Olanzapine(O) 11305,56 g 0,01 g 2,3313
N05AH03 Olanzapine(P) 195,16 g 0,01 g 0,0402
N05AH04 Quetiapine(O) 531841 g 0,4 g 2,7417
32/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N05AL Benzamides 0,1349
N05AL01 Sulpiride(O) 20110,5 g 0,8 g 0,0518
N05AL05 Amisulpride(O) 16122 g 0,4 g 0,0831
N05AN Lithium 0,2947
N05AN01 Lithium(O) 128610 g 0,9 g 0,2947
N05AX Other antipsychotics 1,6406
N05AX08 Risperidone(O) 1662,3 g 0,005 g 0,6856
N05AX08 Risperidone(P) 21,7625 g 2,7 mg 0,0166
N05AX12 Aripiprazole(O) 5597,22 g 0,015 g 0,7695
N05AX12 Aripiprazole(P) 9,5842 g 0,015 g 0,0013
N05AX12 Aripiprazole(P) 542,8 g 0,0133 g 0,0842
N05AX13 Paliperidone(P) 98,05 g 2,5 mg 0,0809
N05AX15 Cariprazine(O) 3,738 g 3 mg 0,0026
N05B ANXIOLYTICS 13,1656
N05BA Benzodiazepine derivatives 13,1650
N05BA01 Diazepam(O) 27486,95 g 0,01 g 5,6680
N05BA01 Diazepam(P) 467,3 g 0,01 g 0,0964
N05BA01 Diazepam(R) 63,075 g 0,01 g 0,0130
N05BA04 Oxazepam(O) 1 g 0,05 g <0,0001
N05BA06 Lorazepam(O) 871,71 g 2,5 mg 0,7190
N05BA06 Lorazepam(P) 10,22 g 2,5 mg 0,0084
N05BA08 Bromazepam(O) 5899,53 g 0,01 g 1,2165
N05BA09 Clobazam(O) 326 g 0,02 g 0,0336
N05BA12 Alprazolam(O) 2615,3425 g 0,001 g 5,3930
N05BA80 Phenazepam(O) 8,25 g 0,001 g 0,0170
N05BB Diphenylmethane derivatives 0,0001
N05BB01 Hydroxyzine(O) 3,6 g 0,075 g 0,0001
N05BE Azaspirodecanedione derivatives 0,0005
N05BE01 Buspirone(O) 7,2 g 0,03 g 0,0005
N05C HYPNOTICS AND SEDATIVES 22,1557
N05CD Benzodiazepine derivatives 0,1658
N05CD02 Nitrazepam(O) 209,35 g 0,005 g 0,0863
N05CD05 Triazolam(O) 0,0075 g 0,25 mg 0,0001
N05CD08 Midazolam(O) 0,04 g 0,01 g <0,0001
N05CD08 Midazolam(O) 80,9507 g 0,015 g 0,0111
N05CD08 Midazolam(P) 491,0807 g 0,015 g 0,0675
N05CD08 Midazolam(P, R) 5,25 g 0,015 g 0,0007
N05CF Benzodiazepine related drugs 21,3986
N05CF01 Zopiclone(O) 61256,925 g 7,5 mg 16,8421
N05CF02 Zolpidem(O) 22096,6 g 0,01 g 4,5565
N05CH Melatonin receptor agonists 0,2853
N05CH01 Melatonin(O) 276,71 g 2 mg 0,2853
N05CM Other hypnotics and sedatives 0,3061
N05CM09 Valerianae radix(O) 421890 pieces 3 pieces 0,2900
N05CM18 Dexmedetomidine(P) 7,8008 g 1 mg 0,0161
N06 PSYCHOANALEPTICS 42,2154
N06A ANTIDEPRESSANTS 37,1049
N06AA Non-selective monoamine reuptake inhibitors 1,9309
N06AA02 Imipramine(O) 6,25 g 0,1 g 0,0001
N06AA04 Clomipramine(O) 4758,45 g 0,1 g 0,0981
N06AA04 Clomipramine(P) 2,5 g 0,1 g 0,0001
N06AA09 Amitriptyline(O) 54730,5 g 0,075 g 1,5048
N06AA10 Nortriptyline(O) 11922,5 g 0,075 g 0,3278
N06AB Selective serotonin reuptake inhibitors 21,7827
N06AB03 Fluoxetine(O) 31871,4 g 0,02 g 3,2861
N06AB04 Citalopram(O) 13786,54 g 0,02 g 1,4214
N06AB05 Paroxetine(O) 22537,8 g 0,02 g 2,3237
N06AB06 Sertraline(O) 146511,2 g 0,05 g 6,0423
N06AB08 Fluvoxamine(O) 432 g 0,1 g 0,0089
N06AB10 Escitalopram(O) 42191,8 g 0,01 g 8,7002
N06AF Monoamine oxidase inhibitors, non-selective 0,0091
33/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N06AF04 Tranylcypromine(O) 44 g 0,01 g 0,0091
N06AG Monoamine oxidase type A inhibitors 0,0001
N06AG02 Moclobemide(O) 18 g 0,3 g 0,0001
N06AX Other antidepressants 13,3822
N06AX03 Mianserin(O) 31,8 g 0,06 g 0,0011
N06AX05 Trazodone(O) 15279 g 0,3 g 0,1050
N06AX11 Mirtazapine(O) 38672,46 g 0,03 g 2,6582
N06AX12 Bupropione(O) 128682 g 0,3 g 0,8845
N06AX14 Tianeptine(O) 22753,5 g 0,0375 g 1,2512
N06AX16 Venlafaxine(O) 190464,75 g 0,1 g 3,9275
N06AX18 Reboxetine(O) 0,72 g 0,008 g 0,0002
N06AX21 Duloxetine(O) 74708,04 g 0,06 g 2,5676
N06AX22 Agomelatine(O) 15207,5 g 0,025 g 1,2544
N06AX26 Vortioxetine(O) 3552,64 g 10 mg 0,7326
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND
NOOTROPICS 1,5304
N06BA Centrally acting sympathomimetics 1,2658
N06BA04 Methylphenidate(O) 17228,1 g 0,03 g 1,1842
N06BA07 Modafinil(O) 1179 g 0,3 g 0,0081
N06BA09 Atomoxetine(O) 2853,62 g 0,08 g 0,0736
N06BA12 Lisdexamfetamine dimesylate(O) 7,2 g
N06BC Xanthine derivatives
N06BC81 Caffeine citrate(O, P) 63,6 g
N06BX Other psychostimulants and nootropics 0,2646
N06BX03 Piracetam (O) 295680 g 2,4 g 0,2540
N06BX13 Idebenone(O) 243 g 0,9 g 0,0006
N06BX18 Vinpocetine(O) 72,75 g 15 mg 0,0100
N06BX83 Aminobutyric acid(O) 33115 g
N06D ANTI-DEMENTIA DRUGS 3,5801
N06DA Anticholinesterases 1,1041
N06DA02 Donepezil(O) 4015,76 g 7,5 mg 1,1041
N06DX Other anti-dementia drugs 2,4760
N06DX01 Memantine(O) 4535,52 g 0,02 g 0,4676
N06DX02 Ginkgo folium(O) 116874 g 0,12 g 2,0084
N06DX80 cerebrolysine(P) 4,304 g
N07 OTHER NERVOUS SYSTEM DRUGS 12,2094
N07A PARASYMPATHOMIMETICS 0,3739
N07AA Anticholinesterases 0,3739
N07AA01 neostigmine(O) 1,8 g 0,06 g 0,0001
N07AA01 neostigmine(P) 33,545 g 0,002 g 0,0346
N07AA02 Pyridostigmine bromide(O) 27189 g 0,18 g 0,3115
N07AA03 Distigmine bromide(O) 3,1 g 0,005 g 0,0013
N07AA80 Neostigmine+Glycopyrronium(P) 12850 ml 1 ml 0,0265
N07AX Other parasympathomimetics
N07AX01 Pilocarpine(O) 1,68 g
N07B DRUGS USED IN ADDICTIVE DISORDERS 3,3984
N07BA Drugs used in nicotine dependence 1,8655
N07BA01 Nicotine(O) 17003,7 g 0,03 g 1,1688
N07BA01 Nicotine(TD) 4441,738 g 0,014 g 0,6542
N07BA03 Varenicline(O) 41,222 g 2 mg 0,0425
N07BB Drugs used in alcohol dependence 0,3664
N07BB01 Disulfiram(O) 28410 g 0,2 g 0,2929
N07BB01 Disulfiram(P) 106 g
N07BB03 Acamprosate(O) 447,552 g 2 g 0,0005
N07BB04 Naltrexone(O) 1549,8 g 50 mg 0,0639
N07BB05 nalmefene(O) 79,632 g 18 mg 0,0091
N07BC Drugs used in opioid dependence 1,1665
N07BC02 Methadone(O) 13520 g 0,025 g 1,1152
N07BC51 Buprenorphine+Naloxone(SL) 199,234 g 8 mg 0,0514
N07C ANTIVERTIGO PREPARATIONS 8,4046
N07CA Antivertigo preparations 8,4046
34/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N07CA01 Betahistine(O) 83376,48 g 0,024 g 7,1637
N07CA02 Cinnarizine(O) 51360 g 0,09 g 1,1768
N07CA03 Flunarizine(O) 4,5 g 0,01 g 0,0009
N07CA80 Cinnarizine+Dimenhydrinate(O) 2762 g 90 mg 0,0633
N07X OTHER NERVOUS SYSTEM DRUGS 0,0324
N07XX Other nervous system drugs 0,0324
N07XX02 Riluzole(O) 1352,4 g 0,1 g 0,0279
N07XX06 Tetrabenazine(O) 168 g 0,1 g 0,0035
N07XX07 Fampridine(O) 10,64 g 20 mg 0,0011
N07XX14 Edaravone(P) 8,1 g
P ANTIPARASITIC PRODUCTS, INSECTICIDES AND
REPELLENTS 1,0260
P01 ANTIPROTOZOALS 0,8172
P01A AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL
DISEASES
P01AB Nitroimidazole derivatives
P01AB01 Metronidazole (O, V) 1062 g
P01B ANTIMALARIALS 0,8172
P01BA Aminoquinolines 0,7762
P01BA02 Hydroxychloroquine(O) 194124 g 0,516 g 0,7758
P01BA03 Primaquine(O) 3 g 0,015 g 0,0004
P01BB Biguanides 0,0407
P01BB51 Proguanil+Atovaquone(O) 648 pieces 16 pieces 0,0001
P01BB51 Proguanil+Atovaquone(O) 78852 pieces 4 pieces 0,0406
P01BD Diaminopyrimidines 0,0003
P01BD01 Pyrimethamine(O) 10,5 g 0,075 g 0,0003
P01BE Artemisinin and derivatives, plain <0,0001
P01BE03 Artesunate(P) 0,6 g 0,28 g <0,0001
P02 ANTHELMINTICS 0,2088
P02B ANTITREMATODALS 0,0002
P02BA Quinoline derivatives and related substances 0,0002
P02BA01 Praziquantel(O) 313,2 g 3 g 0,0002
P02C ANTINEMATODAL AGENTS 0,2086
P02CA Benzimidazole derivatives 0,2083
P02CA01 Mebendazole(O) 18001 g 0,2 g 0,1856
P02CA03 Albendazole(O) 4400 g 0,4 g 0,0227
P02CF Avermectines 0,0003
P02CF01 Ivermectin(O) 1,746 g 12 mg 0,0003
P03 ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES
AND REPELLENTS
P03A ECTOPARASITICIDES, INCL. SCABICIDES
P03AC Pyrethrines, incl. synthetic compounds
P03AC04 Permethrin(C) 74760 g
P03AX Other ectoparasiticides, incl. scabicides
P03AX01 Benzyl benzoate(C) 351330 g
R RESPIRATORY SYSTEM 91,8504
R01 NASAL PREPARATIONS 36,2791
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS
FOR TOPICAL USE 34,1838
R01AA Sympathomimetics, plain 22,0028
R01AA05 Oxymetazoline(N) 281,8575 g 0,4 mg 1,4530
R01AA07 Xylometazoline(N) 7972,5 g 0,8 mg 20,5498
R01AB Sympathomimetics, combinations excl. corticosteroids 3,0514
R01AB83 Xylometazoline+Ipratropium bromide(N) 193840 ml 0,8 ml 0,4996
R01AB85 Xylometazoline+Dexpanthenol(N) 989980 ml 0,8 ml 2,5518
R01AC Antiallergic agents, excl. corticosteroids 0,3533
R01AC03 Azelastine(N) 95,94 g 0,56 mg 0,3533
R01AD Corticosteroids 8,7763
R01AD01 Beclometasone(N) 6,31 g 0,4 mg 0,0325
R01AD05 Budesonide(N) 37,4907 g 0,2 mg 0,3865
R01AD08 Fluticasone(N) 84,759 g 0,2 mg 0,8739
35/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R01AD09 Mometasone(N) 370,468 g 0,2 mg 3,8197
R01AD12 Fluticasone furoate(N) 168,9567 g 0,11 mg 3,1673
R01AD81 Fluticasone+Azelastine(N) 963000 doses 4 doses 0,4964
R01AX Other nasal preparations
R01AX06 Mupirocin(N) 120 g
R01AX83 Retinol+Tocopherol(N) 142880 ml
R01B NASAL DECONGESTANTS FOR SYSTEMIC USE 2,0952
R01BA Sympathomimetics 2,0952
R01BA02 Pseudoephedrine(O) 140291,52 g 0,24 g 1,2054
R01BA81 Pseudoephedrine+Triprolidine(O) 28360,68 g 0,24 g 0,2437
R01BA84 Pseudoephedrine+Guaifenesin(O) 9138,6 g 0,24 g 0,0785
R01BA89 Pseudoephedrine+Loratadine(O) 10970,4 g 0,24 g 0,0943
R01BA93 Pseudoephedrine+Cetirizine(O) 55100,64 g 0,24 g 0,4734
R02 THROAT PREPARATIONS 2,7242
R02A THROAT PREPARATIONS 2,7242
R02AA Antiseptics 2,2405
R02AA06 Cetylpyridinium chloride(O) 18324 pieces
R02AA82 Benzydamine+Cetylpyridinium chloride(O) 852720 ml
R02AA82 Benzydamine+Cetylpyridinium chloride(O) 2008368 pieces 6 pieces 0,6902
R02AA89 Povidone, iodinated+Allantoin(O) 327330 ml
R02AA92 Dequalinium+Cinchocaine(O) 1115720 pieces 6 pieces 0,3834
R02AA94 Amylmetacresol+Dichlorobenzyl alcohol(O) 961920 pieces 6 pieces 0,3306
R02AA95 Amylmetacresol+Dichlorobenzyl alcohol+Levomenthol(O) 1664472 pieces 6 pieces 0,5720
R02AA96 Amylmetacresol+Dichlorobenzyl alcohol+Ascorbic acid(O) 641376 pieces 6 pieces 0,2204
R02AA98 Cetylpyridinium chloride+Benzocaine(O) 127458 pieces 6 pieces 0,0438
R02AD Anesthetics, local 0,1260
R02AD80 Lidocaine+Propyl parahydroxybenzoate(O) 366660 pieces 6 pieces 0,1260
R02AX Other throat preparations 0,3577
R02AX01 Flurbiprofen(O) 7631,89 g 44 mg 0,3577
R02AX80 Thyme herb+Sage leaf(O) 30150 ml
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES 28,0422
R03A ADRENERGICS, INHALANTS 20,4007
R03AC Selective beta-2-adrenoceptor agonists 3,9206
R03AC02 Salbutamol(I) 984,42 g 0,8 mg 2,5374
R03AC02 Salbutamol(I) 1286 g 0,01 g 0,2652
R03AC04 Fenoterol(I) 62,38 g 0,6 mg 0,2144
R03AC12 Salmeterol(I) 4,638 g 0,1 mg 0,0956
R03AC13 Formoterol(I) 5,7728 g 0,024 mg 0,4960
R03AC18 Indacaterol(I) 22,6935 g 0,15 mg 0,3120
R03AK Adrenergics in combination with corticosteroids or other drugs,
excl. anticholinergics 12,6544
R03AK06 Salmeterol+Fluticasone(I) 576480 doses 4 doses 0,2972
R03AK06 Salmeterol+Fluticasone(I) 2395860 doses 2 doses 2,4702
R03AK07 Formoterol+Budesonide(I) 1105440 doses 2 doses 1,1397
R03AK07 Formoterol+Budesonide(I) 6400680 doses 4 doses 3,2997
R03AK08 Formoterol+Beclometasone(I) 3452760 doses 4 doses 1,7800
R03AK10 Vilanterol+Fluticasone furoate(I) 1739040 doses 1 doses 3,5860
R03AK13 Salbutamol+Beclometasone(I) 158400 doses 4 doses 0,0817
R03AL Adrenergics in combinations with anticholinergics incl. triple
combinations with corticosteroids 3,8256
R03AL01 Fenoterol+Ipratropium bromide(I) 205720 ml 16 ml 0,0265
R03AL01 Fenoterol+Ipratropium bromide(I) 2713600 doses 6 doses 0,9326
R03AL03 Vilanterol+Umeclidinium(I) 355590 doses 1 doses 0,7333
R03AL04 Indacaterol+Glycopyrronium(I) 191370 doses 1 doses 0,3946
R03AL05 Formoterol+Aclidinium(I) 369240 doses 2 doses 0,3807
R03AL06 Olodaterol+Tiotropium(I) 699120 doses 2 doses 0,7208
R03AL07 Formoterol+Glycopyrronium(I) 195120 doses 4 doses 0,1006
R03AL08 Vilanterol+Umeclidinium+Fluticasone furoate(I) 72990 doses 1 doses 0,1505
R03AL09 Formoterol+Glycopyrronium+Beclometasone(I) 748800 doses 4 doses 0,3860
36/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES,
INHALANTS 4,7057
R03BA Glucocorticoids 1,5566
R03BA02 Budesonide(I) 149,2 g 1,5 mg 0,2051
R03BA02 Budesonide(I) 305,864 g 0,8 mg 0,7884
R03BA05 Fluticasone(I) 163,857 g 0,6 mg 0,5631
R03BB Anticholinergics 3,1491
R03BB01 Ipratropium bromide(I) 21,108 g 0,12 mg 0,3627
R03BB01 Ipratropium bromide(I) 21,625 g 0,3 mg 0,1486
R03BB04 Tiotropium(I) 3,4729 g 0,005 mg 1,4323
R03BB05 Aclidinium(I) 136,8242 g 0,644 mg 0,4381
R03BB06 Glycopyrronium(I) 7,4712 g 44 mcg 0,3501
R03BB07 Umeclidinium(I) 11,1276 g 55 mcg 0,4172
R03C ADRENERGICS FOR SYSTEMIC USE 0,0872
R03CC Selective beta-2-adrenoceptor agonists 0,0872
R03CC02 Salbutamol(O) 507,06 g 0,012 g 0,0871
R03CC02 Salbutamol(P) 0,327 g 0,012 g 0,0001
R03D OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY
DISEASES 2,8486
R03DA Xanthines 1,1525
R03DA04 Theophylline(O) 219340 g 0,4 g 1,1307
R03DA05 Aminophylline(O) 22,5 g 0,1 g 0,0005
R03DA05 Aminophylline(O) 36 g 0,6 g 0,0001
R03DA05 Aminophylline(P) 6174,8 g 0,6 g 0,0212
R03DC Leukotriene receptor antagonists 1,6247
R03DC03 Montelukast(O) 7878,808 g 0,01 g 1,6247
R03DX Other systemic drugs for obstructive airway diseases 0,0714
R03DX05 Omalizumab(P) 224,1 g 0,016 g 0,0289
R03DX07 Roflumilast(O) 0,18 g 0,5 mg 0,0007
R03DX09 Mepolizumab(P) 40,5 g 3,6 mg 0,0232
R03DX10 Benralizumab(P) 4,86 g 0,54 mg 0,0186
R05 COUGH AND COLD PREPARATIONS 6,8646
R05C EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH
SUPPRESSANTS 6,7464
R05CA Expectorants 0,0644
R05CA03 Guaifenesin(O) 28116 g 0,9 g 0,0644
R05CA12 Hederae helicis folium(O) 216938 pieces
R05CA12 Hederae helicis folium(O) 5806120 ml
R05CA86 Iceland moss(O) 6406500 ml
R05CA87 Distillate of rectified essential oils of eucalyptus, sweet orange,
myrtle and lemon(O) 1122820 pieces
R05CA88 Thyme herb+Wild thyme+Plantain(O) 320800 ml
R05CA89 Thyme herb+Hederae helicis folium(O) 248400 ml
R05CA91 Thyme herb+Marshmallow root(O) 183940 pieces
R05CA91 Thyme herb+Marshmallow root(O) 3851760 ml
R05CA92 Thyme herb(O) 162660 pieces
R05CB Mucolytics 6,6820
R05CB01 Acetylcysteine(I, P) 225 g
R05CB01 Acetylcysteine(O) 985524,8 g 0,5 g 4,0644
R05CB01 Acetylcysteine(P) 7968 g
R05CB02 Bromhexine(O) 7499,12 g 0,024 g 0,6443
R05CB03 Carbocisteine(O) 136752,5 g 1,5 g 0,1880
R05CB06 Ambroxol(O) 102684,75 g 0,12 g 1,7645
R05CB13 Dornase alfa(I) 25,14 g 2,5 mg 0,0207
R05D COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH
EXPECTORANTS 0,0759
R05DB Other cough suppressants 0,0759
R05DB09 Oxeladin(O) 2945,75 g 0,08 g 0,0759
R05F COUGH SUPPRESSANTS AND EXPECTORANTS,
COMBINATIONS 0,0422
R05FA Opium derivatives and expectorants 0,0422
37/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R05FA80 Codeine+Guaifenesin(O) 614250 ml 30 ml 0,0422
R05X OTHER COLDPREPARATIONS
R05XA Other cold combination preparations
R05XA80 Gentian root+Primula flower+Common sorrel+Elder
flower+Verbena herb(O) 3102,4 g
R05XA80 Gentian root+Primula flower+Common sorrel+Elder
flower+Verbena herb(O) 1401770 pieces
R05XA82 Ibuprofen+Pseudoephedrine(O) 5733,6 g
R06 ANTIHISTAMINES FOR SYSTEMIC USE 17,9399
R06A ANTIHISTAMINES FOR SYSTEMIC USE 17,9399
R06AA Aminoalkyl ethers 0,4810
R06AA02 Diphenhydramine(O) 19 g 0,2 g 0,0002
R06AA02 Diphenhydramine(P) 30,1 g
R06AA04 Clemastine(O) 425,96 g 0,002 g 0,4392
R06AA04 Clemastine(P) 40,4 g 0,002 g 0,0417
R06AE Piperazine derivatives 8,9059
R06AE07 Cetirizine(O) 40804,27 g 0,01 g 8,4141
R06AE09 Levocetirizine(O) 1192,55 g 0,005 g 0,4918
R06AX Other antihistamines for systemic use 8,5530
R06AX02 Cyproheptadine(O) 0,12 g 0,012 g <0,0001
R06AX13 Loratadine(O) 18549,3 g 0,01 g 3,8250
R06AX15 Mebhydrolin(O) 10 g 0,2 g 0,0001
R06AX17 Ketotifen(O) 1,32 g 0,002 g 0,0014
R06AX22 Ebastine(O) 7202,1 g 0,01 g 1,4851
R06AX27 Desloratadine(O) 2485,37 g 0,005 g 1,0250
R06AX28 Rupatadine(O) 941,12 g 0,01 g 0,1941
R06AX29 Bilastine(O) 19614,2 g 20 mg 2,0223
R07 OTHER RESPIRATORY SYSTEM PRODUCTS 0,0004
R07A OTHER RESPIRATORY SYSTEM PRODUCTS 0,0004
R07AA Lung surfactants 0,0004
R07AA81 Porcine lung phospholipids(endotrach) 33,48 g 0,16 g 0,0004
S SENSORY ORGANS 32,8766
S01 OPHTHALMOLOGICALS 32,8766
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA01 Chloramphenicol(S) 168710 ml
S01AA02 Chlortetracycline(S) 0,75 g
S01AA12 Tobramycin(S) 34485 ml
S01AA12 Tobramycin(S) 47820,5 g
S01AA13 Fusidic acid(S) 35950 g
S01AD Antivirals
S01AD02 Trifluridine(S) 5 ml
S01AD03 Aciclovir(S) 3159 g
S01AE Fluoroquinolones
S01AE03 Ciprofloxacin(S) 12430 ml
S01AE05 Levofloxacin(S) 25485 ml
S01AE07 Moxifloxacin(S) 15465 ml
S01AX Other antiinfectives
S01AX15 Propamidine(S) 130 ml
S01AX18 Povidone, iodinated(S) 472 ml
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA01 Dexamethasone(S) 162 pieces
S01BA01 Dexamethasone(S) 15035,6 g
S01BA01 Dexamethasone(S) 142710 ml
S01BA02 Hydrocortisone(S) 4206 g
S01BA09 Clobetasone(S) 12500 ml
S01BA14 Loteprednol(S) 1305 ml
S01BC Antiinflammatory agents, non-steroids
S01BC03 Diclofenac(S) 30 ml
S01BC05 Ketorolac(S) 11500 ml
38/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
S01BC10 Nepafenac(S) 19645 ml
S01BC11 Bromfenac(S) 12760 ml
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN
COMBINATION
S01CA Corticosteroids and antiinfectives in combination
S01CA80 Dexamethasone+Neomycin+Polymyxin B(S) 43670 ml
S01CA81 Dexamethasone+Tobramycin(S) 13639,5 g
S01CA81 Dexamethasone+Tobramycin(S) 37545 ml
S01CA82 Dexamethasone+Chloramphenicol(S) 47792,5 g
S01CA82 Dexamethasone+Chloramphenicol(S) 434070 ml
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS 32,8766
S01EA Sympathomimetics in glaucoma therapy 0,0516
S01EA05 Brimonidine(S) 5000 ml 0,2 ml 0,0516
S01EB Parasympathomimetics 0,0150
S01EB01 Pilocarpine(S) 2225 ml 0,4 ml 0,0115
S01EB02 Carbachol(S) 690 ml 0,4 ml 0,0036
S01EB09 Acetylcholine chloride(S) 0,2 g
S01EC Carbonic anhydrase inhibitors 3,7275
S01EC01 Acetazolamide(O) 26335 g 0,75 g 0,0724
S01EC01 Acetazolamide(P) 97 g 0,75 g 0,0003
S01EC03 Dorzolamide(S) 140115 ml 0,3 ml 0,9631
S01EC04 Brinzolamide(S) 163050 ml 0,2 ml 1,6811
S01EC80 Brinzolamide+Brimonidine(S) 98025 ml 0,2 ml 1,0107
S01ED Beta blocking agents 20,5307
S01ED01 Timolol(S) 20510 ml 0,2 ml 0,2115
S01ED01 Timolol(S) 226900 g 40 mg 11,6971
S01ED02 Betaxolol(S) 83585 ml 0,2 ml 0,8618
S01ED80 Timolol+Dorzolamide(S) 295210 ml 0,2 ml 3,0437
S01ED81 Timolol+Travoprost(S) 41442,5 ml 0,2 ml 0,4273
S01ED82 Timolol+Bimatoprost(S) 110142 ml 0,2 ml 1,1356
S01ED83 Timolol+Brinzolamide(S) 224240 ml 0,2 ml 2,3120
S01ED84 Timolol+Latanoprost(S) 73267,5 ml 0,2 ml 0,7554
S01ED85 Timolol+Tafluprost(S) 8377,8 ml 0,2 ml 0,0864
S01EE Prostaglandin analogues 8,5518
S01EE01 Latanoprost(S) 269522,5 ml 0,1 ml 5,5577
S01EE03 Bimatoprost(S) 276 ml 0,1 ml 0,0057
S01EE04 Travoprost(S) 64497,5 ml 0,1 ml 1,3300
S01EE05 Tafluprost(S) 241272 ml 0,3 ml 1,6584
S01F MYDRIATICS AND CYCLOPLEGICS
S01FA Anticholinergics
S01FA01 Atropine(S) 640 ml
S01FA04 Cyclopentolate(S) 26520 ml
S01FA06 Tropicamide(S) 13150 ml
S01FB Sympathomimetics excl. antiglaucoma preparations
S01FB01 Phenylephrine(S) 6270 ml
S01G DECONGESTANTS AND ANTIALLERGICS
S01GA Sympathomimetics used as decongestants
S01GA02 Tetryzoline(S) 260730 ml
S01GX Other antiallergics
S01GX01 Cromoglicic acid(S) 103170 ml
S01GX07 Azelastine(S) 39960 ml
S01GX09 Olopatadine(S) 22255 ml
S01H LOCAL ANESTHETICS
S01HA Local anesthetics
S01HA03 Tetracaine(S) 25390 ml
S01HA04 Proxymetacaine(S) 33285 ml
S01J DIAGNOSTIC AGENTS
S01JA Colouring agents
S01JA01 Fluorescein(P) 4500 ml
S01JA81 Fluorescein+Oxybuprocaine+Chlorobutanol(S) 2650 ml
S01K SURGICAL AIDS
39/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
S01KA Viscoelastic substances
S01KA02 Hypromellose(S) 5250 g
S01L OCULAR VASCULAR DISORDER AGENTS
S01LA Antineovascularisation agents
S01LA01 Verteporfin(P) 2 pieces
S01LA04 Ranibizumab(S) 1 pieces
S01LA05 aflibercept(S) 191 pieces
S01X OTHER OPHTHALMOLOGICALS
S01XA Other ophthalmologicals
S01XA03 Sodium chloride(S) 227,5 g
S01XA18 Ciclosporin(S) 4671 ml
S01XA80 Retinol+Dexpanthenol(S) 8172,5 g
S01XA81 Carbomer(S) 196380 g
S01XA82 Hypromellose(S) 169750 ml
S01XA85 Hypromellose+Dextran(S) 353100 ml
S02 OTOLOGICALS
S02C CORTICOSTEROIDS AND ANTIINFECTIVES IN
COMBINATION
S02CA Corticosteroids and antiinfectives in combination
S02CA81 Dexamethasone+Neomycin+Acetic acid, glacial(A) 3770 ml
S02CA82 Hydrocortisone+Ciprofloxacin(A) 131210 ml
S02D OTHER OTOLOGICALS
S02DA Analgesics and anesthetics
S02DA81 Phenazone+Lidocaine(A) 1530 ml
T HERBAL MEDICINAL PRODUCTS
T01 HERBAL MEDICINAL PRODUCTS
T01R HERBAL MEDICINAL PRODUCTS
T01RS Herbal medicinal products
T01RS01 herbal preparation(O) 676890 pieces
T01RS01 herbal preparation(O) 7993240 ml
T01RS02 homeopathic preparations(A) 5470 ml
T01RS02 homeopathic preparations(C) 549650 g
T01RS02 homeopathic preparations(O) 1680 g
T01RS02 homeopathic preparations(O) 1124710 ml
T01RS02 homeopathic preparations(O) 1270430 pieces
T01RS02 homeopathic preparations(R) 12 pieces
V VARIOUS 0,2149
V01 ALLERGENS
V01A ALLERGENS
V01AA Allergen extracts
V01AA02 Grass pollen(O) 151 pieces
V01AA02 Grass pollen(P) 165 pieces
V01AA03 House dust mites(O) 264 pieces
V01AA03 House dust mites(P) 12 ml
V01AA03 House dust mites(P) 285 pieces
V01AA05 Tree pollen(P) 495 pieces
V01AA05 Tree pollen(SL) 642 pieces
V01AA07 Allergen products (insects)(P) 534 pieces
V01AA11 Animals(O) 39 pieces
V01AA80 Tree and grass pollen(O) 111 pieces
V01AA80 Tree and grass pollen(P) 99 pieces
V01AA83 Grass pollen+Flowers(O) 5 pieces
V01AA84 Tree and flower pollen(O) 12 pieces
V03 ALL OTHER THERAPEUTIC PRODUCTS 0,2149
V03A ALL OTHER THERAPEUTIC PRODUCTS 0,2149
V03AB Antidotes
V03AB06 Sodium thiosulphate(P) 450 g
V03AB09 Dimercaprol(P) 4,8 g
V03AB14 Protamine sulfate(P) 285 g
V03AB15 Naloxone(N) 3,6 g
V03AB15 Naloxone(P) 2,272 g
40/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
V03AB16 Ethanol(P) 10900 ml
V03AB17 Methylthioninium chloride(P) 173 g
V03AB19 Physostigmine(P) 0,06 g
V03AB21 Potassium iodide(O) 13 g
V03AB24 Digitalis antitoxin(P) 3,44 g
V03AB25 Flumazenil(P) 0,29 g
V03AB33 Hydroxocobalamin(P) 80 g
V03AB34 Fomepizole(P) 20 g
V03AB35 Sugammadex(P) 104 g
V03AB37 Idarucizumab(P) 270 g
V03AB80 Sodium calcium edetate(P) 40 g
V03AC Iron chelating agents
V03AC01 Deferoxamine(P) 50 g
V03AC03 Deferasirox(O) 7695 g
V03AE Drugs for treatment of hyperkalemia and hyperphosphatemia 0,1501
V03AE01 Polystyrene sulfonate(O, R) 1826350,5 g 45 g 0,0837
V03AE02 Sevelamer(O) 155664 g 6,4 g 0,0502
V03AE03 Lanthan(O) 17752,5 g 2,25 g 0,0163
V03AF Detoxifying agents for antineoplastic treatment 0,0647
V03AF01 Mesna(P) 4188 g
V03AF03 Calcium folinate(O) 30,6 g 0,06 g 0,0011
V03AF07 Rasburicase(P) 0,738 g 0,014 g 0,0001
V03AF09 Glucarpidase(P) 19000 U
V03AF10 Sodium levofolinate(P) 925 g 0,03 g 0,0636
V03AH Drugs for treatment of hypoglycemia
V03AH01 Diazoxide(O) 60 g
V03AN Medical gases
V03AN01 Oxygen(I) 486681000 ml
V03AN05 Air, medicinal(I) 2840000 ml
V04 DIAGNOSTIC AGENTS
V04C OTHER DIAGNOSTIC AGENTS
V04CD Tests for pituitary function
V04CD04 Corticorelin(P) 0,0004 g
V04CF Tuberculosis diagnostics
V04CF01 Tuberculin(P) 9630 U
V04CJ Tests for thyreoidea function
V04CJ02 Protirelin(P) 0,004 g
V04CX Other diagnostic agents
V04CX01 Indocyanine green(P) 1,15 g
V04CX03 Methacholine(I) 51,708 g
V04CX04 Mannitol(I) 14,605 g
V04CX04 Mannitol(I) 80 pieces
V04CX06 Hexaminolevulinate(P) 20,145 g
V04CX09 Patent blue(P) 5 g
V04CX87 Carbon monoxide+Helium(I) 20000 ml
V07 ALL OTHER NON-THERAPEUTIC PRODUCTS
V07A ALL OTHER NON-THERAPEUTIC PRODUCTS
V07AB Solvents and diluting agents, incl. irrigating solutions
V07AB80 Sodium chloride(P) 7065500 ml
V07AB83 Water for injection(NA) 16928200 ml
V08 CONTRAST MEDIA
V08A X-RAY CONTRAST MEDIA, IODINATED
V08AA Watersoluble, nephrotropic, high osmolar X-ray contrast media
V08AA01 Sodium amidotrizoate+Meglumine Amidotrizoate(P) 6000 ml
V08AB Watersoluble, nephrotropic, low osmolar X-ray contrast media
V08AB02 Iohexol(P) 1657574,5 g
V08AB05 Iopromide(P) 1186640 g
V08AB09 Iodixanol(P) 2849386 g
41/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
V08AD Non-watersoluble X-ray contrast media
V08AD01 Ethyl esters of iodised fatty acids(P) 96 g
V08B X-RAY CONTRAST MEDIA, NON-IODINATED
V08BA Barium sulfate containing X-ray contrast media
V08BA01 Barium sulfate(O) 192520,72 g
V08C MAGNETIC RESONANCE IMAGING CONTRAST MEDIA
V08CA Paramagnetic contrast media
V08CA01 Gadopentetic acid(P) 4460 ml
V08CA02 Gadoteric acid(P) 54450 ml
V08CA09 Gadobutrol(P) 85447,5 ml
V08CA10 Gadoxetic acid(P) 5670 ml
V08D ULTRASOUND CONTRAST MEDIA
V08DA Ultrasound contrast media
V08DA05 Sulfur hexafluoride, phospholipid microspheres(P) 100 ml
V09 DIAGNOSTIC RADIOPHARMACEUTICALS
V09A CENTRAL NERVOUS SYSTEM
V09AB Iodine (123I) compounds
V09AB03 Ioflupane (123I)(P) 430 ml
V09F THYROID
V09FX Various thyroid diagnostic radiopharmaceuticals
V09FX01 Technetium (99mTc) pertechnetate(S) 30 pieces
V10 THERAPEUTIC RADIOPHARMACEUTICALS
V10X OTHER THERAPEUTIC RADIOPHARMACEUTICALS
V10XA Iodine (131I) compounds
V10XA01 Sodium iodide (131I)(O) 65 pieces
42/42
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A ALIMENTARY TRACT AND METABOLISM 188,4400
A01 STOMATOLOGICAL PREPARATIONS 0,0703
A01A STOMATOLOGICAL PREPARATIONS 0,0703
A01AB Antiinfectives and antiseptics for local oral treatment 0,0703
A01AB09 Miconazole (O) 6820,8 g 0,2 g 0,0703
A01AB12 Hexetidine (O) 1321280 ml
A01AB82 Demeclocycline+Triamcinolone (dental) 465 g
A01AD Other agents for local oral treatment
A01AD80 Lidocaine+Cetylpyridinium chloride (gingival) 221300 g
A01AD81 Lidocaine+Cetrimide (O) 64265 g
A01AD82 Choline salicylate (O) 403808 pieces
A01AD83 Lidocaine+Chamomille extract (O) 347870 g
A02 DRUGS FOR ACID RELATED DISORDERS 62,6277
A02A ANTACIDS 1,1306
A02AD Combinations and complexes of aluminium, calcium and
magnesium compounds 1,1306
A02AD81 Aluminium hydroxide+Magnesium hydroxide (O) 1227440 pieces 10 pieces 0,2528
A02AD81 Aluminium hydroxide+Magnesium hydroxide (O) 5263316 ml 50 ml 0,2168
A02AD83 Calcium carbonate+Magnesium carbonate (O) 3208344 pieces 10 pieces 0,6609
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-
OESOPHAGEAL REFLUX DISEASE (GORD) 61,4971
A02BA H2-receptor antagonists 0,0430
A02BA02 Ranitidine (P) 2757 g 0,3 g 0,0189
A02BA03 Famotidine (O) 468 g 0,04 g 0,0241
A02BC Proton pump inhibitors 61,4401
A02BC01 Omeprazole (O) 300792,74 g 0,02 g 30,9808
A02BC02 Pantoprazole (O) 320357,94 g 0,04 g 16,4980
A02BC02 Pantoprazole (P) 19,6 g 0,04 g 0,0010
A02BC03 Lansoprazole (O) 7,98 g 0,03 g 0,0005
A02BC04 Rabeprazole (O) 15,68 g 0,02 g 0,0016
A02BC05 Esomeprazole (O) 198885,96 g 0,03 g 13,6565
A02BC05 Esomeprazole (P) 4393,6 g 0,03 g 0,3017
A02BC08 Vonoprazan (O) 8 g
A02BD Combinations for eradication of Helicobacter pylori 0,0019
A02BD08 Bismuth subcitrate+Tetracycline+Metronidazole (O) 11160 pieces 12 pieces 0,0019
A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux
disease (GORD) 0,0120
A02BX02 Sucralfate (O) 23340 g 4 g 0,0120
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL
DISORDERS 8,8152
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL
DISORDERS 7,8830
A03AA Synthetic anticholinergics, esters with tertiary amino group 1,4006
A03AA04 Mebeverine (O) 203982 g 0,3 g 1,4006
A03AB Synthetic anticholinergics, quaternary ammonium compounds 0,0002
A03AB02 Glycopyrronium (P) 0,027 g 0,3 mg 0,0002
A03AD Papaverine and derivatives 4,8961
A03AD01 Papaverine hydrochloride (P) 20 g 0,1 g 0,0004
A03AD02 Drotaverine (O) 234638,08 g 0,1 g 4,8334
A03AD02 Drotaverine (P) 3022 g 0,1 g 0,0623
A03AX Other drugs for functional gastrointestinal disorders 1,5861
A03AX13 Simeticone (O) 384996,15 g 0,5 g 1,5861
A03B BELLADONNA AND DERIVATIVES, PLAIN 0,0744
A03BA Belladonna alkaloids, tertiary amines 0,0647
A03BA01 Atropine (O, P) 18,25 g 0,0015 g 0,0251
A03BA01 Atropine (P) 28,88 g 0,0015 g 0,0397
A03BB Belladonna alkaloids, semisynthetic, quaternary ammonium
compounds 0,0096
A03BB01 Hyoscine butylbromide (O) 1,8 g 0,06 g 0,0001
A03BB01 Hyoscine butylbromide (P) 278,8 g 0,06 g 0,0096
A03F PROPULSIVES 0,8578
1/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A03FA Propulsives 0,8578
A03FA01 Metoclopramide (O) 10650,5 g 0,03 g 0,7313
A03FA01 Metoclopramide (P) 1601,3 g 0,03 g 0,1100
A03FA03 Domperidone (O) 240,6 g 0,03 g 0,0165
A04 ANTIEMETICS AND ANTINAUSEANTS 0,1251
A04A ANTIEMETICS AND ANTINAUSEANTS 0,1251
A04AA Serotonin (5-HT3) antagonists 0,1169
A04AA01 Ondansetron (P) 192,36 g 0,016 g 0,0248
A04AA02 Granisetron (O) 63,73 g 0,002 g 0,0656
A04AA02 Granisetron (P) 35,5 g 0,003 g 0,0244
A04AA05 Palonosetron (P) 0,0025 g 0,25 mg <0,0001
A04AA80 Palonosetron+Netupitant (O) 1020 pieces 1 pieces 0,0021
A04AD Other antiemetics 0,0082
A04AD01 Scopolamine (TD) 5 pieces 1 pieces <0,0001
A04AD12 Aprepitant (O) 219,735 g 0,165 g 0,0027
A04AD81 Fosaprepitant (P) 251,7 g 0,095 g 0,0055
A05 BILE AND LIVER THERAPY 1,9950
A05A BILE THERAPY 0,5801
A05AA Bile acids and derivatives 0,5801
A05AA02 Ursodeoxycholic acid (O) 211225 g 0,75 g 0,5801
A05B LIVER THERAPY, LIPOTROPICS 1,4149
A05BA Liver therapy 1,4149
A05BA03 Silymarin (O) 1955410 pieces
A05BA03 Silymarin (P) 56 g
A05BA80 Phospholipids from Soya Beans (O) 1368450 pieces 3 pieces 0,9396
A05BA80 Phospholipids from Soya Beans (O) 1384250 pieces 6 pieces 0,4752
A05BA80 Phospholipids from Soya Beans (P) 605 pieces
A06 DRUGS FOR CONSTIPATION 17,4337
A06A DRUGS FOR CONSTIPATION 17,4337
A06AB Contact laxatives 7,6130
A06AB02 Bisacodyl (O) 14106,4 g 0,01 g 2,9058
A06AB02 Bisacodyl (R) 160,82 g 0,01 g 0,0331
A06AB06 Senna glycosides (O) 2480 pieces 1 pieces 0,0051
A06AB08 Sodium picosulfate (O) 11324,937 g 0,005 g 4,6657
A06AB80 Sodium picosulfate+Magnesium oxide+Citric acid (O) 3080 pieces 2 pieces 0,0032
A06AD Osmotically acting laxatives 8,7400
A06AD11 Lactulose (O) 26717524,2 g 6,7 g 8,2144
A06AD15 Macrogol (O) 2551560 g 10 g 0,5256
A06AD80 Macrogol+Sodium citrate+Citric acid+Sodium
chloride+Potassium chloride (O) 17000 ml
A06AD81 Sodium sulphate, anhydrous+Potassium chloride+Sodium
chloride+Macrogol+Sodium hydrogen carbonate (O) 32936 pieces
A06AD83
Macrogol+Sodium sulphate, anhydrous+Sodium
chloride+Potassium chloride+Ascorbic acid+Sodium ascorbate
(O)
6412 pieces
A06AD85 Sodium sulphate, anhydrous+magnesium sulfate
heptahydrate+Potassium sulphate (O) 720896 ml
A06AG Enemas 1,0292
A06AG11 Laurilsulfate, incl. combinations+Sorbitol+Sodium citrate (R) 499608 pieces 1 pieces 1,0292
A06AH Peripheral opioid receptor antagonists 0,0515
A06AH03 Naloxegol (O) 624,75 g 25 mg 0,0515
A06AX Other drugs for constipation
A06AX81 Sodium hydrogen carbonate+Potassium hydrogentartrate (R) 120 pieces
A07 ANTIDIARRHEALS, INTESTINAL
ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS 4,3086
A07A INTESTINAL ANTIINFECTIVES 0,0054
A07AA Antibiotics 0,0054
A07AA02 Nystatin (O) 100000000 U 1500000 U 0,0001
A07AA11 Rifaximin (O) 1536 g 0,6 g 0,0053
A07B INTESTINAL ADSORBENTS 0,3805
A07BC Other intestinal adsorbents 0,3805
A07BC05 Diosmectidum (O) 1662420 g 9 g 0,3805
2/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A07C ELECTROLYTES WITH CARBOHYDRATES
A07CA Oral rehydration salt formulations
A07CA80 Sodium chloride+Potassium chloride+Sodium citrate+Glucose
(O) 86920 pieces
A07D ANTIPROPULSIVES 0,9125
A07DA Antipropulsives 0,9125
A07DA03 Loperamide (O) 4429,652 g 0,01 g 0,9125
A07E INTESTINAL ANTIINFLAMMATORY AGENTS 2,4140
A07EA Corticosteroids acting locally 0,0271
A07EA06 Budesonide (O) 118,29 g 0,009 g 0,0271
A07EA06 Budesonide (R) 1,5694 g
A07EC Aminosalicylic acid and similar agents 2,3869
A07EC01 Sulfasalazine (O) 757500 g 2 g 0,7802
A07EC02 Mesalazine (O) 1072408 g 1,5 g 1,4727
A07EC02 Mesalazine (R) 97544 g 1,5 g 0,1340
A07F ANTIDIARRHEAL MICROORGANISMS 0,5962
A07FA Antidiarrheal microorganisms 0,5962
A07FA02 Saccharomyces boulardii (O) 289442,5 g 1 g 0,5962
A07X OTHER ANTIDIARRHEALS
A07XA Other antidiarrheals
A07XA04 Racecadotril (O) 2869,44 g
A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0503
A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0503
A08AA Centrally acting antiobesity products 0,0503
A08AA62 Bupropione+Naltrexone (O) 97664 pieces 4 pieces 0,0503
A09 DIGESTIVES, INCL. ENZYMES 1,8176
A09A DIGESTIVES, INCL. ENZYMES 1,8176
A09AA Enzyme preparations 1,8176
A09AA02 Lipase+Amylase+Protease (O) 3529492 pieces 4 pieces 1,8176
A10 DRUGS USED IN DIABETES 67,4826
A10A INSULINS AND ANALOGUES 15,3462
A10AB Insulins and analogues for injection, fast-acting 5,8915
A10AB01 Insulin (human) (P) 1339500 U 40 U 0,0690
A10AB04 Insulin lispro (P) 19329000 U 40 U 0,9954
A10AB05 Insulin aspart (P) 82717500 U 40 U 4,2598
A10AB06 Insulin glulisine (P) 11014500 U 40 U 0,5672
A10AC Insulins and analogues for injection, intermediate-acting 0,0485
A10AC01 Insulin (human) (P) 942000 U 40 U 0,0485
A10AD Insulins and analogues for injection, intermediate- or long-
acting combined with fast-acting 0,6543
A10AD04 Insulin lispro (P) 3465000 U 40 U 0,1784
A10AD05 Insulin aspart (P) 8764500 U 40 U 0,4514
A10AD06 Insulin degludec+Insulin aspart (P) 476000 U 40 U 0,0245
A10AE Insulins and analogues for injection, long-acting 8,7519
A10AE04 Insulin glargine (P) 91207500 U 40 U 4,6971
A10AE05 Insulin detemir (P) 33979500 U 40 U 1,7499
A10AE06 Insulin degludec (P) 41344200 U 40 U 2,1292
A10AE54 Insulin glargine+Lixisenatide (P) 3412500 U 40 U 0,1757
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS 52,1365
A10BA Biguanides 20,9501
A10BA02 Metformin (O) 20340486 g 2 g 20,9501
A10BB Sulfonylureas 11,2810
A10BB07 Glipizide (O) 767,1 g 0,01 g 0,1580
A10BB09 Gliclazide (O) 187531,8 g 0,06 g 6,4384
A10BB12 Glimepiride (O) 4548,27 g 0,002 g 4,6846
A10BD Combinations of oral blood glucose lowering drugs 7,9925
A10BD07 Metformin+Sitagliptin (O) 1512000 pieces 2 pieces 1,5573
A10BD08 Metformin+Vildagliptin (O) 1347660 pieces 2 pieces 1,3881
A10BD10 Metformin+Saxagliptin (O) 291720 pieces 2 pieces 0,3005
A10BD11 Metformin+Linagliptin (O) 1280520 pieces 2 pieces 1,3189
A10BD15 Metformin+Dapagliflozin (O) 1014944 pieces 2 pieces 1,0454
3/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A10BD19 Linagliptin+Empagliflozin (O) 217080 pieces 1 pieces 0,4472
A10BD20 Metformin+Empagliflozin (O) 1681260 pieces 2 pieces 1,7317
A10BD21 Saxagliptin+Dapagliflozin (O) 97944 pieces 1 pieces 0,2018
A10BD23 Metformin+Ertugliflozin (O) 896 pieces 1 pieces 0,0018
A10BF Alpha glucosidase inhibitors 0,0006
A10BF01 Acarbose (O) 89,25 g 0,3 g 0,0006
A10BG Thiazolidinediones 0,1295
A10BG03 Pioglitazone (O) 1886,22 g 0,03 g 0,1295
A10BH Dipeptyl peptidase 4 (DPP-4) inhibitors 4,1812
A10BH01 Sitagliptin (O) 39196,5 g 0,1 g 0,8074
A10BH02 Vildagliptin (O) 7593 g 0,1 g 0,1564
A10BH03 Saxagliptin (O) 504,9 g 5 mg 0,2080
A10BH05 Linagliptin (O) 7304,55 g 5 mg 3,0094
A10BJ Glucagon-like peptide-1 (GLP-1) analogues 4,1123
A10BJ01 Exenatide (P) 4,368 g 0,286 mg 0,0315
A10BJ02 Liraglutide (P) 482,796 g 1,5 mg 0,6630
A10BJ03 Lixisenatide (P) 0,3993 g 20 mcg 0,0411
A10BJ05 Dulaglutide (P) 34,104 g 0,16 mg 0,4391
A10BJ06 Semaglutide (O) 576,63 g 10,5 mg 0,1131
A10BJ06 Semaglutide (P) 150,827 g 0,11 mg 2,8245
A10BK Sodium-glucose co-transporter 2 (SGLT2) inhibitors 3,4891
A10BK01 Dapagliflozin (O) 7520,4 g 10 mg 1,5492
A10BK03 empagliflozin (O) 16477,05 g 17,5 mg 1,9395
A10BK04 Ertugliflozin (O) 1,96 g 10 mg 0,0004
A11 VITAMINS 14,0734
A11A MULTIVITAMINS, COMBINATIONS 1,3133
A11AA Multivitamins with minerals 1,3133
A11AA03 Multivitamins+Mineral elements (O) 637560 pieces 1 pieces 1,3133
A11C VITAMIN A AND D, INCL. COMBINATIONS OF THE TWO 5,3526
A11CA Vitamin A, plain <0,0001
A11CA01 Retinol (P) 600000 U 50000 U <0,0001
A11CC Vitamin D and analogues 5,3526
A11CC04 Calcitriol (O) 0,1299 g 0,001 mg 0,2676
A11CC05 Colecalciferol (O) 987400000 U 400 U 5,0850
A11CC05 Colecalciferol (P) 31000000 U
A11D VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN
B6 AND B12 1,5294
A11DA Vitamin B1, plain 0,4082
A11DA01 Thiamine (P) 9908,5 g 0,05 g 0,4082
A11DA03 Benfotiamine (O) 1689370 pieces
A11DB Vitamin B1 in combination with vitamin B6 and/or vitamin B12 1,1212
A11DB80 Thiamine+Pyridoxine (P) 3750 pieces 1 pieces 0,0077
A11DB81 Benfotiamine+Pyridoxine (O) 227520 pieces 3 pieces 0,1562
A11DB84 Thiamine+Pyridoxine+Cyanocobalamin (O) 401120 pieces 1 pieces 0,8263
A11DB85 Thiamine+Pyridoxine+Cyanocobalamin+Lidocaine (P) 63590 pieces 1 pieces 0,1310
A11E VITAMIN B-COMPLEX, INCL. COMBINATIONS 0,4707
A11EA Vitamin B-complex, plain 0,4707
A11EA80 Thiamine+Nicotinamide+Riboflavin+Calcium
pantothenate+Pyridoxine (O) 228500 pieces 1 pieces 0,4707
A11EA80 Thiamine+Nicotinamide+Riboflavin+Calcium
pantothenate+Pyridoxine (P) 1032 pieces
A11G ASCORBIC ACID (VITAMIN C), INCL. COMBINATIONS 0,1610
A11GA Ascorbic acid (vitamin C), plain 0,1610
A11GA01 Ascorbic acid (P) 15630 g 0,2 g 0,1610
A11H OTHER PLAIN VITAMIN PREPARATIONS 0,0511
A11HA Other plain vitamin preparations 0,0511
A11HA02 Pyridoxine (O) 150 g 0,16 g 0,0019
A11HA02 Pyridoxine (P) 3630,5 g 0,16 g 0,0467
A11HA03 Tocopherol (P) 4,5 g 0,2 g <0,0001
A11HA08 Tocofersolan (O) 234 g 0,2 g 0,0024
A11J OTHER VITAMIN PRODUCTS, COMBINATIONS 5,1952
A11JA Combinations of vitamins
4/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A11JA80 Combinations of vitamins (O) 700 ml
A11JB Vitamins with minerals 5,1952
A11JB81 Pyridoxine+Magnesium (O) 7469180 pieces 4 pieces 3,8465
A11JB82
Thiamine+Riboflavin+Pyridoxine+Cyanocobalamin+Ascorbic
acid+Biotin+Nicotinamide+Calcium
pantothenate+Calcium+Magnesium+Folic acid+Zinc (O)
654735 pieces 1 pieces 1,3487
A12 MINERAL SUPPLEMENTS 8,9740
A12A CALCIUM 5,4367
A12AA Calcium 0,9393
A12AA03 Calcium gluconate (P) 60410 g 3 g 0,0415
A12AA04 Calcium carbonate (O) 1307550 g 3 g 0,8978
A12AX Calcium, combinations with vitamin D and/or other drugs 4,4974
A12AX80 Calcium+Colecalciferol (O) 611880 pieces 1 pieces 1,2604
A12AX80 Calcium+Colecalciferol (O) 3142740 pieces 2 pieces 3,2369
A12B POTASSIUM 3,0981
A12BA Potassium 3,0981
A12BA01 Potassium chloride (O) 380400 g 3 g 0,2612
A12BA80 Potassium chloride+Potassium hydrogen carbonate (O) 10600 pieces
A12BA81 Potassium aspartate+Magnesium aspartate (O) 4094050 pieces 3 pieces 2,8112
A12BA81 Potassium aspartate+Magnesium aspartate (P) 12490 pieces 1 pieces 0,0257
A12C OTHER MINERAL SUPPLEMENTS 0,4392
A12CC Magnesium 0,4392
A12CC04 Magnesium citrate (O) 426425,192 g 2 g 0,4392
A12CX Other mineral products
A12CX83 Phosphate (O) 12200 pieces
A14 ANABOLIC AGENTS FOR SYSTEMIC USE 0,0025
A14A ANABOLIC STEROIDS 0,0025
A14AB Estren derivatives 0,0025
A14AB01 Nandrolone (P) 2,4 g 0,002 g 0,0025
A16 OTHER ALIMENTARY TRACT AND METABOLISM
PRODUCTS 0,6640
A16A OTHER ALIMENTARY TRACT AND METABOLISM
PRODUCTS 0,6640
A16AA Amino acids and derivatives 0,0021
A16AA01 Levocarnitine (O) 2070 g 2 g 0,0021
A16AA02 Ademetionine (O) 900 g
A16AA02 Ademetionine (P) 50 g
A16AA81 Glycine (O) 390 g
A16AB Enzymes 0,0046
A16AB03 Agalsidase alfa (P) 1,337 g 0,001 g 0,0028
A16AB04 Agalsidase beta (P) 1,625 g 0,005 g 0,0007
A16AB07 Alglucosidase alfa (P) 57,5 g 0,1 g 0,0012
A16AB09 Idursulfase (P) 1,344 g
A16AX Various alimentary tract and metabolism products 0,6573
A16AX01 Thioctic acid (O) 187506 g 0,6 g 0,6438
A16AX01 Thioctic acid (P) 342 g 0,6 g 0,0012
A16AX03 Sodium phenylbutyrate (O) 1250 g 20 g 0,0001
A16AX05 Zinc (O) 700 g 0,15 g 0,0096
A16AX07 Sapropterin (O) 876 g
A16AX10 Eliglustat (O) 211,68 g 0,168 g 0,0026
A16AX80 Creatine (O) 450 g
A16AX81 Copper histidine (P) 0,2 g
B BLOOD AND BLOOD FORMING ORGANS 112,5103
B01 ANTITHROMBOTIC AGENTS 83,6039
B01A ANTITHROMBOTIC AGENTS 83,6039
B01AA Vitamin K antagonists 1,5288
B01AA03 Warfarin (O) 5566,1 g 0,0075 g 1,5288
B01AB Heparin group 3,4423
B01AB01 Heparin sodium (P) 591625000 U 10000 U 0,1219
B01AB05 Enoxaparin sodium (hem, P) 1151800000 U 2000 U 1,1863
B01AB05 Enoxaparin sodium (P) 1746104000 U 2000 U 1,7984
B01AB06 Nadroparin calcium (P) 2413000 U 2850 U 0,0017
5/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B01AB12 Bemiparin sodium (P) 405245000 U 2500 U 0,3339
B01AC Platelet aggregation inhibitors, excl. heparin 54,5428
B01AC04 Clopidogrel (O) 146263,8 g 0,075 g 4,0173
B01AC06 Acetylsalicylic acid (O) 4712830 pieces 1 pieces 9,7082
B01AC09 Epoprostenol (P) 0,001 g
B01AC11 Iloprost (I) 0,0437 g 0,15 mg 0,0006
B01AC11 Iloprost (P) 0,0045 g 50 mcg 0,0002
B01AC16 Eptifibatide (P) 64,365 g 0,2 g 0,0007
B01AC21 Treprostinil (P) 1,88 g 0,0043 g 0,0009
B01AC24 Ticagrelor (O) 102275,04 g 0,18 g 1,1704
B01AC27 Selexipag
(O) 3,672 g 1,8 mg 0,0042
B01AC80 Acetylsalicylic acid +Magnesium oxide (O) 19243400 pieces 1 pieces 39,6403
B01AD Enzymes 0,0023
B01AD02 Alteplase (P) 97,47 g 0,1 g 0,0020
B01AD11 Tenecteplase (P) 6,25 g 0,04 g 0,0003
B01AE Direct thrombin inhibitors 2,6545
B01AE03 Argatroban (P) 1,5 g 0,2 g <0,0001
B01AE06 Bivalirudine (P) 2,5 g 0,25 g <0,0001
B01AE07 Dabigatran etexilate (O) 386586,75 g 0,3 g 2,6545
B01AF Direct factor Xa inhibitors 21,4316
B01AF01 Rivaroxaban (O) 103850,7934 g 0,02 g 10,6963
B01AF02 Apixaban (O) 47447,55 g 10 mg 9,7739
B01AF03 Edoxaban (O) 28000,8 g 60 mg 0,9613
B01AX Other antithrombotic agents 0,0016
B01AX05 Fondaparinux sodium (P) 1,95 g 0,0025 g 0,0016
B02 ANTIHEMORRHAGICS 0,1892
B02A ANTIFIBRINOLYTICS 0,1625
B02AA Amino acids 0,1625
B02AA01 Aminocaproic acid (P) 6175 g 16 g 0,0008
B02AA02 Tranexamic acid (O) 120180 g 2 g 0,1238
B02AA02 Tranexamic acid (P) 36867,5 g 2 g 0,0380
B02B VITAMIN K AND OTHER HEMOSTATICS 0,0266
B02BA Vitamin K 0,0042
B02BA01 Phytomenadione (O) 7,5 g 0,02 g 0,0008
B02BA01 Phytomenadione (O, P) 8,03 g 0,02 g 0,0008
B02BA01 Phytomenadione (P) 25,35 g 0,02 g 0,0026
B02BB Fibrinogen 0,0001
B02BB01 Fibrinogen human (P) 345 g 5 g 0,0001
B02BC Local hemostatics
B02BC81 Fibrinogen human+Human thrombin (epil) 631 pieces
B02BD Blood coagulation factors
B02BD01 Human prothrombin complex (P) 251200 U
B02BD02 Human coagulation factor VIII (P) 3024500 U
B02BD04 Human coagulation factor IX (P) 685600 U
B02BD05 Human coagulation factor VII (P) 180000 U
B02BD06 Von Willebrand factor, human+Human coagulation factor VIII
(P) 1625250 U
B02BD08 Coagulation factor VIIa (P) 14150000 U
B02BD80 Turoctocog alfa (P) 4000 U
B02BD81 Simoctocog alfa (P) 143000 U
B02BD83 Efmoroctocog alfa (P) 3837000 U
B02BX Other systemic hemostatics 0,0223
B02BX01 Etamsylate (P) 567,5 g
B02BX04 Romiplostim (P) 0,0735 g 30 mcg 0,0050
B02BX05 Eltrombopag (O) 310,1 g 50 mg 0,0128
B02BX06 Emicizumab (P) 32,46 g 15 mg 0,0045
B03 ANTIANEMIC PREPARATIONS 28,7143
B03A IRON PREPARATIONS 4,3963
B03AA Iron bivalent, oral preparations 2,4065
B03AA07 Ferrous sulphate (O) 233643 g 0,2 g 2,4065
B03AB Iron trivalent, oral preparations
6/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B03AB80 Iron (III)-hydroxide polymaltose complex (O) 81936 g
B03AC Iron, parenteral preparations 0,1149
B03AC01 Dextriferron (P) 2053,5 g 0,1 g 0,0423
B03AC02 Iron (III)-hydroxide sucrose complex (P) 1472 g 0,1 g 0,0303
B03AC06 Iron (III)-hydroxide dextran complex (P) 1000 g 0,1 g 0,0206
B03AC80 Ferric derisomaltose (P) 1054,5 g 0,1 g 0,0217
B03AD Iron in combination with folic acid 1,8749
B03AD02 Ferrous fumarate+Folic acid (O) 509090 pieces 1 pieces 1,0487
B03AD03 Ferrous sulphate+Folic acid (O) 401100 pieces 1 pieces 0,8262
B03AE Iron in other combinations
B03AE81 Ferrous gluconate+Manganese gluconate+Copper gluconate
(O) 1653600 ml
B03AE82 Ferrous fumarate+Folic acid+Ascorbic acid (O) 35690 pieces
B03B VITAMIN B12 AND FOLIC ACID 23,3333
B03BA Vitamin B12 (cyanocobalamin and analogues) 6,5782
B03BA01 Cyanocobalamin (O) 10,3 g 1 mg 0,0212
B03BA01 Cyanocobalamin (P) 62,86 g 0,02 mg 6,4744
B03BA03 Hydroxocobalamin (P) 0,802 g 0,02 mg 0,0826
B03BB Folic acid and derivatives 16,7551
B03BB01 Folic acid (O) 3253,5 g 0,4 mg 16,7551
B03X OTHER ANTIANEMIC PREPARATIONS 0,9847
B03XA Other antianemic preparations 0,9847
B03XA02 Darbepoetin alfa (P) 1,5333 g 0,0045 mg 0,7019
B03XA03 Methoxy polyethylene glycol-epoetin beta (P) 0,3039 g 4 mcg 0,1565
B03XA80 Epoetin beta (P) 61302000 U 1000 U 0,1263
B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B05A BLOOD AND RELATED PRODUCTS
B05AA Blood substitutes and plasma protein fractions
B05AA01 Albumin (P) 913255 g
B05AA06 Gelatin agents (P) 6045000 ml
B05AA83 Gelatine+Sodium chloride+Potassium chloride+Magnesium
chloride+Sodium lactate (P) 550000 ml
B05AA86 human plasma proteins (P) 537800 ml
B05B I.V. SOLUTIONS
B05BA Solutions for parenteral nutrition
B05BA01 Amino acids (P) 1084000 ml
B05BA02 Fat emulsions (P) 107000 ml
B05BA03 Carbohydrates (P) 61720 g
B05BA03 Carbohydrates (P) 68538600 ml
B05BA10 Combinations (P) 17379915 ml
B05BB Solutions affecting the electrolyte balance
B05BB01 Electrolytes (P) 289763500 ml
B05BC Solutions producing osmotic diuresis
B05BC01 Mannitol (P) 1056000 ml
B05C IRRIGATING SOLUTIONS
B05CX Other irrigating solutions
B05CX10 Combinations (NA) 100000 ml
B05D PERITONEAL DIALYTICS
B05DA Isotonic solutions
B05DA80 Isotonic solutions (P) 10400000 ml
B05DB Hypertonic solutions
B05DB80 hypertonic solutions (P) 156132000 ml
B05DB81
Amino acids+Sodium chloride+Calcium chloride
dihydrate+Magnesium chloride hexahydrate+Sodium lactate
(P)
850000 ml
B05Z HEMODIALYTICS AND HEMOFILTRATES
B05ZB Hemofiltrates
B05ZB80
Sodium chloride+Potassium chloride+Calcium chloride
dihydrate+Magnesium chloride+Glucose+Sodium hydrogen
carbonate (P)
33840000 ml
7/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B05ZB82
Calcium chloride dihydrate+Magnesium chloride
hexahydrate+Sodium chloride+Sodium hydrogen
carbonate+Potassium chloride+Disodium phosphate dihydrate
(P)
10010000 ml
B05ZB83
Calcium chloride dihydrate+Magnesium chloride
hexahydrate+Glucose+Lactic acid+Sodium chloride+Sodium
hydrogen carbonate+Potassium chloride (P)
200000 ml
B05ZB84
Calcium chloride dihydrate+Magnesium chloride
hexahydrate+Lactic acid+Sodium hydrogen
carbonate+Sodium chloride (P)
950000 ml
B05ZB85 Sodium citrate+Sodium chloride (P) 28460000 ml
B05ZB86
Magnesium chloride hexahydrate+Sodium chloride+Potassium
chloride+Disodium phosphate dihydrate+Sodium hydrogen
carbonate (P)
12950000 ml
B05X I.V. SOLUTION ADDITIVES
B05XA Electrolyte solutions
B05XA01 Potassium chloride (P) 750 g
B05XA01 Potassium chloride (P) 3453200 ml
B05XA02 Sodium hydrogen carbonate (P) 1476500 ml
B05XA03 Sodium chloride (P) 9 g
B05XA03 Sodium chloride (P) 361069780 ml
B05XA05 Magnesium sulphate (P) 425000 ml
B05XA07 Calcium chloride (P) 418700 ml
B05XA14 Sodium glycerophosphate, hydrated (P) 133000 ml
B05XA80 Electrolytes (P) 147600 ml
B05XB Amino acids
B05XB01 Arginine (P) 4500 ml
B05XB02 Alanyl glutamine (P) 62000 ml
B05XC Vitamins
B05XC80 Vitamins (P) 8220,24 g
B05XC80 Vitamins (P) 125400 ml
B06 OTHER HEMATOLOGICAL AGENTS 0,0029
B06A OTHER HEMATOLOGICAL AGENTS 0,0029
B06AA Enzymes
B06AA03 Hyaluronidase (P) 90000 U
B06AB Heme products
B06AB81 Hemin (P) 40 ml
B06AC Drugs usedin hereditary angioedema 0,0029
B06AC01 C1-inhibitor, plasma derived (P) 315000 U 1400 U 0,0005
B06AC02 Icatibant (P) 6,15 g 0,03 g 0,0004
B06AC05 Lanadelumab (P) 20,7 g 21,4 mg 0,0020
C CARDIOVASCULAR SYSTEM 449,7935
C01 CARDIAC THERAPY 20,7126
C01A CARDIAC GLYCOSIDES 2,0111
C01AA Digitalis glycosides 2,0111
C01AA05 Digoxin (O) 242,1925 g 0,25 mg 1,9956
C01AA05 Digoxin (P) 1,85 g 0,25 mg 0,0152
C01AA06 Lanatoside C (O) 0,105 g 0,001 g 0,0002
C01B ANTIARRHYTHMICS, CLASS I AND III 4,9697
C01BA Antiarrhythmics, class Ia
C01BA13 Hydroquinidine (O) 324 g
C01BB Antiarrhythmics, class Ib 0,0192
C01BB02 Mexiletine (O) 160 g 0,8 g 0,0004
C01BB80 Aethacizin (O) 1822,5 g 0,2 g 0,0188
C01BC Antiarrhythmics, class Ic 3,3101
C01BC03 Propafenone (O) 458685 g 0,3 g 3,1496
C01BC03 Propafenone (P) 359,1 g 0,3 g 0,0025
C01BC04 Flecainide (O) 15326 g 0,2 g 0,1579
C01BC04 Flecainide (P) 18,75 g 0,2 g 0,0002
C01BD Antiarrhythmics, class III 1,6405
C01BD01 Amiodarone (O) 152766 g 0,2 g 1,5734
C01BD01 Amiodarone (P) 5427 g 0,2 g 0,0559
8/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C01BD07 Dronedarone (O) 4320 g 0,8 g 0,0111
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES 0,6722
C01CA Adrenergic and dopaminergic agents 0,6705
C01CA01 Etilefrine (O) 2,0625 g 0,05 g 0,0001
C01CA02 Isoprenaline (P) 0,657 g 0,09 g <0,0001
C01CA03 Norepinephrine (P) 396,04 g 0,006 g 0,1360
C01CA04 Dopamine (P) 622 g 0,5 g 0,0026
C01CA06 Phenylephrine (P) 118 g 0,004 g 0,0608
C01CA07 Dobutamine (P) 837,5 g 0,5 g 0,0035
C01CA17 Midodrine (O) 10,95 g 0,03 g 0,0008
C01CA24 Epinephrine (intraoss, P) 44,56 g 0,5 mg 0,1836
C01CA24 Epinephrine (P) 57,694 g 0,5 mg 0,2377
C01CA26 Ephedrine (P) 1108,25 g 0,05 g 0,0457
C01CE Phosphodiesterase inhibitors 0,0012
C01CE02 Milrinone (P) 28,06 g 0,05 g 0,0012
C01CX Other cardiac stimulants 0,0005
C01CX08 Levosimendan (P) 2,9 g 11 mg 0,0005
C01CX80 Ammonia (I) 1450280 ml
C01D VASODILATORS USED IN CARDIAC DISEASES 5,3544
C01DA Organic nitrates 5,3527
C01DA02 Glyceryl trinitrate (P) 172,1 g
C01DA02 Glyceryl trinitrate (SL) 496,752 g 0,0025 g 0,4093
C01DA05 Pentaerithrityl tetranitrate (O) 3 g 0,12 g 0,0001
C01DA08 Isosorbide dinitrate (O) 22,5 g 0,06 g 0,0008
C01DA08 Isosorbide dinitrate (SL) 261,975 g 0,02 g 0,0270
C01DA14 Isosorbide mononitrate (O) 95450,2 g 0,04 g 4,9156
C01DX Other vasodilatators used in cardiac diseases 0,0018
C01DX80 Meldonium (O) 615 g 0,75 g 0,0017
C01DX80 Meldonium (P) 25 g 0,75 g 0,0001
C01E OTHER CARDIAC PREPARATIONS 7,7052
C01EA Prostaglandins 0,0002
C01EA01 Alprostadil (P) 0,0448 g 0,5 mg 0,0002
C01EB Other cardiac preparations 7,7050
C01EB10 Adenosine (P) 119,192 g 0,015 g 0,0164
C01EB15 Trimetazidine (O) 140036,4 g 0,04 g 7,2117
C01EB16 Ibuprofen (P) 0,4 g 0,03 g <0,0001
C01EB17 Ivabradine (O) 1847,58 g 0,01 g 0,3806
C01EB18 Ranolazine (O) 69427,5 g 1,5 g 0,0953
C01EB21 Regadenoson (P) 0,188 g 0,4 mg 0,0010
C01EB80 Hawthorn berry (O) 31040 ml
C02 ANTIHYPERTENSIVES 3,7403
C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING 2,3417
C02AC Imidazoline receptor agonists 2,3417
C02AC01 Clonidine (O) 5,025 g 0,45 mg 0,0230
C02AC01 Clonidine (P) 2,829 g 0,45 mg 0,0130
C02AC02 Guanfacine (O) 0,196 g 3 mg 0,0001
C02AC05 Moxonidine (O) 335,783 g 0,3 mg 2,3056
C02C ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING 1,3603
C02CA Alpha-adrenoreceptor antagonists 1,3603
C02CA01 Prazosin (O) 1,62 g 0,005 g 0,0007
C02CA04 Doxazosin (O) 2640,116 g 0,004 g 1,3596
C02D ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON 0,0006
C02DD Nitroferricyanide derivatives 0,0006
C02DD01 Sodium nitroprusside (P) 14,25 g 0,05 g 0,0006
C02K OTHER ANTIHYPERTENSIVES 0,0377
C02KX Antihypertensives for pulmonary arterial hypertension 0,0377
C02KX01 Bosentan (O) 1368,5 g 0,25 g 0,0113
C02KX02 Ambrisentan (O) 49,95 g 7,5 mg 0,0137
C02KX04 Macitentan (O) 4,8 g 10 mg 0,0010
C02KX05 Riociguat (O) 25,494 g 4,5 mg 0,0117
C03 DIURETICS 26,3879
C03A LOW-CEILING DIURETICS, THIAZIDES 1,2035
9/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C03AA Thiazides, plain 1,2035
C03AA03 Hydrochlorothiazide (O) 14605,5 g 0,025 g 1,2035
C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES 2,1909
C03BA Sulfonamides, plain 2,1909
C03BA11 Indapamide (O) 2658,9 g 2,5 mg 2,1909
C03C HIGH-CEILING DIURETICS 19,5433
C03CA Sulfonamides, plain 19,5433
C03CA01 Furosemide (O) 62122,6 g 0,04 g 3,1992
C03CA01 Furosemide (P) 4993 g 0,04 g 0,2571
C03CA04 Torasemide (O) 116733 g 0,015 g 16,0309
C03CA04 Torasemide (P) 407,8 g 0,015 g 0,0560
C03D ALDOSTERONE ANTAGONISTS AND OTHER POTASSIUM-
SPARING AGENTS 3,4324
C03DA Aldosterone antagonists 3,4324
C03DA01 Spironolactone (O) 124934,25 g 0,075 g 3,4314
C03DA04 Eplerenone (O) 23,25 g 0,05 g 0,0010
C03E DIURETICS AND POTASSIUM-SPARING AGENTS IN
COMBINATION 0,0179
C03EA Low-ceiling diuretics and potassium-sparing agents 0,0179
C03EA81 Hydrochlorothiazide+Amiloride (O) 8700 pieces 1 pieces 0,0179
C04 PERIPHERAL VASODILATORS 2,5427
C04A PERIPHERAL VASODILATORS 2,5427
C04AC Nicotinic acid and derivatives 0,0004
C04AC01 Nicotinic acid (P) 38 g 0,2 g 0,0004
C04AD Purine derivatives 1,4605
C04AD02 Xantinol nicotinate (O) 54 g 0,9 g 0,0001
C04AD03 Pentoxifylline (O) 707552 g 1 g 1,4575
C04AD03 Pentoxifylline (P) 418 g 0,3 g 0,0029
C04AX Other peripheral vasodilators 1,0818
C04AX21 Naftidrofuryl (O) 315090 g 0,6 g 1,0818
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL
FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA82 Hydrocortisone+Cinchocaine (R) 13788 pieces
C05AA84 Fluocortolone+Lidocaine (R) 215700 g
C05AA84 Fluocortolone+Lidocaine (R) 272520 pieces
C05AX Other agents for treatment of hemorrhoids and anal fissures
for topical use
C05AX81 Xeroformium+Zinc sulphate+Extract of Belladonna (R) 2880 pieces
C05AX83 Yeast cell extract+Shark liver oil (R) 265440 pieces
C05B ANTIVARICOSE THERAPY
C05BA Heparins or heparinoids for topical use
C05BA03 Heparin sodium (C) 7546000 g
C05BB Sclerosing agents for local injection
C05BB02 Lauromacrogol 400 (P) 81,375 g
C05C CAPILLARY STABILIZING AGENTS
C05CA Bioflavonoids
C05CA01 Rutoside (O) 216750 pieces
C05CA03 Diosmin (O) 510690 g
C05CA04 Troxerutin (C) 3559740 g
C05CA04 Troxerutin (O) 202395 g
C05CA53 Diosmin+Hesperidine (O) 2220 pieces
C05CA53 Diosmin+Hesperidine (O) 42619,5 g
C07 BETA BLOCKING AGENTS 57,0059
C07A BETA BLOCKING AGENTS 57,0054
C07AA Beta blocking agents, non-selective 1,5725
C07AA05 Propranolol (O) 50817,5 g 0,16 g 0,6543
C07AA07 Sotalol (O) 71325,6 g 0,16 g 0,9183
C07AB Beta blocking agents, selective 54,8343
C07AB02 Metoprolol (O) 1975176,05 g 0,15 g 27,1250
C07AB02 Metoprolol (P) 111,725 g 0,15 g 0,0015
10/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C07AB03 Atenolol (O) 16983,75 g 0,075 g 0,4665
C07AB07 Bisoprolol (O) 18936,45 g 0,01 g 3,9008
C07AB12 Nebivolol (O) 56653,14 g 0,005 g 23,3405
C07AG Alpha and beta blocking agents 0,5985
C07AG01 Labetalol (O) 31350 g 0,6 g 0,1076
C07AG01 Labetalol (P) 1484 g 0,6 g 0,0051
C07AG02 Carvedilol (O) 8843,8125 g 0,0375 g 0,4858
C07B BETA BLOCKING AGENTS AND THIAZIDES 0,0005
C07BB Beta blocking agents, selective, and thiazides 0,0005
C07BB07 Bisoprolol+Hydrochlorothiazide (O) 240 pieces 1 pieces 0,0005
C08 CALCIUM CHANNEL BLOCKERS 44,0099
C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH
MAINLY VASCULAR EFFECTS 42,6730
C08CA Dihydropyridine derivatives 42,6730
C08CA01 Amlodipine (O) 62464,8 g 0,005 g 25,7348
C08CA02 Felodipine (O) 5197,275 g 0,005 g 2,1412
C08CA05 Nifedipine (O) 13717,76 g 0,03 g 0,9419
C08CA06 Nimodipine (O) 351 g 0,3 g 0,0024
C08CA06 Nimodipine (P) 3,42 g 0,05 g 0,0001
C08CA08 Nitrendipine (O) 38023,12 g 0,02 g 3,9163
C08CA09 Lacidipine (O) 5458,544 g 0,004 g 2,8111
C08CA13 Lercanidipine (O) 34588,8 g 0,01 g 7,1251
C08D SELECTIVE CALCIUM CHANNEL BLOCKERS WITH
DIRECT CARDIAC EFFECTS 1,3369
C08DA Phenylalkylamine derivatives 1,2170
C08DA01 Verapamil (O) 141780 g 0,24 g 1,2169
C08DA01 Verapamil (P) 10,525 g 0,24 g 0,0001
C08DB Benzothiazepine derivatives 0,1199
C08DB01 Diltiazem (O) 13971,6 g 0,24 g 0,1199
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM 207,0866
C09A ACE INHIBITORS, PLAIN 72,7975
C09AA ACE inhibitors, plain 72,7975
C09AA01 Captopril (O) 359 g 0,05 g 0,0148
C09AA02 Enalapril (O) 34805,66 g 0,01 g 7,1698
C09AA02 Enalapril (P) 10,1875 g 0,01 g 0,0021
C09AA04 Perindopril (O) 16900,14 g 0,004 g 8,7033
C09AA05 Ramipril (O) 64093,595 g 2,5 mg 52,8117
C09AA09 Fosinopril (O) 29211,56 g 0,015 g 4,0116
C09AA10 Trandolapril (O) 81,704 g 0,002 g 0,0842
C09B ACE INHIBITORS, COMBINATIONS 57,2270
C09BA ACE inhibitors and diuretics 28,6124
C09BA02 Enalapril+Hydrochlorothiazide (O) 2418812 pieces 1 pieces 4,9826
C09BA04 Perindopril+Indapamide (O) 9832740 pieces 1 pieces 20,2549
C09BA05 Ramipril+Hydrochlorothiazide (O) 1121282 pieces 1 pieces 2,3098
C09BA06 Quinapril+Hydrochlorothiazide (O) 150 pieces 1 pieces 0,0003
C09BA09 Fosinopril+Hydrochlorothiazide (O) 516888 pieces 1 pieces 1,0648
C09BB ACE inhibitors and calcium channel blockers 12,7735
C09BB03 Lisinopril+Amlodipine (O) 734790 pieces 1 pieces 1,5136
C09BB04 Perindopril+Amlodipine (O) 4482630 pieces 1 pieces 9,2340
C09BB07 Ramipril+Amlodipine (O) 746490 pieces 1 pieces 1,5377
C09BB10 Trandolapril+Verapamil (O) 236992 pieces 1 pieces 0,4882
C09BX ACE inhibitors, other combinations 15,8411
C09BX01 Perindopril+Amlodipine+Indapamide (O) 7690080 pieces 1 pieces 15,8411
C09C ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS), PLAIN 43,1342
C09CA Angiotensin II receptor blockers (ARBs), plain 43,1342
C09CA01 Losartan (O) 79278,3 g 0,05 g 3,2662
C09CA02 Eprosartan (O) 823,2 g 0,6 g 0,0028
C09CA03 Valsartan (O) 160637,12 g 0,08 g 4,1363
C09CA06 Candesartan (O) 42075,84 g 0,008 g 10,8342
C09CA07 Telmisartan (O) 419850,96 g 0,04 g 21,6217
C09CA08 Olmesartan medoxomil (O) 31776,92 g 0,02 g 3,2729
11/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C09D ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS),
COMBINATIONS 33,9279
C09DA Angiotensin II receptor blockers (ARBs) and diuretics 14,6674
C09DA01 Losartan+Hydrochlorothiazide (O) 815330 pieces 1 pieces 1,6795
C09DA03 Valsartan+Hydrochlorothiazide (O) 831712 pieces 1 pieces 1,7133
C09DA06 Candesartan+Hydrochlorothiazide (O) 1099280 pieces 1 pieces 2,2645
C09DA07 Telmisartan+Hydrochlorothiazide (O) 4109742 pieces 1 pieces 8,4658
C09DA08 Olmesartan medoxomil+Hydrochlorothiazide (O) 264240 pieces 1 pieces 0,5443
C09DB Angiotensin II receptor blockers (ARBs) and calcium channel
blockers 13,5183
C09DB01 Valsartan+Amlodipine (O) 230026 pieces 1 pieces 0,4738
C09DB02 Olmesartan medoxomil+Amlodipine (O) 3086804 pieces 1 pieces 6,3586
C09DB04 Telmisartan+Amlodipine (O) 3179484 pieces 1 pieces 6,5496
C09DB07 Candesartan+Amlodipine (O) 66164 pieces 1 pieces 0,1363
C09DX Angiotensin II receptor blockers (ARBs), other combinations 5,7422
C09DX01 Valsartan+Amlodipine+Hydrochlorothiazide (O) 3696 pieces 1 pieces 0,0076
C09DX03 Olmesartan medoxomil+Amlodipine+Hydrochlorothiazide (O) 2415476 pieces 1 pieces 4,9757
C09DX04 Valsartan+Sacubitril (O) 368368 pieces 1 pieces 0,7588
C10 LIPID MODIFYING AGENTS 88,3076
C10A LIPID MODIFYING AGENTS, PLAIN 84,9056
C10AA HMG CoA reductase inhibitors 83,6112
C10AA01 Simvastatin (O) 60920,2 g 0,03 g 4,1831
C10AA03 Pravastatin (O) 3834,6 g 0,03 g 0,2633
C10AA04 Fluvastatin (O) 14976,64 g 0,06 g 0,5142
C10AA05 Atorvastatin (O) 330680,4 g 0,02 g 34,0592
C10AA07 Rosuvastatin (O) 216469,24 g 0,01 g 44,5915
C10AB Fibrates 0,6805
C10AB05 Fenofibrate (O) 66072 g 0,2 g 0,6805
C10AC Bile acid sequestrants 0,0015
C10AC01 Colestyramine (O) 9800 g 14 g 0,0014
C10AC02 Colestipol (O) 250 g 20 g <0,0001
C10AX Other lipid modifying agents 0,6125
C10AX09 Ezetimibe (O) 2834,8 g 0,01 g 0,5840
C10AX13 Evolocumab (P) 86,52 g 10 mg 0,0178
C10AX14 Alirocumab (P) 28,05 g 5,4 mg 0,0107
C10AX80 Omega-3-acid ethyl esters 90 (O) 40740 g
C10AX80 Omega-3-acid ethyl esters 90 (O) 168336 pieces
C10B LIPID MODIFYING AGENTS, COMBINATIONS 3,4020
C10BA Combinations of various lipid modifying agents 2,7743
C10BA05 Atorvastatin+Ezetimibe (O) 142860 pieces 1 pieces 0,2943
C10BA06 Rosuvastatin+Ezetimibe (O) 1203900 pieces 1 pieces 2,4800
C10BX Lipid modifying agents in combination with other drugs 0,6277
C10BX11 Atorvastatin+Amlodipine+Perindopril (O) 204180 pieces 1 pieces 0,4206
C10BX13 Rosuvastatin+Perindopril+Indapamide (O) 83820 pieces 1 pieces 0,1727
C10BX15 Atorvastatin+Perindopril (O) 16740 pieces 1 pieces 0,0345
D DERMATOLOGICALS 1,8152
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE 0,9776
D01A ANTIFUNGALS FOR TOPICAL USE
D01AC Imidazole and triazole derivatives
D01AC01 Clotrimazole (C) 502455,4 g
D01AC05 Isoconazole (C) 253810 g
D01AC08 Ketoconazole (C) 80500 ml
D01AC08 Ketoconazole (C) 1123900,2 g
D01AC80 Isoconazole+Diflucortolone (C) 923940 g
D01AC81 Clotrimazole+Hexamidine (C) 120360 g
D01AE Other antifungals for topical use
D01AE14 Ciclopirox (C) 48,312 g
D01AE15 Terbinafine (C) 520571 g
D01AE16 Amorolfine (C) 27837,5 ml
D01AE22 Naftifine (C) 158750 ml
D01AE22 Naftifine (C) 204045 g
D01B ANTIFUNGALS FOR SYSTEMIC USE 0,9776
12/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D01BA Antifungals for systemic use 0,9776
D01BA01 Griseofulvin (O) 612,5 g 0,5 g 0,0025
D01BA02 Terbinafine (O) 118336,5 g 0,25 g 0,9751
D02 EMOLLIENTS AND PROTECTIVES
D02A EMOLLIENTS AND PROTECTIVES
D02AB Zinc products
D02AB80 Zinc oxide (C) 337980 g
D02AE Carbamide products
D02AE01 Urea (C) 42550 g
D02B PROTECTIVES AGAINST UV-RADIATION
D02BA Protectives against UV-radiation for topical use
D02BA01 4-Aminobenzoic acid (O) 720 g
D03 PREPARATIONS FOR TREATMENT OF WOUNDS AND
ULCERS
D03A CICATRIZANTS
D03AX Other cicatrizants
D03AX03 Dexpanthenol (C) 3965440 g
D03AX81 Heparin sodium+Allantoin+Extract of Cepae (C) 121020 g
D03AX83 Dexpanthenol+Chlorhexidine (C) 2171040 g
D03B ENZYMES
D03BA Proteolytic enzymes
D03BA80 Collagenase+Chloramphenicol (C) 90 g
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS,
ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS,
ETC.
D04AA Antihistamines for topical use
D04AA09 Chloropyramine (P) 1 g
D05 ANTIPSORIATICS 0,0510
D05A ANTIPSORIATICS FOR TOPICAL USE
D05AA Tars
D05AA85 Coal tar+Salicylic acid (C) 675400 ml
D05AX Other antipsoriatics for topical use
D05AX80 Calcipotriol+Betamethasone (C) 969120 g
D05B ANTIPSORIATICS FOR SYSTEMIC USE 0,0510
D05BB Retinoids for treatment of psoriasis 0,0510
D05BB02 Acitretin (O) 866,4 g 0,035 g 0,0510
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR
DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE
D06AX Other antibiotics for topical use
D06AX01 Fusidic acid (C) 199785 g
D06AX02 Chloramphenicol (C) 500 g
D06AX09 Mupirocin (C) 1125 g
D06AX80 Bacitracin+Neomycin (C) 50550 g
D06AX84 Chloramphenicol+Methyluracil (C) 4800 g
D06B CHEMOTHERAPEUTICS FOR TOPICAL USE
D06BA Sulfonamides
D06BA01 Silver sulfadiazine (C) 1596065 g
D06BB Antivirals
D06BB03 Aciclovir (C) 198966 g
D06BB04 Podophyllotoxin (C) 1564,5 ml
D06BB10 Imiquimod (C) 5442 g
D06BB81 Aciclovir+Hydrocortisone (C) 27100 g
D06BX Other chemotherapeutics
D06BX01 Metronidazole (C) 85026,975 g
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AA Corticosteroids, weak (group I)
D07AA02 Hydrocortisone (C) 609050 g
13/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D07AB Corticosteroids, moderately potent (group II)
D07AB09 Triamcinolone (C) 260,0045 g
D07AC Corticosteroids, potent (group III)
D07AC01 Betamethasone (C) 140415 g
D07AC04 Fluocinolone acetonide (C) 345 g
D07AC13 Mometasone (C) 341080 ml
D07AC13 Mometasone (C) 1177992,465 g
D07AC14 Methylprednisolone aceponate (C) 617415 g
D07AC17 Fluticasone (C) 46080 g
D07AD Corticosteroids, very potent (group IV)
D07AD01 Clobetasol (C) 82025 ml
D07AD01 Clobetasol (C) 938206,9625 g
D07B CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS
D07BA Corticosteroids, weak, combinations with antiseptics
D07BA80 Hydrocortisone+Chlorhexidine (C) 337140 g
D07BC Corticosteroids, potent, combinations with antiseptics
D07BC80 Betamethasone+Salicylic acid (C) 21030 g
D07BC80 Betamethasone+Salicylic acid (C) 945250 ml
D07C CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
D07CA Corticosteroids, weak, combinations with antibiotics
D07CA83 Hydrocortisone+Fusidic acid (C) 78090 g
D07CC Corticosteroids, potent, combinations with antibiotics
D07CC80 Betamethasone+Fusidic acid (C) 601440 g
D07CC83 Betamethasone+Gentamicin (C) 120 g
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XA Corticosteroids, weak, other combinations
D07XA81 Prednisolone+Salicylic acid (C) 232700 ml
D07XC Corticosteroids, potent, other combinations
D07XC03 Mometasone+Salicylic acid (C) 400 g
D08 ANTISEPTICS AND DISINFECTANTS
D08A ANTISEPTICS AND DISINFECTANTS
D08AG Iodine products
D08AG02 Povidone, iodinated (C) 1134220 ml
D08AG02 Povidone, iodinated (C) 3790020 g
D08AG03 Iodine (C) 893960 ml
D08AJ Quaternary ammonium compounds
D08AJ81 Octenidine+Phenoxyethanol (C) 11159000 ml
D08AX Other antiseptics and disinfectants
D08AX82 Tar+Castor oil+Xeroformium (C) 6150 g
D08AX83 Brilliant Green (C) 241620 ml
D10 ANTI-ACNE PREPARATIONS 0,6570
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AD Retinoids for topical use in acne
D10AD01 Tretinoin (C) 41970 g
D10AD03 Adapalene (C) 51480 g
D10AD80 Adapalene+Benzoyl peroxide (C) 114300 g
D10AD81 Tretinoin+Erythromycin (C) 24030 g
D10AF Antiinfectives for treatment of acne
D10AF01 Clindamycin (C) 2250 ml
D10AF02 Erythromycin (C) 348600 ml
D10AF81 Clindamycin+Benzoyl peroxide (C) 297975 g
D10AF82 Clindamycin+Tretinoin (C) 147360 g
D10AX Other anti-acne preparations for topical use
D10AX03 Azelaic acid (C) 314574 g
D10B ANTI-ACNE PREPARATIONS FOR SYSTEMIC USE 0,6570
D10BA Retinoids for treatment of acne 0,6570
D10BA01 Isotretinoin (O) 9567,6 g 0,03 g 0,6570
D11 OTHER DERMATOLOGICAL PREPARATIONS 0,1296
D11A OTHER DERMATOLOGICAL PREPARATIONS 0,1296
D11AF Wart and anti-corn preparations
D11AF80 Salicylic acid+Lactic acid (C) 78075 ml
14/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D11AH Agents for dermatitis, excluding corticosteroids 0,0484
D11AH01 Tacrolimus (C) 108540 g
D11AH02 Pimecrolimus (C) 226350 g
D11AH05 Dupilumab (P) 502,4 g 21,4 mg 0,0484
D11AX Other dermatologicals 0,0813
D11AX01 Minoxidil (C) 207300 ml
D11AX10 Finasteride (O) 39,452 g 0,001 g 0,0813
D11AX16 Eflornithine (C) 480 g
D11AX21 Brimonidine (C) 90 g
D11AX22 Ivermectin (C) 67860 g
D11AX82 Hydroquinone+Fluocinolone acetonide+Tretinoin (C) 30 g
G GENITO URINARY SYSTEM AND SEX HORMONES 56,4804
G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS 0,7699
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL.
COMBINATIONS WITH CORTICOSTEROIDS 0,7699
G01AA Antibiotics 0,0420
G01AA01 Nystatin (O) 1200000 U
G01AA10 Clindamycin (V) 2041,1 g 0,1 g 0,0420
G01AC Quinoline derivatives 0,0434
G01AC05 Dequalinium (V) 421,14 g 20 mg 0,0434
G01AF Imidazole derivatives 0,6845
G01AF01 Metronidazole (V) 9998 g 0,5 g 0,0412
G01AF02 Clotrimazole (V) 26696 g 0,1 g 0,5499
G01AF05 Econazole (V) 4533,3 g 0,1 g 0,0934
G02 OTHER GYNECOLOGICALS 4,0514
G02A UTEROTONICS 0,1418
G02AB Ergot alkaloids 0,0022
G02AB01 Methylergometrine (P) 0,2168 g 0,2 mg 0,0022
G02AD Prostaglandins 0,1395
G02AD02 Dinoprostone (P) 0,42 g
G02AD02 Dinoprostone (V) 1,8739 g 0,5 mg 0,0077
G02AD06 Misoprostol (O) 12,799 g 0,2 mg 0,1318
G02B CONTRACEPTIVES FOR TOPICAL USE 2,3182
G02BA Intrauterine contraceptives 0,0177
G02BA03 Levonorgestrel (V) 8595 pieces 1 pieces 0,0177
G02BB Intravaginal contraceptives 2,3005
G02BB01 Etonogestrel+Ethinylestradiol (V) 39021 pieces 0,036 pieces 2,2328
G02BB81 Benzalkonium chloride (V) 32880 pieces 1 pieces 0,0677
G02BB81 Benzalkonium chloride (V) 37656 g
G02C OTHER GYNECOLOGICALS 1,5914
G02CA Sympathomimetics, labour repressants
G02CA80 Hexoprenaline (P) 0,0103 g
G02CB Prolactine inhibitors 0,1391
G02CB01 Bromocriptine (O) 271,425 g 0,005 g 0,1118
G02CB03 Cabergoline (O) 6,62 g 0,5 mg 0,0273
G02CX Other gynecologicals 1,4523
G02CX01 Atosiban (P) 1,0388 g 0,165 g <0,0001
G02CX03 Agni casti fructus (O) 386280 pieces 1 pieces 0,7957
G02CX04 Cimicifugae rhizoma (O) 637440 pieces 2 pieces 0,6565
G03 SEX HORMONES AND MODULATORS OF THE GENITAL
SYSTEM 30,3378
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE 23,3445
G03AA Progestogens and estrogens, fixed combinations 18,3957
G03AA07 Levonorgestrel+Ethinylestradiol (O) 220724 pieces 1 pieces 0,4547
G03AA09 Desogestrel+Ethinylestradiol (O) 360612 pieces 0,75 pieces 0,9905
G03AA10 Gestodene+Ethinylestradiol (O) 2008944 pieces 0,75 pieces 5,5178
G03AA12 Drospirenone+Ethinylestradiol (O) 1102500 pieces 1 pieces 2,2711
G03AA12 Drospirenone+Ethinylestradiol (O) 1553874 pieces 0,75 pieces 4,2679
G03AA13 Norelgestromin+Ethinylestradiol (TD) 89901 pieces 0,107 pieces 1,7308
G03AA14 Nomegestrol+Estradiol (O) 1512 pieces 1 pieces 0,0031
G03AA15 Chlormadinone+Ethinylestradiol (O) 137592 pieces 0,75 pieces 0,3779
G03AA16 Dienogest+Ethinylestradiol (O) 1012907 pieces 0,75 pieces 2,7820
15/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G03AB Progestogens and estrogens, sequential preparations 0,1666
G03AB05 Desogestrel+Ethinylestradiol (O) 1650 pieces 0,75 pieces 0,0045
G03AB08 Dienogest+Estradiol valerate (O) 78680 pieces 1 pieces 0,1621
G03AC Progestogens 4,7022
G03AC08 Etonogestrel (P) 63,512 g 68 mcg 1,9240
G03AC09 Desogestrel (O) 1326724 pieces 1 pieces 2,7330
G03AC10 Drospirenone (O) 21952 pieces 1 pieces 0,0452
G03AD Emergency contraceptives 0,0800
G03AD01 Levonorgestrel (O) 56,8935 g 1,5 mg 0,0781
G03AD02 Ulipristal (O) 27,27 g 0,03 g 0,0019
G03B ANDROGENS 0,2711
G03BA 3-oxoandrosten (4) derivatives 0,2711
G03BA03 Testosterone (O) 14,4 g 0,12 g 0,0002
G03BA03 Testosterone (P) 2357,75 g 0,018 g 0,2698
G03BA03 Testosterone (TD) 25,76 g 0,05 g 0,0011
G03C ESTROGENS 1,5141
G03CA Natural and semisynthetic estrogens, plain 1,5000
G03CA03 Estradiol (C, V) 60875 g
G03CA03 Estradiol (O) 834,232 g 2 mg 0,8592
G03CA03 Estradiol (TD) 53,1216 g 1,53 mg 0,0715
G03CA03 Estradiol (TD) 77,7 g 1 mg 0,1601
G03CA03 Estradiol (V) 2,8688 g 0,025 mg 0,2364
G03CA04 Estriol (V) 16,7775 g 0,2 mg 0,1728
G03CA80 Estradiol+Prednisolone (C) 61150 g
G03CX Other estrogens 0,0141
G03CX01 Tibolone (O) 17,15 g 2,5 mg 0,0141
G03D PROGESTOGENS 2,2967
G03DA Pregnen (4) derivatives 1,5341
G03DA02 Medroxyprogesterone (O) 74,55 g 0,005 g 0,0307
G03DA02 Medroxyprogesterone (P) 291,465 g 0,007 g 0,0858
G03DA04 Progesterone (O) 9426 g 0,3 g 0,0647
G03DA04 Progesterone (P) 314,9915 g 0,005 g 0,1298
G03DA04 Progesterone (V) 53438,1 g 0,09 g 1,2231
G03DB Pregnadien derivatives 0,7619
G03DB01 Dydrogesterone (O) 2673,4 g 0,01 g 0,5507
G03DB08 Dienogest (O) 205,016 g 2 mg 0,2112
G03DC Estren derivatives 0,0007
G03DC02 Norethisterone (O) 1,8 g 0,005 g 0,0007
G03F PROGESTOGENS AND ESTROGENS IN COMBINATION 2,0851
G03FA Progestogens and estrogens, fixed combinations 1,6641
G03FA01 Norethisterone+Estradiol (O) 493276 pieces 1 pieces 1,0161
G03FA14 Dydrogesterone+Estradiol (O) 139468 pieces 1 pieces 0,2873
G03FA17 Drospirenone+Estradiol (O) 175112 pieces 1 pieces 0,3607
G03FB Progestogens and estrogens, sequential preparations 0,4210
G03FB05 Norethisterone+Estradiol (O) 147168 pieces 1 pieces 0,3032
G03FB08 Dydrogesterone+Estradiol (O) 57204 pieces 1 pieces 0,1178
G03G GONADOTROPINS AND OTHER OVULATION STIMULANTS 0,4704
G03GA Gonadotropins 0,1804
G03GA05 Follitropin alfa (P) 5525175 U 75 U 0,1518
G03GA07 Lutropin alfa (P) 679650 U 75 U 0,0187
G03GA08 Choriogonadotropin alfa (P) 0,859 g 0,25 mg 0,0071
G03GA30 Follitropin alfa+Lutropin alfa (P) 1427 doses 1 doses 0,0029
G03GB Ovulation stimulants, synthetic 0,2899
G03GB02 Clomifene (O) 1266,7 g 0,009 g 0,2899
G03H ANTIANDROGENS 0,3519
G03HA Antiandrogens, plain 0,0739
G03HA01 Cyproterone (O) 3587,5 g 0,1 g 0,0739
G03HB Antiandrogens and estrogens 0,2780
G03HB01 Cyproterone+Estrogen (O) 101220 pieces 0,75 pieces 0,2780
G03X OTHER SEX HORMONES AND MODULATORS OF THE
GENITAL SYSTEM 0,0040
16/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G03XB Progesterone receptor modulators 0,0038
G03XB01 Mifepristone (O) 840 g 0,6 g 0,0029
G03XB02 Ulipristal (O) 2,24 g 5 mg 0,0009
G03XC Selective estrogen receptor modulators 0,0002
G03XC01 Raloxifene (O) 5,04 g 0,06 g 0,0002
G04 UROLOGICALS 21,3212
G04B UROLOGICALS 3,8300
G04BD Drugs for urinary frequency and incontinence 2,2222
G04BD04 Oxybutynin (O) 4560,6 g 0,015 g 0,6263
G04BD06 Propiverine (O) 14,7 g 0,03 g 0,0010
G04BD07 Tolterodine (O) 640,416 g 0,004 g 0,3298
G04BD08 Solifenacin (O) 945,45 g 0,005 g 0,3895
G04BD09 Trospium chloride (O) 3707,55 g 0,04 g 0,1909
G04BD12 Mirabegron (O) 16617 g 50 mg 0,6846
G04BE Drugs used in erectile dysfunction 1,5962
G04BE01 Alprostadil (P) 0,0461 g 0,02 mg 0,0047
G04BE03 Sildenafil (O) 26924,2 g 0,05 g 1,1092
G04BE08 Tadalafil (O) 2035,76 g 0,01 g 0,4194
G04BE09 Vardenafil (O) 55,12 g 0,01 g 0,0114
G04BE10 Avanafil (O) 2498,8 g 0,1 g 0,0515
G04BX Other urologicals 0,0116
G04BX14 Dapoxetin (O) 169,29 g 0,03 g 0,0116
G04BX80 Centaury+Lovage root+Rosemary leaf (O) 1137060 pieces
G04BX90 Extr. prostatae (P) 1000 pieces
G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY 17,4913
G04CA Alpha-adrenoreceptor antagonists 14,4261
G04CA01 Alfuzosin (O) 8334,6 g 7,5 mg 2,2892
G04CA02 Tamsulosin (O) 1603,536 g 0,4 mg 8,2580
G04CA04 Silodosin (O) 789,36 g 8 mg 0,2033
G04CA52 Tamsulosin+Dutasteride (O) 1784340 pieces 1 pieces 3,6756
G04CB Testosterone-5-alpha reductase inhibitors 0,5665
G04CB01 Finasteride (O) 451,67 g 0,005 g 0,1861
G04CB02 Dutasteride (O) 92,325 g 0,5 mg 0,3804
G04CX Other drugs used in benign prostatic hypertrophy 2,4988
G04CX02 Sabalis serrulatae fructus (O) 388166,4 g 0,32 g 2,4988
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX
HORMONES AND INSULINS 31,2564
H01 PITUITARY AND HYPOTHALAMIC HORMONES AND
ANALOGUES 0,4655
H01A ANTERIOR PITUITARY LOBE HORMONES AND
ANALOGUES 0,1784
H01AA ACTH 0,0002
H01AA02 Tetracosactide (P) 0,02 g 0,25 mg 0,0002
H01AB Thyrotropin 0,0003
H01AB01 Thyrotropin alfa (P) 0,1368 g 0,9 mg 0,0003
H01AC Somatropin and somatropin agonists 0,1604
H01AC01 Somatropin (P) 155737,6372 U 2 U 0,1604
H01AX Other anterior pituitary lobe hormones and analogues 0,0175
H01AX01 Pegvisomant (P) 84,9 g 0,01 g 0,0175
H01B POSTERIOR PITUITARY LOBE HORMONES 0,1513
H01BA Vasopressin and analogues 0,1037
H01BA01 Argipressin (P) 44400 U 40 U 0,0023
H01BA02 Desmopressin (N) 0,015 g 0,025 mg 0,0012
H01BA02 Desmopressin (P) 0,0201 g 0,004 mg 0,0104
H01BA02 Desmopressin (SL) 10,4688 g 0,24 mg 0,0899
H01BB Oxytocin and analogues 0,0476
H01BB01 Demoxytocin (O) 850000 U 100 U 0,0175
H01BB02 Oxytocin (P) 195900 U 15 U 0,0269
H01BB03 Carbetocin (P) 0,1556 g 0,1 mg 0,0032
H01C HYPOTHALAMIC HORMONES 0,1358
H01CA Gonadotropin-releasing hormones
H01CA01 Gonadorelin (P) 0,0037 g
17/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
H01CB Somatostatin and analogues 0,1137
H01CB02 Octreotide (P) 9,043 g 0,7 mg 0,0266
H01CB03 Lanreotide (P) 112,05 g 3 mg 0,0769
H01CB05 Pasireotide (P) 5,94 g 1,2 mg 0,0102
H01CC Anti-gonadotropin-releasing hormones 0,0220
H01CC02 Cetrorelix (P) 2,6718 g 0,25 mg 0,0220
H02 CORTICOSTEROIDS FOR SYSTEMIC USE 9,8660
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN 9,8617
H02AA Mineralocorticoids 0,1765
H02AA02 Fludrocortisone (O) 8,57 g 0,1 mg 0,1765
H02AB Glucocorticoids 9,6852
H02AB01 Betamethasone (P) 15,1965 g 1,5 mg 0,0209
H02AB02 Dexamethasone (O) 1398,13 g 1,5 mg 1,9200
H02AB02 Dexamethasone (P) 950,2 g 1,5 mg 1,3049
H02AB04 Methylprednisolone (O) 7474 g 7,5 mg 2,0528
H02AB04 Methylprednisolone (P) 4749,35 g 0,02 g 0,4892
H02AB06 Prednisolone (O) 13905 g 0,01 g 2,8644
H02AB06 Prednisolone (P) 1270,85 g 0,01 g 0,2618
H02AB08 Triamcinolone (O) 11,2 g 7,5 mg 0,0031
H02AB08 Triamcinolone (P) 1562,4 g 7,5 mg 0,4291
H02AB09 Hydrocortisone (O) 4251,65 g 0,03 g 0,2919
H02AB09 Hydrocortisone (P) 680,4 g 0,03 g 0,0467
H02AB13 Deflazacort (O) 3 g 15 mg 0,0004
H02B CORTICOSTEROIDS FOR SYSTEMIC USE,
COMBINATIONS 0,0043
H02BX Corticosteroids for systemic use, combinations 0,0043
H02BX80 Hydrocortisone+Lidocaine (P) 56,625 g 0,03 g 0,0039
H02BX81 Methylprednisolone+Bupivacaine (P) 4 g 20 mg 0,0004
H03 THYROID THERAPY 20,8799
H03A THYROID PREPARATIONS 19,6724
H03AA Thyroid hormones 19,6724
H03AA01 Levothyroxine sodium (O) 1432,35 g 0,15 mg 19,6704
H03AA02 Liothyronine (O) 0,058 g 0,06 mg 0,0020
H03AA03 Levothyroxine sodium+Liothyronine (O) 300 pieces
H03AA04 Tiratricol (O) 0,189 g
H03B ANTITHYROID PREPARATIONS 1,2075
H03BA Thiouracils 0,1443
H03BA02 Propylthiouracil (O) 7004,5 g 0,1 g 0,1443
H03BB Sulfur-containing imidazole derivatives 1,0632
H03BB02 Thiamazole (O) 5161,5 g 0,01 g 1,0632
H03BC Perchlorates
H03BC01 Sodium perchlorate (O) 72 g
H04 PANCREATIC HORMONES 0,0010
H04A GLYCOGENOLYTIC HORMONES 0,0010
H04AA Glycogenolytic hormones 0,0010
H04AA01 Glucagon (P) 0,47 g 0,001 g 0,0010
H05 CALCIUM HOMEOSTASIS 0,0440
H05B ANTI-PARATHYROID AGENTS 0,0440
H05BX Other anti-parathyroid agents 0,0440
H05BX01 Cinacalcet (O) 1276,8 g 0,06 g 0,0438
H05BX02 Paricalcitol (O) 0,0001 g 2 mcg 0,0001
J ANTIINFECTIVES FOR SYSTEMIC USE 17,7055
J01 ANTIBACTERIALS FOR SYSTEMIC USE 10,0665
J01A TETRACYCLINES 1,3317
J01AA Tetracyclines 1,3317
J01AA02 Doxycycline (O) 64635 g 0,1 g 1,3314
J01AA02 Doxycycline (P) 3,5 g 0,1 g 0,0001
J01AA07 Tetracycline (O) 5 g 1 g <0,0001
J01AA12 Tigecycline (P) 8 g 0,1 g 0,0002
J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS 3,7400
J01CA Penicillins with extended spectrum 1,2931
J01CA01 Ampicillin (P) 18100 g 6 g 0,0062
18/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J01CA04 Amoxicillin (O) 937090,5 g 1,5 g 1,2869
J01CE Beta-lactamase sensitive penicillins 0,0914
J01CE01 Benzylpenicillin (P) 29160 g 3,6 g 0,0167
J01CE02 Phenoxymethylpenicillin (O) 71629,8 g 2 g 0,0738
J01CE08 Benzathine benzylpenicillin (P) 1638 g 3,6 g 0,0009
J01CE80 Benzathine benzylpenicillin+Procaine benzylpenicillin (P) 17,1 g 3,6 g <0,0001
J01CF Beta-lactamase resistant penicillins 0,0814
J01CF04 Oxacillin (P) 78940 g 2 g 0,0813
J01CF05 Flucloxacillin (O) 120 g 2 g 0,0001
J01CR Combinations of penicillins, incl. beta-lactamase inhibitors 2,2741
J01CR01 Ampicillin+Sulbactam (P) 53366 g 6 g 0,0183
J01CR02 Amoxicillin+Clavulanic acid (O) 1415868,3 g 1,5 g 1,9444
J01CR02 Amoxicillin+Clavulanic acid (P) 300895 g 3 g 0,2066
J01CR04 Sultamicillin (O) 40374 g 1,5 g 0,0554
J01CR05 Piperacillin+Tazobactam (P) 334928 g 14 g 0,0493
J01D OTHER BETA-LACTAM ANTIBACTERIALS 1,3922
J01DB First-generation cephalosporins 0,1960
J01DB01 Cefalexin (O) 30 g 2 g <0,0001
J01DB04 Cefazolin (P) 94420 g 3 g 0,0648
J01DB05 Cefadroxil (O) 127335 g 2 g 0,1312
J01DC Second-generation cephalosporins 1,0486
J01DC01 Cefoxitin (P) 12305 g 6 g 0,0042
J01DC02 Cefuroxime (O) 206940,25 g 0,5 g 0,8526
J01DC02 Cefuroxime (P) 227040 g 3 g 0,1559
J01DC10 Cefprozil (O) 17427,5 g 1 g 0,0359
J01DD Third-generation cephalosporins 0,0559
J01DD01 Cefotaxime (P) 51070 g 4 g 0,0263
J01DD02 Ceftazidime (P) 11703 g 4 g 0,0060
J01DD04 Ceftriaxone (P) 19970 g 2 g 0,0206
J01DD81 Ceftazidime+Avibactam (P) 8700 g 6 g 0,0030
J01DE Fourth-generation cephalosporins 0,0109
J01DE01 Cefepime (P) 21210 g 4 g 0,0109
J01DH Carbapenems 0,0808
J01DH02 Meropenem (P) 68314 g 3 g 0,0469
J01DH03 Ertapenem (P) 10650 g 1 g 0,0219
J01DH51 Imipenem+Cilastatin (P) 11600 g 2 g 0,0119
J01E SULFONAMIDES AND TRIMETHOPRIM 0,3656
J01EA Trimethoprim and derivatives 0,0295
J01EA01 Trimethoprim (O) 5730 g 0,4 g 0,0295
J01EE Combinations of sulfonamides and trimethoprim, incl.
derivatives 0,3361
J01EE01 Sulfamethoxazole+Trimethoprim (O) 2544 pieces 4 pieces 0,0013
J01EE01 Sulfamethoxazole+Trimethoprim (O) 286130 pieces 2 pieces 0,2947
J01EE01 Sulfamethoxazole+Trimethoprim (O) 623500 ml 40 ml 0,0321
J01EE01 Sulfamethoxazole+Trimethoprim (P) 77445 ml 20 ml 0,0080
J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS 1,8609
J01FA Macrolides 1,6962
J01FA01 Erythromycin (O) 135 g 1 g 0,0003
J01FA01 Erythromycin (P) 80 g 1 g 0,0002
J01FA09 Clarithromycin (O) 281758,5 g 0,5 g 1,1608
J01FA09 Clarithromycin (P) 2873,5 g 1 g 0,0059
J01FA10 Azithromycin (O) 77038,5 g 0,3 g 0,5290
J01FF Lincosamides 0,1648
J01FF01 Clindamycin (O) 89815,2 g 1,2 g 0,1542
J01FF01 Clindamycin (P) 9249 g 1,8 g 0,0106
J01G AMINOGLYCOSIDE ANTIBACTERIALS 0,0218
J01GB Other aminoglycosides 0,0218
J01GB01 Tobramycin (I) 150,528 g 0,112 g 0,0028
J01GB01 Tobramycin (I) 604,8 g 0,3 g 0,0042
J01GB01 Tobramycin (P) 80 g 0,24 g 0,0007
J01GB03 Gentamicin (P) 1217,2 g 0,24 g 0,0104
J01GB06 Amikacin (P) 1825 g 1 g 0,0038
19/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J01M QUINOLONE ANTIBACTERIALS 0,7032
J01MA Fluoroquinolones 0,7032
J01MA01 Ofloxacin (O) 3210 g 0,4 g 0,0165
J01MA02 Ciprofloxacin (O) 249480 g 1 g 0,5139
J01MA02 Ciprofloxacin (P) 10306 g 0,8 g 0,0265
J01MA06 Norfloxacin (O) 36384 g 0,8 g 0,0937
J01MA12 Levofloxacin (O) 6210,75 g 0,5 g 0,0256
J01MA12 Levofloxacin (P) 569,5 g 0,5 g 0,0023
J01MA14 Moxifloxacin (O) 4492 g 0,4 g 0,0231
J01MA14 Moxifloxacin (P) 288 g 0,4 g 0,0015
J01X OTHER ANTIBACTERIALS 0,6510
J01XA Glycopeptide antibacterials 0,0281
J01XA01 Vancomycin (P) 27165 g 2 g 0,0280
J01XA02 Teicoplanin (P) 28 g 0,4 g 0,0001
J01XB Polymyxins 0,0023
J01XB01 Colistin (I) 1800000000 U 9000000 U 0,0004
J01XB01 Colistin (I, P) 1590000000 U 9000000 U 0,0004
J01XB01 Colistin (P) 6560000000 U 9000000 U 0,0015
J01XD Imidazole derivatives 0,0284
J01XD01 Metronidazole (P) 20710 g 1,5 g 0,0284
J01XE Nitrofuran derivatives 0,5708
J01XE01 Nitrofurantoin (O) 55422 g 0,2 g 0,5708
J01XX Other antibacterials 0,0213
J01XX01 Fosfomycin (O) 7854 g 3 g 0,0054
J01XX08 Linezolid (O) 5796 g 1,2 g 0,0099
J01XX08 Linezolid (P) 2760 g 1,2 g 0,0047
J01XX09 Daptomycin (P) 169,65 g 0,28 g 0,0012
J02 ANTIMYCOTICS FOR SYSTEMIC USE 0,4090
J02A ANTIMYCOTICS FOR SYSTEMIC USE 0,4090
J02AA Antibiotics 0,0150
J02AA01 Amphotericin (O) 205 g
J02AA01 Amphotericin (P) 255,05 g 0,035 g 0,0150
J02AB Imidazole derivatives 0,0012
J02AB02 Ketoconazole (O) 120 g 0,2 g 0,0012
J02AC Triazole and tetrazole derivatives 0,3822
J02AC01 Fluconazole (O) 15340,3 g 0,2 g 0,1580
J02AC01 Fluconazole (P) 3956 g 0,2 g 0,0407
J02AC02 Itraconazole (O) 13460,2 g 0,2 g 0,1386
J02AC03 Voriconazole (O) 2920,4 g 0,4 g 0,0150
J02AC03 Voriconazole (P) 616,6 g 0,4 g 0,0032
J02AC04 Posaconazole (O) 2764,2 g 0,3 g 0,0190
J02AC04 Posaconazole (P) 688,8 g 0,3 g 0,0047
J02AC05 Isavuconazole (O) 168 g 0,2 g 0,0017
J02AC05 Isavuconazole (P) 110,8 g 0,2 g 0,0011
J02AX Other antimycotics for systemic use 0,0105
J02AX04 Caspofungin (P) 63,61 g 0,05 g 0,0026
J02AX06 Anidulafungin (P) 383,8 g 0,1 g 0,0079
J04 ANTIMYCOBACTERIALS 0,0664
J04A DRUGS FOR TREATMENT OF TUBERCULOSIS 0,0516
J04AB Antibiotics 0,0154
J04AB02 Rifampicin (O) 4429,2 g 0,6 g 0,0152
J04AB02 Rifampicin (P) 63 g 0,6 g 0,0002
J04AC Hydrazides 0,0154
J04AC01 Isoniazid (O) 2250 g 0,3 g 0,0154
J04AD Thiocarbamide derivatives 0,0055
J04AD01 Protionamide (O) 2000 g 0,75 g 0,0055
J04AK Other drugs for treatment of tuberculosis 0,0115
J04AK05 Bedaquiline (O) 376 g 86 mg 0,0090
J04AK06 Delamanid (O) 240 g 0,2 g 0,0025
J04AK08 Pretomanid (O) 291,2 g
J04AM Combinations of drugs for treatment of tuberculosis 0,0037
J04AM02 Rifampicin+Isoniazid (O) 7200 pieces 4 pieces 0,0037
20/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J04B DRUGS FOR TREATMENT OF LEPRA 0,0148
J04BA Drugs for treatment of lepra 0,0148
J04BA02 Dapsone (O) 360 g 0,05 g 0,0148
J05 ANTIVIRALS FOR SYSTEMIC USE 7,1637
J05A DIRECT ACTING ANTIVIRALS 7,1637
J05AB Nucleosides and nucleotides excl. reverse transcriptase
inhibitors 0,4540
J05AB01 Aciclovir (O) 388037 g 4 g 0,1998
J05AB01 Aciclovir (P) 2876,25 g 4 g 0,0015
J05AB06 Ganciclovir (P) 419,5 g 0,5 g 0,0017
J05AB09 Famciclovir (O) 189 g 0,75 g 0,0005
J05AB11 Valaciclovir (O) 280250 g 3 g 0,1924
J05AB12 Cidofovir (P) 1,125 g 0,025 g 0,0001
J05AB14 Valganciclovir (O) 6355 g 0,9 g 0,0145
J05AB16 Remdesivir (P) 2105 g 0,1 g 0,0434
J05AD Phosphonic acid derivatives 0,0001
J05AD01 Foscarnet sodium (P) 360 g 6,5 g 0,0001
J05AE Protease inhibitors 1,0143
J05AE03 Ritonavir (O) 94131 g 1,2 g 0,1616
J05AE10 Darunavir (O) 496728 g 1,2 g 0,8527
J05AF Nucleoside and nucleotide reverse transcriptase inhibitors 0,1327
J05AF01 Zidovudine (O) 292 g 0,6 g 0,0010
J05AF01 Zidovudine (P) 93 g 0,6 g 0,0003
J05AF05 Lamivudine (O) 575,4 g 0,3 g 0,0040
J05AF06 Abacavir (O) 2582,4 g 0,6 g 0,0089
J05AF07 Tenofovir disoproxil (O) 499,8 g 0,245 g 0,0042
J05AF10 Entecavir (O) 26,19 g 0,5 mg 0,1079
J05AF13 Tenofovir alafenamide (O) 78 g 25 mg 0,0064
J05AG Non-nucleoside reverse transcriptase inhibitors 0,8506
J05AG05 Rilpivirine (O) 10323 g 25 mg 0,8506
J05AH Neuraminidase inhibitors 0,0134
J05AH02 Oseltamivir (O) 974,25 g 0,15 g 0,0134
J05AJ Integrase inhibitors 1,2941
J05AJ01 Raltegravir (O) 473544 g 0,8 g 1,2193
J05AJ03 Dolutegravir (O) 1813,5 g 50 mg 0,0747
J05AP Antivirals for treatment of HCV infections 0,1925
J05AP54 Elbasvir+Grazoprevir (O) 43092 pieces 1 pieces 0,0888
J05AP55 Sofosbuvir+Velpatasvir (O) 2856 pieces 1 pieces 0,0059
J05AP57 Glecaprevir+Pibrentasvir (O) 142464 pieces 3 pieces 0,0978
J05AR Antivirals for treatment of HIV infections, combinations 3,2121
J05AR02 Lamivudine+Abacavir (O) 335190 pieces 1 pieces 0,6905
J05AR03 Tenofovir disoproxil+Emtricitabine (O) 825960 pieces 1 pieces 1,7014
J05AR06 Emtricitabine+Tenofovir disoproxil+Efavirenz (O) 134910 pieces 1 pieces 0,2779
J05AR13 Lamivudine+Abacavir+Dolutegravir (O) 262650 pieces 1 pieces 0,5410
J05AR18 Emtricitabine+Tenofovir alafenamide+Elvitegravir+Cobicistat
(O) 600 pieces 1 pieces 0,0012
J06 IMMUNE SERA AND IMMUNOGLOBULINS
J06A IMMUNE SERA
J06AA Immune sera
J06AA04 Botulinum antitoxin (P) 35 pieces
J06B IMMUNOGLOBULINS
J06BA Immunoglobulins, normal human
J06BA01 Immunoglobulins, normal human, for extravascular a (P) 11217,9 g
J06BA02 Immunoglobulins, normal human, for intravascular a (P) 106802,5 g
J06BB Specific immunoglobulins
J06BB01 Human Anti-D Immunoglobulin (P) 1866375 U
J06BB02 Tetanus immunoglobulin (P) 43000 U
J06BB03 Varicella zoster immunoglobulin (P) 6250 U
J06BB04 Hepatitis B immunoglobulin (P) 6800 U
J06BB05 Rabies immunoglobulin (P) 3000 U
J06BB09 Cytomegalovirus immunoglobulin (P) 70000 U
J06BB82 Regdanvimab (P) 192 g
21/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J06BD Antiviral monoclonal antibodies
J06BD01 Palivizumab (P) 42,45 g
J07 VACCINES
J07A BACTERIAL VACCINES
J07AE Cholera vaccines
J07AE01 Cholera, inactivated, whole cell (O) 84 doses
J07AG Hemophilus influenzae B vaccines
J07AG01 Haemophilus influenzae B, purified antigen conjugated (P) 229 doses
J07AH Meningococcal vaccines
J07AH08 Meningococcus, tetravalent purified polysaccharides antigen
conjugated (P) 453 doses
J07AH09 Meningococcus B, multicomponent vaccine (P) 46 doses
J07AL Pneumococcal vaccines
J07AL01 Pneumococcus, purified polysaccharides antigen (P) 553 doses
J07AL02 Pneumococcus, purified polysaccharides antigen conjugated
(P) 2391 doses
J07AL52 Pneumococcus, purified polysaccharides
antigen+Haemophilus influenzae, conjugated (P) 209 doses
J07AM Tetanus vaccines
J07AM51 Tetanus toxoid+Diphtheria toxoid (P) 48673 doses
J07AN Tuberculosis vaccines
J07AN01 Tuberculosis, live attenuated (P) 2622 pieces
J07AP Typhoid vaccines
J07AP03 Typhoid, purified polysaccharide antigen (P) 737 doses
J07AX Other bacterial vaccines
J07AX80 Diphtheria-tetanus-pertussis (P) 10784 doses
J07B VIRAL VACCINES
J07BA Encephalitis vaccines
J07BA01 Encephalitis, tick borne, inactivated, whole virus (P) 72311 doses
J07BB Influenza vaccines
J07BB02 Influenza, inactivated, split virus or surface antigen (P) 201317 doses
J07BB03 Influenza, live attenuated (N) 2830 doses
J07BC Hepatitis vaccines
J07BC01 Hepatitis B, purified antigen (P) 2316 doses
J07BC02 Hepatitis A, inactivated, whole virus (P) 1490 doses
J07BC80 Hepatitis A, inactivated, whole virus+Hepatitis B, purified
antigen (P) 1037 doses
J07BD Measles vaccines
J07BD52 Measles, live attunated+Rubella, live attenuated+Mumps,
live,attenuated (P) 23986 doses
J07BF Poliomyelitis vaccines
J07BF03 Poliomyelitis, trivalent, inactivated, whole virus (P) 533 doses
J07BG Rabies vaccines
J07BG01 Rabies, inactivated, whole virus (P) 1377 doses
J07BH Rota virus diarrhea vaccines
J07BH02 Rota virus, pentavalent, live, reassorted (O) 79845 doses
J07BK Varicella zoster vaccines
J07BK01 Varicella, live attenuated (P) 1838 doses
J07BK02 Zoster, live attenuated (P) 44 doses
J07BK03 Zoster, purified antigen (P) 4 doses
J07BL Yellow fever vaccines
J07BL01 Yellow fever, live attenuated (P) 711 doses
J07BM Papillomavirus vaccines
J07BM02 Papillomavirus (human types 16, 18) (P) 1 doses
J07BM03 Papillomavirus (human types 6, 11, 16, 18, 31, 33, 45, 52, 58)
(P) 15319 doses
J07BX Other viral vaccines
J07BX03 Covid-19 vaccine (P) 2115397,2 doses
J07C BACTERIAL AND VIRAL VACCINES, COMBINED
J07CA Bacterial and viral vaccines, combined
J07CA02 Diphtheria toxoid+Pertussis, purified antigen+Tetanus
toxoid+Poliomyelitis, trivalent, inactivated, whole virus (P) 16332 doses
22/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J07CA06
Diphtheria toxoid+Tetanus toxoid+Pertussis, purified
antigen+Poliomyelitis, trivalent, inactivated, whole
virus+Haemophilus influenzae B, purified antigen conjugated
(P)
455 doses
J07CA09
Diphtheria toxoid+Poliomyelitis, trivalent, inactivated, whole
virus+Pertussis, purified antigen+Haemophilus influenzae B,
purified antigen conjugated+Hepatitis B, purified
antigen+Tetanus toxoid (P)
47370 doses
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS 13,0308
L01 ANTINEOPLASTIC AGENTS 0,4860
L01A ALKYLATING AGENTS
L01AA Nitrogen mustard analogues
L01AA01 Cyclophosphamide (O) 660 g
L01AA01 Cyclophosphamide (P) 3690 g
L01AA02 Chlorambucil (O) 18,85 g
L01AA03 Melphalan (O) 4,5 g
L01AA03 Melphalan (P) 21,75 g
L01AA06 Ifosfamide (P) 1995 g
L01AA09 Bendamustine (P) 150,4 g
L01AB Alkyl sulfonates
L01AB01 Busulfan (O) 4 g
L01AB01 Busulfan (P) 1,92 g
L01AB02 Treosulfan (P) 1530 g
L01AC Ethylene imines
L01AC01 Thiotepa (P) 1,965 g
L01AD Nitrosoureas
L01AD01 Carmustine (P) 6,3 g
L01AD02 Lomustine (O) 22,4 g
L01AD04 Streptozocin (P) 16 g
L01AX Other alkylating agents
L01AX03 Temozolomide (O) 668,8 g
L01AX04 Dacarbazine (P) 415 g
L01B ANTIMETABOLITES
L01BA Folic acid analogues
L01BA01 Methotrexate (P) 1165,2 g
L01BA04 Pemetrexed (P) 365 g
L01BB Purine analogues
L01BB02 Mercaptopurine (O) 448,75 g
L01BB03 Tioguanine (O) 6 g
L01BB04 Cladribine (P) 0,42 g
L01BB05 Fludarabine (P) 19,5 g
L01BB06 Clofarabine (P) 1,1 g
L01BC Pyrimidine analogues
L01BC01 Cytarabine (P) 2136 g
L01BC02 Fluorouracil (C) 80 g
L01BC02 Fluorouracil (P) 13025 g
L01BC05 Gemcitabine (P) 5081,4348 g
L01BC06 Capecitabine (O) 256872 g
L01BC07 Azacitidine (P) 315 g
L01BC82 Fluorouracil+Salicylic acid (C) 150 ml
L01BC83 Trifluridine+Tipiracil (O) 16380 pieces
L01C PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS
L01CA Vinca alkaloids and analogues
L01CA01 Vinblastine (P) 2,91 g
L01CA02 Vincristine (P) 2,233 g
L01CA03 Vindesine (P) 0,005 g
L01CA04 Vinorelbine (O) 6,38 g
L01CA04 Vinorelbine (P) 19,55 g
L01CB Podophyllotoxin derivatives
L01CB01 Etoposide (O) 275 g
L01CB01 Etoposide (P) 461,2 g
23/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01CD Taxanes
L01CD01 Paclitaxel (P) 813,2 g
L01CD02 Docetaxel (P) 469,12 g
L01CD04 Cabazitaxel (P) 1,32 g
L01CE Topoisomerase 1 (TOP1) inhibitors
L01CE01 Topotecan (P) 2,12 g
L01CE02 Irinotecan (P) 630 g
L01CX Other plant alkaloids and natural products
L01CX01 Trabectedin (P) 0,009 g
L01D CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
L01DA Actinomycines
L01DA01 Dactinomycin (P) 0,052 g
L01DB Anthracyclines and related substances
L01DB01 Doxorubicin (P) 148,84 g
L01DB02 Daunorubicin (P) 8,12 g
L01DB03 Epirubicin (P) 188,8 g
L01DB06 Idarubicin (P) 1,4 g
L01DB07 Mitoxantrone (P) 0,82 g
L01DC Other cytotoxic antibiotics
L01DC01 Bleomycin (P) 6960000 U
L01DC03 Mitomycin (P) 4,22 g
L01E PROTEIN KINASE INHIBITORS 0,4860
L01EA BCR-ABL tyrosine kinase inhibitors 0,1211
L01EA01 Imatinib (O) 14400 g 0,4 g 0,0742
L01EA02 Dasatinib (O) 663 g 0,1 g 0,0137
L01EA03 Nilotinib (O) 8534,4 g 0,6 g 0,0293
L01EA04 Bosutinib (O) 551,6 g 0,4 g 0,0028
L01EA05 Ponatinib (O) 24,3 g 45 mg 0,0011
L01EB Epidermal growth factor receptor (EGFR) tyrosine kinase
inhibitors 0,0258
L01EB01 Gefitinib (O) 1665 g 0,25 g 0,0137
L01EB02 Erlotinib (O) 48 g 0,15 g 0,0007
L01EB03 Afatinib (O) 73,36 g 40 mg 0,0038
L01EB04 Osimertinib (O) 295,2 g 80 mg 0,0076
L01EC B-Raf serine-threonine kinase (BRAF) inhibitors 0,0205
L01EC02 Dabrafenib (O) 2979 g 0,3 g 0,0205
L01ED Anaplastic lymphoma kinase (ALK) inhibitors 0,0055
L01ED01 Crizotinib (O) 315 g 0,5 g 0,0013
L01ED02 Ceritinib (O) 315 g 0,45 g 0,0014
L01ED03 Alectinib (O) 974,4 g 1,2 g 0,0017
L01ED04 Brigatinib (O) 93,24 g 0,18 g 0,0011
L01EE Mitogen-activated protein kinase (MEK) inhibitors 0,0220
L01EE01 Trametinib (O) 21,36 g 2 mg 0,0220
L01EE04 selumetinib (O) 2,1 g
L01EF Cyclin-dependent kinase (CDK) inhibitors 0,0711
L01EF01 Palbociclib (O) 2657,025 g 94 mg 0,0582
L01EF02 Ribociclib (O) 2809,8 g 0,45 g 0,0129
L01EG Mammalian target of rapamycin (mTOR) kinase inhibitors 0,0101
L01EG01 Temsirolimus (P) 0,36 g 3,57 mg 0,0002
L01EG02 Everolimus (O) 48 g 10 mg 0,0099
L01EH Human epidermal growth factor receptor 2 (HER2) tyrosine
kinase inhibitors 0,0009
L01EH01 Lapatinib (O) 420 g 1,25 g 0,0007
L01EH03 Tucatinib (O) 54 g 0,6 g 0,0002
L01EJ Janus-associated kinase (JAK) inhibitors 0,0175
L01EJ01 Ruxolitinib (O) 254,8 g 30 mg 0,0175
L01EK Vascular endothelial growth factor receptor (VEGFR) tyrosine
kinase inhibitors 0,0050
L01EK01 Axitinib (O) 24,304 g 10 mg 0,0050
L01EL Bruton's tyrosine kinase (BTK) inhibitors 0,0521
L01EL01 Ibrutinib (O) 10617,6 g 0,42 g 0,0521
L01EX Other protein kinase inhibitors 0,1346
24/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01EX01 Sunitinib (O) 325,5 g 33 mg 0,0203
L01EX02 Sorafenib (O) 3718,4 g 0,8 g 0,0096
L01EX03 Pazopanib (O) 15234 g 0,8 g 0,0392
L01EX05 regorafenib (O) 201,6 g 0,12 g 0,0035
L01EX07 Cabozantinib (O) 477,72 g 60 mg 0,0164
L01EX08 Lenvatinib (O) 87,06 g 18 mg 0,0100
L01EX09 Nintedanib (O) 6126 g 0,38 g 0,0332
L01EX10 Midostaurin (O) 119 g 0,1 g 0,0025
L01F MONOCLONAL ANTIBODIES AND ANTIBODY DRUG
CONJUGATES
L01FA CD20 (Clusters of Differentiation 20) inhibitors
L01FA01 Rituximab (P) 2036,856 g
L01FA03 Obinutuzumab (P) 50 g
L01FB CD22 (Clusters of Differentiation 22) inhibitors
L01FB01 Inotuzumab ozogamicin (P) 0,016 g
L01FC CD38 (Clusters of Differentiation 38) inhibitors
L01FC01 Daratumumab (P) 760,6 g
L01FD HER2 (Human Epidermal Growth Factor Receptor 2)
inhibitors
L01FD01 Trastuzumab (P) 1632,15 g
L01FD02 Pertuzumab (P) 255,78 g
L01FD03 Trastuzumab emtansine (P) 124,72 g
L01FE EGFR (Epidermal Growth Factor Receptor) inhibitors
L01FE01 Cetuximab (P) 19,6 g
L01FE02 Panitumumab (P) 109,3 g
L01FF PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1)
inhibitors
L01FF01 Nivolumab (P) 294,72 g
L01FF02 Pembrolizumab (P) 438 g
L01FF03 Durvalumab (P) 318,5 g
L01FF05 Atezolizumab (P) 524,4 g
L01FG VEGF/VEGFR (Vascular Endothelial Growth Factor) inhibitors
L01FG01 Bevacizumab (P) 1214,5 g
L01FG02 Ramucirumab (P) 2,8 g
L01FX Other monoclonal antibodies and antibody drug conjugates
L01FX04 Ipilimumab (P) 2,7 g
L01FX05 Brentuximab vedotin (P) 13,1 g
L01FX07 Blinatumomab (P) 0,004 g
L01FX14 polatuzumab vedotin (P) 0,51 g
L01FX18 Amivantamab (P) 6,3 g
L01X OTHER ANTINEOPLASTIC AGENTS
L01XA Platinum compounds
L01XA01 Cisplatin (P) 174 g
L01XA02 Carboplatin (P) 2049 g
L01XA03 Oxaliplatin (P) 860 g
L01XB Methylhydrazines
L01XB01 Procarbazine (O) 262,5 g
L01XD Sensitizers used in photodynamic/radiation therapy
L01XD04 Aminolevulinic acid (O) 18 g
L01XF Retinoids for cancer treatment
L01XF01 Tretinoin (O) 9 g
L01XG Proteasome inhibitors
L01XG01 Bortezomib (P) 8,7465 g
L01XG02 Carfilzomib (P) 10,26 g
L01XK Poly (ADP-ribose) polymerase (PARP) inhibitors
L01XK01 Olaparib (O) 10761,6 g
L01XX Other antineoplastic agents
L01XX02 Asparaginase (P) 2550000 U
L01XX05 Hydroxycarbamide (O) 254750 g
L01XX11 Estramustine (O) 72,8 g
L01XX23 Mitotane (O) 3600 g
25/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01XX24 Pegaspargase (P) 281250 U
L01XX27 Arsenic trioxide (P) 0,3 g
L01XX35 Anagrelide (O) 1,65 g
L01XX41 Eribulin (P) 0,3687 g
L01XX52 Venetoclax (O) 3938,48 g
L01XX73 Sotorasib (O) 172,8 g
L01XY Combinations of antineoplastic agents
L01XY02 Pertuzumab+Trastuzumab (P) 3445 ml
L02 ENDOCRINE THERAPY 4,7394
L02A HORMONES AND RELATED AGENTS 0,7576
L02AB Progestogens 0,0118
L02AB02 Medroxyprogesterone (O) 5745 g 1 g 0,0118
L02AE Gonadotropin releasing hormone analogues 0,7458
L02AE03 Goserelin (P) 9,2952 g 0,129 mg 0,1484
L02AE04 Triptorelin (P) 0,3108 g 0,1 mg 0,0064
L02AE04 Triptorelin (P) 38,4412 g 0,134 mg 0,5909
L02B HORMONE ANTAGONISTS AND RELATED AGENTS 3,9817
L02BA Anti-estrogens 0,8024
L02BA01 Tamoxifen (O) 6112,2 g 0,02 g 0,6295
L02BA03 Fulvestrant (P) 696,5 g 8,3 mg 0,1729
L02BB Anti-androgens 1,1581
L02BB03 Bicalutamide (O) 27742,4 g 0,05 g 1,1430
L02BB04 enzalutamide
(O) 1061,76 g 0,16 g 0,0137
L02BB05 Apalutamide (O) 172,8 g 0,24 g 0,0015
L02BG Aromatase inhibitors 1,9004
L02BG03 Anastrozole (O) 340,944 g 1 mg 0,7023
L02BG04 Letrozole (O) 1312,95 g 2,5 mg 1,0818
L02BG06 Exemestane (O) 1410,75 g 0,025 g 0,1162
L02BX Other hormone antagonists and related agents 0,1208
L02BX03 Abiraterone (O) 58650 g 1 g 0,1208
L03 IMMUNOSTIMULANTS 0,5084
L03A IMMUNOSTIMULANTS 0,5084
L03AA Colony stimulating factors 0,0976
L03AA02 Filgrastim (P) 9,7851 g 0,35 mg 0,0576
L03AA13 Pegfilgrastim (P) 5,826 g 0,3 mg 0,0400
L03AB Interferons 0,2994
L03AB04 Interferon alfa-2a (P) 1230000000 U 2000000 U 0,0013
L03AB07 Interferon beta-1a (P) 0,4547 g 0,0043 mg 0,2178
L03AB08 Interferon beta-1b (P) 72960000000 U 4000000 U 0,0376
L03AB11 Peginterferon alfa-2a (P) 0,035 g 0,026 mg 0,0028
L03AB13 Peginterferon beta-1a (P) 0,1726 g 8,9 mcg 0,0400
L03AX Other immunostimulants 0,1114
L03AX03 BCG bacteria (P) 4,175 g 1,8 mg 0,0048
L03AX13 Glatiramer acetate (P) 1029,6 g 0,02 g 0,1060
L03AX15 Mifamurtide (P) 0,192 g 0,7 mg 0,0006
L03AX16 Plerixafor (P) 0,456 g 16,8 mg 0,0001
L03AX80 Methyluracil (R) 300 g
L04 IMMUNOSUPPRESSANTS 7,2970
L04A IMMUNOSUPPRESSANTS 7,2970
L04AA Selective immunosuppressants 1,2287
L04AA03 Antilymphocyte immunoglobulin (horse) (P) 10 g
L04AA04 Rabbit anti-T-lymphocyte immunoglobulin (P) 20,65 g 0,1 g 0,0004
L04AA06 Mycophenolic acid (O) 290647,6 g 2 g 0,2994
L04AA06 Mycophenolic acid (P) 146 g 2 g 0,0002
L04AA10 Sirolimus (O) 23,67 g 0,003 g 0,0163
L04AA13 Leflunomide (O) 5487,3 g 0,02 g 0,5652
L04AA18 Everolimus (O) 0,36 g 1,5 mg 0,0005
L04AA23 Natalizumab (P) 45,9 g 0,01 g 0,0095
L04AA24 Abatacept (P) 202,25 g 0,027 g 0,0154
L04AA25 Eculizumab (P) 79,8 g 0,064 g 0,0026
L04AA26 Belimumab (P) 5,6 g 25 mg 0,0005
26/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L04AA27 Fingolimod (O) 3,99 g 0,5 mg 0,0164
L04AA29 Tofacitinib
(O) 124,992 g 10 mg 0,0257
L04AA31 Teriflunomide (O) 700,504 g 14 mg 0,1031
L04AA33 Vedolizumab (P) 96,612 g 5,4 mg 0,0369
L04AA34 Alemtuzumab (P) 0,84 g 0,13 mg 0,0133
L04AA36 Ocrelizumab (P) 130,5 g 3,29 mg 0,0817
L04AA37 Baricitinib
(O) 3,92 g 4 mg 0,0020
L04AA40 Cladribine (O) 1,81 g 0,34 mg 0,0110
L04AA42 Siponimod (O) 15,354 g
L04AA44 Upadacitinib (O) 209,58 g 15 mg 0,0288
L04AA47 Inebilizumab (P) 1,2 g
L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors 1,4872
L04AB01 Etanercept (P) 1009 g 0,007 g 0,2969
L04AB02 Infliximab (P) 1013,3 g 3,75 mg 0,5566
L04AB04 Adalimumab (P) 757,4 g 2,9 mg 0,5380
L04AB05 Certolizumab pegol (P) 28,8 g 14 mg 0,0042
L04AB06 Golimumab (P) 73,65 g 1,66 mg 0,0914
L04AC Interleukin inhibitors 0,5350
L04AC02 Basiliximab (P) 1,44 g 0,04 g 0,0001
L04AC03 Anakinra (P) 59,7975 g 0,1 g 0,0012
L04AC05 Ustekinumab (P) 59,43 g 0,54 mg 0,2267
L04AC07 Tocilizumab (P) 1524,376 g 0,02 g 0,1570
L04AC10 Secukinumab (P) 451,05 g 10 mg 0,0929
L04AC13 Ixekizumab (P) 21,12 g 2,9 mg 0,0150
L04AC14 Sarilumab (P) 131,1 g 14,3 mg 0,0189
L04AC16 Guselkumab (P) 7,9 g 1,79 mg 0,0091
L04AC18 Risankizumab (P) 11,4 g 1,67 mg 0,0141
L04AD Calcineurin inhibitors 0,4489
L04AD01 Ciclosporin (O) 26942,5 g 0,25 g 0,2220
L04AD01 Ciclosporin (P) 95 g 0,25 g 0,0008
L04AD02 Tacrolimus (O) 548,6025 g 5 mg 0,2260
L04AD02 Tacrolimus (P) 0,3 g 5 mg 0,0001
L04AX Other immunosuppressants 3,5973
L04AX01 Azathioprine (O) 29980 g 0,15 g 0,4117
L04AX02 Thalidomide (O) 313,6 g 0,1 g 0,0065
L04AX03 Methotrexate (O) 3341,8 g 2,5 mg 2,7536
L04AX03 Methotrexate (P) 139,95 g 2,5 mg 0,1153
L04AX04 Lenalidomide (O) 427,77 g 0,01 g 0,0881
L04AX05 Pirfenidone (O) 19512,36 g 2,4 g 0,0167
L04AX06 Pomalidomide
(O) 18,144 g 3 mg 0,0125
L04AX07 Dimethyl fumarate (O) 44943,36 g 0,48 g 0,1929
M MUSCULO-SKELETAL SYSTEM 84,8775
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS 68,4088
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS,
NON-STEROIDS 68,3974
M01AB Acetic acid derivatives and related substances 8,5761
M01AB01 Indometacin (O) 2065,2 g 0,1 g 0,0425
M01AB05 Diclofenac (O) 294447 g 0,1 g 6,0654
M01AB05 Diclofenac (P) 7798,5 g 0,1 g 0,1606
M01AB05 Diclofenac (R) 12623,375 g 0,1 g 0,2600
M01AB15 Ketorolac (P) 1,8 g 30 mg 0,0001
M01AB16 Aceclofenac (O) 42012 g 0,2 g 0,4327
M01AB82 Diclofenac+Omeprazole (O) 78381 g 0,1 g 1,6146
M01AC Oxicams 3,6044
M01AC01 Piroxicam (O) 939,6 g 0,02 g 0,0968
M01AC05 Lornoxicam (O) 1962,96 g 0,012 g 0,3370
M01AC06 Meloxicam (O) 22912,2 g 0,015 g 3,1465
M01AC06 Meloxicam (P) 175,725 g 0,015 g 0,0241
27/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
M01AE Propionic acid derivatives 39,5075
M01AE01 Ibuprofen (O) 14553081,2 g 1,2 g 24,9821
M01AE01 Ibuprofen (P) 7830 g 1,2 g 0,0134
M01AE02 Naproxen (O) 697334 g 0,5 g 2,8729
M01AE03 Ketoprofen (O) 123697,375 g 0,15 g 1,6987
M01AE03 Ketoprofen (P) 12086 g 0,15 g 0,1660
M01AE03 Ketoprofen (R) 1,2 g 0,15 g <0,0001
M01AE17 Dexketoprofen (O) 81245,75 g 0,075 g 2,2315
M01AE17 Dexketoprofen (P) 3681,25 g 0,075 g 0,1011
M01AE52 Naproxen+Esomeprazole (O) 1802955 g 0,5 g 7,4280
M01AE82 Ibuprofen+Phenylephrine (O) 7982,4 g 1,2 g 0,0137
M01AG Fenamates 0,0050
M01AG02 Tolfenamic acid (O) 732 g 0,3 g 0,0050
M01AH Coxibs 9,4846
M01AH01 Celecoxib (O) 79634 g 0,2 g 0,8202
M01AH05 Etoricoxib (O) 252367,29 g 60 mg 8,6644
M01AX Other antiinflammatory and antirheumatic agents, non-steroids 7,2198
M01AX01 Nabumetone (O) 153000 g 1 g 0,3152
M01AX05 Glucosamine (O) 5027748,69 g 1,5 g 6,9046
M01C SPECIFIC ANTIRHEUMATIC AGENTS 0,0114
M01CC Penicillamine and similar agents 0,0114
M01CC01 Penicillamine (O) 2775 g 0,5 g 0,0114
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA10 Ketoprofen (C) 1330650 g
M02AA12 Naproxen (C) 1004135 g
M02AA13 Ibuprofen (C) 26462 pieces
M02AA13 Ibuprofen (C) 810500 g
M02AA15 Diclofenac (C) 482007 pieces
M02AA15 Diclofenac (C) 30657500 g
M02AA81 Ibuprofen+Levomenthol (C) 1867700 g
M02AC Preparations with salicylic acid derivatives
M02AC80 Methyl salicylate+Levomenthol+Eucalyptus oil+Turpentine oil
(C) 93063 g
M02AX Other topical products for joint and muscular pain
M02AX80 Nicoboxil+Nonivamide (C) 101340 g
M02AX90 Camphor+Salicylic acid+Turpentine oil+Venenum Viperae
berus (C) 836050 g
M02AX92 Benzyl nicotinate+Nonivamide+Camphor+Turpentine
oil+Dimethyl sulfoxide (C) 737300 g
M03 MUSCLE RELAXANTS 1,0042
M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
M03AB Choline derivatives
M03AB01 Suxamethonium chloride (P) 2881 g
M03AC Other quaternary ammonium compounds
M03AC04 Atracurium besilate (P) 3034,75 g
M03AC06 Pipecuronium bromide (P) 17,5 g
M03AC09 Rocuronium bromide (P) 1072 g
M03AX Other muscle relaxants, peripherally acting agents
M03AX01 Botulinum toxin (P) 1922300 U
M03B MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS 1,0042
M03BX Other centrally acting agents 1,0042
M03BX01 Baclofen (O) 4710,75 g 0,05 g 0,1941
M03BX01 Baclofen (P) 3,9608 g 0,55 mg 0,0148
M03BX02 Tizanidine (O) 4632,9 g 0,012 g 0,7953
M03C MUSCLE RELAXANTS, DIRECTLY ACTING AGENTS
M03CA Dantrolene and derivatives
M03CA01 Dantrolene (P) 3,12 g
M04 ANTIGOUT PREPARATIONS 10,6963
28/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
M04A ANTIGOUT PREPARATIONS 10,6963
M04AA Preparations inhibiting uric acid production 10,6778
M04AA01 Allopurinol (O) 1504129 g 0,4 g 7,7461
M04AA03 Febuxostat (O) 113856,96 g 0,08 g 2,9317
M04AB Preparations increasing uric acid excretion 0,0038
M04AB01 Probenecid (O) 50 g 1 g 0,0001
M04AB03 Benzbromarone (O) 180 g 0,1 g 0,0037
M04AC Preparations with no effect on uric acid metabolism 0,0147
M04AC01 Colchicine (O) 7,15 g 1 mg 0,0147
M05 DRUGS FOR TREATMENT OF BONE DISEASES 4,7681
M05B DRUGS AFFECTING BONE STRUCTURE AND
MINERALIZATION 4,7681
M05BA Bisphosphonates 0,7069
M05BA03 Pamidronic acid (P) 8,13 g 0,06 g 0,0003
M05BA04 Alendronic acid (O) 252 g 0,01 g 0,0519
M05BA06 Ibandronic acid (O) 1212,6 g 0,005 g 0,4996
M05BA06 Ibandronic acid (P) 0,006 g 0,006 g <0,0001
M05BA07 Risedronic acid (O) 357,14 g 0,005 g 0,1471
M05BA08 Zoledronic acid (P) 15,566 g 0,004 g 0,0080
M05BB Bisphosphonates, combinations 2,6112
M05BB03 Alendronic acid+Colecalciferol (O) 12675,88 g 10 mg 2,6112
M05BX Other drugs affecting bone structure and mineralization 1,4500
M05BX04 Denosumab (P) 232,294 g 0,33 mg 1,4500
M05BX05 Burosumab (P) 2,53 g
M09 OTHER DRUGS FOR DISORDERS OF THE MUSCULO-
SKELETAL SYSTEM
M09A OTHER DRUGS FOR DISORDERS OF THE MUSCULO-
SKELETAL SYSTEM
M09AX Other drugs for disorders of the musculo-skeletal system
M09AX10 Risdiplam (O) 0,6 g
N NERVOUS SYSTEM 148,2854
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AB Halogenated hydrocarbons
N01AB06 Isoflurane (I) 7500 ml
N01AB07 Desflurane (I) 63360 ml
N01AB08 Sevoflurane (I) 745250 ml
N01AF Barbiturates, plain
N01AF03 Thiopental (P) 2160 g
N01AH Opioid anesthetics
N01AH01 Fentanyl (I) 18,182 g
N01AH01 Fentanyl (P) 34,298 g
N01AH06 Remifentanil (P) 22,235 g
N01AX Other general anesthetics
N01AX03 Ketamine (P) 2107 g
N01AX07 Etomidate (P) 40,8 g
N01AX10 Propofol (P) 89540,5 g
N01AX13 Nitrous oxide (I) 11170000 ml
N01AX14 Esketamine (P) 1089 g
N01B ANESTHETICS, LOCAL
N01BB Amides
N01BB01 Bupivacaine (Infilt, P) 3211,2 g
N01BB01 Bupivacaine (P) 219,8 g
N01BB02 Lidocaine (endocerv, P) 200 g
N01BB02 Lidocaine (C) 2097 g
N01BB02 Lidocaine (C) 5650 ml
N01BB02 Lidocaine (NA) 20100 ml
N01BB02 Lidocaine (NA) 68722 g
N01BB02 Lidocaine (O) 79772 g
N01BB02 Lidocaine (P) 23476,15 g
N01BB03 Mepivacaine (dental) 1514,7 g
N01BB08 Articaine (P) 0,8 g
29/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N01BB09 Ropivacaine (P) 725,9 g
N01BB80 Articaine+Epinephrine (dental) 943160 ml
N01BB80 Articaine+Epinephrine (O) 602280 ml
N01BB81 Bupivacaine+Epinephrine (P) 82 g
N01BB81 Bupivacaine+Epinephrine (P) 248200 ml
N01BB82 Lidocaine+Epinephrine (dental) 51800 ml
N01BB83 Lidocaine+Prilocaine (C) 72046,5 g
N01BB86 Lidocaine+Chlorhexidine (urethral) 1410375 g
N01BC Esters of benzoic acid
N01BC01 Cocaine (NA) 30 g
N01BX Other local anesthetics
N01BX04 Capsaicin (C) 67,8718 g
N02 ANALGESICS 27,8706
N02A OPIOIDS 9,3531
N02AA Natural opium alkaloids 0,9453
N02AA01 Morphine (O) 5757,9 g 0,1 g 0,1186
N02AA01 Morphine (P) 758 g 0,03 g 0,0520
N02AA05 Oxycodone (O) 23151,3 g 0,075 g 0,6359
N02AA05 Oxycodone (P) 272,6 g 0,03 g 0,0187
N02AA08 Dihydrocodeine (O) 7836,6 g 0,15 g 0,1076
N02AA55 Oxycodone+Naloxone (O) 453,45 g 75 mg 0,0125
N02AB Phenylpiperidine derivatives 0,1259
N02AB02 Pethidine (P) 140,5 g 0,4 g 0,0007
N02AB02 Pethidine (P, V) 1408 g 0,4 g 0,0073
N02AB03 Fentanyl (O) 2,9652 g
N02AB03 Fentanyl (SL) 2,949 g 0,6 mg 0,0101
N02AB03 Fentanyl (TD) 62,8196 g 1,2 mg 0,1078
N02AE Oripavine derivatives 0,0183
N02AE01 Buprenorphine (TD) 10,6814 g 1,2 mg 0,0183
N02AJ Opioids in combination with non-opioid analgesics 6,4965
N02AJ06 Codeine+Paracetamol (O) 7516390 pieces 3 pieces 5,1611
N02AJ13 Tramadol+Paracetamol (O) 2164,5 g 150 mg 0,0297
N02AJ14 Tramadol+Dexketoprofen (O) 95073,75 g 150 mg 1,3056
N02AX Other opioids 1,7670
N02AX02 Tramadol (O) 254279 g 0,3 g 1,7460
N02AX02 Tramadol (P) 3055,25 g 0,3 g 0,0210
N02B OTHER ANALGESICS AND ANTIPYRETICS 17,3768
N02BA Salicylic acid and derivatives 0,9327
N02BA01 Acetylsalicylic acid (O) 1156337,76 g 3 g 0,7940
N02BA01 Acetylsalicylic acid (P) 27 g
N02BA80 Acetylsalicylic acid +Ascorbic acid (O) 201991,2 g 3 g 0,1387
N02BB Pyrazolones 0,0020
N02BB02 Metamizole sodium (O) 50 g 3 g <0,0001
N02BB02 Metamizole sodium (P) 1680 g 3 g 0,0012
N02BB02 Metamizole sodium (P, V) 1190 g 3 g 0,0008
N02BE Anilides 16,4421
N02BE01 Paracetamol (O) 18053987,2 g 3 g 12,3967
N02BE01 Paracetamol (P) 316560 g 3 g 0,2174
N02BE01 Paracetamol (R) 56152,15 g 3 g 0,0386
N02BE52 Paracetamol+Pseudoephedrine+Diphenhydramine (O) 32896 g 3 g 0,0226
N02BE75 Paracetamol+Guaifenesin+Phenylephrine (O) 158191 g 3 g 0,1086
N02BE81 Paracetamol+Chlorphenamine+Pseudoephedrine+Dextrometh
orphan (O) 416918 g 3 g 0,2863
N02BE83 Paracetamol+Caffeine (O) 235272 g 3 g 0,1615
N02BE84 Paracetamol+Phenylephrine+Ascorbic acid (O) 815071,25 g 3 g 0,5597
N02BE85 Paracetamol+Pheniramine+Ascorbic acid (O) 71018,24 g 3 g 0,0488
N02BE86 Paracetamol+Phenylephrine+Terpin hydrate+Ascorbic
acid+Caffeine (O) 268788 g 3 g 0,1846
N02BE87 Paracetamol+Pseudoephedrine (O) 60265 g 3 g 0,0414
N02BE91 Paracetamol+Ascorbic acid (O) 9688,8 g 3 g 0,0067
N02BE92 Paracetamol+Codeine (O) 1253650 g 3 g 0,8608
N02BE94 Paracetamol+Codeine+Caffeine (O) 1786764 g 3 g 1,2269
30/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N02BE95 Paracetamol+Phenylephrine (O) 27820 g 3 g 0,0191
N02BE97 Paracetamol+Pseudoephedrine+Dextromethorphan (O) 382394 g 3 g 0,2626
N02C ANTIMIGRAINE PREPARATIONS 1,1407
N02CC Selective serotonin (5HT1) agonists 1,1117
N02CC01 Sumatriptan (N) 1 g 0,02 g 0,0001
N02CC01 Sumatriptan (O) 23223 g 0,05 g 0,9568
N02CC03 Zolmitriptan (O) 76,47 g 2,5 mg 0,0630
N02CC04 Rizatriptan (O) 56,25 g 0,01 g 0,0116
N02CC07 Frovatriptan (O) 97,325 g 2,5 mg 0,0802
N02CD Calcitonin gene-related peptide (CGRP) antagonists 0,0291
N02CD01 Erenumab (P) 18,55 g 2,5 mg 0,0153
N02CD03 fremanezumab (P) 50,175 g 7,5 mg 0,0138
N03 ANTIEPILEPTICS 12,3166
N03A ANTIEPILEPTICS 12,3166
N03AA Barbiturates and derivatives 0,3440
N03AA02 Phenobarbital (O) 14485 g 0,1 g 0,2984
N03AA02 Phenobarbital (P) 120 g 0,1 g 0,0025
N03AA03 Primidone (O) 26200 g 1,25 g 0,0432
N03AA80 Benzobarbital (O) 90 g
N03AB Hydantoin derivatives 0,0387
N03AB02 Phenytoin (O) 5490 g 0,3 g 0,0377
N03AB02 Phenytoin (P) 147,5 g 0,3 g 0,0010
N03AD Succinimide derivatives 0,0172
N03AD01 Ethosuximide (O) 10425 g 1,25 g 0,0172
N03AE Benzodiazepine derivatives 0,5495
N03AE01 Clonazepam (O) 2133,96 g 0,008 g 0,5495
N03AF Carboxamide derivatives 2,6382
N03AF01 Carbamazepine (O) 878151 g 1 g 1,8089
N03AF02 Oxcarbazepine (O) 401505 g 1 g 0,8271
N03AF03 Rufinamide (O) 1480 g 1,4 g 0,0022
N03AG Fatty acid derivatives 1,6288
N03AG01 Valproic acid (O) 1171350 g 1,5 g 1,6086
N03AG01 Valproic acid (P) 2051,3 g 1,5 g 0,0028
N03AG04 Vigabatrin (O) 16850 g 2 g 0,0174
N03AX Other antiepileptics 7,1003
N03AX03 Sultiame (O) 4770 g 0,4 g 0,0246
N03AX09 Lamotrigine (O) 122867,8 g 0,3 g 0,8437
N03AX11 Topiramate (O) 40113 g 0,3 g 0,2754
N03AX12 Gabapentin (O) 1842411 g 1,8 g 2,1085
N03AX14 Levetiracetam (O) 615172,5 g 1,5 g 0,8448
N03AX14 Levetiracetam (P) 575 g 1,5 g 0,0008
N03AX15 Zonisamide (O) 43,4 g 0,2 g 0,0004
N03AX16 Pregabalin (O) 436014,25 g 0,3 g 2,9939
N03AX17 Stiripentol (O) 1815 g 1 g 0,0037
N03AX18 Lacosamide (O) 68,6 g 0,3 g 0,0005
N03AX22 perampanel (O) 2,016 g 8 mg 0,0005
N03AX23 Brivaracetam (O) 121,8 g 0,1 g 0,0025
N03AX24 Cannabidiol (O) 320 g 0,7 g 0,0009
N04 ANTI-PARKINSON DRUGS 3,6332
N04A ANTICHOLINERGIC AGENTS 0,5502
N04AA Tertiary amines 0,5502
N04AA01 Trihexyphenidyl (O) 2670,9 g 0,01 g 0,5502
N04B DOPAMINERGIC AGENTS 3,0830
N04BA Dopa and dopa derivatives 1,4234
N04BA03 Levodopa +Carbidopa+Entacapone (O) 66452,5 g 0,45 g 0,3042
N04BA80 Levodopa +Benserazide (O) 310370 g 0,6 g 1,0656
N04BA81 Levodopa +Carbidopa (intestin) 22316 g
N04BA81 Levodopa +Carbidopa (O) 15629 g 0,6 g 0,0537
N04BB Adamantane derivatives 0,2933
N04BB01 Amantadine (O) 28480 g 0,2 g 0,2933
N04BB01 Amantadine (P) 16 g
N04BC Dopamine agonists 0,7800
31/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N04BC04 Ropinirole (O) 1097,824 g 0,006 g 0,3769
N04BC05 Pramipexole (O) 462,1697 g 2,5 mg 0,3808
N04BC07 Apomorphine (P) 215,8 g 20 mg 0,0222
N04BD Monoamine oxidase type B inhibitors 0,5863
N04BD02 Rasagiline (O) 284,63 g 0,001 g 0,5863
N05 PSYCHOLEPTICS 45,7687
N05A ANTIPSYCHOTICS 10,1784
N05AA Phenothiazines with aliphatic side-chain 0,1470
N05AA01 Chlorpromazine (O) 10095,5 g 0,3 g 0,0693
N05AA01 Chlorpromazine (P) 33,5 g 0,1 g 0,0007
N05AA02 Levomepromazine (O) 11188 g 0,3 g 0,0768
N05AA02 Levomepromazine (P, V) 8 g 0,1 g 0,0002
N05AB Phenothiazines with piperazine structure 0,0786
N05AB02 Fluphenazine (P) 5,125 g 0,001 g 0,0106
N05AB03 Perphenazine (O) 397,2 g 0,03 g 0,0273
N05AB03 Perphenazine (P) 198,006 g 0,01 g 0,0408
N05AC Phenothiazines with piperidine structure 0,0009
N05AC01 Periciazine (O) 21,6 g 0,05 g 0,0009
N05AD Butyrophenone derivatives 0,8906
N05AD01 Haloperidol (O) 1803,485 g 0,008 g 0,4644
N05AD01 Haloperidol (P) 25 g 0,0033 g 0,0156
N05AD01 Haloperidol (P) 644,25 g 0,008 g 0,1659
N05AD03 Melperone (O) 34075 g 0,3 g 0,2340
N05AD08 Droperidol (P) 13,1 g 2,5 mg 0,0108
N05AE Indole derivatives 0,0804
N05AE03 Sertindole (O) 607,792 g 0,016 g 0,0783
N05AE04 Ziprasidone (O) 81,6 g 0,08 g 0,0021
N05AE05 Lurasidone (O) 1,0416 g 60 mg <0,0001
N05AF Thioxanthene derivatives 0,8348
N05AF01 Flupentixol (O) 347,9 g 0,006 g 0,1194
N05AF01 Flupentixol (P) 116,84 g 0,004 g 0,0602
N05AF03 Chlorprothixene (O) 27282,5 g 0,3 g 0,1873
N05AF05 Zuclopenthixol (O) 1310,5 g 0,03 g 0,0900
N05AF05 Zuclopenthixol (P) 42,5 g 0,03 g 0,0029
N05AF05 Zuclopenthixol (P) 2730 g 0,015 g 0,3749
N05AH Diazepines, oxazepines, thiazepines and oxepines 5,9685
N05AH02 Clozapine (O) 98186,75 g 0,3 g 0,6742
N05AH03 Olanzapine (O) 11638,9 g 0,01 g 2,3975
N05AH03 Olanzapine (P) 213,45 g 0,01 g 0,0440
N05AH04 Quetiapine (O) 553954,25 g 0,4 g 2,8528
N05AL Benzamides 0,1239
N05AL01 Sulpiride (O) 18312 g 0,8 g 0,0472
N05AL05 Amisulpride (O) 14910 g 0,4 g 0,0768
N05AN Lithium 0,3380
N05AN01 Lithium (O) 147660 g 0,9 g 0,3380
N05AX Other antipsychotics 1,7156
N05AX08 Risperidone (O) 1661,6 g 0,005 g 0,6846
N05AX08 Risperidone (P) 20,95 g 2,7 mg 0,0160
N05AX12 Aripiprazole (O) 6028,23 g 0,015 g 0,8279
N05AX12 Aripiprazole (P) 9,0675 g 0,015 g 0,0012
N05AX12 Aripiprazole (P) 663,6 g 0,0133 g 0,1028
N05AX13 Paliperidone (P) 96,825 g 2,5 mg 0,0798
N05AX15 Cariprazine (O) 4,998 g 3 mg 0,0034
N05B ANXIOLYTICS 12,9529
N05BA Benzodiazepine derivatives 12,9523
N05BA01 Diazepam (O) 27207,35 g 0,01 g 5,6046
N05BA01 Diazepam (P) 460,4 g 0,01 g 0,0948
N05BA01 Diazepam (R) 64,825 g 0,01 g 0,0134
N05BA06 Lorazepam (O) 1034,82 g 2,5 mg 0,8527
N05BA06 Lorazepam (P) 15,78 g 2,5 mg 0,0130
N05BA08 Bromazepam (O) 5379,42 g 0,01 g 1,1081
N05BA09 Clobazam (O) 368 g 0,02 g 0,0379
32/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N05BA12 Alprazolam (O) 2529,0875 g 0,001 g 5,2098
N05BA80 Phenazepam (O) 8,75 g 0,001 g 0,0180
N05BB Diphenylmethane derivatives <0,0001
N05BB01 Hydroxyzine (O) 0,4 g 0,075 g <0,0001
N05BE Azaspirodecanedione derivatives 0,0006
N05BE01 Buspirone (O) 9 g 0,03 g 0,0006
N05C HYPNOTICS AND SEDATIVES 22,6375
N05CD Benzodiazepine derivatives 0,2051
N05CD02 Nitrazepam (O) 222,3 g 0,005 g 0,0916
N05CD05 Triazolam (O) 0,015 g 0,25 mg 0,0001
N05CD08 Midazolam (O) 75,375 g 0,015 g 0,0104
N05CD08 Midazolam (P) 712,3 g 0,015 g 0,0978
N05CD08 Midazolam (P, R) 37,65 g 0,015 g 0,0052
N05CF Benzodiazepine related drugs 21,3026
N05CF01 Zopiclone (O) 60598,95 g 7,5 mg 16,6441
N05CF02 Zolpidem (O) 22234,52 g 0,01 g 4,5802
N05CF04 Eszopiclone (O) 76,104 g 2 mg 0,0784
N05CH Melatonin receptor agonists 0,6816
N05CH01 Melatonin (O) 661,81 g 2 mg 0,6816
N05CM Other hypnotics and sedatives 0,4481
N05CM09 Valerianae radix (O) 599130 pieces 3 pieces 0,4114
N05CM18 Dexmedetomidine (P) 17,8332 g 1 mg 0,0367
N06 PSYCHOANALEPTICS 46,5395
N06A ANTIDEPRESSANTS 40,7262
N06AA Non-selective monoamine reuptake inhibitors 1,9370
N06AA02 Imipramine (O) 45 g 0,1 g 0,0009
N06AA04 Clomipramine (O) 4425 g 0,1 g 0,0912
N06AA09 Amitriptyline (O) 56274,25 g 0,075 g 1,5456
N06AA10 Nortriptyline (O) 10897,5 g 0,075 g 0,2993
N06AB Selective serotonin reuptake inhibitors 24,0617
N06AB03 Fluoxetine (O) 39099,48 g 0,02 g 4,0271
N06AB04 Citalopram (O) 13565,14 g 0,02 g 1,3972
N06AB05 Paroxetine (O) 22728,6 g 0,02 g 2,3410
N06AB06 Sertraline (O) 173843,1 g 0,05 g 7,1621
N06AB08 Fluvoxamine (O) 980 g 0,1 g 0,0202
N06AB10 Escitalopram (O) 44244,28 g 0,01 g 9,1141
N06AF Monoamine oxidase inhibitors, non-selective 0,0115
N06AF04 Tranylcypromine (O) 56 g 0,01 g 0,0115
N06AG Monoamine oxidase type A inhibitors 0,0008
N06AG02 Moclobemide (O) 120 g 0,3 g 0,0008
N06AX Other antidepressants 14,7151
N06AX03 Mianserin (O) 50,4 g 0,06 g 0,0017
N06AX05 Trazodone (O) 21087 g 0,3 g 0,1448
N06AX11 Mirtazapine (O) 39220,65 g 0,03 g 2,6931
N06AX12 Bupropione (O) 159853,5 g 0,3 g 1,0976
N06AX14 Tianeptine (O) 25356,75 g 0,0375 g 1,3929
N06AX16 Venlafaxine (O) 212042,1 g 0,1 g 4,3679
N06AX17 Milnacipran (O) 8,4 g 0,1 g 0,0002
N06AX18 Reboxetine (O) 1,44 g 0,008 g 0,0004
N06AX21 Duloxetine (O) 82083,24 g 0,06 g 2,8181
N06AX22 Agomelatine (O) 14884,1 g 0,025 g 1,2264
N06AX26 Vortioxetine (O) 4718,42 g 10 mg 0,9720
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND
NOOTROPICS 2,1640
N06BA Centrally acting sympathomimetics 1,7780
N06BA04 Methylphenidate (O) 24284,16 g 0,03 g 1,6675
N06BA07 Modafinil (O) 864 g 0,3 g 0,0059
N06BA09 Atomoxetine (O) 4061,12 g 0,08 g 0,1046
N06BA12 Lisdexamfetamine dimesylate (O) 31,5 g
N06BC Xanthine derivatives
N06BC81 Caffeine citrate (O, P) 42 g
N06BX Other psychostimulants and nootropics 0,3860
33/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N06BX03 Piracetam (O) 433464 g 2,4 g 0,3720
N06BX18 Vinpocetine (O) 101,5 g 15 mg 0,0139
N06BX83 Aminobutyric acid (O) 33485 g
N06D ANTI-DEMENTIA DRUGS 3,6493
N06DA Anticholinesterases 1,1914
N06DA02 Donepezil (O) 4337,76 g 7,5 mg 1,1914
N06DX Other anti-dementia drugs 2,4579
N06DX01 Memantine (O) 5960,68 g 0,02 g 0,6139
N06DX02 Ginkgo folium (O) 107419,8 g 0,12 g 1,8440
N06DX80 cerebrolysine (P) 360,46 g
N07 OTHER NERVOUS SYSTEM DRUGS 12,1568
N07A PARASYMPATHOMIMETICS 0,3566
N07AA Anticholinesterases 0,3566
N07AA01 neostigmine (P) 26,75 g 0,002 g 0,0276
N07AA02 Pyridostigmine bromide (O) 26892 g 0,18 g 0,3078
N07AA80 Neostigmine+Glycopyrronium (P) 10350 ml 1 ml 0,0213
N07AX Other parasympathomimetics
N07AX01 Pilocarpine (O) 1,26 g
N07B DRUGS USED IN ADDICTIVE DISORDERS 3,3302
N07BA Drugs used in nicotine dependence 1,7231
N07BA01 Nicotine (O) 16377,04 g 0,03 g 1,1245
N07BA01 Nicotine (TD) 3898,874 g 0,014 g 0,5737
N07BA03 Varenicline (O) 24,154 g 2 mg 0,0249
N07BB Drugs used in alcohol dependence 0,4209
N07BB01 Disulfiram (O) 33820 g 0,2 g 0,3483
N07BB01 Disulfiram (P) 80 g
N07BB03 Acamprosate (O) 347,652 g 2 g 0,0004
N07BB04 Naltrexone (O) 1598,8 g 50 mg 0,0659
N07BB05 nalmefene (O) 55,188 g 18 mg 0,0063
N07BC Drugs used in opioid dependence 1,1862
N07BC02 Methadone (O) 13848 g 0,025 g 1,1410
N07BC51 Buprenorphine+Naloxone (SL) 175,504 g 8 mg 0,0452
N07C ANTIVERTIGO PREPARATIONS 8,4395
N07CA Antivertigo preparations 8,4395
N07CA01 Betahistine (O) 84223,92 g 0,024 g 7,2290
N07CA02 Cinnarizine (O) 49865 g 0,09 g 1,1413
N07CA03 Flunarizine (O) 3,3 g 0,01 g 0,0007
N07CA80 Cinnarizine+Dimenhydrinate (O) 2990 g 90 mg 0,0684
N07X OTHER NERVOUS SYSTEM DRUGS 0,0305
N07XX Other nervous system drugs 0,0305
N07XX02 Riluzole (O) 1310,4 g 0,1 g 0,0270
N07XX06 Tetrabenazine (O) 120,4 g 0,1 g 0,0025
N07XX07 Fampridine (O) 10,08 g 20 mg 0,0010
N07XX14 Edaravone (P) 4,5 g
P ANTIPARASITIC PRODUCTS, INSECTICIDES AND
REPELLENTS 1,0909
P01 ANTIPROTOZOALS 0,8872
P01A AGENTS AGAINST AMOEBIASIS AND OTHER
PROTOZOAL DISEASES 0,1744
P01AB Nitroimidazole derivatives 0,1744
P01AB01 Metronidazole (O) 169330 g 2 g 0,1744
P01AB01 Metronidazole (O, V) 831 g
P01B ANTIMALARIALS 0,7128
P01BA Aminoquinolines 0,6861
P01BA02 Hydroxychloroquine (O) 171702 g 0,516 g 0,6855
P01BA03 Primaquine (O) 4,5 g 0,015 g 0,0006
P01BB Biguanides 0,0264
P01BB51 Proguanil+Atovaquone (O) 792 pieces 16 pieces 0,0001
P01BB51 Proguanil+Atovaquone (O) 51048 pieces 4 pieces 0,0263
P01BC Methanolquinolines 0,0001
P01BC01 Quinine (P) 60 g 1,5 g 0,0001
P01BD Diaminopyrimidines 0,0003
34/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
P01BD01 Pyrimethamine (O) 9,75 g 0,075 g 0,0003
P02 ANTHELMINTICS 0,2037
P02B ANTITREMATODALS 0,0001
P02BA Quinoline derivatives and related substances 0,0001
P02BA01 Praziquantel (O) 198 g 3 g 0,0001
P02C ANTINEMATODAL AGENTS 0,2036
P02CA Benzimidazole derivatives 0,2029
P02CA01 Mebendazole (O) 17140,6 g 0,2 g 0,1765
P02CA03 Albendazole (O) 5112 g 0,4 g 0,0263
P02CF Avermectines 0,0007
P02CF01 Ivermectin (O) 4,14 g 12 mg 0,0007
P03 ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES
AND REPELLENTS
P03A ECTOPARASITICIDES, INCL. SCABICIDES
P03AC Pyrethrines, incl. synthetic compounds
P03AC04 Permethrin (C) 160090 g
P03AX Other ectoparasiticides, incl. scabicides
P03AX01 Benzyl benzoate (C) 284790 g
R RESPIRATORY SYSTEM 96,3499
R01 NASAL PREPARATIONS 39,0823
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS
FOR TOPICAL USE 36,7791
R01AA Sympathomimetics, plain 23,3489
R01AA05 Oxymetazoline (N) 265,2525 g 0,4 mg 1,3660
R01AA07 Xylometazoline (N) 8537,2875 g 0,8 mg 21,9829
R01AB Sympathomimetics, combinations excl. corticosteroids 3,6750
R01AB83 Xylometazoline+Ipratropium bromide (N) 223180 ml 0,8 ml 0,5747
R01AB85 Xylometazoline+Dexpanthenol (N) 1204030 ml 0,8 ml 3,1003
R01AC Antiallergic agents, excl. corticosteroids 0,3890
R01AC03 Azelastine (N) 105,76 g 0,56 mg 0,3890
R01AD Corticosteroids 9,3661
R01AD01 Beclometasone (N) 5,21 g 0,4 mg 0,0268
R01AD05 Budesonide (N) 34,2561 g 0,2 mg 0,3528
R01AD08 Fluticasone (N) 89,718 g 0,2 mg 0,9241
R01AD09 Mometasone (N) 407,652 g 0,2 mg 4,1987
R01AD12 Fluticasone furoate (N) 177,1605 g 0,11 mg 3,3176
R01AD81 Fluticasone+Azelastine (N) 1060320 doses 4 doses 0,5461
R01AX Other nasal preparations
R01AX06 Mupirocin (N) 24 g
R01AX83 Retinol+Tocopherol (N) 146040 ml
R01B NASAL DECONGESTANTS FOR SYSTEMIC USE 2,3033
R01BA Sympathomimetics 2,3033
R01BA02 Pseudoephedrine (O) 156945,12 g 0,24 g 1,3471
R01BA81 Pseudoephedrine+Triprolidine (O) 29880,12 g 0,24 g 0,2565
R01BA84 Pseudoephedrine+Guaifenesin (O) 9267,6 g 0,24 g 0,0795
R01BA89 Pseudoephedrine+Loratadine (O) 11276,16 g 0,24 g 0,0968
R01BA93 Pseudoephedrine+Cetirizine (O) 60980,64 g 0,24 g 0,5234
R02 THROAT PREPARATIONS 2,6112
R02A THROAT PREPARATIONS 2,6112
R02AA Antiseptics 2,1806
R02AA06 Cetylpyridinium chloride (O) 1386 pieces
R02AA82 Benzydamine+Cetylpyridinium chloride (O) 818940 ml
R02AA82 Benzydamine+Cetylpyridinium chloride (O) 2041936 pieces 6 pieces 0,7010
R02AA89 Povidone, iodinated+Allantoin (O) 328650 ml
R02AA92 Dequalinium+Cinchocaine (O) 1075380 pieces 6 pieces 0,3692
R02AA94 Amylmetacresol+Dichlorobenzyl alcohol (O) 1252416 pieces 6 pieces 0,4300
R02AA95 Amylmetacresol+Dichlorobenzyl alcohol+Levomenthol (O) 1153632 pieces 6 pieces 0,3961
R02AA96 Amylmetacresol+Dichlorobenzyl alcohol+Ascorbic acid (O) 828120 pieces 6 pieces 0,2843
R02AA98 Cetylpyridinium chloride+Benzocaine (O) 18 pieces 6 pieces <0,0001
R02AD Anesthetics, local 0,0227
R02AD80 Lidocaine+Propyl parahydroxybenzoate (O) 65980 pieces 6 pieces 0,0227
R02AX Other throat preparations 0,4080
35/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R02AX01 Flurbiprofen (O) 8713,74 g 44 mg 0,4080
R02AX80 Thyme herb+Sage leaf (O) 23880 ml
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES 27,5760
R03A ADRENERGICS, INHALANTS 20,0939
R03AC Selective beta-2-adrenoceptor agonists 3,5904
R03AC02 Salbutamol (I) 935,452 g 0,8 mg 2,4087
R03AC02 Salbutamol (I) 1367,6 g 0,01 g 0,2817
R03AC04 Fenoterol (I) 56,8 g 0,6 mg 0,1950
R03AC12 Salmeterol (I) 3,717 g 0,1 mg 0,0766
R03AC13 Formoterol (I) 4,3448 g 0,024 mg 0,3729
R03AC18 Indacaterol (I) 18,5985 g 0,15 mg 0,2554
R03AK Adrenergics in combination with corticosteroids or other drugs,
excl. anticholinergics 12,5187
R03AK06 Salmeterol+Fluticasone (I) 518280 doses 4 doses 0,2669
R03AK06 Salmeterol+Fluticasone (I) 2082420 doses 2 doses 2,1448
R03AK07 Formoterol+Budesonide (I) 1066080 doses 2 doses 1,0980
R03AK07 Formoterol+Budesonide (I) 6442020 doses 4 doses 3,3176
R03AK08 Formoterol+Beclometasone (I) 3817980 doses 4 doses 1,9662
R03AK10 Vilanterol+Fluticasone furoate (I) 1758090 doses 1 doses 3,6216
R03AK13 Salbutamol+Beclometasone (I) 201200 doses 4 doses 0,1036
R03AL Adrenergics in combinations with anticholinergics incl. triple
combinations with corticosteroids 3,9848
R03AL01 Fenoterol+Ipratropium bromide (I) 221780 ml 16 ml 0,0286
R03AL01 Fenoterol+Ipratropium bromide (I) 2585200 doses 6 doses 0,8876
R03AL03 Vilanterol+Umeclidinium (I) 402690 doses 1 doses 0,8295
R03AL04 Indacaterol+Glycopyrronium (I) 160260 doses 1 doses 0,3301
R03AL05 Formoterol+Aclidinium (I) 366540 doses 2 doses 0,3775
R03AL06 Olodaterol+Tiotropium (I) 646380 doses 2 doses 0,6658
R03AL07 Formoterol+Glycopyrronium (I) 279960 doses 4 doses 0,1442
R03AL08 Vilanterol+Umeclidinium+Fluticasone furoate (I) 103800 doses 1 doses 0,2138
R03AL09 Formoterol+Glycopyrronium+Beclometasone (I) 912720 doses 4 doses 0,4700
R03AL11 Formoterol+Glycopyrronium+Budesonide (I) 73320 doses 4 doses 0,0378
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES,
INHALANTS 4,6161
R03BA Glucocorticoids 1,5513
R03BA01 Beclometasone (I) 0,1 g 1,5 mg 0,0001
R03BA02 Budesonide (I) 210,3 g 1,5 mg 0,2888
R03BA02 Budesonide (I) 278,972 g 0,8 mg 0,7183
R03BA05 Fluticasone (I) 158,457 g 0,6 mg 0,5440
R03BB Anticholinergics 3,0648
R03BB01 Ipratropium bromide (I) 19,66 g 0,12 mg 0,3375
R03BB01 Ipratropium bromide (I) 33,105 g 0,3 mg 0,2273
R03BB04 Tiotropium (I) 3,2122 g 0,005 mg 1,3234
R03BB05 Aclidinium (I) 126,5074 g 0,644 mg 0,4047
R03BB06 Glycopyrronium (I) 7,2362 g 44 mcg 0,3388
R03BB07 Umeclidinium (I) 11,5649 g 55 mcg 0,4331
R03C ADRENERGICS FOR SYSTEMIC USE 0,0980
R03CC Selective beta-2-adrenoceptor agonists 0,0980
R03CC02 Salbutamol (O) 570,96 g 0,012 g 0,0980
R03CC02 Salbutamol (P) 0,095 g 0,012 g <0,0001
R03D OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY
DISEASES 2,7680
R03DA Xanthines 1,0798
R03DA04 Theophylline (O) 206480 g 0,4 g 1,0633
R03DA05 Aminophylline (P) 4796,7 g 0,6 g 0,0165
R03DC Leukotriene receptor antagonists 1,5992
R03DC03 Montelukast (O) 7763,308 g 0,01 g 1,5992
R03DX Other systemic drugs for obstructive airway diseases 0,0890
R03DX05 Omalizumab (P) 209,7 g 0,016 g 0,0270
R03DX07 Roflumilast (O) 0,095 g 0,5 mg 0,0004
R03DX09 Mepolizumab (P) 68 g 3,6 mg 0,0389
R03DX10 Benralizumab (P) 5,94 g 0,54 mg 0,0227
36/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R05 COUGH AND COLD PREPARATIONS 7,4035
R05C EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH
SUPPRESSANTS 7,2390
R05CA Expectorants 0,0077
R05CA03 Guaifenesin (O) 3360 g 0,9 g 0,0077
R05CA12 Hederae helicis folium (O) 166632 pieces
R05CA12 Hederae helicis folium (O) 7406965 ml
R05CA86 Iceland moss (O) 6530550 ml
R05CA87 Distillate of rectified essential oils of eucalyptus, sweet orange,
myrtle and lemon (O) 2019220 pieces
R05CA88 Thyme herb+Wild thyme+Plantain (O) 525900 ml
R05CA89 Thyme herb+Hederae helicis folium (O) 387600 ml
R05CA91 Thyme herb+Marshmallow root (O) 210420 pieces
R05CA91 Thyme herb+Marshmallow root (O) 4960050 ml
R05CA92 Thyme herb (O) 138520 pieces
R05CB Mucolytics 7,2313
R05CB01 Acetylcysteine (I, P) 1077 g
R05CB01 Acetylcysteine (O) 1107653,2 g 0,5 g 4,5634
R05CB01 Acetylcysteine (P) 5892 g
R05CB02 Bromhexine (O) 6919,84 g 0,024 g 0,5939
R05CB03 Carbocisteine (O) 176156,25 g 1,5 g 0,2419
R05CB06 Ambroxol (O) 105584,85 g 0,12 g 1,8125
R05CB13 Dornase alfa (I) 23,715 g 2,5 mg 0,0195
R05D COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH
EXPECTORANTS 0,0901
R05DB Other cough suppressants 0,0901
R05DB09 Oxeladin (O) 3498,25 g 0,08 g 0,0901
R05F COUGH SUPPRESSANTS AND EXPECTORANTS,
COMBINATIONS 0,0744
R05FA Opium derivatives and expectorants 0,0744
R05FA80 Codeine+Guaifenesin (O) 1083750 ml 30 ml 0,0744
R05X OTHER COLDPREPARATIONS
R05XA Other cold combination preparations
R05XA80 Gentian root+Primula flower+Common sorrel+Elder
flower+Verbena herb (O) 1700780 pieces
R05XA80 Gentian root+Primula flower+Common sorrel+Elder
flower+Verbena herb (O) 2129200 ml
R05XA82 Ibuprofen+Pseudoephedrine (O) 5508 g
R06 ANTIHISTAMINES FOR SYSTEMIC USE 19,6762
R06A ANTIHISTAMINES FOR SYSTEMIC USE 19,6762
R06AA Aminoalkyl ethers 0,4448
R06AA02 Diphenhydramine (O) 10 g 0,2 g 0,0001
R06AA02 Diphenhydramine (P) 12 g
R06AA04 Clemastine (O) 387,38 g 0,002 g 0,3990
R06AA04 Clemastine (P) 44,34 g 0,002 g 0,0457
R06AD Phenothiazine derivatives 0,0002
R06AD02 Promethazine (O) 2 g 0,025 g 0,0002
R06AE Piperazine derivatives 9,8576
R06AE07 Cetirizine (O) 45436,995 g 0,01 g 9,3598
R06AE09 Levocetirizine (O) 1208,33 g 0,005 g 0,4978
R06AX Other antihistamines for systemic use 9,3737
R06AX13 Loratadine (O) 19838,1 g 0,01 g 4,0865
R06AX15 Mebhydrolin (O) 29 g 0,2 g 0,0003
R06AX17 Ketotifen (O) 3,69 g 0,002 g 0,0038
R06AX22 Ebastine (O) 7135 g 0,01 g 1,4698
R06AX27 Desloratadine (O) 2682,32 g 0,005 g 1,1051
R06AX28 Rupatadine (O) 890,48 g 0,01 g 0,1834
R06AX29 Bilastine (O) 24513,2 g 20 mg 2,5248
R07 OTHER RESPIRATORY SYSTEM PRODUCTS 0,0006
R07A OTHER RESPIRATORY SYSTEM PRODUCTS 0,0006
R07AA Lung surfactants 0,0005
R07AA81 Porcine lung phospholipids (endotrach) 39,84 g 0,16 g 0,0005
37/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R07AX Other respiratory system products 0,0001
R07AX02 ivacaftor (O) 16,8 g 0,3 g 0,0001
R07AX32 Ivacaftor+Tezacaftor+Elexacaftor (O) 42 g
S SENSORY ORGANS 36,0108
S01 OPHTHALMOLOGICALS 36,0108
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA01 Chloramphenicol (S) 138030 ml
S01AA12 Tobramycin (S) 30315 ml
S01AA12 Tobramycin (S) 51618 g
S01AA13 Fusidic acid (S) 32070 g
S01AD Antivirals
S01AD03 Aciclovir (S) 3514,5 g
S01AE Fluoroquinolones
S01AE03 Ciprofloxacin (S) 8,07 g
S01AE03 Ciprofloxacin (S) 10885 ml
S01AE05 Levofloxacin (S) 32000 ml
S01AE07 Moxifloxacin (S) 13950 ml
S01AX Other antiinfectives
S01AX18 Povidone, iodinated (S) 280 ml
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA01 Dexamethasone (S) 220 pieces
S01BA01 Dexamethasone (S) 16254,7 g
S01BA01 Dexamethasone (S) 148315 ml
S01BA02 Hydrocortisone (S) 3978 g
S01BA09 Clobetasone (S) 30820 ml
S01BA14 Loteprednol (S) 9785 ml
S01BC Antiinflammatory agents, non-steroids
S01BC03 Diclofenac (S) 15 ml
S01BC05 Ketorolac (S) 5000 ml
S01BC10 Nepafenac (S) 21955 ml
S01BC11 Bromfenac (S) 12375 ml
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN
COMBINATION
S01CA Corticosteroids and antiinfectives in combination
S01CA80 Dexamethasone+Neomycin+Polymyxin B (S) 49635 ml
S01CA81 Dexamethasone+Tobramycin (S) 16030 g
S01CA81 Dexamethasone+Tobramycin (S) 41225 ml
S01CA82 Dexamethasone+Chloramphenicol (S) 51642,5 g
S01CA82 Dexamethasone+Chloramphenicol (S) 447920 ml
S01CA84 Dexamethasone+Levofloxacin (S) 865 ml
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS 36,0108
S01EA Sympathomimetics in glaucoma therapy 0,0261
S01EA05 Brimonidine (S) 2530 ml 0,2 ml 0,0261
S01EB Parasympathomimetics 0,0177
S01EB01 Pilocarpine (S) 2670 ml 0,4 ml 0,0138
S01EB02 Carbachol (S) 768 ml 0,4 ml 0,0040
S01EB09 Acetylcholine chloride (S) 0,2 g
S01EC Carbonic anhydrase inhibitors 3,7834
S01EC01 Acetazolamide (O) 25870 g 0,75 g 0,0711
S01EC01 Acetazolamide (P) 25 g 0,75 g 0,0001
S01EC03 Dorzolamide (S) 154225 ml 0,3 ml 1,0590
S01EC04 Brinzolamide (S) 152685 ml 0,2 ml 1,5726
S01EC80 Brinzolamide+Brimonidine (S) 104925 ml 0,2 ml 1,0807
S01ED Beta blocking agents 24,3791
S01ED01 Timolol (S) 24270 ml 0,2 ml 0,2500
S01ED01 Timolol (S) 245445 g 40 mg 12,6401
S01ED02 Betaxolol (S) 76575 ml 0,2 ml 0,7887
S01ED80 Timolol+Dorzolamide (S) 301550 ml 0,2 ml 3,1059
S01ED81 Timolol+Travoprost (S) 39262,5 ml 0,2 ml 0,4044
S01ED82 Timolol+Bimatoprost (S) 107109 ml 0,2 ml 1,1032
38/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
S01ED83 Timolol+Brinzolamide (S) 227515 ml 0,2 ml 2,3433
S01ED84 Timolol+Latanoprost (S) 73820 ml 0,2 ml 0,7603
S01ED85 Timolol+Tafluprost (S) 289638 ml 0,2 ml 2,9832
S01EE Prostaglandin analogues 7,8045
S01EE01 Latanoprost (S) 263740 ml 0,1 ml 5,4329
S01EE03 Bimatoprost (S) 261 ml 0,1 ml 0,0054
S01EE04 Travoprost (S) 56862,5 ml 0,1 ml 1,1713
S01EE05 Tafluprost (S) 174024 ml 0,3 ml 1,1949
S01F MYDRIATICS AND CYCLOPLEGICS
S01FA Anticholinergics
S01FA01 Atropine (S) 615 ml
S01FA04 Cyclopentolate (S) 30800 ml
S01FA06 Tropicamide (S) 16630 ml
S01FA80 Tropicamide+Phenylephrine+Lidocaine (int.cam) 1480 pieces
S01FB Sympathomimetics excl. antiglaucoma preparations
S01FB01 Phenylephrine (S) 7735 ml
S01G DECONGESTANTS AND ANTIALLERGICS
S01GA Sympathomimetics used as decongestants
S01GA02 Tetryzoline (S) 276225 ml
S01GX Other antiallergics
S01GX01 Cromoglicic acid (S) 110210 ml
S01GX07 Azelastine (S) 49782 ml
S01GX09 Olopatadine (S) 49955 ml
S01H LOCAL ANESTHETICS
S01HA Local anesthetics
S01HA03 Tetracaine (S) 24780 ml
S01HA04 Proxymetacaine (S) 37875 ml
S01J DIAGNOSTIC AGENTS
S01JA Colouring agents
S01JA01 Fluorescein (P) 362 g
S01JA01 Fluorescein (P) 2820 ml
S01JA81 Fluorescein+Oxybuprocaine+Chlorobutanol (S) 2525 ml
S01K SURGICAL AIDS
S01KA Viscoelastic substances
S01KA02 Hypromellose (S) 5940 ml
S01L OCULAR VASCULAR DISORDER AGENTS
S01LA Antineovascularisation agents
S01LA01 Verteporfin (P) 3 pieces
S01LA05 aflibercept (S) 205 pieces
S01LA06 Brolucizumab (S) 0,516 g
S01X OTHER OPHTHALMOLOGICALS
S01XA Other ophthalmologicals
S01XA03 Sodium chloride (S) 1151,5 g
S01XA18 Ciclosporin (S) 14535 ml
S01XA80 Retinol+Dexpanthenol (S) 6041 g
S01XA81 Carbomer (S) 188900 g
S01XA82 Hypromellose (S) 223620 ml
S01XA85 Hypromellose+Dextran (S) 410355 ml
S01XA86 cytochrome C+Adenosine+Nicotinamide (S) 90 ml
S02 OTOLOGICALS
S02C CORTICOSTEROIDS AND ANTIINFECTIVES IN
COMBINATION
S02CA Corticosteroids and antiinfectives in combination
S02CA81 Dexamethasone+Neomycin+Acetic acid, glacial (A) 4210 ml
S02CA82 Hydrocortisone+Ciprofloxacin (A) 143170 ml
S02D OTHER OTOLOGICALS
S02DA Analgesics and anesthetics
S02DA81 Phenazone+Lidocaine (A) 1875 ml
T HERBAL MEDICINAL PRODUCTS
T01 HERBAL MEDICINAL PRODUCTS
T01R HERBAL MEDICINAL PRODUCTS
T01RS Herbal medicinal products
39/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
T01RS01 herbal preparation (O) 505900 pieces
T01RS01 herbal preparation (O) 8862890 ml
T01RS02 homeopathic preparations (A) 5420 ml
T01RS02 homeopathic preparations (C) 617000 g
T01RS02 homeopathic preparations (O) 1940 g
T01RS02 homeopathic preparations (O) 1326010 pieces
T01RS02 homeopathic preparations (O) 1683700 ml
V VARIOUS 0,2127
V01 ALLERGENS
V01A ALLERGENS
V01AA Allergen extracts
V01AA02 Grass pollen (O) 226 pieces
V01AA02 Grass pollen (P) 225 pieces
V01AA03 House dust mites (O) 253 pieces
V01AA03 House dust mites (P) 30 ml
V01AA03 House dust mites (P) 268 pieces
V01AA05 Tree pollen (P) 482 pieces
V01AA05 Tree pollen (SL) 463 pieces
V01AA07 Allergen products (insects) (P) 330 pieces
V01AA11 Animals (O) 34 pieces
V01AA80 Tree and grass pollen (O) 159 pieces
V01AA80 Tree and grass pollen (P) 40 pieces
V01AA83 Grass pollen+Flowers (O) 18 pieces
V01AA84 Tree and flower pollen (O) 18 pieces
V03 ALL OTHER THERAPEUTIC PRODUCTS 0,2127
V03A ALL OTHER THERAPEUTIC PRODUCTS 0,2127
V03AB Antidotes
V03AB04 Pralidoxime (O, P) 120 g
V03AB06 Sodium thiosulphate (P) 1200 g
V03AB09 Dimercaprol (P) 4,8 g
V03AB14 Protamine sulfate (P) 214,5 g
V03AB15 Naloxone (N) 3,6 g
V03AB15 Naloxone (P) 1,172 g
V03AB16 Ethanol (P) 23400 ml
V03AB17 Methylthioninium chloride (P) 193,6 g
V03AB19 Physostigmine (P) 0,15 g
V03AB21 Potassium iodide (O) 78 g
V03AB25 Flumazenil (P) 0,3 g
V03AB32 Glutathione (P) 630 g
V03AB33 Hydroxocobalamin (P) 110 g
V03AB34 Fomepizole (P) 20,5 g
V03AB35 Sugammadex (P) 102 g
V03AB37 Idarucizumab (P) 115 g
V03AB81 Obidoxime chloride+Atropine (P) 100 pieces
V03AC Iron chelating agents
V03AC01 Deferoxamine (P) 60 g
V03AC02 Deferiprone (O) 900 g
V03AC03 Deferasirox (O) 6285,6 g
V03AE Drugs for treatment of hyperkalemia and hyperphosphatemia 0,1558
V03AE01 Polystyrene sulfonate (O, R) 1774155,5 g 45 g 0,0812
V03AE02 Sevelamer (O) 185904 g 6,4 g 0,0598
V03AE03 Lanthan (O) 16132,5 g 2,25 g 0,0148
V03AF Detoxifying agents for antineoplastic treatment 0,0569
V03AF01 Mesna (P) 5268 g
V03AF03 Calcium folinate (O) 38,25 g 0,06 g 0,0013
V03AF07 Rasburicase (P) 0,585 g 0,014 g 0,0001
V03AF09 Glucarpidase (P) 8000 U
V03AF10 Sodium levofolinate (P) 808,5 g 0,03 g 0,0555
V03AH Drugs for treatment of hypoglycemia
V03AH01 Diazoxide (O) 10 g
V03AN Medical gases
V03AN01 Oxygen (I) 756792000 ml
40/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
V03AN05 Air, medicinal (I) 4830000 ml
V04 DIAGNOSTIC AGENTS
V04C OTHER DIAGNOSTIC AGENTS
V04CD Tests for pituitary function
V04CD04 Corticorelin (P) 0,0014 g
V04CF Tuberculosis diagnostics
V04CF01 Tuberculin (P) 4800 U
V04CJ Tests for thyreoidea function
V04CJ02 Protirelin (P) 0,001 g
V04CX Other diagnostic agents
V04CX01 Indocyanine green (P) 8,4 g
V04CX03 Methacholine (I) 37,53 g
V04CX04 Mannitol (I) 72,39 g
V04CX06 Hexaminolevulinate (P) 20,06 g
V04CX87 Carbon monoxide+Helium (I) 20000 ml
V07 ALL OTHER NON-THERAPEUTIC PRODUCTS
V07A ALL OTHER NON-THERAPEUTIC PRODUCTS
V07AB Solvents and diluting agents, incl. irrigating solutions
V07AB80 Sodium chloride (P) 9680052 ml
V07AB83 Water for injection (NA) 38910000 ml
V07AB83 Water for injection (P) 2400000 ml
V08 CONTRAST MEDIA
V08A X-RAY CONTRAST MEDIA, IODINATED
V08AA Watersoluble, nephrotropic, high osmolar X-ray contrast media
V08AA01 Sodium amidotrizoate+Meglumine Amidotrizoate (P) 4000 ml
V08AB Watersoluble, nephrotropic, low osmolar X-ray contrast media
V08AB02 Iohexol (P) 1907365,5 g
V08AB05 Iopromide (P) 1133405 g
V08AB09 Iodixanol (P) 2838794 g
V08AD Non-watersoluble X-ray contrast media
V08AD01 Ethyl esters of iodised fatty acids (P) 72 g
V08B X-RAY CONTRAST MEDIA, NON-IODINATED
V08BA Barium sulfate containing X-ray contrast media
V08BA01 Barium sulfate (O) 134091,92 g
V08C MAGNETIC RESONANCE IMAGING CONTRAST MEDIA
V08CA Paramagnetic contrast media
V08CA01 Gadopentetic acid (P) 3120 ml
V08CA02 Gadoteric acid (P) 61550 ml
V08CA09 Gadobutrol (P) 90085 ml
V08CA10 Gadoxetic acid (P) 5800 ml
V08D ULTRASOUND CONTRAST MEDIA
V08DA Ultrasound contrast media
V08DA05 Sulfur hexafluoride, phospholipid microspheres (P) 150 ml
V09 DIAGNOSTIC RADIOPHARMACEUTICALS
V09A CENTRAL NERVOUS SYSTEM
V09AB Iodine (123I) compounds
V09AB03 Ioflupane (123I) (P) 480 ml
V09F THYROID
V09FX Various thyroid diagnostic radiopharmaceuticals
V09FX01 Technetium (99mTc) pertechnetate (S) 80 pieces
V10 THERAPEUTIC RADIOPHARMACEUTICALS
V10X OTHER THERAPEUTIC RADIOPHARMACEUTICALS
V10XA Iodine (131I) compounds
V10XA01 Sodium iodide (131I) (O) 86 pieces
41/41
Dear Sophie,
Thank you for the feedback.
Please find attached the files for 2019-2022, but please be informed that these are compiled using the ATC codes that were valid at that time.
We can provide this data to you also in one dataset and using the currently valid ATC codes (2025). 2024 data will be available by the end of February.
Kind regards,
Janne Sepp
State Agency of Medicines
Department of Post-Authorisation Safety
Bureau of Drug Statistics
Specialist
Phone: +372 737 4140
Nooruse 1, 50411 Tartu, Estonia
This e-mail and any attachments transmitted may contain confidential and privileged information. If you are not the intended recipient, please notify the sender immediately by returning the e-mail and permanently deleting what you have recieved. Any dissemination or use of this information by a third person without permission is prohibited and may be illegaal.
Saatja: [email protected] <[email protected]>
Saatmisaeg: esmaspäev, 6. jaanuar 2025 13:24
Adressaat: Janne Sepp <[email protected]>
Teema: RE: OECD Health Statistic Inquiry
Tähelepanu! Tegemist on väljastpoolt asutust saabunud kirjaga. Tundmatu saatja korral palume linke ja faile mitte avada. |
Hi Janne,
Hope you had a wonderful holiday season!
Many thanks for your guidance on this matter, it is very helpful.
I was wondering if it would be possible to receive similar reports to “DDD 2023 ENG.pdf” for previous years so we are able to create a time series?
I wish you a wonderful start to the new year!
Best,
Sophie
Restricted Use - À usage restreint
From: Janne Sepp <[email protected]>
Sent: Monday, December 9, 2024 9:54 AM
To: WANG Sophie, ELS/HD <[email protected]>
Subject: Vs: OECD Health Statistic Inquiry
Dear Sophie,
Thank you for your e-mail and apologizes for the delay in answering.
In Estonia the consumption of ATC N01 group (anesthetics) is collected at the national level (wholesale data).
You can find a more detailed information on our website: https://ravimiamet.ee/en/statistics/statistics-medicines
On the same page there is a data table (named “DDD 2023 ENG.pdf”) on active substance level, covering also N01 units: https://ravimiamet.ee/sites/default/files/documents/2024-04/DDD%202023%20ENG.pdf
Kind regards,
Janne Sepp
State Agency of Medicines
Department of Post-Authorisation Safety
Bureau of Drug Statistics
Specialist
Phone: +372 737 4140
Nooruse 1, 50411 Tartu, Estonia
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From: [email protected] <[email protected]>
Sent: esmaspäev, 25. november 2024 10:59
To: Ravimiamet <[email protected]>
Subject: OECD Health Statistic Inquiry
Tähelepanu! Tegemist on väljastpoolt asutust saabunud kirjaga. Tundmatu saatja korral palume linke ja faile mitte avada. |
Hello,
Pleased to e-meet you. I am from OECD Health working on climate and health issues. I am quite interested in the database of medicine statistics provided here: PxWeb - Select table. We are currently in the process of looking at anesthetic gas volumes consumed in countries and wanted to inquire about whether if consumption of ATC N01 group (anesthetics) is collected at the national level? And if so, at what unit is this data collected?
Many thanks,
Sophie
Sophie Wang, PhD
Health Policy Researcher, Health Division
Directorate for Employment, Labour, and Social Affairs
2, rue André Pascal – 75775 Paris Cedex 16
[email protected] | Tel: +33 1 85 55 49 44
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Restricted Use - À usage restreint
This communication is intended only for the use of the individual or entity to whom it is addressed and others authorised by the sender to receive it. Any unauthorised disclosure, use, or publication of this information is not allowed. If you have received this communication in error, please notify the sender immediately and delete it from your system.
Cette communication est uniquement destinée à la personne ou à l’entité à laquelle elle est adressée et à d’autres autorisées par l’émetteur à la recevoir. Aucune divulgation, utilisation ou publication de ces informations n’est autorisée. Si vous avez reçu cette communication par erreur, veuillez en notifier l’émetteur immédiatement et la détruire de votre système.
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day A ALIMENTARY TRACT AND METABOLISM 176,5588 A01 STOMATOLOGICAL PREPARATIONS 0,0742 A01A STOMATOLOGICAL PREPARATIONS 0,0742 A01AB Antiinfectives and antiseptics for local oral treatment 0,0742 A01AB09 Miconazole(O) 7174,4 g 0,2 g 0,0742 A01AB12 Hexetidine(O) 1154880 ml A01AB81 Neomycin+Benzocaine(dental) 14050 pieces A01AB82 Demeclocycline+Triamcinolone(dental) 780 g A01AD Other agents for local oral treatment A01AD80 Lidocaine+Cetylpyridinium chloride(gingival) 154380 g A01AD81 Lidocaine+Cetrimide(O) 53485 g A01AD82 Choline salicylate(O) 645600 pieces A01AD83 Lidocaine+Chamomille extract(O) 391340 g A01AD90 Lidocaine+Paraformaldehyde(dental) 444 g A02 DRUGS FOR ACID RELATED DISORDERS 56,2174 A02A ANTACIDS 1,1870
A02AD Combinations and complexes of aluminium, calcium and magnesium compounds
1,1870
A02AD81 Aluminium hydroxide+Magnesium hydroxide(O) 851440 pieces 10 pieces 0,1761 A02AD81 Aluminium hydroxide+Magnesium hydroxide(O) 3907014 ml 50 ml 0,1616 A02AD83 Calcium carbonate+Magnesium carbonate(O) 4107672 pieces 10 pieces 0,8494
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
55,0304
A02BA H2-receptor antagonists 1,3430 A02BA02 Ranitidine(O) 192291,75 g 0,3 g 1,3254 A02BA02 Ranitidine(P) 2568 g 0,3 g 0,0177 A02BC Proton pump inhibitors 53,6743 A02BC01 Omeprazole(O) 283739,28 g 0,02 g 29,3346 A02BC02 Pantoprazole(O) 258796,44 g 0,04 g 13,3779 A02BC02 Pantoprazole(P) 461,6 g 0,04 g 0,0239 A02BC03 Lansoprazole(O) 4,2 g 0,03 g 0,0003 A02BC05 Esomeprazole(O) 155634,92 g 0,03 g 10,7270 A02BC05 Esomeprazole(P) 3055,6 g 0,03 g 0,2106 A02BC08 Vonoprazan(O) 4 g A02BD Combinations for eradication of Helicobacter pylori 0,0011 A02BD08 Bismuth subcitrate+Tetracycline+Metronidazole (O) 6240 pieces 12 pieces 0,0011
A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
0,0120
A02BX02 Sucralfate(O) 22800 g 4 g 0,0118 A02BX03 Pirenzepine(O) 10 g 0,1 g 0,0002 A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS 8,2131
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS 7,2698
A03AA Synthetic anticholinergics, esters with tertiary amino group 1,0663 A03AA04 Mebeverine(O) 154704 g 0,3 g 1,0663 A03AB Synthetic anticholinergics, quaternary ammonium compounds 0,0003 A03AB02 Glycopyrronium(P) 0,046 g 0,3 mg 0,0003 A03AD Papaverine and derivatives 4,5268 A03AD01 Papaverine hydrochloride(P) 66,8 g 0,1 g 0,0014 A03AD02 Drotaverine(O) 215250,88 g 0,1 g 4,4508 A03AD02 Drotaverine(P) 3608 g 0,1 g 0,0746 A03AX Other drugs for functional gastrointestinal disorders 1,6764 A03AX13 Simeticone(O) 405384,432 g 0,5 g 1,6764 A03B BELLADONNA AND DERIVATIVES, PLAIN 0,0828 A03BA Belladonna alkaloids, tertiary amines 0,0728 A03BA01 Atropine(O, P) 12,81 g 0,0015 g 0,0177 A03BA01 Atropine(P) 40,02 g 0,0015 g 0,0552
A03BB Belladonna alkaloids, semisynthetic, quaternary ammonium compounds
0,0100
A03BB01 Hyoscine butylbromide(O) 21,4 g 0,06 g 0,0007
1/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day A03BB01 Hyoscine butylbromide(P) 266,8 g 0,06 g 0,0092 A03BB01 Hyoscine butylbromide(R) 1,92 g 0,06 g 0,0001 A03F PROPULSIVES 0,8605 A03FA Propulsives 0,8605 A03FA01 Metoclopramide(O) 10342 g 0,03 g 0,7128 A03FA01 Metoclopramide(P) 1687,1 g 0,03 g 0,1163 A03FA03 Domperidone(O) 455,91 g 0,03 g 0,0314 A04 ANTIEMETICS AND ANTINAUSEANTS 0,1210 A04A ANTIEMETICS AND ANTINAUSEANTS 0,1210 A04AA Serotonin (5-HT3) antagonists 0,1122 A04AA01 Ondansetron(P) 113,02 g 0,016 g 0,0146 A04AA02 Granisetron(O) 60,23 g 0,002 g 0,0623 A04AA02 Granisetron(P) 49,83 g 0,003 g 0,0343 A04AA05 Palonosetron(P) 0,008 g 0,25 mg 0,0001 A04AA80 Palonosetron+Netupitant(O) 449 pieces 1 pieces 0,0009 A04AD Other antiemetics 0,0088 A04AD01 Scopolamine(TD) 10 pieces 1 pieces <0,0001 A04AD12 Aprepitant(O) 285,855 g 0,165 g 0,0036 A04AD81 Fosaprepitant(P) 238,35 g 0,095 g 0,0052 A05 BILE AND LIVER THERAPY 2,0881 A05A BILE THERAPY 0,5485 A05AA Bile acids and derivatives 0,5485 A05AA02 Ursodeoxycholic acid(O) 198962,5 g 0,75 g 0,5485 A05B LIVER THERAPY, LIPOTROPICS 1,5396 A05BA Liver therapy 1,5396 A05BA03 Silymarin(O) 2121160 pieces A05BA80 Phospholipids from Soya Beans(O) 1380900 pieces 3 pieces 0,9518 A05BA80 Phospholipids from Soya Beans(O) 1705700 pieces 6 pieces 0,5878 A05BA80 Phospholipids from Soya Beans(P) 975 pieces A05BA81 Silibinin(P) 56 g A06 DRUGS FOR CONSTIPATION 16,4173 A06A DRUGS FOR CONSTIPATION 16,4173 A06AB Contact laxatives 7,5294 A06AB02 Bisacodyl(O) 14242,8 g 0,01 g 2,9450 A06AB02 Bisacodyl(R) 986,3 g 0,01 g 0,2039 A06AB06 Senna glycosides(O) 6380 pieces 1 pieces 0,0132 A06AB08 Sodium picosulfate(O) 10551,9264 g 0,005 g 4,3637 A06AB80 Sodium picosulfate+Magnesium oxide+Citric acid(O) 3426 pieces 2 pieces 0,0035 A06AC Bulk-forming laxatives <0,0001 A06AC01 Hemicellulose of Ispaghula(O) 0,585 g 7 g <0,0001 A06AD Osmotically acting laxatives 7,9377 A06AD11 Lactulose(O) 24311273,4 g 6,7 g 7,5028 A06AD15 Macrogol(O) 2103400 g 10 g 0,4349
A06AD80 Macrogol+Sodium citrate+Citric acid+Sodium chloride+Potassium chloride(O)
21500 ml
A06AD81 Sodium sulphate, anhydrous+Potassium chloride+Sodium chloride+Macrogol+Sodium hydrogen carbonate(O)
40940 pieces
A06AD83 Macrogol+Sodium sulphate, anhydrous+Sodium chloride+Potassium chloride+Ascorbic acid+Sodium ascorbate(O)
5843 pieces
A06AD85 Sodium sulphate, anhydrous+magnesium sulfate heptahydrate+Potassium sulphate(O)
934912 ml
A06AG Enemas 0,9313 A06AG11 Laurilsulfate, incl. combinations+Sorbitol+Sodium citrate(R) 450392 pieces 1 pieces 0,9313 A06AH Peripheral opioid receptor antagonists 0,0189 A06AH03 Naloxegol(O) 228,75 g 25 mg 0,0189
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
4,6470
A07A INTESTINAL ANTIINFECTIVES 0,0010 A07AA Antibiotics 0,0010
2/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day A07AA02 Nystatin(O) 60000000 U 1500000 U 0,0001 A07AA11 Rifaximin(O) 252 g 0,6 g 0,0009 A07AA12 Fidaxomicin(O) 4 g 0,4 g <0,0001 A07B INTESTINAL ADSORBENTS 0,5281 A07BC Other intestinal adsorbents 0,5281 A07BC05 Diosmectidum(O) 2298540 g 9 g 0,5281 A07C ELECTROLYTES WITH CARBOHYDRATES A07CA Oral rehydration salt formulations
A07CA80 Sodium chloride+Potassium chloride+Sodium citrate+Glucose(O) 48820 pieces
A07D ANTIPROPULSIVES 1,0787 A07DA Antipropulsives 1,0787 A07DA03 Loperamide(O) 5217,02 g 0,01 g 1,0787 A07E INTESTINAL ANTIINFLAMMATORY AGENTS 2,2662 A07EA Corticosteroids acting locally 0,0088 A07EA06 Budesonide(O) 38,4 g 0,009 g 0,0088 A07EA06 Budesonide(R) 2,5375 g A07EC Aminosalicylic acid and similar agents 2,2574 A07EC01 Sulfasalazine(O) 791900 g 2 g 0,8187 A07EC02 Mesalazine(O) 953300 g 1,5 g 1,3141 A07EC02 Mesalazine(R) 90360 g 1,5 g 0,1246 A07F ANTIDIARRHEAL MICROORGANISMS 0,7730 A07FA Antidiarrheal microorganisms 0,7730 A07FA02 Saccharomyces boulardii(O) 373845 g 1 g 0,7730 A07X OTHER ANTIDIARRHEALS A07XA Other antidiarrheals A07XA04 Racecadotril(O) 3490,64 g A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0649 A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0649 A08AA Centrally acting antiobesity products 0,0643 A08AA62 Bupropione+Naltrexone(O) 124432 pieces 4 pieces 0,0643 A08AB Peripherally acting antiobesity products 0,0006 A08AB01 Orlistat(O) 105,84 g 0,36 g 0,0006 A09 DIGESTIVES, INCL. ENZYMES 1,6015 A09A DIGESTIVES, INCL. ENZYMES 1,6015 A09AA Enzyme preparations 1,6015 A09AA02 Lipase+Amylase+Protease(O) 3098159 pieces 4 pieces 1,6015 A10 DRUGS USED IN DIABETES 65,0155 A10A INSULINS AND ANALOGUES 16,1124 A10AB Insulins and analogues for injection, fast-acting 6,0895 A10AB01 Insulin (human)(P) 996000 U 40 U 0,0515 A10AB04 Insulin lispro(P) 22677000 U 40 U 1,1722 A10AB05 Insulin aspart(P) 81877500 U 40 U 4,2325 A10AB06 Insulin glulisine(P) 12250500 U 40 U 0,6333 A10AC Insulins and analogues for injection, intermediate-acting 0,0743 A10AC01 Insulin (human)(P) 1437000 U 40 U 0,0743
A10AD Insulins and analogues for injection, intermediate- or long-acting combined with fast-acting
0,9251
A10AD04 Insulin lispro(P) 5487000 U 40 U 0,2836 A10AD05 Insulin aspart(P) 12409500 U 40 U 0,6415 A10AE Insulins and analogues for injection, long-acting 9,0235 A10AE04 Insulin glargine(P) 100768500 U 40 U 5,2090 A10AE05 Insulin detemir(P) 51253500 U 40 U 2,6494 A10AE06 Insulin degludec(P) 18664500 U 40 U 0,9648 A10AE54 Insulin glargine+Lixisenatide(P) 3873000 U 40 U 0,2002 A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS 48,9031 A10BA Biguanides 20,7978 A10BA02 Metformin(O) 20116659 g 2 g 20,7978 A10BB Sulfonylureas 12,7685 A10BB07 Glipizide(O) 919,2 g 0,01 g 0,1901
3/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day A10BB09 Gliclazide(O) 206602,2 g 0,06 g 7,1199 A10BB12 Glimepiride(O) 5279,79 g 0,002 g 5,4586 A10BD Combinations of oral blood glucose lowering drugs 6,9312 A10BD07 Metformin+Sitagliptin(O) 2027816 pieces 2 pieces 2,0965 A10BD08 Metformin+Vildagliptin(O) 1276740 pieces 2 pieces 1,3200 A10BD10 Metformin+Saxagliptin(O) 335820 pieces 2 pieces 0,3472 A10BD11 Metformin+Linagliptin(O) 1038300 pieces 2 pieces 1,0735 A10BD15 Metformin+Dapagliflozin(O) 547456 pieces 2 pieces 0,5660 A10BD19 Linagliptin+Empagliflozin(O) 143970 pieces 1 pieces 0,2977 A10BD20 Metformin+Empagliflozin(O) 1010580 pieces 2 pieces 1,0448 A10BD21 Saxagliptin+Dapagliflozin(O) 87836 pieces 1 pieces 0,1816 A10BD23 Metformin+Ertugliflozin(O) 1960 pieces 1 pieces 0,0041 A10BF Alpha glucosidase inhibitors 0,0009 A10BF01 Acarbose(O) 131,25 g 0,3 g 0,0009 A10BG Thiazolidinediones 0,1301 A10BG03 Pioglitazone(O) 1887,06 g 0,03 g 0,1301 A10BH Dipeptyl peptidase 4 (DPP-4) inhibitors 3,9646 A10BH01 Sitagliptin(O) 59508,4 g 0,1 g 1,2305 A10BH02 Vildagliptin(O) 8541 g 0,1 g 0,1766 A10BH03 Saxagliptin(O) 567,6 g 5 mg 0,2347 A10BH05 Linagliptin(O) 5616,75 g 5 mg 2,3228 A10BJ Glucagon-like peptide-1 (GLP-1) analogues 2,0412 A10BJ01 Exenatide(P) 7,72 g 0,286 mg 0,0558 A10BJ02 Liraglutide(P) 911,232 g 1,5 mg 1,2561 A10BJ03 Lixisenatide(P) 0,8871 g 20 mcg 0,0917 A10BJ05 Dulaglutide(P) 14,037 g 0,16 mg 0,1814 A10BJ06 Semaglutide(P) 24,269 g 0,11 mg 0,4562 A10BK Sodium-glucose co-transporter 2 (SGLT2) inhibitors 2,2688 A10BK01 Dapagliflozin(O) 4434,15 g 10 mg 0,9169 A10BK03 empagliflozin(O) 11436,75 g 17,5 mg 1,3513 A10BK04 Ertugliflozin(O) 2,94 g 10 mg 0,0006 A11 VITAMINS 12,5386 A11A MULTIVITAMINS, COMBINATIONS 1,4917 A11AA Multivitamins with minerals 1,4917 A11AA03 Multivitamins+Mineral elements(O) 721440 pieces 1 pieces 1,4917 A11B MULTIVITAMINS, PLAIN 0,0003 A11BA Multivitamins, plain 0,0003 A11BA80 Multivitamins(O) 1250 ml 10 ml 0,0003 A11C VITAMIN A AND D, INCL. COMBINATIONS OF THE TWO 2,4546 A11CC Vitamin D and analogues 2,4546 A11CC04 Calcitriol(O) 0,0974 g 0,001 mg 0,2013 A11CC05 Colecalciferol(O) 435900000 U 400 U 2,2533 A11CC05 Colecalciferol(P) 10000000 U
A11D VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN B6 AND B12
1,8820
A11DA Vitamin B1, plain 0,3818 A11DA01 Thiamine(P) 9232 g 0,05 g 0,3818 A11DA03 Benfotiamine(O) 1747420 pieces A11DB Vitamin B1 in combination with vitamin B6 and/or vitamin B12 1,5002 A11DB80 Thiamine+Pyridoxine(P) 3300 pieces 1 pieces 0,0068 A11DB81 Benfotiamine+Pyridoxine(O) 206250 pieces 3 pieces 0,1422 A11DB84 Thiamine+Pyridoxine+Cyanocobalamin(O) 572570 pieces 1 pieces 1,1839 A11DB85 Thiamine+Pyridoxine+Cyanocobalamin+Lidocaine(P) 80920 pieces 1 pieces 0,1673 A11E VITAMIN B-COMPLEX, INCL. COMBINATIONS 0,6135 A11EA Vitamin B-complex, plain 0,6135
A11EA80 Thiamine+Nicotinamide+Riboflavin+Calcium pantothenate+Pyridoxine(O)
296700 pieces 1 pieces 0,6135
A11G ASCORBIC ACID (VITAMIN C), INCL. COMBINATIONS 0,1727 A11GA Ascorbic acid (vitamin C), plain 0,1727 A11GA01 Ascorbic acid(P) 16702,5 g 0,2 g 0,1727
4/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day A11H OTHER PLAIN VITAMIN PREPARATIONS 0,0640 A11HA Other plain vitamin preparations 0,0640 A11HA02 Pyridoxine(O) 90 g 0,16 g 0,0012 A11HA02 Pyridoxine(P) 4434,5 g 0,16 g 0,0573 A11HA03 Tocopherol(O) 40 g 0,2 g 0,0004 A11HA08 Tocofersolan(O) 495 g 0,2 g 0,0051 A11J OTHER VITAMIN PRODUCTS, COMBINATIONS 5,8598 A11JB Vitamins with minerals 5,8598 A11JB81 Pyridoxine+Magnesium(O) 7201900 pieces 4 pieces 3,7229
A11JB82 Thiamine+Riboflavin+Pyridoxine+Cyanocobalamin+Ascorbic acid+Biotin+Nicotinamide+Calcium pantothenate+Calcium+Magnesium+Folic acid+Zinc(O)
1033470 pieces 1 pieces 2,1369
A12 MINERAL SUPPLEMENTS 9,0463 A12A CALCIUM 5,4182 A12AA Calcium 0,7933 A12AA03 Calcium gluconate(P) 24775 g 3 g 0,0171 A12AA04 Calcium carbonate(O) 1126150 g 3 g 0,7762 A12AX Calcium, combinations with vitamin D and/or other drugs 4,6249 A12AX80 Calcium+Colecalciferol(O) 600000 pieces 1 pieces 1,2406 A12AX80 Calcium+Colecalciferol(O) 3273480 pieces 2 pieces 3,3843 A12B POTASSIUM 3,0809 A12BA Potassium 3,0809 A12BA01 Potassium chloride(O) 319140 g 3 g 0,2200 A12BA02 Potassium citrate(O) 432 g 4 g 0,0002 A12BA80 Potassium chloride+Potassium hydrogen carbonate(O) 7900 pieces A12BA81 Potassium aspartate+Magnesium aspartate(O) 4102350 pieces 3 pieces 2,8275 A12BA81 Potassium aspartate+Magnesium aspartate(P) 16085 pieces 1 pieces 0,0333 A12C OTHER MINERAL SUPPLEMENTS 0,5472 A12CC Magnesium 0,5472 A12CC04 Magnesium citrate(O) 529247,912 g 2 g 0,5472 A12CX Other mineral products A12CX83 Phosphate(O) 11200 pieces A14 ANABOLIC AGENTS FOR SYSTEMIC USE 0,0021 A14A ANABOLIC STEROIDS 0,0021 A14AB Estren derivatives 0,0021 A14AB01 Nandrolone(P) 2 g 0,002 g 0,0021 A14B OTHER ANABOLIC AGENTS A14BX Other anabolic agents A14BX80 Riboxine(O) 90 g A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS 0,5117 A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS 0,5117 A16AA Amino acids and derivatives 0,0022 A16AA01 Levocarnitine(O) 1680 g 2 g 0,0017 A16AA02 Ademetionine(O) 395 g A16AA04 Mercaptamine(O) 120 g 2 g 0,0001 A16AA05 Carglumic acid(O) 22 g 0,2 g 0,0002 A16AA06 Betaine(O) 180 g 6 g 0,0001 A16AA80 L-arginiin(O) 90 g A16AA81 Glycine(O) 900 g A16AB Enzymes 0,0063 A16AB02 Imiglucerase(P) 196400 U 300 U 0,0014 A16AB03 Agalsidase alfa(P) 1,323 g 0,001 g 0,0027 A16AB04 Agalsidase beta(P) 2,32 g 0,005 g 0,0010 A16AB07 Alglucosidase alfa(P) 60 g 0,1 g 0,0012 A16AB09 Idursulfase(P) 1,344 g A16AX Various alimentary tract and metabolism products 0,5033 A16AX01 Thioctic acid(O) 142794 g 0,6 g 0,4921 A16AX01 Thioctic acid(P) 327 g 0,6 g 0,0011 A16AX03 Sodium phenylbutyrate(O) 3000 g 20 g 0,0003 A16AX05 Zinc(O) 681,25 g 0,15 g 0,0094
5/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day A16AX07 Sapropterin(O) 684 g A16AX10 Eliglustat(O) 18,816 g 0,168 g 0,0002 A16AX15 Telotristat(O) 45 g 0,75 g 0,0001 A16AX80 Creatine(O) 450 g A16AX81 Copper histidine(P) 0,105 g B BLOOD AND BLOOD FORMING ORGANS 107,7585 B01 ANTITHROMBOTIC AGENTS 83,1567 B01A ANTITHROMBOTIC AGENTS 83,1567 B01AA Vitamin K antagonists 2,9920 B01AA03 Warfarin(O) 10852,5 g 0,0075 g 2,9920 B01AB Heparin group 3,1593 B01AB01 Heparin sodium(P) 680500000 U 10000 U 0,1407 B01AB04 Dalteparin sodium(P) 1850000 U 2500 U 0,0015 B01AB05 Enoxaparin sodium(hem, P) 590108000 U 2000 U 0,6101 B01AB05 Enoxaparin sodium(P) 1827824000 U 2000 U 1,8897 B01AB06 Nadroparin calcium(P) 10849000 U 2850 U 0,0079 B01AB12 Bemiparin sodium(P) 615835000 U 2500 U 0,5093 B01AC Platelet aggregation inhibitors, excl. heparin 57,8181 B01AC04 Clopidogrel(O) 157415,25 g 0,075 g 4,3399 B01AC06 Acetylsalicylic acid (O) 5467750 pieces 1 pieces 11,3058 B01AC07 Dipyridamole(O) 44,1 g 0,4 g 0,0002 B01AC09 Epoprostenol(P) 0,003 g B01AC11 Iloprost(I) 0,121 g 0,15 mg 0,0017 B01AC11 Iloprost(P) 0,009 g 50 mcg 0,0004 B01AC16 Eptifibatide(P) 72,56 g 0,2 g 0,0008 B01AC24 Ticagrelor(O) 97450,08 g 0,18 g 1,1194 B01AC80 Acetylsalicylic acid +Magnesium oxide(O) 19852800 pieces 1 pieces 41,0500 B01AD Enzymes 0,0024 B01AD01 Streptokinase(P) 107500000 U 1500000 U 0,0001 B01AD02 Alteplase(P) 90,83 g 0,1 g 0,0019 B01AD11 Tenecteplase(P) 6,75 g 0,04 g 0,0003 B01AE Direct thrombin inhibitors 2,7763 B01AE07 Dabigatran etexilate(O) 402802,4 g 0,3 g 2,7763 B01AF Direct factor Xa inhibitors 16,4061 B01AF01 Rivaroxaban(O) 88914,18 g 0,02 g 9,1925 B01AF02 Apixaban(O) 34884,9 g 10 mg 7,2132 B01AF03 Edoxaban(O) 10,8 g 60 mg 0,0004 B01AX Other antithrombotic agents 0,0027 B01AX05 Fondaparinux sodium(P) 3,225 g 0,0025 g 0,0027 B02 ANTIHEMORRHAGICS 0,1720 B02A ANTIFIBRINOLYTICS 0,1528 B02AA Amino acids 0,1528 B02AA01 Aminocaproic acid(P) 12980 g 16 g 0,0017 B02AA02 Tranexamic acid(O) 108820 g 2 g 0,1125 B02AA02 Tranexamic acid(P) 37348 g 2 g 0,0386 B02B VITAMIN K AND OTHER HEMOSTATICS 0,0193 B02BA Vitamin K 0,0040 B02BA01 Phytomenadione(O, P) 36,94 g 0,02 g 0,0038 B02BA01 Phytomenadione(P) 1,62 g 0,02 g 0,0002 B02BB Fibrinogen 0,0001 B02BB01 Fibrinogen human(P) 135 g 5 g 0,0001 B02BC Local hemostatics B02BC81 Fibrinogen human+Human thrombin(epil) 665 pieces B02BD Blood coagulation factors B02BD01 Human prothrombin complex(P) 273000 U B02BD02 Human coagulation factor VIII(P) 3261500 U B02BD03 Factor VIII inhibitor bypassing activity(P) 940000 U B02BD04 Human coagulation factor IX(P) 655200 U B02BD05 Human coagulation factor VII(P) 192000 U
6/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B02BD06 Von Willebrand factor, human+Human coagulation factor VIII(P) 2369250 U
B02BD08 Coagulation factor VIIa(P) 6350000 U B02BD10 Von Willebrand factor, human(P) 26000 U B02BD80 Turoctocog alfa(P) 50000 U B02BD81 Simoctocog alfa(P) 2248500 U B02BD83 Efmoroctocog alfa(P) 76000 U B02BX Other systemic hemostatics 0,0152 B02BX01 Etamsylate(P) 1010 g B02BX04 Romiplostim(P) 0,02 g 30 mcg 0,0014 B02BX05 Eltrombopag(O) 325,5 g 50 mg 0,0135 B02BX06 Emicizumab(P) 2,7 g 15 mg 0,0004 B03 ANTIANEMIC PREPARATIONS 24,4292 B03A IRON PREPARATIONS 4,2694 B03AA Iron bivalent, oral preparations 2,5532 B03AA07 Ferrous sulphate(O) 246957 g 0,2 g 2,5532 B03AB Iron trivalent, oral preparations B03AB80 Iron (III) hydroxide polymaltose complex(O) 82826,5 g B03AC Iron, parenteral preparations 0,0931 B03AC01 Dextriferron(P) 804,5 g 0,1 g 0,0166 B03AC02 Iron (III) hydroxide sucrose complex(P) 1409,5 g 0,1 g 0,0291 B03AC06 Iron (III)-hydroxide dextran complex(P) 1604 g 0,1 g 0,0332 B03AC80 Iron (III) isomaltoside 1000 complex(P) 685 g 0,1 g 0,0142 B03AD Iron in combination with folic acid 1,6231 B03AD02 Ferrous fumarate+Folic acid(O) 596310 pieces 1 pieces 1,2330 B03AD03 Ferrous sulphate+Folic acid(O) 188650 pieces 1 pieces 0,3901 B03AE Iron in other combinations
B03AE81 Ferrous gluconate+Manganese gluconate+Copper gluconate(O) 1680000 ml
B03AE82 Ferrous fumarate+Folic acid+Ascorbic acid(O) 52270 pieces B03B VITAMIN B12 AND FOLIC ACID 19,2386 B03BA Vitamin B12 (cyanocobalamin and analogues) 6,5241 B03BA01 Cyanocobalamin(O) 11,25 g 1 mg 0,0233 B03BA01 Cyanocobalamin(P) 62,69 g 0,02 mg 6,4813 B03BA03 Hydroxocobalamin(P) 0,189 g 0,02 mg 0,0195 B03BB Folic acid and derivatives 12,7145 B03BB01 Folic acid(O) 2459,625 g 0,4 mg 12,7145 B03X OTHER ANTIANEMIC PREPARATIONS 0,9213 B03XA Other antianemic preparations 0,9213 B03XA02 Darbepoetin alfa(P) 1,4251 g 0,0045 mg 0,6548 B03XA03 Methoxy polyethylene glycol-epoetin beta(P) 0,3031 g 4 mcg 0,1567 B03XA80 Epoetin beta(P) 53100000 U 1000 U 0,1098 B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS B05A BLOOD AND RELATED PRODUCTS B05AA Blood substitutes and plasma protein fractions B05AA01 Albumin(P) 635690 g B05AA06 Gelatin agents(P) 9215000 ml B05AA80 Hydroxyethyl starch+Sodium chloride(P) 16000 ml B05AA81 Dextran+Sodium chloride(P) 45500 ml
B05AA83 Gelatine+Sodium chloride+Potassium chloride+Magnesium chloride+Sodium lactate(P)
357500 ml
B05AA86 human plasma proteins(P) 242000 ml B05B I.V. SOLUTIONS B05BA Solutions for parenteral nutrition B05BA01 Amino acids(P) 646900 ml B05BA02 Fat emulsions(P) 166000 ml B05BA03 Carbohydrates(P) 4000 g B05BA03 Carbohydrates(P) 71342500 ml B05BA10 Combinations(P) 15803944 ml B05BB Solutions affecting the electrolyte balance
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day B05BB01 Electrolytes(P) 172929500 ml B05BB03 Trometamol(P) 200 ml B05BC Solutions producing osmotic diuresis B05BC01 Mannitol(P) 906000 ml B05C IRRIGATING SOLUTIONS B05CX Other irrigating solutions B05CX10 Combinations(NA) 216000 ml B05D PERITONEAL DIALYTICS B05DA Isotonic solutions B05DA80 Isotonic solutions(P) 8390000 ml B05DB Hypertonic solutions B05DB80 hypertonic solutions(P) 142416000 ml
B05DB81 Amino acids+Sodium chloride+Calcium chloride dihydrate+Magnesium chloride hexahydrate+Sodium lactate(P)
570000 ml
B05Z HEMODIALYTICS AND HEMOFILTRATES B05ZB Hemofiltrates
B05ZB80 Sodium chloride+Potassium chloride+Calcium chloride dihydrate+Magnesium chloride+Glucose+Sodium hydrogen carbonate(P)
21960000 ml
B05ZB82 Calcium chloride dihydrate+Magnesium chloride hexahydrate+Sodium chloride+Sodium hydrogen carbonate+Potassium chloride+Disodium phosphate dihydrate(P)
13690000 ml
B05ZB84 Calcium chloride dihydrate+Magnesium chloride hexahydrate+Lactic acid+Sodium hydrogen carbonate+Sodium chloride(P)
780000 ml
B05ZB85 Sodium citrate+Sodium chloride(P) 2429000 ml
B05ZB86 Magnesium chloride hexahydrate+Sodium chloride+Potassium chloride+Disodium phosphate dihydrate+Sodium hydrogen carbonate(P)
1340000 ml
B05X I.V. SOLUTION ADDITIVES B05XA Electrolyte solutions B05XA01 Potassium chloride(P) 975 g B05XA01 Potassium chloride(P) 3432400 ml B05XA02 Sodium hydrogen carbonate(P) 1540500 ml B05XA03 Sodium chloride(P) 494726200 ml B05XA05 Magnesium sulphate(P) 418300 ml B05XA06 Potassium dihydrogen phosphate(P) 400 ml B05XA07 Calcium chloride(P) 242600 ml B05XA14 Sodium glycerophosphate, hydrated(P) 100200 ml B05XA80 Electrolytes(P) 112700 ml B05XB Amino acids B05XB01 Arginine(P) 3100 ml B05XB02 Alanyl glutamine(P) 39500 ml B05XC Vitamins B05XC80 Vitamins(P) 848,12 g B05XC80 Vitamins(P) 221500 ml B06 OTHER HEMATOLOGICAL AGENTS 0,0006 B06A OTHER HEMATOLOGICAL AGENTS 0,0006 B06AC Drugs usedin hereditary angioedema 0,0006 B06AC01 C1-inhibitor(P) 106000 U 1400 U 0,0002 B06AC02 Icatibant(P) 3,18 g 0,03 g 0,0002 B06AC04 Conestat alfa(P) 302400 U 3500 U 0,0002 C CARDIOVASCULAR SYSTEM 429,8975 C01 CARDIAC THERAPY 23,3946 C01A CARDIAC GLYCOSIDES 2,4668 C01AA Digitalis glycosides 2,4668 C01AA05 Digoxin(O) 295,775 g 0,25 mg 2,4463 C01AA05 Digoxin(P) 2,4625 g 0,25 mg 0,0204
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day C01AA06 Lanatoside C(O) 0,045 g 0,001 g 0,0001 C01B ANTIARRHYTHMICS, CLASS I AND III 5,7179 C01BA Antiarrhythmics, class Ia C01BA13 Hydroquinidine(O) 252 g C01BB Antiarrhythmics, class Ib 0,0236 C01BB02 Mexiletine(O) 120 g 0,8 g 0,0003 C01BB80 Aethacizin(O) 2250 g 0,2 g 0,0233 C01BC Antiarrhythmics, class Ic 3,7064 C01BC03 Propafenone(O) 517383 g 0,3 g 3,5660 C01BC03 Propafenone(P) 568,75 g 0,3 g 0,0039 C01BC04 Flecainide(O) 13178 g 0,2 g 0,1362 C01BC04 Flecainide(P) 24 g 0,2 g 0,0002 C01BD Antiarrhythmics, class III 1,9879 C01BD01 Amiodarone(O) 185604 g 0,2 g 1,9189 C01BD01 Amiodarone(P) 5508,75 g 0,2 g 0,0570 C01BD07 Dronedarone(O) 4656 g 0,8 g 0,0120 C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES 0,8703 C01CA Adrenergic and dopaminergic agents 0,8692 C01CA01 Etilefrine(O) 3,825 g 0,05 g 0,0002 C01CA02 Isoprenaline(P) 0,537 g 0,09 g <0,0001 C01CA03 Norepinephrine(P) 330,244 g 0,006 g 0,1138 C01CA04 Dopamine(P) 1327 g 0,5 g 0,0055 C01CA06 Phenylephrine(P) 230,7 g 0,004 g 0,1193 C01CA07 Dobutamine(P) 772,5 g 0,5 g 0,0032 C01CA17 Midodrine(O) 4,375 g 0,03 g 0,0003 C01CA24 Epinephrine(I) 3,834 g C01CA24 Epinephrine(P) 140,712 g 0,5 mg 0,5819 C01CA26 Ephedrine(P) 1090,75 g 0,05 g 0,0451 C01CE Phosphodiesterase inhibitors 0,0006 C01CE02 Milrinone(P) 14,88 g 0,05 g 0,0006 C01CX Other cardiac stimulants 0,0004 C01CX08 Levosimendan(P) 2,25 g 11 mg 0,0004 C01CX80 Ammonia(I) 1162880 ml C01D VASODILATORS USED IN CARDIAC DISEASES 6,2037 C01DA Organic nitrates 6,2008 C01DA02 Glyceryl trinitrate(P) 224,1 g C01DA02 Glyceryl trinitrate(SL) 511,128 g 0,0025 g 0,4227 C01DA08 Isosorbide dinitrate(O) 9764 g 0,06 g 0,3365 C01DA08 Isosorbide dinitrate(SL) 258,75 g 0,02 g 0,0268 C01DA14 Isosorbide mononitrate(O) 104750,2 g 0,04 g 5,4148 C01DX Other vasodilatators used in cardiac diseases 0,0029 C01DX80 Meldonium(O) 1050 g 0,75 g 0,0029 C01E OTHER CARDIAC PREPARATIONS 8,1360 C01EA Prostaglandins 0,0003 C01EA01 Alprostadil(P) 0,0644 g 0,5 mg 0,0003 C01EB Other cardiac preparations 8,1357 C01EB10 Adenosine(P) 92,312 g 0,015 g 0,0127 C01EB15 Trimetazidine(O) 149704,8 g 0,04 g 7,7387 C01EB16 Ibuprofen(P) 0,92 g 0,03 g 0,0001 C01EB17 Ivabradine(O) 1590,12 g 0,01 g 0,3288 C01EB18 Ranolazine(O) 39690 g 1,5 g 0,0547 C01EB21 Regadenoson(P) 0,148 g 0,4 mg 0,0008 C01EB80 Hawthorn berry(O) 92720 ml C02 ANTIHYPERTENSIVES 3,7643 C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING 2,4247 C02AC Imidazoline receptor agonists 2,4247 C02AC01 Clonidine(O) 5,025 g 0,45 mg 0,0231 C02AC01 Clonidine(P) 3,901 g 0,45 mg 0,0179 C02AC05 Moxonidine(O) 345,8476 g 0,3 mg 2,3837 C02C ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING 1,3058
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day C02CA Alpha-adrenoreceptor antagonists 1,3058 C02CA01 Prazosin(O) 2,91 g 0,005 g 0,0012 C02CA04 Doxazosin(O) 2523,652 g 0,004 g 1,3046 C02D ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON 0,0007 C02DD Nitroferricyanide derivatives 0,0007 C02DD01 Sodium nitroprusside(P) 16 g 0,05 g 0,0007 C02K OTHER ANTIHYPERTENSIVES 0,0331 C02KX Antihypertensives for pulmonary arterial hypertension 0,0331 C02KX01 Bosentan(O) 1225 g 0,25 g 0,0101 C02KX02 Ambrisentan(O) 42,75 g 7,5 mg 0,0118 C02KX04 Macitentan(O) 3 g 10 mg 0,0006 C02KX05 Riociguat(O) 23,058 g 4,5 mg 0,0106 C03 DIURETICS 26,1197 C03A LOW-CEILING DIURETICS, THIAZIDES 1,4557 C03AA Thiazides, plain 1,4557 C03AA03 Hydrochlorothiazide(O) 17600,5 g 0,025 g 1,4557 C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES 2,3798 C03BA Sulfonamides, plain 2,3798 C03BA11 Indapamide(O) 2877,285 g 2,5 mg 2,3798 C03C HIGH-CEILING DIURETICS 18,9909 C03CA Sulfonamides, plain 18,9909 C03CA01 Furosemide(O) 72206,2 g 0,04 g 3,7326 C03CA01 Furosemide(P) 5071,8 g 0,04 g 0,2622 C03CA04 Torasemide(O) 108268,65 g 0,015 g 14,9246 C03CA04 Torasemide(P) 519,4 g 0,015 g 0,0716 C03D POTASSIUM-SPARING AGENTS 3,2787 C03DA Aldosterone antagonists 3,2787 C03DA01 Spironolactone(O) 118923,75 g 0,075 g 3,2787
C03E DIURETICS AND POTASSIUM-SPARING AGENTS IN COMBINATION
0,0146
C03EA Low-ceiling diuretics and potassium-sparing agents 0,0146 C03EA81 Hydrochlorothiazide+Amiloride(O) 7050 pieces 1 pieces 0,0146 C04 PERIPHERAL VASODILATORS 2,6811 C04A PERIPHERAL VASODILATORS 2,6811 C04AC Nicotinic acid and derivatives 0,0002 C04AC01 Nicotinic acid(P) 15 g 0,2 g 0,0002 C04AD Purine derivatives 1,7456 C04AD02 Xantinol nicotinate(O) 297 g 0,9 g 0,0007 C04AD03 Pentoxifylline(O) 842104 g 1 g 1,7412 C04AD03 Pentoxifylline(P) 528 g 0,3 g 0,0036 C04AX Other peripheral vasodilators 0,9353 C04AX21 Naftidrofuryl(O) 271415 g 0,6 g 0,9353 C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids C05AA82 Hydrocortisone+Cinchocaine(R) 58620 pieces C05AA84 Fluocortolone+Lidocaine(R) 186520 pieces C05AA84 Fluocortolone+Lidocaine(R) 187095 g C05AE Muscle relaxants C05AE01 Glyceryl trinitrate(R) 30 g
C05AX Other agents for treatment of hemorrhoids and anal fissures for topical use
C05AX81 Xeroformium+Zinc sulphate+Extract of Belladonna(R) 2230 pieces C05AX83 Yeast cell extract+Shark liver oil(R) 25 g C05AX83 Yeast cell extract+Shark liver oil(R) 307452 pieces C05AX85 Hippopheae oleum(R) 30 pieces C05B ANTIVARICOSE THERAPY C05BA Heparins or heparinoids for topical use C05BA01 Chondroitin polysulfate(C) 51360 g
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day C05BA03 Heparin sodium(C) 7751250 g C05BB Sclerosing agents for local injection C05BB02 Lauromacrogol 400(P) 96,9 g C05C CAPILLARY STABILIZING AGENTS C05CA Bioflavonoids C05CA01 Rutoside(O) 249885 pieces C05CA03 Diosmin(O) 331950 g C05CA04 Troxerutin(C) 3455980 g C05CA04 Troxerutin(O) 212160 g C05CA53 Diosmin+Hesperidine(O) 2220 pieces C07 BETA BLOCKING AGENTS 55,1998 C07A BETA BLOCKING AGENTS 55,1988 C07AA Beta blocking agents, non-selective 1,7930 C07AA05 Propranolol(O) 47315,5 g 0,16 g 0,6115 C07AA07 Sotalol(O) 91423,2 g 0,16 g 1,1815 C07AB Beta blocking agents, selective 52,7835 C07AB02 Metoprolol(O) 1907206,1 g 0,15 g 26,2904 C07AB02 Metoprolol(P) 97,6 g 0,15 g 0,0013 C07AB03 Atenolol(O) 19616,25 g 0,075 g 0,5408 C07AB07 Bisoprolol(O) 14796,3 g 0,01 g 3,0595 C07AB09 Esmolol(P) 0,5 g 2,5 g <0,0001 C07AB12 Nebivolol(O) 55354,51 g 0,005 g 22,8915 C07AG Alpha and beta blocking agents 0,6223 C07AG01 Labetalol(O) 27925 g 0,6 g 0,0962 C07AG01 Labetalol(P) 1097,5 g 0,6 g 0,0038 C07AG02 Carvedilol(O) 9471,5625 g 0,0375 g 0,5223 C07B BETA BLOCKING AGENTS AND THIAZIDES 0,0010 C07BB Beta blocking agents, selective, and thiazides 0,0010 C07BB07 Bisoprolol+Hydrochlorothiazide(O) 480 pieces 1 pieces 0,0010 C08 CALCIUM CHANNEL BLOCKERS 46,5513
C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
44,9857
C08CA Dihydropyridine derivatives 44,9857 C08CA01 Amlodipine(O) 61417,5 g 0,005 g 25,3988 C08CA02 Felodipine(O) 6751,5 g 0,005 g 2,7920 C08CA05 Nifedipine(O) 16632,24 g 0,03 g 1,1464 C08CA06 Nimodipine(O) 459 g 0,3 g 0,0032 C08CA06 Nimodipine(P) 3,75 g 0,05 g 0,0002 C08CA08 Nitrendipine(O) 45226,74 g 0,02 g 4,6758 C08CA09 Lacidipine(O) 6492,976 g 0,004 g 3,3564 C08CA13 Lercanidipine(O) 36818,1 g 0,01 g 7,6129
C08D SELECTIVE CALCIUM CHANNEL BLOCKERS WITH DIRECT CARDIAC EFFECTS
1,5656
C08DA Phenylalkylamine derivatives 1,4753 C08DA01 Verapamil(O) 171228 g 0,24 g 1,4752 C08DA01 Verapamil(P) 12,65 g 0,24 g 0,0001 C08DB Benzothiazepine derivatives 0,0902 C08DB01 Diltiazem(O) 10474,2 g 0,24 g 0,0902 C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM 203,0954 C09A ACE INHIBITORS, PLAIN 75,3170 C09AA ACE inhibitors, plain 75,3170 C09AA01 Captopril(O) 942,5 g 0,05 g 0,0390 C09AA02 Enalapril(O) 43829,85 g 0,01 g 9,0628 C09AA02 Enalapril(P) 9,3625 g 0,01 g 0,0019 C09AA03 Lisinopril(O) 0,56 g 0,01 g 0,0001 C09AA04 Perindopril(O) 12741,54 g 0,004 g 6,5865 C09AA05 Ramipril(O) 65538,64 g 2,5 mg 54,2062 C09AA09 Fosinopril(O) 38351,6 g 0,015 g 5,2867 C09AA10 Trandolapril(O) 129,528 g 0,002 g 0,1339 C09B ACE INHIBITORS, COMBINATIONS 53,2135
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day C09BA ACE inhibitors and diuretics 28,4447 C09BA02 Enalapril+Hydrochlorothiazide(O) 3166190 pieces 1 pieces 6,5468 C09BA04 Perindopril+Indapamide(O) 8714640 pieces 1 pieces 18,0194 C09BA05 Ramipril+Hydrochlorothiazide(O) 1251870 pieces 1 pieces 2,5885 C09BA09 Fosinopril+Hydrochlorothiazide(O) 623854 pieces 1 pieces 1,2900 C09BB ACE inhibitors and calcium channel blockers 11,6784 C09BB03 Lisinopril+Amlodipine(O) 826200 pieces 1 pieces 1,7083 C09BB04 Perindopril+Amlodipine(O) 3760440 pieces 1 pieces 7,7755 C09BB07 Ramipril+Amlodipine(O) 715620 pieces 1 pieces 1,4797 C09BB10 Trandolapril+Verapamil(O) 345716 pieces 1 pieces 0,7148 C09BX ACE inhibitors, other combinations 13,0905 C09BX01 Perindopril+Amlodipine+Indapamide(O) 6330870 pieces 1 pieces 13,0905 C09C ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS), PLAIN 43,0625 C09CA Angiotensin II receptor blockers (ARBs), plain 43,0625 C09CA01 Losartan(O) 94693,7 g 0,05 g 3,9160 C09CA02 Eprosartan(O) 1226,4 g 0,6 g 0,0042 C09CA03 Valsartan(O) 157357,76 g 0,08 g 4,0671 C09CA06 Candesartan(O) 39225,568 g 0,008 g 10,1384 C09CA07 Telmisartan(O) 426417,76 g 0,04 g 22,0428 C09CA08 Olmesartan medoxomil(O) 27991,88 g 0,02 g 2,8940
C09D ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS), COMBINATIONS 31,5023
C09DA Angiotensin II receptor blockers (ARBs) and diuretics 14,7201 C09DA01 Losartan+Hydrochlorothiazide(O) 939154 pieces 1 pieces 1,9419 C09DA03 Valsartan+Hydrochlorothiazide(O) 825356 pieces 1 pieces 1,7066 C09DA06 Candesartan+Hydrochlorothiazide(O) 1044152 pieces 1 pieces 2,1590 C09DA07 Telmisartan+Hydrochlorothiazide(O) 4056654 pieces 1 pieces 8,3880 C09DA08 Olmesartan medoxomil+Hydrochlorothiazide(O) 253680 pieces 1 pieces 0,5245
C09DB Angiotensin II receptor blockers (ARBs) and calcium channel blockers 12,4258
C09DB01 Valsartan+Amlodipine(O) 154244 pieces 1 pieces 0,3189 C09DB02 Olmesartan medoxomil+Amlodipine(O) 2631132 pieces 1 pieces 5,4404 C09DB04 Telmisartan+Amlodipine(O) 3157952 pieces 1 pieces 6,5298 C09DB07 Candesartan+Amlodipine(O) 66080 pieces 1 pieces 0,1366 C09DX Angiotensin II receptor blockers (ARBs), other combinations 4,3564 C09DX01 Valsartan+Amlodipine+Hydrochlorothiazide(O) 2352 pieces 1 pieces 0,0049 C09DX03 Olmesartan medoxomil+Amlodipine+Hydrochlorothiazide(O) 1914808 pieces 1 pieces 3,9593 C09DX04 Valsartan+Sacubitril(O) 189728 pieces 1 pieces 0,3923 C10 LIPID MODIFYING AGENTS 69,0915 C10A LIPID MODIFYING AGENTS, PLAIN 67,6265 C10AA HMG CoA reductase inhibitors 66,5854 C10AA01 Simvastatin(O) 72665,36 g 0,03 g 5,0084 C10AA03 Pravastatin(O) 4533 g 0,03 g 0,3124 C10AA04 Fluvastatin(O) 15646,4 g 0,06 g 0,5392 C10AA05 Atorvastatin(O) 244735,5 g 0,02 g 25,3022 C10AA07 Rosuvastatin(O) 171315,16 g 0,01 g 35,4231 C10AB Fibrates 0,6214 C10AB05 Fenofibrate(O) 60108 g 0,2 g 0,6214 C10AC Bile acid sequestrants 0,0018 C10AC01 Colestyramine(O) 10000 g 14 g 0,0015 C10AC04 Colesevelam(O) 562,5 g 3,75 g 0,0003 C10AX Other lipid modifying agents 0,4179 C10AX09 Ezetimibe(O) 1964,76 g 0,01 g 0,4063 C10AX13 Evolocumab(P) 37,94 g 10 mg 0,0078 C10AX14 Alirocumab(P) 9,9 g 5,4 mg 0,0038 C10AX80 Omega-3-acid ethyl esters 90(O) 174692 pieces C10B LIPID MODIFYING AGENTS, COMBINATIONS 1,4650
C10BA HMG CoA reductase inhibitors in combination with other lipid modifying agents
0,6065
C10BA06 Rosuvastatin+Ezetimibe(O) 293310 pieces 1 pieces 0,6065
12/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day C10BX HMG CoA reductase inhibitors, other combinations 0,8585 C10BX03 Atorvastatin+Amlodipine(O) 170280 pieces 1 pieces 0,3521 C10BX11 Atorvastatin+Amlodipine+Perindopril(O) 235410 pieces 1 pieces 0,4868 C10BX15 Atorvastatin+Perindopril(O) 9510 pieces 1 pieces 0,0197 D DERMATOLOGICALS 1,8669 D01 ANTIFUNGALS FOR DERMATOLOGICAL USE 1,2267 D01A ANTIFUNGALS FOR TOPICAL USE D01AC Imidazole and triazole derivatives D01AC01 Clotrimazole(C) 200 ml D01AC01 Clotrimazole(C) 662762,2 g D01AC05 Isoconazole(C) 224100 g D01AC08 Ketoconazole(C) 419839,8 g D01AC08 Ketoconazole(C) 1463040 ml D01AC80 Isoconazole+Diflucortolone(C) 530370 g D01AC81 Clotrimazole+Hexamidine(C) 149040 g D01AE Other antifungals for topical use D01AE14 Ciclopirox(C) 4613,4 ml D01AE15 Terbinafine(C) 630651 g D01AE16 Amorolfine(C) 20 g D01AE16 Amorolfine(C) 29172,5 ml D01AE22 Naftifine(C) 216310 ml D01AE22 Naftifine(C) 290235 g D01B ANTIFUNGALS FOR SYSTEMIC USE 1,2267 D01BA Antifungals for systemic use 1,2267 D01BA01 Griseofulvin(O) 585 g 0,5 g 0,0024 D01BA02 Terbinafine(O) 148024,5 g 0,25 g 1,2243 D02 EMOLLIENTS AND PROTECTIVES D02A EMOLLIENTS AND PROTECTIVES D02AB Zinc products D02AB80 Zinc oxide(C) 409860 g D02AE Carbamide products D02AE01 Urea(C) 109450 g D02AF Salicylic acid preparations D02AF81 Salicylic acid+Lactic acid(C) 15 ml D02B PROTECTIVES AGAINST UV-RADIATION D02BA Protectives against UV-radiation for topical use D02BA01 4-Aminobenzoic acid(O) 14160 g D03 PREPARATIONS FOR TREATMENT OF WOUNDS AND ULCERS D03A CICATRIZANTS D03AX Other cicatrizants D03AX03 Dexpanthenol(C) 4235255 g D03AX81 Heparin sodium+Allantoin+Extract of Cepae(C) 129420 g D03AX83 Dexpanthenol+Chlorhexidine(C) 1952130 g D05 ANTIPSORIATICS 0,0536 D05A ANTIPSORIATICS FOR TOPICAL USE D05AA Tars D05AA85 Coal tar+Salicylic acid(C) 315400 ml D05AC Antracen derivatives D05AC01 Dithranol(C) 1500 g D05AX Other antipsoriatics for topical use D05AX02 Calcipotriol(C) 210 g D05AX80 Calcipotriol+Betamethasone(C) 822210 g D05B ANTIPSORIATICS FOR SYSTEMIC USE 0,0536 D05BB Retinoids for treatment of psoriasis 0,0536 D05BB02 Acitretin(O) 906,9 g 0,035 g 0,0536
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE D06AA Tetracycline and derivatives D06AA04 Tetracycline(C) 3035 g
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day D06AX Other antibiotics for topical use D06AX01 Fusidic acid(C) 212160 g D06AX02 Chloramphenicol(C) 375 g D06AX09 Mupirocin(C) 4335 g D06AX80 Bacitracin+Neomycin(C) 170440 g D06AX84 Chloramphenicol+Methyluracil(C) 1600 g D06B CHEMOTHERAPEUTICS FOR TOPICAL USE D06BA Sulfonamides D06BA01 Silver sulfadiazine(C) 1528200 g D06BB Antivirals D06BB03 Aciclovir(C) 257101 g D06BB04 Podophyllotoxin(C) 2826 ml D06BB06 Penciclovir(C) 4084 g D06BB10 Imiquimod(C) 3160 g D06BX Other chemotherapeutics D06BX01 Metronidazole (C) 136960 g D06BX02 Ingenol mebutate(C) 0,0002 g D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS D07A CORTICOSTEROIDS, PLAIN D07AA Corticosteroids, weak (group I) D07AA02 Hydrocortisone(C) 632620 g D07AB Corticosteroids, moderately potent (group II) D07AB09 Triamcinolone(C) 40290 g D07AC Corticosteroids, potent (group III) D07AC01 Betamethasone(C) 151155 g D07AC04 Fluocinolone acetonide(C) 30 g D07AC13 Mometasone(C) 325780 ml D07AC13 Mometasone(C) 1162600 g D07AC14 Methylprednisolone aceponate(C) 577100 g D07AC17 Fluticasone(C) 56400 g D07AD Corticosteroids, very potent (group IV) D07AD01 Clobetasol(C) 91200 ml D07AD01 Clobetasol(C) 935425 g D07B CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS D07BA Corticosteroids, weak, combinations with antiseptics D07BA80 Hydrocortisone+Chlorhexidine(C) 367740 g D07BC Corticosteroids, potent, combinations with antiseptics D07BC80 Betamethasone+Salicylic acid(C) 5105 g D07BC80 Betamethasone+Salicylic acid(C) 909000 ml D07C CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS D07CA Corticosteroids, weak, combinations with antibiotics D07CA83 Hydrocortisone+Fusidic acid(C) 82290 g D07CC Corticosteroids, potent, combinations with antibiotics D07CC80 Betamethasone+Fusidic acid(C) 522780 g D07CC83 Betamethasone+Gentamicin(C) 200 g D07X CORTICOSTEROIDS, OTHER COMBINATIONS D07XA Corticosteroids, weak, other combinations D07XA81 Prednisolone+Salicylic acid(C) 199500 ml D07XC Corticosteroids, potent, other combinations D07XC03 Mometasone+Salicylic acid(C) 10350 g D08 ANTISEPTICS AND DISINFECTANTS D08A ANTISEPTICS AND DISINFECTANTS D08AG Iodine products D08AG02 Povidone, iodinated(C) 969130 ml D08AG02 Povidone, iodinated(C) 3450150 g D08AG03 Iodine(C) 795620 ml D08AJ Quaternary ammonium compounds D08AJ81 Octenidine+Phenoxyethanol(C) 9997450 ml D08AX Other antiseptics and disinfectants D08AX82 Tar+Castor oil+Xeroformium(C) 9960 g
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day D08AX83 Brilliant Green(C) 286130 ml D10 ANTI-ACNE PREPARATIONS 0,5178 D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE D10AD Retinoids for topical use in acne D10AD01 Tretinoin(C) 30570 g D10AD03 Adapalene(C) 134130 g D10AD80 Adapalene+Benzoyl peroxide(C) 25410 g D10AD81 Tretinoin+Erythromycin(C) 58080 g D10AF Antiinfectives for treatment of acne D10AF02 Erythromycin(C) 256900 ml D10AF81 Clindamycin+Benzoyl peroxide(C) 301575 g D10AF82 Clindamycin+Tretinoin(C) 150720 g D10AX Other anti-acne preparations for topical use D10AX03 Azelaic acid(C) 262410 g D10B ANTI-ACNE PREPARATIONS FOR SYSTEMIC USE 0,5178 D10BA Retinoids for treatment of acne 0,5178 D10BA01 Isotretinoin(O) 7513,2 g 0,03 g 0,5178 D11 OTHER DERMATOLOGICAL PREPARATIONS 0,0687 D11A OTHER DERMATOLOGICAL PREPARATIONS 0,0687 D11AH Agents for dermatitis, excluding corticosteroids 0,0064 D11AH01 Tacrolimus(C) 56700 g D11AH02 Pimecrolimus(C) 196500 g D11AH05 Dupilumab(P) 66 g 21,4 mg 0,0064 D11AX Other dermatologicals 0,0624 D11AX01 Minoxidil(C) 93600 ml D11AX10 Finasteride(O) 30,156 g 0,001 g 0,0624 D11AX16 Eflornithine(C) 210 g D11AX22 Ivermectin(C) 71700 g D11AX82 Hydroquinone+Fluocinolone acetonide+Tretinoin(C) 30 g G GENITO URINARY SYSTEM AND SEX HORMONES 56,5981 G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS 0,9380
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
0,9380
G01AA Antibiotics 0,1489 G01AA10 Clindamycin(V) 7200,7 g 0,1 g 0,1489 G01AA80 Nystatin+Neomycin+Polymyxin B(V) 60 pieces G01AC Quinoline derivatives 0,0431 G01AC05 Dequalinium(V) 417,3 g 20 mg 0,0431 G01AF Imidazole derivatives 0,7460 G01AF01 Metronidazole (V) 12514 g 0,5 g 0,0518 G01AF02 Clotrimazole(V) 28968,8 g 0,1 g 0,5990 G01AF05 Econazole(V) 4606,2 g 0,1 g 0,0952 G02 OTHER GYNECOLOGICALS 4,3078 G02A UTEROTONICS 0,0956 G02AB Ergot alkaloids 0,0018 G02AB01 Methylergometrine(P) 0,1738 g 0,2 mg 0,0018 G02AD Prostaglandins 0,0938 G02AD02 Dinoprostone(P) 0,46 g G02AD02 Dinoprostone(V) 2,0649 g 0,5 mg 0,0085 G02AD06 Misoprostol(O) 8,2488 g 0,2 mg 0,0853 G02B CONTRACEPTIVES FOR TOPICAL USE 2,6245 G02BA Intrauterine contraceptives 0,0190 G02BA03 Levonorgestrel(V) 9176 pieces 1 pieces 0,0190 G02BB Intravaginal contraceptives 2,6055 G02BB01 Etonogestrel+Ethinylestradiol(V) 44021 pieces 0,036 pieces 2,5284 G02BB81 Benzalkonium chloride(V) 37300 pieces 1 pieces 0,0771 G02BB81 Benzalkonium chloride(V) 48240 g G02C OTHER GYNECOLOGICALS 1,5877 G02CA Sympathomimetics, labour repressants G02CA80 Hexoprenaline(P) 0,0222 g
15/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day G02CB Prolactine inhibitors 0,1534 G02CB01 Bromocriptine(O) 308,05 g 0,005 g 0,1274 G02CB03 Cabergoline(O) 6,3 g 0,5 mg 0,0261 G02CX Other gynecologicals 1,4342 G02CX01 Atosiban(P) 0,9375 g 0,165 g <0,0001 G02CX03 Agni casti fructus(O) 396270 pieces 1 pieces 0,8194 G02CX04 Cimicifugae rhizoma(O) 594690 pieces 2 pieces 0,6148
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM 31,9661
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE 25,5811 G03AA Progestogens and estrogens, fixed combinations 20,5113 G03AA07 Levonorgestrel+Ethinylestradiol(O) 174027 pieces 1 pieces 0,3598 G03AA09 Desogestrel+Ethinylestradiol(O) 471996 pieces 0,75 pieces 1,3013 G03AA10 Gestodene+Ethinylestradiol(O) 24164 pieces 1 pieces 0,0500 G03AA10 Gestodene+Ethinylestradiol(O) 2257689 pieces 0,75 pieces 6,2244 G03AA12 Drospirenone+Ethinylestradiol(O) 1144052 pieces 1 pieces 2,3656 G03AA12 Drospirenone+Ethinylestradiol(O) 1887102 pieces 0,75 pieces 5,2027 G03AA13 Norelgestromin+Ethinylestradiol(TD) 93681 pieces 0,107 pieces 1,8103 G03AA15 Chlormadinone+Ethinylestradiol(O) 184716 pieces 0,75 pieces 0,5093 G03AA16 Dienogest+Ethinylestradiol(O) 361200 pieces 1 pieces 0,7469 G03AA16 Dienogest+Ethinylestradiol(O) 704109 pieces 0,75 pieces 1,9412 G03AB Progestogens and estrogens, sequential preparations 0,1749 G03AB05 Desogestrel+Ethinylestradiol(O) 4092 pieces 0,75 pieces 0,0113 G03AB08 Dienogest+Estradiol valerate(O) 79128 pieces 1 pieces 0,1636 G03AC Progestogens 4,8117 G03AC08 Etonogestrel(P) 66,572 g 68 mcg 2,0243 G03AC09 Desogestrel(O) 1348060 pieces 1 pieces 2,7874 G03AD Emergency contraceptives 0,0832 G03AD01 Levonorgestrel(O) 58,026 g 1,5 mg 0,0800 G03AD02 Ulipristal(O) 46,65 g 0,03 g 0,0032 G03B ANDROGENS 0,2302 G03BA 3-oxoandrosten (4) derivatives 0,2302 G03BA03 Testosterone(C) 22,5 g 0,05 g 0,0009 G03BA03 Testosterone(O) 7,2 g 0,12 g 0,0001 G03BA03 Testosterone(P) 1994,25 g 0,018 g 0,2291 G03BA03 Testosterone(TD) 2,576 g 0,05 g 0,0001 G03C ESTROGENS 1,6383 G03CA Natural and semisynthetic estrogens, plain 1,6328 G03CA03 Estradiol(C, V) 106075 g G03CA03 Estradiol(O) 774,816 g 2 mg 0,8011 G03CA03 Estradiol(TD) 0,0336 g 0,05 mg 0,0014 G03CA03 Estradiol(TD) 21,3343 g 1,53 mg 0,0288 G03CA03 Estradiol(TD) 68,8835 g 1 mg 0,1424 G03CA03 Estradiol(V) 5,3221 g 0,025 mg 0,4402 G03CA04 Estriol(O) 0,45 g 0,002 g 0,0005 G03CA04 Estriol(V) 21,1275 g 0,2 mg 0,2184 G03CA80 Estradiol+Prednisolone(C) 77725 g G03CX Other estrogens 0,0055 G03CX01 Tibolone(O) 6,65 g 2,5 mg 0,0055 G03D PROGESTOGENS 1,4796 G03DA Pregnen (4) derivatives 0,6687 G03DA02 Medroxyprogesterone(O) 46,05 g 0,005 g 0,0190 G03DA02 Medroxyprogesterone(P) 266,055 g 0,007 g 0,0786 G03DA04 Progesterone(O) 30234 g 0,3 g 0,2084 G03DA04 Progesterone(P) 201,225 g 0,005 g 0,0832 G03DA04 Progesterone(V) 12163,95 g 0,09 g 0,2795 G03DB Pregnadien derivatives 0,8109 G03DB01 Dydrogesterone(O) 3106,6 g 0,01 g 0,6424 G03DB08 Dienogest(O) 163,016 g 2 mg 0,1685 G03F PROGESTOGENS AND ESTROGENS IN COMBINATION 2,1512
16/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day G03FA Progestogens and estrogens, fixed combinations 1,6917 G03FA01 Norethisterone+Estradiol(O) 526260 pieces 1 pieces 1,0882 G03FA14 Dydrogesterone+Estradiol(O) 116452 pieces 1 pieces 0,2408 G03FA17 Drospirenone+Estradiol(O) 175420 pieces 1 pieces 0,3627 G03FA80 Medroxyprogesterone+Estradiol(O) 168 pieces G03FB Progestogens and estrogens, sequential preparations 0,4595 G03FB05 Norethisterone+Estradiol(O) 174916 pieces 1 pieces 0,3617 G03FB08 Dydrogesterone+Estradiol(O) 47320 pieces 1 pieces 0,0978 G03G GONADOTROPINS AND OTHER OVULATION STIMULANTS 0,3838 G03GA Gonadotropins 0,1569 G03GA01 Chorionic gonadotrophin(P) 40000 U 250 U 0,0003 G03GA05 Follitropin alfa(P) 4909125 U 75 U 0,1353 G03GA07 Lutropin alfa(P) 384075 U 75 U 0,0106 G03GA08 Choriogonadotropin alfa(P) 0,9128 g 0,25 mg 0,0075 G03GA30 Follitropin alfa+Lutropin alfa(P) 1490 doses 1 doses 0,0031 G03GB Ovulation stimulants, synthetic 0,2269 G03GB02 Clomifene(O) 987,7 g 0,009 g 0,2269 G03H ANTIANDROGENS 0,4714 G03HA Antiandrogens, plain 0,1183 G03HA01 Cyproterone(O) 5722,5 g 0,1 g 0,1183 G03HB Antiandrogens and estrogens 0,3531 G03HB01 Cyproterone+Estrogen(O) 128058 pieces 0,75 pieces 0,3531
G03X OTHER SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
0,0305
G03XA Antigonadotropins and similar agents 0,0008 G03XA01 Danazol(O) 240 g 0,6 g 0,0008 G03XB Progesterone receptor modulators 0,0296 G03XB01 Mifepristone(O) 803,4 g 0,6 g 0,0028 G03XB02 Ulipristal(O) 64,96 g 5 mg 0,0269 G04 UROLOGICALS 19,3862 G04B UROLOGICALS 3,1912 G04BD Drugs for urinary frequency and incontinence 1,8302 G04BD04 Oxybutynin(O) 4754,4 g 0,015 g 0,6554 G04BD06 Propiverine(O) 8,82 g 0,03 g 0,0006 G04BD07 Tolterodine(O) 519,736 g 0,004 g 0,2687 G04BD08 Solifenacin(O) 588,6 g 0,005 g 0,2434 G04BD09 Trospium chloride(O) 3496,95 g 0,04 g 0,1808 G04BD12 Mirabegron(O) 11640 g 50 mg 0,4814 G04BE Drugs used in erectile dysfunction 1,3477 G04BE01 Alprostadil(P) 0,0722 g 0,02 mg 0,0075 G04BE01 Alprostadil(urethral) 0,006 g 0,25 mg <0,0001 G04BE03 Sildenafil(O) 24328 g 0,05 g 1,0061 G04BE08 Tadalafil(O) 1339,24 g 0,01 g 0,2769 G04BE09 Vardenafil(O) 30,72 g 0,01 g 0,0064 G04BE10 Avanafil(O) 2460 g 0,1 g 0,0509 G04BX Other urologicals 0,0133 G04BX14 Dapoxetin(O) 192,87 g 0,03 g 0,0133 G04BX80 Centaury+Lovage root+Rosemary leaf(O) 1028220 pieces G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY 16,1950 G04CA Alpha-adrenoreceptor antagonists 13,3268 G04CA01 Alfuzosin(O) 8090,4 g 7,5 mg 2,2305 G04CA02 Tamsulosin(O) 1511,76 g 0,4 mg 7,8147 G04CA04 Silodosin(O) 573,12 g 8 mg 0,1481 G04CA52 Tamsulosin+Dutasteride(O) 1515420 pieces 1 pieces 3,1335 G04CB Testosterone-5-alpha reductase inhibitors 0,5733 G04CB01 Finasteride(O) 341,05 g 0,005 g 0,1410 G04CB02 Dutasteride(O) 104,535 g 0,5 mg 0,4323 G04CX Other drugs used in benign prostatic hypertrophy 2,2949 G04CX02 Sabalis serrulatae fructus(O) 355152 g 0,32 g 2,2949
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
29,7102
H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES 0,4330
H01A ANTERIOR PITUITARY LOBE HORMONES AND ANALOGUES 0,1540 H01AA ACTH 0,0001 H01AA02 Tetracosactide(P) 0,0107 g 0,25 mg 0,0001 H01AB Thyrotropin 0,0007 H01AB01 Thyrotropin alfa(P) 0,3078 g 0,9 mg 0,0007 H01AC Somatropin and somatropin agonists 0,1364 H01AC01 Somatropin(P) 131899,5347 U 2 U 0,1364 H01AX Other anterior pituitary lobe hormones and analogues 0,0168 H01AX01 Pegvisomant(P) 81,3 g 0,01 g 0,0168 H01B POSTERIOR PITUITARY LOBE HORMONES 0,1520 H01BA Vasopressin and analogues 0,0949 H01BA01 Argipressin(P) 12600 U 40 U 0,0007 H01BA02 Desmopressin(N) 0,0383 g 0,025 mg 0,0032 H01BA02 Desmopressin(P) 0,0191 g 0,004 mg 0,0098 H01BA02 Desmopressin(SL) 9,4284 g 0,24 mg 0,0812 H01BB Oxytocin and analogues 0,0571 H01BB01 Demoxytocin(O) 1206500 U 100 U 0,0249 H01BB02 Oxytocin(P) 227900 U 15 U 0,0314 H01BB03 Carbetocin(P) 0,0348 g 0,1 mg 0,0007 H01C HYPOTHALAMIC HORMONES 0,1271 H01CA Gonadotropin-releasing hormones H01CA01 Gonadorelin(P) 0,0041 g H01CB Somatostatin and analogues 0,1057 H01CB02 Octreotide(P) 13,1715 g 0,7 mg 0,0389 H01CB03 Lanreotide(P) 84,18 g 3 mg 0,0580 H01CB05 Pasireotide(P) 5,07 g 1,2 mg 0,0087 H01CC Anti-gonadotropin-releasing hormones 0,0214 H01CC02 Cetrorelix(P) 2,5893 g 0,25 mg 0,0214 H02 CORTICOSTEROIDS FOR SYSTEMIC USE 8,7530 H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN 8,7469 H02AA Mineralocorticoids 0,1618 H02AA02 Fludrocortisone(O) 7,825 g 0,1 mg 0,1618 H02AB Glucocorticoids 8,5851 H02AB01 Betamethasone(P) 18,488 g 1,5 mg 0,0255 H02AB02 Dexamethasone(O) 833,815 g 1,5 mg 1,1494 H02AB02 Dexamethasone(P) 743,1 g 1,5 mg 1,0243 H02AB04 Methylprednisolone(O) 7413,2 g 7,5 mg 2,0438 H02AB04 Methylprednisolone(P) 5143,765 g 0,02 g 0,5318 H02AB06 Prednisolone(O) 12503 g 0,01 g 2,5853 H02AB06 Prednisolone(P) 2400,45 g 0,01 g 0,4963 H02AB08 Triamcinolone(O) 13,4 g 7,5 mg 0,0037 H02AB08 Triamcinolone(P) 1572,9 g 7,5 mg 0,4336 H02AB09 Hydrocortisone(O) 3511,15 g 0,03 g 0,2420 H02AB09 Hydrocortisone(P) 716,2 g 0,03 g 0,0494 H02B CORTICOSTEROIDS FOR SYSTEMIC USE, COMBINATIONS 0,0060 H02BX Corticosteroids for systemic use, combinations 0,0060 H02BX80 Hydrocortisone+Lidocaine(P) 87,5 g 0,03 g 0,0060 H03 THYROID THERAPY 20,4827 H03A THYROID PREPARATIONS 19,1590 H03AA Thyroid hormones 19,1590 H03AA01 Levothyroxine sodium(O) 1389,735 g 0,15 mg 19,1572 H03AA02 Liothyronine(O) 0,0528 g 0,06 mg 0,0018 H03AA03 Levothyroxine sodium+Liothyronine(O) 1500 pieces H03AA04 Tiratricol(O) 0,63 g H03B ANTITHYROID PREPARATIONS 1,3237 H03BA Thiouracils 0,1460
18/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day H03BA02 Propylthiouracil(O) 7061,8 g 0,1 g 0,1460 H03BB Sulfur-containing imidazole derivatives 1,1777 H03BB02 Thiamazole(O) 5695,5 g 0,01 g 1,1777 H03BC Perchlorates H03BC02 Sodium perchlorate(O) 24 g H04 PANCREATIC HORMONES 0,0011 H04A GLYCOGENOLYTIC HORMONES 0,0011 H04AA Glycogenolytic hormones 0,0011 H04AA01 Glucagon(P) 0,53 g 0,001 g 0,0011 H05 CALCIUM HOMEOSTASIS 0,0404 H05B ANTI-PARATHYROID AGENTS 0,0404 H05BX Other anti-parathyroid agents 0,0404 H05BX01 Cinacalcet(O) 949,2 g 0,06 g 0,0327 H05BX02 Paricalcitol(O) 0,0074 g 2 mcg 0,0077 J ANTIINFECTIVES FOR SYSTEMIC USE 19,2087 J01 ANTIBACTERIALS FOR SYSTEMIC USE 11,9736 J01A TETRACYCLINES 1,3846 J01AA Tetracyclines 1,3846 J01AA02 Doxycycline(O) 66939 g 0,1 g 1,3841 J01AA08 Minocycline(O) 7,5 g 0,2 g 0,0001 J01AA12 Tigecycline(P) 20 g 0,1 g 0,0004 J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS 4,2870 J01CA Penicillins with extended spectrum 1,6833 J01CA01 Ampicillin(P) 23700 g 6 g 0,0082 J01CA04 Amoxicillin(O) 1215205 g 1,5 g 1,6751 J01CE Beta-lactamase sensitive penicillins 0,1596 J01CE01 Benzylpenicillin(P) 34860 g 3,6 g 0,0200 J01CE02 Phenoxymethylpenicillin(O) 133958,4 g 2 g 0,1385 J01CE08 Benzathine benzylpenicillin(P) 1803,6 g 3,6 g 0,0010 J01CE80 Benzathine benzylpenicillin+Procaine benzylpenicillin(P) 34,2 g 3,6 g <0,0001 J01CF Beta-lactamase resistant penicillins 0,0976 J01CF04 Oxacillin(P) 94300 g 2 g 0,0975 J01CF05 Flucloxacillin(O) 140 g 2 g 0,0001 J01CR Combinations of penicillins, incl. beta-lactamase inhibitors 2,3465 J01CR01 Ampicillin+Sulbactam(P) 125827 g 6 g 0,0434 J01CR02 Amoxicillin+Clavulanic acid(O) 1464285,55 g 1,5 g 2,0185 J01CR02 Amoxicillin+Clavulanic acid(P) 241480 g 3 g 0,1664 J01CR04 Sultamicillin(O) 56457 g 1,5 g 0,0778 J01CR05 Piperacillin+Tazobactam(P) 273328 g 14 g 0,0404 J01D OTHER BETA-LACTAM ANTIBACTERIALS 1,6932 J01DB First-generation cephalosporins 0,2473 J01DB01 Cefalexin(O) 60 g 2 g 0,0001 J01DB04 Cefazolin(P) 105710 g 3 g 0,0729 J01DB05 Cefadroxil(O) 168641 g 2 g 0,1744 J01DC Second-generation cephalosporins 1,3172 J01DC01 Cefoxitin(P) 10452 g 6 g 0,0036 J01DC02 Cefuroxime(O) 257183 g 0,5 g 1,0636 J01DC02 Cefuroxime(P) 283935 g 3 g 0,1957 J01DC10 Cefprozil(O) 26277 g 1 g 0,0543 J01DD Third-generation cephalosporins 0,0523 J01DD01 Cefotaxime(P) 46930 g 4 g 0,0243 J01DD02 Ceftazidime(P) 13712 g 4 g 0,0071 J01DD04 Ceftriaxone(P) 19600 g 2 g 0,0203 J01DD81 Ceftazidime+Avibactam(P) 2120 g 6 g 0,0007 J01DE Fourth-generation cephalosporins 0,0101 J01DE01 Cefepime(P) 19630 g 4 g 0,0101 J01DH Carbapenems 0,0662 J01DH02 Meropenem(P) 45205 g 3 g 0,0312 J01DH03 Ertapenem(P) 10333 g 1 g 0,0214 J01DH51 Imipenem+Cilastatin(P) 13210 g 2 g 0,0137
19/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day J01DI Other cephalosporins and penems <0,0001 J01DI54 Ceftolozane+Tazobactam(P) 60 g 3 g <0,0001 J01E SULFONAMIDES AND TRIMETHOPRIM 0,4532 J01EA Trimethoprim and derivatives 0,0229 J01EA01 Trimethoprim(O) 4431 g 0,4 g 0,0229
J01EE Combinations of sulfonamides and trimethoprim, incl. derivatives 0,4303
J01EE01 Sulfamethoxazole+Trimethoprim(O) 400 pieces 4 pieces 0,0002 J01EE01 Sulfamethoxazole+Trimethoprim(O) 374500 pieces 2 pieces 0,3872 J01EE01 Sulfamethoxazole+Trimethoprim(O) 719100 ml 40 ml 0,0372 J01EE01 Sulfamethoxazole+Trimethoprim(P) 55570 ml 20 ml 0,0057 J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS 2,4893 J01FA Macrolides 2,3132 J01FA01 Erythromycin(O) 50 g 1 g 0,0001 J01FA01 Erythromycin(P) 130 g 1 g 0,0003 J01FA09 Clarithromycin(O) 417627 g 0,5 g 1,7271 J01FA09 Clarithromycin(P) 3239,5 g 1 g 0,0067 J01FA10 Azithromycin(O) 84004,4 g 0,3 g 0,5790 J01FA10 Azithromycin(P) 7 g 0,5 g <0,0001 J01FF Lincosamides 0,1761 J01FF01 Clindamycin(O) 95548,8 g 1,2 g 0,1646 J01FF01 Clindamycin(P) 10005 g 1,8 g 0,0115 J01G AMINOGLYCOSIDE ANTIBACTERIALS 0,0241 J01GB Other aminoglycosides 0,0241 J01GB01 Tobramycin(I) 100,352 g 0,112 g 0,0019 J01GB01 Tobramycin(I) 470,4 g 0,3 g 0,0032 J01GB03 Gentamicin(P) 1631,025 g 0,24 g 0,0141 J01GB06 Amikacin(P) 2415 g 1 g 0,0050 J01M QUINOLONE ANTIBACTERIALS 0,7739 J01MA Fluoroquinolones 0,7739 J01MA01 Ofloxacin(O) 3308 g 0,4 g 0,0171 J01MA02 Ciprofloxacin(O) 267965 g 1 g 0,5541 J01MA02 Ciprofloxacin(P) 12164,5 g 0,8 g 0,0314 J01MA06 Norfloxacin(O) 46536 g 0,8 g 0,1203 J01MA12 Levofloxacin(O) 3202,5 g 0,5 g 0,0132 J01MA12 Levofloxacin(P) 385 g 0,5 g 0,0016 J01MA14 Moxifloxacin(O) 6818 g 0,4 g 0,0352 J01MA14 Moxifloxacin(P) 184 g 0,4 g 0,0010 J01X OTHER ANTIBACTERIALS 0,8682 J01XA Glycopeptide antibacterials 0,0229 J01XA01 Vancomycin(P) 22075 g 2 g 0,0228 J01XA02 Teicoplanin(P) 13,6 g 0,4 g 0,0001 J01XB Polymyxins 0,0019 J01XB01 Colistin(I, P) 1740000000 U 9000000 U 0,0004 J01XB01 Colistin(P) 6430000000 U 9000000 U 0,0015 J01XC Steroid antibacterials 0,0002 J01XC01 Fusidic acid(O) 150 g 1,5 g 0,0002 J01XD Imidazole derivatives 0,2389 J01XD01 Metronidazole (O) 193175 g 2 g 0,1997 J01XD01 Metronidazole (P) 28415 g 1,5 g 0,0392 J01XE Nitrofuran derivatives 0,5830 J01XE01 Nitrofurantoin(O) 56394 g 0,2 g 0,5830 J01XX Other antibacterials 0,0213 J01XX01 Fosfomycin(O) 4881 g 3 g 0,0034 J01XX08 Linezolid(O) 8862 g 1,2 g 0,0153 J01XX08 Linezolid(P) 1482 g 1,2 g 0,0026 J01XX09 Daptomycin(P) 21 g 0,28 g 0,0002 J02 ANTIMYCOTICS FOR SYSTEMIC USE 0,3666 J02A ANTIMYCOTICS FOR SYSTEMIC USE 0,3666 J02AA Antibiotics 0,0089
20/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day J02AA01 Amphotericin(O) 315 g J02AA01 Amphotericin(P) 151,35 g 0,035 g 0,0089 J02AB Imidazole derivatives 0,0002 J02AB02 Ketoconazole(O) 20 g 0,2 g 0,0002 J02AC Triazole derivatives 0,3493 J02AC01 Fluconazole(O) 12330,4 g 0,2 g 0,1275 J02AC01 Fluconazole(P) 3068,6 g 0,2 g 0,0317 J02AC02 Itraconazole(O) 15006,2 g 0,2 g 0,1551 J02AC03 Voriconazole(O) 2446,4 g 0,4 g 0,0126 J02AC03 Voriconazole(P) 212,8 g 0,4 g 0,0011 J02AC04 Posaconazole(O) 2971,2 g 0,3 g 0,0205 J02AC05 Isavuconazole(O) 39,2 g 0,2 g 0,0004 J02AC05 Isavuconazole(P) 30,4 g 0,2 g 0,0003 J02AX Other antimycotics for systemic use 0,0081 J02AX04 Caspofungin(P) 76,95 g 0,05 g 0,0032 J02AX06 Anidulafungin(P) 240,1 g 0,1 g 0,0050 J04 ANTIMYCOBACTERIALS 0,1140 J04A DRUGS FOR TREATMENT OF TUBERCULOSIS 0,0943 J04AB Antibiotics 0,0302 J04AB01 Cycloserine(O) 7000 g 0,75 g 0,0193 J04AB02 Rifampicin(O) 3090 g 0,6 g 0,0106 J04AB02 Rifampicin(P) 84 g 0,6 g 0,0003 J04AC Hydrazides 0,0031 J04AC01 Isoniazid(O) 450 g 0,3 g 0,0031 J04AD Thiocarbamide derivatives 0,0110 J04AD01 Protionamide(O) 4000 g 0,75 g 0,0110 J04AK Other drugs for treatment of tuberculosis 0,0096 J04AK03 Terizidone(O) 137,5 g J04AK05 Bedaquiline(O) 225,6 g 86 mg 0,0054 J04AK06 Delamanid(O) 408 g 0,2 g 0,0042 J04AM Combinations of drugs for treatment of tuberculosis 0,0403 J04AM02 Rifampicin+Isoniazid(O) 12000 pieces 4 pieces 0,0062 J04AM02 Rifampicin+Isoniazid(O) 33000 pieces 2 pieces 0,0341 J04B DRUGS FOR TREATMENT OF LEPRA 0,0196 J04BA Drugs for treatment of lepra 0,0196 J04BA01 Clofazimine(O) 380 g 0,1 g 0,0079 J04BA02 Dapsone(O) 285 g 0,05 g 0,0118 J05 ANTIVIRALS FOR SYSTEMIC USE 6,7546 J05A DIRECT ACTING ANTIVIRALS 6,7546
J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors 0,3683
J05AB01 Aciclovir(O) 317568,62 g 4 g 0,1642 J05AB01 Aciclovir(P) 2950 g 4 g 0,0015 J05AB06 Ganciclovir(P) 196 g 0,5 g 0,0008 J05AB11 Valaciclovir(O) 277732 g 3 g 0,1914 J05AB14 Valganciclovir(O) 4537 g 0,9 g 0,0104 J05AD Phosphonic acid derivatives 0,0011 J05AD01 Foscarnet sodium(P) 3420 g 6,5 g 0,0011 J05AF Nucleoside and nucleotide reverse transcriptase inhibitors 0,1005 J05AF01 Zidovudine(O) 356 g 0,6 g 0,0012 J05AF01 Zidovudine(P) 25 g 0,6 g 0,0001 J05AF05 Lamivudine(O) 1210 g 0,3 g 0,0083 J05AF06 Abacavir(O) 1850,4 g 0,6 g 0,0064 J05AF07 Tenofovir disoproxil(O) 58,8 g 0,245 g 0,0005 J05AF10 Entecavir(O) 19,875 g 0,5 mg 0,0822 J05AF13 Tenofovir alafenamide(O) 21 g 25 mg 0,0017 J05AG Non-nucleoside reverse transcriptase inhibitors 0,9683 J05AG03 Efavirenz(O) 76320 g 0,6 g 0,2630 J05AG05 Rilpivirine(O) 8527,5 g 25 mg 0,7053 J05AH Neuraminidase inhibitors 0,2697
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day J05AH02 Oseltamivir(O) 19565,25 g 0,15 g 0,2697 J05AP Antivirals for treatment of HCV infections 0,1316 J05AP01 Ribavirin(O) 1013,6 g 1 g 0,0021 J05AP54 Elbasvir+Grazoprevir(O) 5208 pieces 1 pieces 0,0108 J05AP55 Sofosbuvir+Velpatasvir(O) 6188 pieces 1 pieces 0,0128 J05AP57 Glecaprevir+Pibrentasvir(O) 153720 pieces 3 pieces 0,1059 J05AR Antivirals for treatment of HIV infections, combinations 3,9775 J05AR01 Zidovudine+Lamivudine(O) 128640 pieces 2 pieces 0,1330 J05AR02 Lamivudine+Abacavir(O) 367740 pieces 1 pieces 0,7604 J05AR03 Tenofovir disoproxil+Emtricitabine(O) 783120 pieces 1 pieces 1,6193 J05AR09 Elvitegravir+Cobicistat+Emtricitabine+Tenofovir disoproxil(O) 6120 pieces 1 pieces 0,0127 J05AR13 Lamivudine+Abacavir+Dolutegravir(O) 183990 pieces 1 pieces 0,3804 J05AR14 Darunavir+Cobicistat(O) 517620 pieces 1 pieces 1,0703
J05AR18 Emtricitabine+Tenofovir alafenamide+Elvitegravir+Cobicistat(O) 720 pieces 1 pieces 0,0015
J05AX Other antivirals 0,9376 J05AX08 Raltegravir(O) 342474 g 0,8 g 0,8852 J05AX12 Dolutegravir(O) 1267,05 g 50 mg 0,0524 J06 IMMUNE SERA AND IMMUNOGLOBULINS J06A IMMUNE SERA J06AA Immune sera J06AA03 Snake venom antiserum(P) 20 pieces J06B IMMUNOGLOBULINS J06BA Immunoglobulins, normal human J06BA01 Immunoglobulins, normal human, for extravascular a(P) 10863,6 g J06BA02 Immunoglobulins, normal human, for intravascular a(P) 107765 g J06BA80 Human normal immunoglobulin(P) 500 g J06BB Specific immunoglobulins J06BB01 Human Anti-D Immunoglobulin(P) 2385000 U J06BB02 Tetanus immunoglobulin(P) 25000 U J06BB03 Varicella zoster immunoglobulin(P) 4375 U J06BB04 Hepatitis B immunoglobulin(P) 2560 U J06BB05 Rabies immunoglobulin(P) 3000 U J06BB09 Cytomegalovirus immunoglobulin(P) 70000 U J06BB16 Palivizumab(P) 60,1 g J07 VACCINES J07A BACTERIAL VACCINES J07AE Cholera vaccines J07AE01 Cholera, inactivated, whole cell(O) 20 doses J07AG Hemophilus influenzae B vaccines J07AG01 Haemophilus influenzae B, purified antigen conjugated(P) 190 doses J07AH Meningococcal vaccines
J07AH08 Meningococcus, tetravalent purified polysaccharides antigen conjugated(P)
520 doses
J07AH09 Meningococcus B, multicomponent vaccine(P) 163 doses J07AL Pneumococcal vaccines J07AL01 Pneumococcus, purified polysaccharides antigen(P) 337 doses
J07AL02 Pneumococcus, purified polysaccharides antigen conjugated(P) 2523 doses
J07AL52 Pneumococcus, purified polysaccharides antigen+Haemophilus influenzae, conjugated(P)
232 doses
J07AM Tetanus vaccines J07AM51 Tetanus toxoid+Diphtheria toxoid(P) 28872 doses J07AN Tuberculosis vaccines J07AN01 Tuberculosis, live attenuated(P) 23950 doses J07AP Typhoid vaccines J07AP03 Typhoid, purified polysaccharide antigen(P) 2112 doses J07AX Other bacterial vaccines J07AX80 Diphtheria-tetanus-pertussis(P) 18985 doses J07B VIRAL VACCINES
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day J07BA Encephalitis vaccines J07BA01 Encephalitis, tick borne, inactivated, whole virus(P) 120044 doses J07BB Influenza vaccines J07BB02 Influenza, inactivated, split virus or surface antigen(P) 167327 doses J07BC Hepatitis vaccines J07BC01 Hepatitis B, purified antigen(P) 4390 doses J07BC02 Hepatitis A, inactivated, whole virus(P) 8119 doses
J07BC80 Hepatitis A, inactivated, whole virus+Hepatitis B, purified antigen(P) 3039 doses
J07BD Measles vaccines
J07BD52 Measles, live attunated+Rubella, live attenuated+Mumps, live,attenuated(P)
49093 doses
J07BF Poliomyelitis vaccines J07BF03 Poliomyelitis, trivalent, inactivated, whole virus(P) 672 doses J07BG Rabies vaccines J07BG01 Rabies, inactivated, whole virus(P) 2446 doses J07BH Rota virus diarrhea vaccines J07BH02 Rota virus, pentavalent, live, reassorted(O) 65364 doses J07BK Varicella zoster vaccines J07BK01 Varicella, live attenuated(P) 1338 doses J07BK02 Zoster, live attenuated(P) 55 doses J07BK03 Zoster, purified antigen(P) 2 doses J07BL Yellow fever vaccines J07BL01 Yellow fever, live attenuated(P) 1836 doses J07BM Papillomavirus vaccines J07BM02 Papillomavirus (human types 16, 18)(P) 26 doses
J07BM03 Papillomavirus (human types 6, 11, 16, 18, 31, 33, 45, 52, 58)(P) 15253 doses
J07C BACTERIAL AND VIRAL VACCINES, COMBINED J07CA Bacterial and viral vaccines, combined
J07CA02 Diphtheria toxoid+Pertussis, purified antigen+Tetanus toxoid+Poliomyelitis, trivalent, inactivated, whole virus(P)
16251 doses
J07CA06 Diphtheria toxoid+Tetanus toxoid+Pertussis, purified antigen+Poliomyelitis, trivalent, inactivated, whole virus+Haemophilus influenzae B, purified antigen conjugated(P)
11167 doses
J07CA09 Diphtheria toxoid+Poliomyelitis, trivalent, inactivated, whole virus+Pertussis, purified antigen+Haemophilus influenzae B, purified antigen conjugated+Hepatitis B, purified antigen+Tetanus toxoid(P)
39406 doses
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS 11,8547 L01 ANTINEOPLASTIC AGENTS L01A ALKYLATING AGENTS L01AA Nitrogen mustard analogues L01AA01 Cyclophosphamide(O) 757,5 g L01AA01 Cyclophosphamide(P) 3928 g L01AA02 Chlorambucil(O) 23 g L01AA03 Melphalan(O) 8,4 g L01AA03 Melphalan(P) 30,8 g L01AA06 Ifosfamide(P) 2477 g L01AA07 Trofosfamide(O) 15 g L01AA09 Bendamustine(P) 267,55 g L01AB Alkyl sulfonates L01AB01 Busulfan(O) 5,2 g L01AB01 Busulfan(P) 9,6 g L01AB02 Treosulfan(P) 625 g L01AC Ethylene imines L01AC01 Thiotepa(P) 5,78 g L01AD Nitrosoureas L01AD01 Carmustine(P) 7,7 g
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day L01AD02 Lomustine(O) 28,6 g L01AX Other alkylating agents L01AX03 Temozolomide(O) 753,6 g L01AX04 Dacarbazine(P) 470 g L01B ANTIMETABOLITES L01BA Folic acid analogues L01BA01 Methotrexate(P) 1737,05 g L01BA04 Pemetrexed(P) 233 g L01BB Purine analogues L01BB02 Mercaptopurine(O) 346,75 g L01BB03 Tioguanine(O) 10 g L01BB04 Cladribine(P) 0,26 g L01BB05 Fludarabine(P) 19,5 g L01BB07 Nelarabine(P) 10,5 g L01BC Pyrimidine analogues L01BC01 Cytarabine(P) 2276,5 g L01BC02 Fluorouracil(P) 18445 g L01BC05 Gemcitabine(P) 5022,0536 g L01BC06 Capecitabine(O) 259620 g L01BC07 Azacitidine(P) 184,1 g L01BC83 Trifluridine+Tipiracil(O) 7760 pieces L01C PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS L01CA Vinca alkaloids and analogues L01CA01 Vinblastine(P) 3,18 g L01CA02 Vincristine(P) 2,29 g L01CA04 Vinorelbine(O) 2,3 g L01CA04 Vinorelbine(P) 17,95 g L01CB Podophyllotoxin derivatives L01CB01 Etoposide(O) 235 g L01CB01 Etoposide(P) 509,9 g L01CD Taxanes L01CD01 Paclitaxel(P) 763,3 g L01CD02 Docetaxel(P) 443,52 g L01CD04 Cabazitaxel(P) 1,44 g L01D CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES L01DA Actinomycines L01DA01 Dactinomycin(P) 0,0425 g L01DB Anthracyclines and related substances L01DB01 Doxorubicin(P) 130,1 g L01DB02 Daunorubicin(P) 8,22 g L01DB03 Epirubicin(P) 253,9 g L01DB06 Idarubicin(O) 0,09 g L01DB06 Idarubicin(P) 1,41 g L01DB07 Mitoxantrone(P) 2,46 g L01DB11 Pixantrone(P) 0,783 g L01DC Other cytotoxic antibiotics L01DC01 Bleomycin(P) 5175000 U L01DC03 Mitomycin(P) 6,2 g L01X OTHER ANTINEOPLASTIC AGENTS L01XA Platinum compounds L01XA01 Cisplatin(P) 228,3 g L01XA02 Carboplatin(P) 1941 g L01XA03 Oxaliplatin(P) 884,4 g L01XB Methylhydrazines L01XB01 Procarbazine(O) 152,5 g L01XC Monoclonal antibodies L01XC02 Rituximab(P) 2109,376 g L01XC03 Trastuzumab(P) 1724,55 g L01XC05 Gemtuzumab ozogamicin(P) 0,005 g L01XC06 Cetuximab(P) 132,5 g
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day L01XC07 Bevacizumab(P) 1134,4 g L01XC08 Panitumumab(P) 109,3 g L01XC11 Ipilimumab(P) 0,8 g L01XC12 Brentuximab vedotin(P) 11,5 g L01XC13 Pertuzumab(P) 122,64 g L01XC14 Trastuzumab emtansine(P) 35,74 g L01XC15 Obinutuzumab(P) 90 g L01XC17 Nivolumab(P) 147,18 g L01XC18 Pembrolizumab(P) 261,65 g L01XC19 Blinatumomab(P) 0,0014 g L01XC21 Ramucirumab(P) 2,1 g L01XC24 Daratumumab(P) 379,6 g L01XC26 Inotuzumab ozogamicin(P) 0,004 g L01XC28 Durvalumab(P) 342 g L01XC32 Atezolizumab(P) 31,2 g L01XD Sensitizers used in photodynamic/radiation therapy L01XD04 Aminolevulinic acid(O) 25,5 g L01XE Protein kinase inhibitors L01XE01 Imatinib(O) 14424 g L01XE02 Gefitinib(O) 1305 g L01XE03 Erlotinib(O) 156 g L01XE04 Sunitinib(O) 381,85 g L01XE05 Sorafenib(O) 3494,4 g L01XE06 Dasatinib(O) 660 g L01XE07 Lapatinib(O) 175 g L01XE08 Nilotinib(O) 6630,4 g L01XE09 Temsirolimus(P) 0,39 g L01XE10 Everolimus(O) 34,65 g L01XE11 Pazopanib(O) 15228 g L01XE13 Afatinib(O) 95,48 g L01XE14 Bosutinib(O) 319,2 g L01XE16 Crizotinib(O) 720 g L01XE17 Axitinib(O) 55,776 g L01XE18 Ruxolitinib(O) 249,2 g L01XE21 regorafenib(O) 342,72 g L01XE23 Dabrafenib(O) 3753 g L01XE24 Ponatinib(O) 2,7 g L01XE25 Trametinib(O) 26,37 g L01XE26 Cabozantinib(O) 324,44 g L01XE27 Ibrutinib(O) 5569,2 g L01XE28 Ceritinib(O) 112,5 g L01XE29 Lenvatinib(O) 3,6 g L01XE31 Nintedanib(O) 5775 g L01XE33 Palbociclib(O) 193,725 g L01XE35 Osimertinib(O) 160,8 g L01XE36 Alectinib(O) 67,2 g L01XE39 Midostaurin(O) 21 g L01XE42 Ribociclib(O) 1461,6 g L01XE43 Brigatinib(O) 181,08 g L01XE44 Lorlatinib(O) 6 g L01XX Other antineoplastic agents L01XX01 Amsacrine(P) 0,45 g L01XX02 Asparaginase(P) 1300000 U L01XX05 Hydroxycarbamide(O) 225350 g L01XX11 Estramustine(O) 193,2 g L01XX14 Tretinoin(O) 21 g L01XX17 Topotecan(P) 2,608 g L01XX19 Irinotecan(P) 729 g L01XX23 Mitotane(O) 1650 g L01XX24 Pegaspargase(P) 262500 U
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day L01XX27 Arsenic trioxide(P) 0,8 g L01XX32 Bortezomib(P) 8,9565 g L01XX35 Anagrelide(O) 2 g L01XX41 Eribulin(P) 0,1989 g L01XX42 Panobinostat(O) 0,48 g L01XX45 Carfilzomib(P) 2,76 g L01XX46 Olaparib(O) 5854,4 g L01XX47 Idelalisib(O) 27 g L01XX50 Ixazomib(O) 0,54 g L01XX52 Venetoclax(O) 31,36 g L01XX54 Niraparib(O) 14 g L02 ENDOCRINE THERAPY 4,6931 L02A HORMONES AND RELATED AGENTS 0,6059 L02AB Progestogens 0,0099 L02AB02 Medroxyprogesterone(O) 4785 g 1 g 0,0099 L02AE Gonadotropin releasing hormone analogues 0,5960 L02AE01 Buserelin(N) 1,95 g 1,2 mg 0,0034 L02AE03 Goserelin(P) 8,4276 g 0,129 mg 0,1351 L02AE04 Triptorelin(P) 0,2366 g 0,1 mg 0,0049 L02AE04 Triptorelin(P) 29,3325 g 0,134 mg 0,4526 L02B HORMONE ANTAGONISTS AND RELATED AGENTS 4,0873 L02BA Anti-estrogens 0,7950 L02BA01 Tamoxifen(O) 5953,8 g 0,02 g 0,6155 L02BA03 Fulvestrant(P) 720,5 g 8,3 mg 0,1795 L02BB Anti-androgens 1,4856 L02BB03 Bicalutamide(O) 35558,6 g 0,05 g 1,4705
L02BB04 enzalutamide
(O) 1097,6 g 0,16 g 0,0142
L02BB05 Apalutamide(O) 108 g 0,24 g 0,0009 L02BG Aromatase inhibitors 1,7417 L02BG03 Anastrozole(O) 296,324 g 1 mg 0,6127 L02BG04 Letrozole(O) 1207,95 g 2,5 mg 0,9991 L02BG06 Exemestane(O) 1570,5 g 0,025 g 0,1299 L02BX Other hormone antagonists and related agents 0,0649 L02BX03 Abiraterone(O) 31410 g 1 g 0,0649 L03 IMMUNOSTIMULANTS 0,6755 L03A IMMUNOSTIMULANTS 0,6755 L03AA Colony stimulating factors 0,0747 L03AA02 Filgrastim(P) 8,9256 g 0,35 mg 0,0527 L03AA13 Pegfilgrastim(P) 3,186 g 0,3 mg 0,0220 L03AB Interferons 0,4833 L03AB04 Interferon alfa-2a(P) 35925000000 U 2000000 U 0,0371 L03AB07 Interferon beta-1a(P) 0,6841 g 0,0043 mg 0,3289 L03AB08 Interferon beta-1b(P) 1,2492E+11 U 4000000 U 0,0646 L03AB11 Peginterferon alfa-2a(P) 0,0158 g 0,026 mg 0,0013 L03AB13 Peginterferon beta-1a(P) 0,2211 g 8,9 mcg 0,0514 L03AX Other immunostimulants 0,1175 L03AX03 BCG bacteria(P) 4,3375 g 1,8 mg 0,0050 L03AX13 Glatiramer acetate(P) 1078,24 g 0,02 g 0,1115 L03AX15 Mifamurtide(P) 0,332 g 0,7 mg 0,0010 L03AX16 Plerixafor(P) 0,336 g 16,8 mg <0,0001 L03AX80 Methyluracil(R) 420 g L04 IMMUNOSUPPRESSANTS 6,4862 L04A IMMUNOSUPPRESSANTS 6,4862 L04AA Selective immunosuppressants 1,0819 L04AA03 Antilymphocyte immunoglobulin (horse)(P) 23,75 g L04AA04 Rabbit anti-T-lymphocyte immunoglobulin(P) 15,05 g 0,1 g 0,0003 L04AA06 Mycophenolic acid(O) 274562,4 g 2 g 0,2839 L04AA06 Mycophenolic acid(P) 302 g 2 g 0,0003 L04AA10 Sirolimus(O) 16,65 g 0,003 g 0,0115
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day L04AA13 Leflunomide(O) 5106,6 g 0,02 g 0,5280 L04AA18 Everolimus(O) 0,36 g 1,5 mg 0,0005 L04AA23 Natalizumab(P) 48,9 g 0,01 g 0,0101 L04AA24 Abatacept(P) 162,5 g 0,027 g 0,0124 L04AA25 Eculizumab(P) 37,8 g 0,064 g 0,0012 L04AA27 Fingolimod(O) 5,124 g 0,5 mg 0,0212
L04AA29 Tofacitinib
(O) 52,92 g 10 mg 0,0109
L04AA31 Teriflunomide(O) 670,712 g 14 mg 0,0991 L04AA32 Apremilast(O) 0,69 g 60 mg <0,0001 L04AA33 Vedolizumab(P) 91,5 g 5,4 mg 0,0350 L04AA34 Alemtuzumab(P) 0,78 g 0,13 mg 0,0124 L04AA36 Ocrelizumab(P) 82,5 g 3,29 mg 0,0519 L04AA40 Cladribine(O) 0,52 g 0,34 mg 0,0032 L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors 1,1249 L04AB01 Etanercept(P) 700,4 g 0,007 g 0,2069 L04AB02 Infliximab(P) 978,1 g 3,75 mg 0,5393 L04AB04 Adalimumab(P) 403,64 g 2,9 mg 0,2878 L04AB05 Certolizumab pegol(P) 31,2 g 14 mg 0,0046 L04AB06 Golimumab(P) 69,3 g 1,66 mg 0,0863 L04AC Interleukin inhibitors 0,3520 L04AC02 Basiliximab(P) 0,76 g 0,04 g <0,0001 L04AC03 Anakinra(P) 100,6005 g 0,1 g 0,0021 L04AC05 Ustekinumab(P) 47,275 g 0,54 mg 0,1810 L04AC07 Tocilizumab(P) 725,88 g 0,02 g 0,0750 L04AC10 Secukinumab(P) 379,5 g 10 mg 0,0785 L04AC13 Ixekizumab(P) 3,68 g 2,9 mg 0,0026 L04AC14 Sarilumab(P) 53,3 g 14,3 mg 0,0077 L04AC16 Guselkumab(P) 4,3 g 1,79 mg 0,0050 L04AC18 Risankizumab(P) 0,45 g L04AD Calcineurin inhibitors 0,4759 L04AD01 Ciclosporin(O) 28028,75 g 0,25 g 0,2318 L04AD01 Ciclosporin(P) 55 g 0,25 g 0,0005 L04AD02 Tacrolimus(O) 588,8525 g 5 mg 0,2435 L04AD02 Tacrolimus(P) 0,2 g 5 mg 0,0001 L04AX Other immunosuppressants 3,4515 L04AX01 Azathioprine(O) 27750 g 0,15 g 0,3825 L04AX02 Thalidomide(O) 697,2 g 0,1 g 0,0144 L04AX03 Methotrexate(O) 3360 g 2,5 mg 2,7790 L04AX03 Methotrexate(P) 34,43 g 2,5 mg 0,0285 L04AX04 Lenalidomide(O) 350,91 g 0,01 g 0,0726 L04AX05 Pirfenidone(O) 22540,14 g 2,4 g 0,0194
L04AX06 Pomalidomide
(O) 10,416 g 3 mg 0,0072
L04AX07 Dimethyl fumarate(O) 34345,92 g 0,48 g 0,1480 M MUSCULO-SKELETAL SYSTEM 84,1176 M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS 68,8640
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON- STEROIDS
68,8533
M01AB Acetic acid derivatives and related substances 8,9049 M01AB01 Indometacin(O) 3876,5 g 0,1 g 0,0802 M01AB05 Diclofenac(O) 343897,375 g 0,1 g 7,1108 M01AB05 Diclofenac(P) 9036,75 g 0,1 g 0,1869 M01AB05 Diclofenac(R) 14496,5 g 0,1 g 0,2997 M01AB16 Aceclofenac(O) 40644 g 0,2 g 0,4202 M01AB82 Diclofenac+Omeprazole(O) 39035,25 g 0,1 g 0,8071 M01AC Oxicams 4,0574 M01AC01 Piroxicam(O) 1453,2 g 0,02 g 0,1502 M01AC05 Lornoxicam(O) 1963,84 g 0,012 g 0,3384 M01AC05 Lornoxicam(P) 12,96 g 0,012 g 0,0022
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day M01AC06 Meloxicam(O) 25638,6 g 0,015 g 3,5342 M01AC06 Meloxicam(P) 234,7 g 0,015 g 0,0324 M01AE Propionic acid derivatives 39,3010 M01AE01 Ibuprofen(O) 15104167,6 g 1,2 g 26,0260 M01AE01 Ibuprofen(P) 4052 g 1,2 g 0,0070 M01AE02 Naproxen(O) 546426,1 g 0,5 g 2,2597 M01AE03 Ketoprofen(O) 128869,875 g 0,15 g 1,7764 M01AE03 Ketoprofen(P) 13796 g 0,15 g 0,1902 M01AE17 Dexketoprofen(O) 69992,5 g 0,075 g 1,9297 M01AE17 Dexketoprofen(P) 4123 g 0,075 g 0,1137 M01AE52 Naproxen+Esomeprazole(O) 1689585 g 0,5 g 6,9872 M01AE82 Ibuprofen+Phenylephrine(O) 6542,4 g 1,2 g 0,0113 M01AG Fenamates 0,0035 M01AG02 Tolfenamic acid(O) 508 g 0,3 g 0,0035 M01AH Coxibs 8,3387 M01AH01 Celecoxib(O) 61777 g 0,2 g 0,6387 M01AH05 Etoricoxib(O) 223434,12 g 60 mg 7,7000
M01AX Other antiinflammatory and antirheumatic agents, non-steroids 8,2477
M01AX01 Nabumetone(O) 144040 g 1 g 0,2978 M01AX05 Glucosamine(O) 5767132,71 g 1,5 g 7,9499 M01C SPECIFIC ANTIRHEUMATIC AGENTS 0,0108 M01CC Penicillamine and similar agents 0,0108 M01CC01 Penicillamine(O) 2600 g 0,5 g 0,0108 M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN M02AA Antiinflammatory preparations, non-steroids for topical use M02AA10 Ketoprofen(C) 1189550 g M02AA12 Naproxen(C) 920975 g M02AA13 Ibuprofen(C) 902350 g M02AA15 Diclofenac(C) 385499 pieces M02AA15 Diclofenac(C) 35872477,25 g M02AA81 Ibuprofen+Levomenthol(C) 1766400 g M02AC Preparations with salicylic acid derivatives
M02AC80 Methyl salicylate+Levomenthol+Eucalyptus oil+Turpentine oil(C) 79663 g
M02AX Other topical products for joint and muscular pain M02AX80 Nicoboxil+Nonivamide(C) 183540 g M02AX86 Camphor+Methyl salicylate+Levomenthol(C) 12900 g
M02AX90 Camphor+Salicylic acid+Turpentine oil+Venenum Viperae berus(C) 1063050 g
M02AX92 Benzyl nicotinate+Nonivamide+Camphor+Turpentine oil+Dimethyl sulfoxide(C)
963080 g
M03 MUSCLE RELAXANTS 0,9908 M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS M03AB Choline derivatives M03AB01 Suxamethonium chloride(P) 3615,5 g M03AC Other quaternary ammonium compounds M03AC04 Atracurium besilate(P) 1391,5 g M03AC06 Pipecuronium bromide(P) 31,2 g M03AC09 Rocuronium bromide(P) 976 g M03AX Other muscle relaxants, peripherally acting agents M03AX01 Botulinum toxin(P) 1345200 U M03B MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS 0,9908 M03BX Other centrally acting agents 0,9908 M03BX01 Baclofen(O) 4624,25 g 0,05 g 0,1912 M03BX01 Baclofen(P) 2,8218 g 0,55 mg 0,0106 M03BX02 Tizanidine(O) 4573,68 g 0,012 g 0,7881 M03BX04 Tolperisone(O) 81 g 0,2 g 0,0008 M03C MUSCLE RELAXANTS, DIRECTLY ACTING AGENTS
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day M03CA Dantrolene and derivatives M03CA01 Dantrolene(P) 15,12 g M04 ANTIGOUT PREPARATIONS 9,4479 M04A ANTIGOUT PREPARATIONS 9,4479 M04AA Preparations inhibiting uric acid production 9,4323 M04AA01 Allopurinol(O) 1286950 g 0,4 g 6,6526 M04AA03 Febuxostat(O) 107546,88 g 0,08 g 2,7797 M04AB Preparations increasing uric acid excretion 0,0055 M04AB03 Benzbromarone(O) 268 g 0,1 g 0,0055 M04AC Preparations with no effect on uric acid metabolism 0,0100 M04AC01 Colchicine(O) 4,855 g 1 mg 0,0100 M05 DRUGS FOR TREATMENT OF BONE DISEASES 4,8148
M05B DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION 4,8148
M05BA Bisphosphonates 0,9000 M05BA03 Pamidronic acid(P) 22,62 g 0,06 g 0,0008 M05BA04 Alendronic acid(O) 742 g 0,01 g 0,1534 M05BA06 Ibandronic acid(O) 1344,15 g 0,005 g 0,5559 M05BA06 Ibandronic acid(P) 1,83 g 0,006 g 0,0006 M05BA07 Risedronic acid(O) 436,1 g 0,005 g 0,1803 M05BA08 Zoledronic acid(P) 17,232 g 0,004 g 0,0089 M05BB Bisphosphonates, combinations 2,7503 M05BB03 Alendronic acid+Colecalciferol(O) 13301,12 g 10 mg 2,7503 M05BX Other drugs affecting bone structure and mineralization 1,1646 M05BX04 Denosumab(P) 185,864 g 0,33 mg 1,1646 M05BX05 Burosumab(P) 0,53 g N NERVOUS SYSTEM 134,1934 N01 ANESTHETICS N01A ANESTHETICS, GENERAL N01AB Halogenated hydrocarbons N01AB06 Isoflurane(I) 14400 ml N01AB07 Desflurane(I) 73440 ml N01AB08 Sevoflurane(I) 778750 ml N01AF Barbiturates, plain N01AF03 Thiopental(P) 2130 g N01AH Opioid anesthetics N01AH01 Fentanyl(I) 30,872 g N01AH01 Fentanyl(P) 2,003 g N01AH06 Remifentanil(P) 15,115 g N01AX Other general anesthetics N01AX03 Ketamine(P) 419 g N01AX07 Etomidate(P) 74,2 g N01AX10 Propofol(P) 64708,5 g N01AX11 Sodium oxybate(P) 1660 g N01AX13 Nitrous oxide(I) 11116000 ml N01AX14 Esketamine(P) 374,5 g N01B ANESTHETICS, LOCAL N01BA Esters of aminobenzoic acid N01BA02 Procaine(P) 1,25 g N01BB Amides N01BB01 Bupivacaine(Infilt, P) 3084,45 g N01BB01 Bupivacaine(P) 285,4 g N01BB02 Lidocaine(C) 1300 ml N01BB02 Lidocaine(C) 2215,5 g N01BB02 Lidocaine(NA) 85200 ml N01BB02 Lidocaine(O) 65100 g N01BB02 Lidocaine(P) 25379,1 g N01BB03 Mepivacaine(dental) 1565,7 g N01BB08 Articaine(P) 2,4 g N01BB09 Ropivacaine(P) 733,9 g
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day N01BB80 Articaine+Epinephrine(dental) 1236070 ml N01BB80 Articaine+Epinephrine(O) 230310 ml N01BB81 Bupivacaine+Epinephrine(P) 250400 ml N01BB82 Lidocaine+Epinephrine(dental) 180 ml N01BB82 Lidocaine+Epinephrine(P) 62400 ml N01BB83 Lidocaine+Prilocaine(C) 53650 g N01BB86 Lidocaine+Chlorhexidine(urethral) 1096175 g N01BB87 Mepivacaine+Epinephrine(P) 90 ml N01BC Esters of benzoic acid N01BC01 Cocaine(NA) 285 g N01BX Other local anesthetics N01BX04 Capsaicin(C) 77,486 g N02 ANALGESICS 23,5231 N02A OPIOIDS 7,7385 N02AA Natural opium alkaloids 0,7684 N02AA01 Morphine(O) 6033 g 0,1 g 0,1247 N02AA01 Morphine(P) 700,8 g 0,03 g 0,0483 N02AA05 Oxycodone(O) 17711,05 g 0,075 g 0,4883 N02AA05 Oxycodone(P) 27,65 g 0,03 g 0,0019 N02AA08 Dihydrocodeine(O) 7401 g 0,15 g 0,1020 N02AA55 Oxycodone+Naloxone(O) 115,2 g 75 mg 0,0032 N02AB Phenylpiperidine derivatives 0,1536 N02AB02 Pethidine(P) 22 g 0,4 g 0,0001 N02AB02 Pethidine(P, V) 3034 g 0,4 g 0,0157 N02AB03 Fentanyl(O) 2,9792 g N02AB03 Fentanyl(SL) 2,986 g 0,6 mg 0,0103 N02AB03 Fentanyl(TD) 74,0196 g 1,2 mg 0,1275 N02AE Oripavine derivatives 0,0101 N02AE01 Buprenorphine(TD) 5,8666 g 1,2 mg 0,0101 N02AJ Opioids in combination with non-opioid analgesics 4,9355 N02AJ06 Codeine+Paracetamol(O) 5858890 pieces 3 pieces 4,0382 N02AJ13 Tramadol+Paracetamol(O) 1880,25 g 150 mg 0,0259 N02AJ14 Tramadol+Dexketoprofen(O) 63216 g 150 mg 0,8714 N02AX Other opioids 1,8708 N02AX02 Tramadol(O) 266855 g 0,3 g 1,8393 N02AX02 Tramadol(P) 4571 g 0,3 g 0,0315 N02AX02 Tramadol(R) 1 g 0,3 g <0,0001 N02B OTHER ANALGESICS AND ANTIPYRETICS 14,8474 N02BA Salicylic acid and derivatives 0,9048 N02BA01 Acetylsalicylic acid (O) 1109871,96 g 3 g 0,7650 N02BA80 Acetylsalicylic acid +Ascorbic acid(O) 202830 g 3 g 0,1398 N02BB Pyrazolones 0,0021 N02BB02 Metamizole sodium(O) 235 g 3 g 0,0002 N02BB02 Metamizole sodium(P, V) 2810 g 3 g 0,0019 N02BE Anilides 13,9405 N02BE01 Paracetamol(O) 13820637,2 g 3 g 9,5257 N02BE01 Paracetamol(P) 291250 g 3 g 0,2007 N02BE01 Paracetamol(R) 67488,55 g 3 g 0,0465 N02BE52 Paracetamol+Pseudoephedrine+Diphenhydramine(O) 58784 g 3 g 0,0405 N02BE75 Paracetamol+Guaifenesin+Phenylephrine(O) 255404,5 g 3 g 0,1760
N02BE81 Paracetamol+Chlorphenamine+Pseudoephedrine+Dextromethorphan( O)
429356 g 3 g 0,2959
N02BE83 Paracetamol+Caffeine(O) 194850 g 3 g 0,1343 N02BE84 Paracetamol+Phenylephrine+Ascorbic acid(O) 1296233,75 g 3 g 0,8934 N02BE85 Paracetamol+Pheniramine+Ascorbic acid(O) 106990,4 g 3 g 0,0737
N02BE86 Paracetamol+Phenylephrine+Terpin hydrate+Ascorbic acid+Caffeine(O)
408894 g 3 g 0,2818
N02BE87 Paracetamol+Pseudoephedrine(O) 66250 g 3 g 0,0457 N02BE91 Paracetamol+Ascorbic acid(O) 3696 g 3 g 0,0025 N02BE92 Paracetamol+Codeine(O) 918760 g 3 g 0,6332
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day N02BE94 Paracetamol+Codeine+Caffeine(O) 1760004 g 3 g 1,2131 N02BE95 Paracetamol+Phenylephrine(O) 73835 g 3 g 0,0509 N02BE97 Paracetamol+Pseudoephedrine+Dextromethorphan(O) 473518 g 3 g 0,3264 N02C ANTIMIGRAINE PREPARATIONS 0,9372 N02CC Selective serotonin (5HT1) agonists 0,9278 N02CC01 Sumatriptan(N) 1,96 g 0,02 g 0,0002 N02CC01 Sumatriptan(O) 19058,4 g 0,05 g 0,7881 N02CC03 Zolmitriptan(O) 49,09 g 2,5 mg 0,0406 N02CC04 Rizatriptan(O) 69,75 g 0,01 g 0,0144 N02CC07 Frovatriptan(O) 102,125 g 2,5 mg 0,0845 N02CD Calcitonin gene-related peptide (CGRP) antagonists 0,0094 N02CD01 Erenumab(P) 11,34 g 2,5 mg 0,0094 N03 ANTIEPILEPTICS 10,9169 N03A ANTIEPILEPTICS 10,9169 N03AA Barbiturates and derivatives 0,4606 N03AA02 Phenobarbital(O) 19655 g 0,1 g 0,4064 N03AA02 Phenobarbital(P) 70 g 0,1 g 0,0014 N03AA03 Primidone(O) 31900 g 1,25 g 0,0528 N03AB Hydantoin derivatives 0,0414 N03AB02 Phenytoin(O) 5810 g 0,3 g 0,0400 N03AB02 Phenytoin(P) 197,5 g 0,3 g 0,0014 N03AD Succinimide derivatives 0,0138 N03AD01 Ethosuximide(O) 8350 g 1,25 g 0,0138 N03AE Benzodiazepine derivatives 0,5706 N03AE01 Clonazepam(O) 2207,76 g 0,008 g 0,5706 N03AE01 Clonazepam(P) 0,005 g 0,008 g <0,0001 N03AF Carboxamide derivatives 2,8644 N03AF01 Carbamazepine(O) 991171 g 1 g 2,0495 N03AF02 Oxcarbazepine(O) 393825 g 1 g 0,8143 N03AF03 Rufinamide(O) 400 g 1,4 g 0,0006 N03AG Fatty acid derivatives 1,6063 N03AG01 Valproic acid(O) 1153930 g 1,5 g 1,5907 N03AG01 Valproic acid(P) 1043,1 g 1,5 g 0,0014 N03AG04 Vigabatrin(O) 13750 g 2 g 0,0142 N03AX Other antiepileptics 5,3597 N03AX03 Sultiame(O) 3990 g 0,4 g 0,0206 N03AX09 Lamotrigine(O) 98749,28 g 0,3 g 0,6806 N03AX11 Topiramate(O) 34845 g 0,3 g 0,2402 N03AX12 Gabapentin(O) 1308465 g 1,8 g 1,5031 N03AX14 Levetiracetam(O) 440850 g 1,5 g 0,6077 N03AX14 Levetiracetam(P) 260 g 1,5 g 0,0004 N03AX16 Pregabalin(O) 334306,35 g 0,3 g 2,3042 N03AX17 Stiripentol(O) 1245 g 1 g 0,0026 N03AX18 Lacosamide(O) 7,7 g 0,3 g 0,0001 N03AX22 perampanel(O) 1,344 g 8 mg 0,0003 N04 ANTI-PARKINSON DRUGS 3,7744 N04A ANTICHOLINERGIC AGENTS 0,6093 N04AA Tertiary amines 0,6093 N04AA01 Trihexyphenidyl(O) 2946,6 g 0,01 g 0,6093 N04B DOPAMINERGIC AGENTS 3,1652 N04BA Dopa and dopa derivatives 1,4237 N04BA03 Levodopa +Carbidopa+Entacapone(O) 71752,5 g 0,45 g 0,3297 N04BA80 Levodopa +Benserazide(O) 310370 g 0,6 g 1,0696 N04BA81 Levodopa +Carbidopa(intestin) 18676 g N04BA81 Levodopa +Carbidopa(O) 7085,9 g 0,6 g 0,0244 N04BB Adamantane derivatives 0,3031 N04BB01 Amantadine(O) 29320 g 0,2 g 0,3031 N04BB01 Amantadine(P) 36 g N04BC Dopamine agonists 0,7715 N04BC04 Ropinirole(O) 1045,667 g 0,006 g 0,3604
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day N04BC05 Pramipexole(O) 466,1869 g 2,5 mg 0,3856 N04BC07 Apomorphine(P) 246,9 g 20 mg 0,0255 N04BD Monoamine oxidase type B inhibitors 0,6669 N04BD02 Rasagiline(O) 322,51 g 0,001 g 0,6669 N05 PSYCHOLEPTICS 43,6288 N05A ANTIPSYCHOTICS 9,5838 N05AA Phenothiazines with aliphatic side-chain 0,1621 N05AA01 Chlorpromazine(O) 12357 g 0,3 g 0,0852 N05AA01 Chlorpromazine(P) 54 g 0,1 g 0,0011 N05AA02 Levomepromazine(O) 10969 g 0,3 g 0,0756 N05AA02 Levomepromazine(P, V) 12,5 g 0,1 g 0,0003 N05AB Phenothiazines with piperazine structure 0,0698 N05AB02 Fluphenazine(P) 3,5 g 0,001 g 0,0072 N05AB03 Perphenazine(O) 423,2 g 0,03 g 0,0292 N05AB03 Perphenazine(P) 161,218 g 0,01 g 0,0333 N05AB04 Prochlorperazine(O) 2,94 g 0,1 g 0,0001 N05AC Phenothiazines with piperidine structure 0,0012 N05AC01 Periciazine(O) 28,8 g 0,05 g 0,0012 N05AC02 Thioridazine(O) 2,5 g 0,3 g <0,0001 N05AD Butyrophenone derivatives 1,0330 N05AD01 Haloperidol(O) 2091,99 g 0,008 g 0,5407 N05AD01 Haloperidol(P) 805,525 g 0,008 g 0,2082 N05AD03 Melperone(O) 38880 g 0,3 g 0,2680 N05AD08 Droperidol(P) 19,45 g 2,5 mg 0,0161 N05AE Indole derivatives 0,0995 N05AE03 Sertindole(O) 739,424 g 0,016 g 0,0956 N05AE04 Ziprasidone(O) 149,28 g 0,08 g 0,0039 N05AE05 Lurasidone(O) 2,604 g 60 mg 0,0001 N05AF Thioxanthene derivatives 0,8720 N05AF01 Flupentixol(O) 364,4 g 0,006 g 0,1256 N05AF01 Flupentixol(P) 109 g 0,004 g 0,0563 N05AF03 Chlorprothixene(O) 29695 g 0,3 g 0,2047 N05AF05 Zuclopenthixol(O) 1368 g 0,03 g 0,0943 N05AF05 Zuclopenthixol(P) 47,5 g 0,03 g 0,0033 N05AF05 Zuclopenthixol(P) 2813,6 g 0,015 g 0,3878 N05AG Diphenylbutylpiperidine derivatives 0,0001 N05AG02 Pimozide(O) 0,225 g 0,004 g 0,0001 N05AH Diazepines, oxazepines and thiazepines 5,4396 N05AH02 Clozapine(O) 91236,75 g 0,3 g 0,6288 N05AH03 Olanzapine(O) 10312,68 g 0,01 g 2,1324 N05AH03 Olanzapine(P) 154,4 g 0,01 g 0,0319 N05AH04 Quetiapine(O) 511891 g 0,4 g 2,6461 N05AH05 Asenapine(SL) 3 g 20 mg 0,0003 N05AL Benzamides 0,1453 N05AL01 Sulpiride(O) 21868,5 g 0,8 g 0,0565 N05AL05 Amisulpride(O) 17172 g 0,4 g 0,0888 N05AN Lithium 0,2623 N05AN01 Lithium(O) 114180 g 0,9 g 0,2623 N05AX Other antipsychotics 1,4989 N05AX08 Risperidone(O) 1623,2 g 0,005 g 0,6713 N05AX08 Risperidone(P) 22,275 g 2,7 mg 0,0171 N05AX12 Aripiprazole(O) 4895,16 g 0,015 g 0,6748 N05AX12 Aripiprazole(P) 8,8725 g 0,015 g 0,0012 N05AX12 Aripiprazole(P) 394,4 g 0,0133 g 0,0613 N05AX13 Paliperidone(P) 87,9 g 2,5 mg 0,0727 N05AX15 Cariprazine(O) 0,756 g 3 mg 0,0005 N05B ANXIOLYTICS 13,0269 N05BA Benzodiazepine derivatives 13,0262 N05BA01 Diazepam(O) 26947,05 g 0,01 g 5,5719 N05BA01 Diazepam(P) 490,7 g 0,01 g 0,1015
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day N05BA01 Diazepam(R) 60,15 g 0,01 g 0,0124 N05BA02 Chlordiazepoxide(O) 0,5 g 0,03 g <0,0001 N05BA04 Oxazepam(O) 6,5 g 0,05 g 0,0003 N05BA06 Lorazepam(O) 735,555 g 2,5 mg 0,6084 N05BA06 Lorazepam(P) 10,76 g 2,5 mg 0,0089 N05BA08 Bromazepam(O) 5716,95 g 0,01 g 1,1821 N05BA09 Clobazam(O) 333 g 0,02 g 0,0344 N05BA12 Alprazolam(O) 2655,47 g 0,001 g 5,4908 N05BA80 Phenazepam(O) 7,525 g 0,001 g 0,0156 N05BB Diphenylmethane derivatives 0,0002 N05BB01 Hydroxyzine(O) 6,3 g 0,075 g 0,0002 N05BE Azaspirodecanedione derivatives 0,0005 N05BE01 Buspirone(O) 7,2 g 0,03 g 0,0005 N05C HYPNOTICS AND SEDATIVES 21,0181 N05CD Benzodiazepine derivatives 0,3026 N05CD02 Nitrazepam(O) 272,85 g 0,005 g 0,1128 N05CD05 Triazolam(O) 0,03 g 0,25 mg 0,0002 N05CD08 Midazolam(O) 0,24 g N05CD08 Midazolam(O) 974,8997 g 0,015 g 0,1344 N05CD08 Midazolam(P) 400,2199 g 0,015 g 0,0552 N05CF Benzodiazepine related drugs 20,3792 N05CF01 Zopiclone(O) 58842,525 g 7,5 mg 16,2226 N05CF02 Zolpidem(O) 20102 g 0,01 g 4,1565 N05CM Other hypnotics and sedatives 0,3363 N05CM09 Valerianae radix(O) 468750 pieces 3 pieces 0,3231 N05CM18 Dexmedetomidine(P) 6,3842 g 1 mg 0,0132 N06 PSYCHOANALEPTICS 39,8858 N06A ANTIDEPRESSANTS 34,7835 N06AA Non-selective monoamine reuptake inhibitors 1,9432 N06AA04 Clomipramine(O) 4674,15 g 0,1 g 0,0966 N06AA04 Clomipramine(P) 2,5 g 0,1 g 0,0001 N06AA09 Amitriptyline(O) 53941,75 g 0,075 g 1,4872 N06AA10 Nortriptyline(O) 13032,5 g 0,075 g 0,3593 N06AB Selective serotonin reuptake inhibitors 20,5822 N06AB03 Fluoxetine(O) 32820,04 g 0,02 g 3,3931 N06AB04 Citalopram(O) 13807,26 g 0,02 g 1,4275 N06AB05 Paroxetine(O) 22974,6 g 0,02 g 2,3752 N06AB06 Sertraline(O) 130599,3 g 0,05 g 5,4008 N06AB08 Fluvoxamine(O) 305,5 g 0,1 g 0,0063 N06AB10 Escitalopram(O) 38589,16 g 0,01 g 7,9791 N06AF Monoamine oxidase inhibitors, non-selective 0,0050 N06AF04 Tranylcypromine(O) 24 g 0,01 g 0,0050 N06AG Monoamine oxidase type A inhibitors 0,0001 N06AG02 Moclobemide(O) 15 g 0,3 g 0,0001 N06AX Other antidepressants 12,2531 N06AX03 Mianserin(O) 24,3 g 0,06 g 0,0008 N06AX05 Trazodone(O) 6357 g 0,3 g 0,0438 N06AX11 Mirtazapine(O) 33217,02 g 0,03 g 2,2894 N06AX12 Bupropione(O) 107356,5 g 0,3 g 0,7399 N06AX14 Tianeptine(O) 25214,625 g 0,0375 g 1,3903 N06AX16 Venlafaxine(O) 167874,6 g 0,1 g 3,4712 N06AX18 Reboxetine(O) 1,44 g 0,008 g 0,0004 N06AX21 Duloxetine(O) 67255,62 g 0,06 g 2,3178 N06AX22 Agomelatine(O) 17253,6 g 0,025 g 1,4270 N06AX26 Vortioxetine(O) 2768,36 g 10 mg 0,5724
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
1,3297
N06BA Centrally acting sympathomimetics 1,0734 N06BA04 Methylphenidate(O) 14412,18 g 0,03 g 0,9933 N06BA07 Modafinil(O) 1064 g 0,3 g 0,0073
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day N06BA09 Atomoxetine(O) 2814,504 g 0,08 g 0,0727 N06BA12 Lisdexamfetamine dimesylate(O) 8,1 g N06BC Xanthine derivatives N06BC81 Caffeine citrate(O, P) 51,2 g N06BX Other psychostimulants and nootropics 0,2563 N06BX03 Piracetam (O) 281304 g 2,4 g 0,2424 N06BX13 Idebenone(O) 918 g 0,9 g 0,0021 N06BX18 Vinpocetine(O) 85,5 g 15 mg 0,0118 N06BX83 Aminobutyric acid(O) 25320 g N06D ANTI-DEMENTIA DRUGS 3,7727 N06DA Anticholinesterases 0,9913 N06DA02 Donepezil(O) 3595,48 g 7,5 mg 0,9913 N06DX Other anti-dementia drugs 2,7814 N06DX01 Memantine(O) 4312,64 g 0,02 g 0,4459 N06DX02 Ginkgo folium(O) 135543,6 g 0,12 g 2,3355 N06DX80 cerebrolysine(P) 4,304 g N07 OTHER NERVOUS SYSTEM DRUGS 12,4644 N07A PARASYMPATHOMIMETICS 0,3831 N07AA Anticholinesterases 0,3831 N07AA01 neostigmine(P) 31,43 g 0,002 g 0,0325 N07AA02 Pyridostigmine bromide(O) 28146 g 0,18 g 0,3233 N07AA03 Distigmine bromide(O) 0,5 g 0,005 g 0,0002 N07AA80 Neostigmine+Glycopyrronium(P) 13110 ml 1 ml 0,0271 N07B DRUGS USED IN ADDICTIVE DISORDERS 3,5444 N07BA Drugs used in nicotine dependence 1,9211 N07BA01 Nicotine(O) 17724,55 g 0,03 g 1,2216 N07BA01 Nicotine(TD) 4436,775 g 0,014 g 0,6553 N07BA03 Varenicline(O) 42,751 g 2 mg 0,0442 N07BB Drugs used in alcohol dependence 0,4070 N07BB01 Disulfiram(O) 33255 g 0,2 g 0,3438 N07BB01 Disulfiram(P) 51 g N07BB03 Acamprosate(O) 55,944 g 2 g 0,0001 N07BB04 Naltrexone(O) 1207,4 g 50 mg 0,0499 N07BB05 nalmefene(O) 115,164 g 18 mg 0,0132 N07BC Drugs used in opioid dependence 1,2163 N07BC02 Methadone(O) 14155 g 0,025 g 1,1707 N07BC51 Buprenorphine+Naloxone(SL) 176,148 g 8 mg 0,0455 N07C ANTIVERTIGO PREPARATIONS 8,5003 N07CA Antivertigo preparations 8,5003 N07CA01 Betahistine(O) 84375,6 g 0,024 g 7,2694 N07CA02 Cinnarizine(O) 51543,75 g 0,09 g 1,1842 N07CA03 Flunarizine(O) 3,15 g 0,01 g 0,0007 N07CA80 Cinnarizine+Dimenhydrinate(O) 2005 g 90 mg 0,0461 N07X OTHER NERVOUS SYSTEM DRUGS 0,0366 N07XX Other nervous system drugs 0,0366 N07XX02 Riluzole(O) 1481,2 g 0,1 g 0,0306 N07XX06 Tetrabenazine(O) 249,2 g 0,1 g 0,0052 N07XX07 Fampridine(O) 7,84 g 20 mg 0,0008 N07XX14 Edaravone(P) 2,7 g
P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS 0,9680
P01 ANTIPROTOZOALS 0,7483
P01A AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES
P01AB Nitroimidazole derivatives P01AB01 Metronidazole (O, V) 1962 g P01B ANTIMALARIALS 0,7483 P01BA Aminoquinolines 0,7036 P01BA02 Hydroxychloroquine(O) 175440 g 0,516 g 0,7030 P01BA03 Primaquine(O) 4,5 g 0,015 g 0,0006
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day P01BB Biguanides 0,0440 P01BB51 Proguanil+Atovaquone(O) 1740 pieces 16 pieces 0,0002 P01BB51 Proguanil+Atovaquone(O) 84612 pieces 4 pieces 0,0437 P01BC Methanolquinolines <0,0001 P01BC02 Mefloquine(O) 6 g 1 g <0,0001 P01BD Diaminopyrimidines 0,0006 P01BD01 Pyrimethamine(O) 23,25 g 0,075 g 0,0006 P01C AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS <0,0001 P01CX Other agents against leishmaniasis and trypanosomiasis <0,0001 P01CX01 Pentamidine isethionate(P) 1,5 g 0,28 g <0,0001 P02 ANTHELMINTICS 0,2197 P02B ANTITREMATODALS 0,0003 P02BA Quinoline derivatives and related substances 0,0003 P02BA01 Praziquantel(O) 385,2 g 3 g 0,0003 P02C ANTINEMATODAL AGENTS 0,2194 P02CA Benzimidazole derivatives 0,2191 P02CA01 Mebendazole(O) 19592 g 0,2 g 0,2026 P02CA03 Albendazole(O) 3200 g 0,4 g 0,0165 P02CF Avermectines 0,0003 P02CF01 Ivermectin(O) 1,956 g 12 mg 0,0003
P03 ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
P03A ECTOPARASITICIDES, INCL. SCABICIDES P03AC Pyrethrines, incl. synthetic compounds P03AC04 Permethrin(C) 58600 g P03AX Other ectoparasiticides, incl. scabicides P03AX01 Benzyl benzoate(C) 344730 g R RESPIRATORY SYSTEM 93,8787 R01 NASAL PREPARATIONS 38,4271
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
35,6572
R01AA Sympathomimetics, plain 22,8751 R01AA05 Oxymetazoline(N) 315,3 g 0,4 mg 1,6299 R01AA07 Xylometazoline(N) 8219,765 g 0,8 mg 21,2452 R01AB Sympathomimetics, combinations excl. corticosteroids 3,0493 R01AB83 Xylometazoline+Ipratropium bromide(N) 238100 ml 0,8 ml 0,6154 R01AB85 Xylometazoline+Dexpanthenol(N) 941680 ml 0,8 ml 2,4339 R01AC Antiallergic agents, excl. corticosteroids 0,3321 R01AC03 Azelastine(N) 89,93 g 0,56 mg 0,3321 R01AD Corticosteroids 9,4007 R01AD01 Beclometasone(N) 7,57 g 0,4 mg 0,0391 R01AD05 Budesonide(N) 41,513 g 0,2 mg 0,4292 R01AD08 Fluticasone(N) 92,313 g 0,2 mg 0,9544 R01AD09 Mometasone(N) 402,346 g 0,2 mg 4,1597 R01AD12 Fluticasone furoate(N) 179,8368 g 0,11 mg 3,3805 R01AD81 Fluticasone+Azelastine(N) 847080 doses 4 doses 0,4379 R01AX Other nasal preparations R01AX06 Mupirocin(N) 21 g R01AX83 Retinol+Tocopherol(N) 156860 ml R01B NASAL DECONGESTANTS FOR SYSTEMIC USE 2,7699 R01BA Sympathomimetics 2,7699 R01BA02 Pseudoephedrine(O) 179500,68 g 0,24 g 1,5465 R01BA81 Pseudoephedrine+Triprolidine(O) 33867,12 g 0,24 g 0,2918 R01BA84 Pseudoephedrine+Guaifenesin(O) 10288,8 g 0,24 g 0,0886 R01BA89 Pseudoephedrine+Loratadine(O) 18224,64 g 0,24 g 0,1570 R01BA93 Pseudoephedrine+Cetirizine(O) 79625,28 g 0,24 g 0,6860 R02 THROAT PREPARATIONS 2,8356 R02A THROAT PREPARATIONS 2,8356 R02AA Antiseptics 2,3211 R02AA06 Cetylpyridinium chloride(O) 122526 pieces
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day R02AA82 Benzydamine+Cetylpyridinium chloride(O) 1197750 ml R02AA82 Benzydamine+Cetylpyridinium chloride(O) 1908656 pieces 6 pieces 0,6578 R02AA89 Povidone, iodinated+Allantoin(O) 357870 ml R02AA92 Dequalinium+Cinchocaine(O) 1039020 pieces 6 pieces 0,3581 R02AA94 Amylmetacresol+Dichlorobenzyl alcohol(O) 1028304 pieces 6 pieces 0,3544 R02AA95 Amylmetacresol+Dichlorobenzyl alcohol+Levomenthol(O) 1749528 pieces 6 pieces 0,6029 R02AA96 Amylmetacresol+Dichlorobenzyl alcohol+Ascorbic acid(O) 634872 pieces 6 pieces 0,2188 R02AA98 Cetylpyridinium chloride+Benzocaine(O) 374886 pieces 6 pieces 0,1292 R02AD Anesthetics, local 0,1534 R02AD80 Lidocaine+Propyl parahydroxybenzoate(O) 445060 pieces 6 pieces 0,1534 R02AX Other throat preparations 0,3611 R02AX01 Flurbiprofen(O) 7683,97 g 44 mg 0,3611 R02AX80 Thyme herb+Sage leaf(O) 32475 ml R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES 27,2911 R03A ADRENERGICS, INHALANTS 19,3775 R03AC Selective beta-2-adrenoceptor agonists 4,1496 R03AC02 Salbutamol(I) 989,816 g 0,8 mg 2,5583 R03AC02 Salbutamol(I) 1754,6 g 0,01 g 0,3628 R03AC04 Fenoterol(I) 63,84 g 0,6 mg 0,2200 R03AC12 Salmeterol(I) 4,98 g 0,1 mg 0,1030 R03AC13 Formoterol(I) 6,6281 g 0,024 mg 0,5710 R03AC18 Indacaterol(I) 24,264 g 0,15 mg 0,3345
R03AK Adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics
11,8364
R03AK06 Salmeterol+Fluticasone(I) 572040 doses 4 doses 0,2957 R03AK06 Salmeterol+Fluticasone(I) 2364240 doses 2 doses 2,4443 R03AK07 Formoterol+Budesonide(I) 1114560 doses 2 doses 1,1523 R03AK07 Formoterol+Budesonide(I) 5776080 doses 4 doses 2,9858 R03AK08 Formoterol+Beclometasone(I) 2948220 doses 4 doses 1,5240 R03AK10 Vilanterol+Fluticasone furoate(I) 1635690 doses 1 doses 3,3821 R03AK13 Salbutamol+Beclometasone(I) 100800 doses 4 doses 0,0521
R03AL Adrenergics in combinations with anticholinergics incl. triple combinations with corticosteroids
3,3915
R03AL01 Fenoterol+Ipratropium bromide(I) 185820 ml 16 ml 0,0240 R03AL01 Fenoterol+Ipratropium bromide(I) 2399000 doses 6 doses 0,8267 R03AL03 Vilanterol+Umeclidinium(I) 326820 doses 1 doses 0,6758 R03AL04 Indacaterol+Glycopyrronium(I) 218220 doses 1 doses 0,4512 R03AL05 Formoterol+Aclidinium(I) 351840 doses 2 doses 0,3638 R03AL06 Olodaterol+Tiotropium(I) 669060 doses 2 doses 0,6917 R03AL07 Formoterol+Glycopyrronium(I) 37920 doses 4 doses 0,0196 R03AL08 Vilanterol+Umeclidinium+Fluticasone furoate(I) 39270 doses 1 doses 0,0812 R03AL09 Formoterol+Glycopyrronium+Beclometasone(I) 498120 doses 4 doses 0,2575
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
4,8834
R03BA Glucocorticoids 1,6251 R03BA01 Beclometasone(I) 0,3 g 1,5 mg 0,0004 R03BA02 Budesonide(I) 160,48 g 1,5 mg 0,2212 R03BA02 Budesonide(I) 312,276 g 0,8 mg 0,8071 R03BA05 Fluticasone(I) 173,037 g 0,6 mg 0,5963 R03BB Anticholinergics 3,2583 R03BB01 Ipratropium bromide(I) 22,028 g 0,12 mg 0,3796 R03BB01 Ipratropium bromide(I) 27,645 g 0,3 mg 0,1905 R03BB04 Tiotropium(I) 3,4869 g 0,005 mg 1,4420 R03BB05 Aclidinium(I) 131,7238 g 0,644 mg 0,4229 R03BB06 Glycopyrronium(I) 8,9866 g 44 mcg 0,4223 R03BB07 Umeclidinium(I) 10,6656 g 55 mcg 0,4010 R03C ADRENERGICS FOR SYSTEMIC USE 0,1451 R03CC Selective beta-2-adrenoceptor agonists 0,1451 R03CC02 Salbutamol(O) 841,8 g 0,012 g 0,1451 R03CC02 Salbutamol(P) 0,1475 g 0,012 g <0,0001
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day R03CC03 Terbutaline(O) 0,5 g 0,015 g 0,0001
R03D OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
2,8850
R03DA Xanthines 1,2529 R03DA04 Theophylline(O) 238710 g 0,4 g 1,2340 R03DA05 Aminophylline(P) 5500,8 g 0,6 g 0,0190 R03DC Leukotriene receptor antagonists 1,5850 R03DC03 Montelukast(O) 7665,672 g 0,01 g 1,5850 R03DX Other systemic drugs for obstructive airway diseases 0,0471 R03DX05 Omalizumab(P) 198 g 0,016 g 0,0256 R03DX09 Mepolizumab(P) 19,8 g 3,6 mg 0,0114 R03DX10 Benralizumab(P) 2,64 g 0,54 mg 0,0101 R05 COUGH AND COLD PREPARATIONS 7,7293
R05C EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS
7,5640
R05CA Expectorants 0,0954 R05CA03 Guaifenesin(O) 41503,2 g 0,9 g 0,0954 R05CA12 Hederae helicis folium(O) 155796 pieces R05CA12 Hederae helicis folium(O) 7816865 ml R05CA86 Iceland moss(O) 9437400 ml
R05CA87 Distillate of rectified essential oils of eucalyptus, sweet orange, myrtle and lemon(O)
1369500 pieces
R05CA88 Thyme herb+Wild thyme+Plantain(O) 489600 ml R05CA89 Thyme herb+Hederae helicis folium(O) 376700 ml R05CA91 Thyme herb+Marshmallow root(O) 5122950 ml R05CA92 Thyme herb(O) 270620 pieces R05CB Mucolytics 7,4687 R05CB01 Acetylcysteine(I, P) 75 g R05CB01 Acetylcysteine(O) 1029638,8 g 0,5 g 4,2580 R05CB01 Acetylcysteine(P) 7065 g R05CB02 Bromhexine(O) 8138 g 0,024 g 0,7011 R05CB03 Carbocisteine(O) 187155 g 1,5 g 0,2580 R05CB06 Ambroxol(O) 129473,7 g 0,12 g 2,2310 R05CB13 Dornase alfa(I) 24,885 g 2,5 mg 0,0206
R05D COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
0,1072
R05DB Other cough suppressants 0,1072 R05DB09 Oxeladin(O) 4148 g 0,08 g 0,1072
R05F COUGH SUPPRESSANTS AND EXPECTORANTS, COMBINATIONS 0,0581
R05FA Opium derivatives and expectorants 0,0581 R05FA80 Codeine+Guaifenesin(O) 842700 ml 30 ml 0,0581 R05X OTHER COLDPREPARATIONS R05XA Other cold combination preparations
R05XA80 Gentian root+Primula flower+Common sorrel+Elder flower+Verbena herb(O)
3764,8 g
R05XA80 Gentian root+Primula flower+Common sorrel+Elder flower+Verbena herb(O)
1815140 pieces
R05XA82 Ibuprofen+Pseudoephedrine(O) 10704 g R06 ANTIHISTAMINES FOR SYSTEMIC USE 17,5952 R06A ANTIHISTAMINES FOR SYSTEMIC USE 17,5952 R06AA Aminoalkyl ethers 0,4752 R06AA02 Diphenhydramine(O) 38 g 0,2 g 0,0004 R06AA02 Diphenhydramine(P) 19 g R06AA04 Clemastine(O) 418,64 g 0,002 g 0,4328 R06AA04 Clemastine(P) 40,64 g 0,002 g 0,0420 R06AE Piperazine derivatives 8,8925 R06AE07 Cetirizine(O) 40649,015 g 0,01 g 8,4051 R06AE09 Levocetirizine(O) 1178,64 g 0,005 g 0,4874 R06AX Other antihistamines for systemic use 8,2275
37/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day R06AX13 Loratadine(O) 18664,5 g 0,01 g 3,8593 R06AX15 Mebhydrolin(O) 20 g 0,2 g 0,0002 R06AX17 Ketotifen(O) 2,37 g 0,002 g 0,0025 R06AX22 Ebastine(O) 7019,3 g 0,01 g 1,4514 R06AX27 Desloratadine(O) 2180,54 g 0,005 g 0,9017 R06AX28 Rupatadine(O) 1049,64 g 0,01 g 0,2170 R06AX29 Bilastine(O) 17365,8 g 20 mg 1,7954 R07 OTHER RESPIRATORY SYSTEM PRODUCTS 0,0004 R07A OTHER RESPIRATORY SYSTEM PRODUCTS 0,0004 R07AA Lung surfactants 0,0004 R07AA81 Porcine lung phospholipids(endotrach) 30,36 g 0,16 g 0,0004 S SENSORY ORGANS 33,3145 S01 OPHTHALMOLOGICALS 33,3145 S01A ANTIINFECTIVES S01AA Antibiotics S01AA01 Chloramphenicol(S) 245840 ml S01AA02 Chlortetracycline(S) 1,25 g S01AA12 Tobramycin(S) 42815 ml S01AA12 Tobramycin(S) 54271 g S01AA13 Fusidic acid(S) 52300 g S01AD Antivirals S01AD02 Trifluridine(S) 5 ml S01AD03 Aciclovir(S) 3397,5 g S01AE Fluoroquinolones S01AE03 Ciprofloxacin(S) 18435 ml S01AE05 Levofloxacin(S) 26495 ml S01AE07 Moxifloxacin(S) 18080 ml S01AX Other antiinfectives S01AX18 Povidone, iodinated(S) 488 ml S01B ANTIINFLAMMATORY AGENTS S01BA Corticosteroids, plain S01BA01 Dexamethasone(S) 90 pieces S01BA01 Dexamethasone(S) 14680,3 g S01BA01 Dexamethasone(S) 156465 ml S01BA02 Hydrocortisone(S) 4143 g S01BA09 Clobetasone(S) 33500 ml S01BA14 Loteprednol(S) 6595 ml S01BC Antiinflammatory agents, non-steroids S01BC03 Diclofenac(S) 50 ml S01BC05 Ketorolac(S) 6500 ml S01BC10 Nepafenac(S) 20630 ml S01BC11 Bromfenac(S) 10470 ml
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
S01CA Corticosteroids and antiinfectives in combination S01CA80 Dexamethasone+Neomycin+Polymyxin B(S) 59170 ml S01CA81 Dexamethasone+Tobramycin(S) 15708 g S01CA81 Dexamethasone+Tobramycin(S) 43765 ml S01CA82 Dexamethasone+Chloramphenicol(S) 49059,5 g S01CA82 Dexamethasone+Chloramphenicol(S) 477140 ml S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS 33,3145 S01EA Sympathomimetics in glaucoma therapy 0,0183 S01EA05 Brimonidine(S) 1770 ml 0,2 ml 0,0183 S01EB Parasympathomimetics 0,0136 S01EB01 Pilocarpine(S) 2010 ml 0,4 ml 0,0104 S01EB02 Carbachol(S) 624 ml 0,4 ml 0,0032 S01EC Carbonic anhydrase inhibitors 3,7336 S01EC01 Acetazolamide(O) 25465 g 0,75 g 0,0702 S01EC01 Acetazolamide(P) 104,5 g 0,75 g 0,0003 S01EC03 Dorzolamide(S) 136500 ml 0,3 ml 0,9408
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Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day S01EC04 Brinzolamide(S) 162820 ml 0,2 ml 1,6833 S01EC80 Brinzolamide+Brimonidine(S) 100490 ml 0,2 ml 1,0389 S01ED Beta blocking agents 20,6756 S01ED01 Timolol(S) 23420 ml 0,2 ml 0,2421 S01ED01 Timolol(S) 219055 g 40 mg 11,3236 S01ED02 Betaxolol(S) 94910 ml 0,2 ml 0,9812 S01ED80 Timolol+Dorzolamide(S) 308050 ml 0,2 ml 3,1848 S01ED81 Timolol+Travoprost(S) 46380 ml 0,2 ml 0,4795 S01ED82 Timolol+Bimatoprost(S) 118551 ml 0,2 ml 1,2257 S01ED83 Timolol+Brinzolamide(S) 234105 ml 0,2 ml 2,4203 S01ED84 Timolol+Latanoprost(S) 72285 ml 0,2 ml 0,7473 S01ED85 Timolol+Tafluprost(S) 6869,7 ml 0,2 ml 0,0710 S01EE Prostaglandin analogues 8,8734 S01EE01 Latanoprost(S) 280272,5 ml 0,1 ml 5,7952 S01EE03 Bimatoprost(S) 255 ml 0,1 ml 0,0053 S01EE04 Travoprost(S) 73700 ml 0,1 ml 1,5239 S01EE05 Tafluprost(S) 224739 ml 0,3 ml 1,5490 S01F MYDRIATICS AND CYCLOPLEGICS S01FA Anticholinergics S01FA01 Atropine(S) 230 ml S01FA04 Cyclopentolate(S) 34620 ml S01FA06 Tropicamide(S) 17985 ml S01FB Sympathomimetics excl. antiglaucoma preparations S01FB01 Phenylephrine(S) 8595 ml S01G DECONGESTANTS AND ANTIALLERGICS S01GA Sympathomimetics used as decongestants S01GA02 Tetryzoline(S) 311940 ml S01GX Other antiallergics S01GX01 Cromoglicic acid(S) 117340 ml S01GX07 Azelastine(S) 40794 ml S01GX09 Olopatadine(S) 20210 ml S01H LOCAL ANESTHETICS S01HA Local anesthetics S01HA03 Tetracaine(S) 18280 ml S01HA04 Proxymetacaine(S) 46275 ml S01J DIAGNOSTIC AGENTS S01JA Colouring agents S01JA01 Fluorescein(P) 6120 ml S01JA81 Fluorescein+Oxybuprocaine+Chlorobutanol(S) 2825 ml S01K SURGICAL AIDS S01KA Viscoelastic substances S01KA02 Hypromellose(S) 5760 g S01L OCULAR VASCULAR DISORDER AGENTS S01LA Antineovascularisation agents S01LA01 Verteporfin(P) 3 pieces S01LA04 Ranibizumab(S) 4 pieces S01LA05 aflibercept(S) 228 pieces S01X OTHER OPHTHALMOLOGICALS S01XA Other ophthalmologicals S01XA03 Sodium chloride(S) 598,5 g S01XA18 Ciclosporin(S) 2484 ml S01XA80 Retinol+Dexpanthenol(S) 9457 g S01XA81 Carbomer(S) 191970 g S01XA82 Hypromellose(S) 195910 ml S01XA85 Hypromellose+Dextran(S) 457785 ml S02 OTOLOGICALS
S02C CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION
S02CA Corticosteroids and antiinfectives in combination S02CA81 Dexamethasone+Neomycin+Acetic acid, glacial(A) 3130 ml
39/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day S02CA82 Hydrocortisone+Ciprofloxacin(A) 134260 ml S02D OTHER OTOLOGICALS S02DA Analgesics and anesthetics S02DA81 Phenazone+Lidocaine(A) 1005 ml T HERBAL MEDICINAL PRODUCTS T01 HERBAL MEDICINAL PRODUCTS T01R HERBAL MEDICINAL PRODUCTS T01RS Herbal medicinal products T01RS01 herbal preparation(O) 716180 pieces T01RS01 herbal preparation(O) 8394970 ml T01RS02 homeopathic preparations(A) 7460 ml T01RS02 homeopathic preparations(C) 582550 g T01RS02 homeopathic preparations(O) 1540 g T01RS02 homeopathic preparations(O) 1194750 pieces T01RS02 homeopathic preparations(O) 1512010 ml V VARIOUS 0,2168 V01 ALLERGENS V01A ALLERGENS V01AA Allergen extracts V01AA02 Grass pollen(O) 136 pieces V01AA02 Grass pollen(P) 93 pieces V01AA03 House dust mites(O) 341 pieces V01AA03 House dust mites(P) 3 ml V01AA03 House dust mites(P) 258 pieces V01AA05 Tree pollen(P) 419 pieces V01AA05 Tree pollen(SL) 755 pieces V01AA07 Allergen products (insects)(P) 318 pieces V01AA10 Flowers(O) 7 pieces V01AA11 Animals(O) 29 pieces V01AA80 Tree and grass pollen(O) 162 pieces V01AA80 Tree and grass pollen(P) 57 pieces V01AA83 Grass pollen+Flowers(O) 24 pieces V01AA84 Tree and flower pollen(O) 33 pieces V03 ALL OTHER THERAPEUTIC PRODUCTS 0,2168 V03A ALL OTHER THERAPEUTIC PRODUCTS 0,2168 V03AB Antidotes V03AB14 Protamine sulfate(P) 275 g V03AB15 Naloxone(N) 1,8792 g V03AB15 Naloxone(P) 1,096 g V03AB16 Ethanol(P) 12500 ml V03AB17 Methylthioninium chloride(P) 157,5 g V03AB19 Physostigmine(P) 0,07 g V03AB24 Digitalis antitoxin(P) 1 g V03AB25 Flumazenil(P) 0,225 g V03AB33 Hydroxocobalamin(P) 40 g V03AB34 Fomepizole(P) 40 g V03AB35 Sugammadex(P) 66 g V03AB37 Idarucizumab(P) 225 g V03AC Iron chelating agents V03AC01 Deferoxamine(P) 7,5 g V03AC03 Deferasirox(O) 5929,2 g V03AE Drugs for treatment of hyperkalemia and hyperphosphatemia 0,1461 V03AE01 Polystyrene sulfonate(O, R) 1828723 g 45 g 0,0840 V03AE02 Sevelamer(O) 135792 g 6,4 g 0,0439 V03AE03 Lanthan(O) 19845 g 2,25 g 0,0182 V03AF Detoxifying agents for antineoplastic treatment 0,0707 V03AF01 Mesna(P) 5412 g V03AF03 Calcium folinate(O) 30,15 g 0,06 g 0,0010 V03AF07 Rasburicase(P) 0,6165 g 0,014 g 0,0001 V03AF09 Glucarpidase(P) 22000 U
40/41
Estonian Statistics on Medicines 2019
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day V03AF10 Sodium levofolinate(P) 1009,3 g 0,03 g 0,0696 V03AH Drugs for treatment of hypoglycemia V03AH01 Diazoxide(O) 55 g V03AN Medical gases V03AN01 Oxygen(I) 488368000 ml V03AN05 Air, medicinal(I) 2730000 ml V03AX Other therapeutic products V03AX01 Yohimbic acid(O) 0,25 g V04 DIAGNOSTIC AGENTS V04C OTHER DIAGNOSTIC AGENTS V04CD Tests for pituitary function V04CD01 Metyrapone(O) 12,5 g V04CD04 Corticorelin(P) 0,0002 g V04CF Tuberculosis diagnostics V04CF01 Tuberculin(P) 3600 U V04CJ Tests for thyreoidea function V04CJ02 Protirelin(P) 0,005 g V04CL Tests for allergic diseases V04CL83 Benzylpenicilloyl polylysine(P) 5 pieces V04CX Other diagnostic agents V04CX01 Indocyanine green(P) 6,625 g V04CX03 Methacholine(I) 45,036 g V04CX06 Hexaminolevulinate(P) 27,37 g V04CX09 Patent blue(P) 2,5 g V04CX87 Carbon monoxide+Helium(I) 20000 ml V07 ALL OTHER NON-THERAPEUTIC PRODUCTS V07A ALL OTHER NON-THERAPEUTIC PRODUCTS V07AB Solvents and diluting agents, incl. irrigating solutions V07AB80 Sodium chloride(P) 7171200 ml V07AB83 Water for injection(NA) 13359950 ml V08 CONTRAST MEDIA V08A X-RAY CONTRAST MEDIA, IODINATED
V08AA Watersoluble, nephrotropic, high osmolar X-ray contrast media
V08AA01 Sodium amidotrizoate+Meglumine Amidotrizoate(P) 6000 ml V08AB Watersoluble, nephrotropic, low osmolar X-ray contrast media V08AB02 Iohexol(P) 1748980 g V08AB05 Iopromide(P) 1216456,5 g V08AB09 Iodixanol(P) 2589464 g V08AD Non-watersoluble X-ray contrast media V08AD01 Ethyl esters of iodised fatty acids(P) 76,8 g V08B X-RAY CONTRAST MEDIA, NON-IODINATED V08BA Barium sulfate containing X-ray contrast media V08BA01 Barium sulfate(O) 151388,8 g V08BA01 Barium sulfate(O, R) 10400 g V08C MAGNETIC RESONANCE IMAGING CONTRAST MEDIA V08CA Paramagnetic contrast media V08CA01 Gadopentetic acid(P) 3520 ml V08CA02 Gadoteric acid(P) 47250 ml V08CA09 Gadobutrol(P) 80180 ml V08CA10 Gadoxetic acid(P) 4090 ml V08D ULTRASOUND CONTRAST MEDIA V08DA Ultrasound contrast media V08DA05 Sulfur hexafluoride, phospholipid microspheres(P) 200 ml V09 DIAGNOSTIC RADIOPHARMACEUTICALS V09A CENTRAL NERVOUS SYSTEM V09AB Iodine (123I) compounds V09AB03 Ioflupane (123I)(P) 175 ml
41/41
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A ALIMENTARY TRACT AND METABOLISM 195,7240
A01 STOMATOLOGICAL PREPARATIONS 0,0712
A01A STOMATOLOGICAL PREPARATIONS 0,0712
A01AA Caries prophylactic agents
A01AA01 Sodium fluoride (dental) 1 pieces
A01AB Antiinfectives and antiseptics for local oral treatment 0,0712
A01AB09 Miconazole (O) 6921,6 g 0,2 g 0,0712
A01AB12 Hexetidine (O) 631960 ml
A01AB82 Demeclocycline+ Triamcinolone (dental) 415 g
A01AD Other agents for local oral treatment
A01AD80 Lidocaine+ Cetylpyridinium chloride (gingival) 220680 g
A01AD81 Lidocaine+ Cetrimide (O) 67725 g
A01AD82 Choline salicylate (O) 648896 pieces
A01AD83 Lidocaine+ Chamomillae extractum (O) 379450 g
A02 DRUGS FOR ACID RELATED DISORDERS 66,8968
A02A ANTACIDS 1,3880
A02AD Combinations and complexes of aluminium, calcium and
magnesium compounds 1,3880
A02AD81 Aluminium hydroxide+ Magnesium hydroxide (O) 2198600 pieces 10 pieces 0,4522
A02AD81 Aluminium hydroxide+ Magnesium hydroxide (O) 5200710 ml 50 ml 0,2139
A02AD83 Calcium carbonate+ Magnesium carbonate (O) 3509592 pieces 10 pieces 0,7219
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-
OESOPHAGEAL REFLUX DISEASE (GORD) 65,5087
A02BA H2-receptor antagonists 0,0104
A02BA02 Ranitidine (P) 3,25 g 0,3 g <0,0001
A02BA03 Famotidine (O) 201,6 g 0,04 g 0,0104
A02BC Proton pump inhibitors 65,4802
A02BC01 Omeprazole (O) 313399,56 g 0,02 g 32,2308
A02BC02 Pantoprazole (O) 343352,52 g 0,04 g 17,6556
A02BC02 Pantoprazole (P) 12 g 0,04 g 0,0006
A02BC03 Lansoprazole (O) 15,12 g 0,03 g 0,0010
A02BC05 Esomeprazole (O) 219529,8 g 0,03 g 15,0513
A02BC05 Esomeprazole (P) 7887,6 g 0,03 g 0,5408
A02BC08 Vonoprazan (O) 2 g
A02BD Combinations for eradication of Helicobacter pylori 0,0031
A02BD08 Bismuth subcitrate+ Tetracycline+ Metronidazole (O) 18000 pieces 12 pieces 0,0031
A02BX Other drugs for peptic ulcer and gastro-oesophageal
reflux disease (GORD) 0,0151
A02BX02 Sucralfate (O) 29220 g 4 g 0,0150
A02BX05 Bismuth subcitrate (O) 6 g 0,48 g <0,0001
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL
DISORDERS 9,1480
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL
DISORDERS 8,1562
A03AA Synthetic anticholinergics, esters with tertiary amino
group 1,4403
A03AA04 Mebeverine (O) 210078 g 0,3 g 1,4403
A03AB Synthetic anticholinergics, quaternary ammonium
compounds 0,0002
A03AB02 Glycopyrronium (P) 0,028 g 0,3 mg 0,0002
A03AD Papaverine and derivatives 5,0731
A03AD01 Papaverine hydrochloride (P) 66,4 g 0,1 g 0,0014
A03AD02 Drotaverine (O) 243003,84 g 0,1 g 4,9982
A03AD02 Drotaverine (P) 3575 g 0,1 g 0,0735
A03AX Other drugs for functional gastrointestinal disorders 1,6426
A03AX13 Simeticone (O) 399293,125 g 0,5 g 1,6426
A03B BELLADONNA AND DERIVATIVES, PLAIN 0,0856
A03BA Belladonna alkaloids, tertiary amines 0,0739
1/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A03BA01 Atropine (O, P) 9,76 g 0,0015 g 0,0134
A03BA01 Atropine (P) 44,11 g 0,0015 g 0,0605
A03BB Belladonna alkaloids, semisynthetic, quaternary
ammonium compounds 0,0118
A03BB01 Hyoscine butylbromide (O) 8,4 g 0,06 g 0,0003
A03BB01 Hyoscine butylbromide (P) 335 g 0,06 g 0,0115
A03F PROPULSIVES 0,9061
A03FA Propulsives 0,9061
A03FA01 Metoclopramide (O) 11435 g 0,03 g 0,7840
A03FA01 Metoclopramide (P) 1568,4 g 0,03 g 0,1075
A03FA03 Domperidone (O) 212,4 g 0,03 g 0,0146
A04 ANTIEMETICS AND ANTINAUSEANTS 0,1376
A04A ANTIEMETICS AND ANTINAUSEANTS 0,1376
A04AA Serotonin (5-HT3) antagonists 0,1284
A04AA01 Ondansetron (P) 233,36 g 0,016 g 0,0300
A04AA02 Granisetron (O) 67 g 0,002 g 0,0689
A04AA02 Granisetron (P) 39,265 g 0,003 g 0,0269
A04AA80 Palonosetron+ Netupitant (O) 1235 pieces 1 pieces 0,0025
A04AD Other antiemetics 0,0092
A04AD01 Scopolamine (TD) 10 pieces 1 pieces <0,0001
A04AD12 Aprepitant (O) 190,095 g 0,165 g 0,0024
A04AD81 Fosaprepitant (P) 316,65 g 0,095 g 0,0069
A05 BILE AND LIVER THERAPY 1,8146
A05A BILE THERAPY 0,6209
A05AA Bile acids and derivatives 0,6209
A05AA02 Ursodeoxycholic acid (O) 226387,5 g 0,75 g 0,6209
A05B LIVER THERAPY, LIPOTROPICS 1,1937
A05BA Liver therapy 1,1937
A05BA03 Silymarin (O) 1886850 pieces
A05BA03 Silymarin (P) 28 g
A05BA80 Phospholipids from Soya Beans (O) 1017710 pieces 6 pieces 0,3489
A05BA80 Phospholipids from Soya Beans (O) 1232250 pieces 3 pieces 0,8449
A06 DRUGS FOR CONSTIPATION 17,9700
A06A DRUGS FOR CONSTIPATION 17,9700
A06AB Contact laxatives 7,5544
A06AB02 Bisacodyl (O) 14349,8 g 0,01 g 2,9515
A06AB02 Bisacodyl (R) 166,08 g 0,01 g 0,0342
A06AB06 Sennoside A (O) 460 pieces 1 pieces 0,0009
A06AB08 Sodium picosulfate (O) 11091,3849 g 0,005 g 4,5627
A06AB80 Sodium picosulfate+ Magnesium oxide+ Citric acid (O) 4922 pieces 2 pieces 0,0051
A06AD Osmotically acting laxatives 9,3124
A06AD11 Lactulose (O) 28355286 g 6,7 g 8,7049
A06AD15 Macrogol (O) 2953920 g 10 g 0,6076
A06AD80 Macrogol+ Sodium citrate+ Citric acid+ Sodium chloride+
Potassium chloride (O) 2400 ml
A06AD81 Sodium sulfate anhydrous+ Potassium chloride+ Sodium
chloride+ Macrogol+ Sodium hydrogen carbonate (O) 35656 pieces
A06AD83
Macrogol+ Sodium sulfate anhydrous+ Sodium chloride+
Potassium chloride+ Ascorbic acid+ Sodium ascorbate
(O)
7855 pieces
A06AD85 Sodium sulfate anhydrous+ magnesium sulfate
heptahydrate+ Potassium sulphate (O) 790944 ml
A06AG Enemas 1,0533
A06AG11 Sodium lauryl sulfoacetate+ Sorbitol+ Sodium citrate (R) 512116 pieces 1 pieces 1,0533
A06AH Peripheral opioid receptor antagonists 0,0497
A06AH03 Naloxegol (O) 603,75 g 25 mg 0,0497
A06AX Other drugs for constipation 0,0002
A06AX06 Tegaserod (O) 1,08 g 12 mg 0,0002
2/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A07 ANTIDIARRHEALS, INTESTINAL
ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS 4,9266
A07A INTESTINAL ANTIINFECTIVES 0,0082
A07AA Antibiotics 0,0082
A07AA02 Nystatin (O) 90000000 U 1500000 U 0,0001
A07AA11 Rifaximin (O) 2200,8 g 0,6 g 0,0075
A07AA12 Fidaxomicin (O) 108 g 0,4 g 0,0006
A07B INTESTINAL ADSORBENTS 0,5120
A07BC Other intestinal adsorbents 0,5120
A07BC05 Diosmectite (O) 2240220 g 9 g 0,5120
A07C ELECTROLYTES WITH CARBOHYDRATES
A07CA Oral rehydration salt formulations
A07CA80 Sodium chloride+ Potassium chloride+ Sodium citrate+
Glucose (O) 107820 pieces
A07D ANTIPROPULSIVES 1,0396
A07DA Antipropulsives 1,0396
A07DA03 Loperamide (O) 5054,564 g 0,01 g 1,0396
A07E INTESTINAL ANTIINFLAMMATORY AGENTS 2,5534
A07EA Corticosteroids acting locally 0,0319
A07EA06 Budesonide (O) 139,62 g 0,009 g 0,0319
A07EA06 Budesonide (R) 1,0619 g
A07EC Aminosalicylic acid and similar agents 2,5215
A07EC01 Sulfasalazine (O) 749300 g 2 g 0,7706
A07EC02 Mesalazine (O) 1167564 g 1,5 g 1,6010
A07EC02 Mesalazine (R) 109310 g 1,5 g 0,1499
A07F ANTIDIARRHEAL MICROORGANISMS 0,8134
A07FA Antidiarrheal microorganisms 0,8134
A07FA02 Saccharomyces boulardii (O) 395457,5 g 1 g 0,8134
A07X OTHER ANTIDIARRHEALS
A07XA Other antidiarrheals
A07XA04 Racecadotril (O) 2626 g
A08 ANTIOBESITY PREPARATIONS, EXCL. DIET
PRODUCTS 0,0035
A08A ANTIOBESITY PREPARATIONS, EXCL. DIET
PRODUCTS 0,0035
A08AA Centrally acting antiobesity products 0,0031
A08AA62 Bupropion+ Naltrexone (O) 6048 pieces 4 pieces 0,0031
A08AB Peripherally acting antiobesity products 0,0003
A08AB01 Orlistat (O) 60,48 g 0,36 g 0,0003
A09 DIGESTIVES, INCL. ENZYMES 1,8593
A09A DIGESTIVES, INCL. ENZYMES 1,8593
A09AA Enzyme preparations 1,8593
A09AA02 Lipase+ Amylase+ Protease (O) 3615886 pieces 4 pieces 1,8593
A10 DRUGS USED IN DIABETES 73,7920
A10A INSULINS AND ANALOGUES 15,9233
A10AB Insulins and analogues for injection, fast-acting 6,1766
A10AB01 Insulin human rapid-acting (P) 1054500 U 40 U 0,0542
A10AB04 Insulin lispro (P) 18876000 U 40 U 0,9706
A10AB05 Insulin aspart (P) 88759500 U 40 U 4,5641
A10AB06 Insulin glulisine (P) 11427000 U 40 U 0,5876
A10AC Insulins and analogues for injection, intermediate-acting 0,0421
A10AC01 Insulin human intermediate-acting (P) 819000 U 40 U 0,0421
A10AD Insulins and analogues for injection, intermediate- or long-
acting combined with fast-acting 0,7257
A10AD04 Insulin lispro (P) 2949000 U 40 U 0,1516
A10AD05 Insulin aspart (P) 7050000 U 40 U 0,3625
A10AD06 Insulin degludec+ Insulin aspart (P) 4114500 U 40 U 0,2116
A10AE Insulins and analogues for injection, long-acting 8,9789
A10AE04 Insulin glargine (P) 89067750 U 40 U 4,5800
A10AE05 Insulin detemir (P) 29962500 U 40 U 1,5407
3/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A10AE06 Insulin degludec (P) 52365300 U 40 U 2,6927
A10AE54 Insulin glargine+ Lixisenatide (P) 3219000 U 40 U 0,1655
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL.
INSULINS 57,8687
A10BA Biguanides 21,2384
A10BA02 Metformin (O) 20651358 g 2 g 21,2384
A10BB Sulfonylureas 10,7837
A10BB01 Glibenclamide (O) 0,054 g 0,01 g <0,0001
A10BB07 Glipizide (O) 650,85 g 0,01 g 0,1339
A10BB08 Gliquidone (O) 16,2 g 0,06 g 0,0006
A10BB09 Gliclazide (O) 179014,2 g 0,06 g 6,1368
A10BB12 Glimepiride (O) 4387,77 g 0,002 g 4,5125
A10BD Combinations of oral blood glucose lowering drugs 8,8691
A10BD07 Metformin+ Sitagliptin (O) 1368640 pieces 2 pieces 1,4075
A10BD08 Metformin+ Vildagliptin (O) 1349640 pieces 2 pieces 1,3880
A10BD10 Metformin+ Saxagliptin (O) 265920 pieces 2 pieces 0,2735
A10BD11 Metformin+ Linagliptin (O) 1351920 pieces 2 pieces 1,3903
A10BD15 Metformin+ Dapagliflozin (O) 1222648 pieces 2 pieces 1,2574
A10BD19 Linagliptin+ Empagliflozin (O) 292170 pieces 1 pieces 0,6010
A10BD20 Metformin+ Empagliflozin (O) 2272560 pieces 2 pieces 2,3372
A10BD21 Saxagliptin+ Dapagliflozin (O) 102928 pieces 1 pieces 0,2117
A10BD23 Metformin+ Ertugliflozin (O) 1232 pieces 1 pieces 0,0025
A10BF Alpha glucosidase inhibitors 0,0001
A10BF01 Acarbose (O) 21 g 0,3 g 0,0001
A10BG Thiazolidinediones 0,1191
A10BG03 Pioglitazone (O) 1737,54 g 0,03 g 0,1191
A10BH Dipeptyl peptidase 4 (DPP-4) inhibitors 4,2405
A10BH01 Sitagliptin (O) 35821,1 g 0,1 g 0,7368
A10BH02 Vildagliptin (O) 7689 g 0,1 g 0,1582
A10BH03 Saxagliptin (O) 448,65 g 5 mg 0,1846
A10BH05 Linagliptin (O) 7684,05 g 5 mg 3,1610
A10BJ Glucagon-like peptide-1 (GLP-1) analogues 7,1421
A10BJ01 Exenatide (P) 2,608 g 0,286 mg 0,0188
A10BJ02 Liraglutide (P) 350,892 g 1,5 mg 0,4812
A10BJ03 Lixisenatide (P) 0,3252 g 20 mcg 0,0334
A10BJ05 Dulaglutide (P) 50,31 g 0,16 mg 0,6468
A10BJ06 Semaglutide (O) 2953,74 g 10,5 mg 0,5786
A10BJ06 Semaglutide (P) 287,9 g 0,11 mg 5,3833
A10BK Sodium-glucose co-transporter 2 (SGLT2) inhibitors 5,4757
A10BK01 Dapagliflozin (O) 12969,45 g 10 mg 2,6676
A10BK03 empagliflozin (O) 23887,8 g 17,5 mg 2,8076
A10BK04 Ertugliflozin (O) 1,96 g 10 mg 0,0004
A11 VITAMINS 9,3214
A11A MULTIVITAMINS, COMBINATIONS 1,1303
A11AA Multivitamins with minerals 1,1303
A11AA03 Multivitamins+ Mineral elements (O) 549540 pieces 1 pieces 1,1303
A11C VITAMIN A AND D, INCL. COMBINATIONS OF THE
TWO 2,1840
A11CA Vitamin A, plain <0,0001
A11CA01 Retinol (P) 1200000 U 50000 U <0,0001
A11CC Vitamin D and analogues 2,1839
A11CC03 Alfacalcidol (O) 0,0003 g 0,001 mg 0,0007
A11CC04 Calcitriol (O) 0,0976 g 0,001 mg 0,2007
A11CC05 Colecalciferol (O) 771100000 U 800 U 1,9825
A11CC05 Colecalciferol (P) 65000000 U
A11D VITAMIN B1, PLAIN AND IN COMBINATION WITH
VITAMIN B6 AND B12 1,5661
A11DA Vitamin B1, plain 0,4634
A11DA01 Thiamine (P) 11264 g 0,05 g 0,4634
4/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A11DA03 Benfotiamine (O) 1759570 pieces
A11DB Vitamin B1 in combination with vitamin B6 and/or vitamin
B12 1,1027
A11DB80 Thiamine+ Pyridoxine (P) 5610 pieces 1 pieces 0,0115
A11DB81 Benfotiamine+ Pyridoxine (O) 216930 pieces 3 pieces 0,1487
A11DB84 Thiamine+ Pyridoxine+ Cyanocobalamin (O) 394660 pieces 1 pieces 0,8118
A11DB85 Thiamine+ Pyridoxine+ Cyanocobalamin+ Lidocaine (P) 63530 pieces 1 pieces 0,1307
A11E VITAMIN B-COMPLEX, INCL. COMBINATIONS 0,4422
A11EA Vitamin B-complex, plain 0,4422
A11EA80 Thiamine+ Nicotinamide+ Riboflavin+ Calcium
pantothenate+ Pyridoxine (O) 215000 pieces 1 pieces 0,4422
A11EA80 Thiamine+ Nicotinamide+ Riboflavin+ Calcium
pantothenate+ Pyridoxine (P) 552 pieces
A11G ASCORBIC ACID (VITAMIN C), INCL. COMBINATIONS 0,1701
A11GA Ascorbic acid (vitamin C), plain 0,1701
A11GA01 Ascorbic acid (P) 16535 g 0,2 g 0,1701
A11H OTHER PLAIN VITAMIN PREPARATIONS 0,0554
A11HA Other plain vitamin preparations 0,0554
A11HA02 Pyridoxine (O) 240 g 0,16 g 0,0031
A11HA02 Pyridoxine (P) 3829,5 g 0,16 g 0,0492
A11HA03 Tocopherol (P) 4,5 g 0,2 g <0,0001
A11HA05 Biotin (P) 12 ml
A11HA08 Tocofersolan (O) 294 g 0,2 g 0,0030
A11J OTHER VITAMIN PRODUCTS, COMBINATIONS 3,7734
A11JA Combinations of vitamins
A11JA80 Combinations of vitamins (O) 600 ml
A11JB Vitamins with minerals 3,7734
A11JB81 Pyridoxine+ Magnesium (O) 7338180 pieces 4 pieces 3,7734
A12 MINERAL SUPPLEMENTS 9,0667
A12A CALCIUM 5,4290
A12AA Calcium 0,9629
A12AA03 Calcium gluconate (P) 41340 g 3 g 0,0283
A12AA04 Calcium carbonate (O) 1363050 g 3 g 0,9345
A12AX Calcium, combinations with vitamin D and/or other drugs 4,4661
A12AX80 Calcium+ Colecalciferol (O) 577320 pieces 1 pieces 1,1875
A12AX80 Calcium+ Colecalciferol (O) 3188040 pieces 2 pieces 3,2787
A12B POTASSIUM 3,2030
A12BA Potassium 3,2030
A12BA01 Potassium chloride (O) 405066 g 3 g 0,2777
A12BA02 Potassium citrate (O) 1080 g 4 g 0,0006
A12BA80 Potassium chloride+ Potassium hydrogen carbonate (O) 4500 pieces
A12BA81 Potassium aspartate+ Magnesium aspartate (O) 4228100 pieces 3 pieces 2,8989
A12BA81 Potassium aspartate+ Magnesium aspartate (P) 12600 pieces 1 pieces 0,0259
A12C OTHER MINERAL SUPPLEMENTS 0,4346
A12CB Zinc
A12CB02 Zinc gluconate (P) 9,061 g
A12CC Magnesium 0,4345
A12CC04 Magnesium citrate (O) 422494 g 2 g 0,4345
A12CE Selenium 0,0001
A12CE02 Sodium selenite (P) 0,01 g 0,2 mg 0,0001
A12CX Other mineral products
A12CX83 Phosphate (O) 13500 pieces
A14 ANABOLIC AGENTS FOR SYSTEMIC USE 0,0044
A14A ANABOLIC STEROIDS 0,0044
A14AB Estren derivatives 0,0044
A14AB01 Nandrolone (P) 4,25 g 0,002 g 0,0044
5/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A16 OTHER ALIMENTARY TRACT AND METABOLISM
PRODUCTS 0,7120
A16A OTHER ALIMENTARY TRACT AND METABOLISM
PRODUCTS 0,7120
A16AA Amino acids and derivatives 0,0028
A16AA01 Levocarnitine (O) 1800 g 2 g 0,0019
A16AA02 Ademetionine (O) 810 g
A16AA05 Carglumic acid (O) 12 g 0,2 g 0,0001
A16AA06 Betaine (O) 2520 g 6 g 0,0009
A16AA81 Glycine (O) 480 g
A16AB Enzymes 0,0046
A16AB03 Agalsidase alfa (P) 1,316 g 0,001 g 0,0027
A16AB04 Agalsidase beta (P) 1,755 g 0,005 g 0,0007
A16AB07 Alglucosidase alfa (P) 54,7 g 0,1 g 0,0011
A16AB09 Idursulfase (P) 1,344 g
A16AX Various alimentary tract and metabolism products 0,7046
A16AX01 Thioctic acid (O) 201384 g 0,6 g 0,6904
A16AX01 Thioctic acid (P) 375 g 0,6 g 0,0013
A16AX05 Zinc (O) 650 g 0,15 g 0,0089
A16AX06 Miglustat (O) 218,4 g 0,3 g 0,0015
A16AX07 Sapropterin (O) 888 g
A16AX10 Eliglustat (O) 206,976 g 0,168 g 0,0025
A16AX80 Creatine (O) 6750 g
A16AX81 Copper histidinate (P) 0,19 g
B BLOOD AND BLOOD FORMING ORGANS 116,1519
B01 ANTITHROMBOTIC AGENTS 82,2564
B01A ANTITHROMBOTIC AGENTS 82,2564
B01AA Vitamin K antagonists 1,2187
B01AA03 Warfarin (O) 4443,8 g 0,0075 g 1,2187
B01AB Heparin group 3,1306
B01AB01 Heparin sodium (P) 567000000 U 10000 U 0,1166
B01AB05 Enoxaparin sodium (hem, P) 973076000 U 2000 U 1,0007
B01AB05 Enoxaparin sodium (P) 1896468000 U 2000 U 1,9504
B01AB12 Bemiparin sodium (P) 76365000 U 2500 U 0,0628
B01AC Platelet aggregation inhibitors, excl. heparin 51,8484
B01AC04 Clopidogrel (O) 146181,3 g 0,075 g 4,0090
B01AC06 Acetylsalicylic acid (O) 4753972 pieces 1 pieces 9,7782
B01AC09 Epoprostenol (P) 0,005 g
B01AC11 Iloprost (I) 0,0084 g 0,15 mg 0,0001
B01AC11 Iloprost (P) 0,0057 g 50 mcg 0,0002
B01AC16 Eptifibatide (P) 68,69 g 0,2 g 0,0007
B01AC21 Treprostinil (P) 7,82 g 0,0043 g 0,0037
B01AC23 Cilostazol (O) 84 g 0,2 g 0,0009
B01AC24 Ticagrelor (O) 102105,36 g 0,18 g 1,1668
B01AC27 Selexipag
(O) 1,932 g 1,8 mg 0,0022
B01AC80 Acetylsalicylic acid + Magnesium oxide (O) 17933500 pieces 1 pieces 36,8865
B01AD Enzymes 0,0030
B01AD01 Streptokinase (P) 135000000 U 1500000 U 0,0002
B01AD02 Alteplase (P) 116,4 g 0,1 g 0,0024
B01AD11 Tenecteplase (P) 8,11 g 0,04 g 0,0004
B01AE Direct thrombin inhibitors 2,5655
B01AE07 Dabigatran etexilate (O) 374190,6 g 0,3 g 2,5655
B01AF Direct factor Xa inhibitors 23,4886
B01AF01 Rivaroxaban (O) 108453,9088 g 0,02 g 11,1537
B01AF02 Apixaban (O) 51183,75 g 10 mg 10,5277
B01AF03 Edoxaban (O) 52718,4 g 60 mg 1,8072
B01AX Other antithrombotic agents 0,0016
B01AX01 Defibrotide (P) 8 g 1,75 g <0,0001
B01AX05 Fondaparinux sodium (P) 1,925 g 0,0025 g 0,0016
B02 ANTIHEMORRHAGICS 0,2310
6/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B02A ANTIFIBRINOLYTICS 0,2000
B02AA Amino acids 0,2000
B02AA01 Aminocaproic acid (P) 3430 g 16 g 0,0004
B02AA02 Tranexamic acid (O) 147200 g 2 g 0,1514
B02AA02 Tranexamic acid (P) 46800 g 2 g 0,0481
B02B VITAMIN K AND OTHER HEMOSTATICS 0,0310
B02BA Vitamin K 0,0032
B02BA01 Phytomenadione (O) 0,9 g 0,02 g 0,0001
B02BA01 Phytomenadione (O, P) 3,77 g 0,02 g 0,0004
B02BA01 Phytomenadione (P) 26,51 g 0,02 g 0,0027
B02BB Fibrinogen 0,0002
B02BB01 Fibrinogen human (P) 510 g 5 g 0,0002
B02BC Local hemostatics
B02BC81 Fibrinogen human+ Human thrombin (epil) 663 pieces
B02BD Blood coagulation factors
B02BD01 Human prothrombin complex (P) 247800 U
B02BD02 Human coagulation factor VIII (P) 7476000 U
B02BD03 Factor VIII inhibitor bypassing fraction (P) 45000 U
B02BD04 Human coagulation factor IX (P) 391200 U
B02BD05 Human coagulation factor VII (P) 370800 U
B02BD06 Von Willebrand factor+ Human coagulation factor VIII (P) 1516000 U
B02BD08 Coagulation factor VIIa (P) 77500000 U
B02BX Other systemic hemostatics 0,0276
B02BX01 Etamsylate (P) 382,5 g
B02BX04 Romiplostim (P) 0,089 g 30 mcg 0,0061
B02BX05 Eltrombopag (O) 394,1 g 50 mg 0,0162
B02BX06 Emicizumab (P) 38,685 g 15 mg 0,0053
B03 ANTIANEMIC PREPARATIONS 33,6611
B03A IRON PREPARATIONS 4,2823
B03AA Iron bivalent, oral preparations 1,9675
B03AA07 Ferrous sulfate (O) 191316 g 0,2 g 1,9675
B03AB Iron trivalent, oral preparations
B03AB80 Ferric hydroxide polymaltose complex (O) 86055 g
B03AC Iron, parenteral preparations 0,1386
B03AC01 Dextriferron (P) 2845,5 g 0,1 g 0,0585
B03AC02 Iron sucrose (P) 1587,5 g 0,1 g 0,0327
B03AC06 Iron (III)-hydroxide dextran complex (P) 1070,5 g 0,1 g 0,0220
B03AC80 Ferric derisomaltose (P) 1234 g 0,1 g 0,0254
B03AD Iron in combination with folic acid 2,1762
B03AD02 Ferrous fumarate+ Folic acid (O) 580380 pieces 1 pieces 1,1938
B03AD03 Ferrous sulfate+ Folic acid (O) 477650 pieces 1 pieces 0,9825
B03AE Iron in other combinations
B03AE81 Ferrous gluconate+ Manganese gluconate+ Copper
gluconate (O) 1510400 ml
B03AE82 Ferrous fumarate+ Folic acid+ Ascorbic acid (O) 75940 pieces
B03B VITAMIN B12 AND FOLIC ACID 28,4241
B03BA Vitamin B12 (cyanocobalamin and analogues) 8,2948
B03BA01 Cyanocobalamin (O) 17,15 g 1 mg 0,0353
B03BA01 Cyanocobalamin (P) 78,325 g 0,02 mg 8,0551
B03BA03 Hydroxocobalamin (P) 1,987 g 0,02 mg 0,2043
B03BB Folic acid and derivatives 20,1294
B03BB01 Folic acid (O) 3914,6 g 0,4 mg 20,1294
B03X OTHER ANTIANEMIC PREPARATIONS 0,9546
B03XA Other antianemic preparations 0,9546
B03XA01 Erythropoietin (P) 63663000 U 1000 U 0,1309
B03XA02 Darbepoetin alfa (P) 1,4903 g 0,0045 mg 0,6812
B03XA03 Methoxy polyethylene glycol-epoetin beta (P) 0,2772 g 4 mcg 0,1425
B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B05A BLOOD AND RELATED PRODUCTS
7/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B05AA Blood substitutes and plasma protein fractions
B05AA01 Albumin (P) 950202,5 g
B05AA06 Gelatin (P) 4030000 ml
B05AA83 Gelatin (anhydrous)+ Sodium chloride+ Potassium
chloride+ Magnesium chloride+ Sodium lactate (P) 380000 ml
B05AA86 human plasma protein (P) 491600 ml
B05B I.V. SOLUTIONS
B05BA Solutions for parenteral nutrition
B05BA01 Amino acids (P) 761000 ml
B05BA02 Fat emulsions (P) 144300 ml
B05BA03 Carbohydrates (P) 56765300 ml
B05BA10 Combinations (P) 17935741 ml
B05BB Solutions affecting the electrolyte balance
B05BB01 Electrolytes (P) 301979000 ml
B05BB02 Electrolytes+ Carbohydrates (P) 960000 ml
B05BB81 Sodium chloride+ Glucose (P) 290000 ml
B05BC Solutions producing osmotic diuresis
B05BC01 Mannitol (P) 846000 ml
B05C IRRIGATING SOLUTIONS
B05CX Other irrigating solutions
B05CX10 Combinations (NA) 16000 ml
B05D PERITONEAL DIALYTICS
B05DA Isotonic solutions
B05DA80 Isotonic solutions (P) 6080000 ml
B05DB Hypertonic solutions
B05DB80 hypertonic solutions (P) 127754000 ml
B05DB81
Amino acids+ Sodium chloride+ Calcium chloride
dihydrate+ Magnesium chloride hexahydrate+ Sodium
lactate (P)
370000 ml
B05Z HEMODIALYTICS AND HEMOFILTRATES
B05ZB Hemofiltrates
B05ZB80
Sodium chloride+ Potassium chloride+ Calcium chloride
dihydrate+ Magnesium chloride+ Glucose+ Sodium
hydrogen carbonate (P)
27530000 ml
B05ZB82
Calcium chloride dihydrate+ Magnesium chloride
hexahydrate+ Sodium chloride+ Sodium hydrogen
carbonate+ Potassium chloride+ Disodium phosphate
dihydrate (P)
8990000 ml
B05ZB83
Calcium chloride dihydrate+ Magnesium chloride
hexahydrate+ Glucose+ Lactic acid+ Sodium chloride+
Sodium hydrogen carbonate+ Potassium chloride (P)
200000 ml
B05ZB84
Calcium chloride dihydrate+ Magnesium chloride
hexahydrate+ Lactic acid+ Sodium hydrogen carbonate+
Sodium chloride (P)
150000 ml
B05ZB85 Sodium citrate+ Sodium chloride (P) 25000000 ml
B05ZB86
Magnesium chloride hexahydrate+ Sodium chloride+
Potassium chloride+ Disodium phosphate dihydrate+
Sodium hydrogen carbonate (P)
12120000 ml
B05X I.V. SOLUTION ADDITIVES
B05XA Electrolyte solutions
B05XA01 Potassium chloride (P) 750 g
B05XA01 Potassium chloride (P) 3346400 ml
B05XA02 Sodium hydrogen carbonate (P) 1627500 ml
B05XA03 Sodium chloride (P) 333459600 ml
B05XA05 Magnesium sulfate (P) 417900 ml
B05XA07 Calcium chloride (P) 515600 ml
B05XA14 Sodium glycerophosphate hydrate (P) 146000 ml
B05XA80 Electrolytes (P) 124800 ml
8/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B05XB Amino acids
B05XB01 Arginine (P) 3600 ml
B05XB02 Alanyl glutamine (P) 67000 ml
B05XC Vitamins
B05XC80 Vitamins (P) 8164,32 g
B05XC80 Vitamins (P) 109600 ml
B06 OTHER HEMATOLOGICAL AGENTS 0,0034
B06A OTHER HEMATOLOGICAL AGENTS 0,0034
B06AA Enzymes
B06AA03 Hyaluronidase (P) 135000 U
B06AB Heme products
B06AB01 Hemin (P) 120 ml
B06AC Drugs usedin hereditary angioedema 0,0034
B06AC01 C1-inhibitor, plasma derived (P) 137000 U 1400 U 0,0002
B06AC02 Icatibant (P) 5,34 g 0,03 g 0,0004
B06AC05 Lanadelumab (P) 29,4 g 21,4 mg 0,0028
C CARDIOVASCULAR SYSTEM 471,4739
C01 CARDIAC THERAPY 20,4066
C01A CARDIAC GLYCOSIDES 1,8085
C01AA Digitalis glycosides 1,8085
C01AA05 Digoxin (O) 217,98 g 0,25 mg 1,7934
C01AA05 Digoxin (P) 1,8325 g 0,25 mg 0,0151
C01B ANTIARRHYTHMICS, CLASS I AND III 4,9656
C01BA Antiarrhythmics, class Ia
C01BA13 Hydroquinidine (O) 162 g
C01BB Antiarrhythmics, class Ib 0,0211
C01BB02 Mexiletine (O) 198 g 0,8 g 0,0005
C01BB80 Ethacizine (O) 2000 g 0,2 g 0,0206
C01BC Antiarrhythmics, class Ic 3,3044
C01BC03 Propafenone (O) 446476,5 g 0,3 g 3,0611
C01BC03 Propafenone (P) 548,45 g 0,3 g 0,0038
C01BC04 Flecainide (O) 23248 g 0,2 g 0,2391
C01BC04 Flecainide (P) 41,25 g 0,2 g 0,0004
C01BD Antiarrhythmics, class III 1,6402
C01BD01 Amiodarone (O) 153240 g 0,2 g 1,5760
C01BD01 Amiodarone (P) 5013,75 g 0,2 g 0,0516
C01BD07 Dronedarone (O) 4920 g 0,8 g 0,0126
C01C CARDIAC STIMULANTS EXCL. CARDIAC
GLYCOSIDES 0,6961
C01CA Adrenergic and dopaminergic agents 0,6936
C01CA01 Etilefrine (O) 1,6875 g 0,05 g 0,0001
C01CA02 Isoprenaline (P) 0,732 g 0,09 g <0,0001
C01CA03 Norepinephrine (P) 352,6 g 0,006 g 0,1209
C01CA04 Dopamine (P) 1086 g 0,5 g 0,0045
C01CA06 Phenylephrine (P) 137,7 g 0,004 g 0,0708
C01CA07 Dobutamine (P) 1205 g 0,5 g 0,0050
C01CA17 Midodrine (O) 23,65 g 0,03 g 0,0016
C01CA24 Epinephrine (intraoss, P) 85,58 g 0,5 mg 0,3521
C01CA24 Epinephrine (P) 23,067 g 0,5 mg 0,0949
C01CA26 Ephedrine (P) 1066,5 g 0,05 g 0,0439
C01CE Phosphodiesterase inhibitors 0,0018
C01CE02 Milrinone (P) 43,08 g 0,05 g 0,0018
C01CX Other cardiac stimulants 0,0007
C01CX08 Levosimendan (P) 3,725 g 11 mg 0,0007
C01CX80 Ammonia (I) 1467400 ml
C01D VASODILATORS USED IN CARDIAC DISEASES 5,1316
C01DA Organic nitrates 5,1266
C01DA02 Glyceryl trinitrate (P) 183,8 g
C01DA02 Glyceryl trinitrate (SL) 443,552 g 0,0025 g 0,3649
C01DA08 Isosorbide dinitrate (O) 16 g 0,06 g 0,0005
C01DA08 Isosorbide dinitrate (SL) 186,9625 g 0,02 g 0,0192
9/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C01DA14 Isosorbide mononitrate (O) 92217 g 0,04 g 4,7419
C01DX Other vasodilatators used in cardiac diseases 0,0050
C01DX22 Vericiguat (O) 9,275 g 10 mg 0,0019
C01DX80 Meldonium (O) 1080 g 0,75 g 0,0030
C01DX80 Meldonium (P) 45 g 0,75 g 0,0001
C01E OTHER CARDIAC PREPARATIONS 7,8048
C01EA Prostaglandins 0,0002
C01EA01 Alprostadil (P) 0,0528 g 0,5 mg 0,0002
C01EB Other cardiac preparations 7,8045
C01EB10 Adenosine (P) 134,236 g 0,015 g 0,0184
C01EB15 Trimetazidine (O) 141180,9 g 0,04 g 7,2597
C01EB16 Ibuprofen (P) 0,84 g 0,03 g 0,0001
C01EB17 Ivabradine (O) 1973,72 g 0,01 g 0,4060
C01EB18 Ranolazine (O) 87022,5 g 1,5 g 0,1193
C01EB21 Regadenoson (P) 0,21 g 0,4 mg 0,0011
C01EB80 Hawthorn berries (O) 57600 ml
C02 ANTIHYPERTENSIVES 3,7688
C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING 2,3610
C02AC Imidazoline receptor agonists 2,3610
C02AC01 Clonidine (O) 5,19 g 0,45 mg 0,0237
C02AC01 Clonidine (P) 2,191 g 0,45 mg 0,0100
C02AC02 Guanfacine (O) 10,892 g 3 mg 0,0075
C02AC05 Moxonidine (O) 338,3454 g 0,3 mg 2,3198
C02C ANTIADRENERGIC AGENTS, PERIPHERALLY
ACTING 1,3641
C02CA Alpha-adrenoreceptor antagonists 1,3641
C02CA01 Prazosin (O) 0,48 g 0,005 g 0,0002
C02CA04 Doxazosin (O) 2652,492 g 0,004 g 1,3639
C02D ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING
ON 0,0013
C02DD Nitroferricyanide derivatives 0,0013
C02DD01 Sodium nitroprusside (P) 32 g 0,05 g 0,0013
C02K OTHER ANTIHYPERTENSIVES 0,0424
C02KX Antihypertensives for pulmonary arterial hypertension 0,0424
C02KX01 Bosentan (O) 1617 g 0,25 g 0,0133
C02KX02 Ambrisentan (O) 45,45 g 7,5 mg 0,0125
C02KX04 Macitentan (O) 17,1 g 10 mg 0,0035
C02KX05 Riociguat (O) 28,686 g 4,5 mg 0,0131
C03 DIURETICS 26,7824
C03A LOW-CEILING DIURETICS, THIAZIDES 1,0887
C03AA Thiazides, plain 1,0887
C03AA03 Hydrochlorothiazide (O) 13232 g 0,025 g 1,0887
C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES 2,0716
C03BA Sulfonamides, plain 2,0716
C03BA11 Indapamide (O) 2517,87 g 2,5 mg 2,0716
C03C HIGH-CEILING DIURETICS 19,7813
C03CA Sulfonamides, plain 19,7813
C03CA01 Furosemide (O) 57214,6 g 0,04 g 2,9420
C03CA01 Furosemide (P) 5362,6 g 0,04 g 0,2758
C03CA04 Torasemide (O) 120451,65 g 0,015 g 16,5167
C03CA04 Torasemide (P) 341 g 0,015 g 0,0468
C03D ALDOSTERONE ANTAGONISTS AND OTHER
POTASSIUM-SPARING AGENTS 3,8316
C03DA Aldosterone antagonists 3,8300
C03DA01 Spironolactone (O) 139332,75 g 0,075 g 3,8212
C03DA04 Eplerenone (O) 214,5 g 0,05 g 0,0088
C03DB Other potassium-sparing agents 0,0016
C03DB01 Amiloride (O) 7,96 g 10 mg 0,0016
C03E DIURETICS AND POTASSIUM-SPARING AGENTS IN
COMBINATION 0,0093
10/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C03EA Low-ceiling diuretics and potassium-sparing agents 0,0093
C03EA81 Hydrochlorothiazide+ Amiloride (O) 4530 pieces 1 pieces 0,0093
C04 PERIPHERAL VASODILATORS 2,5208
C04A PERIPHERAL VASODILATORS 2,5208
C04AC Nicotinic acid and derivatives 0,0001
C04AC01 Nicotinic acid (P) 5 g 0,2 g 0,0001
C04AD Purine derivatives 1,3867
C04AD02 Xantinol nicotinate (O) 18 g 0,9 g <0,0001
C04AD03 Pentoxifylline (O) 673088 g 1 g 1,3844
C04AD03 Pentoxifylline (P) 320,5 g 0,3 g 0,0022
C04AX Other peripheral vasodilators 1,1341
C04AX21 Naftidrofuryl (O) 330830 g 0,6 g 1,1341
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND
ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA82 Hydrocortisone+ Cinchocaine (R) 11940 pieces
C05AA84 Fluocortolone+ Lidocaine (R) 197175 g
C05AA84 Fluocortolone+ Lidocaine (R) 241850 pieces
C05AE Muscle relaxants
C05AE01 Glyceryl trinitrate (R) 150 g
C05AX Other agents for treatment of hemorrhoids and anal
fissures for topical use
C05AX81 Xeroformium+ Zinc sulphate+ Belladonna extract (R) 1930 pieces
C05AX83 Yeast extract+ Shark-liver oil (R) 279504 pieces
C05B ANTIVARICOSE THERAPY
C05BA Heparins or heparinoids for topical use
C05BA03 Heparin sodium (C) 7213550 g
C05BB Sclerosing agents for local injection
C05BB02 Lauromacrogol 400 (P) 91,8 g
C05C CAPILLARY STABILIZING AGENTS
C05CA Bioflavonoids
C05CA01 Rutoside (O) 272115 pieces
C05CA03 Diosmin (O) 475890 g
C05CA04 Troxerutin (C) 3637200 g
C05CA04 Troxerutin (O) 198885 g
C05CA53 Diosmin+ Hesperidin (O) 618930 pieces
C07 BETA BLOCKING AGENTS 58,5134
C07A BETA BLOCKING AGENTS 58,5127
C07AA Beta blocking agents, non-selective 1,5825
C07AA05 Propranolol (O) 56299 g 0,16 g 0,7237
C07AA07 Sotalol (O) 66800 g 0,16 g 0,8587
C07AB Beta blocking agents, selective 56,3160
C07AB02 Metoprolol (O) 2046374,6 g 0,15 g 28,0606
C07AB02 Metoprolol (P) 113,05 g 0,15 g 0,0016
C07AB03 Atenolol (O) 14983,5 g 0,075 g 0,4109
C07AB07 Bisoprolol (O) 21413,65 g 0,01 g 4,4045
C07AB09 Esmolol (P) 10 g 2,5 g <0,0001
C07AB12 Nebivolol (O) 56976,51 g 0,005 g 23,4384
C07AG Alpha and beta blocking agents 0,6142
C07AG01 Labetalol (O) 32105 g 0,6 g 0,1101
C07AG01 Labetalol (P) 1364,5 g 0,6 g 0,0047
C07AG02 Carvedilol (O) 9106,6875 g 0,0375 g 0,4995
C07B BETA BLOCKING AGENTS AND THIAZIDES 0,0007
C07BB Beta blocking agents, selective, and thiazides 0,0007
C07BB81 Bisoprolol+ Hydrochlorothiazide (O) 360 pieces 1 pieces 0,0007
C08 CALCIUM CHANNEL BLOCKERS 43,0355
C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH
MAINLY VASCULAR EFFECTS 41,6952
11/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C08CA Dihydropyridine derivatives 41,6952
C08CA01 Amlodipine (O) 62736,3 g 0,005 g 25,8078
C08CA02 Felodipine (O) 4549,725 g 0,005 g 1,8716
C08CA05 Nifedipine (O) 11833 g 0,03 g 0,8113
C08CA06 Nimodipine (O) 450 g 0,3 g 0,0031
C08CA06 Nimodipine (P) 0,98 g 0,05 g <0,0001
C08CA08 Nitrendipine (O) 36134,3 g 0,02 g 3,7161
C08CA09 Lacidipine (O) 4599,392 g 0,004 g 2,3651
C08CA13 Lercanidipine (O) 34616,7 g 0,01 g 7,1201
C08D SELECTIVE CALCIUM CHANNEL BLOCKERS WITH
DIRECT CARDIAC EFFECTS 1,3402
C08DA Phenylalkylamine derivatives 1,2019
C08DA01 Verapamil (O) 140242 g 0,24 g 1,2019
C08DA01 Verapamil (P) 4,775 g 0,24 g <0,0001
C08DB Benzothiazepine derivatives 0,1383
C08DB01 Diltiazem (O) 16137 g 0,24 g 0,1383
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN
SYSTEM 213,9459
C09A ACE INHIBITORS, PLAIN 74,6606
C09AA ACE inhibitors, plain 74,6606
C09AA01 Captopril (O) 2,5 g 0,05 g 0,0001
C09AA02 Enalapril (O) 31966,21 g 0,01 g 6,5750
C09AA02 Enalapril (P) 9,9125 g 0,01 g 0,0020
C09AA03 Lisinopril (O) 2,24 g 0,01 g 0,0005
C09AA04 Perindopril (O) 20142,33 g 0,004 g 10,3574
C09AA05 Ramipril (O) 65743,26 g 2,5 mg 54,0896
C09AA09 Fosinopril (O) 25796,96 g 0,015 g 3,5374
C09AA10 Trandolapril (O) 95,816 g 0,002 g 0,0985
C09B ACE INHIBITORS, COMBINATIONS 59,6075
C09BA ACE inhibitors and diuretics 28,4169
C09BA02 Enalapril+ Hydrochlorothiazide (O) 2273684 pieces 1 pieces 4,6766
C09BA04 Perindopril+ Indapamide (O) 10032510 pieces 1 pieces 20,6354
C09BA05 Ramipril+ Hydrochlorothiazide (O) 1030652 pieces 1 pieces 2,1199
C09BA06 Quinapril+ Hydrochlorothiazide (O) 100 pieces 1 pieces 0,0002
C09BA09 Fosinopril+ Hydrochlorothiazide (O) 478790 pieces 1 pieces 0,9848
C09BB ACE inhibitors and calcium channel blockers 13,5294
C09BB03 Lisinopril+ Amlodipine (O) 738570 pieces 1 pieces 1,5191
C09BB04 Perindopril+ Amlodipine (O) 4938660 pieces 1 pieces 10,1581
C09BB07 Ramipril+ Amlodipine (O) 671520 pieces 1 pieces 1,3812
C09BB10 Trandolapril+ Verapamil (O) 228956 pieces 1 pieces 0,4709
C09BX ACE inhibitors, other combinations 17,6612
C09BX01 Perindopril+ Amlodipine+ Indapamide (O) 8586510 pieces 1 pieces 17,6612
C09C ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS),
PLAIN 44,5999
C09CA Angiotensin II receptor blockers (ARBs), plain 44,5999
C09CA01 Losartan (O) 82226 g 0,05 g 3,3825
C09CA02 Eprosartan (O) 428,4 g 0,6 g 0,0015
C09CA03 Valsartan (O) 168660,8 g 0,08 g 4,3364
C09CA06 Candesartan (O) 43007,36 g 0,008 g 11,0575
C09CA07 Telmisartan (O) 430595,2 g 0,04 g 22,1418
C09CA08 Olmesartan medoxomil (O) 35785,96 g 0,02 g 3,6803
C09D ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS),
COMBINATIONS 35,0780
C09DA Angiotensin II receptor blockers (ARBs) and diuretics 14,7274
C09DA80 Losartan+ Hydrochlorothiazide (O) 766910 pieces 1 pieces 1,5774
C09DA82 Valsartan+ Hydrochlorothiazide (O) 858256 pieces 1 pieces 1,7653
C09DA84 Candesartan+ Hydrochlorothiazide (O) 1143214 pieces 1 pieces 2,3514
C09DA85 Telmisartan+ Hydrochlorothiazide (O) 4088276 pieces 1 pieces 8,4090
C09DA86 Olmesartan medoxomil+ Hydrochlorothiazide (O) 303510 pieces 1 pieces 0,6243
12/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C09DB Angiotensin II receptor blockers (ARBs) and calcium
channel blockers 14,3702
C09DB01 Valsartan+ Amlodipine (O) 248708 pieces 1 pieces 0,5116
C09DB02 Olmesartan medoxomil+ Amlodipine (O) 3382120 pieces 1 pieces 6,9565
C09DB04 Telmisartan+ Amlodipine (O) 3285912 pieces 1 pieces 6,7586
C09DB07 Candesartan+ Amlodipine (O) 69776 pieces 1 pieces 0,1435
C09DX Angiotensin II receptor blockers (ARBs), other
combinations 5,9803
C09DX01 Valsartan+ Amlodipine+ Hydrochlorothiazide (O) 4900 pieces 1 pieces 0,0101
C09DX03 Olmesartan medoxomil+ Amlodipine+
Hydrochlorothiazide (O) 2446584 pieces 1 pieces 5,0323
C09DX04 Valsartan+ Sacubitril (O) 456036 pieces 1 pieces 0,9380
C10 LIPID MODIFYING AGENTS 102,5003
C10A LIPID MODIFYING AGENTS, PLAIN 97,8034
C10AA HMG CoA reductase inhibitors 96,0396
C10AA01 Simvastatin (O) 57078,8 g 0,03 g 3,9134
C10AA03 Pravastatin (O) 3542,4 g 0,03 g 0,2429
C10AA04 Fluvastatin (O) 13496 g 0,06 g 0,4627
C10AA05 Atorvastatin (O) 378967,5 g 0,02 g 38,9740
C10AA07 Rosuvastatin (O) 254984,95 g 0,01 g 52,4466
C10AB Fibrates 0,7583
C10AB02 Bezafibrate (O) 20 g 0,6 g 0,0001
C10AB05 Fenofibrate (O) 73728 g 0,2 g 0,7582
C10AC Bile acid sequestrants 0,0029
C10AC01 Colestyramine (O) 19600 g 14 g 0,0029
C10AX Other lipid modifying agents 1,0027
C10AX09 Ezetimibe (O) 4601,04 g 0,01 g 0,9464
C10AX13 Evolocumab (P) 172,2 g 10 mg 0,0354
C10AX14 Alirocumab (P) 17,55 g 5,4 mg 0,0067
C10AX16 Inclisiran (P) 11,076 g 1,6 mg 0,0142
C10AX80 Omega-3-acid ethyl esters 90 (O) 220276 pieces
C10B LIPID MODIFYING AGENTS, COMBINATIONS 4,6969
C10BA Combinations of various lipid modifying agents 3,9577
C10BA05 Atorvastatin+ Ezetimibe (O) 198690 pieces 1 pieces 0,4087
C10BA06 Rosuvastatin+ Ezetimibe (O) 1725450 pieces 1 pieces 3,5490
C10BX Lipid modifying agents in combination with other drugs 0,7392
C10BX11 Atorvastatin+ Amlodipine+ Perindopril (O) 203790 pieces 1 pieces 0,4192
C10BX13 Rosuvastatin+ Perindopril+ Indapamide (O) 139170 pieces 1 pieces 0,2863
C10BX15 Atorvastatin+ Perindopril (O) 16440 pieces 1 pieces 0,0338
D DERMATOLOGICALS 1,8433
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE 1,0176
D01A ANTIFUNGALS FOR TOPICAL USE
D01AC Imidazole and triazole derivatives
D01AC01 Clotrimazole (C) 100 ml
D01AC01 Clotrimazole (C) 1021990 g
D01AC05 Isoconazole (C) 276240 g
D01AC08 Ketoconazole (C) 559545 g
D01AC08 Ketoconazole (C) 2699160 ml
D01AC80 Isoconazole+ Diflucortolone (C) 793875 g
D01AC81 Clotrimazole+ Hexamidine (C) 128790 g
D01AE Other antifungals for topical use
D01AE14 Ciclopirox (C) 630,3 ml
D01AE15 Terbinafine (C) 57849 ml
D01AE15 Terbinafine (C) 494104 g
D01AE16 Amorolfine (C) 26380 ml
D01AE22 Naftifine (C) 141350 ml
D01AE22 Naftifine (C) 205380 g
D01B ANTIFUNGALS FOR SYSTEMIC USE 1,0176
D01BA Antifungals for systemic use 1,0176
D01BA01 Griseofulvin (O) 372,5 g 0,5 g 0,0015
13/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D01BA02 Terbinafine (O) 123493 g 0,25 g 1,0160
D02 EMOLLIENTS AND PROTECTIVES
D02A EMOLLIENTS AND PROTECTIVES
D02AB Zinc products
D02AB80 Zinc oxide (C) 240 g
D02B PROTECTIVES AGAINST UV-RADIATION
D02BA Protectives against UV-radiation for topical use
D02BA01 4-aminobenzoic acid (O) 360 g
D03 PREPARATIONS FOR TREATMENT OF WOUNDS AND
ULCERS
D03A CICATRIZANTS
D03AX Other cicatrizants
D03AX03 Dexpanthenol (C) 4025870 g
D03AX81 Heparin sodium+ Allantoin+ Extractum Cepae (C) 130500 g
D03AX83 Dexpanthenol+ Chlorhexidine (C) 2213190 g
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES,
ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES,
ANESTHETICS, ETC.
D04AA Antihistamines for topical use
D04AA13 Dimetindene (C) 37,74 g
D05 ANTIPSORIATICS 0,0540
D05A ANTIPSORIATICS FOR TOPICAL USE
D05AA Tars
D05AA85 Coal tar+ Salicylic acid (C) 794000 ml
D05AX Other antipsoriatics for topical use
D05AX80 Calcipotriol+ Betamethasone (C) 1064700 g
D05B ANTIPSORIATICS FOR SYSTEMIC USE 0,0540
D05BB Retinoids for treatment of psoriasis 0,0540
D05BB02 Acitretin (O) 919,2 g 0,035 g 0,0540
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR
DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE
D06AX Other antibiotics for topical use
D06AX01 Fusidic acid (C) 243465 g
D06AX09 Mupirocin (C) 2520 g
D06AX80 Bacitracin+ Neomycin (C) 83970 g
D06AX84 Chloramphenicol+ Methyluracil (C) 800 g
D06B CHEMOTHERAPEUTICS FOR TOPICAL USE
D06BA Sulfonamides
D06BA01 Sulfadiazine silver (C) 1466760 g
D06BB Antivirals
D06BB03 Aciclovir (C) 207002 g
D06BB04 Podophyllotoxin (C) 1638 ml
D06BB10 Imiquimod (C) 5679 g
D06BB81 Aciclovir+ Hydrocortisone (C) 28420 g
D06BX Other chemotherapeutics
D06BX01 Metronidazole (C) 162010 g
D07 CORTICOSTEROIDS, DERMATOLOGICAL
PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AA Corticosteroids, weak (group I)
D07AA02 Hydrocortisone (C) 608910 g
D07AB Corticosteroids, moderately potent (group II)
D07AB09 Triamcinolone (C) 355 g
D07AC Corticosteroids, potent (group III)
D07AC01 Betamethasone (C) 114600 g
D07AC04 Fluocinolone acetonide (C) 210 g
D07AC13 Mometasone (C) 332160 ml
D07AC13 Mometasone (C) 1201835 g
D07AC14 Methylprednisolone aceponate (C) 594265 g
14/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D07AC17 Fluticasone (C) 38415 g
D07AD Corticosteroids, very potent (group IV)
D07AD01 Clobetasol (C) 88400 ml
D07AD01 Clobetasol (C) 953175 g
D07B CORTICOSTEROIDS, COMBINATIONS WITH
ANTISEPTICS
D07BA Corticosteroids, weak, combinations with antiseptics
D07BA80 Hydrocortisone+ Chlorhexidine (C) 342860 g
D07BC Corticosteroids, potent, combinations with antiseptics
D07BC80 Betamethasone+ Salicylic acid (C) 26270 g
D07BC80 Betamethasone+ Salicylic acid (C) 977530 ml
D07C CORTICOSTEROIDS, COMBINATIONS WITH
ANTIBIOTICS
D07CA Corticosteroids, weak, combinations with antibiotics
D07CA83 Hydrocortisone+ Fusidic acid (C) 85050 g
D07CC Corticosteroids, potent, combinations with antibiotics
D07CC80 Betamethasone+ Fusidic acid (C) 597240 g
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XA Corticosteroids, weak, other combinations
D07XA81 Prednisolone+ Salicylic acid (C) 252700 ml
D08 ANTISEPTICS AND DISINFECTANTS
D08A ANTISEPTICS AND DISINFECTANTS
D08AG Iodine products
D08AG02 Povidone, iodinated (C) 1172310 ml
D08AG02 Povidone, iodinated (C) 3907170 g
D08AG03 Iodine (C) 1166820 ml
D08AJ Quaternary ammonium compounds
D08AJ81 Octenidine+ Phenoxyethanol (C) 12072850 ml
D08AX Other antiseptics and disinfectants
D08AX82 Tar blend+ Castor oil+ Xeroformium (C) 9730 g
D08AX83 Brilliant Green (C) 289230 ml
D10 ANTI-ACNE PREPARATIONS 0,5991
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AD Retinoids for topical use in acne
D10AD01 Tretinoin (C) 55290 g
D10AD03 Adapalene (C) 78180 g
D10AD80 Adapalene+ Benzoyl peroxide (C) 64170 g
D10AD81 Tretinoin+ Erythromycin (C) 42240 g
D10AF Antiinfectives for treatment of acne
D10AF01 Clindamycin (C) 33300 ml
D10AF02 Erythromycin (C) 368000 ml
D10AF81 Clindamycin+ Benzoyl peroxide (C) 211215 g
D10AF82 Clindamycin+ Tretinoin (C) 139560 g
D10AX Other anti-acne preparations for topical use
D10AX03 Azelaic acid (C) 340920 g
D10B ANTI-ACNE PREPARATIONS FOR SYSTEMIC USE 0,5991
D10BA Retinoids for treatment of acne 0,5991
D10BA01 Isotretinoin (O) 8738,1 g 0,03 g 0,5991
D11 OTHER DERMATOLOGICAL PREPARATIONS 0,1726
D11A OTHER DERMATOLOGICAL PREPARATIONS 0,1726
D11AF Wart and anti-corn preparations
D11AF80 Salicylic acid+ Lactic acid (C) 89070 ml
D11AH Agents for dermatitis, excluding corticosteroids 0,0720
D11AH01 Tacrolimus (C) 119010 g
D11AH02 Pimecrolimus (C) 250275 g
D11AH05 Dupilumab (P) 748,6 g 21,4 mg 0,0720
D11AX Other dermatologicals 0,1007
15/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D11AX01 Minoxidil (C) 158160 ml
D11AX10 Finasteride (O) 48,944 g 0,001 g 0,1007
D11AX16 Eflornithine (C) 390 g
D11AX21 Brimonidine (C) 30 g
D11AX22 Ivermectin (C) 28650 g
G GENITO URINARY SYSTEM AND SEX HORMONES 58,2519
G01 GYNECOLOGICAL ANTIINFECTIVES AND
ANTISEPTICS 0,8455
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL.
COMBINATIONS WITH CORTICOSTEROIDS 0,8455
G01AA Antibiotics 0,0231
G01AA10 Clindamycin (V) 1123,5 g 0,1 g 0,0231
G01AA80 Nystatin+ Neomycin+ Polymyxin B (V) 12 pieces
G01AC Quinoline derivatives 0,0533
G01AC05 Dequalinium (V) 517,8 g 20 mg 0,0533
G01AF Imidazole derivatives 0,7692
G01AF01 Metronidazole (V) 14338 g 0,5 g 0,0590
G01AF02 Clotrimazole (V) 28079,7 g 0,1 g 0,5776
G01AF05 Econazole (V) 4839,3 g 0,1 g 0,0995
G01AF12 Fenticonazole (V) 1609,8 g 0,1 g 0,0331
G02 OTHER GYNECOLOGICALS 3,9212
G02A UTEROTONICS 0,0925
G02AB Ergot alkaloids 0,0022
G02AB01 Methylergometrine (P) 0,2112 g 0,2 mg 0,0022
G02AD Prostaglandins 0,0903
G02AD02 Dinoprostone (P) 0,08 g
G02AD02 Dinoprostone (V) 1,6123 g 0,5 mg 0,0066
G02AD06 Misoprostol (O) 8,1368 g 0,2 mg 0,0837
G02B CONTRACEPTIVES FOR TOPICAL USE 2,2513
G02BA Intrauterine contraceptives
G02BA03 Levonorgestrel (V) 8881 pieces
G02BB Intravaginal contraceptives 2,2513
G02BB01 Etonogestrel+ Ethinylestradiol (V) 38281 pieces 0,036 pieces 2,1872
G02BB81 Benzalkonium chloride (V) 14688 g
G02BB81 Benzalkonium chloride (V) 31170 pieces 1 pieces 0,0641
G02C OTHER GYNECOLOGICALS 1,5775
G02CA Sympathomimetics, labour repressants
G02CA80 Hexoprenaline (P) 0,0205 g
G02CB Prolactine inhibitors 0,1421
G02CB01 Bromocriptine (O) 264,3 g 0,005 g 0,1087
G02CB03 Cabergoline (O) 8,116 g 0,5 mg 0,0334
G02CX Other gynecologicals 1,4353
G02CX01 Atosiban (P) 1,3125 g 0,165 g <0,0001
G02CX03 Agnus castus fruit (O) 380400 pieces 1 pieces 0,7824
G02CX04 Cimicifugae rhizoma (O) 634860 pieces 2 pieces 0,6529
G03 SEX HORMONES AND MODULATORS OF THE
GENITAL SYSTEM 31,0067
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE 23,5400
G03AA Progestogens and estrogens, fixed combinations 18,1700
G03AA07 Levonorgestrel+ Ethinylestradiol (O) 218596 pieces 1 pieces 0,4496
G03AA09 Desogestrel+ Ethinylestradiol (O) 335538 pieces 0,75 pieces 0,9202
G03AA10 Gestodene+ Ethinylestradiol (O) 1933596 pieces 0,75 pieces 5,3028
G03AA12 Drospirenone+ Ethinylestradiol (O) 1162336 pieces 1 pieces 2,3908
G03AA12 Drospirenone+ Ethinylestradiol (O) 1547847 pieces 0,75 pieces 4,2449
G03AA13 Norelgestromin+ Ethinylestradiol (TD) 85920 pieces 0,107 pieces 1,6516
G03AA14 Nomegestrol+ Estradiol (O) 32368 pieces 1 pieces 0,0666
G03AA15 Chlormadinone+ Ethinylestradiol (O) 141876 pieces 0,75 pieces 0,3891
G03AA16 Dienogest+ Ethinylestradiol (O) 1004353 pieces 0,75 pieces 2,7544
G03AB Progestogens and estrogens, sequential preparations 0,1977
16/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G03AB05 Desogestrel+ Ethinylestradiol (O) 1782 pieces 0,75 pieces 0,0049
G03AB08 Dienogest+ Estradiol valerate (O) 93744 pieces 1 pieces 0,1928
G03AC Progestogens 5,0841
G03AC08 Etonogestrel (P) 63,512 g 68 mcg 1,9211
G03AC09 Desogestrel (O) 1298416 pieces 1 pieces 2,6706
G03AC10 Drospirenone (O) 239372 pieces 1 pieces 0,4924
G03AD Emergency contraceptives 0,0882
G03AD01 Levonorgestrel (O) 62,5815 g 1,5 mg 0,0858
G03AD02 Ulipristal (O) 34,29 g 0,03 g 0,0024
G03B ANDROGENS 0,2661
G03BA 3-oxoandrosten (4) derivatives 0,2661
G03BA03 Testosterone (C) 34,5 g 0,05 g 0,0014
G03BA03 Testosterone (O) 7,2 g 0,12 g 0,0001
G03BA03 Testosterone (P) 2315,25 g 0,018 g 0,2646
G03C ESTROGENS 1,6245
G03CA Natural and semisynthetic estrogens, plain 1,6121
G03CA03 Estradiol (C, V) 6,835 g
G03CA03 Estradiol (O) 863,324 g 2 mg 0,8879
G03CA03 Estradiol (TD) 35,3002 g 1,53 mg 0,0475
G03CA03 Estradiol (TD) 126,056 g 1 mg 0,2593
G03CA03 Estradiol (V) 3,0829 g 0,025 mg 0,2536
G03CA04 Estriol (V) 15,9375 g 0,2 mg 0,1639
G03CA80 Estradiol+ Prednisolone (C) 50025 g
G03CX Other estrogens 0,0123
G03CX01 Tibolone (O) 14,98 g 2,5 mg 0,0123
G03D PROGESTOGENS 2,4532
G03DA Pregnen (4) derivatives 1,6745
G03DA02 Medroxyprogesterone (O) 119,55 g 0,005 g 0,0492
G03DA02 Medroxyprogesterone (P) 211,65 g 0,007 g 0,0622
G03DA04 Progesterone (O) 6720 g 0,3 g 0,0461
G03DA04 Progesterone (P) 497,525 g 0,005 g 0,2047
G03DA04 Progesterone (V) 57423,9 g 0,09 g 1,3124
G03DB Pregnadien derivatives 0,7788
G03DB01 Dydrogesterone (O) 2326,8 g 0,01 g 0,4786
G03DB08 Dienogest (O) 291,872 g 2 mg 0,3002
G03F PROGESTOGENS AND ESTROGENS IN
COMBINATION 2,3092
G03FA Progestogens and estrogens, fixed combinations 1,8060
G03FA01 Norethisterone+ Estradiol (O) 533120 pieces 1 pieces 1,0965
G03FA14 Dydrogesterone+ Estradiol (O) 154784 pieces 1 pieces 0,3184
G03FA17 Drospirenone+ Estradiol (O) 190148 pieces 1 pieces 0,3911
G03FB Progestogens and estrogens, sequential preparations 0,5032
G03FB05 Norethisterone+ Estradiol (O) 171892 pieces 1 pieces 0,3536
G03FB08 Dydrogesterone+ Estradiol (O) 72744 pieces 1 pieces 0,1496
G03G GONADOTROPINS AND OTHER OVULATION
STIMULANTS 0,4647
G03GA Gonadotropins 0,2108
G03GA01 Chorionic gonadotrophin (P) 15000 U 250 U 0,0001
G03GA05 Follitropin alfa (P) 6418125 U 75 U 0,1760
G03GA07 Lutropin alfa (P) 691950 U 75 U 0,0190
G03GA08 Choriogonadotropin alfa (P) 0,9168 g 0,25 mg 0,0075
G03GA10 Follitropin delta (P) 0,005 g 12 mcg 0,0009
G03GA30 Follitropin alfa+ Lutropin alfa (P) 3542 dose 1 dose 0,0073
G03GB Ovulation stimulants, synthetic 0,2539
G03GB02 Clomifene (O) 1111 g 0,009 g 0,2539
G03H ANTIANDROGENS 0,3369
G03HA Antiandrogens, plain 0,0672
G03HA01 Cyproterone (O) 3267,5 g 0,1 g 0,0672
G03HB Antiandrogens and estrogens 0,2697
G03HB01 Cyproterone+ Estrogen (O) 98343 pieces 0,75 pieces 0,2697
17/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G03X OTHER SEX HORMONES AND MODULATORS OF
THE GENITAL SYSTEM 0,0120
G03XB Progesterone receptor modulators 0,0120
G03XB01 Mifepristone (O) 826,2 g 0,6 g 0,0028
G03XB02 Ulipristal (O) 22,4 g 5 mg 0,0092
G04 UROLOGICALS 22,4784
G04B UROLOGICALS 4,2142
G04BD Drugs for urinary frequency and incontinence 2,5239
G04BD04 Oxybutynin (O) 4618,5 g 0,015 g 0,6333
G04BD07 Tolterodine (O) 708,904 g 0,004 g 0,3645
G04BD08 Solifenacin (O) 1174,95 g 0,005 g 0,4833
G04BD09 Trospium chloride (O) 3778,65 g 0,04 g 0,1943
G04BD12 Mirabegron (O) 20625 g 50 mg 0,8485
G04BE Drugs used in erectile dysfunction 1,6776
G04BE01 Alprostadil (P) 0,0594 g 0,02 mg 0,0061
G04BE01 Alprostadil (urethral) 0,09 g 0,25 mg 0,0007
G04BE03 Sildenafil (O) 26706,2 g 0,05 g 1,0986
G04BE08 Tadalafil (O) 2460,52 g 0,01 g 0,5061
G04BE09 Vardenafil (O) 75,6 g 0,01 g 0,0155
G04BE10 Avanafil (O) 2452,8 g 0,1 g 0,0505
G04BX Other urologicals 0,0127
G04BX14 Dapoxetine (O) 185,04 g 0,03 g 0,0127
G04BX15 Pentosan polysulfate sodium (O) 9 g 0,3 g 0,0001
G04BX80 Centaurii herba+ Lovage root+ Rosemary leaf (O) 1221900 pieces
G04C DRUGS USED IN BENIGN PROSTATIC
HYPERTROPHY 18,2642
G04CA Alpha-adrenoreceptor antagonists 15,6044
G04CA01 Alfuzosin (O) 8485,8 g 7,5 mg 2,3272
G04CA02 Tamsulosin (O) 1738,3 g 0,4 mg 8,9386
G04CA04 Silodosin (O) 919,56 g 8 mg 0,2364
G04CA52 Tamsulosin+ Dutasteride (O) 1994400 pieces 1 pieces 4,1022
G04CB Testosterone-5-alpha reductase inhibitors 0,5603
G04CB01 Finasteride (O) 473,39 g 0,005 g 0,1947
G04CB02 Dutasteride (O) 88,86 g 0,5 mg 0,3655
G04CX Other drugs used in benign prostatic hypertrophy 2,0995
G04CX02 Sabalis serrulatae fructus (O) 326640 g 0,32 g 2,0995
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX
HORMONES AND INSULINS 32,7553
H01 PITUITARY AND HYPOTHALAMIC HORMONES AND
ANALOGUES 0,4774
H01A ANTERIOR PITUITARY LOBE HORMONES AND
ANALOGUES 0,1800
H01AA ACTH 0,0002
H01AA02 Tetracosactide (P) 0,0293 g 0,25 mg 0,0002
H01AB Thyrotropin 0,0004
H01AB01 Thyrotropin alfa (P) 0,1746 g 0,9 mg 0,0004
H01AC Somatropin and somatropin agonists 0,1586
H01AC01 Somatropin (P) 154200 U 2 U 0,1586
H01AX Other anterior pituitary lobe hormones and analogues 0,0208
H01AX01 Pegvisomant (P) 101,1 g 0,01 g 0,0208
H01B POSTERIOR PITUITARY LOBE HORMONES 0,1624
H01BA Vasopressin and analogues 0,1203
H01BA01 Argipressin (P) 46800 U 40 U 0,0024
H01BA02 Desmopressin (N) 0,03 g 0,025 mg 0,0025
H01BA02 Desmopressin (P) 0,0273 g 0,004 mg 0,0140
H01BA02 Desmopressin (SL) 11,835 g 0,24 mg 0,1014
H01BB Oxytocin and analogues 0,0421
H01BB01 Demoxytocin (O) 768500 U 100 U 0,0158
H01BB02 Oxytocin (P) 167600 U 15 U 0,0230
H01BB03 Carbetocin (P) 0,1608 g 0,1 mg 0,0033
18/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
H01C HYPOTHALAMIC HORMONES 0,1350
H01CA Gonadotropin-releasing hormones
H01CA01 Gonadorelin (P) 0,0038 g
H01CB Somatostatin and analogues 0,1133
H01CB02 Octreotide (P) 7,9285 g 0,7 mg 0,0233
H01CB03 Lanreotide (P) 117,48 g 3 mg 0,0805
H01CB05 Pasireotide (P) 5,5 g 1,2 mg 0,0094
H01CC Anti-gonadotropin-releasing hormones 0,0217
H01CC01 Ganirelix (P) 0,025 g 0,25 mg 0,0002
H01CC02 Cetrorelix (P) 2,615 g 0,25 mg 0,0215
H02 CORTICOSTEROIDS FOR SYSTEMIC USE 8,9653
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN 8,9616
H02AA Mineralocorticoids 0,1623
H02AA02 Fludrocortisone (O) 7,89 g 0,1 mg 0,1623
H02AB Glucocorticoids 8,7993
H02AB01 Betamethasone (P) 13,698 g 1,5 mg 0,0188
H02AB02 Dexamethasone (Infilt, P) 111 g 1,5 mg 0,1522
H02AB02 Dexamethasone (O) 1073,525 g 1,5 mg 1,4721
H02AB02 Dexamethasone (P) 822,7 g 1,5 mg 1,1281
H02AB04 Methylprednisolone (O) 6894 g 7,5 mg 1,8907
H02AB04 Methylprednisolone (P) 4152,55 g 0,02 g 0,4271
H02AB06 Prednisolone (O) 12558,8 g 0,01 g 2,5832
H02AB06 Prednisolone (P) 1607,725 g 0,01 g 0,3307
H02AB08 Triamcinolone (O) 13,6 g 7,5 mg 0,0037
H02AB08 Triamcinolone (P) 1620,6 g 7,5 mg 0,4444
H02AB09 Hydrocortisone (O) 4279,05 g 0,03 g 0,2934
H02AB09 Hydrocortisone (P) 748,4 g 0,03 g 0,0513
H02AB13 Deflazacort (O) 27 g 15 mg 0,0037
H02B CORTICOSTEROIDS FOR SYSTEMIC USE,
COMBINATIONS 0,0037
H02BX Corticosteroids for systemic use, combinations 0,0037
H02BX80 Hydrocortisone+ Lidocaine (P) 53,75 g 0,03 g 0,0037
H03 THYROID THERAPY 23,2668
H03A THYROID PREPARATIONS 22,0325
H03AA Thyroid hormones 22,0325
H03AA01 Levothyroxine sodium (O) 1606,685 g 0,15 mg 22,0314
H03AA02 Liothyronine (O) 0,032 g 0,06 mg 0,0011
H03AA03 Levothyroxine sodium+ Liothyronine (O) 300 pieces
H03AA04 Tiratricol (O) 0,378 g
H03B ANTITHYROID PREPARATIONS 1,2343
H03BA Thiouracils 0,1081
H03BA02 Propylthiouracil (O) 5255,5 g 0,1 g 0,1081
H03BB Sulfur-containing imidazole derivatives 1,1262
H03BB02 Thiamazole (O) 5475,5 g 0,01 g 1,1262
H03BC Perchlorates
H03BC01 Sodium perchlorate (O) 48 g
H04 PANCREATIC HORMONES 0,0008
H04A GLYCOGENOLYTIC HORMONES 0,0008
H04AA Glycogenolytic hormones 0,0008
H04AA01 Glucagon (P) 0,392 g 0,001 g 0,0008
H05 CALCIUM HOMEOSTASIS 0,0450
H05A PARATHYROID HORMONES AND ANALOGUES 0,0002
H05AA Parathyroid hormones and analogues 0,0002
H05AA02 Teriparatide (P) 0,0024 g 0,02 mg 0,0002
H05B ANTI-PARATHYROID AGENTS 0,0447
H05BX Other anti-parathyroid agents 0,0447
H05BX01 Cinacalcet (O) 1304,52 g 0,06 g 0,0447
J ANTIINFECTIVES FOR SYSTEMIC USE 20,6664
J01 ANTIBACTERIALS FOR SYSTEMIC USE 12,3842
J01A TETRACYCLINES 1,5468
J01AA Tetracyclines 1,5468
19/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J01AA02 Doxycycline (O) 75149 g 0,1 g 1,5457
J01AA02 Doxycycline (P) 6 g 0,1 g 0,0001
J01AA08 Minocycline (O) 9 g 0,2 g 0,0001
J01AA12 Tigecycline (P) 41 g 0,1 g 0,0008
J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS 4,8793
J01CA Penicillins with extended spectrum 1,6448
J01CA01 Ampicillin (P) 29800 g 6 g 0,0102
J01CA04 Amoxicillin (O) 1192045 g 1,5 g 1,6346
J01CA04 Amoxicillin (P) 50 g 3 g <0,0001
J01CE Beta-lactamase sensitive penicillins 0,1502
J01CE01 Benzylpenicillin (P) 32280 g 3,6 g 0,0184
J01CE02 Phenoxymethylpenicillin (O) 127347,6 g 2 g 0,1310
J01CE08 Benzathine benzylpenicillin (P) 1360,8 g 3,6 g 0,0008
J01CE80 Benzathine benzylpenicillin+ Benzylpenicillin procaine (P) 25,2 g 3,6 g <0,0001
J01CF Beta-lactamase resistant penicillins 0,0953
J01CF04 Oxacillin (P) 92650 g 2 g 0,0953
J01CR Combinations of penicillins, incl. beta-lactamase
inhibitors 2,9890
J01CR01 Ampicillin+ Sulbactam (P) 74251 g 6 g 0,0255
J01CR02 Amoxicillin+ Clavulanic acid (O) 1914772,15 g 1,5 g 2,6256
J01CR02 Amoxicillin+ Clavulanic acid (P) 347910 g 3 g 0,2385
J01CR04 Sultamicillin (O) 30582 g 1,5 g 0,0419
J01CR05 Piperacillin+ Tazobactam (P) 391160 g 14 g 0,0575
J01D OTHER BETA-LACTAM ANTIBACTERIALS 1,6711
J01DB First-generation cephalosporins 0,2261
J01DB04 Cefazolin (P) 116990 g 3 g 0,0802
J01DB05 Cefadroxil (O) 141903 g 2 g 0,1459
J01DC Second-generation cephalosporins 1,2753
J01DC01 Cefoxitin (P) 11686 g 6 g 0,0040
J01DC02 Cefuroxime (O) 262062 g 0,5 g 1,0780
J01DC02 Cefuroxime (P) 201457,5 g 3 g 0,1381
J01DC10 Cefprozil (O) 26781 g 1 g 0,0551
J01DD Third-generation cephalosporins 0,0688
J01DD01 Cefotaxime (P) 59600 g 4 g 0,0306
J01DD02 Ceftazidime (P) 14076 g 4 g 0,0072
J01DD04 Ceftriaxone (P) 27920 g 2 g 0,0287
J01DD81 Ceftazidime+ Avibactam (P) 6400 g 6 g 0,0022
J01DE Fourth-generation cephalosporins 0,0137
J01DE01 Cefepime (P) 26620 g 4 g 0,0137
J01DH Carbapenems 0,0872
J01DH02 Meropenem (P) 70183 g 3 g 0,0481
J01DH03 Ertapenem (P) 11915 g 1 g 0,0245
J01DH51 Imipenem+ Cilastatin (P) 14175 g 2 g 0,0146
J01DI Other cephalosporins and penems <0,0001
J01DI04 Cefiderocol (P) 20 g
J01DI54 Ceftolozane+ Tazobactam (P) 50 g 3 g <0,0001
J01E SULFONAMIDES AND TRIMETHOPRIM 0,4248
J01EA Trimethoprim and derivatives 0,0302
J01EA01 Trimethoprim (O) 5865 g 0,4 g 0,0302
J01EE Combinations of sulfonamides and trimethoprim, incl.
derivatives 0,3946
J01EE01 Sulfamethoxazole+ Trimethoprim (O) 840 pieces 4 pieces 0,0004
J01EE01 Sulfamethoxazole+ Trimethoprim (O) 342994 pieces 2 pieces 0,3527
J01EE01 Sulfamethoxazole+ Trimethoprim (O) 697000 ml 40 ml 0,0358
J01EE01 Sulfamethoxazole+ Trimethoprim (P) 54480 ml 20 ml 0,0056
J01F MACROLIDES, LINCOSAMIDES AND
STREPTOGRAMINS 2,4338
J01FA Macrolides 2,2306
J01FA01 Erythromycin (P) 800 g 1 g 0,0016
J01FA09 Clarithromycin (O) 384798,5 g 0,5 g 1,5829
20/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J01FA09 Clarithromycin (P) 1731 g 1 g 0,0036
J01FA10 Azithromycin (O) 93703,7 g 0,3 g 0,6424
J01FF Lincosamides 0,2032
J01FF01 Clindamycin (O) 111566,4 g 1,2 g 0,1912
J01FF01 Clindamycin (P) 10491 g 1,8 g 0,0120
J01G AMINOGLYCOSIDE ANTIBACTERIALS 0,0240
J01GB Other aminoglycosides 0,0240
J01GB01 Tobramycin (I) 119,168 g 0,112 g 0,0022
J01GB01 Tobramycin (I) 638,4 g 0,3 g 0,0044
J01GB01 Tobramycin (P) 68 g 0,24 g 0,0006
J01GB03 Gentamicin (P) 1254,925 g 0,24 g 0,0108
J01GB06 Amikacin (P) 2940 g 1 g 0,0060
J01M QUINOLONE ANTIBACTERIALS 0,7185
J01MA Fluoroquinolones 0,7185
J01MA01 Ofloxacin (O) 3356 g 0,4 g 0,0173
J01MA02 Ciprofloxacin (O) 255802,5 g 1 g 0,5261
J01MA02 Ciprofloxacin (P) 10582 g 0,8 g 0,0272
J01MA06 Norfloxacin (O) 39080 g 0,8 g 0,1005
J01MA12 Levofloxacin (O) 4620 g 0,5 g 0,0190
J01MA12 Levofloxacin (P) 323 g 0,5 g 0,0013
J01MA14 Moxifloxacin (O) 4998 g 0,4 g 0,0257
J01MA14 Moxifloxacin (P) 266,4 g 0,4 g 0,0014
J01X OTHER ANTIBACTERIALS 0,6859
J01XA Glycopeptide antibacterials 0,0262
J01XA01 Vancomycin (O) 75 g 2 g 0,0001
J01XA01 Vancomycin (P) 25295 g 2 g 0,0260
J01XA02 Teicoplanin (P) 24 g 0,4 g 0,0001
J01XB Polymyxins 0,0034
J01XB01 Colistin (I) 7600000000 U 9000000 U 0,0017
J01XB01 Colistin (P) 7220000000 U 9000000 U 0,0017
J01XD Imidazole derivatives 0,0352
J01XD01 Metronidazole (P) 25670 g 1,5 g 0,0352
J01XE Nitrofuran derivatives 0,5999
J01XE01 Nitrofurantoin (O) 58328 g 0,2 g 0,5999
J01XX Other antibacterials 0,0213
J01XX01 Fosfomycin (O) 8091 g 3 g 0,0055
J01XX05 Methenamine (O) 300 g
J01XX08 Linezolid (O) 5898 g 1,2 g 0,0101
J01XX08 Linezolid (P) 2661 g 1,2 g 0,0046
J01XX09 Daptomycin (P) 145,05 g 0,28 g 0,0011
J02 ANTIMYCOTICS FOR SYSTEMIC USE 0,3944
J02A ANTIMYCOTICS FOR SYSTEMIC USE 0,3944
J02AA Antibiotics 0,0119
J02AA01 Amphotericin (O) 285 g
J02AA01 Amphotericin (P) 202,4 g 0,035 g 0,0119
J02AB Imidazole derivatives 0,0012
J02AB02 Ketoconazole (O) 120 g 0,2 g 0,0012
J02AC Triazole and tetrazole derivatives 0,3710
J02AC01 Fluconazole (O) 16895,15 g 0,2 g 0,1738
J02AC01 Fluconazole (P) 4049,2 g 0,2 g 0,0416
J02AC02 Itraconazole (O) 11741 g 0,2 g 0,1207
J02AC03 Voriconazole (O) 1873,2 g 0,4 g 0,0096
J02AC03 Voriconazole (P) 343,4 g 0,4 g 0,0018
J02AC04 Posaconazole (O) 3206,4 g 0,3 g 0,0220
J02AC05 Isavuconazole (O) 117,6 g 0,2 g 0,0012
J02AC05 Isavuconazole (P) 29,8 g 0,2 g 0,0003
J02AX Other antimycotics for systemic use 0,0103
J02AX04 Caspofungin (P) 65,18 g 0,05 g 0,0027
J02AX05 Micafungin (P) 1 g 0,1 g <0,0001
J02AX06 Anidulafungin (P) 367,4 g 0,1 g 0,0076
J04 ANTIMYCOBACTERIALS 0,3004
21/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J04A DRUGS FOR TREATMENT OF TUBERCULOSIS 0,2844
J04AB Antibiotics 0,0412
J04AB01 Cycloserine (O) 4500 g 0,75 g 0,0123
J04AB02 Rifampicin (O) 3699,6 g 0,6 g 0,0127
J04AB02 Rifampicin (P) 207 g 0,6 g 0,0007
J04AB05 Rifapentine (O) 828 g 0,11 g 0,0155
J04AC Hydrazides 0,1882
J04AC01 Isoniazid (O) 27450 g 0,3 g 0,1882
J04AD Thiocarbamide derivatives 0,0041
J04AD01 Protionamide (O) 1500 g 0,75 g 0,0041
J04AK Other drugs for treatment of tuberculosis 0,0190
J04AK05 Bedaquiline (O) 639,2 g 86 mg 0,0153
J04AK06 Delamanid (O) 362,4 g 0,2 g 0,0037
J04AK08 Pretomanid (O) 218,4 g
J04AM Combinations of drugs for treatment of tuberculosis 0,0319
J04AM02 Rifampicin+ Isoniazid (O) 10000 pieces 4 pieces 0,0051
J04AM02 Rifampicin+ Isoniazid (O) 26000 pieces 2 pieces 0,0267
J04B DRUGS FOR TREATMENT OF LEPRA 0,0159
J04BA Drugs for treatment of lepra 0,0159
J04BA02 Dapsone (O) 387,5 g 0,05 g 0,0159
J05 ANTIVIRALS FOR SYSTEMIC USE 7,5875
J05A DIRECT ACTING ANTIVIRALS 7,5875
J05AB Nucleosides and nucleotides excl. reverse transcriptase
inhibitors 0,4901
J05AB01 Aciclovir (O) 455492,5 g 4 g 0,2342
J05AB01 Aciclovir (P) 4171,25 g 4 g 0,0021
J05AB06 Ganciclovir (P) 551 g 0,5 g 0,0023
J05AB09 Famciclovir (O) 84 g 0,75 g 0,0002
J05AB11 Valaciclovir (O) 298088 g 3 g 0,2044
J05AB12 Cidofovir (P) 16,5 g 0,025 g 0,0014
J05AB14 Valganciclovir (O) 6344 g 0,9 g 0,0145
J05AB16 Remdesivir (P) 1509,6 g 0,1 g 0,0311
J05AD Phosphonic acid derivatives 0,0009
J05AD01 Foscarnet sodium (P) 2694 g 6,5 g 0,0009
J05AE Protease inhibitors 0,5651
J05AE03 Ritonavir (O) 35733 g 1,2 g 0,0612
J05AE10 Darunavir (O) 293928 g 1,2 g 0,5038
J05AE30 Nirmatrelvir+ Ritonavir (O) 1080 pieces
J05AF Nucleoside and nucleotide reverse transcriptase
inhibitors 0,1463
J05AF01 Zidovudine (O) 430 g 0,6 g 0,0015
J05AF01 Zidovudine (P) 6 g 0,6 g <0,0001
J05AF05 Lamivudine (O) 1542 g 0,3 g 0,0106
J05AF06 Abacavir (O) 1963,2 g 0,6 g 0,0067
J05AF07 Tenofovir disoproxil (O) 404,25 g 0,245 g 0,0034
J05AF10 Entecavir (O) 28,455 g 0,5 mg 0,1171
J05AF13 Tenofovir alafenamide (O) 86,25 g 25 mg 0,0071
J05AG Non-nucleoside reverse transcriptase inhibitors 0,7490
J05AG05 Rilpivirine (O) 9104,25 g 25 mg 0,7490
J05AH Neuraminidase inhibitors 0,2602
J05AH01 Zanamivir (P) 12 g 1,2 g <0,0001
J05AH02 Oseltamivir (O) 18970,5 g 0,15 g 0,2601
J05AJ Integrase inhibitors 1,6100
J05AJ01 Raltegravir (O) 586368 g 0,8 g 1,5076
J05AJ03 Dolutegravir (O) 2489,85 g 50 mg 0,1024
J05AP Antivirals for treatment of HCV infections 0,1333
J05AP01 Ribavirin (O) 16,8 g 1 g <0,0001
J05AP54 Elbasvir+ Grazoprevir (O) 10388 pieces 1 pieces 0,0214
J05AP55 Sofosbuvir+ Velpatasvir (O) 6300 pieces 1 pieces 0,0130
J05AP57 Glecaprevir+ Pibrentasvir (O) 144256 pieces 3 pieces 0,0989
22/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J05AR Antivirals for treatment of HIV infections, combinations 3,6326
J05AR02 Lamivudine+ Abacavir (O) 181680 pieces 1 pieces 0,3737
J05AR03 Tenofovir disoproxil+ Emtricitabine (O) 1120410 pieces 1 pieces 2,3045
J05AR06 Emtricitabine+ Tenofovir disoproxil+ Efavirenz (O) 152850 pieces 1 pieces 0,3144
J05AR10 Lopinavir+ Ritonavir (O) 15840 g 0,8 g 0,0407
J05AR13 Lamivudine+ Abacavir+ Dolutegravir (O) 128040 pieces 1 pieces 0,2634
J05AR18 Emtricitabine+ Tenofovir alafenamide+ Elvitegravir+
Cobicistat (O) 480 pieces 1 pieces 0,0010
J05AR25 Lamivudine+ Dolutegravir (O) 162840 pieces 1 pieces 0,3349
J05AX Other antivirals
J05AX10 Maribavir (O) 48 g
J06 IMMUNE SERA AND IMMUNOGLOBULINS
J06A IMMUNE SERA
J06AA Immune sera
J06AA01 Diphtheria antitoxin (P) 20 pieces
J06AA03 Snake venom antiserum (P) 76 pieces
J06B IMMUNOGLOBULINS
J06BA Immunoglobulins, normal human
J06BA01 Immunoglobulins, normal human, for extravascular a (P) 12326,1 g
J06BA02 Immunoglobulins, normal human, for intravascular a (P) 125407,5 g
J06BB Specific immunoglobulins
J06BB01 Human Anti-D Immunoglobulin (P) 1791875 U
J06BB02 Tetanus immunoglobulins (P) 6000 U
J06BB03 Varicella-zoster immune globulin (P) 1250 U
J06BB04 Hepatitis B immunoglobulins (P) 1000 U
J06BB05 Rabies immunoglobulin (P) 1500 U
J06BB09 Cytomegalovirus immunoglobulin (P) 120000 U
J06BD Antiviral monoclonal antibodies
J06BD01 Palivizumab (P) 32,3 g
J06BD03 Tixagevimab+ Cilgavimab (P) 1296 ml
J06BD06 Regdanvimab (P) 76,8 g
J07 VACCINES
J07A BACTERIAL VACCINES
J07AG Hemophilus influenzae B vaccines
J07AG01 Haemophilus influenzae B, purified antigen conjugated
(P) 273 dose
J07AH Meningococcal vaccines
J07AH08 Meningococcus, tetravalent purified polysaccharides
antigen conjugated (P) 203 dose
J07AH09 Meningococcus B, multicomponent vaccine (P) 118 dose
J07AL Pneumococcal vaccines
J07AL01 Pneumococcus, purified polysaccharides antigen (P) 500 dose
J07AL02 Pneumococcus, purified polysaccharides antigen
conjugated (P) 2658 dose
J07AL52 Pneumococcus, purified polysaccharides antigen+
Haemophilus influenzae, conjugated (P) 226 dose
J07AM Tetanus vaccines
J07AM51 Tetanus toxoid+ Diphtheria toxoid (P) 81976 dose
J07AN Tuberculosis vaccines
J07AN01 Tuberculosis, live attenuated (P) 1771 dose
J07AP Typhoid vaccines
J07AP03 Typhoid, purified polysaccharide antigen (P) 850 dose
J07AX Other bacterial vaccines
J07AX80 Diphtheria-tetanus-pertussis (P) 18080 dose
J07B VIRAL VACCINES
J07BA Encephalitis vaccines
J07BA01 Encephalitis, tick borne, inactivated, whole virus (P) 72595 dose
23/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J07BB Influenza vaccines
J07BB02 Influenza, inactivated, split virus or surface antigen (P) 191263 dose
J07BB03 Influenza vaccine (live attenuated, nasal) (N) 1890 dose
J07BC Hepatitis vaccines
J07BC01 Hepatitis B, purified antigen (P) 4851 dose
J07BC02 Hepatitis A, inactivated, whole virus (P) 2627 dose
J07BC80 Hepatitis A, inactivated, whole virus+ Hepatitis B, purified
antigen (P) 1294 dose
J07BD Measles vaccines
J07BD52 Measles virus (live, attenuated)+ Rubella virus (live,
attenuated)+ Mumps virus (live, attenuated) (P) 35869 dose
J07BF Poliomyelitis vaccines
J07BF03 Poliomyelitis, trivalent, inactivated, whole virus (P) 712 dose
J07BG Rabies vaccines
J07BG01 Rabies, inactivated, whole virus (P) 1706 dose
J07BH Rota virus diarrhea vaccines
J07BH02 Rota virus, pentavalent, live, reassorted (O) 39281 dose
J07BK Varicella zoster vaccines
J07BK01 Varicella, live attenuated (P) 2283 dose
J07BK02 Zoster, live attenuated (P) 88 dose
J07BK03 Zoster, purified antigen (P) 8 dose
J07BL Yellow fever vaccines
J07BL01 Yellow fever virus live, attenuated (P) 1249 dose
J07BM Papillomavirus vaccines
J07BM02 Human papillomavirus vaccine (types 16, 18)
recombinant, adjuvanted, adsorbed (P) 3 dose
J07BM03 Human papillomavirus vaccine (types 6, 11, 16, 18, 31,
33, 45, 52, 58) (P) 13833 dose
J07BN Covid-19 vaccines
J07BN01 Covid-19, RNA-based vaccine (P) 78980 dose
J07BN01 Covid-19, RNA-based vaccine (P) 434224,269 dose
J07BN02 Covid-19, viral vector, non-replicating (P) 17600 dose
J07BN04 Covid-19, protein subunit (P) 29070 dose
J07BX Other viral vaccines
J07BX01 Smallpox vaccine (P) 600 dose
J07C BACTERIAL AND VIRAL VACCINES, COMBINED
J07CA Bacterial and viral vaccines, combined
J07CA02
Diphtheria toxoid+ Pertussis, purified antigen+ Tetanus
toxoid+ Poliomyelitis, trivalent, inactivated, whole virus
(P)
13355 dose
J07CA06
Diphtheria toxoid+ Tetanus toxoid+ Pertussis, purified
antigen+ Poliomyelitis, trivalent, inactivated, whole virus+
Haemophilus influenzae B, purified antigen conjugated
(P)
642 dose
J07CA09
Diphtheria toxoid+ Poliomyelitis, trivalent, inactivated,
whole virus+ Pertussis, purified antigen+ Haemophilus
influenzae B, purified antigen conjugated+ Hepatitis B,
purified antigen+ Tetanus toxoid (P)
60158 dose
L ANTINEOPLASTIC AND IMMUNOMODULATING
AGENTS 13,9703
L01 ANTINEOPLASTIC AGENTS 0,5300
L01A ALKYLATING AGENTS
L01AA Nitrogen mustard analogues
L01AA01 Cyclophosphamide (O) 390 g
L01AA01 Cyclophosphamide (P) 3315 g
L01AA02 Chlorambucil (O) 11,55 g
L01AA03 Melphalan (O) 2,45 g
L01AA03 Melphalan (P) 15,5 g
24/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01AA06 Ifosfamide (P) 1984,5 g
L01AA07 Trofosfamide (O) 10 g
L01AA09 Bendamustine (P) 97,5 g
L01AB Alkyl sulfonates
L01AB01 Busulfan (O) 5,6 g
L01AB01 Busulfan (P) 1,44 g
L01AB02 Treosulfan (P) 600 g
L01AC Ethylene imines
L01AC01 Thiotepa (P) 3,745 g
L01AD Nitrosoureas
L01AD01 Carmustine (P) 9,2 g
L01AD02 Lomustine (O) 22 g
L01AD04 Streptozocin (P) 1 g
L01AX Other alkylating agents
L01AX03 Temozolomide (O) 785,3 g
L01AX04 Dacarbazine (P) 206 g
L01B ANTIMETABOLITES
L01BA Folic acid analogues
L01BA01 Methotrexate (P) 639,7 g
L01BA04 Pemetrexed (P) 464 g
L01BB Purine analogues
L01BB02 Mercaptopurine (O) 292,5 g
L01BB03 Tioguanine (O) 6 g
L01BB04 Cladribine (P) 0,43 g
L01BB05 Fludarabine (P) 16,5 g
L01BB06 Clofarabine (P) 0,5 g
L01BB07 Nelarabine (P) 21 g
L01BC Pyrimidine analogues
L01BC01 Cytarabine (P) 1609 g
L01BC02 Fluorouracil (C) 60 g
L01BC02 Fluorouracil (P) 13723 g
L01BC05 Gemcitabine (P) 6133,88 g
L01BC06 Capecitabine (O) 270435 g
L01BC07 Azacitidine (P) 438,1 g
L01BC82 Fluorouracil+ Salicylic acid (C) 300 ml
L01BC83 Trifluridine+ Tipiracil (O) 19240 pieces
L01C PLANT ALKALOIDS AND OTHER NATURAL
PRODUCTS
L01CA Vinca alkaloids and analogues
L01CA01 Vinblastine (P) 1,94 g
L01CA02 Vincristine (P) 2,021 g
L01CA04 Vinorelbine (O) 0,64 g
L01CA04 Vinorelbine (P) 18,45 g
L01CB Podophyllotoxin derivatives
L01CB01 Etoposide (O) 233 g
L01CB01 Etoposide (P) 466 g
L01CD Taxanes
L01CD01 Paclitaxel (P) 997,4 g
L01CD02 Docetaxel (P) 457,28 g
L01CD04 Cabazitaxel (P) 2,64 g
L01CE Topoisomerase 1 (TOP1) inhibitors
L01CE01 Topotecan (P) 2,02 g
L01CE02 Irinotecan (P) 700 g
L01CX Other plant alkaloids and natural products
L01CX01 Trabectedin (P) 0,0125 g
L01D CYTOTOXIC ANTIBIOTICS AND RELATED
SUBSTANCES
L01DA Actinomycines
L01DA01 Dactinomycin (P) 0,0665 g
L01DB Anthracyclines and related substances
L01DB01 Doxorubicin (P) 117,7 g
25/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01DB02 Daunorubicin (P) 14,38 g
L01DB03 Epirubicin (P) 188,5 g
L01DB06 Idarubicin (O) 0,08 g
L01DB06 Idarubicin (P) 0,35 g
L01DB07 Mitoxantrone (P) 1,44 g
L01DB11 Pixantrone (P) 1,276 g
L01DC Other cytotoxic antibiotics
L01DC01 Bleomycin (P) 6000000 U
L01DC03 Mitomycin (P) 3,54 g
L01E PROTEIN KINASE INHIBITORS 0,5300
L01EA BCR-ABL tyrosine kinase inhibitors 0,1336
L01EA01 Imatinib (O) 15972 g 0,4 g 0,0821
L01EA02 Dasatinib (O) 612 g 0,1 g 0,0126
L01EA03 Nilotinib (O) 10080 g 0,6 g 0,0346
L01EA04 Bosutinib (O) 453,6 g 0,4 g 0,0023
L01EA05 Ponatinib (O) 43,2 g 45 mg 0,0020
L01EB Epidermal growth factor receptor (EGFR) tyrosine kinase
inhibitors 0,0227
L01EB01 Gefitinib (O) 1387,5 g 0,25 g 0,0114
L01EB02 Erlotinib (O) 24 g 0,15 g 0,0003
L01EB03 Afatinib (O) 89,04 g 40 mg 0,0046
L01EB04 Osimertinib (O) 249,6 g 80 mg 0,0064
L01EB10 Mobocertinib (O) 14,4 g
L01EC B-Raf serine-threonine kinase (BRAF) inhibitors 0,0186
L01EC02 Dabrafenib (O) 2709 g 0,3 g 0,0186
L01ED Anaplastic lymphoma kinase (ALK) inhibitors 0,0120
L01ED01 Crizotinib (O) 30 g 0,5 g 0,0001
L01ED02 Ceritinib (O) 247,5 g 0,45 g 0,0011
L01ED03 Alectinib (O) 2083,2 g 1,2 g 0,0036
L01ED04 Brigatinib (O) 627,48 g 0,18 g 0,0072
L01EE Mitogen-activated protein kinase (MEK) inhibitors 0,0200
L01EE01 Trametinib (O) 19,425 g 2 mg 0,0200
L01EE03 Binimetinib (O) 2,52 g 90 mg 0,0001
L01EE04 selumetinib (O) 19,2 g
L01EF Cyclin-dependent kinase (CDK) inhibitors 0,1021
L01EF01 Palbociclib (O) 3719,625 g 94 mg 0,0814
L01EF02 Ribociclib (O) 4536 g 0,45 g 0,0207
L01EG Mammalian target of rapamycin (mTOR) kinase
inhibitors 0,0097
L01EG01 Temsirolimus (P) 2,28 g 3,57 mg 0,0013
L01EG02 Everolimus (O) 40,8 g 10 mg 0,0084
L01EJ Janus-associated kinase (JAK) inhibitors 0,0201
L01EJ01 Ruxolitinib (C) 0,9 g
L01EJ01 Ruxolitinib (O) 292,6 g 30 mg 0,0201
L01EK Vascular endothelial growth factor receptor (VEGFR)
tyrosine kinase inhibitors 0,0017
L01EK01 Axitinib (O) 8,288 g 10 mg 0,0017
L01EL Bruton's tyrosine kinase (BTK) inhibitors 0,0548
L01EL01 Ibrutinib (O) 10122 g 0,42 g 0,0496
L01EL02 Acalabrutinib (O) 510 g 0,2 g 0,0052
L01EX Other protein kinase inhibitors 0,1346
L01EX01 Sunitinib (O) 457,45 g 33 mg 0,0285
L01EX02 Sorafenib (O) 2710,4 g 0,8 g 0,0070
L01EX03 Pazopanib (O) 11658 g 0,8 g 0,0300
L01EX04 Vandetanib (O) 27 g 0,3 g 0,0002
L01EX05 regorafenib (O) 164,64 g 0,12 g 0,0028
L01EX07 Cabozantinib (O) 499,24 g 60 mg 0,0171
L01EX08 Lenvatinib (O) 82,74 g 18 mg 0,0095
L01EX09 Nintedanib (O) 6825 g 0,38 g 0,0369
L01EX10 Midostaurin (O) 114,8 g 0,1 g 0,0024
L01EX14 Entrectinib (O) 90 g 0,6 g 0,0003
26/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01F MONOCLONAL ANTIBODIES AND ANTIBODY DRUG
CONJUGATES
L01FA CD20 (Clusters of Differentiation 20) inhibitors
L01FA01 Rituximab (P) 1830,28 g
L01FA03 Obinutuzumab (P) 136 g
L01FB CD22 (Clusters of Differentiation 22) inhibitors
L01FB01 Inotuzumab ozogamicin (P) 0,012 g
L01FC CD38 (Clusters of Differentiation 38) inhibitors
L01FC01 Daratumumab (P) 1283,4 g
L01FD HER2 (Human Epidermal Growth Factor Receptor 2)
inhibitors
L01FD01 Trastuzumab (P) 1393,95 g
L01FD02 Pertuzumab (P) 90,3 g
L01FD03 Trastuzumab emtansine (P) 155,32 g
L01FD04 Trastuzumab deruxtecan (P) 17,5 g
L01FE EGFR (Epidermal Growth Factor Receptor) inhibitors
L01FE01 Cetuximab (P) 9,8 g
L01FE02 Panitumumab (P) 72,1 g
L01FF PD-1/PDL-1 (Programmed cell death protein 1/death
ligand 1) inhibitors
L01FF01 Nivolumab (P) 408,96 g
L01FF02 Pembrolizumab (P) 441 g
L01FF03 Durvalumab (P) 381 g
L01FF05 Atezolizumab (P) 847,2 g
L01FG VEGF/VEGFR (Vascular Endothelial Growth Factor)
inhibitors
L01FG01 Bevacizumab (P) 1530 g
L01FG02 Ramucirumab (P) 4,3 g
L01FX Other monoclonal antibodies and antibody drug
conjugates
L01FX02 Gemtuzumab ozogamicin (P) 0,005 g
L01FX04 Ipilimumab (P) 1,75 g
L01FX05 Brentuximab vedotin (P) 13,15 g
L01FX06 Dinutuximab beta (P) 0,5063 g
L01FX07 Blinatumomab (P) 0,0015 g
L01FX09 Mogamulizumab (P) 0,32 g
L01FX20 Tremelimumab (P) 0,3 g
L01X OTHER ANTINEOPLASTIC AGENTS
L01XA Platinum compounds
L01XA01 Cisplatin (P) 189,4 g
L01XA02 Carboplatin (P) 2028 g
L01XA03 Oxaliplatin (P) 883,8 g
L01XB Methylhydrazines
L01XB01 Procarbazine (O) 145 g
L01XD Sensitizers used in photodynamic/radiation therapy
L01XD04 Aminolevulinic acid (O) 39 g
L01XF Retinoids for cancer treatment
L01XF01 Tretinoin (O) 101 g
L01XG Proteasome inhibitors
L01XG01 Bortezomib (P) 9,324 g
L01XG02 Carfilzomib (P) 22,51 g
L01XG03 Ixazomib (O) 0,6 g
L01XJ Hedgehog pathway inhibitors
L01XJ01 Vismodegib (O) 25,2 g
L01XK Poly (ADP-ribose) polymerase (PARP) inhibitors
L01XK01 Olaparib (O) 9116,8 g
L01XX Other antineoplastic agents
L01XX01 Amsacrine (P) 1,35 g
L01XX02 Asparaginase (P) 1950000 U
L01XX05 Hydroxycarbamide (O) 265300 g
27/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01XX11 Estramustine (O) 44,8 g
L01XX23 Mitotane (O) 900 g
L01XX24 Pegaspargase (P) 168750 U
L01XX27 Arsenic trioxide (P) 9,86 g
L01XX35 Anagrelide (O) 1,15 g
L01XX41 Eribulin (P) 0,3458 g
L01XX52 Venetoclax (O) 5611,34 g
L01XX73 Sotorasib (O) 172,8 g
L01XX75 Tebentafusp (P) 0,0054 g
L01XY Combinations of antineoplastic agents
L01XY02 Pertuzumab+ Trastuzumab (P) 7330 ml
L02 ENDOCRINE THERAPY 5,0127
L02A HORMONES AND RELATED AGENTS 0,9032
L02AB Progestogens 0,0098
L02AB02 Medroxyprogesterone (O) 4770 g 1 g 0,0098
L02AE Gonadotropin releasing hormone analogues 0,8934
L02AE03 Goserelin (P) 10,8216 g 0,129 mg 0,1725
L02AE04 Triptorelin (P) 0,3738 g 0,1 mg 0,0077
L02AE04 Triptorelin (P) 46,4625 g 0,134 mg 0,7132
L02B HORMONE ANTAGONISTS AND RELATED AGENTS 4,1095
L02BA Anti-estrogens 0,8139
L02BA01 Tamoxifen (O) 6365,4 g 0,02 g 0,6546
L02BA03 Fulvestrant (P) 642,5 g 8,3 mg 0,1592
L02BB Anti-androgens 1,0476
L02BB03 Bicalutamide (O) 23994,6 g 0,05 g 0,9871
L02BB04 enzalutamide
(O) 4341,12 g 0,16 g 0,0558
L02BB05 Apalutamide (O) 144 g 0,24 g 0,0012
L02BB06 Darolutamide (O) 2049,6 g 1,2 g 0,0035
L02BG Aromatase inhibitors 2,1515
L02BG03 Anastrozole (O) 361,92 g 1 mg 0,7444
L02BG04 Letrozole (O) 1558,2 g 2,5 mg 1,2820
L02BG06 Exemestane (O) 1521 g 0,025 g 0,1251
L02BX Other hormone antagonists and related agents 0,0964
L02BX03 Abiraterone (O) 46890 g 1 g 0,0964
L03 IMMUNOSTIMULANTS 0,4213
L03A IMMUNOSTIMULANTS 0,4213
L03AA Colony stimulating factors 0,0884
L03AA02 Filgrastim (P) 10,0323 g 0,35 mg 0,0590
L03AA13 Pegfilgrastim (P) 4,29 g 0,3 mg 0,0294
L03AB Interferons 0,2393
L03AB07 Interferon beta-1a (P) 0,3483 g 0,0043 mg 0,1666
L03AB08 Interferon beta-1b (P) 62760000000 U 4000000 U 0,0323
L03AB11 Peginterferon alfa-2a (P) 0,0567 g 0,026 mg 0,0045
L03AB13 Peginterferon beta-1a (P) 0,1556 g 8,9 mcg 0,0360
L03AX Other immunostimulants 0,0936
L03AX03 BCG bacteria (P) 4,1375 g 1,8 mg 0,0047
L03AX13 Glatiramer acetate (P) 863,52 g 0,02 g 0,0888
L03AX16 Plerixafor (P) 0,432 g 16,8 mg 0,0001
L04 IMMUNOSUPPRESSANTS 8,0064
L04A IMMUNOSUPPRESSANTS 8,0064
L04AA Selective immunosuppressants 1,2610
L04AA03 Anti-T lymphocyte immunoglobulin for human use, horse
(P) 7,5 g
L04AA04 Anti-T lymphocyte immunoglobulin for human use, rabbit
(P) 12,375 g 0,1 g 0,0003
L04AA06 Mycophenolic acid (O) 307761 g 2 g 0,3165
L04AA06 Mycophenolic acid (P) 234 g 2 g 0,0002
L04AA10 Sirolimus (O) 26,58 g 0,003 g 0,0182
L04AA13 Leflunomide (O) 4878,9 g 0,02 g 0,5018
28/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L04AA18 Everolimus (O) 0,36 g 1,5 mg 0,0005
L04AA23 Natalizumab (P) 56,1 g 0,01 g 0,0115
L04AA24 Abatacept (P) 238 g 0,027 g 0,0181
L04AA25 Eculizumab (P) 102,3 g 0,064 g 0,0033
L04AA26 Belimumab (P) 4,8 g 25 mg 0,0004
L04AA27 Fingolimod (O) 3,416 g 0,5 mg 0,0141
L04AA29 Tofacitinib
(O) 143,528 g 10 mg 0,0295
L04AA31 Teriflunomide (O) 747,936 g 14 mg 0,1099
L04AA33 Vedolizumab (P) 93,3 g 5,4 mg 0,0355
L04AA34 Alemtuzumab (P) 0,504 g 0,13 mg 0,0080
L04AA36 Ocrelizumab (P) 130,8 g 3,29 mg 0,0818
L04AA37 Baricitinib
(O) 3,92 g 3 mg 0,0027
L04AA40 Cladribine (O) 2,5 g 0,34 mg 0,0151
L04AA42 Siponimod (O) 40,462 g
L04AA43 ravulizumab (P) 5,2 g 58,9 mg 0,0002
L04AA44 Upadacitinib (O) 447,3 g 15 mg 0,0613
L04AA47 Inebilizumab (P) 1,2 g
L04AA50 Ponesimod (O) 32,274 g 20 mg 0,0033
L04AA52 Ofatumumab (P) 9,38 g 0,67 mg 0,0288
L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors 1,7520
L04AB01 Etanercept (P) 1139,1 g 0,007 g 0,3347
L04AB02 Infliximab (P) 1161,8 g 3,75 mg 0,6372
L04AB04 Adalimumab (P) 965,64 g 2,9 mg 0,6849
L04AB05 Certolizumab pegol (P) 28,8 g 14 mg 0,0042
L04AB06 Golimumab (P) 73,35 g 1,66 mg 0,0909
L04AC Interleukin inhibitors 0,6313
L04AC02 Basiliximab (P) 1,04 g 0,04 g 0,0001
L04AC03 Anakinra (P) 124,5195 g 0,1 g 0,0026
L04AC05 Ustekinumab (P) 85,62 g 0,54 mg 0,3261
L04AC07 Tocilizumab (P) 902,312 g 0,02 g 0,0928
L04AC10 Secukinumab (P) 511,65 g 10 mg 0,1052
L04AC13 Ixekizumab (P) 30,4 g 2,9 mg 0,0216
L04AC14 Sarilumab (P) 136,4 g 14,3 mg 0,0196
L04AC16 Guselkumab (P) 21,2 g 1,79 mg 0,0244
L04AC18 Risankizumab (P) 31,65 g 1,67 mg 0,0390
L04AD Calcineurin inhibitors 0,5096
L04AD01 Ciclosporin (O) 29483,75 g 0,25 g 0,2426
L04AD01 Ciclosporin (P) 57,5 g 0,25 g 0,0005
L04AD02 Tacrolimus (O) 647,6 g 5 mg 0,2664
L04AD02 Tacrolimus (P) 0,3 g 5 mg 0,0001
L04AX Other immunosuppressants 3,8525
L04AX01 Azathioprine (O) 32905 g 0,15 g 0,4512
L04AX02 Thalidomide (O) 177,8 g 0,1 g 0,0037
L04AX03 Methotrexate (O) 3572,95 g 2,5 mg 2,9396
L04AX03 Methotrexate (P) 146,075 g 2,5 mg 0,1202
L04AX04 Lenalidomide (O) 513,66 g 0,01 g 0,1057
L04AX05 Pirfenidone (O) 18570,384 g 2,4 g 0,0159
L04AX06 Pomalidomide
(O) 12,747 g 3 mg 0,0087
L04AX07 Dimethyl fumarate (O) 40375,44 g 0,48 g 0,1730
L04AX09 Diroximel fumarate (O) 15523,2 g 0,924 g 0,0346
M MUSCULO-SKELETAL SYSTEM 91,7225
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC
PRODUCTS 73,1429
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC
PRODUCTS, NON-STEROIDS 73,1321
M01AB Acetic acid derivatives and related substances 8,8031
M01AB01 Indometacin (O) 1553,275 g 0,1 g 0,0319
M01AB05 Diclofenac (O) 286682,25 g 0,1 g 5,8966
29/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
M01AB05 Diclofenac (P) 7467,375 g 0,1 g 0,1536
M01AB05 Diclofenac (R) 11719,375 g 0,1 g 0,2411
M01AB15 Ketorolac (P) 0,3 g 30 mg <0,0001
M01AB16 Aceclofenac (O) 44684 g 0,2 g 0,4595
M01AB82 Diclofenac+ Omeprazole (O) 98221,5 g 0,1 g 2,0203
M01AC Oxicams 3,5788
M01AC01 Piroxicam (O) 989,2 g 0,02 g 0,1017
M01AC05 Lornoxicam (O) 2015,36 g 0,012 g 0,3454
M01AC06 Meloxicam (O) 22681,875 g 0,015 g 3,1102
M01AC06 Meloxicam (P) 156 g 0,015 g 0,0214
M01AE Propionic acid derivatives 43,5330
M01AE01 Ibuprofen (O) 16187635,2 g 1,2 g 27,7463
M01AE01 Ibuprofen (P) 10706 g 1,2 g 0,0184
M01AE02 Naproxen (O) 776690,75 g 0,5 g 3,1951
M01AE03 Ketoprofen (O) 149395,5 g 0,15 g 2,0486
M01AE03 Ketoprofen (P) 11820 g 0,15 g 0,1621
M01AE17 Dexketoprofen (O) 90957 g 0,075 g 2,4945
M01AE17 Dexketoprofen (P) 3687,25 g 0,075 g 0,1011
M01AE52 Naproxen+ Esomeprazole (O) 1887150 g 0,5 g 7,7632
M01AE82 Ibuprofen+ Phenylephrine (O) 2275,2 g 1,2 g 0,0039
M01AG Fenamates 0,0037
M01AG02 Tolfenamic acid (O) 540 g 0,3 g 0,0037
M01AH Coxibs 10,1303
M01AH01 Celecoxib (O) 86967 g 0,2 g 0,8944
M01AH05 Etoricoxib (O) 269417,61 g 60 mg 9,2359
M01AX Other antiinflammatory and antirheumatic agents, non-
steroids 7,0833
M01AX01 Nabumetone (O) 141280 g 1 g 0,2906
M01AX05 Glucosamine (O) 4953734,04 g 1,5 g 6,7927
M01C SPECIFIC ANTIRHEUMATIC AGENTS 0,0108
M01CC Penicillamine and similar agents 0,0108
M01CC01 Penicillamine (O) 2617,5 g 0,5 g 0,0108
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR
PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR
PAIN
M02AA Antiinflammatory preparations, non-steroids for topical
use
M02AA10 Ketoprofen (C) 1202850 g
M02AA12 Naproxen (C) 1081190 g
M02AA13 Ibuprofen (C) 31324 pieces
M02AA13 Ibuprofen (C) 890800 g
M02AA15 Diclofenac (C) 461939 pieces
M02AA15 Diclofenac (C) 32275750 g
M02AA81 Ibuprofen+ Levomenthol (C) 1953800 g
M02AC Preparations with salicylic acid derivatives
M02AC80 Methyl salicylate+ Levomenthol+ Eucalyptus oil+
Turpentine oil (C) 127635 g
M02AX Other topical products for joint and muscular pain
M02AX80 Nicoboxil+ Nonivamide (C) 211100 g
M02AX90 Camphor+ Salicylic acid+ Turpentine oil+ Viperae beri
venenum (C) 996575 g
M02AX92 Benzyl nicotinate+ Nonivamide+ Camphor+ Turpentine
oil+ Dimethyl sulfoxide (C) 752880 g
M03 MUSCLE RELAXANTS 0,9974
M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING
AGENTS
M03AB Choline derivatives
M03AB01 Suxamethonium chloride (P) 3050 g
M03AC Other quaternary ammonium compounds
M03AC03 Vecuronium bromide (P) 0,1 g
30/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
M03AC04 Atracurium besilate (P) 2013,625 g
M03AC06 Pipecuronium bromide (P) 8,7 g
M03AC09 Rocuronium bromide (P) 1244 g
M03AX Other muscle relaxants, peripherally acting agents
M03AX01 Botulinum toxin (P) 2404950 U
M03B MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS 0,9974
M03BX Other centrally acting agents 0,9974
M03BX01 Baclofen (O) 4550,5 g 0,05 g 0,1872
M03BX01 Baclofen (P) 2,0528 g 0,55 mg 0,0077
M03BX02 Tizanidine (O) 4682,04 g 0,012 g 0,8025
M04 ANTIGOUT PREPARATIONS 12,5230
M04A ANTIGOUT PREPARATIONS 12,5230
M04AA Preparations inhibiting uric acid production 12,5032
M04AA01 Allopurinol (O) 1606220 g 0,4 g 8,2594
M04AA03 Febuxostat (O) 165060 g 0,08 g 4,2438
M04AB Preparations increasing uric acid excretion 0,0023
M04AB01 Probenecid (O) 100 g 1 g 0,0002
M04AB03 Benzbromarone (O) 100 g 0,1 g 0,0021
M04AC Preparations with no effect on uric acid metabolism 0,0176
M04AC01 Colchicine (O) 8,555 g 1 mg 0,0176
M05 DRUGS FOR TREATMENT OF BONE DISEASES 5,0512
M05B DRUGS AFFECTING BONE STRUCTURE AND
MINERALIZATION 5,0512
M05BA Bisphosphonates 0,7600
M05BA03 Pamidronic acid (P) 3 g 0,06 g 0,0001
M05BA04 Alendronic acid (O) 259 g 0,01 g 0,0533
M05BA06 Ibandronic acid (O) 1402,2 g 0,005 g 0,5768
M05BA07 Risedronic acid (O) 294,42 g 0,005 g 0,1211
M05BA08 Zoledronic acid (P) 16,978 g 0,004 g 0,0087
M05BB Bisphosphonates, combinations 2,6040
M05BB03 Alendronic acid+ Colecalciferol (O) 12659,92 g 10 mg 2,6040
M05BX Other drugs affecting bone structure and mineralization 1,6872
M05BX04 Denosumab (P) 270,343 g 0,33 mg 1,6850
M05BX05 Burosumab (P) 2,7 g 2,5 mg 0,0022
M05BX07 Vosoritide (P) 0,3472 g
M09 OTHER DRUGS FOR DISORDERS OF THE MUSCULO-
SKELETAL SYSTEM 0,0079
M09A OTHER DRUGS FOR DISORDERS OF THE MUSCULO-
SKELETAL SYSTEM 0,0079
M09AX Other drugs for disorders of the musculo-skeletal system 0,0079
M09AX10 Risdiplam (O) 19,32 g 5 mg 0,0079
N NERVOUS SYSTEM 160,8567
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AB Halogenated hydrocarbons
N01AB06 Isoflurane (I) 5000 ml
N01AB07 Desflurane (I) 84960 ml
N01AB08 Sevoflurane (I) 823250 ml
N01AF Barbiturates, plain
N01AF03 Thiopental (P) 2330 g
N01AH Opioid anesthetics
N01AH01 Fentanyl (I) 0,212 g
N01AH01 Fentanyl (P) 37,561 g
N01AH06 Remifentanil (P) 23,76 g
N01AX Other general anesthetics
N01AX03 Ketamine (P) 1317 g
N01AX07 Etomidate (P) 39,9 g
N01AX10 Propofol (P) 87958,5 g
31/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N01AX13 Nitrous oxide (I) 11696000 ml
N01AX14 Esketamine (P) 442 g
N01B ANESTHETICS, LOCAL
N01BB Amides
N01BB01 Bupivacaine (Infilt, P) 3639,75 g
N01BB01 Bupivacaine (P) 256,1 g
N01BB02 Lidocaine (C) 2730 pieces
N01BB02 Lidocaine (C) 5100 ml
N01BB02 Lidocaine (NA) 5400 ml
N01BB02 Lidocaine (NA) 87026 g
N01BB02 Lidocaine (O) 101760 g
N01BB02 Lidocaine (P) 26036,3 g
N01BB03 Mepivacaine (dental) 1379,55 g
N01BB08 Articaine (P) 2,4 g
N01BB09 Ropivacaine (P) 897,3 g
N01BB80 Articaine+ Epinephrine (dental) 933980 ml
N01BB80 Articaine+ Epinephrine (O) 603360 ml
N01BB81 Bupivacaine+ Epinephrine (P) 260800 ml
N01BB82 Lidocaine+ Epinephrine (dental) 1100 ml
N01BB82 Lidocaine+ Epinephrine (dental, P) 86000 ml
N01BB83 Lidocaine+ Prilocaine (C) 97920 g
N01BB86 Lidocaine+ Chlorhexidine (urethral) 1422562,5 g
N01BC Esters of benzoic acid
N01BC01 Cocaine (NA) 485 g
N01BX Other local anesthetics
N01BX04 Capsaicin (C) 154220 g
N02 ANALGESICS 39,1300
N02A OPIOIDS 10,5817
N02AA Natural opium alkaloids 0,9972
N02AA01 Morphine (O) 4234,5 g 0,1 g 0,0871
N02AA01 Morphine (P) 552,1 g 0,03 g 0,0379
N02AA05 Oxycodone (O) 26376,15 g 0,075 g 0,7234
N02AA05 Oxycodone (P) 425,8 g 0,03 g 0,0292
N02AA08 Dihydrocodeine (O) 7349,4 g 0,15 g 0,1008
N02AA55 Oxycodone+ Naloxone (O) 691,35 g 75 mg 0,0190
N02AB Phenylpiperidine derivatives 0,1495
N02AB02 Pethidine (P) 469,5 g 0,4 g 0,0024
N02AB02 Pethidine (P, V) 1080 g 0,4 g 0,0056
N02AB03 Fentanyl (O) 2,3068 g
N02AB03 Fentanyl (SL) 2,707 g 0,6 mg 0,0093
N02AB03 Fentanyl (TD) 77,1664 g 1,2 mg 0,1323
N02AE Oripavine derivatives 0,0066
N02AE01 Buprenorphine (TD) 3,8674 g 1,2 mg 0,0066
N02AJ Opioids in combination with non-opioid analgesics 7,6803
N02AJ06 Codeine+ Paracetamol (O) 8948960 pieces 3 pieces 6,1356
N02AJ13 Tramadol+ Paracetamol (O) 2101,125 g 150 mg 0,0288
N02AJ14 Tramadol+ Dexketoprofen (O) 110552,625 g 150 mg 1,5159
N02AX Other opioids 1,7480
N02AX02 Tramadol (O) 252166,5 g 0,3 g 1,7289
N02AX02 Tramadol (P) 2784,5 g 0,3 g 0,0191
N02B OTHER ANALGESICS AND ANTIPYRETICS 27,2658
N02BA Salicylic acid and derivatives 0,9654
N02BA01 Acetylsalicylic acid (O) 1179075,84 g 3 g 0,8084
N02BA01 Acetylsalicylic acid (P) 55 g
N02BA80 Acetylsalicylic acid + Ascorbic acid (O) 229061,6 g 3 g 0,1570
N02BB Pyrazolones 0,0013
N02BB02 Metamizole sodium (P) 1940 g 3 g 0,0013
N02BB86 Metamizole sodium+ Pitofenone (O) 45 g
N02BE Anilides 20,4968
N02BE01 Paracetamol (O) 22407489,7 g 3 g 15,3630
N02BE01 Paracetamol (P) 347624 g 3 g 0,2383
32/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N02BE01 Paracetamol (R) 87891,9 g 3 g 0,0603
N02BE52 Paracetamol+ Pseudoephedrine+ Diphenhydramine (O) 1304 g 3 g 0,0009
N02BE70 Paracetamol+ Ibuprofen (O) 55360 g 3 g 0,0380
N02BE75 Paracetamol+ Guaifenesin+ Phenylephrine (O) 455684 g 3 g 0,3124
N02BE81 Paracetamol+ Chlorphenamine+ Pseudoephedrine+
Dextromethorphan (O) 537804 g 3 g 0,3687
N02BE83 Paracetamol+ Caffeine (O) 414744 g 3 g 0,2844
N02BE84 Paracetamol+ Phenylephrine+ Ascorbic acid (O) 1415825 g 3 g 0,9707
N02BE85 Paracetamol+ Pheniramine+ Ascorbic acid (O) 98530,4 g 3 g 0,0676
N02BE86 Paracetamol+ Phenylephrine+ Terpin hydrate+ Ascorbic
acid+ Caffeine (O) 450402 g 3 g 0,3088
N02BE87 Paracetamol+ Pseudoephedrine (O) 44770 g 3 g 0,0307
N02BE91 Paracetamol+ Ascorbic acid (O) 18044,4 g 3 g 0,0124
N02BE92 Paracetamol+ Codeine (O) 1134150 g 3 g 0,7776
N02BE94 Paracetamol+ Codeine+ Caffeine (O) 1748580 g 3 g 1,1989
N02BE95 Paracetamol+ Phenylephrine (O) 40 g 3 g <0,0001
N02BE97 Paracetamol+ Pseudoephedrine+ Dextromethorphan (O) 677188 g 3 g 0,4643
N02BF Gabapentinoids 5,8021
N02BF01 Gabapentin (O) 2055610 g 1,8 g 2,3489
N02BF02 Pregabalin (O) 503661,2 g 0,3 g 3,4532
N02BG Other analgesics and antipyretics 0,0001
N02BG80 Dronabinol+ Cannabidiol (O) 300 dose 8 dose 0,0001
N02C ANTIMIGRAINE PREPARATIONS 1,2825
N02CC Selective serotonin (5HT1) agonists 1,2494
N02CC01 Sumatriptan (N) 0,84 g 0,02 g 0,0001
N02CC01 Sumatriptan (O) 27151,5 g 0,05 g 1,1169
N02CC03 Zolmitriptan (O) 99,07 g 2,5 mg 0,0815
N02CC04 Rizatriptan (O) 58,44 g 0,01 g 0,0120
N02CC07 Frovatriptan (O) 47,2 g 2,5 mg 0,0388
N02CD Calcitonin gene-related peptide (CGRP) antagonists 0,0332
N02CD01 Erenumab (P) 16,24 g 2,5 mg 0,0134
N02CD03 fremanezumab (P) 72,225 g 7,5 mg 0,0198
N02CD05 Eptinezumab (P) 3,6 g
N03 ANTIEPILEPTICS 7,5127
N03A ANTIEPILEPTICS 7,5127
N03AA Barbiturates and derivatives 0,2960
N03AA02 Phenobarbital (O) 12300 g 0,1 g 0,2530
N03AA02 Phenobarbital (P) 30 g 0,1 g 0,0006
N03AA03 Primidone (O) 25750 g 1,25 g 0,0424
N03AB Hydantoin derivatives 0,0350
N03AB02 Phenytoin (O) 4930 g 0,3 g 0,0338
N03AB02 Phenytoin (P) 172,5 g 0,3 g 0,0012
N03AD Succinimide derivatives 0,0212
N03AD01 Ethosuximide (O) 12862,5 g 1,25 g 0,0212
N03AE Benzodiazepine derivatives 0,5550
N03AE01 Clonazepam (O) 2158,8 g 0,008 g 0,5550
N03AF Carboxamide derivatives 2,5368
N03AF01 Carbamazepine (O) 865440 g 1 g 1,7801
N03AF02 Oxcarbazepine (O) 367665 g 1 g 0,7562
N03AF03 Rufinamide (O) 360 g 1,4 g 0,0005
N03AG Fatty acid derivatives 1,7520
N03AG01 Valproic acid (O) 1267405 g 1,5 g 1,7379
N03AG01 Valproic acid (P) 2113,5 g 1,5 g 0,0029
N03AG04 Vigabatrin (O) 10900 g 2 g 0,0112
N03AX Other antiepileptics 2,3167
N03AX03 Sultiame (O) 3680 g 0,4 g 0,0189
N03AX09 Lamotrigine (O) 145105,8 g 0,3 g 0,9949
N03AX11 Topiramate (O) 40999,5 g 0,3 g 0,2811
33/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N03AX14 Levetiracetam (O) 737722,5 g 1,5 g 1,0116
N03AX14 Levetiracetam (P) 1325 g 1,5 g 0,0018
N03AX15 Zonisamide (O) 74,2 g 0,2 g 0,0008
N03AX17 Stiripentol (O) 795 g 1 g 0,0016
N03AX18 Lacosamide (O) 486,5 g 0,3 g 0,0033
N03AX22 perampanel (O) 2,016 g 8 mg 0,0005
N03AX24 Cannabidiol (O) 720 g 0,7 g 0,0021
N04 ANTI-PARKINSON DRUGS 3,7003
N04A ANTICHOLINERGIC AGENTS 0,5605
N04AA Tertiary amines 0,5605
N04AA01 Trihexyphenidyl (O) 2725,2 g 0,01 g 0,5605
N04B DOPAMINERGIC AGENTS 3,1398
N04BA Dopa and dopa derivatives 1,4919
N04BA03 Levodopa + Carbidopa+ Entacapone (O) 69965 g 0,45 g 0,3198
N04BA80 Levodopa + Benserazide (O) 316250 g 0,6 g 1,0841
N04BA81 Levodopa + Carbidopa (intestin) 21462 g
N04BA81 Levodopa + Carbidopa (O) 25648 g 0,6 g 0,0879
N04BB Adamantane derivatives 0,3004
N04BB01 Amantadine (O) 29210 g 0,2 g 0,3004
N04BB01 Amantadine (P) 4 g
N04BC Dopamine agonists 0,7834
N04BC04 Ropinirole (O) 1082,536 g 0,006 g 0,3711
N04BC05 Pramipexole (O) 487,5675 g 2,5 mg 0,4011
N04BC07 Apomorphine (P) 108,65 g 20 mg 0,0112
N04BD Monoamine oxidase type B inhibitors 0,5641
N04BD02 Rasagiline (O) 274,262 g 0,001 g 0,5641
N05 PSYCHOLEPTICS 46,7668
N05A ANTIPSYCHOTICS 10,7098
N05AA Phenothiazines with aliphatic side-chain 0,1335
N05AA01 Chlorpromazine (O) 8368,125 g 0,3 g 0,0574
N05AA01 Chlorpromazine (P) 26 g 0,1 g 0,0005
N05AA02 Levomepromazine (O) 11017 g 0,3 g 0,0755
N05AA02 Levomepromazine (P) 5 g 0,1 g 0,0001
N05AB Phenothiazines with piperazine structure 0,0825
N05AB02 Fluphenazine (P) 3,125 g 0,001 g 0,0064
N05AB03 Perphenazine (O) 408,4 g 0,03 g 0,0280
N05AB03 Perphenazine (P) 233,712 g 0,01 g 0,0481
N05AC Phenothiazines with piperidine structure 0,0005
N05AC01 Periciazine (O) 12 g 0,05 g 0,0005
N05AD Butyrophenone derivatives 0,9394
N05AD01 Haloperidol (O) 1936,465 g 0,008 g 0,4979
N05AD01 Haloperidol (P) 804,8 g 0,008 g 0,2069
N05AD03 Melperone (O) 32950 g 0,3 g 0,2259
N05AD08 Droperidol (P) 10,525 g 2,5 mg 0,0087
N05AE Indole derivatives 0,0717
N05AE03 Sertindole (O) 551,68 g 0,016 g 0,0709
N05AE04 Ziprasidone (O) 31,2 g 0,08 g 0,0008
N05AF Thioxanthene derivatives 0,8345
N05AF01 Flupentixol (O) 358,65 g 0,006 g 0,1229
N05AF01 Flupentixol (P) 121,88 g 0,004 g 0,0627
N05AF03 Chlorprothixene (O) 28042,5 g 0,3 g 0,1923
N05AF05 Zuclopenthixol (O) 1269 g 0,03 g 0,0870
N05AF05 Zuclopenthixol (P) 41,5 g 0,03 g 0,0028
N05AF05 Zuclopenthixol (P) 2674,6 g 0,015 g 0,3668
N05AH Diazepines, oxazepines, thiazepines and oxepines 6,3317
N05AH02 Clozapine (O) 101269 g 0,3 g 0,6943
N05AH03 Olanzapine (O) 12229,42 g 0,01 g 2,5154
N05AH03 Olanzapine (P) 253,07 g 0,01 g 0,0521
N05AH04 Quetiapine (O) 597006 g 0,4 g 3,0699
N05AL Benzamides 0,1188
N05AL01 Sulpiride (O) 18085,5 g 0,8 g 0,0465
34/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N05AL05 Amisulpride (O) 14052 g 0,4 g 0,0723
N05AN Lithium 0,3573
N05AN01 Lithium (O) 156360 g 0,9 g 0,3573
N05AX Other antipsychotics 1,8399
N05AX08 Risperidone (O) 1751,14 g 0,005 g 0,7204
N05AX08 Risperidone (P) 20,6 g 2,7 mg 0,0157
N05AX12 Aripiprazole (O) 5894,34 g 0,015 g 0,8083
N05AX12 Aripiprazole (P) 5,9377 g 0,015 g 0,0008
N05AX12 Aripiprazole (P) 759,2 g 0,0133 g 0,1174
N05AX13 Paliperidone (P) 104,075 g 2,5 mg 0,0856
N05AX15 Cariprazine (O) 133,77 g 3 mg 0,0917
N05B ANXIOLYTICS 13,3017
N05BA Benzodiazepine derivatives 13,3011
N05BA01 Diazepam (O) 27435,75 g 0,01 g 5,6431
N05BA01 Diazepam (P) 460,1 g 0,01 g 0,0946
N05BA01 Diazepam (R) 58,75 g 0,01 g 0,0121
N05BA06 Lorazepam (O) 1187,55 g 2,5 mg 0,9770
N05BA06 Lorazepam (P) 29 g 2,5 mg 0,0239
N05BA08 Bromazepam (O) 5399,58 g 0,01 g 1,1106
N05BA09 Clobazam (O) 465 g 0,02 g 0,0478
N05BA12 Alprazolam (O) 2613,5325 g 0,001 g 5,3756
N05BA80 Phenazepam (O) 7,9 g 0,001 g 0,0162
N05BB Diphenylmethane derivatives 0,0002
N05BB01 Hydroxyzine (O) 8,25 g 0,075 g 0,0002
N05BE Azaspirodecanedione derivatives 0,0004
N05BE01 Buspirone (O) 5,4 g 0,03 g 0,0004
N05C HYPNOTICS AND SEDATIVES 22,7554
N05CD Benzodiazepine derivatives 0,1578
N05CD02 Nitrazepam (O) 162,3 g 0,005 g 0,0668
N05CD08 Midazolam (O) 69,825 g 0,015 g 0,0096
N05CD08 Midazolam (P) 453,9 g 0,015 g 0,0622
N05CD08 Midazolam (P, R) 140,5 g 0,015 g 0,0193
N05CD14 Remimazolam (P) 0,2 g
N05CF Benzodiazepine related drugs 21,3903
N05CF01 Zopiclone (O) 60417,465 g 7,5 mg 16,5693
N05CF02 Zolpidem (O) 23147,87 g 0,01 g 4,7612
N05CF04 Eszopiclone (O) 58,184 g 2 mg 0,0598
N05CH Melatonin receptor agonists 0,7566
N05CH01 Melatonin (O) 735,72 g 2 mg 0,7566
N05CM Other hypnotics and sedatives 0,4506
N05CM09 Valerianae radix (O) 615330 pieces 3 pieces 0,4219
N05CM18 Dexmedetomidine (P) 13,962 g 1 mg 0,0287
N06 PSYCHOANALEPTICS 51,1844
N06A ANTIDEPRESSANTS 44,4687
N06AA Non-selective monoamine reuptake inhibitors 1,9928
N06AA02 Imipramine (O) 18,75 g 0,1 g 0,0004
N06AA04 Clomipramine (O) 4591,65 g 0,1 g 0,0944
N06AA04 Clomipramine (P) 2,5 g 0,1 g 0,0001
N06AA09 Amitriptyline (O) 58676,5 g 0,075 g 1,6092
N06AA10 Nortriptyline (O) 10527,5 g 0,075 g 0,2887
N06AB Selective serotonin reuptake inhibitors 26,2635
N06AB03 Fluoxetine (O) 40737,16 g 0,02 g 4,1895
N06AB04 Citalopram (O) 14242,04 g 0,02 g 1,4647
N06AB05 Paroxetine (O) 23454 g 0,02 g 2,4121
N06AB06 Sertraline (O) 200415,2 g 0,05 g 8,2445
N06AB08 Fluvoxamine (O) 1557,5 g 0,1 g 0,0320
N06AB10 Escitalopram (O) 48232,66 g 0,01 g 9,9207
N06AF Monoamine oxidase inhibitors, non-selective 0,0111
N06AF04 Tranylcypromine (O) 54 g 0,01 g 0,0111
N06AX Other antidepressants 16,2013
N06AX03 Mianserin (O) 27 g 0,06 g 0,0009
35/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N06AX05 Trazodone (O) 30261 g 0,3 g 0,2075
N06AX11 Mirtazapine (O) 42300,45 g 0,03 g 2,9002
N06AX12 Bupropion (O) 194562 g 0,3 g 1,3340
N06AX14 Tianeptine (O) 22557,375 g 0,0375 g 1,2373
N06AX16 Venlafaxine (O) 240438,75 g 0,1 g 4,9455
N06AX18 Reboxetine (O) 1,12 g 0,008 g 0,0003
N06AX21 Duloxetine (O) 89776,92 g 0,06 g 3,0776
N06AX22 Agomelatine (O) 15804,6 g 0,025 g 1,3003
N06AX26 Vortioxetine (O) 5808,6 g 10 mg 1,1947
N06AX27 Esketamine (N) 11,844 g 8 mg 0,0030
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD
AND NOOTROPICS 2,9768
N06BA Centrally acting sympathomimetics 2,6602
N06BA04 Methylphenidate (O) 36732,48 g 0,03 g 2,5184
N06BA07 Modafinil (O) 1299 g 0,3 g 0,0089
N06BA09 Atomoxetine (O) 5165,72 g 0,08 g 0,1328
N06BA12 Lisdexamfetamine dimesylate (O) 1088,1 g
N06BC Xanthine derivatives
N06BC81 Caffeine citrate (O, P) 53 g
N06BC81 Caffeine citrate (P) 2,5 g
N06BX Other psychostimulants and nootropics 0,3166
N06BX03 Piracetam (O) 352896 g 2,4 g 0,3024
N06BX13 Idebenone (O) 270 g 0,9 g 0,0006
N06BX18 Vinpocetine (O) 99 g 15 mg 0,0136
N06BX83 Aminobutyric acid (O) 31010 g
N06D ANTI-DEMENTIA DRUGS 3,7389
N06DA Anticholinesterases 1,3503
N06DA02 Donepezil (O) 4922,4 g 7,5 mg 1,3500
N06DA03 Rivastigmine (O) 1,26 g 0,009 g 0,0003
N06DA04 Galantamine (O) 0,224 g 0,016 g <0,0001
N06DX Other anti-dementia drugs 2,3886
N06DX01 Memantine (O) 6454,04 g 0,02 g 0,6638
N06DX02 Ginkgo folium (O) 100632 g 0,12 g 1,7249
N06DX80 Cerebrolysin (P) 2,152 g
N07 OTHER NERVOUS SYSTEM DRUGS 12,5625
N07A PARASYMPATHOMIMETICS 0,3781
N07AA Anticholinesterases 0,3781
N07AA01 neostigmine (P) 30,455 g 0,002 g 0,0313
N07AA02 Pyridostigmine bromide (O) 27729 g 0,18 g 0,3169
N07AA03 Distigmine bromide (O) 0,2 g 0,005 g 0,0001
N07AA80 Neostigmine+ Glycopyrronium (P) 14510 ml 1 ml 0,0298
N07AX Other parasympathomimetics
N07AX01 Pilocarpine (O) 1,26 g
N07B DRUGS USED IN ADDICTIVE DISORDERS 3,3609
N07BA Drugs used in nicotine dependence 1,7488
N07BA01 Nicotine (O) 16609,69 g 0,03 g 1,1388
N07BA01 Nicotine (TD) 4152,106 g 0,014 g 0,6100
N07BB Drugs used in alcohol dependence 0,4531
N07BB01 Disulfiram (O) 36510 g 0,2 g 0,3755
N07BB01 Disulfiram (P) 136 g
N07BB03 Acamprosate (O) 279,72 g 2 g 0,0003
N07BB04 Naltrexone (O) 1750 g 50 mg 0,0720
N07BB05 nalmefene (O) 46,368 g 18 mg 0,0053
N07BC Drugs used in opioid dependence 1,1590
N07BC02 Methadone (O) 13523 g 0,025 g 1,1126
N07BC51 Buprenorphine+ Naloxone (SL) 180,537 g 8 mg 0,0464
N07C ANTIVERTIGO PREPARATIONS 8,7896
N07CA Antivertigo preparations 8,7896
N07CA01 Betahistine (O) 88644,48 g 0,024 g 7,5970
N07CA02 Cinnarizine (O) 48326,25 g 0,09 g 1,1044
N07CA03 Flunarizine (O) 9 g 0,01 g 0,0019
36/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N07CA80 Cinnarizine+ Dimenhydrinate (O) 3774,88 g 90 mg 0,0863
N07X OTHER NERVOUS SYSTEM DRUGS 0,0339
N07XX Other nervous system drugs 0,0339
N07XX02 Riluzole (O) 1430,8 g 0,1 g 0,0294
N07XX04 Sodium oxybate (O) 180 g 7,5 g <0,0001
N07XX06 Tetrabenazine (O) 182 g 0,1 g 0,0037
N07XX07 Fampridine (O) 6,72 g 20 mg 0,0007
N07XX14 Edaravone (P) 6,9 g
P ANTIPARASITIC PRODUCTS, INSECTICIDES AND
REPELLENTS 1,0614
P01 ANTIPROTOZOALS 0,8513
P01A AGENTS AGAINST AMOEBIASIS AND OTHER
PROTOZOAL DISEASES 0,1870
P01AB Nitroimidazole derivatives 0,1870
P01AB01 Metronidazole (O) 181845 g 2 g 0,1870
P01AB01 Metronidazole (O, V) 261 g
P01AX Other agents against amoebiasis and other protozoal
diseases <0,0001
P01AX11 Nitazoxanide (O) 6 g 1 g <0,0001
P01B ANTIMALARIALS 0,6643
P01BA Aminoquinolines 0,6490
P01BA02 Hydroxychloroquine (O) 162666 g 0,516 g 0,6484
P01BA03 Primaquine (O) 4,5 g 0,015 g 0,0006
P01BB Biguanides 0,0148
P01BB51 Proguanil+ Atovaquone (O) 1008 pieces 16 pieces 0,0001
P01BB51 Proguanil+ Atovaquone (O) 28500 pieces 4 pieces 0,0147
P01BD Diaminopyrimidines 0,0004
P01BD01 Pyrimethamine (O) 13,5 g 0,075 g 0,0004
P01BE Artemisinin and derivatives, plain 0,0001
P01BE03 Artesunate (P) 14,28 g 0,28 g 0,0001
P02 ANTHELMINTICS 0,2101
P02B ANTITREMATODALS 0,0001
P02BA Quinoline derivatives and related substances 0,0001
P02BA01 Praziquantel (O) 187,2 g 3 g 0,0001
P02C ANTINEMATODAL AGENTS 0,2100
P02CA Benzimidazole derivatives 0,2090
P02CA01 Mebendazole (O) 18880,4 g 0,2 g 0,1942
P02CA03 Albendazole (O) 2880 g 0,4 g 0,0148
P02CF Avermectines 0,0010
P02CF01 Ivermectin (O) 5,73 g 12 mg 0,0010
P03 ECTOPARASITICIDES, INCL. SCABICIDES,
INSECTICIDES AND REPELLENTS
P03A ECTOPARASITICIDES, INCL. SCABICIDES
P03AC Pyrethrines, incl. synthetic compounds
P03AC04 Permethrin (C) 311310 g
P03AX Other ectoparasiticides, incl. scabicides
P03AX01 Benzyl benzoate (C) 253650 g
R RESPIRATORY SYSTEM 112,7122
R01 NASAL PREPARATIONS 48,5930
R01A DECONGESTANTS AND OTHER NASAL
PREPARATIONS FOR TOPICAL USE 45,1979
R01AA Sympathomimetics, plain 28,2963
R01AA05 Oxymetazoline (N) 184,6875 g 0,4 mg 0,9497
R01AA07 Xylometazoline (N) 10636,285 g 0,8 mg 27,3466
R01AB Sympathomimetics, combinations excl. corticosteroids 5,5672
R01AB83 Xylometazoline+ Ipratropium bromide (N) 331170 ml 0,8 ml 0,8515
R01AB85 Xylometazoline+ Dexpanthenol (N) 1834160 ml 0,8 ml 4,7157
R01AC Antiallergic agents, excl. corticosteroids 0,4075
R01AC01 Cromoglicic acid (N) 0,3 g 0,04 g <0,0001
R01AC03 Azelastine (N) 110,95 g 0,56 mg 0,4075
37/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R01AD Corticosteroids 10,9270
R01AD01 Beclometasone (N) 0,66 g 0,4 mg 0,0034
R01AD05 Budesonide (N) 38,86 g 0,2 mg 0,3996
R01AD08 Fluticasone (N) 91,833 g 0,2 mg 0,9444
R01AD09 Mometasone (N) 507,654 g 0,2 mg 5,2208
R01AD12 Fluticasone furoate (N) 203,1018 g 0,11 mg 3,7977
R01AD81 Fluticasone+ Azelastine (N) 1090800 dose 4 dose 0,5609
R01AX Other nasal preparations
R01AX06 Mupirocin (N) 57 g
R01AX83 Retinol+ Tocopherol (N) 145160 ml
R01B NASAL DECONGESTANTS FOR SYSTEMIC USE 3,3951
R01BA Sympathomimetics 3,3951
R01BA02 Pseudoephedrine (O) 233819,64 g 0,24 g 2,0039
R01BA81 Pseudoephedrine+ Triprolidine (O) 45644,16 g 0,24 g 0,3912
R01BA84 Pseudoephedrine+ Guaifenesin (O) 4371,6 g 0,24 g 0,0375
R01BA89 Pseudoephedrine+ Loratadine (O) 15054,48 g 0,24 g 0,1290
R01BA93 Pseudoephedrine+ Cetirizine (O) 97258,56 g 0,24 g 0,8335
R02 THROAT PREPARATIONS 4,0793
R02A THROAT PREPARATIONS 4,0793
R02AA Antiseptics 3,3789
R02AA06 Cetylpyridinium chloride (O) 216 pieces
R02AA82 Benzydamine+ Cetylpyridinium chloride (O) 1671090 ml
R02AA82 Benzydamine+ Cetylpyridinium chloride (O) 3614032 pieces 6 pieces 1,2389
R02AA89 Povidone, iodinated+ Allantoin (O) 527070 ml
R02AA92 Dequalinium+ Cinchocaine (O) 1959760 pieces 6 pieces 0,6718
R02AA94 Amylmetacresol+ Dichlorobenzyl alcohol (O) 672432 pieces 6 pieces 0,2305
R02AA95 Amylmetacresol+ Dichlorobenzyl alcohol+ Levomenthol
(O) 2198400 pieces 6 pieces 0,7536
R02AA96 Amylmetacresol+ Dichlorobenzyl alcohol+ Ascorbic acid
(O) 1411872 pieces 6 pieces 0,4840
R02AX Other throat preparations 0,7004
R02AX01 Flurbiprofen (O) 14982,31 g 44 mg 0,7004
R02AX80 Thymi herba+ Sage leaf (Salvia officinalis) (O) 42975 ml
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES 28,1110
R03A ADRENERGICS, INHALANTS 20,6345
R03AC Selective beta-2-adrenoceptor agonists 3,5820
R03AC02 Salbutamol (I) 916,728 g 0,8 mg 2,3570
R03AC02 Salbutamol (I) 1944,6 g 0,01 g 0,4000
R03AC04 Fenoterol (I) 55,96 g 0,6 mg 0,1918
R03AC12 Salmeterol (I) 2,712 g 0,1 mg 0,0558
R03AC13 Formoterol (I) 4,3049 g 0,024 mg 0,3689
R03AC18 Indacaterol (I) 15,2055 g 0,15 mg 0,2085
R03AK Adrenergics in combination with corticosteroids or other
drugs, excl. anticholinergics 12,8464
R03AK06 Salmeterol+ Fluticasone (I) 448800 dose 4 dose 0,2308
R03AK06 Salmeterol+ Fluticasone (I) 1897200 dose 2 dose 1,9511
R03AK07 Formoterol+ Budesonide (I) 983880 dose 2 dose 1,0118
R03AK07 Formoterol+ Budesonide (I) 6624120 dose 4 dose 3,4062
R03AK08 Formoterol+ Beclometasone (I) 4172040 dose 4 dose 2,1453
R03AK10 Vilanterol+ Fluticasone furoate (I) 1975680 dose 1 dose 4,0637
R03AK13 Salbutamol+ Beclometasone (I) 72800 dose 4 dose 0,0374
R03AL Adrenergics in combinations with anticholinergics incl.
triple combinations with corticosteroids 4,2061
R03AL01 Fenoterol+ Ipratropium bromide (I) 193320 ml 16 ml 0,0249
R03AL01 Fenoterol+ Ipratropium bromide (I) 2595400 dose 6 dose 0,8897
R03AL03 Vilanterol+ Umeclidinium (I) 434220 dose 1 dose 0,8931
R03AL04 Indacaterol+ Glycopyrronium (I) 133650 dose 1 dose 0,2749
R03AL05 Formoterol+ Aclidinium (I) 366480 dose 2 dose 0,3769
R03AL06 Olodaterol+ Tiotropium (I) 627900 dose 2 dose 0,6457
R03AL07 Formoterol+ Glycopyrronium (I) 308280 dose 4 dose 0,1585
R03AL08 Vilanterol+ Umeclidinium+ Fluticasone furoate (I) 132300 dose 1 dose 0,2721
38/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R03AL09 Formoterol+ Glycopyrronium+ Beclometasone (I) 1070520 dose 4 dose 0,5505
R03AL11 Formoterol+ Glycopyrronium+ Budesonide (I) 232800 dose 4 dose 0,1197
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY
DISEASES, INHALANTS 4,5684
R03BA Glucocorticoids 1,6311
R03BA01 Beclometasone (I) 0,2 g 1,5 mg 0,0003
R03BA02 Budesonide (I) 233,16 g 1,5 mg 0,3197
R03BA02 Budesonide (I) 273,104 g 0,8 mg 0,7022
R03BA05 Fluticasone (I) 177,642 g 0,6 mg 0,6090
R03BB Anticholinergics 2,9372
R03BB01 Ipratropium bromide (I) 17,116 g 0,12 mg 0,2934
R03BB01 Ipratropium bromide (I) 30,28 g 0,3 mg 0,2076
R03BB04 Tiotropium (I) 3,1293 g 0,005 mg 1,2873
R03BB05 Aclidinium (I) 119,7647 g 0,644 mg 0,3825
R03BB06 Glycopyrronium (I) 5,4635 g 44 mcg 0,2554
R03BB07 Umeclidinium (I) 13,6653 g 55 mcg 0,5110
R03C ADRENERGICS FOR SYSTEMIC USE 0,1271
R03CC Selective beta-2-adrenoceptor agonists 0,1271
R03CC02 Salbutamol (O) 741,18 g 0,012 g 0,1270
R03CC02 Salbutamol (P) 0,105 g 0,012 g <0,0001
R03D OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE
AIRWAY DISEASES 2,7811
R03DA Xanthines 0,9773
R03DA04 Theophylline (O) 187340 g 0,4 g 0,9633
R03DA05 Aminophylline (O) 22,5 g 0,1 g 0,0005
R03DA05 Aminophylline (P) 3955,2 g 0,6 g 0,0136
R03DC Leukotriene receptor antagonists 1,7105
R03DC03 Montelukast (O) 8316,196 g 0,01 g 1,7105
R03DX Other systemic drugs for obstructive airway diseases 0,0933
R03DX05 Omalizumab (P) 244,95 g 0,016 g 0,0315
R03DX07 Roflumilast (O) 0,03 g 0,5 mg 0,0001
R03DX09 Mepolizumab (P) 61,1 g 3,6 mg 0,0349
R03DX10 Benralizumab (P) 7,02 g 0,54 mg 0,0267
R05 COUGH AND COLD PREPARATIONS 10,6552
R05C EXPECTORANTS, EXCL. COMBINATIONS WITH
COUGH SUPPRESSANTS 10,4046
R05CA Expectorants
R05CA12 Hederae helicis folium (O) 2412,8 g
R05CA12 Hederae helicis folium (O) 350670 pieces
R05CA12 Hederae helicis folium (O) 10077080 ml
R05CA86 Iceland moss (O) 12608100 ml
R05CA87
Distillate form a mixture of rectified essential oils:
eucalyptus oil, sweet orange oil, common myrtle oil,
lemon oil (O)
2963100 pieces
R05CA88 Thymi herba+ Wild thyme+ Plantago (O) 366000 ml
R05CA89 Thymi herba+ Hederae helicis folium (O) 582700 ml
R05CA91 Thymi herba+ Marshmallow root (O) 408620 pieces
R05CA91 Thymi herba+ Marshmallow root (O) 7109070 ml
R05CA92 Thymi herba (O) 207760 pieces
R05CB Mucolytics 10,4046
R05CB01 Acetylcysteine (I, P) 1011 g
R05CB01 Acetylcysteine (O) 1552918,8 g 0,5 g 6,3882
R05CB01 Acetylcysteine (P) 6850,5 g
R05CB02 Bromhexine (O) 9909,04 g 0,024 g 0,8492
R05CB03 Carbocisteine (O) 209465 g 1,5 g 0,2872
R05CB06 Ambroxol (O) 166825,5 g 0,12 g 2,8595
R05CB13 Dornase alfa (I) 24,855 g 2,5 mg 0,0204
R05D COUGH SUPPRESSANTS, EXCL. COMBINATIONS
WITH EXPECTORANTS 0,1212
R05DB Other cough suppressants 0,1212
39/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R05DB09 Oxeladin (O) 4714,45 g 0,08 g 0,1212
R05DB80 Marshmallow root+ Tiliae flos+ Plantago (O) 8748 g
R05F COUGH SUPPRESSANTS AND EXPECTORANTS,
COMBINATIONS 0,1293
R05FA Opium derivatives and expectorants 0,1293
R05FA80 Codeine+ Guaifenesin (O) 1886550 ml 30 ml 0,1293
R05X OTHER COLDPREPARATIONS
R05XA Other cold combination preparations
R05XA80 Gentian root+ Primula flowers+ Rumex acetosa+
Sambucus nigra flower+ Verbena herb (O) 2630920 pieces
R05XA80 Gentian root+ Primula flowers+ Rumex acetosa+
Sambucus nigra flower+ Verbena herb (O) 2804500 ml
R05XA82 Ibuprofen+ Pseudoephedrine (O) 5776,8 g
R06 ANTIHISTAMINES FOR SYSTEMIC USE 21,2726
R06A ANTIHISTAMINES FOR SYSTEMIC USE 21,2726
R06AA Aminoalkyl ethers 0,4369
R06AA02 Diphenhydramine (P) 18,6 g
R06AA04 Clemastine (O) 376,76 g 0,002 g 0,3875
R06AA04 Clemastine (P) 48,09 g 0,002 g 0,0495
R06AE Piperazine derivatives 11,1495
R06AE07 Cetirizine (O) 51785,925 g 0,01 g 10,6516
R06AE09 Levocetirizine (O) 1210,36 g 0,005 g 0,4979
R06AX Other antihistamines for systemic use 9,6861
R06AX02 Cyproheptadine (O) 0,12 g 0,012 g <0,0001
R06AX13 Loratadine (O) 19167,6 g 0,01 g 3,9425
R06AX17 Ketotifen (O) 2,28 g 0,002 g 0,0023
R06AX22 Ebastine (O) 7157,9 g 0,01 g 1,4723
R06AX27 Desloratadine (O) 3293,32 g 0,005 g 1,3548
R06AX28 Rupatadine (O) 966,08 g 0,01 g 0,1987
R06AX29 Bilastine (O) 26404,7 g 20 mg 2,7155
R07 OTHER RESPIRATORY SYSTEM PRODUCTS 0,0012
R07A OTHER RESPIRATORY SYSTEM PRODUCTS 0,0012
R07AA Lung surfactants 0,0003
R07AA81 Phospholipid fraction, porcine lung (endotrach) 22,2 g 0,16 g 0,0003
R07AX Other respiratory system products 0,0009
R07AX02 ivacaftor (O) 130,2 g 0,3 g 0,0009
R07AX32 Ivacaftor+ Tezacaftor+ Elexacaftor (O) 155,4 g
S SENSORY ORGANS 35,0366
S01 OPHTHALMOLOGICALS 35,0366
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA01 Chloramphenicol (S) 253890 ml
S01AA12 Tobramycin (S) 37000 ml
S01AA12 Tobramycin (S) 55947,5 g
S01AA13 Fusidic acid (S) 57820 g
S01AD Antivirals
S01AD03 Aciclovir (S) 3915 g
S01AE Fluoroquinolones
S01AE03 Ciprofloxacin (S) 11,88 g
S01AE03 Ciprofloxacin (S) 13710 ml
S01AE05 Levofloxacin (S) 34065 ml
S01AE07 Moxifloxacin (S) 18235 ml
S01AX Other antiinfectives
S01AX15 Propamidine (S) 210 ml
S01AX18 Povidone, iodinated (S) 552 ml
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA01 Dexamethasone (S) 265 pieces
S01BA01 Dexamethasone (S) 22093 g
S01BA01 Dexamethasone (S) 155020 ml
S01BA02 Hydrocortisone (S) 3351 g
40/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
S01BA04 Prednisolone (S) 0,325 g
S01BA09 Clobetasone (S) 49280 ml
S01BA14 Loteprednol (S) 5675 ml
S01BC Antiinflammatory agents, non-steroids
S01BC03 Diclofenac (S) 30 ml
S01BC05 Ketorolac (S) 10000 ml
S01BC10 Nepafenac (S) 22305 ml
S01BC11 Bromfenac (S) 19230 ml
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES
IN COMBINATION
S01CA Corticosteroids and antiinfectives in combination
S01CA80 Dexamethasone+ Neomycin+ Polymyxin B (S) 82025 ml
S01CA81 Dexamethasone+ Tobramycin (S) 16495,5 g
S01CA81 Dexamethasone+ Tobramycin (S) 41260 ml
S01CA82 Dexamethasone+ Chloramphenicol (S) 55205,5 g
S01CA82 Dexamethasone+ Chloramphenicol (S) 511320 ml
S01CA84 Dexamethasone+ Levofloxacin (S) 7140 ml
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS 35,0366
S01EA Sympathomimetics in glaucoma therapy 0,0312
S01EA05 Brimonidine (S) 3030 ml 0,2 ml 0,0312
S01EB Parasympathomimetics 0,0191
S01EB01 Pilocarpine (S) 3200 ml 0,4 ml 0,0165
S01EB02 Carbachol (S) 510 ml 0,4 ml 0,0026
S01EC Carbonic anhydrase inhibitors 3,7624
S01EC01 Acetazolamide (O) 26065 g 0,75 g 0,0715
S01EC01 Acetazolamide (P) 336 g 0,75 g 0,0009
S01EC03 Dorzolamide (S) 150840 ml 0,3 ml 1,0342
S01EC04 Brinzolamide (S) 153490 ml 0,2 ml 1,5785
S01EC80 Brinzolamide+ Brimonidine (S) 104750 ml 0,2 ml 1,0773
S01ED Beta blocking agents 24,0230
S01ED01 Timolol (S) 25110 ml 0,2 ml 0,2582
S01ED01 Timolol (S) 233580 g 40 mg 12,0110
S01ED02 Betaxolol (S) 75795 ml 0,2 ml 0,7795
S01ED80 Timolol+ Dorzolamide (S) 304195 ml 0,2 ml 3,1284
S01ED81 Timolol+ Travoprost (S) 33010 ml 0,2 ml 0,3395
S01ED82 Timolol+ Bimatoprost (S) 100092 ml 0,2 ml 1,0294
S01ED83 Timolol+ Brinzolamide (S) 226220 ml 0,2 ml 2,3265
S01ED84 Timolol+ Latanoprost (S) 75582,5 ml 0,2 ml 0,7773
S01ED85 Timolol+ Tafluprost (S) 327994 ml 0,2 ml 3,3732
S01EE Prostaglandin analogues 7,2010
S01EE01 Latanoprost (S) 266235 ml 0,1 ml 5,4761
S01EE03 Bimatoprost (S) 153 ml 0,1 ml 0,0031
S01EE04 Travoprost (S) 51247,5 ml 0,1 ml 1,0541
S01EE05 Tafluprost (S) 97389 ml 0,3 ml 0,6677
S01F MYDRIATICS AND CYCLOPLEGICS
S01FA Anticholinergics
S01FA01 Atropine (S) 525 ml
S01FA04 Cyclopentolate (S) 34070 ml
S01FA06 Tropicamide (S) 15405 ml
S01FA80 Tropicamide+ Phenylephrine+ Lidocaine (int.cam) 300 pieces
S01FB Sympathomimetics excl. antiglaucoma preparations
S01FB01 Phenylephrine (S) 9435 ml
S01G DECONGESTANTS AND ANTIALLERGICS
S01GA Sympathomimetics used as decongestants
S01GA02 Tetryzoline (S) 209505 ml
S01GX Other antiallergics
S01GX01 Cromoglicic acid (S) 114020 ml
S01GX07 Azelastine (S) 46938 ml
S01GX09 Olopatadine (S) 48930 ml
S01H LOCAL ANESTHETICS
41/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
S01HA Local anesthetics
S01HA02 Oxybuprocaine (S) 500 ml
S01HA03 Tetracaine (S) 27100 ml
S01HA04 Proxymetacaine (S) 34980 ml
S01J DIAGNOSTIC AGENTS
S01JA Colouring agents
S01JA01 Fluorescein (P) 4560 ml
S01JA81 Fluorescein+ Oxybuprocaine+ Chlorobutanol (S) 2985 ml
S01K SURGICAL AIDS
S01KA Viscoelastic substances
S01KA02 Hypromellose (S) 6540 ml
S01L OCULAR VASCULAR DISORDER AGENTS
S01LA Antineovascularisation agents
S01LA05 aflibercept (S) 196 pieces
S01LA06 Brolucizumab (S) 135 pieces
S01X OTHER OPHTHALMOLOGICALS
S01XA Other ophthalmologicals
S01XA03 Sodium chloride (S) 658 g
S01XA18 Ciclosporin (S) 18936 ml
S01XA80 Retinol+ Dexpanthenol (S) 6849,5 g
S01XA81 Carbomer (S) 174150 g
S01XA82 Hypromellose (S) 205240 ml
S01XA85 Hypromellose+ Dextran (S) 504105 ml
S02 OTOLOGICALS
S02C CORTICOSTEROIDS AND ANTIINFECTIVES IN
COMBINATION
S02CA Corticosteroids and antiinfectives in combination
S02CA81 Dexamethasone+ Neomycin+ Acetic acid, glacial (A) 3840 ml
S02CA82 Hydrocortisone+ Ciprofloxacin (A) 146870 ml
S02D OTHER OTOLOGICALS
S02DA Analgesics and anesthetics
S02DA81 Phenazone+ Lidocaine (A) 2100 ml
V VARIOUS 0,1892
V01 ALLERGENS
V01A ALLERGENS
V01AA Allergen extracts
V01AA02 Grass pollen allergen extract (O) 146 pieces
V01AA02 Grass pollen allergen extract (P) 243 pieces
V01AA03 House dust mites (O) 115 pieces
V01AA03 House dust mites (P) 327 pieces
V01AA05 Tree pollen allergen extract (P) 289 pieces
V01AA05 Tree pollen allergen extract (SL) 210 pieces
V01AA07 Allergen extracts - insects (P) 594 pieces
V01AA11 Allergen extracts - animals (O) 24 pieces
V01AA80 Tree and grass pollen (O) 48 pieces
V01AA80 Tree and grass pollen (P) 7 pieces
V01AA83 Grass pollen allergen extract+ Flowers (O) 4 pieces
V01AA84 Tree and flower pollen (O) 10 pieces
V03 ALL OTHER THERAPEUTIC PRODUCTS 0,1892
V03A ALL OTHER THERAPEUTIC PRODUCTS 0,1892
V03AB Antidotes
V03AB06 Sodium thiosulfate (P) 625 g
V03AB14 Protamine sulfate (P) 266,75 g
V03AB15 Naloxone (N) 3,492 g
V03AB15 Naloxone (P) 2,558 g
V03AB16 Ethanol (P) 10600 ml
V03AB17 Methylthioninium chloride (P) 148,1 g
V03AB19 Physostigmine (P) 0,16 g
V03AB21 Potassium iodide (O) 12381,2 g
V03AB24 Digitalis antitoxin (P) 2,8 g
42/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
V03AB25 Flumazenil (P) 0,09 g
V03AB32 Glutathione (P) 4212 g
V03AB33 Hydroxocobalamin (P) 100 g
V03AB34 Fomepizole (P) 20 g
V03AB35 Sugammadex (P) 148 g
V03AB37 Idarucizumab (P) 210 g
V03AB80 Sodium calcium edetate (P) 1050 g
V03AC Iron chelating agents
V03AC01 Deferoxamine (P) 65 g
V03AC02 Deferiprone (O) 550 g
V03AC03 Deferasirox (O) 3985,2 g
V03AE Drugs for treatment of hyperkalemia and
hyperphosphatemia 0,1412
V03AE01 Polystyrene sulfonate (O, R) 1638448,5 g 45 g 0,0749
V03AE02 Sevelamer (O) 147456 g 6,4 g 0,0474
V03AE03 Lanthanum (O) 20722,5 g 2,25 g 0,0189
V03AF Detoxifying agents for antineoplastic treatment 0,0480
V03AF01 Mesna (P) 4122 g
V03AF03 Calcium folinate (O) 44,1 g 0,06 g 0,0015
V03AF07 Rasburicase (P) 0,729 g 0,014 g 0,0001
V03AF10 Sodium levofolinate (P) 676,65 g 0,03 g 0,0464
V03AH Drugs for treatment of hypoglycemia
V03AH01 Diazoxide (O) 50 g
V03AN Medical gases
V03AN01 Oxygen (I) 464275000 ml
V03AN05 Air, medicinal (I) 5630000 ml
V03AX Other therapeutic products
V03AX81 herbal preparation (C) 33000 g
V03AX81 herbal preparation (O) 680190 pieces
V03AX81 herbal preparation (O) 9012440 ml
V03AX82 homeopathic preparations (A) 479 pieces
V03AX82 homeopathic preparations (C) 13626 pieces
V03AX82 homeopathic preparations (O) 1516295 pieces
V04 DIAGNOSTIC AGENTS
V04C OTHER DIAGNOSTIC AGENTS
V04CD Tests for pituitary function
V04CD01 Metyrapone (O) 25 g
V04CD04 Corticorelin (P) 0,0002 g
V04CF Tuberculosis diagnostics
V04CF01 Tuberculin (P) 5520 U
V04CJ Tests for thyreoidea function
V04CJ02 Protirelin (P) 0,008 g
V04CX Other diagnostic agents
V04CX01 Indocyanine green (P) 7,9 g
V04CX03 Methacholine (I) 67,554 g
V04CX04 Mannitol (I) 102 pieces
V04CX06 Hexaminolevulinate (P) 21,08 g
V04CX09 Patent blue (P) 4 g
V04CX87 Carbon monoxide+ Helium (I) 60000 ml
V04CX89 Carbon monoxide+ Acetylene+ Methane+ Oxygen+
Nitrogen (I) 340000 ml
V07 ALL OTHER NON-THERAPEUTIC PRODUCTS
V07A ALL OTHER NON-THERAPEUTIC PRODUCTS
V07AB Solvents and diluting agents, incl. irrigating solutions
V07AB80 Sodium chloride (P) 9892335 ml
V07AB83 Water for injection (NA) 24650600 ml
V07AB83 Water for injection (P) 2000 ml
V08 CONTRAST MEDIA
V08A X-RAY CONTRAST MEDIA, IODINATED
43/44
Estonian Statistics on Medicines 2022
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
V08AA Watersoluble, nephrotropic, high osmolar X-ray contrast
media
V08AA01 Sodium amidotrizoate+ Meglumine Amidotrizoate (P) 4000 ml
V08AB Watersoluble, nephrotropic, low osmolar X-ray contrast
media
V08AB02 Iohexol (P) 2051030 g
V08AB05 Iopromide (P) 1234938,5 g
V08AB09 Iodixanol (P) 3264700 g
V08AD Non-watersoluble X-ray contrast media
V08AD01 Ethyl esters of iodised fatty acids from poppyseed oil (P) 264 g
V08B X-RAY CONTRAST MEDIA, NON-IODINATED
V08BA Barium sulfate containing X-ray contrast media
V08BA01 Barium sulfate (O) 283,2 pieces
V08BA01 Barium sulfate (O) 134000 ml
V08C MAGNETIC RESONANCE IMAGING CONTRAST
MEDIA
V08CA Paramagnetic contrast media
V08CA01 Gadopentetic acid (P) 4780 ml
V08CA02 Gadoteric acid (P) 75750 ml
V08CA09 Gadobutrol (P) 116275 ml
V08CA10 Gadoxetic acid (P) 6780 ml
V08D ULTRASOUND CONTRAST MEDIA
V08DA Ultrasound contrast media
V08DA05 Sulfur hexafluoride (P) 275 ml
V09 DIAGNOSTIC RADIOPHARMACEUTICALS
V09A CENTRAL NERVOUS SYSTEM
V09AB Iodine (123I) compounds
V09AB03 Ioflupane (123I) (P) 455 ml
V09F THYROID
V09FX Various thyroid diagnostic radiopharmaceuticals
V09FX01 Technetium (99mTc)pertechnetate (S) 71 pieces
V10 THERAPEUTIC RADIOPHARMACEUTICALS
V10X OTHER THERAPEUTIC RADIOPHARMACEUTICALS
V10XA Iodine (131I) compounds
V10XA01 Sodium iodide (131I) (O) 129 pieces
44/44
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A ALIMENTARY TRACT AND METABOLISM 184,6875
A01 STOMATOLOGICAL PREPARATIONS 0,0691
A01A STOMATOLOGICAL PREPARATIONS 0,0691
A01AB Antiinfectives and antiseptics for local oral treatment 0,0691
A01AB08 Neomycin(O) 200 pieces
A01AB09 Miconazole(O) 6699,2 g 0,2 g 0,0691
A01AB12 Hexetidine(O) 1386880 ml
A01AB82 Demeclocycline+Triamcinolone(dental) 770 g
A01AD Other agents for local oral treatment
A01AD80 Lidocaine+Cetylpyridinium chloride(gingival) 199970 g
A01AD81 Lidocaine+Cetrimide(O) 50250 g
A01AD82 Choline salicylate(O) 160048 pieces
A01AD83 Lidocaine+Chamomille extract(O) 386240 g
A01AD90 Lidocaine+Paraformaldehyde(dental) 198 g
A02 DRUGS FOR ACID RELATED DISORDERS 61,1483
A02A ANTACIDS 1,2544
A02AD Combinations and complexes of aluminium, calcium and
magnesium compounds 1,2544
A02AD81 Aluminium hydroxide+Magnesium hydroxide(O) 950000 pieces 10 pieces 0,1959
A02AD81 Aluminium hydroxide+Magnesium hydroxide(O) 4863894 ml 50 ml 0,2006
A02AD83 Calcium carbonate+Magnesium carbonate(O) 4160664 pieces 10 pieces 0,8580
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-
OESOPHAGEAL REFLUX DISEASE (GORD) 59,8939
A02BA H2-receptor antagonists 0,0212
A02BA02 Ranitidine(P) 1971,75 g 0,3 g 0,0136
A02BA03 Famotidine(O) 148 g 0,04 g 0,0076
A02BC Proton pump inhibitors 59,8616
A02BC01 Omeprazole(O) 303243,2 g 0,02 g 31,2654
A02BC02 Pantoprazole(O) 303796,5 g 0,04 g 15,6612
A02BC02 Pantoprazole(P) 395,6 g 0,04 g 0,0204
A02BC03 Lansoprazole(O) 13,86 g 0,03 g 0,0010
A02BC05 Esomeprazole(O) 184510,48 g 0,03 g 12,6824
A02BC05 Esomeprazole(P) 3364 g 0,03 g 0,2312
A02BC08 Vonoprazan(O) 4 g
A02BD Combinations for eradication of Helicobacter pylori 0,0016
A02BD08 Bismuth subcitrate+Tetracycline+Metronidazole (O) 9600 pieces 12 pieces 0,0016
A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux
disease (GORD) 0,0094
A02BX02 Sucralfate(O) 15790 g 4 g 0,0081
A02BX03 Pirenzepine(O) 60 g 0,1 g 0,0012
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL
DISORDERS 8,5944
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL
DISORDERS 7,6949
A03AA Synthetic anticholinergics, esters with tertiary amino group 1,4436
A03AA04 Mebeverine(O) 210024 g 0,3 g 1,4436
A03AD Papaverine and derivatives 4,6591
A03AD01 Papaverine hydrochloride(P) 102 g 0,1 g 0,0021
A03AD02 Drotaverine(O) 222498,4 g 0,1 g 4,5881
A03AD02 Drotaverine(P) 3344 g 0,1 g 0,0690
A03AX Other drugs for functional gastrointestinal disorders 1,5921
A03AX13 Simeticone(O) 386047,5729 g 0,5 g 1,5921
A03B BELLADONNA AND DERIVATIVES, PLAIN 0,0823
A03BA Belladonna alkaloids, tertiary amines 0,0710
A03BA01 Atropine(O, P) 17,52 g 0,0015 g 0,0241
A03BA01 Atropine(P) 34,16 g 0,0015 g 0,0470
A03BB Belladonna alkaloids, semisynthetic, quaternary ammonium
compounds 0,0112
A03BB01 Hyoscine butylbromide(O) 30,4 g 0,06 g 0,0010
A03BB01 Hyoscine butylbromide(P) 296,6 g 0,06 g 0,0102
1/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A03F PROPULSIVES 0,8173
A03FA Propulsives 0,8173
A03FA01 Metoclopramide(O) 10122,5 g 0,03 g 0,6958
A03FA01 Metoclopramide(P) 1544,8 g 0,03 g 0,1062
A03FA03 Domperidone(O) 222,9 g 0,03 g 0,0153
A04 ANTIEMETICS AND ANTINAUSEANTS 0,1167
A04A ANTIEMETICS AND ANTINAUSEANTS 0,1167
A04AA Serotonin (5-HT3) antagonists 0,1082
A04AA01 Ondansetron(P) 185,74 g 0,016 g 0,0239
A04AA02 Granisetron(O) 56,95 g 0,002 g 0,0587
A04AA02 Granisetron(P) 34,23 g 0,003 g 0,0235
A04AA80 Palonosetron+Netupitant(O) 963 pieces 1 pieces 0,0020
A04AD Other antiemetics 0,0086
A04AD01 Scopolamine(TD) 45 pieces 1 pieces 0,0001
A04AD12 Aprepitant(O) 233,985 g 0,165 g 0,0029
A04AD81 Fosaprepitant(P) 256,05 g 0,095 g 0,0056
A05 BILE AND LIVER THERAPY 2,0206
A05A BILE THERAPY 0,5389
A05AA Bile acids and derivatives 0,5389
A05AA02 Ursodeoxycholic acid(O) 195987,5 g 0,75 g 0,5389
A05B LIVER THERAPY, LIPOTROPICS 1,4818
A05BA Liver therapy 1,4818
A05BA03 Silymarin(O) 2076650 pieces
A05BA80 Phospholipids from Soya Beans(O) 1349910 pieces 3 pieces 0,9279
A05BA80 Phospholipids from Soya Beans(O) 1611640 pieces 6 pieces 0,5539
A05BA80 Phospholipids from Soya Beans(P) 1045 pieces
A06 DRUGS FOR CONSTIPATION 17,0341
A06A DRUGS FOR CONSTIPATION 17,0341
A06AB Contact laxatives 7,3954
A06AB02 Bisacodyl(O) 14101,2 g 0,01 g 2,9078
A06AB02 Bisacodyl(R) 719,6 g 0,01 g 0,1484
A06AB06 Senna glycosides(O) 4880 pieces 1 pieces 0,0101
A06AB08 Sodium picosulfate(O) 10490,3565 g 0,005 g 4,3264
A06AB80 Sodium picosulfate+Magnesium oxide+Citric acid(O) 2768 pieces 2 pieces 0,0029
A06AD Osmotically acting laxatives 8,6893
A06AD11 Lactulose(O) 26737036,2 g 6,7 g 8,2289
A06AD15 Macrogol(O) 2232640 g 10 g 0,4604
A06AD80 Macrogol+Sodium citrate+Citric acid+Sodium
chloride+Potassium chloride(O) 28200 ml
A06AD81 Sodium sulphate, anhydrous+Potassium chloride+Sodium
chloride+Macrogol+Sodium hydrogen carbonate(O) 33932 pieces
A06AD83
Macrogol+Sodium sulphate, anhydrous+Sodium
chloride+Potassium chloride+Ascorbic acid+Sodium
ascorbate(O)
5859 pieces
A06AD85 Sodium sulphate, anhydrous+magnesium sulfate
heptahydrate+Potassium sulphate(O) 825088 ml
A06AG Enemas 0,9134
A06AG11 Laurilsulfate, incl. combinations+Sorbitol+Sodium citrate(R) 442972 pieces 1 pieces 0,9134
A06AH Peripheral opioid receptor antagonists 0,0359
A06AH03 Naloxegol(O) 435,75 g 25 mg 0,0359
A07 ANTIDIARRHEALS, INTESTINAL
ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS 4,2629
A07A INTESTINAL ANTIINFECTIVES 0,0027
A07AA Antibiotics 0,0027
A07AA02 Nystatin(O) 120000000 U 1500000 U 0,0002
A07AA11 Rifaximin(O) 698,4 g 0,6 g 0,0024
A07AA12 Fidaxomicin(O) 28 g 0,4 g 0,0001
A07B INTESTINAL ADSORBENTS 0,3750
A07BC Other intestinal adsorbents 0,3750
2/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A07BC05 Diosmectidum(O) 1636560 g 9 g 0,3750
A07C ELECTROLYTES WITH CARBOHYDRATES
A07CA Oral rehydration salt formulations
A07CA80 Sodium chloride+Potassium chloride+Sodium
citrate+Glucose(O) 67280 pieces
A07D ANTIPROPULSIVES 0,9140
A07DA Antipropulsives 0,9140
A07DA03 Loperamide(O) 4432,352 g 0,01 g 0,9140
A07E INTESTINAL ANTIINFLAMMATORY AGENTS 2,3751
A07EA Corticosteroids acting locally 0,0096
A07EA06 Budesonide(O) 42,03 g 0,009 g 0,0096
A07EA06 Budesonide(R) 1,0304 g
A07EC Aminosalicylic acid and similar agents 2,3655
A07EC01 Sulfasalazine(O) 802500 g 2 g 0,8274
A07EC02 Mesalazine(O) 1022258 g 1,5 g 1,4053
A07EC02 Mesalazine(R) 96600 g 1,5 g 0,1328
A07F ANTIDIARRHEAL MICROORGANISMS 0,5961
A07FA Antidiarrheal microorganisms 0,5961
A07FA02 Saccharomyces boulardii(O) 289067,5 g 1 g 0,5961
A07X OTHER ANTIDIARRHEALS
A07XA Other antidiarrheals
A07XA04 Racecadotril(O) 2480 g
A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0543
A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0543
A08AA Centrally acting antiobesity products 0,0538
A08AA62 Bupropione+Naltrexone(O) 104272 pieces 4 pieces 0,0538
A08AB Peripherally acting antiobesity products 0,0005
A08AB01 Orlistat(O) 95,76 g 0,36 g 0,0005
A09 DIGESTIVES, INCL. ENZYMES 1,6877
A09A DIGESTIVES, INCL. ENZYMES 1,6877
A09AA Enzyme preparations 1,6875
A09AA02 Lipase+Amylase+Protease(O) 3273341 pieces 4 pieces 1,6875
A09AC Enzyme and acid preparations, combinations 0,0002
A09AC80 Pepsin+Betaine(O) 300 pieces 3 pieces 0,0002
A10 DRUGS USED IN DIABETES 66,9614
A10A INSULINS AND ANALOGUES 15,9557
A10AB Insulins and analogues for injection, fast-acting 6,0469
A10AB01 Insulin (human)(P) 1110000 U 40 U 0,0572
A10AB04 Insulin lispro(P) 21273000 U 40 U 1,0967
A10AB05 Insulin aspart(P) 82890000 U 40 U 4,2731
A10AB06 Insulin glulisine(P) 12024000 U 40 U 0,6199
A10AC Insulins and analogues for injection, intermediate-acting 0,0653
A10AC01 Insulin (human)(P) 1266000 U 40 U 0,0653
A10AD Insulins and analogues for injection, intermediate- or long-
acting combined with fast-acting 0,8005
A10AD04 Insulin lispro(P) 4824000 U 40 U 0,2487
A10AD05 Insulin aspart(P) 10704000 U 40 U 0,5518
A10AE Insulins and analogues for injection, long-acting 9,0431
A10AE04 Insulin glargine(P) 95778000 U 40 U 4,9375
A10AE05 Insulin detemir(P) 41920500 U 40 U 2,1611
A10AE06 Insulin degludec(P) 33693900 U 40 U 1,7370
A10AE54 Insulin glargine+Lixisenatide(P) 4026000 U 40 U 0,2075
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS 51,0057
A10BA Biguanides 21,2264
A10BA02 Metformin(O) 20587506 g 2 g 21,2264
A10BB Sulfonylureas 12,2232
A10BB01 Glibenclamide(O) 0,018 g 0,01 g <0,0001
A10BB07 Glipizide(O) 855,9 g 0,01 g 0,1765
3/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A10BB09 Gliclazide(O) 205800 g 0,06 g 7,0729
A10BB12 Glimepiride(O) 4824,12 g 0,002 g 4,9738
A10BD Combinations of oral blood glucose lowering drugs 7,6158
A10BD07 Metformin+Sitagliptin(O) 1793120 pieces 2 pieces 1,8488
A10BD08 Metformin+Vildagliptin(O) 1392960 pieces 2 pieces 1,4362
A10BD10 Metformin+Saxagliptin(O) 315960 pieces 2 pieces 0,3258
A10BD11 Metformin+Linagliptin(O) 1196340 pieces 2 pieces 1,2335
A10BD15 Metformin+Dapagliflozin(O) 789208 pieces 2 pieces 0,8137
A10BD19 Linagliptin+Empagliflozin(O) 183900 pieces 1 pieces 0,3792
A10BD20 Metformin+Empagliflozin(O) 1343460 pieces 2 pieces 1,3852
A10BD21 Saxagliptin+Dapagliflozin(O) 92624 pieces 1 pieces 0,1910
A10BD23 Metformin+Ertugliflozin(O) 1232 pieces 1 pieces 0,0025
A10BF Alpha glucosidase inhibitors 0,0011
A10BF01 Acarbose(O) 162,75 g 0,3 g 0,0011
A10BG Thiazolidinediones 0,1208
A10BG03 Pioglitazone(O) 1757,7 g 0,03 g 0,1208
A10BH Dipeptyl peptidase 4 (DPP-4) inhibitors 4,1024
A10BH01 Sitagliptin(O) 48127,1 g 0,1 g 0,9924
A10BH02 Vildagliptin(O) 8460 g 0,1 g 0,1745
A10BH03 Saxagliptin(O) 538,35 g 5 mg 0,2220
A10BH05 Linagliptin(O) 6579,6 g 5 mg 2,7135
A10BJ Glucagon-like peptide-1 (GLP-1) analogues 2,9082
A10BJ01 Exenatide(P) 5,224 g 0,286 mg 0,0377
A10BJ02 Liraglutide(P) 639,36 g 1,5 mg 0,8789
A10BJ03 Lixisenatide(P) 0,5677 g 20 mcg 0,0585
A10BJ05 Dulaglutide(P) 24,786 g 0,16 mg 0,3194
A10BJ06 Semaglutide(P) 86,079 g 0,11 mg 1,6136
A10BK Sodium-glucose co-transporter 2 (SGLT2) inhibitors 2,8077
A10BK01 Dapagliflozin(O) 5586,3 g 10 mg 1,1519
A10BK03 empagliflozin(O) 14047,35 g 17,5 mg 1,6552
A10BK04 Ertugliflozin(O) 2,52 g 10 mg 0,0005
A11 VITAMINS 13,2321
A11A MULTIVITAMINS, COMBINATIONS 1,5026
A11AA Multivitamins with minerals 1,5026
A11AA03 Multivitamins+Mineral elements(O) 728670 pieces 1 pieces 1,5026
A11B MULTIVITAMINS, PLAIN 0,0001
A11BA Multivitamins, plain 0,0001
A11BA80 Multivitamins(O) 500 ml 10 ml 0,0001
A11C VITAMIN A AND D, INCL. COMBINATIONS OF THE TWO 3,8756
A11CC Vitamin D and analogues 3,8756
A11CC04 Calcitriol(O) 0,1007 g 0,001 mg 0,2077
A11CC05 Colecalciferol(O) 711500000 U 400 U 3,6679
A11CC05 Colecalciferol(P) 7500000 U
A11D VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN
B6 AND B12 1,6079
A11DA Vitamin B1, plain 0,4309
A11DA01 Thiamine(O, P, V) 1050 g 0,05 g 0,0433
A11DA01 Thiamine(P) 9398,5 g 0,05 g 0,3876
A11DA03 Benfotiamine(O) 1754230 pieces
A11DB Vitamin B1 in combination with vitamin B6 and/or vitamin B12 1,1770
A11DB80 Thiamine+Pyridoxine(P) 2345 pieces 1 pieces 0,0048
A11DB81 Benfotiamine+Pyridoxine(O) 207900 pieces 3 pieces 0,1429
A11DB84 Thiamine+Pyridoxine+Cyanocobalamin(O) 428260 pieces 1 pieces 0,8831
A11DB85 Thiamine+Pyridoxine+Cyanocobalamin+Lidocaine(P) 70895 pieces 1 pieces 0,1462
A11E VITAMIN B-COMPLEX, INCL. COMBINATIONS 0,6892
A11EA Vitamin B-complex, plain 0,6892
A11EA80 Thiamine+Nicotinamide+Riboflavin+Calcium
pantothenate+Pyridoxine(O) 334250 pieces 1 pieces 0,6892
A11G ASCORBIC ACID (VITAMIN C), INCL. COMBINATIONS 0,1285
A11GA Ascorbic acid (vitamin C), plain 0,1285
4/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A11GA01 Ascorbic acid(P) 12460 g 0,2 g 0,1285
A11H OTHER PLAIN VITAMIN PREPARATIONS 0,0545
A11HA Other plain vitamin preparations 0,0545
A11HA02 Pyridoxine(O) 90 g 0,16 g 0,0012
A11HA02 Pyridoxine(P) 3746,5 g 0,16 g 0,0483
A11HA03 Tocopherol(O) 120 g 0,2 g 0,0012
A11HA03 Tocopherol(P) 10,5 g 0,2 g 0,0001
A11HA08 Tocofersolan(O) 363 g 0,2 g 0,0037
A11J OTHER VITAMIN PRODUCTS, COMBINATIONS 5,3736
A11JA Combinations of vitamins
A11JA80 Combinations of vitamins(O) 800 ml
A11JB Vitamins with minerals 5,3736
A11JB81 Pyridoxine+Magnesium(O) 6924650 pieces 4 pieces 3,5698
A11JB82
Thiamine+Riboflavin+Pyridoxine+Cyanocobalamin+Ascorbic
acid+Biotin+Nicotinamide+Calcium
pantothenate+Calcium+Magnesium+Folic acid+Zinc(O)
874785 pieces 1 pieces 1,8039
A12 MINERAL SUPPLEMENTS 8,9424
A12A CALCIUM 5,3412
A12AA Calcium 0,8646
A12AA03 Calcium gluconate(P) 36475 g 3 g 0,0251
A12AA04 Calcium carbonate(O) 1221425 g 3 g 0,8396
A12AX Calcium, combinations with vitamin D and/or other drugs 4,4766
A12AX80 Calcium+Colecalciferol(O) 573690 pieces 1 pieces 1,1830
A12AX80 Calcium+Colecalciferol(O) 3194460 pieces 2 pieces 3,2936
A12B POTASSIUM 3,1279
A12BA Potassium 3,1279
A12BA01 Potassium chloride(O) 357570 g 3 g 0,2458
A12BA02 Potassium citrate(O) 2484 g 4 g 0,0013
A12BA80 Potassium chloride+Potassium hydrogen carbonate(O) 7200 pieces
A12BA81 Potassium aspartate+Magnesium aspartate(O) 4151450 pieces 3 pieces 2,8535
A12BA81 Potassium aspartate+Magnesium aspartate(P) 13255 pieces 1 pieces 0,0273
A12C OTHER MINERAL SUPPLEMENTS 0,4733
A12CC Magnesium 0,4733
A12CC04 Magnesium citrate(O) 459040,2 g 2 g 0,4733
A12CX Other mineral products
A12CX83 Phosphate(O) 11900 pieces
A14 ANABOLIC AGENTS FOR SYSTEMIC USE 0,0030
A14A ANABOLIC STEROIDS 0,0030
A14AB Estren derivatives 0,0030
A14AB01 Nandrolone(P) 2,95 g 0,002 g 0,0030
A14B OTHER ANABOLIC AGENTS
A14BX Other anabolic agents
A14BX80 Riboxine(O) 90 g
A16 OTHER ALIMENTARY TRACT AND METABOLISM
PRODUCTS 0,5605
A16A OTHER ALIMENTARY TRACT AND METABOLISM
PRODUCTS 0,5605
A16AA Amino acids and derivatives 0,0018
A16AA01 Levocarnitine(O) 1750 g 2 g 0,0018
A16AA02 Ademetionine(O) 280 g
A16AA81 Glycine(O) 480 g
A16AB Enzymes 0,0056
A16AB02 Imiglucerase(P) 162800 U 300 U 0,0011
A16AB03 Agalsidase alfa(P) 1,281 g 0,001 g 0,0026
A16AB04 Agalsidase beta(P) 1,69 g 0,005 g 0,0007
A16AB07 Alglucosidase alfa(P) 55,4 g 0,1 g 0,0011
A16AB09 Idursulfase(P) 1,152 g
A16AX Various alimentary tract and metabolism products 0,5531
A16AX01 Thioctic acid(O) 157770 g 0,6 g 0,5422
A16AX01 Thioctic acid(P) 177 g 0,6 g 0,0006
5/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A16AX03 Sodium phenylbutyrate(O) 2250 g 20 g 0,0002
A16AX05 Zinc(O) 618,75 g 0,15 g 0,0085
A16AX07 Sapropterin(O) 720 g
A16AX10 Eliglustat(O) 108,192 g 0,168 g 0,0013
A16AX15 Telotristat(O) 67,5 g 0,75 g 0,0002
A16AX80 Creatine(O) 450 g
A16AX81 Copper histidine(P) 0,23 g
B BLOOD AND BLOOD FORMING ORGANS 109,6746
B01 ANTITHROMBOTIC AGENTS 82,5895
B01A ANTITHROMBOTIC AGENTS 82,5895
B01AA Vitamin K antagonists 2,0593
B01AA03 Warfarin(O) 7490 g 0,0075 g 2,0593
B01AB Heparin group 3,1858
B01AB01 Heparin sodium(P) 604000000 U 10000 U 0,1245
B01AB05 Enoxaparin sodium(hem, P) 762976000 U 2000 U 0,7867
B01AB05 Enoxaparin sodium(P) 1755668000 U 2000 U 1,8102
B01AB06 Nadroparin calcium(P) 7353000 U 2850 U 0,0053
B01AB12 Bemiparin sodium(P) 556640000 U 2500 U 0,4591
B01AC Platelet aggregation inhibitors, excl. heparin 54,7718
B01AC04 Clopidogrel(O) 155659,2 g 0,075 g 4,2797
B01AC06 Acetylsalicylic acid (O) 4273554 pieces 1 pieces 8,8124
B01AC11 Iloprost(I) 0,089 g 0,15 mg 0,0012
B01AC11 Iloprost(P) 0,0047 g 50 mcg 0,0002
B01AC16 Eptifibatide(P) 62,94 g 0,2 g 0,0006
B01AC24 Ticagrelor(O) 98666,4 g 0,18 g 1,1303
B01AC27 Selexipag
(O) 3,12 g 1,8 mg 0,0036
B01AC80 Acetylsalicylic acid +Magnesium oxide(O) 19661700 pieces 1 pieces 40,5438
B01AD Enzymes 0,0026
B01AD01 Streptokinase(P) 12500000 U 1500000 U <0,0001
B01AD02 Alteplase(P) 108,02 g 0,1 g 0,0022
B01AD11 Tenecteplase(P) 7,45 g 0,04 g 0,0004
B01AE Direct thrombin inhibitors 2,7382
B01AE07 Dabigatran etexilate(O) 398360,15 g 0,3 g 2,7382
B01AF Direct factor Xa inhibitors 19,8302
B01AF01 Rivaroxaban(O) 102828,25 g 0,02 g 10,6019
B01AF02 Apixaban(O) 43141,8 g 10 mg 8,8961
B01AF03 Edoxaban(O) 9665,1 g 60 mg 0,3322
B01AX Other antithrombotic agents 0,0015
B01AX01 Defibrotide(P) 66 g 1,75 g 0,0001
B01AX05 Fondaparinux sodium(P) 1,75 g 0,0025 g 0,0014
B02 ANTIHEMORRHAGICS 0,1855
B02A ANTIFIBRINOLYTICS 0,1578
B02AA Amino acids 0,1578
B02AA01 Aminocaproic acid(P) 6515 g 16 g 0,0008
B02AA02 Tranexamic acid(O) 111570 g 2 g 0,1150
B02AA02 Tranexamic acid(P) 40637,5 g 2 g 0,0419
B02B VITAMIN K AND OTHER HEMOSTATICS 0,0277
B02BA Vitamin K 0,0037
B02BA01 Phytomenadione(O) 1,5 g 0,02 g 0,0002
B02BA01 Phytomenadione(O, P) 23,3 g 0,02 g 0,0024
B02BA01 Phytomenadione(P) 11,12 g 0,02 g 0,0011
B02BB Fibrinogen 0,0001
B02BB01 Fibrinogen human(P) 262 g 5 g 0,0001
B02BC Local hemostatics
B02BC81 Fibrinogen human+Human thrombin(epil) 687 pieces
B02BD Blood coagulation factors
B02BD01 Human prothrombin complex(P) 207200 U
B02BD02 Human coagulation factor VIII(P) 3485000 U
B02BD03 Factor VIII inhibitor bypassing activity(P) 120000 U
B02BD04 Human coagulation factor IX(P) 726800 U
6/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B02BD05 Human coagulation factor VII(P) 192000 U
B02BD06 Von Willebrand factor, human+Human coagulation factor
VIII(P) 2075250 U
B02BD08 Coagulation factor VIIa(P) 6050000 U
B02BD80 Turoctocog alfa(P) 40000 U
B02BD81 Simoctocog alfa(P) 414000 U
B02BD83 Efmoroctocog alfa(P) 2870750 U
B02BX Other systemic hemostatics 0,0239
B02BX01 Etamsylate(P) 625 g
B02BX04 Romiplostim(P) 0,0718 g 30 mcg 0,0049
B02BX05 Eltrombopag(O) 390,6 g 50 mg 0,0161
B02BX06 Emicizumab(P) 21,045 g 15 mg 0,0029
B03 ANTIANEMIC PREPARATIONS 26,8983
B03A IRON PREPARATIONS 4,2523
B03AA Iron bivalent, oral preparations 2,3296
B03AA07 Ferrous sulphate(O) 225945 g 0,2 g 2,3296
B03AB Iron trivalent, oral preparations
B03AB80 Iron (III) hydroxide polymaltose complex(O) 83378,5 g
B03AC Iron, parenteral preparations 0,1080
B03AC01 Dextriferron(P) 1274 g 0,1 g 0,0263
B03AC02 Iron (III) hydroxide sucrose complex(P) 1351,5 g 0,1 g 0,0279
B03AC06 Iron (III)-hydroxide dextran complex(P) 1534 g 0,1 g 0,0316
B03AC80 Ferric derisomaltose(P) 1076,5 g 0,1 g 0,0222
B03AD Iron in combination with folic acid 1,8147
B03AD02 Ferrous fumarate+Folic acid(O) 508550 pieces 1 pieces 1,0487
B03AD03 Ferrous sulphate+Folic acid(O) 371500 pieces 1 pieces 0,7661
B03AE Iron in other combinations
B03AE81 Ferrous gluconate+Manganese gluconate+Copper
gluconate(O) 1696000 ml
B03AE82 Ferrous fumarate+Folic acid+Ascorbic acid(O) 43600 pieces
B03B VITAMIN B12 AND FOLIC ACID 21,6311
B03BA Vitamin B12 (cyanocobalamin and analogues) 6,4352
B03BA01 Cyanocobalamin(O) 7,9 g 1 mg 0,0163
B03BA01 Cyanocobalamin(P) 62,055 g 0,02 mg 6,3981
B03BA03 Hydroxocobalamin(P) 0,2016 g 0,02 mg 0,0208
B03BB Folic acid and derivatives 15,1959
B03BB01 Folic acid(O) 2947,7 g 0,4 mg 15,1959
B03X OTHER ANTIANEMIC PREPARATIONS 1,0149
B03XA Other antianemic preparations 1,0149
B03XA02 Darbepoetin alfa(P) 1,6123 g 0,0045 mg 0,7388
B03XA03 Methoxy polyethylene glycol-epoetin beta(P) 0,292 g 4 mcg 0,1505
B03XA80 Epoetin beta(P) 60912000 U 1000 U 0,1256
B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B05A BLOOD AND RELATED PRODUCTS
B05AA Blood substitutes and plasma protein fractions
B05AA01 Albumin(P) 701430 g
B05AA06 Gelatin agents(P) 8840000 ml
B05AA81 Dextran+Sodium chloride(P) 23500 ml
B05AA83 Gelatine+Sodium chloride+Potassium chloride+Magnesium
chloride+Sodium lactate(P) 670000 ml
B05AA86 human plasma proteins(P) 505400 ml
B05B I.V. SOLUTIONS
B05BA Solutions for parenteral nutrition
B05BA01 Amino acids(P) 799000 ml
B05BA02 Fat emulsions(P) 156900 ml
B05BA03 Carbohydrates(P) 7160 g
B05BA03 Carbohydrates(P) 67562600 ml
B05BA10 Combinations(P) 17156734 ml
B05BB Solutions affecting the electrolyte balance
B05BB01 Electrolytes(P) 188802500 ml
B05BB81 Sodium chloride+Glucose(P) 250000 ml
7/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B05BC Solutions producing osmotic diuresis
B05BC01 Mannitol(P) 954000 ml
B05C IRRIGATING SOLUTIONS
B05CX Other irrigating solutions
B05CX10 Combinations(NA) 346000 ml
B05D PERITONEAL DIALYTICS
B05DA Isotonic solutions
B05DA80 Isotonic solutions(P) 8830000 ml
B05DB Hypertonic solutions
B05DB80 hypertonic solutions(P) 138214000 ml
B05DB81 Amino acids+Sodium chloride+Calcium chloride
dihydrate+Magnesium chloride hexahydrate+Sodium lactate(P) 220000 ml
B05Z HEMODIALYTICS AND HEMOFILTRATES
B05ZB Hemofiltrates
B05ZB80
Sodium chloride+Potassium chloride+Calcium chloride
dihydrate+Magnesium chloride+Glucose+Sodium hydrogen
carbonate(P)
20430000 ml
B05ZB82
Calcium chloride dihydrate+Magnesium chloride
hexahydrate+Sodium chloride+Sodium hydrogen
carbonate+Potassium chloride+Disodium phosphate
dihydrate(P)
9150000 ml
B05ZB84
Calcium chloride dihydrate+Magnesium chloride
hexahydrate+Lactic acid+Sodium hydrogen carbonate+Sodium
chloride(P)
1020000 ml
B05ZB85 Sodium citrate+Sodium chloride(P) 2017000 ml
B05ZB86
Magnesium chloride hexahydrate+Sodium chloride+Potassium
chloride+Disodium phosphate dihydrate+Sodium hydrogen
carbonate(P)
7080000 ml
B05X I.V. SOLUTION ADDITIVES
B05XA Electrolyte solutions
B05XA01 Potassium chloride(P) 1650 g
B05XA01 Potassium chloride(P) 3601200 ml
B05XA02 Sodium hydrogen carbonate(P) 1765500 ml
B05XA03 Sodium chloride(P) 491307700 ml
B05XA05 Magnesium sulphate(P) 416900 ml
B05XA07 Calcium chloride(P) 168500 ml
B05XA14 Sodium glycerophosphate, hydrated(P) 105600 ml
B05XA80 Electrolytes(P) 137700 ml
B05XB Amino acids
B05XB01 Arginine(P) 3300 ml
B05XB02 Alanyl glutamine(P) 45000 ml
B05XC Vitamins
B05XC80 Vitamins(P) 3597,52 g
B05XC80 Vitamins(P) 183400 ml
B06 OTHER HEMATOLOGICAL AGENTS 0,0014
B06A OTHER HEMATOLOGICAL AGENTS 0,0014
B06AA Enzymes
B06AA03 Hyaluronidase(P) 90640 U
B06AB Heme products
B06AB01 Hemin(P) 40 ml
B06AB80 hemoderivate of calf blood, deproteinized(O) 100 pieces
B06AC Drugs usedin hereditary angioedema 0,0014
B06AC01 C1-inhibitor(P) 486000 U 1400 U 0,0007
B06AC02 Icatibant(P) 8,1 g 0,03 g 0,0006
B06AC04 Conestat alfa(P) 163800 U 3500 U 0,0001
C CARDIOVASCULAR SYSTEM 450,0066
C01 CARDIAC THERAPY 21,9418
C01A CARDIAC GLYCOSIDES 2,0279
C01AA Digitalis glycosides 2,0279
C01AA05 Digoxin(O) 243,6725 g 0,25 mg 2,0099
8/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C01AA05 Digoxin(P) 2,145 g 0,25 mg 0,0177
C01AA06 Lanatoside C(O) 0,18 g 0,001 g 0,0004
C01B ANTIARRHYTHMICS, CLASS I AND III 5,3353
C01BA Antiarrhythmics, class Ia <0,0001
C01BA01 Quinidine(O) 20 g 1,2 g <0,0001
C01BA13 Hydroquinidine(O) 234 g
C01BB Antiarrhythmics, class Ib 0,0235
C01BB02 Mexiletine(O) 100 g 0,8 g 0,0003
C01BB80 Aethacizin(O) 2257,5 g 0,2 g 0,0233
C01BC Antiarrhythmics, class Ic 3,4495
C01BC03 Propafenone(O) 478569 g 0,3 g 3,2895
C01BC03 Propafenone(P) 548,45 g 0,3 g 0,0038
C01BC04 Flecainide(O) 15113 g 0,2 g 0,1558
C01BC04 Flecainide(P) 39 g 0,2 g 0,0004
C01BD Antiarrhythmics, class III 1,8622
C01BD01 Amiodarone(O) 174018 g 0,2 g 1,7942
C01BD01 Amiodarone(P) 5400,75 g 0,2 g 0,0557
C01BD07 Dronedarone(O) 4800 g 0,8 g 0,0124
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES 0,6378
C01CA Adrenergic and dopaminergic agents 0,6363
C01CA01 Etilefrine(O) 1,8375 g 0,05 g 0,0001
C01CA02 Isoprenaline(P) 0,65 g 0,09 g <0,0001
C01CA03 Norepinephrine(P) 400,9 g 0,006 g 0,1378
C01CA04 Dopamine(P) 2606,6 g 0,5 g 0,0107
C01CA06 Phenylephrine(P) 211,7 g 0,004 g 0,1091
C01CA07 Dobutamine(P) 1491,25 g 0,5 g 0,0062
C01CA17 Midodrine(O) 6,45 g 0,03 g 0,0004
C01CA24 Epinephrine(I) 4,392 g
C01CA24 Epinephrine(intraoss, P) 0,05 g 0,5 mg 0,0002
C01CA24 Epinephrine(P) 80,152 g 0,5 mg 0,3306
C01CA26 Ephedrine(P) 998 g 0,05 g 0,0412
C01CE Phosphodiesterase inhibitors 0,0009
C01CE02 Milrinone(P) 21,38 g 0,05 g 0,0009
C01CX Other cardiac stimulants 0,0006
C01CX08 Levosimendan(P) 3,25 g 11 mg 0,0006
C01CX80 Ammonia(I) 1381960 ml
C01D VASODILATORS USED IN CARDIAC DISEASES 5,8804
C01DA Organic nitrates 5,8772
C01DA02 Glyceryl trinitrate(P) 206,7 g
C01DA02 Glyceryl trinitrate(SL) 507,812 g 0,0025 g 0,4189
C01DA05 Pentaerithrityl tetranitrate(O) 3 g 0,12 g 0,0001
C01DA08 Isosorbide dinitrate(O) 644 g 0,06 g 0,0221
C01DA08 Isosorbide dinitrate(SL) 236,35 g 0,02 g 0,0244
C01DA14 Isosorbide mononitrate(O) 104977,4 g 0,04 g 5,4118
C01DX Other vasodilatators used in cardiac diseases 0,0032
C01DX80 Meldonium(O) 1155 g 0,75 g 0,0032
C01DX80 Meldonium(P) 25 g 0,75 g 0,0001
C01E OTHER CARDIAC PREPARATIONS 8,0604
C01EA Prostaglandins 0,0002
C01EA01 Alprostadil(P) 0,0556 g 0,5 mg 0,0002
C01EB Other cardiac preparations 8,0602
C01EB10 Adenosine(P) 109,104 g 0,015 g 0,0150
C01EB15 Trimetazidine(O) 147291,9 g 0,04 g 7,5931
C01EB16 Ibuprofen(P) 1,16 g 0,03 g 0,0001
C01EB17 Ivabradine(O) 1774,92 g 0,01 g 0,3660
C01EB18 Ranolazine(O) 61890 g 1,5 g 0,0851
C01EB21 Regadenoson(P) 0,168 g 0,4 mg 0,0009
C01EB80 Hawthorn berry(O) 63440 ml
C02 ANTIHYPERTENSIVES 4,0447
C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING 2,4305
C02AC Imidazoline receptor agonists 2,4305
9/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C02AC01 Clonidine(O) 5,7075 g 0,45 mg 0,0262
C02AC01 Clonidine(P) 2,783 g 0,45 mg 0,0128
C02AC02 Guanfacine(O) 0,084 g 3 mg 0,0001
C02AC05 Moxonidine(O) 347,9358 g 0,3 mg 2,3916
C02C ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING 1,5733
C02CA Alpha-adrenoreceptor antagonists 1,5733
C02CA01 Prazosin(O) 3,56 g 0,005 g 0,0015
C02CA04 Doxazosin(O) 3049,028 g 0,004 g 1,5718
C02D ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON 0,0011
C02DD Nitroferricyanide derivatives 0,0011
C02DD01 Sodium nitroprusside(P) 25,47 g 0,05 g 0,0011
C02K OTHER ANTIHYPERTENSIVES 0,0399
C02KX Antihypertensives for pulmonary arterial hypertension 0,0399
C02KX01 Bosentan(O) 1505 g 0,25 g 0,0124
C02KX02 Ambrisentan(O) 48,75 g 7,5 mg 0,0134
C02KX04 Macitentan(O) 4,5 g 10 mg 0,0009
C02KX05 Riociguat(O) 28,623 g 4,5 mg 0,0131
C03 DIURETICS 27,3596
C03A LOW-CEILING DIURETICS, THIAZIDES 1,3934
C03AA Thiazides, plain 1,3934
C03AA03 Hydrochlorothiazide(O) 16893,5 g 0,025 g 1,3934
C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES 2,3642
C03BA Sulfonamides, plain 2,3642
C03BA11 Indapamide(O) 2866,35 g 2,5 mg 2,3642
C03C HIGH-CEILING DIURETICS 20,2193
C03CA Sulfonamides, plain 20,2193
C03CA01 Furosemide(O) 68271,8 g 0,04 g 3,5195
C03CA01 Furosemide(P) 6259,9 g 0,04 g 0,3227
C03CA04 Torasemide(O) 118656,9 g 0,015 g 16,3119
C03CA04 Torasemide(P) 474,1 g 0,015 g 0,0652
C03D POTASSIUM-SPARING AGENTS 3,3628
C03DA Aldosterone antagonists 3,3628
C03DA01 Spironolactone(O) 122271,25 g 0,075 g 3,3618
C03DA04 Eplerenone(O) 24,75 g 0,05 g 0,0010
C03E DIURETICS AND POTASSIUM-SPARING AGENTS IN
COMBINATION 0,0199
C03EA Low-ceiling diuretics and potassium-sparing agents 0,0199
C03EA81 Hydrochlorothiazide+Amiloride(O) 9630 pieces 1 pieces 0,0199
C04 PERIPHERAL VASODILATORS 2,6475
C04A PERIPHERAL VASODILATORS 2,6475
C04AC Nicotinic acid and derivatives 0,0006
C04AC01 Nicotinic acid(P) 54 g 0,2 g 0,0006
C04AD Purine derivatives 1,6190
C04AD02 Xantinol nicotinate(O) 81 g 0,9 g 0,0002
C04AD03 Pentoxifylline(O) 783720 g 1 g 1,6161
C04AD03 Pentoxifylline(P) 403,5 g 0,3 g 0,0028
C04AX Other peripheral vasodilators 1,0279
C04AX21 Naftidrofuryl(O) 299090 g 0,6 g 1,0279
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL
FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA82 Hydrocortisone+Cinchocaine(R) 64212 pieces
C05AA84 Fluocortolone+Lidocaine(R) 118650 pieces
C05AA84 Fluocortolone+Lidocaine(R) 244530 g
C05AE Muscle relaxants
C05AE01 Glyceryl trinitrate(R) 30 g
C05AX Other agents for treatment of hemorrhoids and anal fissures for
topical use
C05AX81 Xeroformium+Zinc sulphate+Extract of Belladonna(R) 1870 pieces
C05AX83 Yeast cell extract+Shark liver oil(R) 321900 pieces
10/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C05B ANTIVARICOSE THERAPY
C05BA Heparins or heparinoids for topical use
C05BA03 Heparin sodium(C) 7321300 g
C05BB Sclerosing agents for local injection
C05BB02 Lauromacrogol 400(P) 55,425 g
C05BB04 Sodium tetradecyl sulphate(P) 0,3 g
C05C CAPILLARY STABILIZING AGENTS
C05CA Bioflavonoids
C05CA01 Rutoside(O) 204810 pieces
C05CA03 Diosmin(O) 455430 g
C05CA04 Troxerutin(C) 3592900 g
C05CA04 Troxerutin(O) 205860 g
C05CA53 Diosmin+Hesperidine(O) 2700 pieces
C05CX Other capillary stabilizing agents
C05CX80 Vigne rouge extract(O) 54 g
C05CX81 Aescin(O) 80 pieces
C07 BETA BLOCKING AGENTS 56,9879
C07A BETA BLOCKING AGENTS 56,9871
C07AA Beta blocking agents, non-selective 1,6890
C07AA05 Propranolol(O) 49375,4 g 0,16 g 0,6363
C07AA07 Sotalol(O) 81674,4 g 0,16 g 1,0526
C07AB Beta blocking agents, selective 54,5936
C07AB02 Metoprolol(O) 1991991,45 g 0,15 g 27,3841
C07AB02 Metoprolol(P) 106,55 g 0,15 g 0,0015
C07AB03 Atenolol(O) 18654,75 g 0,075 g 0,5129
C07AB07 Bisoprolol(O) 17943,6 g 0,01 g 3,7001
C07AB09 Esmolol(P) 0,5 g 2,5 g <0,0001
C07AB12 Nebivolol(O) 55757,03 g 0,005 g 22,9950
C07AG Alpha and beta blocking agents 0,7046
C07AG01 Labetalol(O) 27670 g 0,6 g 0,0951
C07AG01 Labetalol(P) 1475,5 g 0,6 g 0,0051
C07AG02 Carvedilol(O) 10992 g 0,0375 g 0,6044
C07B BETA BLOCKING AGENTS AND THIAZIDES 0,0007
C07BB Beta blocking agents, selective, and thiazides 0,0007
C07BB07 Bisoprolol+Hydrochlorothiazide(O) 360 pieces 1 pieces 0,0007
C08 CALCIUM CHANNEL BLOCKERS 46,4845
C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY
VASCULAR EFFECTS 45,0090
C08CA Dihydropyridine derivatives 45,0090
C08CA01 Amlodipine(O) 63552,75 g 0,005 g 26,2100
C08CA02 Felodipine(O) 6126,975 g 0,005 g 2,5268
C08CA05 Nifedipine(O) 14290,72 g 0,03 g 0,9823
C08CA06 Nimodipine(O) 402 g 0,3 g 0,0028
C08CA06 Nimodipine(P) 3,65 g 0,05 g 0,0002
C08CA08 Nitrendipine(O) 42779,64 g 0,02 g 4,4107
C08CA09 Lacidipine(O) 6126,624 g 0,004 g 3,1584
C08CA13 Lercanidipine(O) 37427,4 g 0,01 g 7,7178
C08D SELECTIVE CALCIUM CHANNEL BLOCKERS WITH DIRECT
CARDIAC EFFECTS 1,4755
C08DA Phenylalkylamine derivatives 1,3680
C08DA01 Verapamil(O) 159208 g 0,24 g 1,3679
C08DA01 Verapamil(P) 13,85 g 0,24 g 0,0001
C08DB Benzothiazepine derivatives 0,1075
C08DB01 Diltiazem(O) 12508,2 g 0,24 g 0,1075
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM 210,3541
C09A ACE INHIBITORS, PLAIN 75,8991
C09AA ACE inhibitors, plain 75,8991
C09AA01 Captopril(O) 923,5 g 0,05 g 0,0381
C09AA02 Enalapril(O) 40891,23 g 0,01 g 8,4321
C09AA02 Enalapril(P) 9,5688 g 0,01 g 0,0020
C09AA03 Lisinopril(O) 5,04 g 0,01 g 0,0010
11/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C09AA04 Perindopril(O) 14762,7 g 0,004 g 7,6104
C09AA05 Ramipril(O) 66657,77 g 2,5 mg 54,9811
C09AA09 Fosinopril(O) 34269,2 g 0,015 g 4,7110
C09AA10 Trandolapril(O) 119,616 g 0,002 g 0,1233
C09B ACE INHIBITORS, COMBINATIONS 56,7495
C09BA ACE inhibitors and diuretics 29,2415
C09BA02 Enalapril+Hydrochlorothiazide(O) 2792120 pieces 1 pieces 5,7575
C09BA04 Perindopril+Indapamide(O) 9573390 pieces 1 pieces 19,7410
C09BA05 Ramipril+Hydrochlorothiazide(O) 1235530 pieces 1 pieces 2,5477
C09BA09 Fosinopril+Hydrochlorothiazide(O) 579612 pieces 1 pieces 1,1952
C09BB ACE inhibitors and calcium channel blockers 12,8524
C09BB03 Lisinopril+Amlodipine(O) 847020 pieces 1 pieces 1,7466
C09BB04 Perindopril+Amlodipine(O) 4185870 pieces 1 pieces 8,6315
C09BB07 Ramipril+Amlodipine(O) 903030 pieces 1 pieces 1,8621
C09BB10 Trandolapril+Verapamil(O) 296856 pieces 1 pieces 0,6121
C09BX ACE inhibitors, other combinations 14,6556
C09BX01 Perindopril+Amlodipine+Indapamide(O) 7107240 pieces 1 pieces 14,6556
C09C ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS), PLAIN 43,2749
C09CA Angiotensin II receptor blockers (ARBs), plain 43,2749
C09CA01 Losartan(O) 85044 g 0,05 g 3,5073
C09CA02 Eprosartan(O) 840 g 0,6 g 0,0029
C09CA03 Valsartan(O) 170325,12 g 0,08 g 4,3903
C09CA06 Candesartan(O) 41969,312 g 0,008 g 10,8179
C09CA07 Telmisartan(O) 413416,96 g 0,04 g 21,3123
C09CA08 Olmesartan medoxomil(O) 31464,44 g 0,02 g 3,2441
C09D ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS),
COMBINATIONS 34,4306
C09DA Angiotensin II receptor blockers (ARBs) and diuretics 15,8037
C09DA01 Losartan+Hydrochlorothiazide(O) 790330 pieces 1 pieces 1,6297
C09DA03 Valsartan+Hydrochlorothiazide(O) 899388 pieces 1 pieces 1,8546
C09DA06 Candesartan+Hydrochlorothiazide(O) 1151244 pieces 1 pieces 2,3739
C09DA07 Telmisartan+Hydrochlorothiazide(O) 4563908 pieces 1 pieces 9,4111
C09DA08 Olmesartan medoxomil+Hydrochlorothiazide(O) 259140 pieces 1 pieces 0,5344
C09DB Angiotensin II receptor blockers (ARBs) and calcium channel
blockers 13,5511
C09DB01 Valsartan+Amlodipine(O) 216428 pieces 1 pieces 0,4463
C09DB02 Olmesartan medoxomil+Amlodipine(O) 3087112 pieces 1 pieces 6,3658
C09DB04 Telmisartan+Amlodipine(O) 3201632 pieces 1 pieces 6,6020
C09DB07 Candesartan+Amlodipine(O) 66416 pieces 1 pieces 0,1370
C09DX Angiotensin II receptor blockers (ARBs), other combinations 5,0759
C09DX01 Valsartan+Amlodipine+Hydrochlorothiazide(O) 2352 pieces 1 pieces 0,0048
C09DX03 Olmesartan medoxomil+Amlodipine+Hydrochlorothiazide(O) 2176244 pieces 1 pieces 4,4876
C09DX04 Valsartan+Sacubitril(O) 282940 pieces 1 pieces 0,5834
C10 LIPID MODIFYING AGENTS 80,1865
C10A LIPID MODIFYING AGENTS, PLAIN 77,9115
C10AA HMG CoA reductase inhibitors 76,7312
C10AA01 Simvastatin(O) 67853,92 g 0,03 g 4,6640
C10AA03 Pravastatin(O) 4074 g 0,03 g 0,2800
C10AA04 Fluvastatin(O) 15836,8 g 0,06 g 0,5443
C10AA05 Atorvastatin(O) 295816,2 g 0,02 g 30,4997
C10AA07 Rosuvastatin(O) 197584,23 g 0,01 g 40,7432
C10AB Fibrates 0,6614
C10AB05 Fenofibrate(O) 64152 g 0,2 g 0,6614
C10AC Bile acid sequestrants 0,0012
C10AC01 Colestyramine(O) 7800 g 14 g 0,0011
C10AC02 Colestipol(O) 250 g 20 g <0,0001
C10AX Other lipid modifying agents 0,5177
C10AX09 Ezetimibe(O) 2427,32 g 0,01 g 0,5005
12/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C10AX13 Evolocumab(P) 58,94 g 10 mg 0,0122
C10AX14 Alirocumab(P) 13,2 g 5,4 mg 0,0050
C10AX80 Omega-3-acid ethyl esters 90(O) 188944 pieces
C10B LIPID MODIFYING AGENTS, COMBINATIONS 2,2750
C10BA Combinations of various lipid modifying agents 1,5405
C10BA05 Atorvastatin+Ezetimibe(O) 18660 pieces 1 pieces 0,0385
C10BA06 Rosuvastatin+Ezetimibe(O) 728400 pieces 1 pieces 1,5020
C10BX Lipid modifying agents in combination with other drugs 0,7345
C10BX03 Atorvastatin+Amlodipine(O) 83250 pieces 1 pieces 0,1717
C10BX11 Atorvastatin+Amlodipine+Perindopril(O) 213330 pieces 1 pieces 0,4399
C10BX13 Rosuvastatin+Perindopril+Indapamide(O) 37800 pieces 1 pieces 0,0779
C10BX15 Atorvastatin+Perindopril(O) 21840 pieces 1 pieces 0,0450
D DERMATOLOGICALS 1,7338
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE 1,0595
D01A ANTIFUNGALS FOR TOPICAL USE
D01AC Imidazole and triazole derivatives
D01AC01 Clotrimazole(C) 569708,6 g
D01AC05 Isoconazole(C) 261742,01 g
D01AC08 Ketoconazole(C) 723219 g
D01AC08 Ketoconazole(C) 773160 ml
D01AC80 Isoconazole+Diflucortolone(C) 435645 g
D01AC81 Clotrimazole+Hexamidine(C) 145020 g
D01AE Other antifungals for topical use
D01AE14 Ciclopirox(C) 1762,2 ml
D01AE15 Terbinafine(C) 586469 g
D01AE16 Amorolfine(C) 29580 ml
D01AE22 Naftifine(C) 182360 ml
D01AE22 Naftifine(C) 233895 g
D01B ANTIFUNGALS FOR SYSTEMIC USE 1,0595
D01BA Antifungals for systemic use 1,0595
D01BA01 Griseofulvin(O) 977,5 g 0,5 g 0,0040
D01BA02 Terbinafine(O) 127966 g 0,25 g 1,0555
D02 EMOLLIENTS AND PROTECTIVES
D02A EMOLLIENTS AND PROTECTIVES
D02AB Zinc products
D02AB80 Zinc oxide(C) 408780 g
D02AE Carbamide products
D02AE01 Urea(C) 78150 g
D02AF Salicylic acid preparations
D02AF81 Salicylic acid+Lactic acid(C) 2009,01 g
D02B PROTECTIVES AGAINST UV-RADIATION
D02BA Protectives against UV-radiation for topical use
D02BA01 4-Aminobenzoic acid(O) 9720 g
D03 PREPARATIONS FOR TREATMENT OF WOUNDS AND
ULCERS
D03A CICATRIZANTS
D03AX Other cicatrizants
D03AX03 Dexpanthenol(C) 3814745 g
D03AX81 Heparin sodium+Allantoin+Extract of Cepae(C) 115500 g
D03AX83 Dexpanthenol+Chlorhexidine(C) 1914240 g
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS,
ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS,
ETC.
D04AA Antihistamines for topical use
D04AA09 Chloropyramine(P) 10 g
D05 ANTIPSORIATICS 0,0534
D05A ANTIPSORIATICS FOR TOPICAL USE
D05AA Tars
D05AA85 Coal tar+Salicylic acid(C) 588000 ml
D05AC Antracen derivatives
13/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D05AC01 Dithranol(C) 4550 g
D05AX Other antipsoriatics for topical use
D05AX02 Calcipotriol(C) 210 g
D05AX80 Calcipotriol+Betamethasone(C) 853350 g
D05B ANTIPSORIATICS FOR SYSTEMIC USE 0,0534
D05BB Retinoids for treatment of psoriasis 0,0534
D05BB02 Acitretin(O) 906,3 g 0,035 g 0,0534
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR
DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE
D06AX Other antibiotics for topical use
D06AX01 Fusidic acid(C) 210705 g
D06AX09 Mupirocin(C) 2310 g
D06AX80 Bacitracin+Neomycin(C) 155540 g
D06AX84 Chloramphenicol+Methyluracil(C) 4000 g
D06B CHEMOTHERAPEUTICS FOR TOPICAL USE
D06BA Sulfonamides
D06BA01 Silver sulfadiazine(C) 1533900 g
D06BB Antivirals
D06BB03 Aciclovir(C) 199734 g
D06BB04 Podophyllotoxin(C) 1253 ml
D06BB06 Penciclovir(C) 28 g
D06BB10 Imiquimod(C) 6467 g
D06BB81 Aciclovir+Hydrocortisone(C) 31168 g
D06BX Other chemotherapeutics
D06BX01 Metronidazole (C) 123150 g
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AA Corticosteroids, weak (group I)
D07AA02 Hydrocortisone(C) 590660 g
D07AC Corticosteroids, potent (group III)
D07AC01 Betamethasone(C) 139380 g
D07AC04 Fluocinolone acetonide(C) 435 g
D07AC13 Mometasone(C) 332200 ml
D07AC13 Mometasone(C) 1176620 g
D07AC14 Methylprednisolone aceponate(C) 587385 g
D07AC17 Fluticasone(C) 51435 g
D07AD Corticosteroids, very potent (group IV)
D07AD01 Clobetasol(C) 89625 ml
D07AD01 Clobetasol(C) 935100 g
D07B CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS
D07BA Corticosteroids, weak, combinations with antiseptics
D07BA80 Hydrocortisone+Chlorhexidine(C) 350700 g
D07BC Corticosteroids, potent, combinations with antiseptics
D07BC80 Betamethasone+Salicylic acid(C) 17435 g
D07BC80 Betamethasone+Salicylic acid(C) 937650 ml
D07C CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
D07CA Corticosteroids, weak, combinations with antibiotics
D07CA83 Hydrocortisone+Fusidic acid(C) 77550 g
D07CC Corticosteroids, potent, combinations with antibiotics
D07CC80 Betamethasone+Fusidic acid(C) 570150 g
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XA Corticosteroids, weak, other combinations
D07XA81 Prednisolone+Salicylic acid(C) 229500 ml
D07XC Corticosteroids, potent, other combinations
D07XC03 Mometasone+Salicylic acid(C) 225,6 g
D08 ANTISEPTICS AND DISINFECTANTS
D08A ANTISEPTICS AND DISINFECTANTS
14/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D08AG Iodine products
D08AG02 Povidone, iodinated(C) 1095050 ml
D08AG02 Povidone, iodinated(C) 3596810 g
D08AG03 Iodine(C) 921240 ml
D08AJ Quaternary ammonium compounds
D08AJ81 Octenidine+Phenoxyethanol(C) 11705950 ml
D08AX Other antiseptics and disinfectants
D08AX82 Tar+Castor oil+Xeroformium(C) 7350 g
D08AX83 Brilliant Green(C) 268060 ml
D10 ANTI-ACNE PREPARATIONS 0,5408
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AD Retinoids for topical use in acne
D10AD01 Tretinoin(C) 26850 g
D10AD03 Adapalene(C) 109650 g
D10AD80 Adapalene+Benzoyl peroxide(C) 95220 g
D10AD81 Tretinoin+Erythromycin(C) 28110 g
D10AF Antiinfectives for treatment of acne
D10AF02 Erythromycin(C) 229900 ml
D10AF81 Clindamycin+Benzoyl peroxide(C) 304875 g
D10AF82 Clindamycin+Tretinoin(C) 128820 g
D10AX Other anti-acne preparations for topical use
D10AX03 Azelaic acid(C) 317250 g
D10B ANTI-ACNE PREPARATIONS FOR SYSTEMIC USE 0,5408
D10BA Retinoids for treatment of acne 0,5408
D10BA01 Isotretinoin(O) 7868,4 g 0,03 g 0,5408
D11 OTHER DERMATOLOGICAL PREPARATIONS 0,0800
D11A OTHER DERMATOLOGICAL PREPARATIONS 0,0800
D11AH Agents for dermatitis, excluding corticosteroids 0,0184
D11AH01 Tacrolimus(C) 66390 g
D11AH02 Pimecrolimus(C) 222240 g
D11AH05 Dupilumab(P) 190,8 g 21,4 mg 0,0184
D11AX Other dermatologicals 0,0617
D11AX01 Minoxidil(C) 166680 ml
D11AX10 Finasteride(O) 29,904 g 0,001 g 0,0617
D11AX16 Eflornithine(C) 870 g
D11AX21 Brimonidine(C) 120 g
D11AX22 Ivermectin(C) 73140 g
D11AX24 Deoxycholic acid(P) 0,08 g
G GENITO URINARY SYSTEM AND SEX HORMONES 56,3570
G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS 0,8710
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL.
COMBINATIONS WITH CORTICOSTEROIDS 0,8710
G01AA Antibiotics 0,1081
G01AA01 Nystatin(O) 600000 U
G01AA10 Clindamycin(V) 5243,5 g 0,1 g 0,1081
G01AA80 Nystatin+Neomycin+Polymyxin B(V) 48 pieces
G01AC Quinoline derivatives 0,0433
G01AC05 Dequalinium(V) 419,64 g 20 mg 0,0433
G01AF Imidazole derivatives 0,7196
G01AF01 Metronidazole (V) 12554 g 0,5 g 0,0518
G01AF02 Clotrimazole(V) 27767,8 g 0,1 g 0,5726
G01AF05 Econazole(V) 4617,6 g 0,1 g 0,0952
G02 OTHER GYNECOLOGICALS 4,1361
G02A UTEROTONICS 0,0959
G02AB Ergot alkaloids 0,0020
G02AB01 Methylergometrine(P) 0,1944 g 0,2 mg 0,0020
G02AD Prostaglandins 0,0938
G02AD02 Dinoprostone(P) 0,14 g
G02AD02 Dinoprostone(V) 1,8499 g 0,5 mg 0,0076
G02AD06 Misoprostol(O) 8,3624 g 0,2 mg 0,0862
G02B CONTRACEPTIVES FOR TOPICAL USE 2,5451
15/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G02BA Intrauterine contraceptives 0,0176
G02BA03 Levonorgestrel(V) 8520 pieces 1 pieces 0,0176
G02BB Intravaginal contraceptives 2,5275
G02BB01 Etonogestrel+Ethinylestradiol(V) 42954 pieces 0,036 pieces 2,4604
G02BB81 Benzalkonium chloride(V) 32560 pieces 1 pieces 0,0671
G02BB81 Benzalkonium chloride(V) 40680 g
G02C OTHER GYNECOLOGICALS 1,4951
G02CA Sympathomimetics, labour repressants
G02CA80 Hexoprenaline(P) 0,0164 g
G02CB Prolactine inhibitors 0,1403
G02CB01 Bromocriptine(O) 276 g 0,005 g 0,1138
G02CB03 Cabergoline(O) 6,42 g 0,5 mg 0,0265
G02CX Other gynecologicals 1,3548
G02CX01 Atosiban(P) 0,5962 g 0,165 g <0,0001
G02CX03 Agni casti fructus(O) 378870 pieces 1 pieces 0,7813
G02CX04 Cimicifugae rhizoma(O) 556290 pieces 2 pieces 0,5736
G03 SEX HORMONES AND MODULATORS OF THE GENITAL
SYSTEM 30,7035
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE 24,3650
G03AA Progestogens and estrogens, fixed combinations 19,6630
G03AA07 Levonorgestrel+Ethinylestradiol(O) 205436 pieces 1 pieces 0,4236
G03AA09 Desogestrel+Ethinylestradiol(O) 423549 pieces 0,75 pieces 1,1645
G03AA10 Gestodene+Ethinylestradiol(O) 9324 pieces 1 pieces 0,0192
G03AA10 Gestodene+Ethinylestradiol(O) 2165163 pieces 0,75 pieces 5,9530
G03AA12 Drospirenone+Ethinylestradiol(O) 1203552 pieces 1 pieces 2,4818
G03AA12 Drospirenone+Ethinylestradiol(O) 1732962 pieces 0,75 pieces 4,7646
G03AA13 Norelgestromin+Ethinylestradiol(TD) 91479 pieces 0,107 pieces 1,7630
G03AA15 Chlormadinone+Ethinylestradiol(O) 155673 pieces 0,75 pieces 0,4280
G03AA16 Dienogest+Ethinylestradiol(O) 368004 pieces 1 pieces 0,7588
G03AA16 Dienogest+Ethinylestradiol(O) 693399 pieces 0,75 pieces 1,9064
G03AB Progestogens and estrogens, sequential preparations 0,1742
G03AB05 Desogestrel+Ethinylestradiol(O) 3432 pieces 0,75 pieces 0,0094
G03AB08 Dienogest+Estradiol valerate(O) 79884 pieces 1 pieces 0,1647
G03AC Progestogens 4,4487
G03AC08 Etonogestrel(P) 56,372 g 68 mcg 1,7095
G03AC09 Desogestrel(O) 1328376 pieces 1 pieces 2,7392
G03AD Emergency contraceptives 0,0792
G03AD01 Levonorgestrel(O) 56,0355 g 1,5 mg 0,0770
G03AD02 Ulipristal(O) 30,96 g 0,03 g 0,0021
G03B ANDROGENS 0,2331
G03BA 3-oxoandrosten (4) derivatives 0,2331
G03BA03 Testosterone(C) 6 g 0,05 g 0,0002
G03BA03 Testosterone(O) 14,4 g 0,12 g 0,0002
G03BA03 Testosterone(P) 2021,5 g 0,018 g 0,2316
G03BA03 Testosterone(TD) 25,76 g 0,05 g 0,0011
G03C ESTROGENS 1,4872
G03CA Natural and semisynthetic estrogens, plain 1,4772
G03CA03 Estradiol(C, V) 74225 g
G03CA03 Estradiol(O) 794,332 g 2 mg 0,8190
G03CA03 Estradiol(TD) 0,021 g 0,05 mg 0,0009
G03CA03 Estradiol(TD) 35,5572 g 1,53 mg 0,0479
G03CA03 Estradiol(TD) 75,012 g 1 mg 0,1547
G03CA03 Estradiol(V) 3,3127 g 0,025 mg 0,2732
G03CA04 Estriol(V) 17,6025 g 0,2 mg 0,1815
G03CA80 Estradiol+Prednisolone(C) 66250 g
G03CX Other estrogens 0,0100
G03CX01 Tibolone(O) 12,11 g 2,5 mg 0,0100
G03D PROGESTOGENS 1,7406
G03DA Pregnen (4) derivatives 1,0147
G03DA02 Medroxyprogesterone(O) 57,6 g 0,005 g 0,0238
G03DA02 Medroxyprogesterone(P) 250,485 g 0,007 g 0,0738
16/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G03DA04 Progesterone(O) 18807 g 0,3 g 0,1293
G03DA04 Progesterone(P) 218,7812 g 0,005 g 0,0902
G03DA04 Progesterone(V) 30450,45 g 0,09 g 0,6977
G03DB Pregnadien derivatives 0,7259
G03DB01 Dydrogesterone(O) 2592,2 g 0,01 g 0,5345
G03DB08 Dienogest(O) 185,64 g 2 mg 0,1914
G03F PROGESTOGENS AND ESTROGENS IN COMBINATION 2,1009
G03FA Progestogens and estrogens, fixed combinations 1,6631
G03FA01 Norethisterone+Estradiol(O) 512568 pieces 1 pieces 1,0570
G03FA14 Dydrogesterone+Estradiol(O) 127316 pieces 1 pieces 0,2625
G03FA17 Drospirenone+Estradiol(O) 166656 pieces 1 pieces 0,3437
G03FB Progestogens and estrogens, sequential preparations 0,4378
G03FB05 Norethisterone+Estradiol(O) 156464 pieces 1 pieces 0,3226
G03FB08 Dydrogesterone+Estradiol(O) 55832 pieces 1 pieces 0,1151
G03G GONADOTROPINS AND OTHER OVULATION STIMULANTS 0,3707
G03GA Gonadotropins 0,1481
G03GA01 Chorionic gonadotrophin(P) 45000 U 250 U 0,0004
G03GA05 Follitropin alfa(P) 4505175 U 75 U 0,1239
G03GA07 Lutropin alfa(P) 564975 U 75 U 0,0155
G03GA08 Choriogonadotropin alfa(P) 0,7398 g 0,25 mg 0,0061
G03GA30 Follitropin alfa+Lutropin alfa(P) 1075 doses 1 doses 0,0022
G03GB Ovulation stimulants, synthetic 0,2226
G03GB02 Clomifene(O) 971,5 g 0,009 g 0,2226
G03H ANTIANDROGENS 0,3996
G03HA Antiandrogens, plain 0,0810
G03HA01 Cyproterone(O) 3927,5 g 0,1 g 0,0810
G03HB Antiandrogens and estrogens 0,3187
G03HB01 Cyproterone+Estrogen(O) 115899 pieces 0,75 pieces 0,3187
G03X OTHER SEX HORMONES AND MODULATORS OF THE
GENITAL SYSTEM 0,0063
G03XA Antigonadotropins and similar agents 0,0006
G03XA01 Danazol(O) 180 g 0,6 g 0,0006
G03XB Progesterone receptor modulators 0,0057
G03XB01 Mifepristone(O) 794,4 g 0,6 g 0,0027
G03XB02 Ulipristal(O) 7,14 g 5 mg 0,0029
G04 UROLOGICALS 20,6464
G04B UROLOGICALS 3,4825
G04BC Urinary concrement solvents
G04BC81 Sodium citrate+Potassium hydrogen carbonate+Citric acid(O) 650 pieces
G04BD Drugs for urinary frequency and incontinence 1,9961
G04BD04 Oxybutynin(O) 4611,3 g 0,015 g 0,6339
G04BD06 Propiverine(O) 8,82 g 0,03 g 0,0006
G04BD07 Tolterodine(O) 481,6 g 0,004 g 0,2483
G04BD08 Solifenacin(O) 827,1 g 0,005 g 0,3411
G04BD09 Trospium chloride(O) 3661,2 g 0,04 g 0,1887
G04BD12 Mirabegron(O) 14146,5 g 50 mg 0,5834
G04BE Drugs used in erectile dysfunction 1,4762
G04BE01 Alprostadil(P) 0,0455 g 0,02 mg 0,0047
G04BE01 Alprostadil(urethral) 0,144 g 0,25 mg 0,0012
G04BE03 Sildenafil(O) 25530,8 g 0,05 g 1,0529
G04BE08 Tadalafil(O) 1726,52 g 0,01 g 0,3560
G04BE09 Vardenafil(O) 47,12 g 0,01 g 0,0097
G04BE10 Avanafil(O) 2506,8 g 0,1 g 0,0517
G04BX Other urologicals 0,0102
G04BX14 Dapoxetin(O) 147,96 g 0,03 g 0,0102
G04BX80 Centaury+Lovage root+Rosemary leaf(O) 1031520 pieces
G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY 17,1640
17/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G04CA Alpha-adrenoreceptor antagonists 14,2023
G04CA01 Alfuzosin(O) 8265,3 g 7,5 mg 2,2725
G04CA02 Tamsulosin(O) 1543,772 g 0,4 mg 7,9584
G04CA04 Silodosin(O) 747,32 g 8 mg 0,1926
G04CA52 Tamsulosin+Dutasteride(O) 1832520 pieces 1 pieces 3,7788
G04CB Testosterone-5-alpha reductase inhibitors 0,5732
G04CB01 Finasteride(O) 393,67 g 0,005 g 0,1624
G04CB02 Dutasteride(O) 99,63 g 0,5 mg 0,4109
G04CX Other drugs used in benign prostatic hypertrophy 2,3884
G04CX02 Sabalis serrulatae fructus(O) 370646,4 g 0,32 g 2,3884
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX
HORMONES AND INSULINS 30,5130
H01 PITUITARY AND HYPOTHALAMIC HORMONES AND
ANALOGUES 0,4578
H01A ANTERIOR PITUITARY LOBE HORMONES AND
ANALOGUES 0,1824
H01AA ACTH 0,0002
H01AA02 Tetracosactide(P) 0,0293 g 0,25 mg 0,0002
H01AB Thyrotropin 0,0004
H01AB01 Thyrotropin alfa(P) 0,1548 g 0,9 mg 0,0004
H01AC Somatropin and somatropin agonists 0,1621
H01AC01 Somatropin(P) 157203,9153 U 2 U 0,1621
H01AX Other anterior pituitary lobe hormones and analogues 0,0197
H01AX01 Pegvisomant(P) 95,4 g 0,01 g 0,0197
H01B POSTERIOR PITUITARY LOBE HORMONES 0,1423
H01BA Vasopressin and analogues 0,0909
H01BA01 Argipressin(P) 24000 U 40 U 0,0012
H01BA02 Desmopressin(N) 0,0306 g 0,025 mg 0,0025
H01BA02 Desmopressin(P) 0,0218 g 0,004 mg 0,0112
H01BA02 Desmopressin(SL) 8,8398 g 0,24 mg 0,0760
H01BB Oxytocin and analogues 0,0514
H01BB01 Demoxytocin(O) 970000 U 100 U 0,0200
H01BB02 Oxytocin(P) 216600 U 15 U 0,0298
H01BB03 Carbetocin(P) 0,078 g 0,1 mg 0,0016
H01C HYPOTHALAMIC HORMONES 0,1331
H01CA Gonadotropin-releasing hormones
H01CA01 Gonadorelin(P) 0,0042 g
H01CB Somatostatin and analogues 0,1142
H01CB02 Octreotide(P) 12,359 g 0,7 mg 0,0364
H01CB03 Lanreotide(P) 101,19 g 3 mg 0,0696
H01CB05 Pasireotide(P) 4,79 g 1,2 mg 0,0082
H01CC Anti-gonadotropin-releasing hormones 0,0189
H01CC02 Cetrorelix(P) 2,2953 g 0,25 mg 0,0189
H02 CORTICOSTEROIDS FOR SYSTEMIC USE 8,9526
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN 8,9476
H02AA Mineralocorticoids 0,1683
H02AA02 Fludrocortisone(O) 8,16 g 0,1 mg 0,1683
H02AB Glucocorticoids 8,7794
H02AB01 Betamethasone(P) 13,968 g 1,5 mg 0,0192
H02AB02 Dexamethasone(O) 852,84 g 1,5 mg 1,1724
H02AB02 Dexamethasone(P) 1039,8 g 1,5 mg 1,4294
H02AB04 Methylprednisolone(O) 7298,8 g 7,5 mg 2,0067
H02AB04 Methylprednisolone(P) 4466,85 g 0,02 g 0,4605
H02AB06 Prednisolone(O) 12583 g 0,01 g 2,5947
H02AB06 Prednisolone(P) 2013,65 g 0,01 g 0,4152
H02AB08 Triamcinolone(O) 10 g 7,5 mg 0,0027
H02AB08 Triamcinolone(P) 1447,6 g 7,5 mg 0,3980
H02AB09 Hydrocortisone(O) 3493,05 g 0,03 g 0,2401
H02AB09 Hydrocortisone(P) 585,8 g 0,03 g 0,0403
H02B CORTICOSTEROIDS FOR SYSTEMIC USE, COMBINATIONS 0,0050
18/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
H02BX Corticosteroids for systemic use, combinations 0,0050
H02BX80 Hydrocortisone+Lidocaine(P) 72,125 g 0,03 g 0,0050
H03 THYROID THERAPY 21,0621
H03A THYROID PREPARATIONS 19,9294
H03AA Thyroid hormones 19,9294
H03AA01 Levothyroxine sodium(O) 1449,575 g 0,15 mg 19,9275
H03AA02 Liothyronine(O) 0,0553 g 0,06 mg 0,0019
H03AA03 Levothyroxine sodium+Liothyronine(O) 500 pieces
H03B ANTITHYROID PREPARATIONS 1,1327
H03BA Thiouracils 0,0920
H03BA02 Propylthiouracil(O) 4463,5 g 0,1 g 0,0920
H03BB Sulfur-containing imidazole derivatives 1,0407
H03BB02 Thiamazole(O) 5046,75 g 0,01 g 1,0407
H03BC Perchlorates
H03BC02 Sodium perchlorate(O) 48 g
H04 PANCREATIC HORMONES 0,0011
H04A GLYCOGENOLYTIC HORMONES 0,0011
H04AA Glycogenolytic hormones 0,0011
H04AA01 Glucagon(P) 0,54 g 0,001 g 0,0011
H05 CALCIUM HOMEOSTASIS 0,0393
H05B ANTI-PARATHYROID AGENTS 0,0393
H05BX Other anti-parathyroid agents 0,0393
H05BX01 Cinacalcet(O) 931,56 g 0,06 g 0,0320
H05BX02 Paricalcitol(O) 0,0071 g 2 mcg 0,0073
J ANTIINFECTIVES FOR SYSTEMIC USE 17,7152
J01 ANTIBACTERIALS FOR SYSTEMIC USE 10,6478
J01A TETRACYCLINES 1,3901
J01AA Tetracyclines 1,3901
J01AA02 Doxycycline(O) 67380,24 g 0,1 g 1,3894
J01AA07 Tetracycline(O) 7 g 1 g <0,0001
J01AA12 Tigecycline(P) 31 g 0,1 g 0,0006
J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS 3,7574
J01CA Penicillins with extended spectrum 1,3216
J01CA01 Ampicillin(P) 20900 g 6 g 0,0072
J01CA04 Amoxicillin(O) 956108 g 1,5 g 1,3144
J01CA04 Amoxicillin(P) 10 g 3 g <0,0001
J01CE Beta-lactamase sensitive penicillins 0,1220
J01CE01 Benzylpenicillin(P) 27540 g 3,6 g 0,0158
J01CE02 Phenoxymethylpenicillin(O) 102289,2 g 2 g 0,1055
J01CE08 Benzathine benzylpenicillin(P) 1337,4 g 3,6 g 0,0008
J01CE80 Benzathine benzylpenicillin+Procaine benzylpenicillin(P) 15,3 g 3,6 g <0,0001
J01CF Beta-lactamase resistant penicillins 0,0978
J01CF04 Oxacillin(P) 94584 g 2 g 0,0975
J01CF05 Flucloxacillin(O) 240 g 2 g 0,0002
J01CR Combinations of penicillins, incl. beta-lactamase inhibitors 2,2161
J01CR01 Ampicillin+Sulbactam(P) 70434 g 6 g 0,0242
J01CR02 Amoxicillin+Clavulanic acid(O) 1352010,1 g 1,5 g 1,8586
J01CR02 Amoxicillin+Clavulanic acid(P) 306478 g 3 g 0,2107
J01CR04 Sultamicillin(O) 50013 g 1,5 g 0,0688
J01CR05 Piperacillin+Tazobactam(P) 365628 g 14 g 0,0539
J01D OTHER BETA-LACTAM ANTIBACTERIALS 1,5344
J01DB First-generation cephalosporins 0,2135
J01DB01 Cefalexin(O) 96 g 2 g 0,0001
J01DB04 Cefazolin(P) 109130 g 3 g 0,0750
J01DB05 Cefadroxil(O) 134219 g 2 g 0,1384
J01DC Second-generation cephalosporins 1,1693
J01DC01 Cefoxitin(P) 13850 g 6 g 0,0048
J01DC02 Cefuroxime(O) 229047,5 g 0,5 g 0,9446
J01DC02 Cefuroxime(P) 263572,5 g 3 g 0,1812
J01DC10 Cefprozil(O) 18805,5 g 1 g 0,0388
19/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J01DD Third-generation cephalosporins 0,0590
J01DD01 Cefotaxime(P) 50730 g 4 g 0,0262
J01DD02 Ceftazidime(P) 17860 g 4 g 0,0092
J01DD04 Ceftriaxone(P) 21570 g 2 g 0,0222
J01DD81 Ceftazidime+Avibactam(P) 3980 g 6 g 0,0014
J01DE Fourth-generation cephalosporins 0,0143
J01DE01 Cefepime(P) 27710 g 4 g 0,0143
J01DH Carbapenems 0,0782
J01DH02 Meropenem(P) 57741 g 3 g 0,0397
J01DH03 Ertapenem(P) 11652 g 1 g 0,0240
J01DH51 Imipenem+Cilastatin(P) 14055 g 2 g 0,0145
J01DI Other cephalosporins and penems 0,0002
J01DI54 Ceftolozane+Tazobactam(P) 240 g 3 g 0,0002
J01E SULFONAMIDES AND TRIMETHOPRIM 0,3386
J01EA Trimethoprim and derivatives 0,0418
J01EA01 Trimethoprim(O) 8106 g 0,4 g 0,0418
J01EE Combinations of sulfonamides and trimethoprim, incl.
derivatives 0,2968
J01EE01 Sulfamethoxazole+Trimethoprim(O) 248400 pieces 2 pieces 0,2561
J01EE01 Sulfamethoxazole+Trimethoprim(O) 674100 ml 40 ml 0,0348
J01EE01 Sulfamethoxazole+Trimethoprim(P) 57530 ml 20 ml 0,0059
J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS 1,9702
J01FA Macrolides 1,8016
J01FA01 Erythromycin(P) 400 g 1 g 0,0008
J01FA09 Clarithromycin(O) 309700 g 0,5 g 1,2772
J01FA09 Clarithromycin(P) 3356 g 1 g 0,0069
J01FA10 Azithromycin(O) 75143,5 g 0,3 g 0,5165
J01FA10 Azithromycin(P) 17,5 g 0,5 g 0,0001
J01FF Lincosamides 0,1686
J01FF01 Clindamycin(O) 90580,8 g 1,2 g 0,1557
J01FF01 Clindamycin(P) 11316 g 1,8 g 0,0130
J01G AMINOGLYCOSIDE ANTIBACTERIALS 0,0240
J01GB Other aminoglycosides 0,0240
J01GB01 Tobramycin(I) 50,176 g 0,112 g 0,0009
J01GB01 Tobramycin(I) 268,8 g 0,3 g 0,0018
J01GB01 Tobramycin(P) 48 g 0,24 g 0,0004
J01GB03 Gentamicin(P) 1439,2 g 0,24 g 0,0124
J01GB04 Kanamycin(P) 500 g 1 g 0,0010
J01GB06 Amikacin(P) 3610 g 1 g 0,0074
J01M QUINOLONE ANTIBACTERIALS 0,8827
J01MA Fluoroquinolones 0,8827
J01MA01 Ofloxacin(O) 3198 g 0,4 g 0,0165
J01MA02 Ciprofloxacin(O) 287275 g 1 g 0,5924
J01MA02 Ciprofloxacin(P) 12342,5 g 0,8 g 0,0318
J01MA06 Norfloxacin(O) 59584 g 0,8 g 0,1536
J01MA12 Levofloxacin(O) 8718,5 g 0,5 g 0,0360
J01MA12 Levofloxacin(P) 475 g 0,5 g 0,0020
J01MA14 Moxifloxacin(O) 9532 g 0,4 g 0,0491
J01MA14 Moxifloxacin(P) 263,6 g 0,4 g 0,0014
J01X OTHER ANTIBACTERIALS 0,7504
J01XA Glycopeptide antibacterials 0,0248
J01XA01 Vancomycin(O) 12 g 2 g <0,0001
J01XA01 Vancomycin(P) 23935 g 2 g 0,0247
J01XA02 Teicoplanin(P) 12 g 0,4 g 0,0001
J01XB Polymyxins 0,0020
J01XB01 Colistin(I, P) 1170000000 U 9000000 U 0,0003
J01XB01 Colistin(P) 7650000000 U 9000000 U 0,0018
J01XD Imidazole derivatives 0,2291
J01XD01 Metronidazole (O) 181715 g 2 g 0,1874
J01XD01 Metronidazole (P) 30350 g 1,5 g 0,0417
20/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J01XE Nitrofuran derivatives 0,4697
J01XE01 Nitrofurantoin(O) 45552,5 g 0,2 g 0,4697
J01XX Other antibacterials 0,0249
J01XX01 Fosfomycin(O) 13338 g 3 g 0,0092
J01XX08 Linezolid(O) 7008 g 1,2 g 0,0120
J01XX08 Linezolid(P) 1404 g 1,2 g 0,0024
J01XX09 Daptomycin(P) 172,4 g 0,28 g 0,0013
J02 ANTIMYCOTICS FOR SYSTEMIC USE 0,3909
J02A ANTIMYCOTICS FOR SYSTEMIC USE 0,3909
J02AA Antibiotics 0,0096
J02AA01 Amphotericin(O) 234 g
J02AA01 Amphotericin(P) 162,75 g 0,035 g 0,0096
J02AC Triazole derivatives 0,3704
J02AC01 Fluconazole(O) 13979,95 g 0,2 g 0,1441
J02AC01 Fluconazole(P) 3298,6 g 0,2 g 0,0340
J02AC02 Itraconazole(O) 15481 g 0,2 g 0,1596
J02AC03 Voriconazole(O) 2014,8 g 0,4 g 0,0104
J02AC03 Voriconazole(P) 129 g 0,4 g 0,0007
J02AC04 Posaconazole(O) 3100,8 g 0,3 g 0,0213
J02AC05 Isavuconazole(O) 26,6 g 0,2 g 0,0003
J02AC05 Isavuconazole(P) 3,2 g 0,2 g <0,0001
J02AX Other antimycotics for systemic use 0,0109
J02AX04 Caspofungin(P) 103,27 g 0,05 g 0,0043
J02AX06 Anidulafungin(P) 322,6 g 0,1 g 0,0067
J04 ANTIMYCOBACTERIALS 0,2924
J04A DRUGS FOR TREATMENT OF TUBERCULOSIS 0,2631
J04AA Aminosalicylic acid and derivatives 0,0005
J04AA01 Paraaminosalicylic acid(O) 3000 g 12 g 0,0005
J04AB Antibiotics 0,0569
J04AB01 Cycloserine(O) 6000 g 0,75 g 0,0165
J04AB02 Rifampicin(O) 11685,6 g 0,6 g 0,0402
J04AB02 Rifampicin(P) 60 g 0,6 g 0,0002
J04AK Other drugs for treatment of tuberculosis 0,1665
J04AK01 Pyrazinamide(O) 30000 g 1,5 g 0,0412
J04AK02 Ethambutol(O) 67400 g 1,2 g 0,1158
J04AK05 Bedaquiline(O) 394,8 g 86 mg 0,0095
J04AM Combinations of drugs for treatment of tuberculosis 0,0392
J04AM02 Rifampicin+Isoniazid(O) 8000 pieces 4 pieces 0,0041
J04AM02 Rifampicin+Isoniazid(O) 34000 pieces 2 pieces 0,0351
J04B DRUGS FOR TREATMENT OF LEPRA 0,0293
J04BA Drugs for treatment of lepra 0,0293
J04BA01 Clofazimine(O) 800 g 0,1 g 0,0165
J04BA02 Dapsone(O) 310 g 0,05 g 0,0128
J05 ANTIVIRALS FOR SYSTEMIC USE 6,3840
J05A DIRECT ACTING ANTIVIRALS 6,3840
J05AB Nucleosides and nucleotides excl. reverse transcriptase
inhibitors 0,4043
J05AB01 Aciclovir(O) 392911,5 g 4 g 0,2026
J05AB01 Aciclovir(P) 3823,75 g 4 g 0,0020
J05AB06 Ganciclovir(P) 375,5 g 0,5 g 0,0015
J05AB09 Famciclovir(O) 168 g 0,75 g 0,0005
J05AB11 Valaciclovir(O) 268834 g 3 g 0,1848
J05AB12 Cidofovir(P) 1,5 g 0,025 g 0,0001
J05AB14 Valganciclovir(O) 5619 g 0,9 g 0,0129
J05AB80 Remdesivir(P) 163,4 g
J05AE Protease inhibitors 0,3255
J05AE03 Ritonavir(O) 21048 g 1,2 g 0,0362
J05AE10 Darunavir(O) 168384 g 1,2 g 0,2893
J05AF Nucleoside and nucleotide reverse transcriptase inhibitors 0,1236
J05AF01 Zidovudine(O) 198 g 0,6 g 0,0007
21/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J05AF01 Zidovudine(P) 39 g 0,6 g 0,0001
J05AF05 Lamivudine(O) 1821 g 0,3 g 0,0125
J05AF06 Abacavir(O) 1755,6 g 0,6 g 0,0060
J05AF07 Tenofovir disoproxil(O) 235,2 g 0,245 g 0,0020
J05AF10 Entecavir(O) 23,805 g 0,5 mg 0,0982
J05AF13 Tenofovir alafenamide(O) 49,5 g 25 mg 0,0041
J05AG Non-nucleoside reverse transcriptase inhibitors 0,8082
J05AG03 Efavirenz(O) 43560 g 0,6 g 0,1497
J05AG05 Rilpivirine(O) 7983,75 g 25 mg 0,6585
J05AH Neuraminidase inhibitors 0,1187
J05AH02 Oseltamivir(O) 8637,75 g 0,15 g 0,1187
J05AJ Integrase inhibitors 0,9169
J05AJ01 Raltegravir(O) 324120 g 0,8 g 0,8354
J05AJ03 Dolutegravir(O) 1974,75 g 50 mg 0,0814
J05AP Antivirals for treatment of HCV infections 0,0955
J05AP01 Ribavirin(O) 392 g 1 g 0,0008
J05AP54 Elbasvir+Grazoprevir(O) 1540 pieces 1 pieces 0,0032
J05AP55 Sofosbuvir+Velpatasvir(O) 5460 pieces 1 pieces 0,0113
J05AP57 Glecaprevir+Pibrentasvir(O) 116760 pieces 3 pieces 0,0803
J05AR Antivirals for treatment of HIV infections, combinations 3,5780
J05AR01 Zidovudine+Lamivudine(O) 40380 pieces 2 pieces 0,0416
J05AR02 Lamivudine+Abacavir(O) 332850 pieces 1 pieces 0,6864
J05AR03 Tenofovir disoproxil+Emtricitabine(O) 841590 pieces 1 pieces 1,7354
J05AR06 Emtricitabine+Tenofovir disoproxil+Efavirenz(O) 33720 pieces 1 pieces 0,0695
J05AR10 Lopinavir+Ritonavir(O) 168 g 0,8 g 0,0004
J05AR13 Lamivudine+Abacavir+Dolutegravir(O) 287040 pieces 1 pieces 0,5919
J05AR14 Darunavir+Cobicistat(O) 219180 pieces 1 pieces 0,4520
J05AR18 Emtricitabine+Tenofovir
alafenamide+Elvitegravir+Cobicistat(O) 360 pieces 1 pieces 0,0007
J05AX Other antivirals 0,0133
J05AX27 Favipiravir(O) 10296 g 1,6 g 0,0133
J06 IMMUNE SERA AND IMMUNOGLOBULINS
J06A IMMUNE SERA
J06AA Immune sera
J06AA01 Diphtheria antitoxin(P) 200000 U
J06AA03 Snake venom antiserum(P) 70 pieces
J06B IMMUNOGLOBULINS
J06BA Immunoglobulins, normal human
J06BA01 Immunoglobulins, normal human, for extravascular a(P) 12919,5 g
J06BA02 Immunoglobulins, normal human, for intravascular a(P) 110590 g
J06BB Specific immunoglobulins
J06BB01 Human Anti-D Immunoglobulin(P) 1947125 U
J06BB02 Tetanus immunoglobulin(P) 12000 U
J06BB03 Varicella zoster immunoglobulin(P) 2500 U
J06BB04 Hepatitis B immunoglobulin(P) 2800 U
J06BB05 Rabies immunoglobulin(P) 3000 U
J06BB16 Palivizumab(P) 44,1 g
J07 VACCINES
J07A BACTERIAL VACCINES
J07AG Hemophilus influenzae B vaccines
J07AG01 Haemophilus influenzae B, purified antigen conjugated(P) 373 doses
J07AH Meningococcal vaccines
J07AH08 Meningococcus, tetravalent purified polysaccharides antigen
conjugated(P) 507 doses
J07AH09 Meningococcus B, multicomponent vaccine(P) 42 doses
J07AL Pneumococcal vaccines
J07AL01 Pneumococcus, purified polysaccharides antigen(P) 1110 doses
J07AL02 Pneumococcus, purified polysaccharides antigen
conjugated(P) 4838 doses
22/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J07AL52 Pneumococcus, purified polysaccharides antigen+Haemophilus
influenzae, conjugated(P) 228 doses
J07AM Tetanus vaccines
J07AM51 Tetanus toxoid+Diphtheria toxoid(P) 23175 doses
J07AN Tuberculosis vaccines
J07AN01 Tuberculosis, live attenuated(P) 23260 doses
J07AP Typhoid vaccines
J07AP03 Typhoid, purified polysaccharide antigen(P) 825 doses
J07AX Other bacterial vaccines
J07AX80 Diphtheria-tetanus-pertussis(P) 17482 doses
J07B VIRAL VACCINES
J07BA Encephalitis vaccines
J07BA01 Encephalitis, tick borne, inactivated, whole virus(P) 88374 doses
J07BB Influenza vaccines
J07BB02 Influenza, inactivated, split virus or surface antigen(P) 153821 doses
J07BC Hepatitis vaccines
J07BC01 Hepatitis B, purified antigen(P) 3303 doses
J07BC02 Hepatitis A, inactivated, whole virus(P) 4308 doses
J07BC80 Hepatitis A, inactivated, whole virus+Hepatitis B, purified
antigen(P) 1625 doses
J07BD Measles vaccines
J07BD52 Measles, live attunated+Rubella, live attenuated+Mumps,
live,attenuated(P) 31091 doses
J07BF Poliomyelitis vaccines
J07BF03 Poliomyelitis, trivalent, inactivated, whole virus(P) 607 doses
J07BG Rabies vaccines
J07BG01 Rabies, inactivated, whole virus(P) 1774 doses
J07BH Rota virus diarrhea vaccines
J07BH02 Rota virus, pentavalent, live, reassorted(O) 64411 doses
J07BK Varicella zoster vaccines
J07BK01 Varicella, live attenuated(P) 2096 doses
J07BK02 Zoster, live attenuated(P) 40 doses
J07BK03 Zoster, purified antigen(P) 5 doses
J07BL Yellow fever vaccines
J07BL01 Yellow fever, live attenuated(P) 773 doses
J07BM Papillomavirus vaccines
J07BM02 Papillomavirus (human types 16, 18)(P) 9 doses
J07BM03 Papillomavirus (human types 6, 11, 16, 18, 31, 33, 45, 52,
58)(P) 12056 doses
J07BX Other viral vaccines
J07BX03 Covid-19 vaccine(P) 6099,6 doses
J07C BACTERIAL AND VIRAL VACCINES, COMBINED
J07CA Bacterial and viral vaccines, combined
J07CA02 Diphtheria toxoid+Pertussis, purified antigen+Tetanus
toxoid+Poliomyelitis, trivalent, inactivated, whole virus(P) 15054 doses
J07CA06
Diphtheria toxoid+Tetanus toxoid+Pertussis, purified
antigen+Poliomyelitis, trivalent, inactivated, whole
virus+Haemophilus influenzae B, purified antigen
conjugated(P)
1049 doses
J07CA09
Diphtheria toxoid+Poliomyelitis, trivalent, inactivated, whole
virus+Pertussis, purified antigen+Haemophilus influenzae B,
purified antigen conjugated+Hepatitis B, purified
antigen+Tetanus toxoid(P)
48420 doses
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS 12,4653
L01 ANTINEOPLASTIC AGENTS
L01A ALKYLATING AGENTS
L01AA Nitrogen mustard analogues
L01AA01 Cyclophosphamide(O) 627,5 g
L01AA01 Cyclophosphamide(P) 3931 g
L01AA02 Chlorambucil(O) 22,9 g
L01AA03 Melphalan(O) 4,7 g
23/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01AA03 Melphalan(P) 26,1 g
L01AA06 Ifosfamide(P) 1640 g
L01AA09 Bendamustine(P) 121 g
L01AB Alkyl sulfonates
L01AB01 Busulfan(O) 7 g
L01AB01 Busulfan(P) 4,32 g
L01AB02 Treosulfan(P) 1375 g
L01AC Ethylene imines
L01AC01 Thiotepa(P) 6,805 g
L01AD Nitrosoureas
L01AD01 Carmustine(P) 13,8 g
L01AD02 Lomustine(O) 16,4 g
L01AX Other alkylating agents
L01AX03 Temozolomide(O) 609,35 g
L01AX04 Dacarbazine(P) 395 g
L01B ANTIMETABOLITES
L01BA Folic acid analogues
L01BA01 Methotrexate(P) 1624,1 g
L01BA04 Pemetrexed(P) 431 g
L01BB Purine analogues
L01BB02 Mercaptopurine(O) 417,5 g
L01BB03 Tioguanine(O) 9 g
L01BB04 Cladribine(P) 0,34 g
L01BB05 Fludarabine(P) 17,85 g
L01BB07 Nelarabine(P) 4,5 g
L01BC Pyrimidine analogues
L01BC01 Cytarabine(P) 2458 g
L01BC02 Fluorouracil(P) 14785 g
L01BC05 Gemcitabine(P) 5450,3596 g
L01BC06 Capecitabine(O) 252768 g
L01BC07 Azacitidine(P) 283,7 g
L01BC83 Trifluridine+Tipiracil(O) 17480 pieces
L01C PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS
L01CA Vinca alkaloids and analogues
L01CA01 Vinblastine(P) 5,52 g
L01CA02 Vincristine(P) 2,221 g
L01CA04 Vinorelbine(O) 2,2 g
L01CA04 Vinorelbine(P) 14,6 g
L01CB Podophyllotoxin derivatives
L01CB01 Etoposide(O) 341 g
L01CB01 Etoposide(P) 502,3 g
L01CD Taxanes
L01CD01 Paclitaxel(P) 777,7 g
L01CD02 Docetaxel(P) 412 g
L01CD04 Cabazitaxel(P) 5,7 g
L01CE Topoisomerase 1 (TOP1) inhibitors
L01CE01 Topotecan(P) 3,521 g
L01CE02 Irinotecan(P) 681 g
L01D CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
L01DA Actinomycines
L01DA01 Dactinomycin(P) 0,015 g
L01DB Anthracyclines and related substances
L01DB01 Doxorubicin(P) 136,39 g
L01DB02 Daunorubicin(P) 11,28 g
L01DB03 Epirubicin(P) 187,5 g
L01DB06 Idarubicin(P) 2,16 g
L01DB07 Mitoxantrone(P) 1,88 g
L01DB11 Pixantrone(P) 1,015 g
L01DC Other cytotoxic antibiotics
24/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01DC01 Bleomycin(P) 9795000 U
L01DC03 Mitomycin(P) 5,76 g
L01E PROTEIN KINASE INHIBITORS
L01EA BCR-ABL tyrosine kinase inhibitors
L01EA01 Imatinib(O) 16512 g
L01EA02 Dasatinib(O) 648 g
L01EA03 Nilotinib(O) 8624 g
L01EA04 Bosutinib(O) 252 g
L01EA05 Ponatinib(O) 8,1 g
L01EB Epidermal growth factor receptor (EGFR) tyrosine kinase
inhibitors
L01EB01 Gefitinib(O) 1005 g
L01EB02 Erlotinib(O) 117 g
L01EB03 Afatinib(O) 129,64 g
L01EB04 Osimertinib(O) 210 g
L01EC B-Raf serine-threonine kinase (BRAF) inhibitors
L01EC02 Dabrafenib(O) 3672 g
L01ED Anaplastic lymphoma kinase (ALK) inhibitors
L01ED01 Crizotinib(O) 345 g
L01ED02 Ceritinib(O) 270 g
L01ED04 Brigatinib(O) 90,72 g
L01EE Mitogen-activated protein kinase (MEK) inhibitors
L01EE01 Trametinib(O) 25,86 g
L01EF Cyclin-dependent kinase (CDK) inhibitors
L01EF01 Palbociclib(O) 1096,2 g
L01EF02 Ribociclib(O) 3376,8 g
L01EG Mammalian target of rapamycin (mTOR) kinase inhibitors
L01EG01 Temsirolimus(P) 0,81 g
L01EG02 Everolimus(O) 43,2 g
L01EH Human epidermal growth factor receptor 2 (HER2) tyrosine
kinase inhibitors
L01EH01 Lapatinib(O) 52,5 g
L01EJ Janus-associated kinase (JAK) inhibitors
L01EJ01 Ruxolitinib(O) 254,8 g
L01EK Vascular endothelial growth factor receptor (VEGFR) tyrosine
kinase inhibitors
L01EK01 Axitinib(O) 28 g
L01EL Bruton's tyrosine kinase (BTK) inhibitors
L01EL01 Ibrutinib(O) 9151,8 g
L01EX Other protein kinase inhibitors
L01EX01 Sunitinib(O) 288,4 g
L01EX02 Sorafenib(O) 4368 g
L01EX03 Pazopanib(O) 13824 g
L01EX05 regorafenib(O) 235,2 g
L01EX07 Cabozantinib(O) 442,96 g
L01EX08 Lenvatinib(O) 1,74 g
L01EX09 Nintedanib(O) 5871 g
L01EX10 Midostaurin(O) 60,2 g
L01X OTHER ANTINEOPLASTIC AGENTS
L01XA Platinum compounds
L01XA01 Cisplatin(P) 189,8 g
L01XA02 Carboplatin(P) 1883,4 g
L01XA03 Oxaliplatin(P) 887,4 g
L01XB Methylhydrazines
L01XB01 Procarbazine(O) 187,5 g
L01XC Monoclonal antibodies
L01XC02 Rituximab(P) 2147,96 g
L01XC03 Trastuzumab(P) 1734,15 g
L01XC06 Cetuximab(P) 109,2 g
L01XC07 Bevacizumab(P) 1178,2 g
25/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01XC08 Panitumumab(P) 108,6 g
L01XC11 Ipilimumab(P) 1,95 g
L01XC12 Brentuximab vedotin(P) 11,5 g
L01XC13 Pertuzumab(P) 308,7 g
L01XC14 Trastuzumab emtansine(P) 76,68 g
L01XC15 Obinutuzumab(P) 135 g
L01XC17 Nivolumab(P) 212,34 g
L01XC18 Pembrolizumab(P) 328,6 g
L01XC19 Blinatumomab(P) 0,0026 g
L01XC21 Ramucirumab(P) 4 g
L01XC24 Daratumumab(P) 467,6 g
L01XC26 Inotuzumab ozogamicin(P) 0,003 g
L01XC28 Durvalumab(P) 364,68 g
L01XC32 Atezolizumab(P) 289,2 g
L01XC80 Dinutuximab beta(P) 0,405 g
L01XD Sensitizers used in photodynamic/radiation therapy
L01XD04 Aminolevulinic acid(O) 7,5 g
L01XF Retinoids for cancer treatment
L01XF01 Tretinoin(O) 42 g
L01XG Proteasome inhibitors
L01XG01 Bortezomib(P) 8,897 g
L01XG02 Carfilzomib(P) 2,64 g
L01XG03 Ixazomib(O) 0,18 g
L01XK Poly (ADP-ribose) polymerase (PARP) inhibitors
L01XK01 Olaparib(O) 9260,8 g
L01XX Other antineoplastic agents
L01XX02 Asparaginase(P) 1100000 U
L01XX05 Hydroxycarbamide(O) 255250 g
L01XX11 Estramustine(O) 123,2 g
L01XX23 Mitotane(O) 950 g
L01XX24 Pegaspargase(P) 390000 U
L01XX27 Arsenic trioxide(P) 3,5 g
L01XX35 Anagrelide(O) 1,15 g
L01XX41 Eribulin(P) 0,095 g
L01XX52 Venetoclax(O) 1367,87 g
L02 ENDOCRINE THERAPY 4,7298
L02A HORMONES AND RELATED AGENTS 0,6680
L02AB Progestogens 0,0085
L02AB02 Medroxyprogesterone(O) 4110 g 1 g 0,0085
L02AE Gonadotropin releasing hormone analogues 0,6595
L02AE03 Goserelin(P) 9,5832 g 0,129 mg 0,1532
L02AE04 Triptorelin(P) 0,2429 g 0,1 mg 0,0050
L02AE04 Triptorelin(P) 32,5762 g 0,134 mg 0,5013
L02B HORMONE ANTAGONISTS AND RELATED AGENTS 4,0619
L02BA Anti-estrogens 0,8118
L02BA01 Tamoxifen(O) 6229,2 g 0,02 g 0,6423
L02BA03 Fulvestrant(P) 682,5 g 8,3 mg 0,1696
L02BB Anti-androgens 1,2948
L02BB03 Bicalutamide(O) 30907,8 g 0,05 g 1,2747
L02BB04 enzalutamide
(O) 1379,84 g 0,16 g 0,0178
L02BB05 Apalutamide(O) 273,6 g 0,24 g 0,0024
L02BG Aromatase inhibitors 1,8432
L02BG03 Anastrozole(O) 334,908 g 1 mg 0,6906
L02BG04 Letrozole(O) 1252,95 g 2,5 mg 1,0335
L02BG06 Exemestane(O) 1443,75 g 0,025 g 0,1191
L02BX Other hormone antagonists and related agents 0,1121
L02BX03 Abiraterone(O) 54360 g 1 g 0,1121
L03 IMMUNOSTIMULANTS 0,6028
L03A IMMUNOSTIMULANTS 0,6028
L03AA Colony stimulating factors 0,0904
26/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L03AA02 Filgrastim(P) 9,5856 g 0,35 mg 0,0565
L03AA13 Pegfilgrastim(P) 4,932 g 0,3 mg 0,0339
L03AB Interferons 0,3958
L03AB04 Interferon alfa-2a(P) 19131000000 U 2000000 U 0,0197
L03AB07 Interferon beta-1a(P) 0,5849 g 0,0043 mg 0,2805
L03AB08 Interferon beta-1b(P) 99720000000 U 4000000 U 0,0514
L03AB11 Peginterferon alfa-2a(P) 0,0111 g 0,026 mg 0,0009
L03AB13 Peginterferon beta-1a(P) 0,1868 g 8,9 mcg 0,0433
L03AX Other immunostimulants 0,1166
L03AX03 BCG bacteria(P) 2,8375 g 1,8 mg 0,0033
L03AX13 Glatiramer acetate(P) 1099,12 g 0,02 g 0,1133
L03AX16 Plerixafor(P) 0,528 g 16,8 mg 0,0001
L03AX80 Methyluracil(R) 240 g
L04 IMMUNOSUPPRESSANTS 7,1326
L04A IMMUNOSUPPRESSANTS 7,1326
L04AA Selective immunosuppressants 1,1772
L04AA03 Antilymphocyte immunoglobulin (horse)(P) 35 g
L04AA04 Rabbit anti-T-lymphocyte immunoglobulin(P) 19,525 g 0,1 g 0,0004
L04AA06 Mycophenolic acid(O) 309567,4 g 2 g 0,3192
L04AA06 Mycophenolic acid(P) 324 g 2 g 0,0003
L04AA10 Sirolimus(O) 22,56 g 0,003 g 0,0155
L04AA13 Leflunomide(O) 5352,9 g 0,02 g 0,5519
L04AA18 Everolimus(O) 0,36 g 1,5 mg 0,0005
L04AA23 Natalizumab(P) 47,4 g 0,01 g 0,0098
L04AA24 Abatacept(P) 174 g 0,027 g 0,0133
L04AA25 Eculizumab(P) 84,3 g 0,064 g 0,0027
L04AA26 Belimumab(P) 9,2 g 25 mg 0,0008
L04AA27 Fingolimod(O) 5,11 g 0,5 mg 0,0211
L04AA29 Tofacitinib
(O) 98 g 10 mg 0,0202
L04AA31 Teriflunomide(O) 685,608 g 14 mg 0,1010
L04AA32 Apremilast(O) 4,05 g 60 mg 0,0001
L04AA33 Vedolizumab(P) 103,5 g 5,4 mg 0,0395
L04AA34 Alemtuzumab(P) 0,252 g 0,13 mg 0,0040
L04AA36 Ocrelizumab(P) 104,1 g 3,29 mg 0,0652
L04AA40 Cladribine(O) 1,92 g 0,34 mg 0,0116
L04AA42 Siponimod(O) 0,56 g
L04AA44 Upadacitinib(O) 63,84 g
L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors 1,3593
L04AB01 Etanercept(P) 896,88 g 0,007 g 0,2642
L04AB02 Infliximab(P) 984 g 3,75 mg 0,5411
L04AB04 Adalimumab(P) 642,8 g 2,9 mg 0,4571
L04AB05 Certolizumab pegol(P) 28,8 g 14 mg 0,0042
L04AB06 Golimumab(P) 74,6 g 1,66 mg 0,0927
L04AC Interleukin inhibitors 0,4357
L04AC02 Basiliximab(P) 1,42 g 0,04 g 0,0001
L04AC03 Anakinra(P) 176,5785 g 0,1 g 0,0036
L04AC05 Ustekinumab(P) 54,515 g 0,54 mg 0,2082
L04AC07 Tocilizumab(P) 927,776 g 0,02 g 0,0957
L04AC10 Secukinumab(P) 439,2 g 10 mg 0,0906
L04AC13 Ixekizumab(P) 17,52 g 2,9 mg 0,0125
L04AC14 Sarilumab(P) 103,4 g 14,3 mg 0,0149
L04AC16 Guselkumab(P) 4,2 g 1,79 mg 0,0048
L04AC18 Risankizumab(P) 4,35 g 1,67 mg 0,0054
L04AD Calcineurin inhibitors 0,5308
L04AD01 Ciclosporin(O) 26086,25 g 0,25 g 0,2152
L04AD01 Ciclosporin(P) 85 g 0,25 g 0,0007
L04AD02 Tacrolimus(O) 763,5125 g 5 mg 0,3149
L04AD02 Tacrolimus(P) 0,2 g 5 mg 0,0001
L04AX Other immunosuppressants 3,6297
L04AX01 Azathioprine(O) 29045 g 0,15 g 0,3993
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Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L04AX02 Thalidomide(O) 434 g 0,1 g 0,0089
L04AX03 Methotrexate(O) 3437,5 g 2,5 mg 2,8353
L04AX03 Methotrexate(P) 129,835 g 2,5 mg 0,1071
L04AX04 Lenalidomide(O) 380,205 g 0,01 g 0,0784
L04AX05 Pirfenidone(O) 25837,056 g 2,4 g 0,0222
L04AX06 Pomalidomide
(O) 17,556 g 3 mg 0,0121
L04AX07 Dimethyl fumarate(O) 38718,96 g 0,48 g 0,1663
M MUSCULO-SKELETAL SYSTEM 84,4914
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS 69,3257
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS,
NON-STEROIDS 69,3145
M01AB Acetic acid derivatives and related substances 8,9249
M01AB01 Indometacin(O) 3565,5 g 0,1 g 0,0735
M01AB05 Diclofenac(O) 326928,5 g 0,1 g 6,7415
M01AB05 Diclofenac(P) 8213,625 g 0,1 g 0,1694
M01AB05 Diclofenac(R) 13236,875 g 0,1 g 0,2730
M01AB16 Aceclofenac(O) 41698 g 0,2 g 0,4299
M01AB82 Diclofenac+Omeprazole(O) 60018,75 g 0,1 g 1,2376
M01AC Oxicams 3,7597
M01AC01 Piroxicam(O) 1258,4 g 0,02 g 0,1297
M01AC05 Lornoxicam(O) 1246,24 g 0,012 g 0,2142
M01AC05 Lornoxicam(P) 4,08 g 0,012 g 0,0007
M01AC06 Meloxicam(O) 24630,525 g 0,015 g 3,3860
M01AC06 Meloxicam(P) 211,825 g 0,015 g 0,0291
M01AE Propionic acid derivatives 39,5921
M01AE01 Ibuprofen(O) 14565502 g 1,2 g 25,0292
M01AE01 Ibuprofen(P) 6586 g 1,2 g 0,0113
M01AE02 Naproxen(O) 738728,65 g 0,5 g 3,0466
M01AE03 Ketoprofen(O) 123315,625 g 0,15 g 1,6952
M01AE03 Ketoprofen(P) 13023 g 0,15 g 0,1790
M01AE03 Ketoprofen(R) 1,2 g 0,15 g <0,0001
M01AE17 Dexketoprofen(O) 75805,25 g 0,075 g 2,0842
M01AE17 Dexketoprofen(P) 3606,5 g 0,075 g 0,0992
M01AE52 Naproxen+Esomeprazole(O) 1803045 g 0,5 g 7,4360
M01AE82 Ibuprofen+Phenylephrine(O) 6561,6 g 1,2 g 0,0113
M01AG Fenamates 0,0044
M01AG02 Tolfenamic acid(O) 636 g 0,3 g 0,0044
M01AH Coxibs 9,2549
M01AH01 Celecoxib(O) 80092 g 0,2 g 0,8258
M01AH05 Etoricoxib(O) 245263,41 g 60 mg 8,4292
M01AX Other antiinflammatory and antirheumatic agents, non-steroids 7,7785
M01AX01 Nabumetone(O) 146460 g 1 g 0,3020
M01AX05 Glucosamine(O) 5438609,76 g 1,5 g 7,4765
M01C SPECIFIC ANTIRHEUMATIC AGENTS 0,0112
M01CC Penicillamine and similar agents 0,0112
M01CC01 Penicillamine(O) 2712,5 g 0,5 g 0,0112
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA10 Ketoprofen(C) 1158850 g
M02AA12 Naproxen(C) 994675 g
M02AA13 Ibuprofen(C) 13002 pieces
M02AA13 Ibuprofen(C) 902450 g
M02AA15 Diclofenac(C) 450690 pieces
M02AA15 Diclofenac(C) 32066799,7 g
M02AA81 Ibuprofen+Levomenthol(C) 1700900 g
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Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
M02AC Preparations with salicylic acid derivatives
M02AC80 Methyl salicylate+Levomenthol+Eucalyptus oil+Turpentine
oil(C) 93867 g
M02AX Other topical products for joint and muscular pain
M02AX80 Nicoboxil+Nonivamide(C) 186240 g
M02AX90 Camphor+Salicylic acid+Turpentine oil+Venenum Viperae
berus(C) 747000 g
M02AX92 Benzyl nicotinate+Nonivamide+Camphor+Turpentine
oil+Dimethyl sulfoxide(C) 747800 g
M03 MUSCLE RELAXANTS 0,9980
M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
M03AB Choline derivatives
M03AB01 Suxamethonium chloride(P) 3593 g
M03AC Other quaternary ammonium compounds
M03AC04 Atracurium besilate(P) 1583,75 g
M03AC06 Pipecuronium bromide(P) 35 g
M03AC09 Rocuronium bromide(P) 1090,25 g
M03AX Other muscle relaxants, peripherally acting agents
M03AX01 Botulinum toxin(P) 1477150 U
M03B MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS 0,9980
M03BX Other centrally acting agents 0,9980
M03BX01 Baclofen(O) 4939,25 g 0,05 g 0,2037
M03BX01 Baclofen(P) 2,6215 g 0,55 mg 0,0098
M03BX02 Tizanidine(O) 4565,04 g 0,012 g 0,7845
M04 ANTIGOUT PREPARATIONS 9,5556
M04A ANTIGOUT PREPARATIONS 9,5556
M04AA Preparations inhibiting uric acid production 9,5445
M04AA01 Allopurinol(O) 1269495,8 g 0,4 g 6,5445
M04AA03 Febuxostat(O) 116389,28 g 0,08 g 3,0000
M04AB Preparations increasing uric acid excretion 0,0032
M04AB01 Probenecid(O) 50 g 1 g 0,0001
M04AB03 Benzbromarone(O) 149 g 0,1 g 0,0031
M04AC Preparations with no effect on uric acid metabolism 0,0079
M04AC01 Colchicine(O) 3,835 g 1 mg 0,0079
M05 DRUGS FOR TREATMENT OF BONE DISEASES 4,6122
M05B DRUGS AFFECTING BONE STRUCTURE AND
MINERALIZATION 4,6122
M05BA Bisphosphonates 0,7983
M05BA03 Pamidronic acid(P) 13,89 g 0,06 g 0,0005
M05BA04 Alendronic acid(O) 223,72 g 0,01 g 0,0461
M05BA06 Ibandronic acid(O) 1364,7 g 0,005 g 0,5628
M05BA06 Ibandronic acid(P) 0,12 g 0,006 g <0,0001
M05BA07 Risedronic acid(O) 437,36 g 0,005 g 0,1804
M05BA08 Zoledronic acid(P) 16,365 g 0,004 g 0,0084
M05BB Bisphosphonates, combinations 2,6506
M05BB03 Alendronic acid+Colecalciferol(O) 12854,24 g 10 mg 2,6506
M05BX Other drugs affecting bone structure and mineralization 1,1633
M05BX04 Denosumab(P) 186,16 g 0,33 mg 1,1633
M05BX05 Burosumab(P) 1,35 g
N NERVOUS SYSTEM 142,3143
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AB Halogenated hydrocarbons
N01AB06 Isoflurane(I) 15000 ml
N01AB07 Desflurane(I) 72960 ml
N01AB08 Sevoflurane(I) 821750 ml
N01AF Barbiturates, plain
N01AF03 Thiopental(P) 1790 g
N01AH Opioid anesthetics
N01AH01 Fentanyl(I) 30,7205 g
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Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N01AH06 Remifentanil(P) 18,37 g
N01AX Other general anesthetics
N01AX03 Ketamine(P) 551 g
N01AX07 Etomidate(P) 57,2 g
N01AX10 Propofol(P) 70630 g
N01AX11 Sodium oxybate(P) 120 g
N01AX13 Nitrous oxide(I) 10162000 ml
N01AX14 Esketamine(P) 226,5 g
N01B ANESTHETICS, LOCAL
N01BA Esters of aminobenzoic acid
N01BA02 Procaine(P) 40 g
N01BB Amides
N01BB01 Bupivacaine(Infilt, P) 2841 g
N01BB01 Bupivacaine(P) 238,25 g
N01BB02 Lidocaine(C) 2050 ml
N01BB02 Lidocaine(C) 2357,5 g
N01BB02 Lidocaine(NA) 2400 ml
N01BB02 Lidocaine(NA) 5719 g
N01BB02 Lidocaine(O) 72240 g
N01BB02 Lidocaine(P) 27198,6 g
N01BB03 Mepivacaine(dental) 1443,3 g
N01BB08 Articaine(P) 0,8 g
N01BB09 Ropivacaine(P) 745,9 g
N01BB80 Articaine+Epinephrine(dental) 841840 ml
N01BB80 Articaine+Epinephrine(O) 438660 ml
N01BB81 Bupivacaine+Epinephrine(P) 250000 ml
N01BB82 Lidocaine+Epinephrine(dental) 67900 ml
N01BB83 Lidocaine+Prilocaine(C) 53945,25 g
N01BB86 Lidocaine+Chlorhexidine(urethral) 930312,5 g
N01BC Esters of benzoic acid
N01BC01 Cocaine(NA) 310 g
N01BX Other local anesthetics
N01BX04 Capsaicin(C) 75,0904 g
N02 ANALGESICS 26,7993
N02A OPIOIDS 8,8276
N02AA Natural opium alkaloids 0,8756
N02AA01 Morphine(O) 5806,8 g 0,1 g 0,1197
N02AA01 Morphine(P) 809,8 g 0,03 g 0,0557
N02AA05 Oxycodone(O) 20429,1 g 0,075 g 0,5617
N02AA05 Oxycodone(P) 228,6 g 0,03 g 0,0157
N02AA08 Dihydrocodeine(O) 8413,2 g 0,15 g 0,1157
N02AA55 Oxycodone+Naloxone(O) 260,55 g 75 mg 0,0072
N02AB Phenylpiperidine derivatives 0,1430
N02AB02 Pethidine(P) 33 g 0,4 g 0,0002
N02AB02 Pethidine(P, V) 1922,5 g 0,4 g 0,0099
N02AB03 Fentanyl(O) 3,4736 g
N02AB03 Fentanyl(SL) 3,243 g 0,6 mg 0,0111
N02AB03 Fentanyl(TD) 70,8412 g 1,2 mg 0,1217
N02AE Oripavine derivatives 0,0163
N02AE01 Buprenorphine(TD) 9,5088 g 1,2 mg 0,0163
N02AJ Opioids in combination with non-opioid analgesics 5,8990
N02AJ06 Codeine+Paracetamol(O) 6878930 pieces 3 pieces 4,7283
N02AJ13 Tramadol+Paracetamol(O) 1992 g 150 mg 0,0274
N02AJ14 Tramadol+Dexketoprofen(O) 83172,375 g 150 mg 1,1434
N02AX Other opioids 1,8936
N02AX02 Tramadol(O) 271498 g 0,3 g 1,8662
N02AX02 Tramadol(P) 3992 g 0,3 g 0,0274
N02B OTHER ANALGESICS AND ANTIPYRETICS 16,8943
N02BA Salicylic acid and derivatives 0,9381
N02BA01 Acetylsalicylic acid (O) 1178865,56 g 3 g 0,8103
N02BA01 Acetylsalicylic acid (P) 31 g
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Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N02BA80 Acetylsalicylic acid +Ascorbic acid(O) 185862,4 g 3 g 0,1278
N02BB Pyrazolones 0,0015
N02BB02 Metamizole sodium(O) 240 g 3 g 0,0002
N02BB02 Metamizole sodium(P) 1970 g 3 g 0,0014
N02BB02 Metamizole sodium(P, V) 30 g 3 g <0,0001
N02BE Anilides 15,9547
N02BE01 Paracetamol(O) 17012588,8 g 3 g 11,6937
N02BE01 Paracetamol(P) 324282 g 3 g 0,2229
N02BE01 Paracetamol(R) 58933,7 g 3 g 0,0405
N02BE52 Paracetamol+Pseudoephedrine+Diphenhydramine(O) 73336 g 3 g 0,0504
N02BE75 Paracetamol+Guaifenesin+Phenylephrine(O) 199881,5 g 3 g 0,1374
N02BE81 Paracetamol+Chlorphenamine+Pseudoephedrine+Dextrometh
orphan(O) 412106 g 3 g 0,2833
N02BE83 Paracetamol+Caffeine(O) 245446 g 3 g 0,1687
N02BE84 Paracetamol+Phenylephrine+Ascorbic acid(O) 934201,25 g 3 g 0,6421
N02BE85 Paracetamol+Pheniramine+Ascorbic acid(O) 86508,32 g 3 g 0,0595
N02BE86 Paracetamol+Phenylephrine+Terpin hydrate+Ascorbic
acid+Caffeine(O) 327030 g 3 g 0,2248
N02BE87 Paracetamol+Pseudoephedrine(O) 62200 g 3 g 0,0428
N02BE91 Paracetamol+Ascorbic acid(O) 9510,6 g 3 g 0,0065
N02BE92 Paracetamol+Codeine(O) 1050760 g 3 g 0,7222
N02BE94 Paracetamol+Codeine+Caffeine(O) 1879902 g 3 g 1,2922
N02BE95 Paracetamol+Phenylephrine(O) 69645 g 3 g 0,0479
N02BE97 Paracetamol+Pseudoephedrine+Dextromethorphan(O) 465414 g 3 g 0,3199
N02C ANTIMIGRAINE PREPARATIONS 1,0774
N02CC Selective serotonin (5HT1) agonists 1,0565
N02CC01 Sumatriptan(N) 1,2 g 0,02 g 0,0001
N02CC01 Sumatriptan(O) 21927,6 g 0,05 g 0,9043
N02CC03 Zolmitriptan(O) 66,59 g 2,5 mg 0,0549
N02CC04 Rizatriptan(O) 61,89 g 0,01 g 0,0128
N02CC07 Frovatriptan(O) 102,26 g 2,5 mg 0,0843
N02CD Calcitonin gene-related peptide (CGRP) antagonists 0,0210
N02CD01 Erenumab(P) 22,4 g 2,5 mg 0,0185
N02CD03 fremanezumab(P) 9 g 7,5 mg 0,0025
N03 ANTIEPILEPTICS 11,9146
N03A ANTIEPILEPTICS 11,9146
N03AA Barbiturates and derivatives 0,4563
N03AA02 Phenobarbital(O) 19800 g 0,1 g 0,4083
N03AA02 Phenobarbital(P) 140 g 0,1 g 0,0029
N03AA03 Primidone(O) 27350 g 1,25 g 0,0451
N03AA80 Benzobarbital(O) 150 g
N03AB Hydantoin derivatives 0,0419
N03AB02 Phenytoin(O) 5890 g 0,3 g 0,0405
N03AB02 Phenytoin(P) 200 g 0,3 g 0,0014
N03AD Succinimide derivatives 0,0134
N03AD01 Ethosuximide(O) 8150 g 1,25 g 0,0134
N03AE Benzodiazepine derivatives 0,5825
N03AE01 Clonazepam(O) 2260,02 g 0,008 g 0,5825
N03AF Carboxamide derivatives 2,7683
N03AF01 Carbamazepine(O) 944646 g 1 g 1,9479
N03AF02 Oxcarbazepine(O) 397845 g 1 g 0,8204
N03AG Fatty acid derivatives 1,7071
N03AG01 Valproic acid(O) 1227965 g 1,5 g 1,6881
N03AG01 Valproic acid(P) 1671,3 g 1,5 g 0,0023
N03AG04 Vigabatrin(O) 16200 g 2 g 0,0167
N03AX Other antiepileptics 6,3451
N03AX03 Sultiame(O) 5300 g 0,4 g 0,0273
N03AX09 Lamotrigine(O) 108935,26 g 0,3 g 0,7488
N03AX11 Topiramate(O) 39232,5 g 0,3 g 0,2697
N03AX12 Gabapentin(O) 1639378 g 1,8 g 1,8781
N03AX14 Levetiracetam(O) 582090 g 1,5 g 0,8002
31/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N03AX14 Levetiracetam(P) 690 g 1,5 g 0,0009
N03AX15 Zonisamide(O) 14 g 0,2 g 0,0001
N03AX16 Pregabalin(O) 380276,4 g 0,3 g 2,6139
N03AX17 Stiripentol(O) 1320 g 1 g 0,0027
N03AX18 Lacosamide(O) 39,9 g 0,3 g 0,0003
N03AX22 perampanel(O) 2,016 g 8 mg 0,0005
N03AX23 Brivaracetam(O) 124,6 g 0,1 g 0,0026
N03AX24 Cannabidiol(O) 120 g
N04 ANTI-PARKINSON DRUGS 3,7745
N04A ANTICHOLINERGIC AGENTS 0,5833
N04AA Tertiary amines 0,5833
N04AA01 Trihexyphenidyl(O) 2828,8 g 0,01 g 0,5833
N04B DOPAMINERGIC AGENTS 3,1911
N04BA Dopa and dopa derivatives 1,4809
N04BA03 Levodopa +Carbidopa+Entacapone(O) 72982,5 g 0,45 g 0,3344
N04BA80 Levodopa +Benserazide(O) 324140 g 0,6 g 1,1140
N04BA81 Levodopa +Carbidopa(intestin) 20132 g
N04BA81 Levodopa +Carbidopa(O) 9446 g 0,6 g 0,0325
N04BB Adamantane derivatives 0,3144
N04BB01 Amantadine(O) 30490 g 0,2 g 0,3144
N04BB01 Amantadine(P) 26 g
N04BC Dopamine agonists 0,7696
N04BC04 Ropinirole(O) 1080,996 g 0,006 g 0,3715
N04BC05 Pramipexole(O) 445,4819 g 2,5 mg 0,3674
N04BC07 Apomorphine(P) 297,05 g 20 mg 0,0306
N04BD Monoamine oxidase type B inhibitors 0,6263
N04BD02 Rasagiline(O) 303,726 g 0,001 g 0,6263
N05 PSYCHOLEPTICS 45,4010
N05A ANTIPSYCHOTICS 10,0797
N05AA Phenothiazines with aliphatic side-chain 0,1472
N05AA01 Chlorpromazine(O) 10418,5 g 0,3 g 0,0716
N05AA01 Chlorpromazine(P) 37,5 g 0,1 g 0,0008
N05AA02 Levomepromazine(O) 10852,5 g 0,3 g 0,0746
N05AA02 Levomepromazine(P, V) 12,5 g 0,1 g 0,0003
N05AB Phenothiazines with piperazine structure 0,0866
N05AB02 Fluphenazine(P) 8,625 g 0,001 g 0,0178
N05AB03 Perphenazine(O) 436,4 g 0,03 g 0,0300
N05AB03 Perphenazine(P) 188,268 g 0,01 g 0,0388
N05AB04 Prochlorperazine(O) 0,82 g 0,1 g <0,0001
N05AC Phenothiazines with piperidine structure 0,0009
N05AC01 Periciazine(O) 21,6 g 0,05 g 0,0009
N05AD Butyrophenone derivatives 1,0486
N05AD01 Haloperidol(O) 1988,735 g 0,008 g 0,5126
N05AD01 Haloperidol(P) 1014,575 g 0,008 g 0,2615
N05AD03 Melperone(O) 37695 g 0,3 g 0,2591
N05AD08 Droperidol(P) 18,675 g 2,5 mg 0,0154
N05AE Indole derivatives 0,0824
N05AE03 Sertindole(O) 621,664 g 0,016 g 0,0801
N05AE04 Ziprasidone(O) 89,36 g 0,08 g 0,0023
N05AF Thioxanthene derivatives 0,8488
N05AF01 Flupentixol(O) 363,75 g 0,006 g 0,1250
N05AF01 Flupentixol(P) 124 g 0,004 g 0,0639
N05AF03 Chlorprothixene(O) 29357,5 g 0,3 g 0,2018
N05AF05 Zuclopenthixol(O) 1340,5 g 0,03 g 0,0921
N05AF05 Zuclopenthixol(P) 49,5 g 0,03 g 0,0034
N05AF05 Zuclopenthixol(P) 2637,2 g 0,015 g 0,3625
N05AH Diazepines, oxazepines and thiazepines 5,7949
N05AH02 Clozapine(O) 99170,5 g 0,3 g 0,6817
N05AH03 Olanzapine(O) 11305,56 g 0,01 g 2,3313
N05AH03 Olanzapine(P) 195,16 g 0,01 g 0,0402
N05AH04 Quetiapine(O) 531841 g 0,4 g 2,7417
32/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N05AL Benzamides 0,1349
N05AL01 Sulpiride(O) 20110,5 g 0,8 g 0,0518
N05AL05 Amisulpride(O) 16122 g 0,4 g 0,0831
N05AN Lithium 0,2947
N05AN01 Lithium(O) 128610 g 0,9 g 0,2947
N05AX Other antipsychotics 1,6406
N05AX08 Risperidone(O) 1662,3 g 0,005 g 0,6856
N05AX08 Risperidone(P) 21,7625 g 2,7 mg 0,0166
N05AX12 Aripiprazole(O) 5597,22 g 0,015 g 0,7695
N05AX12 Aripiprazole(P) 9,5842 g 0,015 g 0,0013
N05AX12 Aripiprazole(P) 542,8 g 0,0133 g 0,0842
N05AX13 Paliperidone(P) 98,05 g 2,5 mg 0,0809
N05AX15 Cariprazine(O) 3,738 g 3 mg 0,0026
N05B ANXIOLYTICS 13,1656
N05BA Benzodiazepine derivatives 13,1650
N05BA01 Diazepam(O) 27486,95 g 0,01 g 5,6680
N05BA01 Diazepam(P) 467,3 g 0,01 g 0,0964
N05BA01 Diazepam(R) 63,075 g 0,01 g 0,0130
N05BA04 Oxazepam(O) 1 g 0,05 g <0,0001
N05BA06 Lorazepam(O) 871,71 g 2,5 mg 0,7190
N05BA06 Lorazepam(P) 10,22 g 2,5 mg 0,0084
N05BA08 Bromazepam(O) 5899,53 g 0,01 g 1,2165
N05BA09 Clobazam(O) 326 g 0,02 g 0,0336
N05BA12 Alprazolam(O) 2615,3425 g 0,001 g 5,3930
N05BA80 Phenazepam(O) 8,25 g 0,001 g 0,0170
N05BB Diphenylmethane derivatives 0,0001
N05BB01 Hydroxyzine(O) 3,6 g 0,075 g 0,0001
N05BE Azaspirodecanedione derivatives 0,0005
N05BE01 Buspirone(O) 7,2 g 0,03 g 0,0005
N05C HYPNOTICS AND SEDATIVES 22,1557
N05CD Benzodiazepine derivatives 0,1658
N05CD02 Nitrazepam(O) 209,35 g 0,005 g 0,0863
N05CD05 Triazolam(O) 0,0075 g 0,25 mg 0,0001
N05CD08 Midazolam(O) 0,04 g 0,01 g <0,0001
N05CD08 Midazolam(O) 80,9507 g 0,015 g 0,0111
N05CD08 Midazolam(P) 491,0807 g 0,015 g 0,0675
N05CD08 Midazolam(P, R) 5,25 g 0,015 g 0,0007
N05CF Benzodiazepine related drugs 21,3986
N05CF01 Zopiclone(O) 61256,925 g 7,5 mg 16,8421
N05CF02 Zolpidem(O) 22096,6 g 0,01 g 4,5565
N05CH Melatonin receptor agonists 0,2853
N05CH01 Melatonin(O) 276,71 g 2 mg 0,2853
N05CM Other hypnotics and sedatives 0,3061
N05CM09 Valerianae radix(O) 421890 pieces 3 pieces 0,2900
N05CM18 Dexmedetomidine(P) 7,8008 g 1 mg 0,0161
N06 PSYCHOANALEPTICS 42,2154
N06A ANTIDEPRESSANTS 37,1049
N06AA Non-selective monoamine reuptake inhibitors 1,9309
N06AA02 Imipramine(O) 6,25 g 0,1 g 0,0001
N06AA04 Clomipramine(O) 4758,45 g 0,1 g 0,0981
N06AA04 Clomipramine(P) 2,5 g 0,1 g 0,0001
N06AA09 Amitriptyline(O) 54730,5 g 0,075 g 1,5048
N06AA10 Nortriptyline(O) 11922,5 g 0,075 g 0,3278
N06AB Selective serotonin reuptake inhibitors 21,7827
N06AB03 Fluoxetine(O) 31871,4 g 0,02 g 3,2861
N06AB04 Citalopram(O) 13786,54 g 0,02 g 1,4214
N06AB05 Paroxetine(O) 22537,8 g 0,02 g 2,3237
N06AB06 Sertraline(O) 146511,2 g 0,05 g 6,0423
N06AB08 Fluvoxamine(O) 432 g 0,1 g 0,0089
N06AB10 Escitalopram(O) 42191,8 g 0,01 g 8,7002
N06AF Monoamine oxidase inhibitors, non-selective 0,0091
33/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N06AF04 Tranylcypromine(O) 44 g 0,01 g 0,0091
N06AG Monoamine oxidase type A inhibitors 0,0001
N06AG02 Moclobemide(O) 18 g 0,3 g 0,0001
N06AX Other antidepressants 13,3822
N06AX03 Mianserin(O) 31,8 g 0,06 g 0,0011
N06AX05 Trazodone(O) 15279 g 0,3 g 0,1050
N06AX11 Mirtazapine(O) 38672,46 g 0,03 g 2,6582
N06AX12 Bupropione(O) 128682 g 0,3 g 0,8845
N06AX14 Tianeptine(O) 22753,5 g 0,0375 g 1,2512
N06AX16 Venlafaxine(O) 190464,75 g 0,1 g 3,9275
N06AX18 Reboxetine(O) 0,72 g 0,008 g 0,0002
N06AX21 Duloxetine(O) 74708,04 g 0,06 g 2,5676
N06AX22 Agomelatine(O) 15207,5 g 0,025 g 1,2544
N06AX26 Vortioxetine(O) 3552,64 g 10 mg 0,7326
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND
NOOTROPICS 1,5304
N06BA Centrally acting sympathomimetics 1,2658
N06BA04 Methylphenidate(O) 17228,1 g 0,03 g 1,1842
N06BA07 Modafinil(O) 1179 g 0,3 g 0,0081
N06BA09 Atomoxetine(O) 2853,62 g 0,08 g 0,0736
N06BA12 Lisdexamfetamine dimesylate(O) 7,2 g
N06BC Xanthine derivatives
N06BC81 Caffeine citrate(O, P) 63,6 g
N06BX Other psychostimulants and nootropics 0,2646
N06BX03 Piracetam (O) 295680 g 2,4 g 0,2540
N06BX13 Idebenone(O) 243 g 0,9 g 0,0006
N06BX18 Vinpocetine(O) 72,75 g 15 mg 0,0100
N06BX83 Aminobutyric acid(O) 33115 g
N06D ANTI-DEMENTIA DRUGS 3,5801
N06DA Anticholinesterases 1,1041
N06DA02 Donepezil(O) 4015,76 g 7,5 mg 1,1041
N06DX Other anti-dementia drugs 2,4760
N06DX01 Memantine(O) 4535,52 g 0,02 g 0,4676
N06DX02 Ginkgo folium(O) 116874 g 0,12 g 2,0084
N06DX80 cerebrolysine(P) 4,304 g
N07 OTHER NERVOUS SYSTEM DRUGS 12,2094
N07A PARASYMPATHOMIMETICS 0,3739
N07AA Anticholinesterases 0,3739
N07AA01 neostigmine(O) 1,8 g 0,06 g 0,0001
N07AA01 neostigmine(P) 33,545 g 0,002 g 0,0346
N07AA02 Pyridostigmine bromide(O) 27189 g 0,18 g 0,3115
N07AA03 Distigmine bromide(O) 3,1 g 0,005 g 0,0013
N07AA80 Neostigmine+Glycopyrronium(P) 12850 ml 1 ml 0,0265
N07AX Other parasympathomimetics
N07AX01 Pilocarpine(O) 1,68 g
N07B DRUGS USED IN ADDICTIVE DISORDERS 3,3984
N07BA Drugs used in nicotine dependence 1,8655
N07BA01 Nicotine(O) 17003,7 g 0,03 g 1,1688
N07BA01 Nicotine(TD) 4441,738 g 0,014 g 0,6542
N07BA03 Varenicline(O) 41,222 g 2 mg 0,0425
N07BB Drugs used in alcohol dependence 0,3664
N07BB01 Disulfiram(O) 28410 g 0,2 g 0,2929
N07BB01 Disulfiram(P) 106 g
N07BB03 Acamprosate(O) 447,552 g 2 g 0,0005
N07BB04 Naltrexone(O) 1549,8 g 50 mg 0,0639
N07BB05 nalmefene(O) 79,632 g 18 mg 0,0091
N07BC Drugs used in opioid dependence 1,1665
N07BC02 Methadone(O) 13520 g 0,025 g 1,1152
N07BC51 Buprenorphine+Naloxone(SL) 199,234 g 8 mg 0,0514
N07C ANTIVERTIGO PREPARATIONS 8,4046
N07CA Antivertigo preparations 8,4046
34/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N07CA01 Betahistine(O) 83376,48 g 0,024 g 7,1637
N07CA02 Cinnarizine(O) 51360 g 0,09 g 1,1768
N07CA03 Flunarizine(O) 4,5 g 0,01 g 0,0009
N07CA80 Cinnarizine+Dimenhydrinate(O) 2762 g 90 mg 0,0633
N07X OTHER NERVOUS SYSTEM DRUGS 0,0324
N07XX Other nervous system drugs 0,0324
N07XX02 Riluzole(O) 1352,4 g 0,1 g 0,0279
N07XX06 Tetrabenazine(O) 168 g 0,1 g 0,0035
N07XX07 Fampridine(O) 10,64 g 20 mg 0,0011
N07XX14 Edaravone(P) 8,1 g
P ANTIPARASITIC PRODUCTS, INSECTICIDES AND
REPELLENTS 1,0260
P01 ANTIPROTOZOALS 0,8172
P01A AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL
DISEASES
P01AB Nitroimidazole derivatives
P01AB01 Metronidazole (O, V) 1062 g
P01B ANTIMALARIALS 0,8172
P01BA Aminoquinolines 0,7762
P01BA02 Hydroxychloroquine(O) 194124 g 0,516 g 0,7758
P01BA03 Primaquine(O) 3 g 0,015 g 0,0004
P01BB Biguanides 0,0407
P01BB51 Proguanil+Atovaquone(O) 648 pieces 16 pieces 0,0001
P01BB51 Proguanil+Atovaquone(O) 78852 pieces 4 pieces 0,0406
P01BD Diaminopyrimidines 0,0003
P01BD01 Pyrimethamine(O) 10,5 g 0,075 g 0,0003
P01BE Artemisinin and derivatives, plain <0,0001
P01BE03 Artesunate(P) 0,6 g 0,28 g <0,0001
P02 ANTHELMINTICS 0,2088
P02B ANTITREMATODALS 0,0002
P02BA Quinoline derivatives and related substances 0,0002
P02BA01 Praziquantel(O) 313,2 g 3 g 0,0002
P02C ANTINEMATODAL AGENTS 0,2086
P02CA Benzimidazole derivatives 0,2083
P02CA01 Mebendazole(O) 18001 g 0,2 g 0,1856
P02CA03 Albendazole(O) 4400 g 0,4 g 0,0227
P02CF Avermectines 0,0003
P02CF01 Ivermectin(O) 1,746 g 12 mg 0,0003
P03 ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES
AND REPELLENTS
P03A ECTOPARASITICIDES, INCL. SCABICIDES
P03AC Pyrethrines, incl. synthetic compounds
P03AC04 Permethrin(C) 74760 g
P03AX Other ectoparasiticides, incl. scabicides
P03AX01 Benzyl benzoate(C) 351330 g
R RESPIRATORY SYSTEM 91,8504
R01 NASAL PREPARATIONS 36,2791
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS
FOR TOPICAL USE 34,1838
R01AA Sympathomimetics, plain 22,0028
R01AA05 Oxymetazoline(N) 281,8575 g 0,4 mg 1,4530
R01AA07 Xylometazoline(N) 7972,5 g 0,8 mg 20,5498
R01AB Sympathomimetics, combinations excl. corticosteroids 3,0514
R01AB83 Xylometazoline+Ipratropium bromide(N) 193840 ml 0,8 ml 0,4996
R01AB85 Xylometazoline+Dexpanthenol(N) 989980 ml 0,8 ml 2,5518
R01AC Antiallergic agents, excl. corticosteroids 0,3533
R01AC03 Azelastine(N) 95,94 g 0,56 mg 0,3533
R01AD Corticosteroids 8,7763
R01AD01 Beclometasone(N) 6,31 g 0,4 mg 0,0325
R01AD05 Budesonide(N) 37,4907 g 0,2 mg 0,3865
R01AD08 Fluticasone(N) 84,759 g 0,2 mg 0,8739
35/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R01AD09 Mometasone(N) 370,468 g 0,2 mg 3,8197
R01AD12 Fluticasone furoate(N) 168,9567 g 0,11 mg 3,1673
R01AD81 Fluticasone+Azelastine(N) 963000 doses 4 doses 0,4964
R01AX Other nasal preparations
R01AX06 Mupirocin(N) 120 g
R01AX83 Retinol+Tocopherol(N) 142880 ml
R01B NASAL DECONGESTANTS FOR SYSTEMIC USE 2,0952
R01BA Sympathomimetics 2,0952
R01BA02 Pseudoephedrine(O) 140291,52 g 0,24 g 1,2054
R01BA81 Pseudoephedrine+Triprolidine(O) 28360,68 g 0,24 g 0,2437
R01BA84 Pseudoephedrine+Guaifenesin(O) 9138,6 g 0,24 g 0,0785
R01BA89 Pseudoephedrine+Loratadine(O) 10970,4 g 0,24 g 0,0943
R01BA93 Pseudoephedrine+Cetirizine(O) 55100,64 g 0,24 g 0,4734
R02 THROAT PREPARATIONS 2,7242
R02A THROAT PREPARATIONS 2,7242
R02AA Antiseptics 2,2405
R02AA06 Cetylpyridinium chloride(O) 18324 pieces
R02AA82 Benzydamine+Cetylpyridinium chloride(O) 852720 ml
R02AA82 Benzydamine+Cetylpyridinium chloride(O) 2008368 pieces 6 pieces 0,6902
R02AA89 Povidone, iodinated+Allantoin(O) 327330 ml
R02AA92 Dequalinium+Cinchocaine(O) 1115720 pieces 6 pieces 0,3834
R02AA94 Amylmetacresol+Dichlorobenzyl alcohol(O) 961920 pieces 6 pieces 0,3306
R02AA95 Amylmetacresol+Dichlorobenzyl alcohol+Levomenthol(O) 1664472 pieces 6 pieces 0,5720
R02AA96 Amylmetacresol+Dichlorobenzyl alcohol+Ascorbic acid(O) 641376 pieces 6 pieces 0,2204
R02AA98 Cetylpyridinium chloride+Benzocaine(O) 127458 pieces 6 pieces 0,0438
R02AD Anesthetics, local 0,1260
R02AD80 Lidocaine+Propyl parahydroxybenzoate(O) 366660 pieces 6 pieces 0,1260
R02AX Other throat preparations 0,3577
R02AX01 Flurbiprofen(O) 7631,89 g 44 mg 0,3577
R02AX80 Thyme herb+Sage leaf(O) 30150 ml
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES 28,0422
R03A ADRENERGICS, INHALANTS 20,4007
R03AC Selective beta-2-adrenoceptor agonists 3,9206
R03AC02 Salbutamol(I) 984,42 g 0,8 mg 2,5374
R03AC02 Salbutamol(I) 1286 g 0,01 g 0,2652
R03AC04 Fenoterol(I) 62,38 g 0,6 mg 0,2144
R03AC12 Salmeterol(I) 4,638 g 0,1 mg 0,0956
R03AC13 Formoterol(I) 5,7728 g 0,024 mg 0,4960
R03AC18 Indacaterol(I) 22,6935 g 0,15 mg 0,3120
R03AK Adrenergics in combination with corticosteroids or other drugs,
excl. anticholinergics 12,6544
R03AK06 Salmeterol+Fluticasone(I) 576480 doses 4 doses 0,2972
R03AK06 Salmeterol+Fluticasone(I) 2395860 doses 2 doses 2,4702
R03AK07 Formoterol+Budesonide(I) 1105440 doses 2 doses 1,1397
R03AK07 Formoterol+Budesonide(I) 6400680 doses 4 doses 3,2997
R03AK08 Formoterol+Beclometasone(I) 3452760 doses 4 doses 1,7800
R03AK10 Vilanterol+Fluticasone furoate(I) 1739040 doses 1 doses 3,5860
R03AK13 Salbutamol+Beclometasone(I) 158400 doses 4 doses 0,0817
R03AL Adrenergics in combinations with anticholinergics incl. triple
combinations with corticosteroids 3,8256
R03AL01 Fenoterol+Ipratropium bromide(I) 205720 ml 16 ml 0,0265
R03AL01 Fenoterol+Ipratropium bromide(I) 2713600 doses 6 doses 0,9326
R03AL03 Vilanterol+Umeclidinium(I) 355590 doses 1 doses 0,7333
R03AL04 Indacaterol+Glycopyrronium(I) 191370 doses 1 doses 0,3946
R03AL05 Formoterol+Aclidinium(I) 369240 doses 2 doses 0,3807
R03AL06 Olodaterol+Tiotropium(I) 699120 doses 2 doses 0,7208
R03AL07 Formoterol+Glycopyrronium(I) 195120 doses 4 doses 0,1006
R03AL08 Vilanterol+Umeclidinium+Fluticasone furoate(I) 72990 doses 1 doses 0,1505
R03AL09 Formoterol+Glycopyrronium+Beclometasone(I) 748800 doses 4 doses 0,3860
36/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES,
INHALANTS 4,7057
R03BA Glucocorticoids 1,5566
R03BA02 Budesonide(I) 149,2 g 1,5 mg 0,2051
R03BA02 Budesonide(I) 305,864 g 0,8 mg 0,7884
R03BA05 Fluticasone(I) 163,857 g 0,6 mg 0,5631
R03BB Anticholinergics 3,1491
R03BB01 Ipratropium bromide(I) 21,108 g 0,12 mg 0,3627
R03BB01 Ipratropium bromide(I) 21,625 g 0,3 mg 0,1486
R03BB04 Tiotropium(I) 3,4729 g 0,005 mg 1,4323
R03BB05 Aclidinium(I) 136,8242 g 0,644 mg 0,4381
R03BB06 Glycopyrronium(I) 7,4712 g 44 mcg 0,3501
R03BB07 Umeclidinium(I) 11,1276 g 55 mcg 0,4172
R03C ADRENERGICS FOR SYSTEMIC USE 0,0872
R03CC Selective beta-2-adrenoceptor agonists 0,0872
R03CC02 Salbutamol(O) 507,06 g 0,012 g 0,0871
R03CC02 Salbutamol(P) 0,327 g 0,012 g 0,0001
R03D OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY
DISEASES 2,8486
R03DA Xanthines 1,1525
R03DA04 Theophylline(O) 219340 g 0,4 g 1,1307
R03DA05 Aminophylline(O) 22,5 g 0,1 g 0,0005
R03DA05 Aminophylline(O) 36 g 0,6 g 0,0001
R03DA05 Aminophylline(P) 6174,8 g 0,6 g 0,0212
R03DC Leukotriene receptor antagonists 1,6247
R03DC03 Montelukast(O) 7878,808 g 0,01 g 1,6247
R03DX Other systemic drugs for obstructive airway diseases 0,0714
R03DX05 Omalizumab(P) 224,1 g 0,016 g 0,0289
R03DX07 Roflumilast(O) 0,18 g 0,5 mg 0,0007
R03DX09 Mepolizumab(P) 40,5 g 3,6 mg 0,0232
R03DX10 Benralizumab(P) 4,86 g 0,54 mg 0,0186
R05 COUGH AND COLD PREPARATIONS 6,8646
R05C EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH
SUPPRESSANTS 6,7464
R05CA Expectorants 0,0644
R05CA03 Guaifenesin(O) 28116 g 0,9 g 0,0644
R05CA12 Hederae helicis folium(O) 216938 pieces
R05CA12 Hederae helicis folium(O) 5806120 ml
R05CA86 Iceland moss(O) 6406500 ml
R05CA87 Distillate of rectified essential oils of eucalyptus, sweet orange,
myrtle and lemon(O) 1122820 pieces
R05CA88 Thyme herb+Wild thyme+Plantain(O) 320800 ml
R05CA89 Thyme herb+Hederae helicis folium(O) 248400 ml
R05CA91 Thyme herb+Marshmallow root(O) 183940 pieces
R05CA91 Thyme herb+Marshmallow root(O) 3851760 ml
R05CA92 Thyme herb(O) 162660 pieces
R05CB Mucolytics 6,6820
R05CB01 Acetylcysteine(I, P) 225 g
R05CB01 Acetylcysteine(O) 985524,8 g 0,5 g 4,0644
R05CB01 Acetylcysteine(P) 7968 g
R05CB02 Bromhexine(O) 7499,12 g 0,024 g 0,6443
R05CB03 Carbocisteine(O) 136752,5 g 1,5 g 0,1880
R05CB06 Ambroxol(O) 102684,75 g 0,12 g 1,7645
R05CB13 Dornase alfa(I) 25,14 g 2,5 mg 0,0207
R05D COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH
EXPECTORANTS 0,0759
R05DB Other cough suppressants 0,0759
R05DB09 Oxeladin(O) 2945,75 g 0,08 g 0,0759
R05F COUGH SUPPRESSANTS AND EXPECTORANTS,
COMBINATIONS 0,0422
R05FA Opium derivatives and expectorants 0,0422
37/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R05FA80 Codeine+Guaifenesin(O) 614250 ml 30 ml 0,0422
R05X OTHER COLDPREPARATIONS
R05XA Other cold combination preparations
R05XA80 Gentian root+Primula flower+Common sorrel+Elder
flower+Verbena herb(O) 3102,4 g
R05XA80 Gentian root+Primula flower+Common sorrel+Elder
flower+Verbena herb(O) 1401770 pieces
R05XA82 Ibuprofen+Pseudoephedrine(O) 5733,6 g
R06 ANTIHISTAMINES FOR SYSTEMIC USE 17,9399
R06A ANTIHISTAMINES FOR SYSTEMIC USE 17,9399
R06AA Aminoalkyl ethers 0,4810
R06AA02 Diphenhydramine(O) 19 g 0,2 g 0,0002
R06AA02 Diphenhydramine(P) 30,1 g
R06AA04 Clemastine(O) 425,96 g 0,002 g 0,4392
R06AA04 Clemastine(P) 40,4 g 0,002 g 0,0417
R06AE Piperazine derivatives 8,9059
R06AE07 Cetirizine(O) 40804,27 g 0,01 g 8,4141
R06AE09 Levocetirizine(O) 1192,55 g 0,005 g 0,4918
R06AX Other antihistamines for systemic use 8,5530
R06AX02 Cyproheptadine(O) 0,12 g 0,012 g <0,0001
R06AX13 Loratadine(O) 18549,3 g 0,01 g 3,8250
R06AX15 Mebhydrolin(O) 10 g 0,2 g 0,0001
R06AX17 Ketotifen(O) 1,32 g 0,002 g 0,0014
R06AX22 Ebastine(O) 7202,1 g 0,01 g 1,4851
R06AX27 Desloratadine(O) 2485,37 g 0,005 g 1,0250
R06AX28 Rupatadine(O) 941,12 g 0,01 g 0,1941
R06AX29 Bilastine(O) 19614,2 g 20 mg 2,0223
R07 OTHER RESPIRATORY SYSTEM PRODUCTS 0,0004
R07A OTHER RESPIRATORY SYSTEM PRODUCTS 0,0004
R07AA Lung surfactants 0,0004
R07AA81 Porcine lung phospholipids(endotrach) 33,48 g 0,16 g 0,0004
S SENSORY ORGANS 32,8766
S01 OPHTHALMOLOGICALS 32,8766
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA01 Chloramphenicol(S) 168710 ml
S01AA02 Chlortetracycline(S) 0,75 g
S01AA12 Tobramycin(S) 34485 ml
S01AA12 Tobramycin(S) 47820,5 g
S01AA13 Fusidic acid(S) 35950 g
S01AD Antivirals
S01AD02 Trifluridine(S) 5 ml
S01AD03 Aciclovir(S) 3159 g
S01AE Fluoroquinolones
S01AE03 Ciprofloxacin(S) 12430 ml
S01AE05 Levofloxacin(S) 25485 ml
S01AE07 Moxifloxacin(S) 15465 ml
S01AX Other antiinfectives
S01AX15 Propamidine(S) 130 ml
S01AX18 Povidone, iodinated(S) 472 ml
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA01 Dexamethasone(S) 162 pieces
S01BA01 Dexamethasone(S) 15035,6 g
S01BA01 Dexamethasone(S) 142710 ml
S01BA02 Hydrocortisone(S) 4206 g
S01BA09 Clobetasone(S) 12500 ml
S01BA14 Loteprednol(S) 1305 ml
S01BC Antiinflammatory agents, non-steroids
S01BC03 Diclofenac(S) 30 ml
S01BC05 Ketorolac(S) 11500 ml
38/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
S01BC10 Nepafenac(S) 19645 ml
S01BC11 Bromfenac(S) 12760 ml
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN
COMBINATION
S01CA Corticosteroids and antiinfectives in combination
S01CA80 Dexamethasone+Neomycin+Polymyxin B(S) 43670 ml
S01CA81 Dexamethasone+Tobramycin(S) 13639,5 g
S01CA81 Dexamethasone+Tobramycin(S) 37545 ml
S01CA82 Dexamethasone+Chloramphenicol(S) 47792,5 g
S01CA82 Dexamethasone+Chloramphenicol(S) 434070 ml
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS 32,8766
S01EA Sympathomimetics in glaucoma therapy 0,0516
S01EA05 Brimonidine(S) 5000 ml 0,2 ml 0,0516
S01EB Parasympathomimetics 0,0150
S01EB01 Pilocarpine(S) 2225 ml 0,4 ml 0,0115
S01EB02 Carbachol(S) 690 ml 0,4 ml 0,0036
S01EB09 Acetylcholine chloride(S) 0,2 g
S01EC Carbonic anhydrase inhibitors 3,7275
S01EC01 Acetazolamide(O) 26335 g 0,75 g 0,0724
S01EC01 Acetazolamide(P) 97 g 0,75 g 0,0003
S01EC03 Dorzolamide(S) 140115 ml 0,3 ml 0,9631
S01EC04 Brinzolamide(S) 163050 ml 0,2 ml 1,6811
S01EC80 Brinzolamide+Brimonidine(S) 98025 ml 0,2 ml 1,0107
S01ED Beta blocking agents 20,5307
S01ED01 Timolol(S) 20510 ml 0,2 ml 0,2115
S01ED01 Timolol(S) 226900 g 40 mg 11,6971
S01ED02 Betaxolol(S) 83585 ml 0,2 ml 0,8618
S01ED80 Timolol+Dorzolamide(S) 295210 ml 0,2 ml 3,0437
S01ED81 Timolol+Travoprost(S) 41442,5 ml 0,2 ml 0,4273
S01ED82 Timolol+Bimatoprost(S) 110142 ml 0,2 ml 1,1356
S01ED83 Timolol+Brinzolamide(S) 224240 ml 0,2 ml 2,3120
S01ED84 Timolol+Latanoprost(S) 73267,5 ml 0,2 ml 0,7554
S01ED85 Timolol+Tafluprost(S) 8377,8 ml 0,2 ml 0,0864
S01EE Prostaglandin analogues 8,5518
S01EE01 Latanoprost(S) 269522,5 ml 0,1 ml 5,5577
S01EE03 Bimatoprost(S) 276 ml 0,1 ml 0,0057
S01EE04 Travoprost(S) 64497,5 ml 0,1 ml 1,3300
S01EE05 Tafluprost(S) 241272 ml 0,3 ml 1,6584
S01F MYDRIATICS AND CYCLOPLEGICS
S01FA Anticholinergics
S01FA01 Atropine(S) 640 ml
S01FA04 Cyclopentolate(S) 26520 ml
S01FA06 Tropicamide(S) 13150 ml
S01FB Sympathomimetics excl. antiglaucoma preparations
S01FB01 Phenylephrine(S) 6270 ml
S01G DECONGESTANTS AND ANTIALLERGICS
S01GA Sympathomimetics used as decongestants
S01GA02 Tetryzoline(S) 260730 ml
S01GX Other antiallergics
S01GX01 Cromoglicic acid(S) 103170 ml
S01GX07 Azelastine(S) 39960 ml
S01GX09 Olopatadine(S) 22255 ml
S01H LOCAL ANESTHETICS
S01HA Local anesthetics
S01HA03 Tetracaine(S) 25390 ml
S01HA04 Proxymetacaine(S) 33285 ml
S01J DIAGNOSTIC AGENTS
S01JA Colouring agents
S01JA01 Fluorescein(P) 4500 ml
S01JA81 Fluorescein+Oxybuprocaine+Chlorobutanol(S) 2650 ml
S01K SURGICAL AIDS
39/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
S01KA Viscoelastic substances
S01KA02 Hypromellose(S) 5250 g
S01L OCULAR VASCULAR DISORDER AGENTS
S01LA Antineovascularisation agents
S01LA01 Verteporfin(P) 2 pieces
S01LA04 Ranibizumab(S) 1 pieces
S01LA05 aflibercept(S) 191 pieces
S01X OTHER OPHTHALMOLOGICALS
S01XA Other ophthalmologicals
S01XA03 Sodium chloride(S) 227,5 g
S01XA18 Ciclosporin(S) 4671 ml
S01XA80 Retinol+Dexpanthenol(S) 8172,5 g
S01XA81 Carbomer(S) 196380 g
S01XA82 Hypromellose(S) 169750 ml
S01XA85 Hypromellose+Dextran(S) 353100 ml
S02 OTOLOGICALS
S02C CORTICOSTEROIDS AND ANTIINFECTIVES IN
COMBINATION
S02CA Corticosteroids and antiinfectives in combination
S02CA81 Dexamethasone+Neomycin+Acetic acid, glacial(A) 3770 ml
S02CA82 Hydrocortisone+Ciprofloxacin(A) 131210 ml
S02D OTHER OTOLOGICALS
S02DA Analgesics and anesthetics
S02DA81 Phenazone+Lidocaine(A) 1530 ml
T HERBAL MEDICINAL PRODUCTS
T01 HERBAL MEDICINAL PRODUCTS
T01R HERBAL MEDICINAL PRODUCTS
T01RS Herbal medicinal products
T01RS01 herbal preparation(O) 676890 pieces
T01RS01 herbal preparation(O) 7993240 ml
T01RS02 homeopathic preparations(A) 5470 ml
T01RS02 homeopathic preparations(C) 549650 g
T01RS02 homeopathic preparations(O) 1680 g
T01RS02 homeopathic preparations(O) 1124710 ml
T01RS02 homeopathic preparations(O) 1270430 pieces
T01RS02 homeopathic preparations(R) 12 pieces
V VARIOUS 0,2149
V01 ALLERGENS
V01A ALLERGENS
V01AA Allergen extracts
V01AA02 Grass pollen(O) 151 pieces
V01AA02 Grass pollen(P) 165 pieces
V01AA03 House dust mites(O) 264 pieces
V01AA03 House dust mites(P) 12 ml
V01AA03 House dust mites(P) 285 pieces
V01AA05 Tree pollen(P) 495 pieces
V01AA05 Tree pollen(SL) 642 pieces
V01AA07 Allergen products (insects)(P) 534 pieces
V01AA11 Animals(O) 39 pieces
V01AA80 Tree and grass pollen(O) 111 pieces
V01AA80 Tree and grass pollen(P) 99 pieces
V01AA83 Grass pollen+Flowers(O) 5 pieces
V01AA84 Tree and flower pollen(O) 12 pieces
V03 ALL OTHER THERAPEUTIC PRODUCTS 0,2149
V03A ALL OTHER THERAPEUTIC PRODUCTS 0,2149
V03AB Antidotes
V03AB06 Sodium thiosulphate(P) 450 g
V03AB09 Dimercaprol(P) 4,8 g
V03AB14 Protamine sulfate(P) 285 g
V03AB15 Naloxone(N) 3,6 g
V03AB15 Naloxone(P) 2,272 g
40/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
V03AB16 Ethanol(P) 10900 ml
V03AB17 Methylthioninium chloride(P) 173 g
V03AB19 Physostigmine(P) 0,06 g
V03AB21 Potassium iodide(O) 13 g
V03AB24 Digitalis antitoxin(P) 3,44 g
V03AB25 Flumazenil(P) 0,29 g
V03AB33 Hydroxocobalamin(P) 80 g
V03AB34 Fomepizole(P) 20 g
V03AB35 Sugammadex(P) 104 g
V03AB37 Idarucizumab(P) 270 g
V03AB80 Sodium calcium edetate(P) 40 g
V03AC Iron chelating agents
V03AC01 Deferoxamine(P) 50 g
V03AC03 Deferasirox(O) 7695 g
V03AE Drugs for treatment of hyperkalemia and hyperphosphatemia 0,1501
V03AE01 Polystyrene sulfonate(O, R) 1826350,5 g 45 g 0,0837
V03AE02 Sevelamer(O) 155664 g 6,4 g 0,0502
V03AE03 Lanthan(O) 17752,5 g 2,25 g 0,0163
V03AF Detoxifying agents for antineoplastic treatment 0,0647
V03AF01 Mesna(P) 4188 g
V03AF03 Calcium folinate(O) 30,6 g 0,06 g 0,0011
V03AF07 Rasburicase(P) 0,738 g 0,014 g 0,0001
V03AF09 Glucarpidase(P) 19000 U
V03AF10 Sodium levofolinate(P) 925 g 0,03 g 0,0636
V03AH Drugs for treatment of hypoglycemia
V03AH01 Diazoxide(O) 60 g
V03AN Medical gases
V03AN01 Oxygen(I) 486681000 ml
V03AN05 Air, medicinal(I) 2840000 ml
V04 DIAGNOSTIC AGENTS
V04C OTHER DIAGNOSTIC AGENTS
V04CD Tests for pituitary function
V04CD04 Corticorelin(P) 0,0004 g
V04CF Tuberculosis diagnostics
V04CF01 Tuberculin(P) 9630 U
V04CJ Tests for thyreoidea function
V04CJ02 Protirelin(P) 0,004 g
V04CX Other diagnostic agents
V04CX01 Indocyanine green(P) 1,15 g
V04CX03 Methacholine(I) 51,708 g
V04CX04 Mannitol(I) 14,605 g
V04CX04 Mannitol(I) 80 pieces
V04CX06 Hexaminolevulinate(P) 20,145 g
V04CX09 Patent blue(P) 5 g
V04CX87 Carbon monoxide+Helium(I) 20000 ml
V07 ALL OTHER NON-THERAPEUTIC PRODUCTS
V07A ALL OTHER NON-THERAPEUTIC PRODUCTS
V07AB Solvents and diluting agents, incl. irrigating solutions
V07AB80 Sodium chloride(P) 7065500 ml
V07AB83 Water for injection(NA) 16928200 ml
V08 CONTRAST MEDIA
V08A X-RAY CONTRAST MEDIA, IODINATED
V08AA Watersoluble, nephrotropic, high osmolar X-ray contrast media
V08AA01 Sodium amidotrizoate+Meglumine Amidotrizoate(P) 6000 ml
V08AB Watersoluble, nephrotropic, low osmolar X-ray contrast media
V08AB02 Iohexol(P) 1657574,5 g
V08AB05 Iopromide(P) 1186640 g
V08AB09 Iodixanol(P) 2849386 g
41/42
Estonian Statistics on Medicines 2020
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
V08AD Non-watersoluble X-ray contrast media
V08AD01 Ethyl esters of iodised fatty acids(P) 96 g
V08B X-RAY CONTRAST MEDIA, NON-IODINATED
V08BA Barium sulfate containing X-ray contrast media
V08BA01 Barium sulfate(O) 192520,72 g
V08C MAGNETIC RESONANCE IMAGING CONTRAST MEDIA
V08CA Paramagnetic contrast media
V08CA01 Gadopentetic acid(P) 4460 ml
V08CA02 Gadoteric acid(P) 54450 ml
V08CA09 Gadobutrol(P) 85447,5 ml
V08CA10 Gadoxetic acid(P) 5670 ml
V08D ULTRASOUND CONTRAST MEDIA
V08DA Ultrasound contrast media
V08DA05 Sulfur hexafluoride, phospholipid microspheres(P) 100 ml
V09 DIAGNOSTIC RADIOPHARMACEUTICALS
V09A CENTRAL NERVOUS SYSTEM
V09AB Iodine (123I) compounds
V09AB03 Ioflupane (123I)(P) 430 ml
V09F THYROID
V09FX Various thyroid diagnostic radiopharmaceuticals
V09FX01 Technetium (99mTc) pertechnetate(S) 30 pieces
V10 THERAPEUTIC RADIOPHARMACEUTICALS
V10X OTHER THERAPEUTIC RADIOPHARMACEUTICALS
V10XA Iodine (131I) compounds
V10XA01 Sodium iodide (131I)(O) 65 pieces
42/42
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A ALIMENTARY TRACT AND METABOLISM 188,4400
A01 STOMATOLOGICAL PREPARATIONS 0,0703
A01A STOMATOLOGICAL PREPARATIONS 0,0703
A01AB Antiinfectives and antiseptics for local oral treatment 0,0703
A01AB09 Miconazole (O) 6820,8 g 0,2 g 0,0703
A01AB12 Hexetidine (O) 1321280 ml
A01AB82 Demeclocycline+Triamcinolone (dental) 465 g
A01AD Other agents for local oral treatment
A01AD80 Lidocaine+Cetylpyridinium chloride (gingival) 221300 g
A01AD81 Lidocaine+Cetrimide (O) 64265 g
A01AD82 Choline salicylate (O) 403808 pieces
A01AD83 Lidocaine+Chamomille extract (O) 347870 g
A02 DRUGS FOR ACID RELATED DISORDERS 62,6277
A02A ANTACIDS 1,1306
A02AD Combinations and complexes of aluminium, calcium and
magnesium compounds 1,1306
A02AD81 Aluminium hydroxide+Magnesium hydroxide (O) 1227440 pieces 10 pieces 0,2528
A02AD81 Aluminium hydroxide+Magnesium hydroxide (O) 5263316 ml 50 ml 0,2168
A02AD83 Calcium carbonate+Magnesium carbonate (O) 3208344 pieces 10 pieces 0,6609
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-
OESOPHAGEAL REFLUX DISEASE (GORD) 61,4971
A02BA H2-receptor antagonists 0,0430
A02BA02 Ranitidine (P) 2757 g 0,3 g 0,0189
A02BA03 Famotidine (O) 468 g 0,04 g 0,0241
A02BC Proton pump inhibitors 61,4401
A02BC01 Omeprazole (O) 300792,74 g 0,02 g 30,9808
A02BC02 Pantoprazole (O) 320357,94 g 0,04 g 16,4980
A02BC02 Pantoprazole (P) 19,6 g 0,04 g 0,0010
A02BC03 Lansoprazole (O) 7,98 g 0,03 g 0,0005
A02BC04 Rabeprazole (O) 15,68 g 0,02 g 0,0016
A02BC05 Esomeprazole (O) 198885,96 g 0,03 g 13,6565
A02BC05 Esomeprazole (P) 4393,6 g 0,03 g 0,3017
A02BC08 Vonoprazan (O) 8 g
A02BD Combinations for eradication of Helicobacter pylori 0,0019
A02BD08 Bismuth subcitrate+Tetracycline+Metronidazole (O) 11160 pieces 12 pieces 0,0019
A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux
disease (GORD) 0,0120
A02BX02 Sucralfate (O) 23340 g 4 g 0,0120
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL
DISORDERS 8,8152
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL
DISORDERS 7,8830
A03AA Synthetic anticholinergics, esters with tertiary amino group 1,4006
A03AA04 Mebeverine (O) 203982 g 0,3 g 1,4006
A03AB Synthetic anticholinergics, quaternary ammonium compounds 0,0002
A03AB02 Glycopyrronium (P) 0,027 g 0,3 mg 0,0002
A03AD Papaverine and derivatives 4,8961
A03AD01 Papaverine hydrochloride (P) 20 g 0,1 g 0,0004
A03AD02 Drotaverine (O) 234638,08 g 0,1 g 4,8334
A03AD02 Drotaverine (P) 3022 g 0,1 g 0,0623
A03AX Other drugs for functional gastrointestinal disorders 1,5861
A03AX13 Simeticone (O) 384996,15 g 0,5 g 1,5861
A03B BELLADONNA AND DERIVATIVES, PLAIN 0,0744
A03BA Belladonna alkaloids, tertiary amines 0,0647
A03BA01 Atropine (O, P) 18,25 g 0,0015 g 0,0251
A03BA01 Atropine (P) 28,88 g 0,0015 g 0,0397
A03BB Belladonna alkaloids, semisynthetic, quaternary ammonium
compounds 0,0096
A03BB01 Hyoscine butylbromide (O) 1,8 g 0,06 g 0,0001
A03BB01 Hyoscine butylbromide (P) 278,8 g 0,06 g 0,0096
A03F PROPULSIVES 0,8578
1/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A03FA Propulsives 0,8578
A03FA01 Metoclopramide (O) 10650,5 g 0,03 g 0,7313
A03FA01 Metoclopramide (P) 1601,3 g 0,03 g 0,1100
A03FA03 Domperidone (O) 240,6 g 0,03 g 0,0165
A04 ANTIEMETICS AND ANTINAUSEANTS 0,1251
A04A ANTIEMETICS AND ANTINAUSEANTS 0,1251
A04AA Serotonin (5-HT3) antagonists 0,1169
A04AA01 Ondansetron (P) 192,36 g 0,016 g 0,0248
A04AA02 Granisetron (O) 63,73 g 0,002 g 0,0656
A04AA02 Granisetron (P) 35,5 g 0,003 g 0,0244
A04AA05 Palonosetron (P) 0,0025 g 0,25 mg <0,0001
A04AA80 Palonosetron+Netupitant (O) 1020 pieces 1 pieces 0,0021
A04AD Other antiemetics 0,0082
A04AD01 Scopolamine (TD) 5 pieces 1 pieces <0,0001
A04AD12 Aprepitant (O) 219,735 g 0,165 g 0,0027
A04AD81 Fosaprepitant (P) 251,7 g 0,095 g 0,0055
A05 BILE AND LIVER THERAPY 1,9950
A05A BILE THERAPY 0,5801
A05AA Bile acids and derivatives 0,5801
A05AA02 Ursodeoxycholic acid (O) 211225 g 0,75 g 0,5801
A05B LIVER THERAPY, LIPOTROPICS 1,4149
A05BA Liver therapy 1,4149
A05BA03 Silymarin (O) 1955410 pieces
A05BA03 Silymarin (P) 56 g
A05BA80 Phospholipids from Soya Beans (O) 1368450 pieces 3 pieces 0,9396
A05BA80 Phospholipids from Soya Beans (O) 1384250 pieces 6 pieces 0,4752
A05BA80 Phospholipids from Soya Beans (P) 605 pieces
A06 DRUGS FOR CONSTIPATION 17,4337
A06A DRUGS FOR CONSTIPATION 17,4337
A06AB Contact laxatives 7,6130
A06AB02 Bisacodyl (O) 14106,4 g 0,01 g 2,9058
A06AB02 Bisacodyl (R) 160,82 g 0,01 g 0,0331
A06AB06 Senna glycosides (O) 2480 pieces 1 pieces 0,0051
A06AB08 Sodium picosulfate (O) 11324,937 g 0,005 g 4,6657
A06AB80 Sodium picosulfate+Magnesium oxide+Citric acid (O) 3080 pieces 2 pieces 0,0032
A06AD Osmotically acting laxatives 8,7400
A06AD11 Lactulose (O) 26717524,2 g 6,7 g 8,2144
A06AD15 Macrogol (O) 2551560 g 10 g 0,5256
A06AD80 Macrogol+Sodium citrate+Citric acid+Sodium
chloride+Potassium chloride (O) 17000 ml
A06AD81 Sodium sulphate, anhydrous+Potassium chloride+Sodium
chloride+Macrogol+Sodium hydrogen carbonate (O) 32936 pieces
A06AD83
Macrogol+Sodium sulphate, anhydrous+Sodium
chloride+Potassium chloride+Ascorbic acid+Sodium ascorbate
(O)
6412 pieces
A06AD85 Sodium sulphate, anhydrous+magnesium sulfate
heptahydrate+Potassium sulphate (O) 720896 ml
A06AG Enemas 1,0292
A06AG11 Laurilsulfate, incl. combinations+Sorbitol+Sodium citrate (R) 499608 pieces 1 pieces 1,0292
A06AH Peripheral opioid receptor antagonists 0,0515
A06AH03 Naloxegol (O) 624,75 g 25 mg 0,0515
A06AX Other drugs for constipation
A06AX81 Sodium hydrogen carbonate+Potassium hydrogentartrate (R) 120 pieces
A07 ANTIDIARRHEALS, INTESTINAL
ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS 4,3086
A07A INTESTINAL ANTIINFECTIVES 0,0054
A07AA Antibiotics 0,0054
A07AA02 Nystatin (O) 100000000 U 1500000 U 0,0001
A07AA11 Rifaximin (O) 1536 g 0,6 g 0,0053
A07B INTESTINAL ADSORBENTS 0,3805
A07BC Other intestinal adsorbents 0,3805
A07BC05 Diosmectidum (O) 1662420 g 9 g 0,3805
2/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A07C ELECTROLYTES WITH CARBOHYDRATES
A07CA Oral rehydration salt formulations
A07CA80 Sodium chloride+Potassium chloride+Sodium citrate+Glucose
(O) 86920 pieces
A07D ANTIPROPULSIVES 0,9125
A07DA Antipropulsives 0,9125
A07DA03 Loperamide (O) 4429,652 g 0,01 g 0,9125
A07E INTESTINAL ANTIINFLAMMATORY AGENTS 2,4140
A07EA Corticosteroids acting locally 0,0271
A07EA06 Budesonide (O) 118,29 g 0,009 g 0,0271
A07EA06 Budesonide (R) 1,5694 g
A07EC Aminosalicylic acid and similar agents 2,3869
A07EC01 Sulfasalazine (O) 757500 g 2 g 0,7802
A07EC02 Mesalazine (O) 1072408 g 1,5 g 1,4727
A07EC02 Mesalazine (R) 97544 g 1,5 g 0,1340
A07F ANTIDIARRHEAL MICROORGANISMS 0,5962
A07FA Antidiarrheal microorganisms 0,5962
A07FA02 Saccharomyces boulardii (O) 289442,5 g 1 g 0,5962
A07X OTHER ANTIDIARRHEALS
A07XA Other antidiarrheals
A07XA04 Racecadotril (O) 2869,44 g
A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0503
A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0503
A08AA Centrally acting antiobesity products 0,0503
A08AA62 Bupropione+Naltrexone (O) 97664 pieces 4 pieces 0,0503
A09 DIGESTIVES, INCL. ENZYMES 1,8176
A09A DIGESTIVES, INCL. ENZYMES 1,8176
A09AA Enzyme preparations 1,8176
A09AA02 Lipase+Amylase+Protease (O) 3529492 pieces 4 pieces 1,8176
A10 DRUGS USED IN DIABETES 67,4826
A10A INSULINS AND ANALOGUES 15,3462
A10AB Insulins and analogues for injection, fast-acting 5,8915
A10AB01 Insulin (human) (P) 1339500 U 40 U 0,0690
A10AB04 Insulin lispro (P) 19329000 U 40 U 0,9954
A10AB05 Insulin aspart (P) 82717500 U 40 U 4,2598
A10AB06 Insulin glulisine (P) 11014500 U 40 U 0,5672
A10AC Insulins and analogues for injection, intermediate-acting 0,0485
A10AC01 Insulin (human) (P) 942000 U 40 U 0,0485
A10AD Insulins and analogues for injection, intermediate- or long-
acting combined with fast-acting 0,6543
A10AD04 Insulin lispro (P) 3465000 U 40 U 0,1784
A10AD05 Insulin aspart (P) 8764500 U 40 U 0,4514
A10AD06 Insulin degludec+Insulin aspart (P) 476000 U 40 U 0,0245
A10AE Insulins and analogues for injection, long-acting 8,7519
A10AE04 Insulin glargine (P) 91207500 U 40 U 4,6971
A10AE05 Insulin detemir (P) 33979500 U 40 U 1,7499
A10AE06 Insulin degludec (P) 41344200 U 40 U 2,1292
A10AE54 Insulin glargine+Lixisenatide (P) 3412500 U 40 U 0,1757
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS 52,1365
A10BA Biguanides 20,9501
A10BA02 Metformin (O) 20340486 g 2 g 20,9501
A10BB Sulfonylureas 11,2810
A10BB07 Glipizide (O) 767,1 g 0,01 g 0,1580
A10BB09 Gliclazide (O) 187531,8 g 0,06 g 6,4384
A10BB12 Glimepiride (O) 4548,27 g 0,002 g 4,6846
A10BD Combinations of oral blood glucose lowering drugs 7,9925
A10BD07 Metformin+Sitagliptin (O) 1512000 pieces 2 pieces 1,5573
A10BD08 Metformin+Vildagliptin (O) 1347660 pieces 2 pieces 1,3881
A10BD10 Metformin+Saxagliptin (O) 291720 pieces 2 pieces 0,3005
A10BD11 Metformin+Linagliptin (O) 1280520 pieces 2 pieces 1,3189
A10BD15 Metformin+Dapagliflozin (O) 1014944 pieces 2 pieces 1,0454
3/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A10BD19 Linagliptin+Empagliflozin (O) 217080 pieces 1 pieces 0,4472
A10BD20 Metformin+Empagliflozin (O) 1681260 pieces 2 pieces 1,7317
A10BD21 Saxagliptin+Dapagliflozin (O) 97944 pieces 1 pieces 0,2018
A10BD23 Metformin+Ertugliflozin (O) 896 pieces 1 pieces 0,0018
A10BF Alpha glucosidase inhibitors 0,0006
A10BF01 Acarbose (O) 89,25 g 0,3 g 0,0006
A10BG Thiazolidinediones 0,1295
A10BG03 Pioglitazone (O) 1886,22 g 0,03 g 0,1295
A10BH Dipeptyl peptidase 4 (DPP-4) inhibitors 4,1812
A10BH01 Sitagliptin (O) 39196,5 g 0,1 g 0,8074
A10BH02 Vildagliptin (O) 7593 g 0,1 g 0,1564
A10BH03 Saxagliptin (O) 504,9 g 5 mg 0,2080
A10BH05 Linagliptin (O) 7304,55 g 5 mg 3,0094
A10BJ Glucagon-like peptide-1 (GLP-1) analogues 4,1123
A10BJ01 Exenatide (P) 4,368 g 0,286 mg 0,0315
A10BJ02 Liraglutide (P) 482,796 g 1,5 mg 0,6630
A10BJ03 Lixisenatide (P) 0,3993 g 20 mcg 0,0411
A10BJ05 Dulaglutide (P) 34,104 g 0,16 mg 0,4391
A10BJ06 Semaglutide (O) 576,63 g 10,5 mg 0,1131
A10BJ06 Semaglutide (P) 150,827 g 0,11 mg 2,8245
A10BK Sodium-glucose co-transporter 2 (SGLT2) inhibitors 3,4891
A10BK01 Dapagliflozin (O) 7520,4 g 10 mg 1,5492
A10BK03 empagliflozin (O) 16477,05 g 17,5 mg 1,9395
A10BK04 Ertugliflozin (O) 1,96 g 10 mg 0,0004
A11 VITAMINS 14,0734
A11A MULTIVITAMINS, COMBINATIONS 1,3133
A11AA Multivitamins with minerals 1,3133
A11AA03 Multivitamins+Mineral elements (O) 637560 pieces 1 pieces 1,3133
A11C VITAMIN A AND D, INCL. COMBINATIONS OF THE TWO 5,3526
A11CA Vitamin A, plain <0,0001
A11CA01 Retinol (P) 600000 U 50000 U <0,0001
A11CC Vitamin D and analogues 5,3526
A11CC04 Calcitriol (O) 0,1299 g 0,001 mg 0,2676
A11CC05 Colecalciferol (O) 987400000 U 400 U 5,0850
A11CC05 Colecalciferol (P) 31000000 U
A11D VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN
B6 AND B12 1,5294
A11DA Vitamin B1, plain 0,4082
A11DA01 Thiamine (P) 9908,5 g 0,05 g 0,4082
A11DA03 Benfotiamine (O) 1689370 pieces
A11DB Vitamin B1 in combination with vitamin B6 and/or vitamin B12 1,1212
A11DB80 Thiamine+Pyridoxine (P) 3750 pieces 1 pieces 0,0077
A11DB81 Benfotiamine+Pyridoxine (O) 227520 pieces 3 pieces 0,1562
A11DB84 Thiamine+Pyridoxine+Cyanocobalamin (O) 401120 pieces 1 pieces 0,8263
A11DB85 Thiamine+Pyridoxine+Cyanocobalamin+Lidocaine (P) 63590 pieces 1 pieces 0,1310
A11E VITAMIN B-COMPLEX, INCL. COMBINATIONS 0,4707
A11EA Vitamin B-complex, plain 0,4707
A11EA80 Thiamine+Nicotinamide+Riboflavin+Calcium
pantothenate+Pyridoxine (O) 228500 pieces 1 pieces 0,4707
A11EA80 Thiamine+Nicotinamide+Riboflavin+Calcium
pantothenate+Pyridoxine (P) 1032 pieces
A11G ASCORBIC ACID (VITAMIN C), INCL. COMBINATIONS 0,1610
A11GA Ascorbic acid (vitamin C), plain 0,1610
A11GA01 Ascorbic acid (P) 15630 g 0,2 g 0,1610
A11H OTHER PLAIN VITAMIN PREPARATIONS 0,0511
A11HA Other plain vitamin preparations 0,0511
A11HA02 Pyridoxine (O) 150 g 0,16 g 0,0019
A11HA02 Pyridoxine (P) 3630,5 g 0,16 g 0,0467
A11HA03 Tocopherol (P) 4,5 g 0,2 g <0,0001
A11HA08 Tocofersolan (O) 234 g 0,2 g 0,0024
A11J OTHER VITAMIN PRODUCTS, COMBINATIONS 5,1952
A11JA Combinations of vitamins
4/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
A11JA80 Combinations of vitamins (O) 700 ml
A11JB Vitamins with minerals 5,1952
A11JB81 Pyridoxine+Magnesium (O) 7469180 pieces 4 pieces 3,8465
A11JB82
Thiamine+Riboflavin+Pyridoxine+Cyanocobalamin+Ascorbic
acid+Biotin+Nicotinamide+Calcium
pantothenate+Calcium+Magnesium+Folic acid+Zinc (O)
654735 pieces 1 pieces 1,3487
A12 MINERAL SUPPLEMENTS 8,9740
A12A CALCIUM 5,4367
A12AA Calcium 0,9393
A12AA03 Calcium gluconate (P) 60410 g 3 g 0,0415
A12AA04 Calcium carbonate (O) 1307550 g 3 g 0,8978
A12AX Calcium, combinations with vitamin D and/or other drugs 4,4974
A12AX80 Calcium+Colecalciferol (O) 611880 pieces 1 pieces 1,2604
A12AX80 Calcium+Colecalciferol (O) 3142740 pieces 2 pieces 3,2369
A12B POTASSIUM 3,0981
A12BA Potassium 3,0981
A12BA01 Potassium chloride (O) 380400 g 3 g 0,2612
A12BA80 Potassium chloride+Potassium hydrogen carbonate (O) 10600 pieces
A12BA81 Potassium aspartate+Magnesium aspartate (O) 4094050 pieces 3 pieces 2,8112
A12BA81 Potassium aspartate+Magnesium aspartate (P) 12490 pieces 1 pieces 0,0257
A12C OTHER MINERAL SUPPLEMENTS 0,4392
A12CC Magnesium 0,4392
A12CC04 Magnesium citrate (O) 426425,192 g 2 g 0,4392
A12CX Other mineral products
A12CX83 Phosphate (O) 12200 pieces
A14 ANABOLIC AGENTS FOR SYSTEMIC USE 0,0025
A14A ANABOLIC STEROIDS 0,0025
A14AB Estren derivatives 0,0025
A14AB01 Nandrolone (P) 2,4 g 0,002 g 0,0025
A16 OTHER ALIMENTARY TRACT AND METABOLISM
PRODUCTS 0,6640
A16A OTHER ALIMENTARY TRACT AND METABOLISM
PRODUCTS 0,6640
A16AA Amino acids and derivatives 0,0021
A16AA01 Levocarnitine (O) 2070 g 2 g 0,0021
A16AA02 Ademetionine (O) 900 g
A16AA02 Ademetionine (P) 50 g
A16AA81 Glycine (O) 390 g
A16AB Enzymes 0,0046
A16AB03 Agalsidase alfa (P) 1,337 g 0,001 g 0,0028
A16AB04 Agalsidase beta (P) 1,625 g 0,005 g 0,0007
A16AB07 Alglucosidase alfa (P) 57,5 g 0,1 g 0,0012
A16AB09 Idursulfase (P) 1,344 g
A16AX Various alimentary tract and metabolism products 0,6573
A16AX01 Thioctic acid (O) 187506 g 0,6 g 0,6438
A16AX01 Thioctic acid (P) 342 g 0,6 g 0,0012
A16AX03 Sodium phenylbutyrate (O) 1250 g 20 g 0,0001
A16AX05 Zinc (O) 700 g 0,15 g 0,0096
A16AX07 Sapropterin (O) 876 g
A16AX10 Eliglustat (O) 211,68 g 0,168 g 0,0026
A16AX80 Creatine (O) 450 g
A16AX81 Copper histidine (P) 0,2 g
B BLOOD AND BLOOD FORMING ORGANS 112,5103
B01 ANTITHROMBOTIC AGENTS 83,6039
B01A ANTITHROMBOTIC AGENTS 83,6039
B01AA Vitamin K antagonists 1,5288
B01AA03 Warfarin (O) 5566,1 g 0,0075 g 1,5288
B01AB Heparin group 3,4423
B01AB01 Heparin sodium (P) 591625000 U 10000 U 0,1219
B01AB05 Enoxaparin sodium (hem, P) 1151800000 U 2000 U 1,1863
B01AB05 Enoxaparin sodium (P) 1746104000 U 2000 U 1,7984
B01AB06 Nadroparin calcium (P) 2413000 U 2850 U 0,0017
5/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B01AB12 Bemiparin sodium (P) 405245000 U 2500 U 0,3339
B01AC Platelet aggregation inhibitors, excl. heparin 54,5428
B01AC04 Clopidogrel (O) 146263,8 g 0,075 g 4,0173
B01AC06 Acetylsalicylic acid (O) 4712830 pieces 1 pieces 9,7082
B01AC09 Epoprostenol (P) 0,001 g
B01AC11 Iloprost (I) 0,0437 g 0,15 mg 0,0006
B01AC11 Iloprost (P) 0,0045 g 50 mcg 0,0002
B01AC16 Eptifibatide (P) 64,365 g 0,2 g 0,0007
B01AC21 Treprostinil (P) 1,88 g 0,0043 g 0,0009
B01AC24 Ticagrelor (O) 102275,04 g 0,18 g 1,1704
B01AC27 Selexipag
(O) 3,672 g 1,8 mg 0,0042
B01AC80 Acetylsalicylic acid +Magnesium oxide (O) 19243400 pieces 1 pieces 39,6403
B01AD Enzymes 0,0023
B01AD02 Alteplase (P) 97,47 g 0,1 g 0,0020
B01AD11 Tenecteplase (P) 6,25 g 0,04 g 0,0003
B01AE Direct thrombin inhibitors 2,6545
B01AE03 Argatroban (P) 1,5 g 0,2 g <0,0001
B01AE06 Bivalirudine (P) 2,5 g 0,25 g <0,0001
B01AE07 Dabigatran etexilate (O) 386586,75 g 0,3 g 2,6545
B01AF Direct factor Xa inhibitors 21,4316
B01AF01 Rivaroxaban (O) 103850,7934 g 0,02 g 10,6963
B01AF02 Apixaban (O) 47447,55 g 10 mg 9,7739
B01AF03 Edoxaban (O) 28000,8 g 60 mg 0,9613
B01AX Other antithrombotic agents 0,0016
B01AX05 Fondaparinux sodium (P) 1,95 g 0,0025 g 0,0016
B02 ANTIHEMORRHAGICS 0,1892
B02A ANTIFIBRINOLYTICS 0,1625
B02AA Amino acids 0,1625
B02AA01 Aminocaproic acid (P) 6175 g 16 g 0,0008
B02AA02 Tranexamic acid (O) 120180 g 2 g 0,1238
B02AA02 Tranexamic acid (P) 36867,5 g 2 g 0,0380
B02B VITAMIN K AND OTHER HEMOSTATICS 0,0266
B02BA Vitamin K 0,0042
B02BA01 Phytomenadione (O) 7,5 g 0,02 g 0,0008
B02BA01 Phytomenadione (O, P) 8,03 g 0,02 g 0,0008
B02BA01 Phytomenadione (P) 25,35 g 0,02 g 0,0026
B02BB Fibrinogen 0,0001
B02BB01 Fibrinogen human (P) 345 g 5 g 0,0001
B02BC Local hemostatics
B02BC81 Fibrinogen human+Human thrombin (epil) 631 pieces
B02BD Blood coagulation factors
B02BD01 Human prothrombin complex (P) 251200 U
B02BD02 Human coagulation factor VIII (P) 3024500 U
B02BD04 Human coagulation factor IX (P) 685600 U
B02BD05 Human coagulation factor VII (P) 180000 U
B02BD06 Von Willebrand factor, human+Human coagulation factor VIII
(P) 1625250 U
B02BD08 Coagulation factor VIIa (P) 14150000 U
B02BD80 Turoctocog alfa (P) 4000 U
B02BD81 Simoctocog alfa (P) 143000 U
B02BD83 Efmoroctocog alfa (P) 3837000 U
B02BX Other systemic hemostatics 0,0223
B02BX01 Etamsylate (P) 567,5 g
B02BX04 Romiplostim (P) 0,0735 g 30 mcg 0,0050
B02BX05 Eltrombopag (O) 310,1 g 50 mg 0,0128
B02BX06 Emicizumab (P) 32,46 g 15 mg 0,0045
B03 ANTIANEMIC PREPARATIONS 28,7143
B03A IRON PREPARATIONS 4,3963
B03AA Iron bivalent, oral preparations 2,4065
B03AA07 Ferrous sulphate (O) 233643 g 0,2 g 2,4065
B03AB Iron trivalent, oral preparations
6/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B03AB80 Iron (III)-hydroxide polymaltose complex (O) 81936 g
B03AC Iron, parenteral preparations 0,1149
B03AC01 Dextriferron (P) 2053,5 g 0,1 g 0,0423
B03AC02 Iron (III)-hydroxide sucrose complex (P) 1472 g 0,1 g 0,0303
B03AC06 Iron (III)-hydroxide dextran complex (P) 1000 g 0,1 g 0,0206
B03AC80 Ferric derisomaltose (P) 1054,5 g 0,1 g 0,0217
B03AD Iron in combination with folic acid 1,8749
B03AD02 Ferrous fumarate+Folic acid (O) 509090 pieces 1 pieces 1,0487
B03AD03 Ferrous sulphate+Folic acid (O) 401100 pieces 1 pieces 0,8262
B03AE Iron in other combinations
B03AE81 Ferrous gluconate+Manganese gluconate+Copper gluconate
(O) 1653600 ml
B03AE82 Ferrous fumarate+Folic acid+Ascorbic acid (O) 35690 pieces
B03B VITAMIN B12 AND FOLIC ACID 23,3333
B03BA Vitamin B12 (cyanocobalamin and analogues) 6,5782
B03BA01 Cyanocobalamin (O) 10,3 g 1 mg 0,0212
B03BA01 Cyanocobalamin (P) 62,86 g 0,02 mg 6,4744
B03BA03 Hydroxocobalamin (P) 0,802 g 0,02 mg 0,0826
B03BB Folic acid and derivatives 16,7551
B03BB01 Folic acid (O) 3253,5 g 0,4 mg 16,7551
B03X OTHER ANTIANEMIC PREPARATIONS 0,9847
B03XA Other antianemic preparations 0,9847
B03XA02 Darbepoetin alfa (P) 1,5333 g 0,0045 mg 0,7019
B03XA03 Methoxy polyethylene glycol-epoetin beta (P) 0,3039 g 4 mcg 0,1565
B03XA80 Epoetin beta (P) 61302000 U 1000 U 0,1263
B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B05A BLOOD AND RELATED PRODUCTS
B05AA Blood substitutes and plasma protein fractions
B05AA01 Albumin (P) 913255 g
B05AA06 Gelatin agents (P) 6045000 ml
B05AA83 Gelatine+Sodium chloride+Potassium chloride+Magnesium
chloride+Sodium lactate (P) 550000 ml
B05AA86 human plasma proteins (P) 537800 ml
B05B I.V. SOLUTIONS
B05BA Solutions for parenteral nutrition
B05BA01 Amino acids (P) 1084000 ml
B05BA02 Fat emulsions (P) 107000 ml
B05BA03 Carbohydrates (P) 61720 g
B05BA03 Carbohydrates (P) 68538600 ml
B05BA10 Combinations (P) 17379915 ml
B05BB Solutions affecting the electrolyte balance
B05BB01 Electrolytes (P) 289763500 ml
B05BC Solutions producing osmotic diuresis
B05BC01 Mannitol (P) 1056000 ml
B05C IRRIGATING SOLUTIONS
B05CX Other irrigating solutions
B05CX10 Combinations (NA) 100000 ml
B05D PERITONEAL DIALYTICS
B05DA Isotonic solutions
B05DA80 Isotonic solutions (P) 10400000 ml
B05DB Hypertonic solutions
B05DB80 hypertonic solutions (P) 156132000 ml
B05DB81
Amino acids+Sodium chloride+Calcium chloride
dihydrate+Magnesium chloride hexahydrate+Sodium lactate
(P)
850000 ml
B05Z HEMODIALYTICS AND HEMOFILTRATES
B05ZB Hemofiltrates
B05ZB80
Sodium chloride+Potassium chloride+Calcium chloride
dihydrate+Magnesium chloride+Glucose+Sodium hydrogen
carbonate (P)
33840000 ml
7/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
B05ZB82
Calcium chloride dihydrate+Magnesium chloride
hexahydrate+Sodium chloride+Sodium hydrogen
carbonate+Potassium chloride+Disodium phosphate dihydrate
(P)
10010000 ml
B05ZB83
Calcium chloride dihydrate+Magnesium chloride
hexahydrate+Glucose+Lactic acid+Sodium chloride+Sodium
hydrogen carbonate+Potassium chloride (P)
200000 ml
B05ZB84
Calcium chloride dihydrate+Magnesium chloride
hexahydrate+Lactic acid+Sodium hydrogen
carbonate+Sodium chloride (P)
950000 ml
B05ZB85 Sodium citrate+Sodium chloride (P) 28460000 ml
B05ZB86
Magnesium chloride hexahydrate+Sodium chloride+Potassium
chloride+Disodium phosphate dihydrate+Sodium hydrogen
carbonate (P)
12950000 ml
B05X I.V. SOLUTION ADDITIVES
B05XA Electrolyte solutions
B05XA01 Potassium chloride (P) 750 g
B05XA01 Potassium chloride (P) 3453200 ml
B05XA02 Sodium hydrogen carbonate (P) 1476500 ml
B05XA03 Sodium chloride (P) 9 g
B05XA03 Sodium chloride (P) 361069780 ml
B05XA05 Magnesium sulphate (P) 425000 ml
B05XA07 Calcium chloride (P) 418700 ml
B05XA14 Sodium glycerophosphate, hydrated (P) 133000 ml
B05XA80 Electrolytes (P) 147600 ml
B05XB Amino acids
B05XB01 Arginine (P) 4500 ml
B05XB02 Alanyl glutamine (P) 62000 ml
B05XC Vitamins
B05XC80 Vitamins (P) 8220,24 g
B05XC80 Vitamins (P) 125400 ml
B06 OTHER HEMATOLOGICAL AGENTS 0,0029
B06A OTHER HEMATOLOGICAL AGENTS 0,0029
B06AA Enzymes
B06AA03 Hyaluronidase (P) 90000 U
B06AB Heme products
B06AB81 Hemin (P) 40 ml
B06AC Drugs usedin hereditary angioedema 0,0029
B06AC01 C1-inhibitor, plasma derived (P) 315000 U 1400 U 0,0005
B06AC02 Icatibant (P) 6,15 g 0,03 g 0,0004
B06AC05 Lanadelumab (P) 20,7 g 21,4 mg 0,0020
C CARDIOVASCULAR SYSTEM 449,7935
C01 CARDIAC THERAPY 20,7126
C01A CARDIAC GLYCOSIDES 2,0111
C01AA Digitalis glycosides 2,0111
C01AA05 Digoxin (O) 242,1925 g 0,25 mg 1,9956
C01AA05 Digoxin (P) 1,85 g 0,25 mg 0,0152
C01AA06 Lanatoside C (O) 0,105 g 0,001 g 0,0002
C01B ANTIARRHYTHMICS, CLASS I AND III 4,9697
C01BA Antiarrhythmics, class Ia
C01BA13 Hydroquinidine (O) 324 g
C01BB Antiarrhythmics, class Ib 0,0192
C01BB02 Mexiletine (O) 160 g 0,8 g 0,0004
C01BB80 Aethacizin (O) 1822,5 g 0,2 g 0,0188
C01BC Antiarrhythmics, class Ic 3,3101
C01BC03 Propafenone (O) 458685 g 0,3 g 3,1496
C01BC03 Propafenone (P) 359,1 g 0,3 g 0,0025
C01BC04 Flecainide (O) 15326 g 0,2 g 0,1579
C01BC04 Flecainide (P) 18,75 g 0,2 g 0,0002
C01BD Antiarrhythmics, class III 1,6405
C01BD01 Amiodarone (O) 152766 g 0,2 g 1,5734
C01BD01 Amiodarone (P) 5427 g 0,2 g 0,0559
8/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C01BD07 Dronedarone (O) 4320 g 0,8 g 0,0111
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES 0,6722
C01CA Adrenergic and dopaminergic agents 0,6705
C01CA01 Etilefrine (O) 2,0625 g 0,05 g 0,0001
C01CA02 Isoprenaline (P) 0,657 g 0,09 g <0,0001
C01CA03 Norepinephrine (P) 396,04 g 0,006 g 0,1360
C01CA04 Dopamine (P) 622 g 0,5 g 0,0026
C01CA06 Phenylephrine (P) 118 g 0,004 g 0,0608
C01CA07 Dobutamine (P) 837,5 g 0,5 g 0,0035
C01CA17 Midodrine (O) 10,95 g 0,03 g 0,0008
C01CA24 Epinephrine (intraoss, P) 44,56 g 0,5 mg 0,1836
C01CA24 Epinephrine (P) 57,694 g 0,5 mg 0,2377
C01CA26 Ephedrine (P) 1108,25 g 0,05 g 0,0457
C01CE Phosphodiesterase inhibitors 0,0012
C01CE02 Milrinone (P) 28,06 g 0,05 g 0,0012
C01CX Other cardiac stimulants 0,0005
C01CX08 Levosimendan (P) 2,9 g 11 mg 0,0005
C01CX80 Ammonia (I) 1450280 ml
C01D VASODILATORS USED IN CARDIAC DISEASES 5,3544
C01DA Organic nitrates 5,3527
C01DA02 Glyceryl trinitrate (P) 172,1 g
C01DA02 Glyceryl trinitrate (SL) 496,752 g 0,0025 g 0,4093
C01DA05 Pentaerithrityl tetranitrate (O) 3 g 0,12 g 0,0001
C01DA08 Isosorbide dinitrate (O) 22,5 g 0,06 g 0,0008
C01DA08 Isosorbide dinitrate (SL) 261,975 g 0,02 g 0,0270
C01DA14 Isosorbide mononitrate (O) 95450,2 g 0,04 g 4,9156
C01DX Other vasodilatators used in cardiac diseases 0,0018
C01DX80 Meldonium (O) 615 g 0,75 g 0,0017
C01DX80 Meldonium (P) 25 g 0,75 g 0,0001
C01E OTHER CARDIAC PREPARATIONS 7,7052
C01EA Prostaglandins 0,0002
C01EA01 Alprostadil (P) 0,0448 g 0,5 mg 0,0002
C01EB Other cardiac preparations 7,7050
C01EB10 Adenosine (P) 119,192 g 0,015 g 0,0164
C01EB15 Trimetazidine (O) 140036,4 g 0,04 g 7,2117
C01EB16 Ibuprofen (P) 0,4 g 0,03 g <0,0001
C01EB17 Ivabradine (O) 1847,58 g 0,01 g 0,3806
C01EB18 Ranolazine (O) 69427,5 g 1,5 g 0,0953
C01EB21 Regadenoson (P) 0,188 g 0,4 mg 0,0010
C01EB80 Hawthorn berry (O) 31040 ml
C02 ANTIHYPERTENSIVES 3,7403
C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING 2,3417
C02AC Imidazoline receptor agonists 2,3417
C02AC01 Clonidine (O) 5,025 g 0,45 mg 0,0230
C02AC01 Clonidine (P) 2,829 g 0,45 mg 0,0130
C02AC02 Guanfacine (O) 0,196 g 3 mg 0,0001
C02AC05 Moxonidine (O) 335,783 g 0,3 mg 2,3056
C02C ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING 1,3603
C02CA Alpha-adrenoreceptor antagonists 1,3603
C02CA01 Prazosin (O) 1,62 g 0,005 g 0,0007
C02CA04 Doxazosin (O) 2640,116 g 0,004 g 1,3596
C02D ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON 0,0006
C02DD Nitroferricyanide derivatives 0,0006
C02DD01 Sodium nitroprusside (P) 14,25 g 0,05 g 0,0006
C02K OTHER ANTIHYPERTENSIVES 0,0377
C02KX Antihypertensives for pulmonary arterial hypertension 0,0377
C02KX01 Bosentan (O) 1368,5 g 0,25 g 0,0113
C02KX02 Ambrisentan (O) 49,95 g 7,5 mg 0,0137
C02KX04 Macitentan (O) 4,8 g 10 mg 0,0010
C02KX05 Riociguat (O) 25,494 g 4,5 mg 0,0117
C03 DIURETICS 26,3879
C03A LOW-CEILING DIURETICS, THIAZIDES 1,2035
9/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C03AA Thiazides, plain 1,2035
C03AA03 Hydrochlorothiazide (O) 14605,5 g 0,025 g 1,2035
C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES 2,1909
C03BA Sulfonamides, plain 2,1909
C03BA11 Indapamide (O) 2658,9 g 2,5 mg 2,1909
C03C HIGH-CEILING DIURETICS 19,5433
C03CA Sulfonamides, plain 19,5433
C03CA01 Furosemide (O) 62122,6 g 0,04 g 3,1992
C03CA01 Furosemide (P) 4993 g 0,04 g 0,2571
C03CA04 Torasemide (O) 116733 g 0,015 g 16,0309
C03CA04 Torasemide (P) 407,8 g 0,015 g 0,0560
C03D ALDOSTERONE ANTAGONISTS AND OTHER POTASSIUM-
SPARING AGENTS 3,4324
C03DA Aldosterone antagonists 3,4324
C03DA01 Spironolactone (O) 124934,25 g 0,075 g 3,4314
C03DA04 Eplerenone (O) 23,25 g 0,05 g 0,0010
C03E DIURETICS AND POTASSIUM-SPARING AGENTS IN
COMBINATION 0,0179
C03EA Low-ceiling diuretics and potassium-sparing agents 0,0179
C03EA81 Hydrochlorothiazide+Amiloride (O) 8700 pieces 1 pieces 0,0179
C04 PERIPHERAL VASODILATORS 2,5427
C04A PERIPHERAL VASODILATORS 2,5427
C04AC Nicotinic acid and derivatives 0,0004
C04AC01 Nicotinic acid (P) 38 g 0,2 g 0,0004
C04AD Purine derivatives 1,4605
C04AD02 Xantinol nicotinate (O) 54 g 0,9 g 0,0001
C04AD03 Pentoxifylline (O) 707552 g 1 g 1,4575
C04AD03 Pentoxifylline (P) 418 g 0,3 g 0,0029
C04AX Other peripheral vasodilators 1,0818
C04AX21 Naftidrofuryl (O) 315090 g 0,6 g 1,0818
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL
FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA82 Hydrocortisone+Cinchocaine (R) 13788 pieces
C05AA84 Fluocortolone+Lidocaine (R) 215700 g
C05AA84 Fluocortolone+Lidocaine (R) 272520 pieces
C05AX Other agents for treatment of hemorrhoids and anal fissures
for topical use
C05AX81 Xeroformium+Zinc sulphate+Extract of Belladonna (R) 2880 pieces
C05AX83 Yeast cell extract+Shark liver oil (R) 265440 pieces
C05B ANTIVARICOSE THERAPY
C05BA Heparins or heparinoids for topical use
C05BA03 Heparin sodium (C) 7546000 g
C05BB Sclerosing agents for local injection
C05BB02 Lauromacrogol 400 (P) 81,375 g
C05C CAPILLARY STABILIZING AGENTS
C05CA Bioflavonoids
C05CA01 Rutoside (O) 216750 pieces
C05CA03 Diosmin (O) 510690 g
C05CA04 Troxerutin (C) 3559740 g
C05CA04 Troxerutin (O) 202395 g
C05CA53 Diosmin+Hesperidine (O) 2220 pieces
C05CA53 Diosmin+Hesperidine (O) 42619,5 g
C07 BETA BLOCKING AGENTS 57,0059
C07A BETA BLOCKING AGENTS 57,0054
C07AA Beta blocking agents, non-selective 1,5725
C07AA05 Propranolol (O) 50817,5 g 0,16 g 0,6543
C07AA07 Sotalol (O) 71325,6 g 0,16 g 0,9183
C07AB Beta blocking agents, selective 54,8343
C07AB02 Metoprolol (O) 1975176,05 g 0,15 g 27,1250
C07AB02 Metoprolol (P) 111,725 g 0,15 g 0,0015
10/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C07AB03 Atenolol (O) 16983,75 g 0,075 g 0,4665
C07AB07 Bisoprolol (O) 18936,45 g 0,01 g 3,9008
C07AB12 Nebivolol (O) 56653,14 g 0,005 g 23,3405
C07AG Alpha and beta blocking agents 0,5985
C07AG01 Labetalol (O) 31350 g 0,6 g 0,1076
C07AG01 Labetalol (P) 1484 g 0,6 g 0,0051
C07AG02 Carvedilol (O) 8843,8125 g 0,0375 g 0,4858
C07B BETA BLOCKING AGENTS AND THIAZIDES 0,0005
C07BB Beta blocking agents, selective, and thiazides 0,0005
C07BB07 Bisoprolol+Hydrochlorothiazide (O) 240 pieces 1 pieces 0,0005
C08 CALCIUM CHANNEL BLOCKERS 44,0099
C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH
MAINLY VASCULAR EFFECTS 42,6730
C08CA Dihydropyridine derivatives 42,6730
C08CA01 Amlodipine (O) 62464,8 g 0,005 g 25,7348
C08CA02 Felodipine (O) 5197,275 g 0,005 g 2,1412
C08CA05 Nifedipine (O) 13717,76 g 0,03 g 0,9419
C08CA06 Nimodipine (O) 351 g 0,3 g 0,0024
C08CA06 Nimodipine (P) 3,42 g 0,05 g 0,0001
C08CA08 Nitrendipine (O) 38023,12 g 0,02 g 3,9163
C08CA09 Lacidipine (O) 5458,544 g 0,004 g 2,8111
C08CA13 Lercanidipine (O) 34588,8 g 0,01 g 7,1251
C08D SELECTIVE CALCIUM CHANNEL BLOCKERS WITH
DIRECT CARDIAC EFFECTS 1,3369
C08DA Phenylalkylamine derivatives 1,2170
C08DA01 Verapamil (O) 141780 g 0,24 g 1,2169
C08DA01 Verapamil (P) 10,525 g 0,24 g 0,0001
C08DB Benzothiazepine derivatives 0,1199
C08DB01 Diltiazem (O) 13971,6 g 0,24 g 0,1199
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM 207,0866
C09A ACE INHIBITORS, PLAIN 72,7975
C09AA ACE inhibitors, plain 72,7975
C09AA01 Captopril (O) 359 g 0,05 g 0,0148
C09AA02 Enalapril (O) 34805,66 g 0,01 g 7,1698
C09AA02 Enalapril (P) 10,1875 g 0,01 g 0,0021
C09AA04 Perindopril (O) 16900,14 g 0,004 g 8,7033
C09AA05 Ramipril (O) 64093,595 g 2,5 mg 52,8117
C09AA09 Fosinopril (O) 29211,56 g 0,015 g 4,0116
C09AA10 Trandolapril (O) 81,704 g 0,002 g 0,0842
C09B ACE INHIBITORS, COMBINATIONS 57,2270
C09BA ACE inhibitors and diuretics 28,6124
C09BA02 Enalapril+Hydrochlorothiazide (O) 2418812 pieces 1 pieces 4,9826
C09BA04 Perindopril+Indapamide (O) 9832740 pieces 1 pieces 20,2549
C09BA05 Ramipril+Hydrochlorothiazide (O) 1121282 pieces 1 pieces 2,3098
C09BA06 Quinapril+Hydrochlorothiazide (O) 150 pieces 1 pieces 0,0003
C09BA09 Fosinopril+Hydrochlorothiazide (O) 516888 pieces 1 pieces 1,0648
C09BB ACE inhibitors and calcium channel blockers 12,7735
C09BB03 Lisinopril+Amlodipine (O) 734790 pieces 1 pieces 1,5136
C09BB04 Perindopril+Amlodipine (O) 4482630 pieces 1 pieces 9,2340
C09BB07 Ramipril+Amlodipine (O) 746490 pieces 1 pieces 1,5377
C09BB10 Trandolapril+Verapamil (O) 236992 pieces 1 pieces 0,4882
C09BX ACE inhibitors, other combinations 15,8411
C09BX01 Perindopril+Amlodipine+Indapamide (O) 7690080 pieces 1 pieces 15,8411
C09C ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS), PLAIN 43,1342
C09CA Angiotensin II receptor blockers (ARBs), plain 43,1342
C09CA01 Losartan (O) 79278,3 g 0,05 g 3,2662
C09CA02 Eprosartan (O) 823,2 g 0,6 g 0,0028
C09CA03 Valsartan (O) 160637,12 g 0,08 g 4,1363
C09CA06 Candesartan (O) 42075,84 g 0,008 g 10,8342
C09CA07 Telmisartan (O) 419850,96 g 0,04 g 21,6217
C09CA08 Olmesartan medoxomil (O) 31776,92 g 0,02 g 3,2729
11/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
C09D ANGIOTENSIN II RECEPTOR BLOCKERS (ARBS),
COMBINATIONS 33,9279
C09DA Angiotensin II receptor blockers (ARBs) and diuretics 14,6674
C09DA01 Losartan+Hydrochlorothiazide (O) 815330 pieces 1 pieces 1,6795
C09DA03 Valsartan+Hydrochlorothiazide (O) 831712 pieces 1 pieces 1,7133
C09DA06 Candesartan+Hydrochlorothiazide (O) 1099280 pieces 1 pieces 2,2645
C09DA07 Telmisartan+Hydrochlorothiazide (O) 4109742 pieces 1 pieces 8,4658
C09DA08 Olmesartan medoxomil+Hydrochlorothiazide (O) 264240 pieces 1 pieces 0,5443
C09DB Angiotensin II receptor blockers (ARBs) and calcium channel
blockers 13,5183
C09DB01 Valsartan+Amlodipine (O) 230026 pieces 1 pieces 0,4738
C09DB02 Olmesartan medoxomil+Amlodipine (O) 3086804 pieces 1 pieces 6,3586
C09DB04 Telmisartan+Amlodipine (O) 3179484 pieces 1 pieces 6,5496
C09DB07 Candesartan+Amlodipine (O) 66164 pieces 1 pieces 0,1363
C09DX Angiotensin II receptor blockers (ARBs), other combinations 5,7422
C09DX01 Valsartan+Amlodipine+Hydrochlorothiazide (O) 3696 pieces 1 pieces 0,0076
C09DX03 Olmesartan medoxomil+Amlodipine+Hydrochlorothiazide (O) 2415476 pieces 1 pieces 4,9757
C09DX04 Valsartan+Sacubitril (O) 368368 pieces 1 pieces 0,7588
C10 LIPID MODIFYING AGENTS 88,3076
C10A LIPID MODIFYING AGENTS, PLAIN 84,9056
C10AA HMG CoA reductase inhibitors 83,6112
C10AA01 Simvastatin (O) 60920,2 g 0,03 g 4,1831
C10AA03 Pravastatin (O) 3834,6 g 0,03 g 0,2633
C10AA04 Fluvastatin (O) 14976,64 g 0,06 g 0,5142
C10AA05 Atorvastatin (O) 330680,4 g 0,02 g 34,0592
C10AA07 Rosuvastatin (O) 216469,24 g 0,01 g 44,5915
C10AB Fibrates 0,6805
C10AB05 Fenofibrate (O) 66072 g 0,2 g 0,6805
C10AC Bile acid sequestrants 0,0015
C10AC01 Colestyramine (O) 9800 g 14 g 0,0014
C10AC02 Colestipol (O) 250 g 20 g <0,0001
C10AX Other lipid modifying agents 0,6125
C10AX09 Ezetimibe (O) 2834,8 g 0,01 g 0,5840
C10AX13 Evolocumab (P) 86,52 g 10 mg 0,0178
C10AX14 Alirocumab (P) 28,05 g 5,4 mg 0,0107
C10AX80 Omega-3-acid ethyl esters 90 (O) 40740 g
C10AX80 Omega-3-acid ethyl esters 90 (O) 168336 pieces
C10B LIPID MODIFYING AGENTS, COMBINATIONS 3,4020
C10BA Combinations of various lipid modifying agents 2,7743
C10BA05 Atorvastatin+Ezetimibe (O) 142860 pieces 1 pieces 0,2943
C10BA06 Rosuvastatin+Ezetimibe (O) 1203900 pieces 1 pieces 2,4800
C10BX Lipid modifying agents in combination with other drugs 0,6277
C10BX11 Atorvastatin+Amlodipine+Perindopril (O) 204180 pieces 1 pieces 0,4206
C10BX13 Rosuvastatin+Perindopril+Indapamide (O) 83820 pieces 1 pieces 0,1727
C10BX15 Atorvastatin+Perindopril (O) 16740 pieces 1 pieces 0,0345
D DERMATOLOGICALS 1,8152
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE 0,9776
D01A ANTIFUNGALS FOR TOPICAL USE
D01AC Imidazole and triazole derivatives
D01AC01 Clotrimazole (C) 502455,4 g
D01AC05 Isoconazole (C) 253810 g
D01AC08 Ketoconazole (C) 80500 ml
D01AC08 Ketoconazole (C) 1123900,2 g
D01AC80 Isoconazole+Diflucortolone (C) 923940 g
D01AC81 Clotrimazole+Hexamidine (C) 120360 g
D01AE Other antifungals for topical use
D01AE14 Ciclopirox (C) 48,312 g
D01AE15 Terbinafine (C) 520571 g
D01AE16 Amorolfine (C) 27837,5 ml
D01AE22 Naftifine (C) 158750 ml
D01AE22 Naftifine (C) 204045 g
D01B ANTIFUNGALS FOR SYSTEMIC USE 0,9776
12/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D01BA Antifungals for systemic use 0,9776
D01BA01 Griseofulvin (O) 612,5 g 0,5 g 0,0025
D01BA02 Terbinafine (O) 118336,5 g 0,25 g 0,9751
D02 EMOLLIENTS AND PROTECTIVES
D02A EMOLLIENTS AND PROTECTIVES
D02AB Zinc products
D02AB80 Zinc oxide (C) 337980 g
D02AE Carbamide products
D02AE01 Urea (C) 42550 g
D02B PROTECTIVES AGAINST UV-RADIATION
D02BA Protectives against UV-radiation for topical use
D02BA01 4-Aminobenzoic acid (O) 720 g
D03 PREPARATIONS FOR TREATMENT OF WOUNDS AND
ULCERS
D03A CICATRIZANTS
D03AX Other cicatrizants
D03AX03 Dexpanthenol (C) 3965440 g
D03AX81 Heparin sodium+Allantoin+Extract of Cepae (C) 121020 g
D03AX83 Dexpanthenol+Chlorhexidine (C) 2171040 g
D03B ENZYMES
D03BA Proteolytic enzymes
D03BA80 Collagenase+Chloramphenicol (C) 90 g
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS,
ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS,
ETC.
D04AA Antihistamines for topical use
D04AA09 Chloropyramine (P) 1 g
D05 ANTIPSORIATICS 0,0510
D05A ANTIPSORIATICS FOR TOPICAL USE
D05AA Tars
D05AA85 Coal tar+Salicylic acid (C) 675400 ml
D05AX Other antipsoriatics for topical use
D05AX80 Calcipotriol+Betamethasone (C) 969120 g
D05B ANTIPSORIATICS FOR SYSTEMIC USE 0,0510
D05BB Retinoids for treatment of psoriasis 0,0510
D05BB02 Acitretin (O) 866,4 g 0,035 g 0,0510
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR
DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE
D06AX Other antibiotics for topical use
D06AX01 Fusidic acid (C) 199785 g
D06AX02 Chloramphenicol (C) 500 g
D06AX09 Mupirocin (C) 1125 g
D06AX80 Bacitracin+Neomycin (C) 50550 g
D06AX84 Chloramphenicol+Methyluracil (C) 4800 g
D06B CHEMOTHERAPEUTICS FOR TOPICAL USE
D06BA Sulfonamides
D06BA01 Silver sulfadiazine (C) 1596065 g
D06BB Antivirals
D06BB03 Aciclovir (C) 198966 g
D06BB04 Podophyllotoxin (C) 1564,5 ml
D06BB10 Imiquimod (C) 5442 g
D06BB81 Aciclovir+Hydrocortisone (C) 27100 g
D06BX Other chemotherapeutics
D06BX01 Metronidazole (C) 85026,975 g
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AA Corticosteroids, weak (group I)
D07AA02 Hydrocortisone (C) 609050 g
13/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D07AB Corticosteroids, moderately potent (group II)
D07AB09 Triamcinolone (C) 260,0045 g
D07AC Corticosteroids, potent (group III)
D07AC01 Betamethasone (C) 140415 g
D07AC04 Fluocinolone acetonide (C) 345 g
D07AC13 Mometasone (C) 341080 ml
D07AC13 Mometasone (C) 1177992,465 g
D07AC14 Methylprednisolone aceponate (C) 617415 g
D07AC17 Fluticasone (C) 46080 g
D07AD Corticosteroids, very potent (group IV)
D07AD01 Clobetasol (C) 82025 ml
D07AD01 Clobetasol (C) 938206,9625 g
D07B CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS
D07BA Corticosteroids, weak, combinations with antiseptics
D07BA80 Hydrocortisone+Chlorhexidine (C) 337140 g
D07BC Corticosteroids, potent, combinations with antiseptics
D07BC80 Betamethasone+Salicylic acid (C) 21030 g
D07BC80 Betamethasone+Salicylic acid (C) 945250 ml
D07C CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
D07CA Corticosteroids, weak, combinations with antibiotics
D07CA83 Hydrocortisone+Fusidic acid (C) 78090 g
D07CC Corticosteroids, potent, combinations with antibiotics
D07CC80 Betamethasone+Fusidic acid (C) 601440 g
D07CC83 Betamethasone+Gentamicin (C) 120 g
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XA Corticosteroids, weak, other combinations
D07XA81 Prednisolone+Salicylic acid (C) 232700 ml
D07XC Corticosteroids, potent, other combinations
D07XC03 Mometasone+Salicylic acid (C) 400 g
D08 ANTISEPTICS AND DISINFECTANTS
D08A ANTISEPTICS AND DISINFECTANTS
D08AG Iodine products
D08AG02 Povidone, iodinated (C) 1134220 ml
D08AG02 Povidone, iodinated (C) 3790020 g
D08AG03 Iodine (C) 893960 ml
D08AJ Quaternary ammonium compounds
D08AJ81 Octenidine+Phenoxyethanol (C) 11159000 ml
D08AX Other antiseptics and disinfectants
D08AX82 Tar+Castor oil+Xeroformium (C) 6150 g
D08AX83 Brilliant Green (C) 241620 ml
D10 ANTI-ACNE PREPARATIONS 0,6570
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AD Retinoids for topical use in acne
D10AD01 Tretinoin (C) 41970 g
D10AD03 Adapalene (C) 51480 g
D10AD80 Adapalene+Benzoyl peroxide (C) 114300 g
D10AD81 Tretinoin+Erythromycin (C) 24030 g
D10AF Antiinfectives for treatment of acne
D10AF01 Clindamycin (C) 2250 ml
D10AF02 Erythromycin (C) 348600 ml
D10AF81 Clindamycin+Benzoyl peroxide (C) 297975 g
D10AF82 Clindamycin+Tretinoin (C) 147360 g
D10AX Other anti-acne preparations for topical use
D10AX03 Azelaic acid (C) 314574 g
D10B ANTI-ACNE PREPARATIONS FOR SYSTEMIC USE 0,6570
D10BA Retinoids for treatment of acne 0,6570
D10BA01 Isotretinoin (O) 9567,6 g 0,03 g 0,6570
D11 OTHER DERMATOLOGICAL PREPARATIONS 0,1296
D11A OTHER DERMATOLOGICAL PREPARATIONS 0,1296
D11AF Wart and anti-corn preparations
D11AF80 Salicylic acid+Lactic acid (C) 78075 ml
14/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
D11AH Agents for dermatitis, excluding corticosteroids 0,0484
D11AH01 Tacrolimus (C) 108540 g
D11AH02 Pimecrolimus (C) 226350 g
D11AH05 Dupilumab (P) 502,4 g 21,4 mg 0,0484
D11AX Other dermatologicals 0,0813
D11AX01 Minoxidil (C) 207300 ml
D11AX10 Finasteride (O) 39,452 g 0,001 g 0,0813
D11AX16 Eflornithine (C) 480 g
D11AX21 Brimonidine (C) 90 g
D11AX22 Ivermectin (C) 67860 g
D11AX82 Hydroquinone+Fluocinolone acetonide+Tretinoin (C) 30 g
G GENITO URINARY SYSTEM AND SEX HORMONES 56,4804
G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS 0,7699
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL.
COMBINATIONS WITH CORTICOSTEROIDS 0,7699
G01AA Antibiotics 0,0420
G01AA01 Nystatin (O) 1200000 U
G01AA10 Clindamycin (V) 2041,1 g 0,1 g 0,0420
G01AC Quinoline derivatives 0,0434
G01AC05 Dequalinium (V) 421,14 g 20 mg 0,0434
G01AF Imidazole derivatives 0,6845
G01AF01 Metronidazole (V) 9998 g 0,5 g 0,0412
G01AF02 Clotrimazole (V) 26696 g 0,1 g 0,5499
G01AF05 Econazole (V) 4533,3 g 0,1 g 0,0934
G02 OTHER GYNECOLOGICALS 4,0514
G02A UTEROTONICS 0,1418
G02AB Ergot alkaloids 0,0022
G02AB01 Methylergometrine (P) 0,2168 g 0,2 mg 0,0022
G02AD Prostaglandins 0,1395
G02AD02 Dinoprostone (P) 0,42 g
G02AD02 Dinoprostone (V) 1,8739 g 0,5 mg 0,0077
G02AD06 Misoprostol (O) 12,799 g 0,2 mg 0,1318
G02B CONTRACEPTIVES FOR TOPICAL USE 2,3182
G02BA Intrauterine contraceptives 0,0177
G02BA03 Levonorgestrel (V) 8595 pieces 1 pieces 0,0177
G02BB Intravaginal contraceptives 2,3005
G02BB01 Etonogestrel+Ethinylestradiol (V) 39021 pieces 0,036 pieces 2,2328
G02BB81 Benzalkonium chloride (V) 32880 pieces 1 pieces 0,0677
G02BB81 Benzalkonium chloride (V) 37656 g
G02C OTHER GYNECOLOGICALS 1,5914
G02CA Sympathomimetics, labour repressants
G02CA80 Hexoprenaline (P) 0,0103 g
G02CB Prolactine inhibitors 0,1391
G02CB01 Bromocriptine (O) 271,425 g 0,005 g 0,1118
G02CB03 Cabergoline (O) 6,62 g 0,5 mg 0,0273
G02CX Other gynecologicals 1,4523
G02CX01 Atosiban (P) 1,0388 g 0,165 g <0,0001
G02CX03 Agni casti fructus (O) 386280 pieces 1 pieces 0,7957
G02CX04 Cimicifugae rhizoma (O) 637440 pieces 2 pieces 0,6565
G03 SEX HORMONES AND MODULATORS OF THE GENITAL
SYSTEM 30,3378
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE 23,3445
G03AA Progestogens and estrogens, fixed combinations 18,3957
G03AA07 Levonorgestrel+Ethinylestradiol (O) 220724 pieces 1 pieces 0,4547
G03AA09 Desogestrel+Ethinylestradiol (O) 360612 pieces 0,75 pieces 0,9905
G03AA10 Gestodene+Ethinylestradiol (O) 2008944 pieces 0,75 pieces 5,5178
G03AA12 Drospirenone+Ethinylestradiol (O) 1102500 pieces 1 pieces 2,2711
G03AA12 Drospirenone+Ethinylestradiol (O) 1553874 pieces 0,75 pieces 4,2679
G03AA13 Norelgestromin+Ethinylestradiol (TD) 89901 pieces 0,107 pieces 1,7308
G03AA14 Nomegestrol+Estradiol (O) 1512 pieces 1 pieces 0,0031
G03AA15 Chlormadinone+Ethinylestradiol (O) 137592 pieces 0,75 pieces 0,3779
G03AA16 Dienogest+Ethinylestradiol (O) 1012907 pieces 0,75 pieces 2,7820
15/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G03AB Progestogens and estrogens, sequential preparations 0,1666
G03AB05 Desogestrel+Ethinylestradiol (O) 1650 pieces 0,75 pieces 0,0045
G03AB08 Dienogest+Estradiol valerate (O) 78680 pieces 1 pieces 0,1621
G03AC Progestogens 4,7022
G03AC08 Etonogestrel (P) 63,512 g 68 mcg 1,9240
G03AC09 Desogestrel (O) 1326724 pieces 1 pieces 2,7330
G03AC10 Drospirenone (O) 21952 pieces 1 pieces 0,0452
G03AD Emergency contraceptives 0,0800
G03AD01 Levonorgestrel (O) 56,8935 g 1,5 mg 0,0781
G03AD02 Ulipristal (O) 27,27 g 0,03 g 0,0019
G03B ANDROGENS 0,2711
G03BA 3-oxoandrosten (4) derivatives 0,2711
G03BA03 Testosterone (O) 14,4 g 0,12 g 0,0002
G03BA03 Testosterone (P) 2357,75 g 0,018 g 0,2698
G03BA03 Testosterone (TD) 25,76 g 0,05 g 0,0011
G03C ESTROGENS 1,5141
G03CA Natural and semisynthetic estrogens, plain 1,5000
G03CA03 Estradiol (C, V) 60875 g
G03CA03 Estradiol (O) 834,232 g 2 mg 0,8592
G03CA03 Estradiol (TD) 53,1216 g 1,53 mg 0,0715
G03CA03 Estradiol (TD) 77,7 g 1 mg 0,1601
G03CA03 Estradiol (V) 2,8688 g 0,025 mg 0,2364
G03CA04 Estriol (V) 16,7775 g 0,2 mg 0,1728
G03CA80 Estradiol+Prednisolone (C) 61150 g
G03CX Other estrogens 0,0141
G03CX01 Tibolone (O) 17,15 g 2,5 mg 0,0141
G03D PROGESTOGENS 2,2967
G03DA Pregnen (4) derivatives 1,5341
G03DA02 Medroxyprogesterone (O) 74,55 g 0,005 g 0,0307
G03DA02 Medroxyprogesterone (P) 291,465 g 0,007 g 0,0858
G03DA04 Progesterone (O) 9426 g 0,3 g 0,0647
G03DA04 Progesterone (P) 314,9915 g 0,005 g 0,1298
G03DA04 Progesterone (V) 53438,1 g 0,09 g 1,2231
G03DB Pregnadien derivatives 0,7619
G03DB01 Dydrogesterone (O) 2673,4 g 0,01 g 0,5507
G03DB08 Dienogest (O) 205,016 g 2 mg 0,2112
G03DC Estren derivatives 0,0007
G03DC02 Norethisterone (O) 1,8 g 0,005 g 0,0007
G03F PROGESTOGENS AND ESTROGENS IN COMBINATION 2,0851
G03FA Progestogens and estrogens, fixed combinations 1,6641
G03FA01 Norethisterone+Estradiol (O) 493276 pieces 1 pieces 1,0161
G03FA14 Dydrogesterone+Estradiol (O) 139468 pieces 1 pieces 0,2873
G03FA17 Drospirenone+Estradiol (O) 175112 pieces 1 pieces 0,3607
G03FB Progestogens and estrogens, sequential preparations 0,4210
G03FB05 Norethisterone+Estradiol (O) 147168 pieces 1 pieces 0,3032
G03FB08 Dydrogesterone+Estradiol (O) 57204 pieces 1 pieces 0,1178
G03G GONADOTROPINS AND OTHER OVULATION STIMULANTS 0,4704
G03GA Gonadotropins 0,1804
G03GA05 Follitropin alfa (P) 5525175 U 75 U 0,1518
G03GA07 Lutropin alfa (P) 679650 U 75 U 0,0187
G03GA08 Choriogonadotropin alfa (P) 0,859 g 0,25 mg 0,0071
G03GA30 Follitropin alfa+Lutropin alfa (P) 1427 doses 1 doses 0,0029
G03GB Ovulation stimulants, synthetic 0,2899
G03GB02 Clomifene (O) 1266,7 g 0,009 g 0,2899
G03H ANTIANDROGENS 0,3519
G03HA Antiandrogens, plain 0,0739
G03HA01 Cyproterone (O) 3587,5 g 0,1 g 0,0739
G03HB Antiandrogens and estrogens 0,2780
G03HB01 Cyproterone+Estrogen (O) 101220 pieces 0,75 pieces 0,2780
G03X OTHER SEX HORMONES AND MODULATORS OF THE
GENITAL SYSTEM 0,0040
16/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
G03XB Progesterone receptor modulators 0,0038
G03XB01 Mifepristone (O) 840 g 0,6 g 0,0029
G03XB02 Ulipristal (O) 2,24 g 5 mg 0,0009
G03XC Selective estrogen receptor modulators 0,0002
G03XC01 Raloxifene (O) 5,04 g 0,06 g 0,0002
G04 UROLOGICALS 21,3212
G04B UROLOGICALS 3,8300
G04BD Drugs for urinary frequency and incontinence 2,2222
G04BD04 Oxybutynin (O) 4560,6 g 0,015 g 0,6263
G04BD06 Propiverine (O) 14,7 g 0,03 g 0,0010
G04BD07 Tolterodine (O) 640,416 g 0,004 g 0,3298
G04BD08 Solifenacin (O) 945,45 g 0,005 g 0,3895
G04BD09 Trospium chloride (O) 3707,55 g 0,04 g 0,1909
G04BD12 Mirabegron (O) 16617 g 50 mg 0,6846
G04BE Drugs used in erectile dysfunction 1,5962
G04BE01 Alprostadil (P) 0,0461 g 0,02 mg 0,0047
G04BE03 Sildenafil (O) 26924,2 g 0,05 g 1,1092
G04BE08 Tadalafil (O) 2035,76 g 0,01 g 0,4194
G04BE09 Vardenafil (O) 55,12 g 0,01 g 0,0114
G04BE10 Avanafil (O) 2498,8 g 0,1 g 0,0515
G04BX Other urologicals 0,0116
G04BX14 Dapoxetin (O) 169,29 g 0,03 g 0,0116
G04BX80 Centaury+Lovage root+Rosemary leaf (O) 1137060 pieces
G04BX90 Extr. prostatae (P) 1000 pieces
G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY 17,4913
G04CA Alpha-adrenoreceptor antagonists 14,4261
G04CA01 Alfuzosin (O) 8334,6 g 7,5 mg 2,2892
G04CA02 Tamsulosin (O) 1603,536 g 0,4 mg 8,2580
G04CA04 Silodosin (O) 789,36 g 8 mg 0,2033
G04CA52 Tamsulosin+Dutasteride (O) 1784340 pieces 1 pieces 3,6756
G04CB Testosterone-5-alpha reductase inhibitors 0,5665
G04CB01 Finasteride (O) 451,67 g 0,005 g 0,1861
G04CB02 Dutasteride (O) 92,325 g 0,5 mg 0,3804
G04CX Other drugs used in benign prostatic hypertrophy 2,4988
G04CX02 Sabalis serrulatae fructus (O) 388166,4 g 0,32 g 2,4988
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX
HORMONES AND INSULINS 31,2564
H01 PITUITARY AND HYPOTHALAMIC HORMONES AND
ANALOGUES 0,4655
H01A ANTERIOR PITUITARY LOBE HORMONES AND
ANALOGUES 0,1784
H01AA ACTH 0,0002
H01AA02 Tetracosactide (P) 0,02 g 0,25 mg 0,0002
H01AB Thyrotropin 0,0003
H01AB01 Thyrotropin alfa (P) 0,1368 g 0,9 mg 0,0003
H01AC Somatropin and somatropin agonists 0,1604
H01AC01 Somatropin (P) 155737,6372 U 2 U 0,1604
H01AX Other anterior pituitary lobe hormones and analogues 0,0175
H01AX01 Pegvisomant (P) 84,9 g 0,01 g 0,0175
H01B POSTERIOR PITUITARY LOBE HORMONES 0,1513
H01BA Vasopressin and analogues 0,1037
H01BA01 Argipressin (P) 44400 U 40 U 0,0023
H01BA02 Desmopressin (N) 0,015 g 0,025 mg 0,0012
H01BA02 Desmopressin (P) 0,0201 g 0,004 mg 0,0104
H01BA02 Desmopressin (SL) 10,4688 g 0,24 mg 0,0899
H01BB Oxytocin and analogues 0,0476
H01BB01 Demoxytocin (O) 850000 U 100 U 0,0175
H01BB02 Oxytocin (P) 195900 U 15 U 0,0269
H01BB03 Carbetocin (P) 0,1556 g 0,1 mg 0,0032
H01C HYPOTHALAMIC HORMONES 0,1358
H01CA Gonadotropin-releasing hormones
H01CA01 Gonadorelin (P) 0,0037 g
17/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
H01CB Somatostatin and analogues 0,1137
H01CB02 Octreotide (P) 9,043 g 0,7 mg 0,0266
H01CB03 Lanreotide (P) 112,05 g 3 mg 0,0769
H01CB05 Pasireotide (P) 5,94 g 1,2 mg 0,0102
H01CC Anti-gonadotropin-releasing hormones 0,0220
H01CC02 Cetrorelix (P) 2,6718 g 0,25 mg 0,0220
H02 CORTICOSTEROIDS FOR SYSTEMIC USE 9,8660
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN 9,8617
H02AA Mineralocorticoids 0,1765
H02AA02 Fludrocortisone (O) 8,57 g 0,1 mg 0,1765
H02AB Glucocorticoids 9,6852
H02AB01 Betamethasone (P) 15,1965 g 1,5 mg 0,0209
H02AB02 Dexamethasone (O) 1398,13 g 1,5 mg 1,9200
H02AB02 Dexamethasone (P) 950,2 g 1,5 mg 1,3049
H02AB04 Methylprednisolone (O) 7474 g 7,5 mg 2,0528
H02AB04 Methylprednisolone (P) 4749,35 g 0,02 g 0,4892
H02AB06 Prednisolone (O) 13905 g 0,01 g 2,8644
H02AB06 Prednisolone (P) 1270,85 g 0,01 g 0,2618
H02AB08 Triamcinolone (O) 11,2 g 7,5 mg 0,0031
H02AB08 Triamcinolone (P) 1562,4 g 7,5 mg 0,4291
H02AB09 Hydrocortisone (O) 4251,65 g 0,03 g 0,2919
H02AB09 Hydrocortisone (P) 680,4 g 0,03 g 0,0467
H02AB13 Deflazacort (O) 3 g 15 mg 0,0004
H02B CORTICOSTEROIDS FOR SYSTEMIC USE,
COMBINATIONS 0,0043
H02BX Corticosteroids for systemic use, combinations 0,0043
H02BX80 Hydrocortisone+Lidocaine (P) 56,625 g 0,03 g 0,0039
H02BX81 Methylprednisolone+Bupivacaine (P) 4 g 20 mg 0,0004
H03 THYROID THERAPY 20,8799
H03A THYROID PREPARATIONS 19,6724
H03AA Thyroid hormones 19,6724
H03AA01 Levothyroxine sodium (O) 1432,35 g 0,15 mg 19,6704
H03AA02 Liothyronine (O) 0,058 g 0,06 mg 0,0020
H03AA03 Levothyroxine sodium+Liothyronine (O) 300 pieces
H03AA04 Tiratricol (O) 0,189 g
H03B ANTITHYROID PREPARATIONS 1,2075
H03BA Thiouracils 0,1443
H03BA02 Propylthiouracil (O) 7004,5 g 0,1 g 0,1443
H03BB Sulfur-containing imidazole derivatives 1,0632
H03BB02 Thiamazole (O) 5161,5 g 0,01 g 1,0632
H03BC Perchlorates
H03BC01 Sodium perchlorate (O) 72 g
H04 PANCREATIC HORMONES 0,0010
H04A GLYCOGENOLYTIC HORMONES 0,0010
H04AA Glycogenolytic hormones 0,0010
H04AA01 Glucagon (P) 0,47 g 0,001 g 0,0010
H05 CALCIUM HOMEOSTASIS 0,0440
H05B ANTI-PARATHYROID AGENTS 0,0440
H05BX Other anti-parathyroid agents 0,0440
H05BX01 Cinacalcet (O) 1276,8 g 0,06 g 0,0438
H05BX02 Paricalcitol (O) 0,0001 g 2 mcg 0,0001
J ANTIINFECTIVES FOR SYSTEMIC USE 17,7055
J01 ANTIBACTERIALS FOR SYSTEMIC USE 10,0665
J01A TETRACYCLINES 1,3317
J01AA Tetracyclines 1,3317
J01AA02 Doxycycline (O) 64635 g 0,1 g 1,3314
J01AA02 Doxycycline (P) 3,5 g 0,1 g 0,0001
J01AA07 Tetracycline (O) 5 g 1 g <0,0001
J01AA12 Tigecycline (P) 8 g 0,1 g 0,0002
J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS 3,7400
J01CA Penicillins with extended spectrum 1,2931
J01CA01 Ampicillin (P) 18100 g 6 g 0,0062
18/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J01CA04 Amoxicillin (O) 937090,5 g 1,5 g 1,2869
J01CE Beta-lactamase sensitive penicillins 0,0914
J01CE01 Benzylpenicillin (P) 29160 g 3,6 g 0,0167
J01CE02 Phenoxymethylpenicillin (O) 71629,8 g 2 g 0,0738
J01CE08 Benzathine benzylpenicillin (P) 1638 g 3,6 g 0,0009
J01CE80 Benzathine benzylpenicillin+Procaine benzylpenicillin (P) 17,1 g 3,6 g <0,0001
J01CF Beta-lactamase resistant penicillins 0,0814
J01CF04 Oxacillin (P) 78940 g 2 g 0,0813
J01CF05 Flucloxacillin (O) 120 g 2 g 0,0001
J01CR Combinations of penicillins, incl. beta-lactamase inhibitors 2,2741
J01CR01 Ampicillin+Sulbactam (P) 53366 g 6 g 0,0183
J01CR02 Amoxicillin+Clavulanic acid (O) 1415868,3 g 1,5 g 1,9444
J01CR02 Amoxicillin+Clavulanic acid (P) 300895 g 3 g 0,2066
J01CR04 Sultamicillin (O) 40374 g 1,5 g 0,0554
J01CR05 Piperacillin+Tazobactam (P) 334928 g 14 g 0,0493
J01D OTHER BETA-LACTAM ANTIBACTERIALS 1,3922
J01DB First-generation cephalosporins 0,1960
J01DB01 Cefalexin (O) 30 g 2 g <0,0001
J01DB04 Cefazolin (P) 94420 g 3 g 0,0648
J01DB05 Cefadroxil (O) 127335 g 2 g 0,1312
J01DC Second-generation cephalosporins 1,0486
J01DC01 Cefoxitin (P) 12305 g 6 g 0,0042
J01DC02 Cefuroxime (O) 206940,25 g 0,5 g 0,8526
J01DC02 Cefuroxime (P) 227040 g 3 g 0,1559
J01DC10 Cefprozil (O) 17427,5 g 1 g 0,0359
J01DD Third-generation cephalosporins 0,0559
J01DD01 Cefotaxime (P) 51070 g 4 g 0,0263
J01DD02 Ceftazidime (P) 11703 g 4 g 0,0060
J01DD04 Ceftriaxone (P) 19970 g 2 g 0,0206
J01DD81 Ceftazidime+Avibactam (P) 8700 g 6 g 0,0030
J01DE Fourth-generation cephalosporins 0,0109
J01DE01 Cefepime (P) 21210 g 4 g 0,0109
J01DH Carbapenems 0,0808
J01DH02 Meropenem (P) 68314 g 3 g 0,0469
J01DH03 Ertapenem (P) 10650 g 1 g 0,0219
J01DH51 Imipenem+Cilastatin (P) 11600 g 2 g 0,0119
J01E SULFONAMIDES AND TRIMETHOPRIM 0,3656
J01EA Trimethoprim and derivatives 0,0295
J01EA01 Trimethoprim (O) 5730 g 0,4 g 0,0295
J01EE Combinations of sulfonamides and trimethoprim, incl.
derivatives 0,3361
J01EE01 Sulfamethoxazole+Trimethoprim (O) 2544 pieces 4 pieces 0,0013
J01EE01 Sulfamethoxazole+Trimethoprim (O) 286130 pieces 2 pieces 0,2947
J01EE01 Sulfamethoxazole+Trimethoprim (O) 623500 ml 40 ml 0,0321
J01EE01 Sulfamethoxazole+Trimethoprim (P) 77445 ml 20 ml 0,0080
J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS 1,8609
J01FA Macrolides 1,6962
J01FA01 Erythromycin (O) 135 g 1 g 0,0003
J01FA01 Erythromycin (P) 80 g 1 g 0,0002
J01FA09 Clarithromycin (O) 281758,5 g 0,5 g 1,1608
J01FA09 Clarithromycin (P) 2873,5 g 1 g 0,0059
J01FA10 Azithromycin (O) 77038,5 g 0,3 g 0,5290
J01FF Lincosamides 0,1648
J01FF01 Clindamycin (O) 89815,2 g 1,2 g 0,1542
J01FF01 Clindamycin (P) 9249 g 1,8 g 0,0106
J01G AMINOGLYCOSIDE ANTIBACTERIALS 0,0218
J01GB Other aminoglycosides 0,0218
J01GB01 Tobramycin (I) 150,528 g 0,112 g 0,0028
J01GB01 Tobramycin (I) 604,8 g 0,3 g 0,0042
J01GB01 Tobramycin (P) 80 g 0,24 g 0,0007
J01GB03 Gentamicin (P) 1217,2 g 0,24 g 0,0104
J01GB06 Amikacin (P) 1825 g 1 g 0,0038
19/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J01M QUINOLONE ANTIBACTERIALS 0,7032
J01MA Fluoroquinolones 0,7032
J01MA01 Ofloxacin (O) 3210 g 0,4 g 0,0165
J01MA02 Ciprofloxacin (O) 249480 g 1 g 0,5139
J01MA02 Ciprofloxacin (P) 10306 g 0,8 g 0,0265
J01MA06 Norfloxacin (O) 36384 g 0,8 g 0,0937
J01MA12 Levofloxacin (O) 6210,75 g 0,5 g 0,0256
J01MA12 Levofloxacin (P) 569,5 g 0,5 g 0,0023
J01MA14 Moxifloxacin (O) 4492 g 0,4 g 0,0231
J01MA14 Moxifloxacin (P) 288 g 0,4 g 0,0015
J01X OTHER ANTIBACTERIALS 0,6510
J01XA Glycopeptide antibacterials 0,0281
J01XA01 Vancomycin (P) 27165 g 2 g 0,0280
J01XA02 Teicoplanin (P) 28 g 0,4 g 0,0001
J01XB Polymyxins 0,0023
J01XB01 Colistin (I) 1800000000 U 9000000 U 0,0004
J01XB01 Colistin (I, P) 1590000000 U 9000000 U 0,0004
J01XB01 Colistin (P) 6560000000 U 9000000 U 0,0015
J01XD Imidazole derivatives 0,0284
J01XD01 Metronidazole (P) 20710 g 1,5 g 0,0284
J01XE Nitrofuran derivatives 0,5708
J01XE01 Nitrofurantoin (O) 55422 g 0,2 g 0,5708
J01XX Other antibacterials 0,0213
J01XX01 Fosfomycin (O) 7854 g 3 g 0,0054
J01XX08 Linezolid (O) 5796 g 1,2 g 0,0099
J01XX08 Linezolid (P) 2760 g 1,2 g 0,0047
J01XX09 Daptomycin (P) 169,65 g 0,28 g 0,0012
J02 ANTIMYCOTICS FOR SYSTEMIC USE 0,4090
J02A ANTIMYCOTICS FOR SYSTEMIC USE 0,4090
J02AA Antibiotics 0,0150
J02AA01 Amphotericin (O) 205 g
J02AA01 Amphotericin (P) 255,05 g 0,035 g 0,0150
J02AB Imidazole derivatives 0,0012
J02AB02 Ketoconazole (O) 120 g 0,2 g 0,0012
J02AC Triazole and tetrazole derivatives 0,3822
J02AC01 Fluconazole (O) 15340,3 g 0,2 g 0,1580
J02AC01 Fluconazole (P) 3956 g 0,2 g 0,0407
J02AC02 Itraconazole (O) 13460,2 g 0,2 g 0,1386
J02AC03 Voriconazole (O) 2920,4 g 0,4 g 0,0150
J02AC03 Voriconazole (P) 616,6 g 0,4 g 0,0032
J02AC04 Posaconazole (O) 2764,2 g 0,3 g 0,0190
J02AC04 Posaconazole (P) 688,8 g 0,3 g 0,0047
J02AC05 Isavuconazole (O) 168 g 0,2 g 0,0017
J02AC05 Isavuconazole (P) 110,8 g 0,2 g 0,0011
J02AX Other antimycotics for systemic use 0,0105
J02AX04 Caspofungin (P) 63,61 g 0,05 g 0,0026
J02AX06 Anidulafungin (P) 383,8 g 0,1 g 0,0079
J04 ANTIMYCOBACTERIALS 0,0664
J04A DRUGS FOR TREATMENT OF TUBERCULOSIS 0,0516
J04AB Antibiotics 0,0154
J04AB02 Rifampicin (O) 4429,2 g 0,6 g 0,0152
J04AB02 Rifampicin (P) 63 g 0,6 g 0,0002
J04AC Hydrazides 0,0154
J04AC01 Isoniazid (O) 2250 g 0,3 g 0,0154
J04AD Thiocarbamide derivatives 0,0055
J04AD01 Protionamide (O) 2000 g 0,75 g 0,0055
J04AK Other drugs for treatment of tuberculosis 0,0115
J04AK05 Bedaquiline (O) 376 g 86 mg 0,0090
J04AK06 Delamanid (O) 240 g 0,2 g 0,0025
J04AK08 Pretomanid (O) 291,2 g
J04AM Combinations of drugs for treatment of tuberculosis 0,0037
J04AM02 Rifampicin+Isoniazid (O) 7200 pieces 4 pieces 0,0037
20/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J04B DRUGS FOR TREATMENT OF LEPRA 0,0148
J04BA Drugs for treatment of lepra 0,0148
J04BA02 Dapsone (O) 360 g 0,05 g 0,0148
J05 ANTIVIRALS FOR SYSTEMIC USE 7,1637
J05A DIRECT ACTING ANTIVIRALS 7,1637
J05AB Nucleosides and nucleotides excl. reverse transcriptase
inhibitors 0,4540
J05AB01 Aciclovir (O) 388037 g 4 g 0,1998
J05AB01 Aciclovir (P) 2876,25 g 4 g 0,0015
J05AB06 Ganciclovir (P) 419,5 g 0,5 g 0,0017
J05AB09 Famciclovir (O) 189 g 0,75 g 0,0005
J05AB11 Valaciclovir (O) 280250 g 3 g 0,1924
J05AB12 Cidofovir (P) 1,125 g 0,025 g 0,0001
J05AB14 Valganciclovir (O) 6355 g 0,9 g 0,0145
J05AB16 Remdesivir (P) 2105 g 0,1 g 0,0434
J05AD Phosphonic acid derivatives 0,0001
J05AD01 Foscarnet sodium (P) 360 g 6,5 g 0,0001
J05AE Protease inhibitors 1,0143
J05AE03 Ritonavir (O) 94131 g 1,2 g 0,1616
J05AE10 Darunavir (O) 496728 g 1,2 g 0,8527
J05AF Nucleoside and nucleotide reverse transcriptase inhibitors 0,1327
J05AF01 Zidovudine (O) 292 g 0,6 g 0,0010
J05AF01 Zidovudine (P) 93 g 0,6 g 0,0003
J05AF05 Lamivudine (O) 575,4 g 0,3 g 0,0040
J05AF06 Abacavir (O) 2582,4 g 0,6 g 0,0089
J05AF07 Tenofovir disoproxil (O) 499,8 g 0,245 g 0,0042
J05AF10 Entecavir (O) 26,19 g 0,5 mg 0,1079
J05AF13 Tenofovir alafenamide (O) 78 g 25 mg 0,0064
J05AG Non-nucleoside reverse transcriptase inhibitors 0,8506
J05AG05 Rilpivirine (O) 10323 g 25 mg 0,8506
J05AH Neuraminidase inhibitors 0,0134
J05AH02 Oseltamivir (O) 974,25 g 0,15 g 0,0134
J05AJ Integrase inhibitors 1,2941
J05AJ01 Raltegravir (O) 473544 g 0,8 g 1,2193
J05AJ03 Dolutegravir (O) 1813,5 g 50 mg 0,0747
J05AP Antivirals for treatment of HCV infections 0,1925
J05AP54 Elbasvir+Grazoprevir (O) 43092 pieces 1 pieces 0,0888
J05AP55 Sofosbuvir+Velpatasvir (O) 2856 pieces 1 pieces 0,0059
J05AP57 Glecaprevir+Pibrentasvir (O) 142464 pieces 3 pieces 0,0978
J05AR Antivirals for treatment of HIV infections, combinations 3,2121
J05AR02 Lamivudine+Abacavir (O) 335190 pieces 1 pieces 0,6905
J05AR03 Tenofovir disoproxil+Emtricitabine (O) 825960 pieces 1 pieces 1,7014
J05AR06 Emtricitabine+Tenofovir disoproxil+Efavirenz (O) 134910 pieces 1 pieces 0,2779
J05AR13 Lamivudine+Abacavir+Dolutegravir (O) 262650 pieces 1 pieces 0,5410
J05AR18 Emtricitabine+Tenofovir alafenamide+Elvitegravir+Cobicistat
(O) 600 pieces 1 pieces 0,0012
J06 IMMUNE SERA AND IMMUNOGLOBULINS
J06A IMMUNE SERA
J06AA Immune sera
J06AA04 Botulinum antitoxin (P) 35 pieces
J06B IMMUNOGLOBULINS
J06BA Immunoglobulins, normal human
J06BA01 Immunoglobulins, normal human, for extravascular a (P) 11217,9 g
J06BA02 Immunoglobulins, normal human, for intravascular a (P) 106802,5 g
J06BB Specific immunoglobulins
J06BB01 Human Anti-D Immunoglobulin (P) 1866375 U
J06BB02 Tetanus immunoglobulin (P) 43000 U
J06BB03 Varicella zoster immunoglobulin (P) 6250 U
J06BB04 Hepatitis B immunoglobulin (P) 6800 U
J06BB05 Rabies immunoglobulin (P) 3000 U
J06BB09 Cytomegalovirus immunoglobulin (P) 70000 U
J06BB82 Regdanvimab (P) 192 g
21/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J06BD Antiviral monoclonal antibodies
J06BD01 Palivizumab (P) 42,45 g
J07 VACCINES
J07A BACTERIAL VACCINES
J07AE Cholera vaccines
J07AE01 Cholera, inactivated, whole cell (O) 84 doses
J07AG Hemophilus influenzae B vaccines
J07AG01 Haemophilus influenzae B, purified antigen conjugated (P) 229 doses
J07AH Meningococcal vaccines
J07AH08 Meningococcus, tetravalent purified polysaccharides antigen
conjugated (P) 453 doses
J07AH09 Meningococcus B, multicomponent vaccine (P) 46 doses
J07AL Pneumococcal vaccines
J07AL01 Pneumococcus, purified polysaccharides antigen (P) 553 doses
J07AL02 Pneumococcus, purified polysaccharides antigen conjugated
(P) 2391 doses
J07AL52 Pneumococcus, purified polysaccharides
antigen+Haemophilus influenzae, conjugated (P) 209 doses
J07AM Tetanus vaccines
J07AM51 Tetanus toxoid+Diphtheria toxoid (P) 48673 doses
J07AN Tuberculosis vaccines
J07AN01 Tuberculosis, live attenuated (P) 2622 pieces
J07AP Typhoid vaccines
J07AP03 Typhoid, purified polysaccharide antigen (P) 737 doses
J07AX Other bacterial vaccines
J07AX80 Diphtheria-tetanus-pertussis (P) 10784 doses
J07B VIRAL VACCINES
J07BA Encephalitis vaccines
J07BA01 Encephalitis, tick borne, inactivated, whole virus (P) 72311 doses
J07BB Influenza vaccines
J07BB02 Influenza, inactivated, split virus or surface antigen (P) 201317 doses
J07BB03 Influenza, live attenuated (N) 2830 doses
J07BC Hepatitis vaccines
J07BC01 Hepatitis B, purified antigen (P) 2316 doses
J07BC02 Hepatitis A, inactivated, whole virus (P) 1490 doses
J07BC80 Hepatitis A, inactivated, whole virus+Hepatitis B, purified
antigen (P) 1037 doses
J07BD Measles vaccines
J07BD52 Measles, live attunated+Rubella, live attenuated+Mumps,
live,attenuated (P) 23986 doses
J07BF Poliomyelitis vaccines
J07BF03 Poliomyelitis, trivalent, inactivated, whole virus (P) 533 doses
J07BG Rabies vaccines
J07BG01 Rabies, inactivated, whole virus (P) 1377 doses
J07BH Rota virus diarrhea vaccines
J07BH02 Rota virus, pentavalent, live, reassorted (O) 79845 doses
J07BK Varicella zoster vaccines
J07BK01 Varicella, live attenuated (P) 1838 doses
J07BK02 Zoster, live attenuated (P) 44 doses
J07BK03 Zoster, purified antigen (P) 4 doses
J07BL Yellow fever vaccines
J07BL01 Yellow fever, live attenuated (P) 711 doses
J07BM Papillomavirus vaccines
J07BM02 Papillomavirus (human types 16, 18) (P) 1 doses
J07BM03 Papillomavirus (human types 6, 11, 16, 18, 31, 33, 45, 52, 58)
(P) 15319 doses
J07BX Other viral vaccines
J07BX03 Covid-19 vaccine (P) 2115397,2 doses
J07C BACTERIAL AND VIRAL VACCINES, COMBINED
J07CA Bacterial and viral vaccines, combined
J07CA02 Diphtheria toxoid+Pertussis, purified antigen+Tetanus
toxoid+Poliomyelitis, trivalent, inactivated, whole virus (P) 16332 doses
22/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
J07CA06
Diphtheria toxoid+Tetanus toxoid+Pertussis, purified
antigen+Poliomyelitis, trivalent, inactivated, whole
virus+Haemophilus influenzae B, purified antigen conjugated
(P)
455 doses
J07CA09
Diphtheria toxoid+Poliomyelitis, trivalent, inactivated, whole
virus+Pertussis, purified antigen+Haemophilus influenzae B,
purified antigen conjugated+Hepatitis B, purified
antigen+Tetanus toxoid (P)
47370 doses
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS 13,0308
L01 ANTINEOPLASTIC AGENTS 0,4860
L01A ALKYLATING AGENTS
L01AA Nitrogen mustard analogues
L01AA01 Cyclophosphamide (O) 660 g
L01AA01 Cyclophosphamide (P) 3690 g
L01AA02 Chlorambucil (O) 18,85 g
L01AA03 Melphalan (O) 4,5 g
L01AA03 Melphalan (P) 21,75 g
L01AA06 Ifosfamide (P) 1995 g
L01AA09 Bendamustine (P) 150,4 g
L01AB Alkyl sulfonates
L01AB01 Busulfan (O) 4 g
L01AB01 Busulfan (P) 1,92 g
L01AB02 Treosulfan (P) 1530 g
L01AC Ethylene imines
L01AC01 Thiotepa (P) 1,965 g
L01AD Nitrosoureas
L01AD01 Carmustine (P) 6,3 g
L01AD02 Lomustine (O) 22,4 g
L01AD04 Streptozocin (P) 16 g
L01AX Other alkylating agents
L01AX03 Temozolomide (O) 668,8 g
L01AX04 Dacarbazine (P) 415 g
L01B ANTIMETABOLITES
L01BA Folic acid analogues
L01BA01 Methotrexate (P) 1165,2 g
L01BA04 Pemetrexed (P) 365 g
L01BB Purine analogues
L01BB02 Mercaptopurine (O) 448,75 g
L01BB03 Tioguanine (O) 6 g
L01BB04 Cladribine (P) 0,42 g
L01BB05 Fludarabine (P) 19,5 g
L01BB06 Clofarabine (P) 1,1 g
L01BC Pyrimidine analogues
L01BC01 Cytarabine (P) 2136 g
L01BC02 Fluorouracil (C) 80 g
L01BC02 Fluorouracil (P) 13025 g
L01BC05 Gemcitabine (P) 5081,4348 g
L01BC06 Capecitabine (O) 256872 g
L01BC07 Azacitidine (P) 315 g
L01BC82 Fluorouracil+Salicylic acid (C) 150 ml
L01BC83 Trifluridine+Tipiracil (O) 16380 pieces
L01C PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS
L01CA Vinca alkaloids and analogues
L01CA01 Vinblastine (P) 2,91 g
L01CA02 Vincristine (P) 2,233 g
L01CA03 Vindesine (P) 0,005 g
L01CA04 Vinorelbine (O) 6,38 g
L01CA04 Vinorelbine (P) 19,55 g
L01CB Podophyllotoxin derivatives
L01CB01 Etoposide (O) 275 g
L01CB01 Etoposide (P) 461,2 g
23/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01CD Taxanes
L01CD01 Paclitaxel (P) 813,2 g
L01CD02 Docetaxel (P) 469,12 g
L01CD04 Cabazitaxel (P) 1,32 g
L01CE Topoisomerase 1 (TOP1) inhibitors
L01CE01 Topotecan (P) 2,12 g
L01CE02 Irinotecan (P) 630 g
L01CX Other plant alkaloids and natural products
L01CX01 Trabectedin (P) 0,009 g
L01D CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
L01DA Actinomycines
L01DA01 Dactinomycin (P) 0,052 g
L01DB Anthracyclines and related substances
L01DB01 Doxorubicin (P) 148,84 g
L01DB02 Daunorubicin (P) 8,12 g
L01DB03 Epirubicin (P) 188,8 g
L01DB06 Idarubicin (P) 1,4 g
L01DB07 Mitoxantrone (P) 0,82 g
L01DC Other cytotoxic antibiotics
L01DC01 Bleomycin (P) 6960000 U
L01DC03 Mitomycin (P) 4,22 g
L01E PROTEIN KINASE INHIBITORS 0,4860
L01EA BCR-ABL tyrosine kinase inhibitors 0,1211
L01EA01 Imatinib (O) 14400 g 0,4 g 0,0742
L01EA02 Dasatinib (O) 663 g 0,1 g 0,0137
L01EA03 Nilotinib (O) 8534,4 g 0,6 g 0,0293
L01EA04 Bosutinib (O) 551,6 g 0,4 g 0,0028
L01EA05 Ponatinib (O) 24,3 g 45 mg 0,0011
L01EB Epidermal growth factor receptor (EGFR) tyrosine kinase
inhibitors 0,0258
L01EB01 Gefitinib (O) 1665 g 0,25 g 0,0137
L01EB02 Erlotinib (O) 48 g 0,15 g 0,0007
L01EB03 Afatinib (O) 73,36 g 40 mg 0,0038
L01EB04 Osimertinib (O) 295,2 g 80 mg 0,0076
L01EC B-Raf serine-threonine kinase (BRAF) inhibitors 0,0205
L01EC02 Dabrafenib (O) 2979 g 0,3 g 0,0205
L01ED Anaplastic lymphoma kinase (ALK) inhibitors 0,0055
L01ED01 Crizotinib (O) 315 g 0,5 g 0,0013
L01ED02 Ceritinib (O) 315 g 0,45 g 0,0014
L01ED03 Alectinib (O) 974,4 g 1,2 g 0,0017
L01ED04 Brigatinib (O) 93,24 g 0,18 g 0,0011
L01EE Mitogen-activated protein kinase (MEK) inhibitors 0,0220
L01EE01 Trametinib (O) 21,36 g 2 mg 0,0220
L01EE04 selumetinib (O) 2,1 g
L01EF Cyclin-dependent kinase (CDK) inhibitors 0,0711
L01EF01 Palbociclib (O) 2657,025 g 94 mg 0,0582
L01EF02 Ribociclib (O) 2809,8 g 0,45 g 0,0129
L01EG Mammalian target of rapamycin (mTOR) kinase inhibitors 0,0101
L01EG01 Temsirolimus (P) 0,36 g 3,57 mg 0,0002
L01EG02 Everolimus (O) 48 g 10 mg 0,0099
L01EH Human epidermal growth factor receptor 2 (HER2) tyrosine
kinase inhibitors 0,0009
L01EH01 Lapatinib (O) 420 g 1,25 g 0,0007
L01EH03 Tucatinib (O) 54 g 0,6 g 0,0002
L01EJ Janus-associated kinase (JAK) inhibitors 0,0175
L01EJ01 Ruxolitinib (O) 254,8 g 30 mg 0,0175
L01EK Vascular endothelial growth factor receptor (VEGFR) tyrosine
kinase inhibitors 0,0050
L01EK01 Axitinib (O) 24,304 g 10 mg 0,0050
L01EL Bruton's tyrosine kinase (BTK) inhibitors 0,0521
L01EL01 Ibrutinib (O) 10617,6 g 0,42 g 0,0521
L01EX Other protein kinase inhibitors 0,1346
24/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01EX01 Sunitinib (O) 325,5 g 33 mg 0,0203
L01EX02 Sorafenib (O) 3718,4 g 0,8 g 0,0096
L01EX03 Pazopanib (O) 15234 g 0,8 g 0,0392
L01EX05 regorafenib (O) 201,6 g 0,12 g 0,0035
L01EX07 Cabozantinib (O) 477,72 g 60 mg 0,0164
L01EX08 Lenvatinib (O) 87,06 g 18 mg 0,0100
L01EX09 Nintedanib (O) 6126 g 0,38 g 0,0332
L01EX10 Midostaurin (O) 119 g 0,1 g 0,0025
L01F MONOCLONAL ANTIBODIES AND ANTIBODY DRUG
CONJUGATES
L01FA CD20 (Clusters of Differentiation 20) inhibitors
L01FA01 Rituximab (P) 2036,856 g
L01FA03 Obinutuzumab (P) 50 g
L01FB CD22 (Clusters of Differentiation 22) inhibitors
L01FB01 Inotuzumab ozogamicin (P) 0,016 g
L01FC CD38 (Clusters of Differentiation 38) inhibitors
L01FC01 Daratumumab (P) 760,6 g
L01FD HER2 (Human Epidermal Growth Factor Receptor 2)
inhibitors
L01FD01 Trastuzumab (P) 1632,15 g
L01FD02 Pertuzumab (P) 255,78 g
L01FD03 Trastuzumab emtansine (P) 124,72 g
L01FE EGFR (Epidermal Growth Factor Receptor) inhibitors
L01FE01 Cetuximab (P) 19,6 g
L01FE02 Panitumumab (P) 109,3 g
L01FF PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1)
inhibitors
L01FF01 Nivolumab (P) 294,72 g
L01FF02 Pembrolizumab (P) 438 g
L01FF03 Durvalumab (P) 318,5 g
L01FF05 Atezolizumab (P) 524,4 g
L01FG VEGF/VEGFR (Vascular Endothelial Growth Factor) inhibitors
L01FG01 Bevacizumab (P) 1214,5 g
L01FG02 Ramucirumab (P) 2,8 g
L01FX Other monoclonal antibodies and antibody drug conjugates
L01FX04 Ipilimumab (P) 2,7 g
L01FX05 Brentuximab vedotin (P) 13,1 g
L01FX07 Blinatumomab (P) 0,004 g
L01FX14 polatuzumab vedotin (P) 0,51 g
L01FX18 Amivantamab (P) 6,3 g
L01X OTHER ANTINEOPLASTIC AGENTS
L01XA Platinum compounds
L01XA01 Cisplatin (P) 174 g
L01XA02 Carboplatin (P) 2049 g
L01XA03 Oxaliplatin (P) 860 g
L01XB Methylhydrazines
L01XB01 Procarbazine (O) 262,5 g
L01XD Sensitizers used in photodynamic/radiation therapy
L01XD04 Aminolevulinic acid (O) 18 g
L01XF Retinoids for cancer treatment
L01XF01 Tretinoin (O) 9 g
L01XG Proteasome inhibitors
L01XG01 Bortezomib (P) 8,7465 g
L01XG02 Carfilzomib (P) 10,26 g
L01XK Poly (ADP-ribose) polymerase (PARP) inhibitors
L01XK01 Olaparib (O) 10761,6 g
L01XX Other antineoplastic agents
L01XX02 Asparaginase (P) 2550000 U
L01XX05 Hydroxycarbamide (O) 254750 g
L01XX11 Estramustine (O) 72,8 g
L01XX23 Mitotane (O) 3600 g
25/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L01XX24 Pegaspargase (P) 281250 U
L01XX27 Arsenic trioxide (P) 0,3 g
L01XX35 Anagrelide (O) 1,65 g
L01XX41 Eribulin (P) 0,3687 g
L01XX52 Venetoclax (O) 3938,48 g
L01XX73 Sotorasib (O) 172,8 g
L01XY Combinations of antineoplastic agents
L01XY02 Pertuzumab+Trastuzumab (P) 3445 ml
L02 ENDOCRINE THERAPY 4,7394
L02A HORMONES AND RELATED AGENTS 0,7576
L02AB Progestogens 0,0118
L02AB02 Medroxyprogesterone (O) 5745 g 1 g 0,0118
L02AE Gonadotropin releasing hormone analogues 0,7458
L02AE03 Goserelin (P) 9,2952 g 0,129 mg 0,1484
L02AE04 Triptorelin (P) 0,3108 g 0,1 mg 0,0064
L02AE04 Triptorelin (P) 38,4412 g 0,134 mg 0,5909
L02B HORMONE ANTAGONISTS AND RELATED AGENTS 3,9817
L02BA Anti-estrogens 0,8024
L02BA01 Tamoxifen (O) 6112,2 g 0,02 g 0,6295
L02BA03 Fulvestrant (P) 696,5 g 8,3 mg 0,1729
L02BB Anti-androgens 1,1581
L02BB03 Bicalutamide (O) 27742,4 g 0,05 g 1,1430
L02BB04 enzalutamide
(O) 1061,76 g 0,16 g 0,0137
L02BB05 Apalutamide (O) 172,8 g 0,24 g 0,0015
L02BG Aromatase inhibitors 1,9004
L02BG03 Anastrozole (O) 340,944 g 1 mg 0,7023
L02BG04 Letrozole (O) 1312,95 g 2,5 mg 1,0818
L02BG06 Exemestane (O) 1410,75 g 0,025 g 0,1162
L02BX Other hormone antagonists and related agents 0,1208
L02BX03 Abiraterone (O) 58650 g 1 g 0,1208
L03 IMMUNOSTIMULANTS 0,5084
L03A IMMUNOSTIMULANTS 0,5084
L03AA Colony stimulating factors 0,0976
L03AA02 Filgrastim (P) 9,7851 g 0,35 mg 0,0576
L03AA13 Pegfilgrastim (P) 5,826 g 0,3 mg 0,0400
L03AB Interferons 0,2994
L03AB04 Interferon alfa-2a (P) 1230000000 U 2000000 U 0,0013
L03AB07 Interferon beta-1a (P) 0,4547 g 0,0043 mg 0,2178
L03AB08 Interferon beta-1b (P) 72960000000 U 4000000 U 0,0376
L03AB11 Peginterferon alfa-2a (P) 0,035 g 0,026 mg 0,0028
L03AB13 Peginterferon beta-1a (P) 0,1726 g 8,9 mcg 0,0400
L03AX Other immunostimulants 0,1114
L03AX03 BCG bacteria (P) 4,175 g 1,8 mg 0,0048
L03AX13 Glatiramer acetate (P) 1029,6 g 0,02 g 0,1060
L03AX15 Mifamurtide (P) 0,192 g 0,7 mg 0,0006
L03AX16 Plerixafor (P) 0,456 g 16,8 mg 0,0001
L03AX80 Methyluracil (R) 300 g
L04 IMMUNOSUPPRESSANTS 7,2970
L04A IMMUNOSUPPRESSANTS 7,2970
L04AA Selective immunosuppressants 1,2287
L04AA03 Antilymphocyte immunoglobulin (horse) (P) 10 g
L04AA04 Rabbit anti-T-lymphocyte immunoglobulin (P) 20,65 g 0,1 g 0,0004
L04AA06 Mycophenolic acid (O) 290647,6 g 2 g 0,2994
L04AA06 Mycophenolic acid (P) 146 g 2 g 0,0002
L04AA10 Sirolimus (O) 23,67 g 0,003 g 0,0163
L04AA13 Leflunomide (O) 5487,3 g 0,02 g 0,5652
L04AA18 Everolimus (O) 0,36 g 1,5 mg 0,0005
L04AA23 Natalizumab (P) 45,9 g 0,01 g 0,0095
L04AA24 Abatacept (P) 202,25 g 0,027 g 0,0154
L04AA25 Eculizumab (P) 79,8 g 0,064 g 0,0026
L04AA26 Belimumab (P) 5,6 g 25 mg 0,0005
26/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
L04AA27 Fingolimod (O) 3,99 g 0,5 mg 0,0164
L04AA29 Tofacitinib
(O) 124,992 g 10 mg 0,0257
L04AA31 Teriflunomide (O) 700,504 g 14 mg 0,1031
L04AA33 Vedolizumab (P) 96,612 g 5,4 mg 0,0369
L04AA34 Alemtuzumab (P) 0,84 g 0,13 mg 0,0133
L04AA36 Ocrelizumab (P) 130,5 g 3,29 mg 0,0817
L04AA37 Baricitinib
(O) 3,92 g 4 mg 0,0020
L04AA40 Cladribine (O) 1,81 g 0,34 mg 0,0110
L04AA42 Siponimod (O) 15,354 g
L04AA44 Upadacitinib (O) 209,58 g 15 mg 0,0288
L04AA47 Inebilizumab (P) 1,2 g
L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors 1,4872
L04AB01 Etanercept (P) 1009 g 0,007 g 0,2969
L04AB02 Infliximab (P) 1013,3 g 3,75 mg 0,5566
L04AB04 Adalimumab (P) 757,4 g 2,9 mg 0,5380
L04AB05 Certolizumab pegol (P) 28,8 g 14 mg 0,0042
L04AB06 Golimumab (P) 73,65 g 1,66 mg 0,0914
L04AC Interleukin inhibitors 0,5350
L04AC02 Basiliximab (P) 1,44 g 0,04 g 0,0001
L04AC03 Anakinra (P) 59,7975 g 0,1 g 0,0012
L04AC05 Ustekinumab (P) 59,43 g 0,54 mg 0,2267
L04AC07 Tocilizumab (P) 1524,376 g 0,02 g 0,1570
L04AC10 Secukinumab (P) 451,05 g 10 mg 0,0929
L04AC13 Ixekizumab (P) 21,12 g 2,9 mg 0,0150
L04AC14 Sarilumab (P) 131,1 g 14,3 mg 0,0189
L04AC16 Guselkumab (P) 7,9 g 1,79 mg 0,0091
L04AC18 Risankizumab (P) 11,4 g 1,67 mg 0,0141
L04AD Calcineurin inhibitors 0,4489
L04AD01 Ciclosporin (O) 26942,5 g 0,25 g 0,2220
L04AD01 Ciclosporin (P) 95 g 0,25 g 0,0008
L04AD02 Tacrolimus (O) 548,6025 g 5 mg 0,2260
L04AD02 Tacrolimus (P) 0,3 g 5 mg 0,0001
L04AX Other immunosuppressants 3,5973
L04AX01 Azathioprine (O) 29980 g 0,15 g 0,4117
L04AX02 Thalidomide (O) 313,6 g 0,1 g 0,0065
L04AX03 Methotrexate (O) 3341,8 g 2,5 mg 2,7536
L04AX03 Methotrexate (P) 139,95 g 2,5 mg 0,1153
L04AX04 Lenalidomide (O) 427,77 g 0,01 g 0,0881
L04AX05 Pirfenidone (O) 19512,36 g 2,4 g 0,0167
L04AX06 Pomalidomide
(O) 18,144 g 3 mg 0,0125
L04AX07 Dimethyl fumarate (O) 44943,36 g 0,48 g 0,1929
M MUSCULO-SKELETAL SYSTEM 84,8775
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS 68,4088
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS,
NON-STEROIDS 68,3974
M01AB Acetic acid derivatives and related substances 8,5761
M01AB01 Indometacin (O) 2065,2 g 0,1 g 0,0425
M01AB05 Diclofenac (O) 294447 g 0,1 g 6,0654
M01AB05 Diclofenac (P) 7798,5 g 0,1 g 0,1606
M01AB05 Diclofenac (R) 12623,375 g 0,1 g 0,2600
M01AB15 Ketorolac (P) 1,8 g 30 mg 0,0001
M01AB16 Aceclofenac (O) 42012 g 0,2 g 0,4327
M01AB82 Diclofenac+Omeprazole (O) 78381 g 0,1 g 1,6146
M01AC Oxicams 3,6044
M01AC01 Piroxicam (O) 939,6 g 0,02 g 0,0968
M01AC05 Lornoxicam (O) 1962,96 g 0,012 g 0,3370
M01AC06 Meloxicam (O) 22912,2 g 0,015 g 3,1465
M01AC06 Meloxicam (P) 175,725 g 0,015 g 0,0241
27/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
M01AE Propionic acid derivatives 39,5075
M01AE01 Ibuprofen (O) 14553081,2 g 1,2 g 24,9821
M01AE01 Ibuprofen (P) 7830 g 1,2 g 0,0134
M01AE02 Naproxen (O) 697334 g 0,5 g 2,8729
M01AE03 Ketoprofen (O) 123697,375 g 0,15 g 1,6987
M01AE03 Ketoprofen (P) 12086 g 0,15 g 0,1660
M01AE03 Ketoprofen (R) 1,2 g 0,15 g <0,0001
M01AE17 Dexketoprofen (O) 81245,75 g 0,075 g 2,2315
M01AE17 Dexketoprofen (P) 3681,25 g 0,075 g 0,1011
M01AE52 Naproxen+Esomeprazole (O) 1802955 g 0,5 g 7,4280
M01AE82 Ibuprofen+Phenylephrine (O) 7982,4 g 1,2 g 0,0137
M01AG Fenamates 0,0050
M01AG02 Tolfenamic acid (O) 732 g 0,3 g 0,0050
M01AH Coxibs 9,4846
M01AH01 Celecoxib (O) 79634 g 0,2 g 0,8202
M01AH05 Etoricoxib (O) 252367,29 g 60 mg 8,6644
M01AX Other antiinflammatory and antirheumatic agents, non-steroids 7,2198
M01AX01 Nabumetone (O) 153000 g 1 g 0,3152
M01AX05 Glucosamine (O) 5027748,69 g 1,5 g 6,9046
M01C SPECIFIC ANTIRHEUMATIC AGENTS 0,0114
M01CC Penicillamine and similar agents 0,0114
M01CC01 Penicillamine (O) 2775 g 0,5 g 0,0114
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA10 Ketoprofen (C) 1330650 g
M02AA12 Naproxen (C) 1004135 g
M02AA13 Ibuprofen (C) 26462 pieces
M02AA13 Ibuprofen (C) 810500 g
M02AA15 Diclofenac (C) 482007 pieces
M02AA15 Diclofenac (C) 30657500 g
M02AA81 Ibuprofen+Levomenthol (C) 1867700 g
M02AC Preparations with salicylic acid derivatives
M02AC80 Methyl salicylate+Levomenthol+Eucalyptus oil+Turpentine oil
(C) 93063 g
M02AX Other topical products for joint and muscular pain
M02AX80 Nicoboxil+Nonivamide (C) 101340 g
M02AX90 Camphor+Salicylic acid+Turpentine oil+Venenum Viperae
berus (C) 836050 g
M02AX92 Benzyl nicotinate+Nonivamide+Camphor+Turpentine
oil+Dimethyl sulfoxide (C) 737300 g
M03 MUSCLE RELAXANTS 1,0042
M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
M03AB Choline derivatives
M03AB01 Suxamethonium chloride (P) 2881 g
M03AC Other quaternary ammonium compounds
M03AC04 Atracurium besilate (P) 3034,75 g
M03AC06 Pipecuronium bromide (P) 17,5 g
M03AC09 Rocuronium bromide (P) 1072 g
M03AX Other muscle relaxants, peripherally acting agents
M03AX01 Botulinum toxin (P) 1922300 U
M03B MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS 1,0042
M03BX Other centrally acting agents 1,0042
M03BX01 Baclofen (O) 4710,75 g 0,05 g 0,1941
M03BX01 Baclofen (P) 3,9608 g 0,55 mg 0,0148
M03BX02 Tizanidine (O) 4632,9 g 0,012 g 0,7953
M03C MUSCLE RELAXANTS, DIRECTLY ACTING AGENTS
M03CA Dantrolene and derivatives
M03CA01 Dantrolene (P) 3,12 g
M04 ANTIGOUT PREPARATIONS 10,6963
28/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
M04A ANTIGOUT PREPARATIONS 10,6963
M04AA Preparations inhibiting uric acid production 10,6778
M04AA01 Allopurinol (O) 1504129 g 0,4 g 7,7461
M04AA03 Febuxostat (O) 113856,96 g 0,08 g 2,9317
M04AB Preparations increasing uric acid excretion 0,0038
M04AB01 Probenecid (O) 50 g 1 g 0,0001
M04AB03 Benzbromarone (O) 180 g 0,1 g 0,0037
M04AC Preparations with no effect on uric acid metabolism 0,0147
M04AC01 Colchicine (O) 7,15 g 1 mg 0,0147
M05 DRUGS FOR TREATMENT OF BONE DISEASES 4,7681
M05B DRUGS AFFECTING BONE STRUCTURE AND
MINERALIZATION 4,7681
M05BA Bisphosphonates 0,7069
M05BA03 Pamidronic acid (P) 8,13 g 0,06 g 0,0003
M05BA04 Alendronic acid (O) 252 g 0,01 g 0,0519
M05BA06 Ibandronic acid (O) 1212,6 g 0,005 g 0,4996
M05BA06 Ibandronic acid (P) 0,006 g 0,006 g <0,0001
M05BA07 Risedronic acid (O) 357,14 g 0,005 g 0,1471
M05BA08 Zoledronic acid (P) 15,566 g 0,004 g 0,0080
M05BB Bisphosphonates, combinations 2,6112
M05BB03 Alendronic acid+Colecalciferol (O) 12675,88 g 10 mg 2,6112
M05BX Other drugs affecting bone structure and mineralization 1,4500
M05BX04 Denosumab (P) 232,294 g 0,33 mg 1,4500
M05BX05 Burosumab (P) 2,53 g
M09 OTHER DRUGS FOR DISORDERS OF THE MUSCULO-
SKELETAL SYSTEM
M09A OTHER DRUGS FOR DISORDERS OF THE MUSCULO-
SKELETAL SYSTEM
M09AX Other drugs for disorders of the musculo-skeletal system
M09AX10 Risdiplam (O) 0,6 g
N NERVOUS SYSTEM 148,2854
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AB Halogenated hydrocarbons
N01AB06 Isoflurane (I) 7500 ml
N01AB07 Desflurane (I) 63360 ml
N01AB08 Sevoflurane (I) 745250 ml
N01AF Barbiturates, plain
N01AF03 Thiopental (P) 2160 g
N01AH Opioid anesthetics
N01AH01 Fentanyl (I) 18,182 g
N01AH01 Fentanyl (P) 34,298 g
N01AH06 Remifentanil (P) 22,235 g
N01AX Other general anesthetics
N01AX03 Ketamine (P) 2107 g
N01AX07 Etomidate (P) 40,8 g
N01AX10 Propofol (P) 89540,5 g
N01AX13 Nitrous oxide (I) 11170000 ml
N01AX14 Esketamine (P) 1089 g
N01B ANESTHETICS, LOCAL
N01BB Amides
N01BB01 Bupivacaine (Infilt, P) 3211,2 g
N01BB01 Bupivacaine (P) 219,8 g
N01BB02 Lidocaine (endocerv, P) 200 g
N01BB02 Lidocaine (C) 2097 g
N01BB02 Lidocaine (C) 5650 ml
N01BB02 Lidocaine (NA) 20100 ml
N01BB02 Lidocaine (NA) 68722 g
N01BB02 Lidocaine (O) 79772 g
N01BB02 Lidocaine (P) 23476,15 g
N01BB03 Mepivacaine (dental) 1514,7 g
N01BB08 Articaine (P) 0,8 g
29/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N01BB09 Ropivacaine (P) 725,9 g
N01BB80 Articaine+Epinephrine (dental) 943160 ml
N01BB80 Articaine+Epinephrine (O) 602280 ml
N01BB81 Bupivacaine+Epinephrine (P) 82 g
N01BB81 Bupivacaine+Epinephrine (P) 248200 ml
N01BB82 Lidocaine+Epinephrine (dental) 51800 ml
N01BB83 Lidocaine+Prilocaine (C) 72046,5 g
N01BB86 Lidocaine+Chlorhexidine (urethral) 1410375 g
N01BC Esters of benzoic acid
N01BC01 Cocaine (NA) 30 g
N01BX Other local anesthetics
N01BX04 Capsaicin (C) 67,8718 g
N02 ANALGESICS 27,8706
N02A OPIOIDS 9,3531
N02AA Natural opium alkaloids 0,9453
N02AA01 Morphine (O) 5757,9 g 0,1 g 0,1186
N02AA01 Morphine (P) 758 g 0,03 g 0,0520
N02AA05 Oxycodone (O) 23151,3 g 0,075 g 0,6359
N02AA05 Oxycodone (P) 272,6 g 0,03 g 0,0187
N02AA08 Dihydrocodeine (O) 7836,6 g 0,15 g 0,1076
N02AA55 Oxycodone+Naloxone (O) 453,45 g 75 mg 0,0125
N02AB Phenylpiperidine derivatives 0,1259
N02AB02 Pethidine (P) 140,5 g 0,4 g 0,0007
N02AB02 Pethidine (P, V) 1408 g 0,4 g 0,0073
N02AB03 Fentanyl (O) 2,9652 g
N02AB03 Fentanyl (SL) 2,949 g 0,6 mg 0,0101
N02AB03 Fentanyl (TD) 62,8196 g 1,2 mg 0,1078
N02AE Oripavine derivatives 0,0183
N02AE01 Buprenorphine (TD) 10,6814 g 1,2 mg 0,0183
N02AJ Opioids in combination with non-opioid analgesics 6,4965
N02AJ06 Codeine+Paracetamol (O) 7516390 pieces 3 pieces 5,1611
N02AJ13 Tramadol+Paracetamol (O) 2164,5 g 150 mg 0,0297
N02AJ14 Tramadol+Dexketoprofen (O) 95073,75 g 150 mg 1,3056
N02AX Other opioids 1,7670
N02AX02 Tramadol (O) 254279 g 0,3 g 1,7460
N02AX02 Tramadol (P) 3055,25 g 0,3 g 0,0210
N02B OTHER ANALGESICS AND ANTIPYRETICS 17,3768
N02BA Salicylic acid and derivatives 0,9327
N02BA01 Acetylsalicylic acid (O) 1156337,76 g 3 g 0,7940
N02BA01 Acetylsalicylic acid (P) 27 g
N02BA80 Acetylsalicylic acid +Ascorbic acid (O) 201991,2 g 3 g 0,1387
N02BB Pyrazolones 0,0020
N02BB02 Metamizole sodium (O) 50 g 3 g <0,0001
N02BB02 Metamizole sodium (P) 1680 g 3 g 0,0012
N02BB02 Metamizole sodium (P, V) 1190 g 3 g 0,0008
N02BE Anilides 16,4421
N02BE01 Paracetamol (O) 18053987,2 g 3 g 12,3967
N02BE01 Paracetamol (P) 316560 g 3 g 0,2174
N02BE01 Paracetamol (R) 56152,15 g 3 g 0,0386
N02BE52 Paracetamol+Pseudoephedrine+Diphenhydramine (O) 32896 g 3 g 0,0226
N02BE75 Paracetamol+Guaifenesin+Phenylephrine (O) 158191 g 3 g 0,1086
N02BE81 Paracetamol+Chlorphenamine+Pseudoephedrine+Dextrometh
orphan (O) 416918 g 3 g 0,2863
N02BE83 Paracetamol+Caffeine (O) 235272 g 3 g 0,1615
N02BE84 Paracetamol+Phenylephrine+Ascorbic acid (O) 815071,25 g 3 g 0,5597
N02BE85 Paracetamol+Pheniramine+Ascorbic acid (O) 71018,24 g 3 g 0,0488
N02BE86 Paracetamol+Phenylephrine+Terpin hydrate+Ascorbic
acid+Caffeine (O) 268788 g 3 g 0,1846
N02BE87 Paracetamol+Pseudoephedrine (O) 60265 g 3 g 0,0414
N02BE91 Paracetamol+Ascorbic acid (O) 9688,8 g 3 g 0,0067
N02BE92 Paracetamol+Codeine (O) 1253650 g 3 g 0,8608
N02BE94 Paracetamol+Codeine+Caffeine (O) 1786764 g 3 g 1,2269
30/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N02BE95 Paracetamol+Phenylephrine (O) 27820 g 3 g 0,0191
N02BE97 Paracetamol+Pseudoephedrine+Dextromethorphan (O) 382394 g 3 g 0,2626
N02C ANTIMIGRAINE PREPARATIONS 1,1407
N02CC Selective serotonin (5HT1) agonists 1,1117
N02CC01 Sumatriptan (N) 1 g 0,02 g 0,0001
N02CC01 Sumatriptan (O) 23223 g 0,05 g 0,9568
N02CC03 Zolmitriptan (O) 76,47 g 2,5 mg 0,0630
N02CC04 Rizatriptan (O) 56,25 g 0,01 g 0,0116
N02CC07 Frovatriptan (O) 97,325 g 2,5 mg 0,0802
N02CD Calcitonin gene-related peptide (CGRP) antagonists 0,0291
N02CD01 Erenumab (P) 18,55 g 2,5 mg 0,0153
N02CD03 fremanezumab (P) 50,175 g 7,5 mg 0,0138
N03 ANTIEPILEPTICS 12,3166
N03A ANTIEPILEPTICS 12,3166
N03AA Barbiturates and derivatives 0,3440
N03AA02 Phenobarbital (O) 14485 g 0,1 g 0,2984
N03AA02 Phenobarbital (P) 120 g 0,1 g 0,0025
N03AA03 Primidone (O) 26200 g 1,25 g 0,0432
N03AA80 Benzobarbital (O) 90 g
N03AB Hydantoin derivatives 0,0387
N03AB02 Phenytoin (O) 5490 g 0,3 g 0,0377
N03AB02 Phenytoin (P) 147,5 g 0,3 g 0,0010
N03AD Succinimide derivatives 0,0172
N03AD01 Ethosuximide (O) 10425 g 1,25 g 0,0172
N03AE Benzodiazepine derivatives 0,5495
N03AE01 Clonazepam (O) 2133,96 g 0,008 g 0,5495
N03AF Carboxamide derivatives 2,6382
N03AF01 Carbamazepine (O) 878151 g 1 g 1,8089
N03AF02 Oxcarbazepine (O) 401505 g 1 g 0,8271
N03AF03 Rufinamide (O) 1480 g 1,4 g 0,0022
N03AG Fatty acid derivatives 1,6288
N03AG01 Valproic acid (O) 1171350 g 1,5 g 1,6086
N03AG01 Valproic acid (P) 2051,3 g 1,5 g 0,0028
N03AG04 Vigabatrin (O) 16850 g 2 g 0,0174
N03AX Other antiepileptics 7,1003
N03AX03 Sultiame (O) 4770 g 0,4 g 0,0246
N03AX09 Lamotrigine (O) 122867,8 g 0,3 g 0,8437
N03AX11 Topiramate (O) 40113 g 0,3 g 0,2754
N03AX12 Gabapentin (O) 1842411 g 1,8 g 2,1085
N03AX14 Levetiracetam (O) 615172,5 g 1,5 g 0,8448
N03AX14 Levetiracetam (P) 575 g 1,5 g 0,0008
N03AX15 Zonisamide (O) 43,4 g 0,2 g 0,0004
N03AX16 Pregabalin (O) 436014,25 g 0,3 g 2,9939
N03AX17 Stiripentol (O) 1815 g 1 g 0,0037
N03AX18 Lacosamide (O) 68,6 g 0,3 g 0,0005
N03AX22 perampanel (O) 2,016 g 8 mg 0,0005
N03AX23 Brivaracetam (O) 121,8 g 0,1 g 0,0025
N03AX24 Cannabidiol (O) 320 g 0,7 g 0,0009
N04 ANTI-PARKINSON DRUGS 3,6332
N04A ANTICHOLINERGIC AGENTS 0,5502
N04AA Tertiary amines 0,5502
N04AA01 Trihexyphenidyl (O) 2670,9 g 0,01 g 0,5502
N04B DOPAMINERGIC AGENTS 3,0830
N04BA Dopa and dopa derivatives 1,4234
N04BA03 Levodopa +Carbidopa+Entacapone (O) 66452,5 g 0,45 g 0,3042
N04BA80 Levodopa +Benserazide (O) 310370 g 0,6 g 1,0656
N04BA81 Levodopa +Carbidopa (intestin) 22316 g
N04BA81 Levodopa +Carbidopa (O) 15629 g 0,6 g 0,0537
N04BB Adamantane derivatives 0,2933
N04BB01 Amantadine (O) 28480 g 0,2 g 0,2933
N04BB01 Amantadine (P) 16 g
N04BC Dopamine agonists 0,7800
31/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N04BC04 Ropinirole (O) 1097,824 g 0,006 g 0,3769
N04BC05 Pramipexole (O) 462,1697 g 2,5 mg 0,3808
N04BC07 Apomorphine (P) 215,8 g 20 mg 0,0222
N04BD Monoamine oxidase type B inhibitors 0,5863
N04BD02 Rasagiline (O) 284,63 g 0,001 g 0,5863
N05 PSYCHOLEPTICS 45,7687
N05A ANTIPSYCHOTICS 10,1784
N05AA Phenothiazines with aliphatic side-chain 0,1470
N05AA01 Chlorpromazine (O) 10095,5 g 0,3 g 0,0693
N05AA01 Chlorpromazine (P) 33,5 g 0,1 g 0,0007
N05AA02 Levomepromazine (O) 11188 g 0,3 g 0,0768
N05AA02 Levomepromazine (P, V) 8 g 0,1 g 0,0002
N05AB Phenothiazines with piperazine structure 0,0786
N05AB02 Fluphenazine (P) 5,125 g 0,001 g 0,0106
N05AB03 Perphenazine (O) 397,2 g 0,03 g 0,0273
N05AB03 Perphenazine (P) 198,006 g 0,01 g 0,0408
N05AC Phenothiazines with piperidine structure 0,0009
N05AC01 Periciazine (O) 21,6 g 0,05 g 0,0009
N05AD Butyrophenone derivatives 0,8906
N05AD01 Haloperidol (O) 1803,485 g 0,008 g 0,4644
N05AD01 Haloperidol (P) 25 g 0,0033 g 0,0156
N05AD01 Haloperidol (P) 644,25 g 0,008 g 0,1659
N05AD03 Melperone (O) 34075 g 0,3 g 0,2340
N05AD08 Droperidol (P) 13,1 g 2,5 mg 0,0108
N05AE Indole derivatives 0,0804
N05AE03 Sertindole (O) 607,792 g 0,016 g 0,0783
N05AE04 Ziprasidone (O) 81,6 g 0,08 g 0,0021
N05AE05 Lurasidone (O) 1,0416 g 60 mg <0,0001
N05AF Thioxanthene derivatives 0,8348
N05AF01 Flupentixol (O) 347,9 g 0,006 g 0,1194
N05AF01 Flupentixol (P) 116,84 g 0,004 g 0,0602
N05AF03 Chlorprothixene (O) 27282,5 g 0,3 g 0,1873
N05AF05 Zuclopenthixol (O) 1310,5 g 0,03 g 0,0900
N05AF05 Zuclopenthixol (P) 42,5 g 0,03 g 0,0029
N05AF05 Zuclopenthixol (P) 2730 g 0,015 g 0,3749
N05AH Diazepines, oxazepines, thiazepines and oxepines 5,9685
N05AH02 Clozapine (O) 98186,75 g 0,3 g 0,6742
N05AH03 Olanzapine (O) 11638,9 g 0,01 g 2,3975
N05AH03 Olanzapine (P) 213,45 g 0,01 g 0,0440
N05AH04 Quetiapine (O) 553954,25 g 0,4 g 2,8528
N05AL Benzamides 0,1239
N05AL01 Sulpiride (O) 18312 g 0,8 g 0,0472
N05AL05 Amisulpride (O) 14910 g 0,4 g 0,0768
N05AN Lithium 0,3380
N05AN01 Lithium (O) 147660 g 0,9 g 0,3380
N05AX Other antipsychotics 1,7156
N05AX08 Risperidone (O) 1661,6 g 0,005 g 0,6846
N05AX08 Risperidone (P) 20,95 g 2,7 mg 0,0160
N05AX12 Aripiprazole (O) 6028,23 g 0,015 g 0,8279
N05AX12 Aripiprazole (P) 9,0675 g 0,015 g 0,0012
N05AX12 Aripiprazole (P) 663,6 g 0,0133 g 0,1028
N05AX13 Paliperidone (P) 96,825 g 2,5 mg 0,0798
N05AX15 Cariprazine (O) 4,998 g 3 mg 0,0034
N05B ANXIOLYTICS 12,9529
N05BA Benzodiazepine derivatives 12,9523
N05BA01 Diazepam (O) 27207,35 g 0,01 g 5,6046
N05BA01 Diazepam (P) 460,4 g 0,01 g 0,0948
N05BA01 Diazepam (R) 64,825 g 0,01 g 0,0134
N05BA06 Lorazepam (O) 1034,82 g 2,5 mg 0,8527
N05BA06 Lorazepam (P) 15,78 g 2,5 mg 0,0130
N05BA08 Bromazepam (O) 5379,42 g 0,01 g 1,1081
N05BA09 Clobazam (O) 368 g 0,02 g 0,0379
32/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N05BA12 Alprazolam (O) 2529,0875 g 0,001 g 5,2098
N05BA80 Phenazepam (O) 8,75 g 0,001 g 0,0180
N05BB Diphenylmethane derivatives <0,0001
N05BB01 Hydroxyzine (O) 0,4 g 0,075 g <0,0001
N05BE Azaspirodecanedione derivatives 0,0006
N05BE01 Buspirone (O) 9 g 0,03 g 0,0006
N05C HYPNOTICS AND SEDATIVES 22,6375
N05CD Benzodiazepine derivatives 0,2051
N05CD02 Nitrazepam (O) 222,3 g 0,005 g 0,0916
N05CD05 Triazolam (O) 0,015 g 0,25 mg 0,0001
N05CD08 Midazolam (O) 75,375 g 0,015 g 0,0104
N05CD08 Midazolam (P) 712,3 g 0,015 g 0,0978
N05CD08 Midazolam (P, R) 37,65 g 0,015 g 0,0052
N05CF Benzodiazepine related drugs 21,3026
N05CF01 Zopiclone (O) 60598,95 g 7,5 mg 16,6441
N05CF02 Zolpidem (O) 22234,52 g 0,01 g 4,5802
N05CF04 Eszopiclone (O) 76,104 g 2 mg 0,0784
N05CH Melatonin receptor agonists 0,6816
N05CH01 Melatonin (O) 661,81 g 2 mg 0,6816
N05CM Other hypnotics and sedatives 0,4481
N05CM09 Valerianae radix (O) 599130 pieces 3 pieces 0,4114
N05CM18 Dexmedetomidine (P) 17,8332 g 1 mg 0,0367
N06 PSYCHOANALEPTICS 46,5395
N06A ANTIDEPRESSANTS 40,7262
N06AA Non-selective monoamine reuptake inhibitors 1,9370
N06AA02 Imipramine (O) 45 g 0,1 g 0,0009
N06AA04 Clomipramine (O) 4425 g 0,1 g 0,0912
N06AA09 Amitriptyline (O) 56274,25 g 0,075 g 1,5456
N06AA10 Nortriptyline (O) 10897,5 g 0,075 g 0,2993
N06AB Selective serotonin reuptake inhibitors 24,0617
N06AB03 Fluoxetine (O) 39099,48 g 0,02 g 4,0271
N06AB04 Citalopram (O) 13565,14 g 0,02 g 1,3972
N06AB05 Paroxetine (O) 22728,6 g 0,02 g 2,3410
N06AB06 Sertraline (O) 173843,1 g 0,05 g 7,1621
N06AB08 Fluvoxamine (O) 980 g 0,1 g 0,0202
N06AB10 Escitalopram (O) 44244,28 g 0,01 g 9,1141
N06AF Monoamine oxidase inhibitors, non-selective 0,0115
N06AF04 Tranylcypromine (O) 56 g 0,01 g 0,0115
N06AG Monoamine oxidase type A inhibitors 0,0008
N06AG02 Moclobemide (O) 120 g 0,3 g 0,0008
N06AX Other antidepressants 14,7151
N06AX03 Mianserin (O) 50,4 g 0,06 g 0,0017
N06AX05 Trazodone (O) 21087 g 0,3 g 0,1448
N06AX11 Mirtazapine (O) 39220,65 g 0,03 g 2,6931
N06AX12 Bupropione (O) 159853,5 g 0,3 g 1,0976
N06AX14 Tianeptine (O) 25356,75 g 0,0375 g 1,3929
N06AX16 Venlafaxine (O) 212042,1 g 0,1 g 4,3679
N06AX17 Milnacipran (O) 8,4 g 0,1 g 0,0002
N06AX18 Reboxetine (O) 1,44 g 0,008 g 0,0004
N06AX21 Duloxetine (O) 82083,24 g 0,06 g 2,8181
N06AX22 Agomelatine (O) 14884,1 g 0,025 g 1,2264
N06AX26 Vortioxetine (O) 4718,42 g 10 mg 0,9720
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND
NOOTROPICS 2,1640
N06BA Centrally acting sympathomimetics 1,7780
N06BA04 Methylphenidate (O) 24284,16 g 0,03 g 1,6675
N06BA07 Modafinil (O) 864 g 0,3 g 0,0059
N06BA09 Atomoxetine (O) 4061,12 g 0,08 g 0,1046
N06BA12 Lisdexamfetamine dimesylate (O) 31,5 g
N06BC Xanthine derivatives
N06BC81 Caffeine citrate (O, P) 42 g
N06BX Other psychostimulants and nootropics 0,3860
33/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
N06BX03 Piracetam (O) 433464 g 2,4 g 0,3720
N06BX18 Vinpocetine (O) 101,5 g 15 mg 0,0139
N06BX83 Aminobutyric acid (O) 33485 g
N06D ANTI-DEMENTIA DRUGS 3,6493
N06DA Anticholinesterases 1,1914
N06DA02 Donepezil (O) 4337,76 g 7,5 mg 1,1914
N06DX Other anti-dementia drugs 2,4579
N06DX01 Memantine (O) 5960,68 g 0,02 g 0,6139
N06DX02 Ginkgo folium (O) 107419,8 g 0,12 g 1,8440
N06DX80 cerebrolysine (P) 360,46 g
N07 OTHER NERVOUS SYSTEM DRUGS 12,1568
N07A PARASYMPATHOMIMETICS 0,3566
N07AA Anticholinesterases 0,3566
N07AA01 neostigmine (P) 26,75 g 0,002 g 0,0276
N07AA02 Pyridostigmine bromide (O) 26892 g 0,18 g 0,3078
N07AA80 Neostigmine+Glycopyrronium (P) 10350 ml 1 ml 0,0213
N07AX Other parasympathomimetics
N07AX01 Pilocarpine (O) 1,26 g
N07B DRUGS USED IN ADDICTIVE DISORDERS 3,3302
N07BA Drugs used in nicotine dependence 1,7231
N07BA01 Nicotine (O) 16377,04 g 0,03 g 1,1245
N07BA01 Nicotine (TD) 3898,874 g 0,014 g 0,5737
N07BA03 Varenicline (O) 24,154 g 2 mg 0,0249
N07BB Drugs used in alcohol dependence 0,4209
N07BB01 Disulfiram (O) 33820 g 0,2 g 0,3483
N07BB01 Disulfiram (P) 80 g
N07BB03 Acamprosate (O) 347,652 g 2 g 0,0004
N07BB04 Naltrexone (O) 1598,8 g 50 mg 0,0659
N07BB05 nalmefene (O) 55,188 g 18 mg 0,0063
N07BC Drugs used in opioid dependence 1,1862
N07BC02 Methadone (O) 13848 g 0,025 g 1,1410
N07BC51 Buprenorphine+Naloxone (SL) 175,504 g 8 mg 0,0452
N07C ANTIVERTIGO PREPARATIONS 8,4395
N07CA Antivertigo preparations 8,4395
N07CA01 Betahistine (O) 84223,92 g 0,024 g 7,2290
N07CA02 Cinnarizine (O) 49865 g 0,09 g 1,1413
N07CA03 Flunarizine (O) 3,3 g 0,01 g 0,0007
N07CA80 Cinnarizine+Dimenhydrinate (O) 2990 g 90 mg 0,0684
N07X OTHER NERVOUS SYSTEM DRUGS 0,0305
N07XX Other nervous system drugs 0,0305
N07XX02 Riluzole (O) 1310,4 g 0,1 g 0,0270
N07XX06 Tetrabenazine (O) 120,4 g 0,1 g 0,0025
N07XX07 Fampridine (O) 10,08 g 20 mg 0,0010
N07XX14 Edaravone (P) 4,5 g
P ANTIPARASITIC PRODUCTS, INSECTICIDES AND
REPELLENTS 1,0909
P01 ANTIPROTOZOALS 0,8872
P01A AGENTS AGAINST AMOEBIASIS AND OTHER
PROTOZOAL DISEASES 0,1744
P01AB Nitroimidazole derivatives 0,1744
P01AB01 Metronidazole (O) 169330 g 2 g 0,1744
P01AB01 Metronidazole (O, V) 831 g
P01B ANTIMALARIALS 0,7128
P01BA Aminoquinolines 0,6861
P01BA02 Hydroxychloroquine (O) 171702 g 0,516 g 0,6855
P01BA03 Primaquine (O) 4,5 g 0,015 g 0,0006
P01BB Biguanides 0,0264
P01BB51 Proguanil+Atovaquone (O) 792 pieces 16 pieces 0,0001
P01BB51 Proguanil+Atovaquone (O) 51048 pieces 4 pieces 0,0263
P01BC Methanolquinolines 0,0001
P01BC01 Quinine (P) 60 g 1,5 g 0,0001
P01BD Diaminopyrimidines 0,0003
34/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
P01BD01 Pyrimethamine (O) 9,75 g 0,075 g 0,0003
P02 ANTHELMINTICS 0,2037
P02B ANTITREMATODALS 0,0001
P02BA Quinoline derivatives and related substances 0,0001
P02BA01 Praziquantel (O) 198 g 3 g 0,0001
P02C ANTINEMATODAL AGENTS 0,2036
P02CA Benzimidazole derivatives 0,2029
P02CA01 Mebendazole (O) 17140,6 g 0,2 g 0,1765
P02CA03 Albendazole (O) 5112 g 0,4 g 0,0263
P02CF Avermectines 0,0007
P02CF01 Ivermectin (O) 4,14 g 12 mg 0,0007
P03 ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES
AND REPELLENTS
P03A ECTOPARASITICIDES, INCL. SCABICIDES
P03AC Pyrethrines, incl. synthetic compounds
P03AC04 Permethrin (C) 160090 g
P03AX Other ectoparasiticides, incl. scabicides
P03AX01 Benzyl benzoate (C) 284790 g
R RESPIRATORY SYSTEM 96,3499
R01 NASAL PREPARATIONS 39,0823
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS
FOR TOPICAL USE 36,7791
R01AA Sympathomimetics, plain 23,3489
R01AA05 Oxymetazoline (N) 265,2525 g 0,4 mg 1,3660
R01AA07 Xylometazoline (N) 8537,2875 g 0,8 mg 21,9829
R01AB Sympathomimetics, combinations excl. corticosteroids 3,6750
R01AB83 Xylometazoline+Ipratropium bromide (N) 223180 ml 0,8 ml 0,5747
R01AB85 Xylometazoline+Dexpanthenol (N) 1204030 ml 0,8 ml 3,1003
R01AC Antiallergic agents, excl. corticosteroids 0,3890
R01AC03 Azelastine (N) 105,76 g 0,56 mg 0,3890
R01AD Corticosteroids 9,3661
R01AD01 Beclometasone (N) 5,21 g 0,4 mg 0,0268
R01AD05 Budesonide (N) 34,2561 g 0,2 mg 0,3528
R01AD08 Fluticasone (N) 89,718 g 0,2 mg 0,9241
R01AD09 Mometasone (N) 407,652 g 0,2 mg 4,1987
R01AD12 Fluticasone furoate (N) 177,1605 g 0,11 mg 3,3176
R01AD81 Fluticasone+Azelastine (N) 1060320 doses 4 doses 0,5461
R01AX Other nasal preparations
R01AX06 Mupirocin (N) 24 g
R01AX83 Retinol+Tocopherol (N) 146040 ml
R01B NASAL DECONGESTANTS FOR SYSTEMIC USE 2,3033
R01BA Sympathomimetics 2,3033
R01BA02 Pseudoephedrine (O) 156945,12 g 0,24 g 1,3471
R01BA81 Pseudoephedrine+Triprolidine (O) 29880,12 g 0,24 g 0,2565
R01BA84 Pseudoephedrine+Guaifenesin (O) 9267,6 g 0,24 g 0,0795
R01BA89 Pseudoephedrine+Loratadine (O) 11276,16 g 0,24 g 0,0968
R01BA93 Pseudoephedrine+Cetirizine (O) 60980,64 g 0,24 g 0,5234
R02 THROAT PREPARATIONS 2,6112
R02A THROAT PREPARATIONS 2,6112
R02AA Antiseptics 2,1806
R02AA06 Cetylpyridinium chloride (O) 1386 pieces
R02AA82 Benzydamine+Cetylpyridinium chloride (O) 818940 ml
R02AA82 Benzydamine+Cetylpyridinium chloride (O) 2041936 pieces 6 pieces 0,7010
R02AA89 Povidone, iodinated+Allantoin (O) 328650 ml
R02AA92 Dequalinium+Cinchocaine (O) 1075380 pieces 6 pieces 0,3692
R02AA94 Amylmetacresol+Dichlorobenzyl alcohol (O) 1252416 pieces 6 pieces 0,4300
R02AA95 Amylmetacresol+Dichlorobenzyl alcohol+Levomenthol (O) 1153632 pieces 6 pieces 0,3961
R02AA96 Amylmetacresol+Dichlorobenzyl alcohol+Ascorbic acid (O) 828120 pieces 6 pieces 0,2843
R02AA98 Cetylpyridinium chloride+Benzocaine (O) 18 pieces 6 pieces <0,0001
R02AD Anesthetics, local 0,0227
R02AD80 Lidocaine+Propyl parahydroxybenzoate (O) 65980 pieces 6 pieces 0,0227
R02AX Other throat preparations 0,4080
35/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R02AX01 Flurbiprofen (O) 8713,74 g 44 mg 0,4080
R02AX80 Thyme herb+Sage leaf (O) 23880 ml
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES 27,5760
R03A ADRENERGICS, INHALANTS 20,0939
R03AC Selective beta-2-adrenoceptor agonists 3,5904
R03AC02 Salbutamol (I) 935,452 g 0,8 mg 2,4087
R03AC02 Salbutamol (I) 1367,6 g 0,01 g 0,2817
R03AC04 Fenoterol (I) 56,8 g 0,6 mg 0,1950
R03AC12 Salmeterol (I) 3,717 g 0,1 mg 0,0766
R03AC13 Formoterol (I) 4,3448 g 0,024 mg 0,3729
R03AC18 Indacaterol (I) 18,5985 g 0,15 mg 0,2554
R03AK Adrenergics in combination with corticosteroids or other drugs,
excl. anticholinergics 12,5187
R03AK06 Salmeterol+Fluticasone (I) 518280 doses 4 doses 0,2669
R03AK06 Salmeterol+Fluticasone (I) 2082420 doses 2 doses 2,1448
R03AK07 Formoterol+Budesonide (I) 1066080 doses 2 doses 1,0980
R03AK07 Formoterol+Budesonide (I) 6442020 doses 4 doses 3,3176
R03AK08 Formoterol+Beclometasone (I) 3817980 doses 4 doses 1,9662
R03AK10 Vilanterol+Fluticasone furoate (I) 1758090 doses 1 doses 3,6216
R03AK13 Salbutamol+Beclometasone (I) 201200 doses 4 doses 0,1036
R03AL Adrenergics in combinations with anticholinergics incl. triple
combinations with corticosteroids 3,9848
R03AL01 Fenoterol+Ipratropium bromide (I) 221780 ml 16 ml 0,0286
R03AL01 Fenoterol+Ipratropium bromide (I) 2585200 doses 6 doses 0,8876
R03AL03 Vilanterol+Umeclidinium (I) 402690 doses 1 doses 0,8295
R03AL04 Indacaterol+Glycopyrronium (I) 160260 doses 1 doses 0,3301
R03AL05 Formoterol+Aclidinium (I) 366540 doses 2 doses 0,3775
R03AL06 Olodaterol+Tiotropium (I) 646380 doses 2 doses 0,6658
R03AL07 Formoterol+Glycopyrronium (I) 279960 doses 4 doses 0,1442
R03AL08 Vilanterol+Umeclidinium+Fluticasone furoate (I) 103800 doses 1 doses 0,2138
R03AL09 Formoterol+Glycopyrronium+Beclometasone (I) 912720 doses 4 doses 0,4700
R03AL11 Formoterol+Glycopyrronium+Budesonide (I) 73320 doses 4 doses 0,0378
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES,
INHALANTS 4,6161
R03BA Glucocorticoids 1,5513
R03BA01 Beclometasone (I) 0,1 g 1,5 mg 0,0001
R03BA02 Budesonide (I) 210,3 g 1,5 mg 0,2888
R03BA02 Budesonide (I) 278,972 g 0,8 mg 0,7183
R03BA05 Fluticasone (I) 158,457 g 0,6 mg 0,5440
R03BB Anticholinergics 3,0648
R03BB01 Ipratropium bromide (I) 19,66 g 0,12 mg 0,3375
R03BB01 Ipratropium bromide (I) 33,105 g 0,3 mg 0,2273
R03BB04 Tiotropium (I) 3,2122 g 0,005 mg 1,3234
R03BB05 Aclidinium (I) 126,5074 g 0,644 mg 0,4047
R03BB06 Glycopyrronium (I) 7,2362 g 44 mcg 0,3388
R03BB07 Umeclidinium (I) 11,5649 g 55 mcg 0,4331
R03C ADRENERGICS FOR SYSTEMIC USE 0,0980
R03CC Selective beta-2-adrenoceptor agonists 0,0980
R03CC02 Salbutamol (O) 570,96 g 0,012 g 0,0980
R03CC02 Salbutamol (P) 0,095 g 0,012 g <0,0001
R03D OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY
DISEASES 2,7680
R03DA Xanthines 1,0798
R03DA04 Theophylline (O) 206480 g 0,4 g 1,0633
R03DA05 Aminophylline (P) 4796,7 g 0,6 g 0,0165
R03DC Leukotriene receptor antagonists 1,5992
R03DC03 Montelukast (O) 7763,308 g 0,01 g 1,5992
R03DX Other systemic drugs for obstructive airway diseases 0,0890
R03DX05 Omalizumab (P) 209,7 g 0,016 g 0,0270
R03DX07 Roflumilast (O) 0,095 g 0,5 mg 0,0004
R03DX09 Mepolizumab (P) 68 g 3,6 mg 0,0389
R03DX10 Benralizumab (P) 5,94 g 0,54 mg 0,0227
36/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R05 COUGH AND COLD PREPARATIONS 7,4035
R05C EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH
SUPPRESSANTS 7,2390
R05CA Expectorants 0,0077
R05CA03 Guaifenesin (O) 3360 g 0,9 g 0,0077
R05CA12 Hederae helicis folium (O) 166632 pieces
R05CA12 Hederae helicis folium (O) 7406965 ml
R05CA86 Iceland moss (O) 6530550 ml
R05CA87 Distillate of rectified essential oils of eucalyptus, sweet orange,
myrtle and lemon (O) 2019220 pieces
R05CA88 Thyme herb+Wild thyme+Plantain (O) 525900 ml
R05CA89 Thyme herb+Hederae helicis folium (O) 387600 ml
R05CA91 Thyme herb+Marshmallow root (O) 210420 pieces
R05CA91 Thyme herb+Marshmallow root (O) 4960050 ml
R05CA92 Thyme herb (O) 138520 pieces
R05CB Mucolytics 7,2313
R05CB01 Acetylcysteine (I, P) 1077 g
R05CB01 Acetylcysteine (O) 1107653,2 g 0,5 g 4,5634
R05CB01 Acetylcysteine (P) 5892 g
R05CB02 Bromhexine (O) 6919,84 g 0,024 g 0,5939
R05CB03 Carbocisteine (O) 176156,25 g 1,5 g 0,2419
R05CB06 Ambroxol (O) 105584,85 g 0,12 g 1,8125
R05CB13 Dornase alfa (I) 23,715 g 2,5 mg 0,0195
R05D COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH
EXPECTORANTS 0,0901
R05DB Other cough suppressants 0,0901
R05DB09 Oxeladin (O) 3498,25 g 0,08 g 0,0901
R05F COUGH SUPPRESSANTS AND EXPECTORANTS,
COMBINATIONS 0,0744
R05FA Opium derivatives and expectorants 0,0744
R05FA80 Codeine+Guaifenesin (O) 1083750 ml 30 ml 0,0744
R05X OTHER COLDPREPARATIONS
R05XA Other cold combination preparations
R05XA80 Gentian root+Primula flower+Common sorrel+Elder
flower+Verbena herb (O) 1700780 pieces
R05XA80 Gentian root+Primula flower+Common sorrel+Elder
flower+Verbena herb (O) 2129200 ml
R05XA82 Ibuprofen+Pseudoephedrine (O) 5508 g
R06 ANTIHISTAMINES FOR SYSTEMIC USE 19,6762
R06A ANTIHISTAMINES FOR SYSTEMIC USE 19,6762
R06AA Aminoalkyl ethers 0,4448
R06AA02 Diphenhydramine (O) 10 g 0,2 g 0,0001
R06AA02 Diphenhydramine (P) 12 g
R06AA04 Clemastine (O) 387,38 g 0,002 g 0,3990
R06AA04 Clemastine (P) 44,34 g 0,002 g 0,0457
R06AD Phenothiazine derivatives 0,0002
R06AD02 Promethazine (O) 2 g 0,025 g 0,0002
R06AE Piperazine derivatives 9,8576
R06AE07 Cetirizine (O) 45436,995 g 0,01 g 9,3598
R06AE09 Levocetirizine (O) 1208,33 g 0,005 g 0,4978
R06AX Other antihistamines for systemic use 9,3737
R06AX13 Loratadine (O) 19838,1 g 0,01 g 4,0865
R06AX15 Mebhydrolin (O) 29 g 0,2 g 0,0003
R06AX17 Ketotifen (O) 3,69 g 0,002 g 0,0038
R06AX22 Ebastine (O) 7135 g 0,01 g 1,4698
R06AX27 Desloratadine (O) 2682,32 g 0,005 g 1,1051
R06AX28 Rupatadine (O) 890,48 g 0,01 g 0,1834
R06AX29 Bilastine (O) 24513,2 g 20 mg 2,5248
R07 OTHER RESPIRATORY SYSTEM PRODUCTS 0,0006
R07A OTHER RESPIRATORY SYSTEM PRODUCTS 0,0006
R07AA Lung surfactants 0,0005
R07AA81 Porcine lung phospholipids (endotrach) 39,84 g 0,16 g 0,0005
37/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
R07AX Other respiratory system products 0,0001
R07AX02 ivacaftor (O) 16,8 g 0,3 g 0,0001
R07AX32 Ivacaftor+Tezacaftor+Elexacaftor (O) 42 g
S SENSORY ORGANS 36,0108
S01 OPHTHALMOLOGICALS 36,0108
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA01 Chloramphenicol (S) 138030 ml
S01AA12 Tobramycin (S) 30315 ml
S01AA12 Tobramycin (S) 51618 g
S01AA13 Fusidic acid (S) 32070 g
S01AD Antivirals
S01AD03 Aciclovir (S) 3514,5 g
S01AE Fluoroquinolones
S01AE03 Ciprofloxacin (S) 8,07 g
S01AE03 Ciprofloxacin (S) 10885 ml
S01AE05 Levofloxacin (S) 32000 ml
S01AE07 Moxifloxacin (S) 13950 ml
S01AX Other antiinfectives
S01AX18 Povidone, iodinated (S) 280 ml
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA01 Dexamethasone (S) 220 pieces
S01BA01 Dexamethasone (S) 16254,7 g
S01BA01 Dexamethasone (S) 148315 ml
S01BA02 Hydrocortisone (S) 3978 g
S01BA09 Clobetasone (S) 30820 ml
S01BA14 Loteprednol (S) 9785 ml
S01BC Antiinflammatory agents, non-steroids
S01BC03 Diclofenac (S) 15 ml
S01BC05 Ketorolac (S) 5000 ml
S01BC10 Nepafenac (S) 21955 ml
S01BC11 Bromfenac (S) 12375 ml
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN
COMBINATION
S01CA Corticosteroids and antiinfectives in combination
S01CA80 Dexamethasone+Neomycin+Polymyxin B (S) 49635 ml
S01CA81 Dexamethasone+Tobramycin (S) 16030 g
S01CA81 Dexamethasone+Tobramycin (S) 41225 ml
S01CA82 Dexamethasone+Chloramphenicol (S) 51642,5 g
S01CA82 Dexamethasone+Chloramphenicol (S) 447920 ml
S01CA84 Dexamethasone+Levofloxacin (S) 865 ml
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS 36,0108
S01EA Sympathomimetics in glaucoma therapy 0,0261
S01EA05 Brimonidine (S) 2530 ml 0,2 ml 0,0261
S01EB Parasympathomimetics 0,0177
S01EB01 Pilocarpine (S) 2670 ml 0,4 ml 0,0138
S01EB02 Carbachol (S) 768 ml 0,4 ml 0,0040
S01EB09 Acetylcholine chloride (S) 0,2 g
S01EC Carbonic anhydrase inhibitors 3,7834
S01EC01 Acetazolamide (O) 25870 g 0,75 g 0,0711
S01EC01 Acetazolamide (P) 25 g 0,75 g 0,0001
S01EC03 Dorzolamide (S) 154225 ml 0,3 ml 1,0590
S01EC04 Brinzolamide (S) 152685 ml 0,2 ml 1,5726
S01EC80 Brinzolamide+Brimonidine (S) 104925 ml 0,2 ml 1,0807
S01ED Beta blocking agents 24,3791
S01ED01 Timolol (S) 24270 ml 0,2 ml 0,2500
S01ED01 Timolol (S) 245445 g 40 mg 12,6401
S01ED02 Betaxolol (S) 76575 ml 0,2 ml 0,7887
S01ED80 Timolol+Dorzolamide (S) 301550 ml 0,2 ml 3,1059
S01ED81 Timolol+Travoprost (S) 39262,5 ml 0,2 ml 0,4044
S01ED82 Timolol+Bimatoprost (S) 107109 ml 0,2 ml 1,1032
38/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
S01ED83 Timolol+Brinzolamide (S) 227515 ml 0,2 ml 2,3433
S01ED84 Timolol+Latanoprost (S) 73820 ml 0,2 ml 0,7603
S01ED85 Timolol+Tafluprost (S) 289638 ml 0,2 ml 2,9832
S01EE Prostaglandin analogues 7,8045
S01EE01 Latanoprost (S) 263740 ml 0,1 ml 5,4329
S01EE03 Bimatoprost (S) 261 ml 0,1 ml 0,0054
S01EE04 Travoprost (S) 56862,5 ml 0,1 ml 1,1713
S01EE05 Tafluprost (S) 174024 ml 0,3 ml 1,1949
S01F MYDRIATICS AND CYCLOPLEGICS
S01FA Anticholinergics
S01FA01 Atropine (S) 615 ml
S01FA04 Cyclopentolate (S) 30800 ml
S01FA06 Tropicamide (S) 16630 ml
S01FA80 Tropicamide+Phenylephrine+Lidocaine (int.cam) 1480 pieces
S01FB Sympathomimetics excl. antiglaucoma preparations
S01FB01 Phenylephrine (S) 7735 ml
S01G DECONGESTANTS AND ANTIALLERGICS
S01GA Sympathomimetics used as decongestants
S01GA02 Tetryzoline (S) 276225 ml
S01GX Other antiallergics
S01GX01 Cromoglicic acid (S) 110210 ml
S01GX07 Azelastine (S) 49782 ml
S01GX09 Olopatadine (S) 49955 ml
S01H LOCAL ANESTHETICS
S01HA Local anesthetics
S01HA03 Tetracaine (S) 24780 ml
S01HA04 Proxymetacaine (S) 37875 ml
S01J DIAGNOSTIC AGENTS
S01JA Colouring agents
S01JA01 Fluorescein (P) 362 g
S01JA01 Fluorescein (P) 2820 ml
S01JA81 Fluorescein+Oxybuprocaine+Chlorobutanol (S) 2525 ml
S01K SURGICAL AIDS
S01KA Viscoelastic substances
S01KA02 Hypromellose (S) 5940 ml
S01L OCULAR VASCULAR DISORDER AGENTS
S01LA Antineovascularisation agents
S01LA01 Verteporfin (P) 3 pieces
S01LA05 aflibercept (S) 205 pieces
S01LA06 Brolucizumab (S) 0,516 g
S01X OTHER OPHTHALMOLOGICALS
S01XA Other ophthalmologicals
S01XA03 Sodium chloride (S) 1151,5 g
S01XA18 Ciclosporin (S) 14535 ml
S01XA80 Retinol+Dexpanthenol (S) 6041 g
S01XA81 Carbomer (S) 188900 g
S01XA82 Hypromellose (S) 223620 ml
S01XA85 Hypromellose+Dextran (S) 410355 ml
S01XA86 cytochrome C+Adenosine+Nicotinamide (S) 90 ml
S02 OTOLOGICALS
S02C CORTICOSTEROIDS AND ANTIINFECTIVES IN
COMBINATION
S02CA Corticosteroids and antiinfectives in combination
S02CA81 Dexamethasone+Neomycin+Acetic acid, glacial (A) 4210 ml
S02CA82 Hydrocortisone+Ciprofloxacin (A) 143170 ml
S02D OTHER OTOLOGICALS
S02DA Analgesics and anesthetics
S02DA81 Phenazone+Lidocaine (A) 1875 ml
T HERBAL MEDICINAL PRODUCTS
T01 HERBAL MEDICINAL PRODUCTS
T01R HERBAL MEDICINAL PRODUCTS
T01RS Herbal medicinal products
39/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
T01RS01 herbal preparation (O) 505900 pieces
T01RS01 herbal preparation (O) 8862890 ml
T01RS02 homeopathic preparations (A) 5420 ml
T01RS02 homeopathic preparations (C) 617000 g
T01RS02 homeopathic preparations (O) 1940 g
T01RS02 homeopathic preparations (O) 1326010 pieces
T01RS02 homeopathic preparations (O) 1683700 ml
V VARIOUS 0,2127
V01 ALLERGENS
V01A ALLERGENS
V01AA Allergen extracts
V01AA02 Grass pollen (O) 226 pieces
V01AA02 Grass pollen (P) 225 pieces
V01AA03 House dust mites (O) 253 pieces
V01AA03 House dust mites (P) 30 ml
V01AA03 House dust mites (P) 268 pieces
V01AA05 Tree pollen (P) 482 pieces
V01AA05 Tree pollen (SL) 463 pieces
V01AA07 Allergen products (insects) (P) 330 pieces
V01AA11 Animals (O) 34 pieces
V01AA80 Tree and grass pollen (O) 159 pieces
V01AA80 Tree and grass pollen (P) 40 pieces
V01AA83 Grass pollen+Flowers (O) 18 pieces
V01AA84 Tree and flower pollen (O) 18 pieces
V03 ALL OTHER THERAPEUTIC PRODUCTS 0,2127
V03A ALL OTHER THERAPEUTIC PRODUCTS 0,2127
V03AB Antidotes
V03AB04 Pralidoxime (O, P) 120 g
V03AB06 Sodium thiosulphate (P) 1200 g
V03AB09 Dimercaprol (P) 4,8 g
V03AB14 Protamine sulfate (P) 214,5 g
V03AB15 Naloxone (N) 3,6 g
V03AB15 Naloxone (P) 1,172 g
V03AB16 Ethanol (P) 23400 ml
V03AB17 Methylthioninium chloride (P) 193,6 g
V03AB19 Physostigmine (P) 0,15 g
V03AB21 Potassium iodide (O) 78 g
V03AB25 Flumazenil (P) 0,3 g
V03AB32 Glutathione (P) 630 g
V03AB33 Hydroxocobalamin (P) 110 g
V03AB34 Fomepizole (P) 20,5 g
V03AB35 Sugammadex (P) 102 g
V03AB37 Idarucizumab (P) 115 g
V03AB81 Obidoxime chloride+Atropine (P) 100 pieces
V03AC Iron chelating agents
V03AC01 Deferoxamine (P) 60 g
V03AC02 Deferiprone (O) 900 g
V03AC03 Deferasirox (O) 6285,6 g
V03AE Drugs for treatment of hyperkalemia and hyperphosphatemia 0,1558
V03AE01 Polystyrene sulfonate (O, R) 1774155,5 g 45 g 0,0812
V03AE02 Sevelamer (O) 185904 g 6,4 g 0,0598
V03AE03 Lanthan (O) 16132,5 g 2,25 g 0,0148
V03AF Detoxifying agents for antineoplastic treatment 0,0569
V03AF01 Mesna (P) 5268 g
V03AF03 Calcium folinate (O) 38,25 g 0,06 g 0,0013
V03AF07 Rasburicase (P) 0,585 g 0,014 g 0,0001
V03AF09 Glucarpidase (P) 8000 U
V03AF10 Sodium levofolinate (P) 808,5 g 0,03 g 0,0555
V03AH Drugs for treatment of hypoglycemia
V03AH01 Diazoxide (O) 10 g
V03AN Medical gases
V03AN01 Oxygen (I) 756792000 ml
40/41
Estonian Statistics on Medicines 2021
ATC code ATC group / INN (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/
day
V03AN05 Air, medicinal (I) 4830000 ml
V04 DIAGNOSTIC AGENTS
V04C OTHER DIAGNOSTIC AGENTS
V04CD Tests for pituitary function
V04CD04 Corticorelin (P) 0,0014 g
V04CF Tuberculosis diagnostics
V04CF01 Tuberculin (P) 4800 U
V04CJ Tests for thyreoidea function
V04CJ02 Protirelin (P) 0,001 g
V04CX Other diagnostic agents
V04CX01 Indocyanine green (P) 8,4 g
V04CX03 Methacholine (I) 37,53 g
V04CX04 Mannitol (I) 72,39 g
V04CX06 Hexaminolevulinate (P) 20,06 g
V04CX87 Carbon monoxide+Helium (I) 20000 ml
V07 ALL OTHER NON-THERAPEUTIC PRODUCTS
V07A ALL OTHER NON-THERAPEUTIC PRODUCTS
V07AB Solvents and diluting agents, incl. irrigating solutions
V07AB80 Sodium chloride (P) 9680052 ml
V07AB83 Water for injection (NA) 38910000 ml
V07AB83 Water for injection (P) 2400000 ml
V08 CONTRAST MEDIA
V08A X-RAY CONTRAST MEDIA, IODINATED
V08AA Watersoluble, nephrotropic, high osmolar X-ray contrast media
V08AA01 Sodium amidotrizoate+Meglumine Amidotrizoate (P) 4000 ml
V08AB Watersoluble, nephrotropic, low osmolar X-ray contrast media
V08AB02 Iohexol (P) 1907365,5 g
V08AB05 Iopromide (P) 1133405 g
V08AB09 Iodixanol (P) 2838794 g
V08AD Non-watersoluble X-ray contrast media
V08AD01 Ethyl esters of iodised fatty acids (P) 72 g
V08B X-RAY CONTRAST MEDIA, NON-IODINATED
V08BA Barium sulfate containing X-ray contrast media
V08BA01 Barium sulfate (O) 134091,92 g
V08C MAGNETIC RESONANCE IMAGING CONTRAST MEDIA
V08CA Paramagnetic contrast media
V08CA01 Gadopentetic acid (P) 3120 ml
V08CA02 Gadoteric acid (P) 61550 ml
V08CA09 Gadobutrol (P) 90085 ml
V08CA10 Gadoxetic acid (P) 5800 ml
V08D ULTRASOUND CONTRAST MEDIA
V08DA Ultrasound contrast media
V08DA05 Sulfur hexafluoride, phospholipid microspheres (P) 150 ml
V09 DIAGNOSTIC RADIOPHARMACEUTICALS
V09A CENTRAL NERVOUS SYSTEM
V09AB Iodine (123I) compounds
V09AB03 Ioflupane (123I) (P) 480 ml
V09F THYROID
V09FX Various thyroid diagnostic radiopharmaceuticals
V09FX01 Technetium (99mTc) pertechnetate (S) 80 pieces
V10 THERAPEUTIC RADIOPHARMACEUTICALS
V10X OTHER THERAPEUTIC RADIOPHARMACEUTICALS
V10XA Iodine (131I) compounds
V10XA01 Sodium iodide (131I) (O) 86 pieces
41/41
| Nimi | K.p. | Δ | Viit | Tüüp | Org | Osapooled |
|---|---|---|---|---|---|---|
| Inquiry | 26.01.2025 | 1 | RST-1/4774-3 | Sissetulev kiri | ra | Organisation for Economic Co-operation and Development |
| Answers to Inquiry | 27.12.2024 | 3 | RST-1/4774-2 | Väljaminev kiri | ra | Organisation for Economic Co-operation and Development |
| Answers to Inquiry | 27.12.2024 | 3 | RST-1/4774-2 | Väljaminev kiri | ra | Organisation for Economic Co-operation and Development |
| Inquiry | 27.12.2024 | 3 | RST-1/4774-1 | Sissetulev kiri | ra | Organisation for Economic Co-operation and Development |
| Inquiry | 27.12.2024 | 3 | RST-1/4774-1 | Sissetulev kiri | ra | Organisation for Economic Co-operation and Development |